Dr. J. Michael Mathis

Dr. J. Michael Mathis

Head of Academic Department/Faculty
LSU School of Veterinary Medicine, USA


Highest Degree
Ph.D. in Biochemistry from Louisiana State University, USA

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Area of Interest:

Chemistry
100%
Biochemistry
62%
Biophysics
90%
Endocrinology
75%
Oncology
55%

Education

1997

Ph.D.

Louisiana State University, USA

Biochemistry

Selected Publications

  1. Williams, B.J., S. Bhatia, L.K. Adams, S. Boling and J.L. Carroll et al., 2012. Dendritic cell based PSMA immunotherapy for prostate cancer using a CD40-targeted adenovirus vector. PloS One, Vol. 7. 10.1371/journal.pone.0046981.
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  2. Toomey, J.S., S. Bhatia, T.M. La'Wanda, E.A. Orchard and K.H. Tainter et al., 2012. PET imaging a MPTP-induced mouse model of Parkinson's disease using the fluoropropyl-dihydrotetrabenazine analog [18F]-DTBZ (AV-133). PloS One, Vol. 7. 10.1371/journal.pone.0039041.
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  3. Chu, Q.D., G. Sun, M. Pope, N. Luraguiz and D.T. Curiel et al., 2012. Virotherapy using a novel chimeric oncolytic adenovirus prolongs survival in a human pancreatic cancer xenograft model. Surgery, 152: 441-448.
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  4. Chaitanya, G.V., W. Cromer, S. Wells, M. Jennings, J.M. Mathis, A. Minagar and J.S. Alexander, 2012. Metabolic modulation of cytokine-induced brain endothelial adhesion molecule expression. Microcirculation, 19: 155-165.
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  5. Batra, V., Z. Syed, J.N. Gill, M.A. Coburn and P. Adegboyega et al., 2012. Effects of the tropical ginger compound,1'-acetoxychavicol acetate, against tumor promotion in K5.Stat3C transgenic mice. J. Exp. Clin. Cancer Res., 31: 57-57.
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  6. Mathis, J.M., S. Bhatia, A. Khandelwal, I. Kovesdi and S.J. Lokitz et al., 2011. Genetic incorporation of human metallothionein into the adenovirus protein IX for non-invasive SPECT imaging. PloS One, Vol. 6. 10.1371/journal.pone.0016792.
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  7. Cromer, W.E., J.M. Mathis, D.N. Granger, G.V. Chaitanya and J.S. Alexander, 2011. Role of the endothelium in inflammatory bowel diseases. World J. Gastroenterol., 17: 578-593.
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  8. Coburn, M.A., S. Brueggemann, S. Bhatia, B. Cheng and B.D. Li et al., 2011. Establishment of a mammary carcinoma cell line from Syrian hamsters treated with N-methyl-N-nitrosourea. Cancer Lett., 312: 82-90.
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  9. Chaitanya, G.V., W.E. Cromer, S.R. Wells, M.H. Jennings and P.O. Couraud et al., 2011. Gliovascular and cytokine interactions modulate brain endothelial barrier in vitro. J. Neuroinflammation, Vol. 8. 10.1186/1742-2094-8-162.
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  10. Veluswamy, H., K. Suryawala, A. Sheth, S. Wells and E. Salvatierra et al., 2010. African-American inflammatory bowel disease in a Southern U.S. health center. BMC Gastroenterol., Vol. 10. 10.1186/1471-230X-10-104.
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  11. Short, J.J., A.A. Rivera, H. Wu, M.R. Walter, M. Yamamoto, J.M. Mathis and D.T. Curiel, 2010. Substitution of adenovirus serotype 3 hexon onto a serotype 5 oncolytic adenovirus reduces factor X binding, decreases liver tropism, and improves antitumor efficacy. Mol. Cancer Therapeutics, 9: 2536-2544.
    CrossRef  |  PubMed  |  Direct Link  |  

