Hi, I am H. P. Vasantha Rupasinghe, My LiveDNA is 1.6375
 
   
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Dr. H. P. Vasantha Rupasinghe
 
Highest Degree: Ph.D. in Biotechnology from University of Guelph, Canada
 
Institute: Dalhousie University, Canada
 
Area of Interest: Plant and Soil Sciences
  •   Postharvest Biochemistry
  •   Physiology
  •   Molecular Biology
  •   Horticultural Sciences
 
URL: http://livedna.org/1.6375
 
My SELECTED Publications
1:   Abachi, S., S. Lee and H.P.V. Rupasinghe, 2016. Molecular mechanisms of inhibition of Streptococcus species by phytochemicals. Molecules, 21: 215-246.
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2:   Amararathna, M., M.R. Johnston and H.P. Rupasinghe, 2016. Plant polyphenols as chemopreventive agents for lung cancer. Int. J. Molecular Sci., 17: 1352-1366.
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3:   Arumuggam, N., N.A. Bhowmick and H.P. Rupasinghe, 2015. A review: Phytochemicals targeting JAK/STAT signaling and IDO expression in cancer. Phytother. Res., 29: 805-817.
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4:   Balasuriya, B.W.N. and H.P.V. Rupasinghe, 2011. Plant flavonoids as angiotensin converting enzyme inhibitors in regulation of hypertension. Funct. Foods Health Dis., 5: 172-188.
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5:   Balasuriya, N. and H.P.V. Rupasinghe, 2012. Antihypertensive properties of flavonoid-rich apple peel extract. Food Chem., 135: 2320-2325.
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6:   Bhullar, K.B. and H.P.V. Rupasinghe, 2014. In vitro regulation of enzymes of the renin-angiotensin-aldosterone system by isoquercitrin, phloridzin and their long chain fatty acid derivatives. Functional Foods Health Dis., 4: 208-221.
7:   Bhullar, K.B. and H.P.V. Rupasinghe, 2015. Antioxidant and cytoprotective properties of partridgeberry polyphenols. Food Chem., 168: 595-605.
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8:   Bhullar, K.B., G. Lassalle-Claux, M. Touaibia and H.P.V. Rupasinghe, 2014. Antihypertensive effect of caffeic acid and its analogs through dual renin-angiotensin-aldosterone system inhibition. Eur. J. Pharmacol., 730: 125-132.
9:   Bhullar, K.S. and H.P.V. Rupasinghe, 2015. Partridgeberry polyphenols protect primary cortical and hippocampal neurons against β-amyloid toxicity. Food Res. Int., 74: 237-249.
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10:   Bhullar, K.S. and H.P.V. Rupasinghe, 2016. Partridgeberry polyphenols protect primary cortical from oxygen-glucose deprivation-reperfusion induced injury via suppression of inflammatory adipokines and regulation of HIF-1α and PPARγ. Nutr. Neurosci., 19: 260-268.
11:   Bhullar, K.S., A. Jha and H.V. Rupasinghe, 2015. Novel carbocyclic curcumin analog CUR3d modulates genes involved in multiple apoptosis pathways in human hepatocellular carcinoma cells. Chemico-Biol. Interact., 242: 107-122.
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12:   Bhullar, K.S., A. Jha, D. Youssef and H.P.V. Rupasinghe, 2013. Curcumin and its carbocyclic analogs: Structure-activity in relation to antioxidant and selected biological properties. Molecules, 18: 5389-5404.
13:   Block, K.I., C. Gyllenhaal, L. Lowe, A. Amedei and A.R. Amin et al., 2015. Designing a broad-spectrum integrative approach for cancer prevention and treatment. Seminars Cancer Biol., 35: S276-S304.
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14:   Campeau, C., J.T. Proctor, C.J.C. Jackson and H.P.V. Rupasinghe, 2003. Rust-spotted North American ginseng roots: Phenolic, antioxidant, ginsenoside and mineral nutrient content. HortScience, 38: 179-182.
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15:   Casey, S.C., A. Amedei, K. Aquilano, A.S. Azmi and F. Benencia et al., 2015. Cancer prevention and therapy through the modulation of the tumor microenvironment. Seminars Cancer Biol., 35: S199-S223.
