Hi, I am Mark Stephen Kindy, My LiveDNA is 1.6059
 
   
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Dr. Mark Stephen Kindy
 
Highest Degree: Ph.D. in Biochemistry from Boston University School of Medicine, USA
 
Institute: Medical University of South Carolina, USA
 
Area of Interest: Biomedical Sciences
  •   Ischemia/Reperfusion Injury
  •   Gene Expression
  •   Amyloid Formation
  •   Alzheimer`s Disease
 
URL: http://livedna.org/1.6059
 
My SELECTED Publications
1:   Adibhatla, R.M., M.K. Baskaya, M.S. Kindy, M. Maley and R.J. Dempsey, 1997. Beneficial effects of Sadenosyl-L-methionine on blood-brain barrier breakdown and neuronal survival after transient cerebral ischemia in gerbils. Mol. Brain Res., 44: 134-138.
2:   Arancio, O., H.P. Zhang, X. Chen, C. Lin and F. Trinchese et al., 2004. RAGE potentiates Aβ-induced perturbation of neuronal function in transgenic mice. EMBO J., 23: 4096-4105.
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3:   Atkinson, C., H. Zhou, F. Qiao, J. Varela and J. Yu et al., 2006. Complement dependent P-selectin expression and injury following ischemic stroke. J. Immunol., 177: 7266-7274.
PubMed  |  
4:   Banka, C.L., T. Yuan, M.C. De Beer, M.S. Kindy, L.K. Curtiss and F.C. De Beer, 1995. Serum amyloid A (SAA): Influence on HDL-mediated cellular cholesterol efflux. J. Lipid Res., 36: 1058-1065.
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5:   Bhargava, N., M. Das, A.S. Karakoti, S. Patil and J.F. Kang et al., 2009. Regeneration of adult mice motoneurons utilizing a defined system and anti-oxidant nanoparticles. J. Nanoneurosci., 1: 130-143.
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6:   Bhat, N.R., K.F. Hauser and M.S. Kindy, 1992. Cell proliferation and protooncogene induction in oligodendroglial progenitors. J. Neurosci. Res., 32: 340-349.
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7:   Brown, K.E., M.S. Kindy and G.E. Sonenshein, 1992. Expression of the c-myb proto-oncogene in bovine vascular smooth muscle cells. J. Biol. Chem., 267: 4625-4630.
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8:   Bruce, A.J., W. Boling, M.S. Kindy, J. Peschon and P.J. Kraemer et al., 1996. Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors. Nat. Med., 2: 788-794.
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9:   Campos-Gonzalez, R. and M.S. Kindy, 1992. Tyrosine phosphorylation of microtubule‐associated protein kinase after transient ischemia in the gerbil brain. J. Neurochem., 59: 1955-1958.
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10:   Carney, J.M., J.P. Carney, B. Tolliver and M.S. Kindy, 1991. Selective effects of methamphetamine on mRNA expression and behavior in gerbils. J. Neuropharm., 30: 1011-1019.
11:   Chi, L., J. Yu, H. Zhu, X. Li and S. Zhu et al., 2010. Altered neuronal response to tumor necrosis factor-alpha in spinal cord injury. Neural Regenerat. Res., 5: 917-926.
12:   Chi, L.Y., J. Yu, H. Zhu, X.G. Li, S.G. Zhu and M.S. Kindy, 2008. The dual role of tumor necrosis factor-alpha in the pathophysiology of spinal cord injury. Neurosci. Lett., 438: 174-179.
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13:   Chudakova, D.A., Y.H. Zeidan, B.W. Wheeler, J. Yu and S.A. Novgorodov et al., 2008. Integrin-associated Lyn kinase promotes cell survival by suppressing acid sphingomyelinase activity. J. Biol. Chem., 283: 28806-28816.
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14:   Combs, D.J., R.J. Dempsey, D. Donaldson and M.S. Kindy, 1992. Hyperglycemia suppresses c-fos mRNA expression following transient cerebral ischemia in gerbils. J. Cerebral Blood Flow Metab., 12: 169-172.
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15:   De Beer, M.C., F.C. De Beer, W.D. McCubbin, C.M. Kay and M.S. Kindy, 1993. Structural prerequisites for amyloid fibril formation: A novel mouse model. J. Biol. Chem., 268: 20606-20612.
16:   De Beer, M.C., F.C. de Beer, C.J. Gerardot, D.R. Cecil, N.R. Webb, M.L. Goodson and M.S. Kindy, 1996. Structure of the mouse Saa4 gene and its linkage to the serum amyloid a gene family. Genomics, 34: 139-142.
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17:   De Beer, M.C., M.S. Kindy, W.S. Lane and F.C. De Beer, 1994. Mouse serum amyloid a protein (SAA5) structure and expression. J. Biol. Chem., 269: 4661-4667.
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18:   De Beer, M.C., T. Yuan, M.S. Kindy, B.F. Asztalos, P.S. Roheim and F.C. De Beer, 1995. Characterization of constitutive human serum amyloid A protein (SAA4) as an apolipoprotein. J. Lipid Res., 36: 526-534.