  12. Pennington, K., Q.D. Chu, D.T. Curiel, B.D. Li and J.M. Mathis, 2010. The utility of a tissue slice model system to determine breast cancer infectivity by oncolytic adenoviruses. J. Surgical Res., 163: 270-275.
    CrossRef  |  PubMed  |  Direct Link  |  

  13. Kleiner-Hancock, H.E., R. Shi, A. Remeika, D. Robbins and M. Prince et al., 2010. Effects of ATRA combined with citrus and ginger-derived compounds in human SCC xenografts. BMC Cancer, Vol. 10. 10.1186/1471-2407-10-394.
    CrossRef  |  PubMed  |  Direct Link  |  

  14. Ganta, V.C., W. Cromer, G.L. Mills, J. Traylor and M. Jennings et al., 2010. Angiopoietin-2 in experimental colitis. Inflammatory Bowel Dis., 16: 1029-1039.
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  15. Davis, J.N., D. Rogers, L. Adams, T. Yong and J.S. Jung et al., 2010. Association of core-binding factor β with the malignant phenotype of prostate and ovarian cancer cells. J. Cellular Physiol., 225: 875-887.
    CrossRef  |  PubMed  |  Direct Link  |  

  16. Cromer, W., M.H. Jennings, Y. Odaka, J. Michael Mathis and J. Steven Alexander, 2010. Murine rVEGF164b, an Inhibitory VEGF reduces VEGF-A-dependent endothelial proliferation and barrier dysfunction. Microcirculation, 17: 536-547.
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  17. Chaitanya, G.V., S.E. Franks, W. Cromer, S.R. Wells and M. Bienkowska et al., 2010. Differential cytokine responses in human and mouse lymphatic endothelial cells to cytokines in vitro. Lymphatic Res. Biol., 8: 155-164.
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  18. Becks, L., M. Prince, H. Burson, C. Christophe and M. Broadway et al., 2010. Aggressive mammary carcinoma progression in Nrf2 knockout mice treated with 7,12-dimethylbenz[a]anthracene. BMC Cancer, Vol. 10. 10.1186/1471-2407-10-540.
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  19. Balyasnikova, I.V., R. Franco‐Gou, J.M. Mathis and M.S. Lesniak, 2010. Genetic modification of mesenchymal stem cells to express a single-chain antibody against EGFRvIII on the cell surface. J. Tissue Eng. Regenerative Med., 4: 247-258.
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  20. Stoff, A., A.A. Rivera, N. Sanjib Banerjee, S.T. Moore and T. Michael Numnum et al., 2009. Promotion of incisional wound repair by human mesenchymal stem cell transplantation. Exp. Dermatol., 18: 362-369.
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  21. Li, X.L., Y.Y. Liu, D. Knight, Y. Odaka and J.M. Mathis et al., 2009. Effect of B7.1 costimulation on T-cell based immunity against TAP-negative cancer can be facilitated by TAP1 expression. PloS One, Vol. 4. 10.1371/journal.pone.0006385.
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  22. Li, X.L., D. Zhang, D. Knight, Y. Odaka, J. Glass, J.M. Mathis and Q.J. Zhang, 2009. Priming of immune responses against transporter associated with antigen processing (TAP)‐deficient tumours: Tumour direct priming. Immunology, 128: 420-428.
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  23. Kleiner, H.E., P. Krishnan, J. Tubbs, M. Smith and C. Meschonat et al., 2009. Tissue microarray analysis of eIF4E and its downstream effector proteins in human breast cancer. J. Exp. Clin. Cancer Res., 28: 54-54.
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  24. Zhang, Q.J., X.L. Li, D. Wang, X.C. Huang and J.M. Mathis et al., 2008. Trogocytosis of MHC-I/peptide complexes derived from tumors and infected cells enhances dendritic cell cross-priming and promotes adaptive T cell responses. PloS One, Vol. 3. 10.1371/journal.pone.0003097.
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  25. Stoff-Khalili, M.A., A.A. Rivera, A. Nedeljkovic-Kurepa, A. DeBenedetti and X.L. Li et al., 2008. Cancer-specific targeting of a conditionally replicative adenovirus using mRNA translational control. Breast Cancer Rese. Treatment, 108: 43-55.
    CrossRef  |  PubMed  |  Direct Link  |  