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16:   Chen, Y., L.J. Yu and H.P.V. Rupasinghe, 2013. Effect of thermal and non‐thermal pasteurisation on the microbial inactivation and phenolic degradation in fruit juice: A mini‐review. J. Sci. Food Agric., 93: 981-986.
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17:   DeEll, J.R., D.P. Murr, M.D. Porteous and H.P.V. Rupasinghe, 2002. Influence of temperature and duration of 1-methylcyclopropene (1-MCP) treatment on apple quality. Postharvest Biol. Technol., 24: 349-353.
18:   Erkan, N., Z. Tao, H.P.V. Rupasinghe, B. Uysal and B.S. Oksal, 2012. Antibacterial activities of essential oils extracted from leaves of Murraya koenigii by solvent-free microwave extraction and hydro-distillation. Nat. Prod. Commun., 7: 121-124.
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19:   Fernando, W., H.P.V. Rupasinghe and D.W. Hoskin, 2015. Regulation of hypoxia-inducible factor-1α and vascular endothelial growth factor signaling by plant flavonoids. Mini Rev. Med. Chem., 15: 479-489.
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20:   Fernando, W., M.R.P. Coombs, D.W. Hoskin and H.P.V. Rupasinghe, 2016. Docosahexaenoic acid-acylated phloridzin, a novel polyphenol fatty acid ester derivative, is cytotoxic to breast cancer cells. Carcinogenesis, 37: 1004-1013.
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21:   Forsido, S.F., H.P.V. Rupasinghe and T. Astatkie, 2013. Antioxidant capacity, total phenolics and nutritional content in selected ethiopian staple food ingredients. Int. J. Food Sci. Nutr., 64: 915-920.
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22:   Gao, G. and H.P.V. Rupasinghe, 2012. Nutritional, physicochemical and microbial quality of ultrasound-treated apple-carrot juice blends. Food Nutr. Sci., 3: 212-218.
23:   Gao, J. and H.P.V. Rupasinghe, 2012. Characterization of 'Honeycrisp' and 'mcintosh' apple juice quality in relation to delayed cooling treatments. Open Food Sci. J., 6: 12-15.
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24:   Gao, J., H.P.V. Vasantha and N.L. Pitts, 2013. Characterisation of malolactic conversion by Oenococcus oeni to reduce the acidity of apple juice. Int. J. Food Sci. Technol., 48: 1018-1027.
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25:   George, V.C. and H.P. Rupasinghe, 2017. Apple flavonoids suppress carcinogen-induced DNA damage in normal human bronchial epithelial cells. Oxidative Med. Cell. Longevity. 10.1155/2017/1767198.
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26:   George, V.C., G. Dellaire and H.V. Rupasinghe, 2017. Plant flavonoids in cancer chemoprevention: Role in genome stability. J. Nutr. Biochem., 45: 1-14.
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27:   George, V.C., V.V. Vijesh, D.I.M. Amarararathna and H.P.V. Rupasinghe, 2016. Mechanism of action of flavonoids in prevention of inflammation-associated skin cancer. Curr. Med. Chem., 23: 1-20.
28:   Gibson, L., H.P.V. Rupasinghe, C.F. Forney and L. Eaton, 2013. Characterization of changes in polyphenols, antioxidant capacity and physico-chemical parameters during lowbush blueberry fruit ripening. Antioxidants, 2: 216-229.
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29:   Glover, K.E., S. Budge, M. Rose, H.P.V. Rupasinghe, L. MacLaren, J. Green-Johnson and A.H. Fredeen, 2012. Effect of feeding fresh forage and marine algae on the fatty acid composition and oxidation of milk and butter. J. Dairy Sci., 95: 2797-2809.
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30:   Gunathilake, K.D.P.P. and H.P.V. Rupasinghe, 2015. Recent perspectives on the medicinal potential and chemistry of ginger. Botanics: Targets Ther., 5: 55-63.
31:   Gunathilake, K.D.P.P., H.P.V. Rupasinghe and N.L. Pitts, 2013. Formulation and characterization of a bioactives-enriched fruit beverage designed for cardio-protection. Food Res. Int., 52: 535-541.
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32:   Gunathilake, K.D.P.P., L.J. Yu and H.P. Rupasinghe, 2014. Reverse osmosis as a potential technique to improve antioxidant properties of fruit juices used for functional beverages. Food Chem., 148: 335-341.