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19:   De Taboada, L., J. Yu, S. El-Amouri, J. Streeter and M.S. Kindy, 2011. Transcranial Laser Therapy (TLT) attenuates Aβ peptide neuropathology in APP transgenic mice. J. Alzheimers Dis., 23: 521-531.
20:   De Villiers, W.J., G.W. Varilek, F.C. de Beer, J.T. Guo and M.S. Kindy, 2000. Increased serum amyloid a levels reflect colitis severity and precede amyloid formation in IL-2 knockout mice. Cytokine, 12: 1337-1347.
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21:   Dean, M., R.A. Levine, W. Ran, M.S. Kindy, G.E. Sonenshein and J. Campisi, 1986. Regulation OFC-MYC transcription and mRNA abundance by serum growth factors and cell contact. J. Biol. Chem., 261: 9161-9166.
22:   Deane, R., S. Du Yan, R.K. Submamaryan, B. LaRue and S. Jovanovic et al., 2003. RAGE mediates amyloid-β peptide transport across the blood-brain barrier and accumulation in brain. Nat. Med., 9: 907-913.
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23:   Dempsey, R.J., J.M. Carney and M.S. Kindy, 1990. Inducible ornithine decarboxylase expression in brain subject to vasogenic oedema after transient ischaemia: Relationship to C-fos gene expression. Acta Neurochirurgica Supplementum, 51: 189-191.
PubMed  |  
24:   Dempsey, R.J., J.M. Carney and M.S. Kindy, 1991. Modulation of ornithine decarboxylase mRNA following transient ischemia in the gerbil brain. J. Cerebral Blood Flow Metab., 11: 979-985.
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25:   Dubal, D.B., H. Zhu, J. Yu, S.W. Rau and P.J. Shughrue et al., 2001. Estrogen receptor α, not β, is a critical link in estradiol-mediated protection against brain injury. Proc. Natl. Acad. Sci., 98: 1952-1957.
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26:   Dubal, D.B., S.W. Rau, P.J. Shughrue, H. Zhu and J. Yu et al., 2006. Differential modulation of estrogen receptors (ERs) in ischemic brain injury: A role for ER alpha in estradiol-mediated protection against delayed cell death. Endocrinology, 147: 3076-3084.
PubMed  |  
27:   El-Amouri, S.S., H. Zhu, J. Yu, F.H. Gage, I.M. Verma and M.S. Kindy, 2007. Neprilysin protects neurons against Aβ peptide toxicity. Brain Res., 1152: 191-200.
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28:   El-Amouri, S.S., H. Zhu, J. Yu, F.H. Gage, I.M. Verma and M.S. Kindy, 2008. Neprilysin: An enzyme candidate to slow the progression of Alzheimer's disease. Am. J. Pathol., 172: 1342-1354.
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29:   Ellis, B.C., S. Gattoni-Celli and M.S. Kindy, 2010. The impact of methylmercury on the vitamin D3-induced transcriptomic response in dolphin skin cells. Biol. Chem., 291: 245-258.
30:   Ellis, B.C., S. Gattoni-Celli, A. Mancia and M.S. Kindy, 2009. The vitamin D3 transcriptomic response in skin cells derived from the Atlantic bottlenose dolphin. Develop. Comp. Immunol., 33: 901-912.
PubMed  |  
31:   Ellsworth, J.L., R. Garcia, J. Yu and M.S. Kindy, 2003. Fibroblast growth factor-18 reduced infarct volumes and behavioral deficits after transient occlusion of the middle cerebral artery in rats. Stroke, 34: 1507-1512.
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32:   Ellsworth, J.L., R. Garcia, J. Yu and M.S. Kindy, 2004. Time window of fibroblast growth factor-18-mediated neuroprotection after occlusion of the middle cerebral artery in rats. J. Cerebral Blood Flow Metab., 24: 114-123.
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33:   Elvington, A., C. Atkinson, H. Zhu, J. Yu and K. Takahashi et al., 2012. Role of alternative and terminal complement pathways in propagating inflammation and injury following murine ischemic stroke. J. Immunol., 189: 4640-4647.
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34:   Elvington, A., C. Atkinson, L. Kulik, Z. Zhu and J. Yu et al., 2012. Pathogenic natural antibodies propagate cerebral injury following ischemic stroke in mice. J. Immunol., 188: 1460-1468.
PubMed  |  
35:   Ely, S., J.B. Ancsin, M.S. Kindy and R. Kisilevsky, 2001. Macrophage acyl-CoA: Cholesterol acyltransferase activity is influenced by the acute-phase apolipoprotein serum amyloid A. Amyloid, 8: 169-181.
36:   Ertekin-Taner, N., J. Ronald, L. Feuk, J. Prince and M. Tucker et al., 2005. Elevated amyloid {beta} protein (A{beta}42) and late onset Alzheimer's disease are associated with single nucleotide polymorphisms in the urokinase-type plasminogen activator gene. Human Mol. Genet., 14: 447-460.