  26. Sonabend, A.M., I.V. Ulasov, M.A. Tyler, A.A. Rivera, J.M. Mathis and M.S. Lesniak, 2008. Mesenchymal stem cells effectively deliver an oncolytic adenovirus to intracranial glioma. Stem Cells, 26: 831-841.
    CrossRef  |  PubMed  |  Direct Link  |  

  27. Siegele, B., C. Cefalu, N. Holm, G. Sun and J. Tubbs et al., 2008. eIF4E-targeted suicide gene therapy in a minimal residual mouse model for metastatic soft-tissue head and neck squamous cell carcinoma improves disease-free survival. J. Surgical Res., 148: 83-89.
    CrossRef  |  PubMed  |  Direct Link  |  

  28. Li, X.L., D.Q. Zhang, D. Wang, D.S. Knight and L. Yin et al., 2008. In vivo survivors of transformed mouse ovarian surface epithelial cells display diverse phenotypes for gene expression and tumorigenicity. Tumor Biol., 29: 359-370.
    CrossRef  |  PubMed  |  Direct Link  |  

  29. Zhu, Z.B., J.M. Mathis, S.K. Makhija, B. Lu and M. Wang et al., 2007. Targeting of a conditionally replicative adenovirus agent to human squamous cell carcinomas of the head and neck. Int. J. Oncol., 31: 1213-1222.
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  30. Ulasov, I.V., A.A. Rivera, D.M. Nettelbeck, L.B. Rivera and J.M. Mathis et al., 2007. An oncolytic adenoviral vector carrying the tyrosinase promoter for glioma gene therapy. Int. J. Oncol., 31: 1177-1185.
    CrossRef  |  PubMed  |  Direct Link  |  

  31. Stoff-Khalili, M.A., A.A. Rivera, J.M. Mathis, N.S. Banerjee and A.S. Moon et al., 2007. Mesenchymal stem cells as a vehicle for targeted delivery of CRAds to lung metastases of breast carcinoma. Breast Cancer Res. Treatment, 105: 157-167.
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  32. Stoff, A., A.A. Rivera, J.M. Mathis, S.T. Moore and N.S. Banerjee et al., 2007. Effect of adenoviral mediated overexpression of fibromodulin on human dermal fibroblasts and scar formation in full-thickness incisional wounds. J. Mol. Med., 85: 481-496.
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  33. Stoff‐Khalili, M.A., A.A. Rivera, A. Stoff, J.M. Mathis and R.P. Rocconi et al., 2007. Combining high selectivity of replication via CXCR4 promoter with fiber chimerism for effective adenoviral oncolysis in breast cancer. Int. J. Cancer, 120: 935-941.
    CrossRef  |  PubMed  |  Direct Link  |  

  34. Jiang, B., V.Y. Hebert, Y. Li, J.M. Mathis, J.S. Alexander and T.R. Dugas, 2007. HIV antiretroviral drug combination induces endothelial mitochondrial dysfunction and reactive oxygen species production, but not apoptosis. Toxicol. Applied Pharmacol., 224: 60-71.
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  35. Holm, N.T., K. Byrnes, B.D. Li, R.H. Turnage, F. Abreo, J.M. Mathis and Q.D. Chu, 2007. Elevated levels of chemokine receptor CXCR4 in HER-2 negative breast cancer specimens predict recurrence. J. Surgical Res., 141: 53-59.
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  36. Chu, Q.D., L. Sun, J. Li, K. Byrnes and D. Chervenak et al., 2007. Rat adenocarcinoma cell line infected with an adenovirus carrying a novel herpes-simplex virus-thymidine kinase suicide gene construct dies by apoptosis upon treatment with ganciclovir. J. Surgical Res., 143: 189-194.
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  37. Byrnes, K., B.D. Li, N. Holm, J. Li and Y. Okadata et al., 2007. A novel suicide gene therapy targeting the overexpression of eukaryotic initiation factor 4E improves survival in a rat peritoneal carcinomatosis model. Surgery, 142: 270-275.
    CrossRef  |  PubMed  |  Direct Link  |  