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33:   Gunathilake, K.D.P.P., Y. Wang and H.P.V. Rupasinghe, 2013. Hypocholesterolemic and hypotensive effects of a fruit-based functional beverage in spontaneously hypertensive rats fed with cholesterol-rich diet. J. Funct. Foods, 5: 1392-1401.
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34:   Hargreaves, J., M.S. Adl, P.R. Warman and H.P.V. Rupasinghe, 2008. The effects of organic amendments on mineral element uptake and fruit quality of raspberries. Plant Soil, 308: 213-226.
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35:   Hargreaves, J.C., M. Adl, P.R. Warman and H.P. Rupasinghe, 2008. The effects of organic and conventional nutrient amendments on strawberry cultivation: Fruit yield and quality. J. Sci. Food Agric., 88: 2669-2675.
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36:   Hossain, M.A., S.M. Salehuddin, M.J. Kabir, S.M.M. Rahman and H.P.V. Rupasinghe, 2009. Sinensetin, rutin, 3'-hydroxy-5, 6, 7, 4'-tetramethoxyflavone and rosmarinic acid contents and antioxidative effect of the skin of apple fruit. Food Chem., 113: 185-190.
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37:   Huber, G.M. and H.P. Rupasinghe, 2009. Phenolic profiles and antioxidant properties of apple skin extracts. J. Food Sci., 74: C693-C700.
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38:   Huber, G.M., H.P.V. Rupasinghe and F. Shahidi, 2009. Inhibition of oxidation of omega-3 polyunsaturated fatty acids and fish oil by quercetin glycosides. Food Chem., 117: 290-295.
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39:   Jackson, C.J., J.P. Dini, C. Lavandier, H.P.V. Rupasinghe and H. Faulkner et al., 2002. Effects of processing on the content and composition of isoflavones during manufacturing of soy beverage and tofu. Process Biochem., 37: 1117-1123.
40:   Jackson, C.J.C., H.P.V. Rupasinghe, T. Ayanbadejo, P. Martos and J. Schooley, 2004. Assessment of Ontario-grown ginseng (Panax quinquefolius L.) for nutritional quality and food safety. Acta Hortic., 629: 115-121.
41:   Jackson, C.J.C., J.P. Dini, C. Lavandier, H. Faulkner, H.P.V. Rupasinghe and J.T.A. Proctor, 2003. Ginsenoside content of North American ginseng (Panax quinquefolius L. Araliaceae) in relation to plant development and growing locations. J. Ginseng Res., 27: 135-140.
42:   Jha, A., K.M. Duffield, M.R. Ness, S. Ravoori and G. Andrews et al., 2015. Curcumin-inspired cytotoxic 3, 5-bis (arylmethylene)-1-(N-(ortho-substituted aryl) maleamoyl)-4-piperidones: A novel group of topoisomerase II alpha inhibitors. Bioorg. Med. Chem., 23: 6404-6417.
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43:   Jiang, Y., L. Zhang and H.V. Rupasinghe, 2017. Antiproliferative effects of extracts from Salvia officinalis L. and Saliva miltiorrhiza Bunge on hepatocellular carcinoma cells. Biomed. Pharmacother., 85: 57-67.
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44:   Jiang, Y.Y., L. Zhang and H.P.V. Rupasinghe, 2016. The anticancer properties of phytochemical extracts from Salvia plants. Botanics: Targets Therapy, 1: 25-44.
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45:   Jones, Q.R.D., J. Warford, H.P.V. Rupasinghe and G.S. Robertson, 2012. Target-based selection of flavonoids for neurodegenerative disorders. Trends Pharmacol. Sci., 33: 602-610.
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46:   Joshi, A.P.K. and H.P.V. Rupasinghe, 2010. Optimization of bioactive fortification in apple snacks through vacuum impregnation using response surface methodology. Food Nutr. Sci., 2: 45-52.
47:   Joshi, A.P.K., H.P.V. Rupasinghe and N.L. Pitts, 2010. Sensory and nutritional quality of the apple snacks prepared by vacuum impregnation process. J. Food Qual., 33: 758-767.
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48:   Joshi, A.P.K., H.P.V. Rupasinghe and N.L. Pitts, 2011. Comparison of nonfried apple snacks with commercially available fried snacks. Food Sci. Technol. Int., 17: 249-255.
