Dr. Leonard  Preston Mercer
My Social Links

Dr. Leonard Preston Mercer

Professor
University of South Florida, USA


Highest Degree
Ph.D. in Biochemistry from Louisiana State University, Louisiana

Share this Profile

Biography

Dr. L. Preston Mercer is currently working as Professor, Department of Chemistry, University of South Florida, and Professor, Department of Community and Family Health, College of Public Health, University of South Florida. He completed his Ph.D. in Biochemistry from Louisiana State University in Baton Rouge. He was an NIH Post-Doctoral Fellow at the University of Alabama-Birmingham, College of Medicine in Nutritional Biochemistry. He then spent 19 years in medical education in Alabama and Oklahoma, being on the founding faculty of two medical schools and one dental school, including being Chair of Biochemistry and Associate Dean of Biomedical Sciences. He then served as Chair of the Department of Nutrition and Food Science at the University of Kentucky. Dr. Mercer has received numerous honors and awards, has over 140 articles in scientific publications and books, and memberships on editorial boards of professional journals. He has trained 65 students in his laboratory. For five years, he served the United Nations Third World Academy of Science as a Visiting Professor in Science and Sustainable Development to the Department of Nutrition, National Research Center, Giza, Dokki, Egypt. Dr. Mercer has spent 25 years in higher education administration and from 1999 to 2007, served as Campus Executive Officer for USF Polytechnic.

Area of Interest:

Chemistry
100%
Nutritional Biochemistry
62%
Clinical Chemistry
90%
Metabolism
75%
Physiochemical
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Robinson, E.N., L.P. Mercer, D. Saxon-Kelley, A. Tiu and A.U. Haq, 2005. The effect of sex on central histaminergic responses and corticosterone bioperiodicity in Sprague-Dawley rats. J. Nutr. Biochem., 16: 38-43.
    CrossRef  |  PubMed  |  Direct Link  |  
  2. Hassanien, M.H., L.A. Hussein, E.N. Robinson and L.P. Mercer, 2003. Human iodine requirements determined by the saturation kinetics model. J. Nutr. Biochem., 14: 280-287.
    CrossRef  |  PubMed  |  Direct Link  |  
  3. Mercer, L.P., D.S. Kelley, H.M. Bundrant, A.U. Haq, L.L. Humphries and W. Markesbery, 1998. Diet composition and sex influence bioperiodicity in rat's central nervous system histamine (H1) receptors. J. Nutr. Biochem., 9: 142-148.
    CrossRef  |  Direct Link  |  
  4. Mercer, L.P., 1997. Histamine and the neuroregulation of food intake. Nutrition, 13: 581-582.
    CrossRef  |  PubMed  |  Direct Link  |  
  5. Mercer, L.P., D.S. Kelley, H.M. Bundrant, A.U. Haq and L.L. Humphries, 1996. Gender affects rat's central nervous system histaminergic responses to dietary manipulation. J. Nutr., 126: 3128-3135.
    PubMed  |  Direct Link  |  
  6. Mercer, L.P., D.S. Kelley and L.L. Humphries, 1996. Dietary induced anorexia: A review of involvement of the histaminergic system. J. Am. Coll. Nutr., 15: 223-230.
    PubMed  |  Direct Link  |  
  7. Mercer, L.P. and D.S. Kelley, 1996. Analysis of bioperiodicity in physiological responses. Adv. Food Nutr. Res., 40: 217-226.
    PubMed  |  Direct Link  |  
  8. Haq, A.U., H.M. Bundrant and L.P. Mercer, 1996. Food intake is inversely correlated with central nervous system histamine receptor (H1) concentrations in male Sprague-Dawley rats fed normal, low protein, low energy or poor quality protein diets. J. Nutr., 126: 3083-3089.
    PubMed  |  Direct Link  |  
  9. Gorman, L., L.P. Mercer and B. Hennig, 1996. Growth requirements of endothelial cells in culture: Variations in serum and amino acid concentrations. Nutrition, 12: 266-270.
    PubMed  |  
  10. Mercer, L.P., D.S. Kelley, L.L. Humphries and J.D. Dunn, 1994. Manipulation of central nervous system histamine or histaminergic receptors (H1) affects food intake in rats. J. Nutr., 124: 1029-1036.
    PubMed  |  Direct Link  |  
  11. Mercer, L.P., S.J. Dodds and T.Y. Yi, 1993. The determination of nutritional requirements in rats: Variation with time of weight gain responses to indispensable amino acids. J. Nutr., 123: 964-971.
    PubMed  |  Direct Link  |  
  12. Mercer, L.P., M. Hidvegi and H. Hijazi, 1993. Weanling rats display bioperiodicity of growth rates and food intake rates. J. Nutr., 123: 1354-1362.
    PubMed  |  Direct Link  |  
  13. Mercer, L.P., 1991. The determination of nutritional requirements: Mathematical modeling of nutrient-response curves. J. Nutr., 122: 706-708.
    PubMed  |  Direct Link  |  
  14. Mercer, L.P., S.J. Dodds and J.D. Dunn, 1990. Histidine, histamine and the neuroregulation of food intake: A review and a hypothesis. Nutrition, 6: 273-277.
    PubMed  |  Direct Link  |  
  15. Rhee and L.P. Mercer, 1989. Biochemical Mechanisms of Dietary Amino Acids in Blood Pressure Regulation. In: New Horizons in Preventing Cardiovascular Diseases, Yamori, Y. and T. Strasser (Eds.), Elsevier Science Publishers, New York, USA., pp: 35-35.
  16. Mercer, L.P., S.J. Dodds, M.R. Schweisthal and J.D. Dunn, 1989. Brain histidine and food intake in rats fed single amino acid-deficient diets. J. Nutr., 119: 66-74.
    PubMed  |  Direct Link  |  
  17. Mercer, L.P., H.E. May and S.J. Dodds, 1989. The determination of nutritional requirements in rats: Mathematical modeling of sigmoidal, inhibited nutrient-response curves. J. Nutr., 119: 1465-1471.
    PubMed  |  Direct Link  |  
  18. Mercer, L.P., C.A. Gifford and S.J. Dodds, 1989. Histidine-Methionine Metabolic Interrelationships. In: Absorption and Utilization of Amino Acids, Friedman, M. (Ed.) Vol. 1, CRC Press, Boca Raton, pp: 189-198.
  19. Mercer, L.P. and S.J. Dodds, 1989. Dispensable-Indispensable Amino Acid Ratios in the Diet, In: Absorption and Utilization of Amino Acids, Friedman, M. (Ed.) Vol. 1, CRC Press, Boca Raton, pp: 1-13.
  20. Mercer, L.P., 1988. Letter to the editor. J. Nutr., 118: 918-918.
  21. Mercer, L.P. and S.J. Dodds, 1988. The Determination of Nutritional Requirements: A Mathematical Modeling Approach. In: Mathematical Modeling in Science and Technology, Rodin, E.Y. and X.J.R. Avula (Eds.) Vol. 11, Pergamon Press, New York, USA., pp: 1195-1200.
  22. Mercer, L.P., S.J. Dodds and D.L. Smith, 1987. A new method for formulation of amino acid concentrations and ratios in diets of rats. J. Nutr., 117: 1936-1944.
    PubMed  |  Direct Link  |  