PubMed  |  
37:   Estus, S., D. Borchelt, M.S. Kindy and R. Vassar, 2002. Abeta deposition is essential to AD neuropathology. J. Alzheimers Dis., 4: 133-138.
PubMed  |  
38:   Fanti, P., M.S. Kindy, S. Mohapatra, J. Klein, G. Colombo and H.H. Malluche, 2006. Dose-dependent effects of aluminum on osteocalcin synthesis in osteoblast-like ROS 17/2 cells in culture. Am. J. Physiol. Endocrinol. Metab., 263: E1113-E1118.
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39:   Garner, L.K., M. Mendelson, K.M. Albers, M.S. Kindy and B.M. Davis, 1994. The effects of activity on enkephalin and substance P mRNA in the developing chick spinal cord. J. Comp. Neurol., 347: 36-46.
40:   Garrett-Mayer, E., C. Wagner, B.W. Hollis, M.S. Kindy and S. Gattoni-Celli, 2012. Vitamin D3 supplementation (4000 IU per day for one year) eliminates differences in circulating 25(OH)D between African-American and Caucasian men. Am. J. Clin. Nutr., 96: 332-336.
PubMed  |  
41:   Gary, D.S., A.J. Bruce-Keller, M.S. Kindy and M.P. Mattson, 1998. Ischemic and excitotoxic brain injury is enhanced in mice lacking the p55 tumor necrosis factor receptor. J. Cerebral Blood Flow Metab., 18: 1283-1287.
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42:   Glenney, J.R., M.S. Kindy and L. Zokas, 1989. Isolation of a new member of the S100 protein family: Amino acid sequence, tissue and subcellular distribution. J. Cell Biol., 108: 569-578.
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43:   Govindaswami, M., S.A. Brown, J. Yu, H. Zhu, P.D. Bishop, M.S. Kindy and P.R. Oeltgen, 2008. Delta2 specific opioid receptor agonist and hibernating woodchuck plasma fraction provide ischemic neuroprotection. Acad. Emerg Med., 15: 250-257.
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44:   Guo, J.T., J. Yu, D. Grass, F.C. de Beer and M.S. Kindy, 2002. Inflammation-dependent cerebral deposition of serum amyloid a protein in a mouse model of amyloidosis. J. Neurosci., 22: 5900-5909.
45:   Guo, Z., M.S. Kindy, I. Kruman and M.P. Mattson, 2000. ALS-linked Cu/Zn-SOD mutation impairs cerebral synaptic glucose and glutamate transport and exacerbates ischemic brain injury. J. Cerebral Blood Flow Metab., 20: 463-468.
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46:   Heistand, D., B. Haley and M.S. Kindy, 1992. Phosphorylation changes following transient ischemia in the gerbil brain. J. Neurol. Sci., 113: 31-37.
47:   Hiestand, D.M. and M.S. Kindy, 1992. Calcium/calmodulin dependent protein kinase II mRNA in the gerbil brain after cerebral ischemia. Neurosci. Lett., 144: 75-78.
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48:   Hollis, B.W., D.T. Marshall, S.J. Savage, E. Garrett-Mayer, M.S. Kindy and S. Gattoni-Celli, 2013. Vitamin D3 supplementation, low-risk prostate cancer and health disparities. J. Steroid Biochem. Molec. Biol., 136: 233-237.
PubMed  |  
49:   Holtz, M.L., M.S. Kindy, S. Craddock, R.W. Moore and L.C. Pettigrew, 1996. Induction of PGH synthase and c-fos mRNA during early reperfusion of ischemic rat brain. Mol. Brain Res., 35: 339-343.
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50:   Hook, G., V. Hook and M.S. Kindy, 2011. The cysteine protease inhibitor, E64d, reduces brain amyloid-β and improves memory deficit in Alzheimer's disease animal models by inhibiting cathepsin B, but not BACE1, β-secretase activity. J. Alz. Dis., 26: 387-408.
PubMed  |  
51:   Hook, G., V.Y. Hook and M. Kindy, 2007. Cysteine protease inhibitors reduce brain beta-amyloid and beta-secretase activity in vivo and are potential Alzheimer's disease therapeutics. Biol. Chem., 388: 979-983.
PubMed  |  
52:   Hook, V., G. Hook and M.S. Kindy, 2010. Pharmacogenetic features of inhibitors to Cathepsin B that improve memory deficit and reduces beta-amyloid related to Alzheimers disease. Biol. Chem., 391: 861-872.
PubMed  |  
53:   Hook, V., L. Funkelstein, J. Wegrzyn, S. Bark, M. Kindy and G. Hook, 2011. Cysteine Cathepsins in the secretory vesicle produce active peptides: Cathepsin L generates peptide neurotransmitters and cathepsin B produces beta-amyloid of Alzheimers disease. Biochim. Biophys. Acta, 1824: 89-104.