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49:   Joshi, A.P.K., H.P.V. Rupasinghe, N.L. Pitts and S. Khanizadeh, 2007. Biochemical characterization of enzymatic browning in selected apple genotypes. Can. J. Plant Sci., 87: 1067-1074.
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50:   Joshi, A.P.K., H.P.V. Rupasinghe, and S. Khanizadeh, 2011. Impact of drying processes on bioactive phenolics, vitamin C and antioxidant capacity of red-fleshed apple slices. J. Food Process. Preserv., 35: 453-457.
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51:   Keddy, P.G., K. Dunlop, J. Warford, M.L. Samson, Q.R.D. Jones, H.P.V. Rupasinghe and G.S. Robertson, 2012. Neuroprotective and anti-inflammatory effects of the flavonoid-enriched fraction AF4 in a mouse model of hypoxic-ischemic brain injury. PLoS One, Vol. 7 10.1371/journal.pone.0051324.
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52:   Khanizadeh, S., D. Li, R. Tsao, D. Rekika and R. Yang et al., 2007. Phytochemical distribution among selected advanced apple genotypes developed for fresh market and processing. J. Agric. Food Environ. Sci., Vol. 1 .
53:   Khanizadeh, S., L. Ding, R. Tsao, D. Rekika, R. Yang, M.T. Charles and H.P.V. Rupasinghe, 2009. Phytochemical profiles of selected processing apple genotypes. Acta Hortic., 814: 545-550.
54:   Khanizadeh, S., R. Tsao, D. Rekika, R. Yang, M.T. Charles and H.P.V. Rupasinghe, 2008. Polyphenol composition and total antioxidant capacity of selected apple genotypes for processing. J. Food Compos. Anal., 21: 396-401.
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55:   Khanizadeh, S., R. Tsao, D. Rekika, R. Yang, M.T. Charles and H.P.V. Rupasinghe, 2009. Advances in fruit breeding in eastern canada-Role of phytochemicals in designing specialty fruits. Acta Hortic., 814: 205-208.
56:   McKellar, R.C., H.P.V. Rupasinghe, X. Lu and K.P. Knight, 2005. Analysis and classification of fruit and grape wines from different wineries using the electronic nose. J. Sci. Food Agric., 85: 2391-2396.
57:   Muche, B.M. and H.P.V. Rupasinghe, 2011. Natural antimicrobial agents of cinnamon (Cinnamomum zeylanicum L. and C. cassia) and vanilla (Vanilla planifola, V. pompon and V. tahitensis) for extending the shelf-life of fresh-cut fruits. Ethiopian J. Applied Sci., Technol., 2: 1-13.
58:   Murch, S.J., H.P.V. Rupasinghe and P.K. Saxena, 2002. An in vitro and hydroponic growing system for hypericin, pseudohypericin and hyperforin production of St. John's wort (Hypericum perforatum L. CV new stem). Planta Med., 68: 1108-1112.
59:   Murch, S.J., H.P.V. Rupasinghe, D. Goodenowe and P.K. Saxena, 2004. A metabalomic analysis of medicinal diversity in Huang-qin (Scutellaria baicalensis Georgi) genotypes: Discovery of novel compounds. Plant Cell Rep., 23: 419-425.
60:   Murch, S.J., K. Haq, H.P.V. Rupasinghe and P.K. Saxena, 2003. Nickel contamination affects growth and secondary metabolite composition of St. John's wort ( Hypericum perforatum L.). Environ. Exp. Bot., 49: 251-257.
61:   Muthuswamy, S. and H.P.V. Rupasinghe, 2007. Fruit phenolics as natural antimicrobial agents: Selective antimicrobial activity of catechin, chlorogenic acid and phloridzin. J. Food Agric. Environ., 5: 81-85.
62:   Muthuswamy, S., H.P.V. Rupasinghe and G.W. Stratton, 2008. Antimicrobial effect of cinnamon bark extract on Escherichia coli O157: H7, Listeria innocua and fresh-cut apple slices. J. Food Safety, 28: 534-549.
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63:   Nair, S.V. and H.P.V. Rupasinghe, 2014. Fatty acid esters of phloridzin induce apoptosis of human liver cancer cells through altered gene expression. PLoS One, Vol. 9. 10.1371/journal.pone.0107149.