  38. Alexander, J.S., J.M. Mathis and K. Pruitt, 2007. Interaction of microsatellite instability and loss of heterozygosity in adenocarcinoma: Multiple markers in adenocarcinoma: An introduction to 'Genetic changes in Slovenian patients with gastric adenocarcinoma evaluated in terms of microsatellite DNA'. Eur. J. Gastroenterol. Hepatol., 19: 1038-1040.
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  39. Strat, A., L. Gao, T. Utsuki, B. Cheng and S. Nuthalapaty et al., 2006. Specific and nontoxic silencing in mammalian cells with expressed long dsRNAs. Nucleic Acids Res., 34: 3803-3810.
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  40. Stoff-Khalili, M.A., A.A. Rivera, L.P. Le, A. Stoff and M. Everts et al., 2006. Employment of liver tissue slice analysis to assay hepatotoxicity linked to replicative and nonreplicative adenoviral agents. Cancer Gene Therapy, 13: 606-618.
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  41. Stoff, A., A.A. Rivera, N.S. Banerjee, J. Michael Mathis, A. Espinosa‐de‐los‐Monteros et al., 2006. Strategies to enhance transductional efficiency of adenoviral-based gene transfer to primary human fibroblasts and keratinocytes as a platform in dermal wounds. Wound Repair Regeneration, 14: 608-617.
    CrossRef  |  PubMed  |  Direct Link  |  

  42. Matthews, Q.L., D.A. Sibley, H. Wu, J. Li and M.A. Stoff-Khalili et al., 2006. Genetic incorporation of a herpes simplex virus type 1 thymidine kinase and firefly luciferase fusion into the adenovirus protein IX for functional display on the virion. Mol. Imag., 5: 510-519.
    PubMed  |  

  43. Mathis, J.M., P.L. Stewart, Z.B. Zhu and D.T. Curiel, 2006. Advanced generation adenoviral virotherapy agents embody enhanced potency based upon CAR-independent tropism. Clin. Cancer Res., 12: 2651-2656.
    CrossRef  |  PubMed  |  Direct Link  |  

  44. Mathis, J.M., B.J. Williams, D.A. Sibley, J.L. Carroll and J. Li et al., 2006. Cancer-specific targeting of an adenovirus-delivered herpes simplex virus thymidine kinase suicide gene using translational control. J. Gene Med., 8: 1105-1120.
    CrossRef  |  PubMed  |  Direct Link  |  

  45. Stoff-Khalili, M.A., A.A. Rivera, J.N. Glasgow, L.P. Le and A. Stoff et al., 2005. A human adenoviral vector with a chimeric fiber from canine adenovirus type 1 results in novel expanded tropism for cancer gene therapy. Gene Therapy, 12: 1696-1706.
    CrossRef  |  PubMed  |  Direct Link  |  

  46. Stoff-Khalili, M.A., A. Stoff, A.A. Rivera, N.S. Banerjee and M. Everts et al., 2005. Preclinical evaluation of transcriptional targeting strategies for carcinoma of the breast in a tissue slice model system. Breast Cancer Res., 7: R1141-R1152.
    CrossRef  |  PubMed  |  Direct Link  |  

  47. Stoff-Khalili, M.A., A. Stoff, A.A. Rivera, J.M. Mathis and M. Everts et al., 2005. Gene transfer to carcinoma of the breast with fiber-modified adenoviral vectors in a tissue slice model system. Cancer Boil. Therapy, 4: 1203-1210.
    CrossRef  |  PubMed  |  Direct Link  |  

  48. Sasaki, M., J.M. Mathis, M.H. Jennings, P. Jordan and Y. Wang et al., 2005. Reversal of experimental colitis disease activity in mice following administration of an adenoviral IL-10 vector. J. Inflammation, Vol. 2. 10.1186/1476-9255-2-13.
    CrossRef  |  PubMed  |  Direct Link  |  