  23. Mercer, L.P. and S.J. Dodds, 1987. The Saturation Kinetics Model. In: Mathematical Models in Experimental Nutrition, Canolty, N.L. and T.P. Cain (Eds.), Publication Services, University of Georgia, Athens, pp: 33-45.
  24. Karanja, N., J.A. Metz, L.P. Mercer and D.A. McCarron, 1987. Analysis of BP response and CA2+ metabolism using saturation kinetics model. Am. J. Physiol., 253: R501-R508.
    PubMed  |  ISI  |  
  25. Gifford, C.D., S.J. Dodds, L.K. Johnson, D.L. Smith and L.P. Mercer, 1987. Metabolic adaptation to protein deficiency in rats: Histidine. Nutr. Res., 7: 617-627.
    CrossRef  |  Direct Link  |  
  26. Dodds, S.J., P.L. Dornhofer, G.J. Frye and L.P. Mercer, 1987. Food intake and weight gain responses in dispensable, conditionally dispensable and indispensable amino acid deficiencies in rats. Nutr. Rep. Int., 35: 341-353.
  27. Rendell, M., J. Nierenberg, C. Brannan, J.L. Valentine and P.M. Stephen et al., 1986. The inhibition of glycation of albumin and hemoglobin by acetylation in vivo and in vitro. J. Lab. Clin. Med., 108: 286-293.
    PubMed  |  Direct Link  |  
  28. Mercer, L.P., J.M. Gustafson and S.J. Dodds, 1986. The determination of nutritional requirements: A modelling approach. Nutr. Rep. Int., 34: 337-350.
  29. Koo, S.I., S.J. Dodds and L.P. Mercer, 1986. Optimization of the dietary level of histidine in relation to the serum concentrations of zinc and copper in the weanling rat. Nutr. Res., 6: 967-979.
    CrossRef  |  Direct Link  |  
  30. Gustafson, J.M., R.F. Suda, S.J. Dodds, R.C. Burgus and L.P. Mercer, 1986. Brain and serum amino acid levels in rats fed graded levels of protein. J. Nutr., 116: 1667-1681.
  31. Mercer, L.P., J.M. Gustafson and S.J. Dodds, 1985. Protein Nutritional Quality: A Modelling Approach. In: Amino Acid Composition and Biological Value of Cereal Proteins, Lasztity, R. and M. Hidvegi (Eds.), Akademiai Kiado, Budapest, pp: 107-130.
  32. Mercer, L.P., J.M. Gustafson, P.T. Higbee, C.E. Geno M.R. Schweisthal and T.B. Cole, 1984. Control of physiological response in the rat by dietary nutrient concentration. J. Nutr., 114: 144-152.
    PubMed  |  Direct Link  |  
  33. Mercer, L.P. and J.M. Gustafson, 1984. A new protein quality evaluation index based on growth responses of rats. J. Nutr., 114: 911-919.
    PubMed  |  Direct Link  |  
  34. Gustafson, J.M., S.J. Dodds, J. Rudquist, J. Kelley, S. Ayers and L.P. Mercer, 1984. Food intake and weight gain responses to graded amino acid deficiencies in rats. Nutr. Rep. Int., 30: 1019-1026.
  35. Gustafson, J.M. and L.P. Mercer, 1984. Prediction of the toxicity of dietary cadmium by the four-parameter mathematical model for physiological responses. Nutr. Rep. Int., 29: 55-65.
  36. Carter, J.W. and L.P. Mercer, 1984. PCB-Induced hepatomegaly in rats as a function of dietary protein level. Nutr. Rep. Int., 30: 873-880.
    Direct Link  |  
  37. Carter, J.W. and L.P. Mercer, 1983. Prediction of food intake, weight gain and organ weights in rats as a function of dietary Aroclor 1254 (PCBs) by the saturation kinetics model for physiological responses. Nutr. Rep. Int., 27: 561-568.
  38. Carter, J.W. and L.P. Mercer, 1983. A pair-feeding study of PCB (Aroclor 1254) toxicity in rats. Bull. Environ. Contam. Toxicol., 31: 686-691.
    PubMed  |  Direct Link  |  
  39. Schweisthal, M.R., L.P. Mercer and T.B. Cole, 1982. Prediction of food intakes and weight gains in mature rats. Anat. Rec., 202: 131-136.
  40. Mercer, L.P., 1982. The quantitative nutrient-response relationship. J. Nutr., 112: 560-566.
    PubMed  |  Direct Link  |  
  41. Mercer, L.P. and S.S. Burkhardt, 1982. The relationship between food intake, weight gain and dietary nutrient concentration in the rat. Nutr. Rep. Int., 26: 121-129.
  42. Mercer, L.P. and S. Behr, 1982. A mathematical model for nutrition in toxicology. Nutr. Rep. Int., 26: 115-120.
  43. Burkhardt, S.S., L.P. Mercer, M.R. Schweisthal and T.B. Cole, 1982. The kinetics of specific weight gain and food intake in the rat. Am. J. Physiol., 243: R531-R536.
    PubMed  |  Direct Link  |  
  44. Mercer, L.P., M.R. Schweisthal and T.B. Cole, 1981. A quantitative study of maternal and fetal growth in rats by the four-parameter model for physiological responses. Nutr. Rep. Int., 24: 57-66.
  45. Gifford, J.M., L.P. Mercer and J.S. Ramlet, 1981. Prediction of relative brain weights and brain-free amino acid patterns in rats as a function of dietary protein. Nutr. Rep. Int., 24: 217-228.
    Direct Link  |  
  46. Mercer, L.P., and C.M. Baugh, 1978. Effect of Specific Nutrient Deficiencies in Man: Biotin. In: CRC Handbook of Nutrition and Food, Section E: Nutritional Disorders, Rechcigl, M. (Ed.). Vol. 3. CRC Press, Boca Raton, FL., USA., pp: 37-44.
  47. Mercer, L.P. and C.M. Baugh, 1974. The biosynthesis of riboflavin: Affinity chromatography purification of GTP ring-opening enzyme. Adv. Exp. Med. Biol., 42: 147-155.
    PubMed  |  Direct Link  |