Area of Interest:

Pharmacology and Toxicology

100%

Pharmaceutical Biology

62%

Pharmacogenetics

90%

Drug Discovery

75%

Pharmacy

55%

Research Publications in Numbers

Books
0

Chapters
0

Articles
134

Abstracts
0

Selected Publications

Zhang, W., A. Welihinda, J. Mechanic, H.F. Ding and L. Zhu et al., 2011. EGT1442, a potent and selective SGLT2 inhibitor attenuates blood glucose and HbA1c levels in db/db mice and prolongs the survival of stroke-prone rats. Pharmacol. Res., (In Press). 10.1016/j.phrs.2011.01.001.
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Wei, H., A. Koivisto, M. Saarnilehto, H. Chapman and K. Kuokkanen et al., 2011. Spinal transient receptor potential ankyrin 1 channel contributes to central pain hypersensitivity in various pathophysiological conditions in the rat. Pain, 10.1016/j.pain.2010.11.031.
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Gong, N., A.N. Ma, L.J. Zhang, X.S. Lu, Y.H. Zhang, M. Xu and Y.X. Wang, 2011. Site-specific PEGylation of exenatide analogues markedly improved their glucoregulatory activity. Br. J. Pharmacol., 10.1111/j.1476-5381.2011.01227.x.
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Zhao, W.J., Z.Y. Gao, H. Wei, H.Z. Nie, Q. Zhao, X.J. Zhou and Y.X. Wang, 2010. Spinal D-Amino acid oxidase contributes to neuropathic pain in rats. J. Pharmacol. Exp. Ther., 332: 248-254.
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Xin, Y.F., X. Li, B. Hao, N. Gong, W.Q. Sun, R. Konno and Y.X. Wang, 2010. Indispensable but insufficient role of renal D-amino acid oxidase in chiral inversion of NG-nitro-D-arginine. Chem. Biodivers, 7: 1413-1423.
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Wei, H., B. Hao, J.L. Huang, A.N. Ma, X.Y. Li, Y.X. Wang and A. Pertovaara, 2010. Intrathecal administration of a gap junction decoupler, an inhibitor of Na⁺-K⁺-2Cl^- cotransporter 1, or a GABA_A receptor agonist attenuates mechanical pain hypersensitivity induced by REM sleep deprivation in the rat. Pharmacol. Biochem. Behav., 97: 377-383.
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Ma, A.N., W.L. Huang, Z.N. Wu, J.F. Hu, T. Li, X.J. Zhou and Y.X. Wang, 2010. Induced epigenetic modifications of the promoter chromatin silence survivin and inhibit tumor growth. Biochem. Biophy. Res. Commun., 393: 592-597.
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Ma, A.N., J. Lu, X.J. Zhou and Y.X. Wang, 2010. Histone deacetylation directs DNA methylation in survivin gene silencing. Biochem. Biophy. Res. Commun., 404: 268-272.
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Hao, B., Z.W. Chen, X.J. Zhou, P.I. Zimin, G.P. Miljanich, H. Wulff and Y.X. Wang, 2010. Identification of phase-I metabolites and chronic toxicity study of the Kv1.3 blocker PAP-1 (5-(4-phenoxybutoxy)psoralen) in the rat. Xenobiotica. 10.3109/00498254.2010.532886.
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Gong, N., Z.Y. Gao, Y.C. Wang, X.Y. Li, J.L. Huang, K. Hashimoto and Y.X. Wang, 2010. A series of D-amino acid oxidase inhibitors specifically prevents and reverses formalin-induced tonic pain in rats. J. Pharmacol. Exp. Ther., 336: 282-293.
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