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64:   Nair, S.V.G., M. Hettihewa and H.P.V. Rupasinghe, 2014. Apoptotic and inhibitory effects on cell proliferation of hepatocellular carcinoma HepG2 cells by methanol leaf extract of Costus speciosus. BioMed Res. Int. 10.1155/2014/637098.
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65:   Nandasiri, R. and H.P.V. Rupasinghe, 2013. Inhibition of low density lipoprotein oxidation and angiotensin converting enzyme in vitro by functional fruit vinegar beverages. J. Food Process. Beverages, 1: 5-10.
66:   Nileeka Balasuriya, H.P. Vasantha Rupasinghe, Marva Sweeney, Shelby McCarron, Katherine Gottschall-Pass 2015. Antihypertensive Effects of Apple Peel Extract on Spontaneously Hypertensive Rats Pharmacologia, 6: 371-376.
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67:   Parmar, I. and H.P.V. Rupasinghe, 2012. Optimization of dilute acid-based pretreatment and application of laccase on apple pomace. Bioresour. Technol., 124: 433-439.
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68:   Parmar, I. and H.P.V. Rupasinghe, 2013. Bio-conversion of apple pomace into ethanol and acetic acid: Enzymatic hydrolysis and fermentation. Bioresour. Technol., 130: 613-620.
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69:   Potter, E., M. Jha, K.S. Bhullar, H.V. Rupasinghe, J. Balzarini and A. Jha, 2015. Investigation of fatty acid conjugates of 3, 5-bisarylmethylene-4-piperidone derivatives as antitumor agents and human topoisomerase-IIα inhibitors. Bioorg. Med. Chem., 23: 411-421.
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70:   Proctor, J.T.A., J. A. Sullivan, H.P.V. Rupasinghe and C.J.C. Jackson, 2011. Morphological and ginsenoside differences among North American ginseng leaves. J. Ginseng Res., 35: 155-161.
71:   Ratnasooriya, C.C. and H.P.V. Rupasinghe, 2012. Extraction of phenolic compounds from grapes and their pomace using β-cyclodextrin. Food Chem., 134: 625-631.
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72:   Ratnasooriya, C.C., H.P.V. Rupasinghe and A.R. Jamieson, 2010. Juice quality and polyphenol concentration of fresh fruits and pomace of selected Nova Scotia-grown grape cultivars. Can. J. Plant Sci., 90: 193-205.
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73:   Ratnasooriya, C.C., H.P.V. Rupasinghe and N.L. Pitts, 2012. Physicochemical and sensory evaluation of non-alcoholic wine-like beverages prepared from selected grape cultivars. J. Nutr. Food Sci., Vol. 2 .
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74:   Rupasinghe, H.P.V and A. Yasmin, 2010. Inhibition of oxidation of aqueous emulsions of omega-3 fatty acids and fish oil by phloretin and phloridzin. Molecules, 15: 251-257.
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75:   Rupasinghe, H.P.V. and C. Kean, 2008. Polyphenol concentrations in apple processing by-products determined using electrospray ionization mass spectrometry. Can. J. Plant Sci., 88: 759-762.
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76:   Rupasinghe, H.P.V. and R.J. Gladon, 2000. Glutamic acid and 5-aminolevulenic acid enhance System 2 ethylene in ripening tomato fruits. J. Plant Physiol. Mol. Biol., 6: 27-33.
77:   Rupasinghe, H.P.V. and S. Clegg, 2007. Total antioxidant capacity, total phenolic content, mineral elements and histamine concentrations in wines of different fruit sources. J. Food Compos. Anal., 20: 133-137.
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78:   Rupasinghe, H.P.V., B.C.N. Peiris and S.W. Wijerathnam, 1993. A case study on identification and assessment of postharvest losses of tomato (Lycoperisicon escuentum Mill). Trop. Agric. Res., 4: 41-47.
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79:   Rupasinghe, H.P.V., C. Kean, D. Nichols and C. Embree, 2007. Orchard waste as a valuable bio-resource: A chemical composition analysis. Acta Hortic., 737: 17-23.
80:   Rupasinghe, H.P.V., C.J.C. Jackson, V. Poysa and J. Kinjo, 2004. A rapid method to analyze saponin precursors in soybean (Glycine max (L.) Merrill). Acta Hortic., 629: 139-143.