CrossRef  |  PubMed  |  
54:   Hook, V., M. Kindy and G. Hook, 2007. Cysteine protease inhibitors effectively reduce in vivo levels of brain beta-amyloid related to Alzheimer's disease. Biol. Chem., 388: 247-252.
PubMed  |  
55:   Hook, V.Y., M. Kindy and G. Hook, 2008. Inhibitors of cathepsin B improve memory and reduce beta-amyloid in transgenic Alzheimer disease mice expressing the wild-type, but not the Swedish mutant, betasecretase site of the amyloid precursor protein. J. Biol. Chem., 283: 7745-7753.
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56:   Hook, V.Y., M. Kindy, T. Reinheckel, C. Peters and G. Hook, 2009. Genetic cathepsin B deficiency reduces betaamyloid in transgenic mice expressing human wild-type amyloid precursor protein. Biochem. Biophys. Res. Commun., 386: 284-288.
PubMed  |  
57:   Houdi, A.A., R. Dasgupta and M.S. Kindy, 1998. Effect of nicotine use and withdrawal on brain preproenkephalin A mRNA. Brain Res., 799: 257-263.
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58:   Hunter, C.L., O. Isacson, M. Nelson, H. Bimonte-Nelson and H. Seo et al., 2003. Regional alterations in amyloid precursor protein and nerve growth factor across age in a mouse model of Down's syndrome. Neurosci. Res., 45: 437-445.
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59:   Keller, J.N., C.M. Lauderback, D.A. Butterfield, M.S. Kindy, J. Yu and W.R. Markesbery, 2000. Potential role for apolipoprotein E in maintaining synaptic homeostasis. J. Neurochem., 74: 1579-1586.
60:   Keller, J.N., F.F. Huang, H. Zhu, J. Yu, Y.S. Ho and M.S. Kindy, 2000. Oxidative stress-associated impairment of proteasome activity during ischemia-reperfusion injury. J. Cerebral Blood Flow Metab., 20: 1467-1473.
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61:   Keller, J.N., K.B. Hanni and M.S. Kindy, 2000. Oxidized high-density lipoprotein induces neuron death. Exp. Neurol., 161: 621-630.
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62:   Keller, J.N., K.B. Hanni, S.P. Gabbita, V. Friebe, M.P. Mattson and M.S. Kindy, 1999. Oxidized lipoproteins increase reactive oxygen species formation in microglia and astrocyte cell lines. Brain Res., 830: 10-15.
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63:   Kindy, M.S. and D.J. Rader, 1998. Reduction in amyloid a amyloid formation in apolipoprotein-E-deficient mice. Am. J. Pathol., 152: 1387-1395.
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64:   Kindy, M.S. and G.E. Sonenshein, 1986. Regulation of oncogene expression in cultured aortic smooth muscle cells: Post-transcriptional control of c-myc mRNA. J. Biol. Chem., 261: 12865-12868.
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65:   Kindy, M.S. and I.M. Verma, 1990. Developmental expression of the Xenopus laevis fos protooncogene. Cell Growth Differ., 1: 27-37.
PubMed  |  
66:   Kindy, M.S., 1993. Inhibition of tyrosine phosphorylation prevents delayed neuronal death following cerebral ischemia. J. Cerebral Blood Flow Metab., 13: 372-377.
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67:   Kindy, M.S., 1994. NMDA receptor inhibition using antisense oligonucleotides prevents delayed neuronal death in gerbil hippocampus following cerebral-ischemia. Neurosci. Res. Commun., 14: 175-183.
68:   Kindy, M.S., A.N. Bhat and N.R. Bhat, 1992. Transient ischemia stimulates glial fibrillary acid protein and vimentin gene expression in the gerbil neocortex, striatum and hippocampus. Mol. Brain Res., 13: 199-206.
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69:   Kindy, M.S., A.R. King, G. Perry, M.C. de Beer, F.C. de Beer, 1995. Association of apolipoprotein E with murine AA amyloid. Lab. Invest., 73: 469-475.
70:   Kindy, M.S., A.R. King, J. Yu, C. Gerardot, J. Whitley and F.C. De Beer, 1998. Adenoviral expression of murine serum amyloid a proteins to study amyloid fibrillogenesis. Biochem. J., 332: 721-728.
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71:   Kindy, M.S., C.J. Chang and G.E. Sonenshein, 1988. Serum deprivation of vascular smooth muscle cells enhances collagen gene expression. J. Biol. Chem., 263: 11426-11430.
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72:   Kindy, M.S., F.C. De Beer, W.R. Marksbery, M. Pras and E. Pras et al., 1995. Apolipoprotein E isotypes in systemic amyloidoses. Amyloid, 2: 159-162.
73:   Kindy, M.S., J. Yu, J.T. Guo and H. Zhu, 1999. Apolipoprotein serum amyloid A in Alzheimer's disease. J. Alzheimer Dis., 1: 155-167.