  49. Mathis, J.M., M.A. Stoff-Khalili and D.T. Curiel, 2005. Oncolytic adenoviruses-selective retargeting to tumor cells. Oncogene, 24: 7775-7791.
    CrossRef  |  Direct Link  |  

  50. Mathis, J.M. and A. DeBenedetti, 2005. Control of protein translation in cancer therapy. Sci. Med., 10: 74-77.

  51. Li, J., L. Le, D.A. Sibley, J.M. Mathis and D.T. Curiel, 2005. Genetic incorporation of HSV-1 thymidine kinase into the adenovirus protein IX for functional display on the virion. Virology, 338: 247-258.
    CrossRef  |  PubMed  |  Direct Link  |  

  52. Pezzi, V., J.M. Mathis, W.E. Rainey and B.R. Carr, 2003. Profiling transcript levels for steroidogenic enzymes in fetal tissues. J. Steroid Biochem. Mol. Boil., 87: 181-189.
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  53. Kolomytkin, O.V., A.A. Marino, D.D. Waddell, J.M. Mathis, R.E. Wolf, K.K. Sadasivan and J.A. Albright, 2002. IL-1β-induced production of metalloproteinases by synovial cells depends on gap junction conductance. Am. J. Physiol. Cell. Physiol., 282: 1254-1260.
    CrossRef  |  PubMed  |  Direct Link  |  

  54. Fallo, F., V. Pezzi, L. Barzon, P. Mulatero, F. Veglio, N. Sonino and J.M. Mathis, 2002. Quantitative assessment of CYP11B1 and CYP11B2 expression in aldosterone-producing adenomas. Eur. J. Endocrinol., 147: 795-802.
    CrossRef  |  PubMed  |  Direct Link  |  

  55. Virmani, A.K., C. Muller, A. Rathi, S. Zoechbauer-Mueller, M. Mathis and A.F. Gazdar, 2001. Aberrant methylation during cervical carcinogenesis. Clin. Cancer Res., 7: 584-589.
    PubMed  |  Direct Link  |  

  56. Carroll, J.L., L.L. Nielsen, S.B. Pruett and J.M. Mathis, 2001. The role of natural killer cells in adenovirus-mediated p53 gene therapy. Mol. Cancer Ther., 1: 49-60.
    PubMed  |  Direct Link  |  

  57. Bell, M.C., S.A. Davidson, J.M. Mathis and F. Ampil, 2001. Topotecan concomitant with primary brachytherapy radiation in patients with cervical carcinoma: A phase I trial. Gynecol. Oncol., 80: 128-131.
    CrossRef  |  PubMed  |  Direct Link  |  

  58. Nielsen, L.L., M. Gurnani, B. Shi, G. Terracina and R.C. Johnson et al., 2000. Derivation and initial characterization of a mouse mammary tumor cell line carrying the polyomavirus middle T antigen: Utility in the development of novel cancer therapeutics. Cancer Res., 60: 7066-7074.
    PubMed  |  Direct Link  |  

  59. Bell, M.C., P. Crowley-Nowick, H.L. Bradlow, D.W. Sepkovic and D. Schmidt-Grimminger et al., 2000. Placebo-controlled trial of indole-3-carbinol in the treatment of CIN. Gynecol. Oncol., 78: 123-129.
    CrossRef  |  PubMed  |  Direct Link  |  

  60. Von Gruenigen, V.E., J.D. O'boyle, R.L. Coleman, D. Wilson, D.S. Miller and J.M. Mathis, 1999. Efficacy of intraperitoneal adenovirus-mediated p53 gene therapy in ovarian cancer. Int. J. Gynecol. Cancer, 9: 365-372.
    CrossRef  |  PubMed  |  Direct Link  |  

  61. Lavranos, T.C., J.M. Mathis, S.E. Latham, B. Kalionis, J.W. Shay and R.J. Rodgers, 1999. Evidence for ovarian granulosa stem cells: Telomerase activity and localization of the telomerase ribonucleic acid component in bovine ovarian follicles. Biol. Reproduction, 61: 358-366.
    CrossRef  |  PubMed  |  Direct Link  |  