81:   Rupasinghe, H.P.V., C.J.C. Jackson, V. Poysa, C. Di Berardo, J.D. Bewley and J. Jenkinson, 2003. Soyasapogenol A and B distribution in soybean (Glycine max L. Merr.) in relation to seed physiology, genetic variability and growing location. J. Agric. Food Chem., 51: 5888-5894.
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82:   Rupasinghe, H.P.V., C.M. Ronalds, B. Rathgeber and R.A. Robinson, 2010. Absorption and tissue distribution of dietary quercetin and quercetin glycosides of apple skin in broiler chickens. J. Sci. Food Agric., 90: 1172-1178.
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83:   Rupasinghe, H.P.V., D.P. Murr, G. Paliyath and J.R. DeEll, 2000. Suppression of a-farnesene synthesis in 'Delicious' apples by aminoethoxyvinylglycine (AVG) and 1-methylcyclopropene (1-MCP). J. Plant Phyiol. Mol. Biol., 6: 195-198.
84:   Rupasinghe, H.P.V., D.P. Murr, J.R. DeEll and J.A. Odumeru, 2005. Influence of 1-methylcyclopropene (1-MCP) and NatureSealTM on the quality of fresh-cut ''Empire'' and ''Crispin'' apples. J. Food Qual., 28: 289-307.
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85:   Rupasinghe, H.P.V., G. Paliyath and D.P. Murr, 1998. Biosynthesis of α-farnesene and its relation to superficial scald development in 'Delicious' apples. J. Am. Soc. Hort. Sci., 123: 882-886.
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86:   Rupasinghe, H.P.V., G. Paliyath and D.P. Murr, 2000. Sesquiterpene α-farnesene synthase: partial purification, characterization and activity in relation to superficial scald development in apples. J. Am. Soc. Hort. Sci., 125: 111-119.
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87:   Rupasinghe, H.P.V., G. Paliyath and D.P. Murr, 2003. A review: Biosynthesis of isoprenoids in higher plants. J. Plant Physiol. Mol. Biol., 9: 19-28.
88:   Rupasinghe, H.P.V., G.M. Huber, C. Embree and P.L. Forsline, 2010. Red-fleshed apple as a source for functional beverages. Can. J. Plant Sci., 90: 95-100.
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89:   Rupasinghe, H.P.V., I. Parmar and L. Yu, 2013. Value-added fruit processing and human health: Global perspectives. Ethiopian J. Applied Sci. Technol., 3: 27-39.
90:   Rupasinghe, H.P.V., J. Boulter-Bitzer and J.A. Odumeru, 2006. Lactic acid improves the efficacy of anti-microbial washing solutions for apples. J. Food Agric. Environ., 4: 44-48.
91:   Rupasinghe, H.P.V., J. Boulter-Bitzer, T. Ahn and J.A. Odumeru, 2006. Vanillin inhibits pathogenic and spoilage microorganisms in vitro and aerobic microbial growth in fresh-cut apples. Food Res. Int., 39: 575-580.
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92:   Rupasinghe, H.P.V., K.C. Almquist, G. Paliyath and D.P. Murr, 2001. Cloning of hmg1 and hmg2 cDNAs encoding 3-hydroxy-3-methylglutaryl coenzyme A reductase and their expression and activity in relation to α-farnesene synthesis in apple. Plant Physiol. Biochem., 39: 933-947.
93:   Rupasinghe, H.P.V., K.C. Almquist, G. Paliyath, D.P. Murr, T.E. Elthon and A.C. Purvis, 2003. Involvement of the alternative oxidase (AOX) in superficial scald: Isolation and sequence analysis of the apple AOX1 cDNA. Acta Hortic., 628: 481-486.
94:   Rupasinghe, H.P.V., L. Wang, G.M. Huber and N.L. Pitts, 2008. Effect of baking on dietary fibre and phenolics of muffins incorporated with apple skin powder. Food Chem., 107: 1217-1224.
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95:   Rupasinghe, H.P.V., L. Wang, N.L. Pitts and T. Astatkie, 2009. Baking and sensory characteristics of muffins incorporated with apple skin powder. J. Food Qual., 32: 685-694.
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96:   Rupasinghe, H.P.V., L. Yu, K. Bhullar and B. Bors, 2012. Haskap (Lonicera caerulea): A new berry crop with high antioxidant capacity. Can. J. Plant Sci., 92: 1311-1317.