74:   Kindy, M.S., J.E. McCormack, A.J. Buckler, R.A. Levine and G.E. Sonenshein, 1987. Independent regulation of transcription of the two strands of the c-myc gene. Mol. Cell. Biol., 7: 2857-2862.
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75:   Kindy, M.S., J.P. Carney, R.J. Dempsey and J.M. Carney, 1991. Ischemic induction of protooncogene expression in gerbil brain. J. Mol. Neurosci., 2: 217-228.
PubMed  |  
76:   Kindy, M.S., K.E. Brown and G.E. Sonenshein, 1991. Regulation of expression of the growth‐state‐related genes 2F1 and 2A9 during entry of quiescent smooth muscle cells into the cell cycle. J. Cell. Biochem., 46: 345-350.
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77:   Kindy, M.S., M. Srivatsan and B. Peretz, 1991. Age-related differential expression of neuropeptide mRNAs in Aplysia. Neuroreport, 2: 465-468.
78:   Kindy, M.S., M.C. de Beer, J. Yu and F.C. de Beer, 2000. Expression of mouse acute-phase (SAA1. 1) and constitutive (SAA4) serum amyloid A isotypes influence on lipoprotein profiles. Arteriosclerosis Thrombosis Vasc. Biol., 20: 1543-1550.
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79:   Kindy, M.S., Y. Hu and R.J. Dempsey, 1994. Blockade of ornithine decarboxylase enzyme protects against ischemic brain damage. J. Cerebral Blood Flow Metab., 14: 1040-1045.
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80:   Kirschner, D.A., R. Elliott-Bryant, K.E. Szumowski, W.A. Gonnerman, M.S. Kindy, J.D. Sipe and E.S. Cathcart, 1998. In vitro amyloid fibril formation by synthetic peptides corresponding to the amino terminus of apoSAA isoforms from amyloid-susceptible and amyloid-resistant mice. J. Struct. Biol., 124: 88-98.
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81:   Krishna, V., C. Lazaridis, D. Ellegala, S. Glazier, M. Kindy, M. Spampinato and J.A. Chalela, 2012. Spinal cord infarction associated with subarachnoid hemorrhage. Clin. Neurol. Neurosurgery, 114: 1030-1032.
PubMed  |  
82:   Krishna, V., S. Konakondla, J. Nicholas, A. Varma, M. Kindy and X. Wen, 2013. Biomaterial-based interventions for neuronal regeneration and functional recovery in rodent model of spinal cord injury: A systematic review. J. Spinal Cord Med., 36: 174-190.
PubMed  |  
83:   Kwon, B.K., J. Roy, J.H. Lee, E.B. Okon, H. Zhang, J.C. Marx and M.S. Kindy, 2009. Magnesium chloride in a polyethylene glycol formulation as a neuroprotective therapy for acute spinal cord injury: Preclinical refinement and optimization. J. Neurotrauma, 26: 1379-1393.
PubMed  |  
84:   Lauderback, C.M., J. Kanski, J.M. Hackett, N. Maeda, M.S. Kindy and D.A. Butterfield, 2002. Apolipoprotein E modulates Alzheimer's Aβ (1-42)-induced oxidative damage to synaptosomes in an allele-specific manner. Brain Res., 924: 90-97.
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85:   Lauderback, C.M., J.M. Hackett, J.N. Keller, S. Varadarajan and L. Szweda et al., 2001. Vulnerability of synaptosomes from ApoE knock-out mice to structural and oxidative modifications induced by Aβ(1-40):  Implications for Alzheimer's disease. Biochemistry, 40: 2548-2554.
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86:   Li, Y., T.A. Perry, M.S. Kindy, B.K. Harvey and D. Tweedie et al., 2009. GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism. Proc. Nat. Acad. Sci. USA., 106: 1285-1290.
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87:   Liao, F., A.J. Lusis, J.A. Berliner, A.M. Fogelman, M. Kindy, M.C. de Beer and F.C. de Beer, 1994. Serum amyloid A protein family. Differential induction by oxidized lipids in mouse strains. Arteriosclerosis Thromb. Vasc. Biol., 14: 1475-1479.
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88:   Mancia, A., M.L. Lundqvist, T.A. Romano, M.M. Peden-Adams and P.A. Fair et al., 2007. A dolphin peripheral blood leukocyte cDNA microarray for studies of immune function and stress reactions. Dev. Comp. Immunol., 31: 520-529.
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89:   Mann, J.S., M.S. Kindy, D.R. Edwards and T.E. Curry, 1991. Hormonal regulation of matrix metalloproteinase inhibitors in rat granulosa cells and ovaries. Endocrinology, 128: 1825-1832.
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90:   Mann, J.S., M.S. Kindy, J.F. Hyde, M.R. Clark and T.E. Curry, 1993. Role of protein synthesis, prostaglandins and estrogen in rat ovarian metalloproteinase inhibitor production. Biol. Reprod., 48: 1006-1013.