  62. Von Gruenigen, V.E., J.T. Santoso, R.L. Coleman, C.Y. Muller, D.S. Miller and J.M. Mathis, 1998. In Vivo studies of adenovirus-based p53 gene therapy for ovarian cancer. Gynecol. Oncol., 69: 197-204.
    CrossRef  |  PubMed  |  Direct Link  |  

  63. Thai, T.H., F. Du, J.T. Tsan, Y. Jin and A. Phung et al., 1998. Mutations in the BRCAI-Associated RING Domain (BARD1) gene in primary breast, ovarian and uterine cancers. Human Mol. Genet., 7: 195-202.
    CrossRef  |  PubMed  |  Direct Link  |  

  64. Santoso, J.T., J.A. Lucci, R.L. Coleman, S. Hatch, P. Wong, D. Miller and J.M. Mathis, 1998. Does glutamine supplementation increase radioresistance in squamous cell carcinoma of the cervix? Gynecol. Oncol., 71: 359-363.
    CrossRef  |  PubMed  |  Direct Link  |  

  65. Pezzi, V., C.D. Clyne, S. Ando, J.M. Mathis and W.E. Rainey, 1997. Ca2+-regulated expression of aldosterone synthase is mediated by calmodulin and calmodulin-dependent protein kinases. Endocrinology, 138: 835-838.
    CrossRef  |  PubMed  |  Direct Link  |  

  66. Clyne, C.D., Y. Zhang, L. Slutsker, J.M. Mathis, P.C. White and W.E. Rainey, 1997. Angiotensin II and potassium regulate human CYP11B2 transcription through common cis-elements. Mol. Endocrinol., 11: 638-649.
    CrossRef  |  PubMed  |  Direct Link  |  

  67. Kutteh, W.H., D.S. Miller and J.M. Mathis, 1996. Immunologic characterization of tumor markers in human ovarian cancer cell lines. J. Soc. Gynecol. Investigation, 3: 216-222.
    PubMed  |  Direct Link  |  

  68. Denner, K., W.E. Rainey, V. Pezzi, I.M. Bird, R. Bernhardt and J.M. Mathis, 1996. Differential regulation of 11β-hydroxylase and aldosterone synthase in human adrenocortical H295R cells. Mol. Cell. Endocrinol., 121: 87-91.
    CrossRef  |  Direct Link  |  

  69. Santoso, J.T., D.C. Tang, S.B. Lane, J. Hung and D.J. Reed et al., 1995. Adenovirus-based p53 gene therapy in ovarian cancer. Gynecol. Oncol., 59: 171-178.
    CrossRef  |  PubMed  |  Direct Link  |  

  70. Myeroff, L.L., R. Parsons, S.J. Kim, L. Hedrick and K.R. Cho et al., 1995. A transforming growth factor β receptor type II gene mutation common in colon and gastric but rare in endometrial cancers with microsatellite instability. Cancer Res., 55: 5545-5547.
    PubMed  |  Direct Link  |  

  71. Bird, I.M., J.M. Mathis, J.I. Mason and W.E. Rainey, 1995. Ca(2+)-regulated expression of steroid hydroxylases in H295R human adrenocortical cells. Endocrinology, 136: 5677-5684.
    CrossRef  |  PubMed  |  Direct Link  |  

  72. Barnea, A., G. Cho, G. Lu and M. Mathis, 1995. Brain-derived neurotrophic factor induces functional expression and phenotypic differentiation of cultured fetal neuropeptide Y-producing neurons. J. Neurosci. Res., 42: 638-647.
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  73. Rainey, W.H., C. Sawetawan, J.W. Shay, M.D. Michael and J.M. Mathis et al., 1994. Transformation of human granulosa cells with the E6 and E7 regions of human papillomavirus. J. Clin. Endocrinol. Metab., 78: 705-710.
    CrossRef  |  PubMed  |  Direct Link  |  