97:   Rupasinghe, H.P.V., M.A. Boehm, S. Sekhon-Loodu, I. Parmar, B. Bors and A.R. Jamieson, 2015. Anti-inflammatory activity of haskap (Lonicera caerulea L.) cultivars is dependent on their polyphenol content. Biomolecules, 5: 1079-1098.
98:   Rupasinghe, H.P.V., N. Erkan and A. Yasmin, 2010. Antioxidant protection of eicosapentaenoic acid and fish oil oxidation by polyphenolic-enriched apple skin extract. J. Agric. Food Chem., 58: 1233-1239.
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99:   Rupasinghe, H.P.V., P. Kathirvel and G.M. Huber, 2011. Ultrasonication-assisted solvent extraction of quercetin glycosides from 'Idared' apple peels. Molecules, 16: 9783-9791.
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100:   Rupasinghe, H.P.V., S. Jayasankar and W. Lay, 2006. Variation in total phenolics and antioxidant capacity among European plum genotypes. Sci. Hortic., 108: 243-246.
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101:   Rupasinghe, H.V., S. Sekhon-Loodu, T. Mantso and M.I. Panayiotidis, 2016. Phytochemicals in regulating fatty acid β-oxidation: Potential underlying mechanisms and their involvement in obesity and weight loss. Pharmacol. Therapeut., 165: 153-163.
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102:   Rupersinghe, H.P.V., D.P. Murr, G. Paliyath and L. Skog, 2000. Inhibitory effect of 1-MCP on ripening and superficial scald development in 'McIntosh' and delicious apples. J. Hort. Sci. Biotechnol., 75: 271-276.
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103:   Samadi, A.K., A. Bilsland, A.G. Georgakilas, A. Amedei and A. Amin et al., 2015. A multi-targeted approach to suppress tumor-promoting inflammation. Seminars Cancer Biol., 35: S151-S184.
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104:   Sekhon-Loodu, S. and H.P.V. Rupasinghe, 2015. Docosahexaenoic acid ester of phloridzin inhibit lipopolysaccharide-induced inflammation in THP-1 differentiated macrophages. Int. Immunopharmacol., 25: 199-206.
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105:   Sekhon-Loodu, S., A. Catalli, M. Kulka, Y. Wang, F. Shahidi and H.P.V. Rupasinghe, 2014. Combination of apple flavonols and omega-3 fatty acid-rich fish oil improves the efficacy of lowering blood C-reactive protein in rats with hypercholesterolemia and acute inflammation. Nutr. Res., 34: 535-543.
106:   Sekhon-Loodu, S., S.N. Warnakulasuriya, H.P.V. Rupasinghe and F. Shahidi, 2013. Antioxidant ability of fractionated apple peel phenolics to inhibit fish oil oxidation. Food Chem., 140: 189-196.
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107:   Sekhon-Loodu, S., Z. Ziaullah, H.V. Rupasinghe, Y. Wang, M. Kulka and F. Shahidi, 2015. Novel quercetin-3-O-glucoside eicosapentaenoic acid ester ameliorates inflammation and hyperlipidemia. Inflammopharmacology, 23: 173-185.
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108:   Soundararajan, R., A.D. Wishart, H.P.V. Rupasinghe, M. Arcellana-Panlilio, C.M Nelson, M. Mayne and G.S. Robertson, 2008. Quercetin 3-glucoside protects neuroblastoma (SH-SY5Y) cells in vitro against oxidative damage by inducing sterol regulatory element-binding protein-2-mediated cholesterol biosynthesis. J. Biol. Chem., 284: 2231-2245.
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109:   Sudan, S. and H.P.V. Rupasinghe, 2014. Flavonoid-enriched apple fraction AF4 induces cell cycle arrest, DNA topoisomerase II inhibition and apoptosis in human liver cancer HepG2 cells. Nutr. Cancer, 66: 1237-1246.
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110:   Sudan, S. and H.P.V. Rupasinghe, 2014. Quercetin-3-O-glucoside induces human DNA topoisomerase II inhibition, cell cycle arrest and apoptosis in hepatocellular carcinoma cells. Anti-Cancer Res., 34: 1691-1699.