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91:   Marr, R.A., E. Rockenstein, A. Mukherjee, M.S. Kindy and L.B. Hersh et al., 2003. Neprilysin gene transfer reduces human amyloid pathology in transgenic mice. J. Neurosci., 23: 1992-1996.
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92:   Marr, R.A., H. Guan, E. Rockenstein, M. Kindy and F.H. Gage et al., 2004. Neprilysin regulates amyloid β peptide levels. J. Mol. Neurosci., 22: 5-11.
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93:   Marshall, D.T., S.J. Savage, E. Garrett-Mayer, T.E. Keane and B.W. Hollis et al., 2012. Vitamin D3 supplementation at 4,000 IU per day for one year correlates with a decrease of positive cores at repeat biopsy in subjects with low-risk prostate cancer under active surveillance. J. Clin. Endocrinol. Metabolism, 97: 2315-2324.
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94:   Marterre Jr., W.F., M.S. Kindy, J.M. Carney, R.W. Landrum and W.E. Strodel, 1991. Induction of the protooncogene c-fos and recovery of cytosolic adenosine triphosphate in reperfused liver after transient warm ischemia: Effect of nitrone free-radical spin-trap agents. Surgery, 110: 184-191.
PubMed  |  
95:   Mattson, M.P., H. Zhu, J. Yu and M.S. Kindy, 2000. Presenilin-1 mutation increases neuronal vulnerability to focal ischemia in vivo and to hypoxia and glucose deprivation in cell culture: Involvement of perturbed calcium homeostasis. J. Neurosci., 20: 1358-1364.
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96:   Mayeux, R., A.M. Saunders, S. Shea, S. Mirra and D. Evans et al., 1998. Utility of the apolipoprotein E genotype in the diagnosis of Alzheimer's disease. N. Engl. J. Med., 338: 506-511.
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97:   Moussaieff, A., J. Yu, H. Zhu, S. Gattoni-Celli, E. Shohami and M.S. Kindy, 2012. Protective effects of incensole acetate on cerebral ischemic injury. Brain Res., 1443: 89-97.
PubMed  |  
98:   Novgorodov, S.A., D.A. Chudakova, B.W. Wheeler, J. Bielawski, M.S. Kindy, L.M. Obeid and T.I. Gudz, 2011. Developmentally regulated ceramide synthase 6 increases mitochondrial Ca2+-loading capacity and promotes apoptosis. J. Biol. Chem., 286: 4644-4658.
99:   Osborne, J.G., M.S. Kindy and K.F. Hauser, 1991. Expression of proenkephalin mRNA in developing cerebellar cortex of the rat: Expression levels coincide with maturational gradients in Purkinje cells. Dev. Brain Res., 63: 63-69.
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100:   Osborne, J.G., M.S. Kindy, B.A. Spruce and K.F. Hauser, 1993. Ontogeny of proenkephalin mRNA and enkephalin peptide expression in the cerebellar cortex of the rat: spatial and temporal patterns of expression follow maturational gradients in the external granular layer and in Purkinje cells. Dev. Brain Res., 76: 1-12.
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101:   Pettigrew, L.C., M.L. Holtz, Y. Li, J. Yu and R.J. Kryscio et al., 2008. Focal cerebral ischemia in the TNFalpha-transgenic rat. J. Neuroinflammation, Vol. 5. 10.1186/1742-2094-5-47.
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102:   Pirlo, R.K., A.J. Sweeney, B.R. Ringeisen, M. Kindy and B.Z. Gao, 2011. Biochip/laser cell deposition system to assess polarized axonal growth from single neurons and neuron/glia pairs in microchannels with novel asymmetrical geometries. Biomicrofluidics, Vol. 30. .
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103:   Qiao, F., C. Atkinson, A. Shunmugavel, B.P. Morgan, M.S. Kindy, H. Song and S. Tomlinson, 2010. The alternative and terminal pathways of complement mediate post-traumatic spinal cord inflammation and injury. Am. J. Pathol., 177: 3061-3070.
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104:   Quinn, T.M., J.J. Taylor, J.A. Magarik, E. Vought, M.S. Kindy and D.B. Ellegala, 2011. Decompressive craniectomy: Technical note. Acta Neurol. Scand., 123: 239-244.
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105:   Ramanathan, S., J.C. Lewis, M.S. Kindy and S. Daunert, 1998. Heterogeneous bioluminescence binding assay for an octapeptide using recmobinant aequorin. Anal. Chim. Acta, 369: 181-188.
106:   Rao, A.M., J.F. Hatcher, M.S. Kindy and R.J. Dempsey, 1999. Arachidonic acid and leukotriene C4: Role in transient cerebral ischemia of gerbils. Neurochem. Res., 24: 1225-1232.
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107:   Rebeck, G.W., M. Kindy and M.J. LaDu, 2002. Apolipoprotein E and Alzheimer's disease: The protective effects of ApoE2 and E3. J. Alzheimer's Dis., 4: 145-154.