  74. Orth, K., J. Hung, A. Gazdar, M. Mathis, A. Bowcock and J. Sambrook, 1994. Ovarian tumors display persistent microsatellite instability caused by mutation in the mismatch repair gene hMSH-2. Cold Spring Harbor Symp Quantitative Boil., 59: 349-356.
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  75. Orth, K., J. Hung, A. Gazdar, A. Bowcock, J.M. Mathis and J. Sambrook, 1994. Genetic instability in human ovarian cancer cell lines. Proc. Nat. Acad. Sci., 91: 9495-9499.
    PubMed  |  Direct Link  |  

  76. Holland, O.B., J.M. Mathis, I.M. Bird and W.E. Rainey, 1993. Angiotensin increases aldosterone synthase mRNA levels in human NCI-H295 cells. Mol. Cell. Endocrinol., 94: R9-R13.
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  77. Bird, I.M., N.A. Hanley, R.A. Word, J.M. Mathis, J.L. McCarthy, J.I. Mason and W.E. Rainey, 1993. Human NCI-H295 adrenocortical carcinoma cells: A model for angiotensin-II-responsive aldosterone secretion. Endocrinology, 133: 1555-1561.
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  78. Mathis, J.M., D.M. Simmons, X. He, L.W. Swanson and M.G. Rosenfeld, 1992. Brain 4: A novel mammalian POU domain transcription factor exhibiting restricted brain-specific expression. EMBO J., 11: 2551-2561.
    PubMed  |  

  79. Kapiloff, M.S., J.M. Mathis, C.A. Nelson, C.R. Lin and M.G. Rosenfeld, 1991. Calcium/calmodulin-dependent protein kinase mediates a pathway for transcriptional regulation. Proc. Nat. Acad. Sci., 88: 3710-3714.
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  80. Prough, R.A., A.J. Sherratt, D.E. Banet, M.W. Linder, J.M. Mathis and E.R. Simpson, 1989. Modulation of the polycycuc aromatic hydrocarbon-dependent induction of cytochrome P450ia1 by glucocorticoids. Drug Metab. Rev., 20: 585-599.
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  81. Means, G.D., M.S. Mahendroo, C.J. Corbin, J.M. Mathis, F.E. Powell, C. Mendelson and E. Simpson, 1989. Structural analysis of the gene encoding human aromatase cytochrome P-450, the enzyme responsible for estrogen biosynthesis. J. Biol. Chem., 264: 19385-19391.
    Direct Link  |  

  82. Mathis, J.M., W.H. Houser, E. Bresnick, J.A. Cidlowski, R.N. Hines, R.A. Prough and E.R. Simpson, 1989. Glucocorticoid regulation of the rat cytochrome P450c (P450IA1) gene: Receptor binding within intron I. Arch. Biochem. Biophys., 269: 93-105.
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  83. Hines, R.N., J.M. Mathis and C.S. Jacob, 1988. Identification of multiple regulatory elements on the human cytochrome P450IA1 gene. Carcinogenesis, 9: 1599-1605.
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  84. Mathis, J.M., Prough, R.A., R.N. Hines, E. Bresnick and E.R. Simpson, 1986. Regulation of cytochrome P-450c by glucocorticoids and polycyclic aromatic hydrocarbons in cultured fetal rat hepatocytes. Arch. Biochem. Biophys., 246: 439-448.
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  85. Wiebkin, P., J.H. Dees, J.M. Mathis and R.A. Prough, 1985. Drug metabolism by isolated fetal human hepatocytes in suspension and primary culture. Drug Metab. Disposition, 13: 163-168.
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  86. Mathis, J.M., J.D. Johnston, P.C. Macdonald and M. Linette Casey, 1983. Steroid 21-sulfatase activity in human placenta. J. Steroid Biochem., 18: 575-579.
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  87. Garrard, L.J., J.M. Mathis and F.M. Raushel, 1983. Substrate-induced inactivation of argininosuccinate lyase by monofluorofumarate and difluorofumarate. Biochemistry, 22: 3729-3735.
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