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108:   Reilly, C.F., M.S. Kindy, K.E. Brown, R.D. Rosenberg and G.E. Sonenshein, 1989. Heparin prevents vascular smooth muscle cell progression through the G1 phase of the cell cycle. J. Biol. Chem., 264: 6990-6995.
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109:   Sambamurti, K., A.C. Granholm, M.S. Kindy, N.R. Bhat, N.H. Greig, D.K. Lahiri and J.E. Mintzer, 2004. Cholesterol and Alzheimer's disease: Clinical and experimental models suggest interactions of different genetic, dietary and environmental risk factors. Curr. Drug Targets, 5: 517-528.
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110:   Sambamurti, K., N.H. Greig, T. Utsuki, E.L. Barnwell and E. Sharma et al., 2011. Targets for AD treatment: Conflicting messages from γ-secretase inhibitors. J. Neurochem., 117: 359-374.
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111:   Shaver, K.G., C.A. Blair, M.S. Kindy and Davis, 2012. Approaching the PSED: Some assembly required. J. Small Bus. Strategy, 22: 99-114.
112:   Smith, C.D., A.H. Andersen, R.J. Kryscio, F.A. Schmitt, M.S. Kindy, L.X. Blonder and M.J. Avison, 1999. Altered brain activation in cognitively intact individuals at high risk for Alzheimer's disease. Neurology, 53: 1391-1396.
113:   Smith, C.D., A.H. Andersen, R.J. Kryscio, F.A. Schmitt, M.S. Kindy, L.X. Blonder and M.J. Avison, 2001. Differences in functional magnetic resonance imaging activation by category in a visual confrontation naming task. J. Neuroimaging, 11: 165-170.
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114:   Smith, C.D., A.H. Andersen, R.J. Kryscio, F.A. Schmitt, M.S. Kindy, L.X. Blonder and M.J. Avison, 2002. Women at risk for AD show increased parietal activation during a fluency task. Neurology, 58: 1197-1202.
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115:   Soto, C., M.S. Kindy, M. Baumann and B. Frangione, 1996. Inhibition of Alzheimer's amyloidosis by peptides that prevent beta-sheet conformation. Biochem. Biophys. Res. Commun., 226: 672-680.
116:   Stepp, M.A., M. Kindy, C. Franzblau and G. Sonenshein, 1985. Cloning of type III collagen and expression in aortic smooth muscle cells. Ann. N. Y. Acad. of Sci., 460: 510-513.
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117:   Stepp, M.A., M.S. Kindy, C. Franzblau and G.E. Sonenshein, 1986. Complex regulation of collagen gene expression in cultured bovine aortic smooth muscle cells. J. Biol. Chem., 261: 6542-6547.
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118:   Suzuki, S., L.M. Gerhold, M. Bottner, S.W. Rau and C. Dela Cruz et al., 2007. Estradiol enhances neurogenesis following ischemic stroke through estrogen receptors α and β. J. Comp. Neurol., 500: 1064-1075.
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119:   Thirumangalakudi, L., A. Prakasam, R. Zhang, H. Bimonte-Nelson, K. Sambamurti, M.S. Kindy and N.R. Bhat, 2008. High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice. J. Neurochem., 106: 475-485.
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120:   Varghese, K., P. Molnar, M. Das, N. Bhargava, S. Lambert, M. Kindy and J.J. Hickman, 2010. A new target for amyloid beta toxicity validated by standard and high-throughput electrophysiology. PLoS Biol., Vol. 5. 10.1371/journal.pone.0008643.
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121:   Varghese, K., P. Molnar, M. Stancescu, M. Das, N. Bhargava, M.S. Kindy and J.J. Hickman, 2009. Regeneration and characterization of adult mouse hippocampal neurons in a defined in vitro system. J. Neurosci. Methods, 177: 51-59.
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122:   Vest, R.S., H. O'Leary, M.S. Kindy and K.U. Bayer, 2010. Effective post-insult neuroprotection by a novel CaMKII inhibitor. J. Biol. Chem., 285: 20675-20682.
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123:   Wang, Y., A. Meng, H. Lang, S.A. Brown and J.L. Konopa et al., 2004. Activation of nuclear factor kappaB In vivo selectively protects the murine small intestine against ionizing radiation-induced damage. Cancer Res., 64: 6240-6246.
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124:   Webb, N.R., L. Cai, K.S. Ziemba, J. Yu, M.S. Kindy, D.R. van der Westhuyzen and F.C. de Beer, 2002. The fate of HDL particles in vivo after SR-BI-mediated selective lipid uptake. J. Lipid Res., 43: 1890-1898.
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125:   Webb, N.R., M.C. De Beer, D.R. Van der Westhuyzen, M.S. Kindy and C.L. Banka et al., 1997. Adenoviral vector-mediated overexpression of serum amyloid A in apoA-I-deficient mice. J. Lipid Res., 38: 1583-1590.
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126:   Webb, N.R., M.C. de Beer, J. Yu, M.S. Kindy, A. Daugherty, D.R. van der Westhuyzen and F.C. de Beer, 2002. Overexpression of SR-BI by adenoviral vector promotes clearance of apoA-I, but not apoB, in human apoB transgenic mice. J. Lipid Res., 43: 1421-1428.
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127:   Witkowski, A., S. Daunert, M.S. Kindy and L.G. Bachas, 1993. Enzyme-linked immunosorbent assay for an octapeptide based on a genetically engineered fusion protein. Anal. Chem., 65: 1147-1151.
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128:   Wu, J., B.B. Zhu, J. Yu, H. Zhu and L. Qiu et al., 2003. In vitro and in vivo modulations of benzo [c] phenanthrene-DNA adducts by DNA mismatch repair system. Nucleic Acids Res., 31: 6428-6434.
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129:   Wyss-Coray, T., L. McConlogue, M. Kindy, A.M. Schmidt, S. Du Yan and D.M. Stern, 2001. Key signaling pathways regulate the biological activities and accumulation of amyloid-β. Neurobiol. Aging, 22: 967-973.
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130:   Xie, C., M.A. Lovell, S. Xiong, M.S. Kindy and J.T. Guo et al., 2001. Expression of glutathione-S-transferase isozyme in the SY5Y neuroblastoma cell line increases resistance to oxidative stress. Free Radic. Biol. Med., 31: 73-81.
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131:   Yan, S.D., H. Zhu, A. Zhu, A. Golabek and B. Wolozin et al., 2000. RAGE and amyloid fibrils: Receptor-dependent signaling by beta-sheet fibrils mediates cellular stress in amyloidosis. Nat. Med., 6: 643-651.
132:   Yu, J., H. Zhu, D. Ko and M.S. Kindy, 2008. Motoneuronotrophic factor analog GM6 reduces infarct volume and behavioral deficits following transient ischemia in the mouse. Brain Res., 1238: 143-153.
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133:   Yu, J., H. Zhu, J.T. Guo, F.C. de Beer and M.S. Kindy, 2000. Expression of mouse apolipoprotein SAA1. 1 in CE/J mice: Isoform-specific effects on amyloidogenesis. Lab. Invest., 80: 1797-1806.
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134:   Yu, J., J.T. Guo, H. Zhu and M.S. Kindy, 2000. Amyloid formation in the rat: Adenoviral expression of mouse serum amyloid A proteins. Amyloid, 7: 32-40.
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135:   Yu, J., M. Gattoni-Celli, H. Zhu, N.R. Bhat, K. Sambamurti, S. Gattoni-Celli and M.S. Kindy, 2011. Vitamin D3-Enriched diet correlates with a decrease of amyloid plaques in the brain of APP transgenic mice. J. Alz. Disease, 25: 295-307.
136:   Yu, J., M.S. Kindy and S. Gattoni-Celli, 2007. Semi-allogeneic vaccine for T-cell lymphoma. J. Trans. Med., Vol. 5. 10.1186/1479-5876-5-39.
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137:   Yu, J., M.S. Kindy, B.C. Ellis, J.E. Baatz and M. Peden-Adams et al., 2005. Establishment of epidermal cell lines derived from the skin of the atlantic bottlenose dolphin (Tursiops Truncatus). Anat Rec A Discov Mol. Cell Evol. Biol., 287: 1246-1255.
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138:   Yu, J., S.A. Novgorodov, D. Chudakova, H. Zhu and A. Bielawska et al., 2007. JNK3 signaling pathway activates ceramide synthase leading to mitochondrial dysfunction. J. Biol. Chem., 282: 25940-25949.
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139:   Yu, Z., D. Zhou, A.J. Bruce-Keller, M.S. Kindy and M.P. Mattson, 1999. Lack of the p50 subunit of nuclear factor-kappaB increases the vulnerability of hippocampal neurons to excitotoxic injury. J. Neurosci., 19: 8856-8865.
140:   Yun, X., V. Maximov, J. Yu, H. Zhu, A. Vertegel and M.S. Kindy, 2013. Nanoparticles for targeted delivery of antioxidant enzymes to the brain following cerebral ischemia and reperfusion injury. J. Cereb. Blood Flow Metab., 34: 583-592.
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141:   Zhang, L., J. Yu and M. Kindy, 2005. Does knockout of JNK3 gene provide a protective action in spinal cord injury of mice? Int. J. Emergency Critical Care Med., 2: 497-503.
142:   Zhang, W., H. Li, Z. Xing, H. Yuan, M.S. Kindy and Z.Z. Li, 2012. Expression of mRNAs for PPT, CGRP, NF-200, and MAP-2 in cocultures of dissociated DRG neurons and skeletal muscle cells in administration of NGF or NT-3. Folia Histochemica Cytobiologica, 50: 312-318.
143:   Zhu, H., J. Yu and M.S. Kindy, 2001. Inhibition of amyloidosis using low-molecular-weight heparins. Mol. Med., 7: 517-522.
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