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111:   Sudan, S. and H.P.V. Rupasinghe, 2015. Antiproliferative activity of long chain acylated esters of quercetin-3-O-glucoside in hepatocellular carcinoma HepG2 cells. Exp. Biol. Med., 240: 1452-1464.
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112:   Taylor, N., A.M. Hammermeister, H.P.V. Rupasinghe and K. Pruski, 2013. Characterization of Ribes nigrum in relation to fruit maturity and genotype. Acta Hortic., 1001: 199-205.
113:   Thilakarathna, S.H. and H.P.V. Rupasinghe, 2012. Anti-atherosclerotic effects of fruit bioactive compounds: A review of current scientific evidence. Can. J. Plant Sci., 92: 407-419.
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114:   Thilakarathna, S.H. and H.P.V. Rupasinghe, 2013. Flavonoid bioavailability and attempts for bioavailability enhancement. Nutrients, 5: 3367-3387.
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115:   Thilakarathna, S.H., H.P.V. Rupasinghe and P.W. Needs, 2013. Apple peel bioactive rich extracts effectively inhibit in vitro human LDL cholesterol oxidation. Food Chem., 138: 463-470.
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116:   Thilakarathna, S.H., Y. Wang, H.P.V. Rupasinghe and K. Ghanam, 2012. Apple peel flavonoid-and triterpene-enriched extracts differentially affect cholesterol homeostasis in hamsters. J. Funct. Foods, 4: 963-971.
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117:   Warford, J., Q.R. Jones, M. Nichols, V. Sullivan, H.V. Rupasinghe and G.S. Robertson, 2014. The flavonoid-enriched fraction AF4 suppresses neuroinflammation and promotes restorative gene expression in a mouse model of experimental autoimmune encephalomyelitis. J. Neuroimmunol., 268: 71-83.
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118:   Warnakulasuriya, S.N., Ziaullah and H.P.V. Rupasinghe, 2016. Long chain fatty acid esters of quercetin-3-O-glucoside attenuate H2O2-induced acute cytotoxicity in human lung fibroblasts and primary hepatocytes. Molecules, 21: 452-471.
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119:   Warnakulasuriya, S.N., Ziaullah and H.P.V. Rupasinghe, 2016. Novel long chain fatty acid derivatives of quercetin-3-O-glucoside reduce cytotoxicity induced by cigarette smoke toxicants in human fetal lung fibroblasts. Eur. J. Pharmacol., 781: 128-138.
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120:   Whiting, M.D., H.P.V. Rupasinghe, D.P. Murr, G. Paliyath and D.D. Rowan, 2003. Effect of alpha-farnesene and its metabolites on membrane properties of 'Delicious' apples. Acta Hortic., 628: 627-633.
121:   Yu, L. and H.P.V. Rupasinghe, 2013. Improvement of cloud stability, yield and β-carotene content of carrot juice by process modification. Food Sci. Technol. Int., 19: 399-406.
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122:   Yu, L.J. and H.V.P. Rupasinghe, 2012. Effect of acidification on quality and shelf-life of carrot juice. Can. J. Plant Sci., 92: 1113-1120.
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123:   Ziaullah and H.P.V. Rupasinghe, 2013. An efficient microwave-assisted enzyme-catalyzed regioselective synthesis of long chain acylated derivatives of flavonoid glycosides. Tetrahedron Lett., 54: 1933-1937.
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124:   Ziaullah and H.P.V. Rupasinghe, 2016. Sonochemical enzyme-catalyzed regioselective acylation of flavonoid glycosides. Bioorg. Chem., 65: 17-25.
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125:   Ziaullah, K.S. Bhullar, S.N. Warnakulasuriya and H.P.V. Rupasinghe, 2013. Biocatalytic synthesis, structural elucidation, antioxidant capacity and tyrosinase inhibition activity of long chain fatty acid acylated derivatives of phloridzin and isoquercitrin. Bioorg. Med. Chem., 21: 684-692.
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126:   Zobayed, S.M.A., S.J. Murch, H.P.V. Rupasinghe and P.K. Saxena, 2003. Elevated carbon supply altered hypericin and hyperforin contents of St. John's wort (Hypericum perforatum L. cvNew Stem) grown in bioreactors. Plant Cell Tissue Organ Cult., 75: 143-149.
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127:   Zobayed, S.M.A., S.J. Murch, H.P.V. Rupasinghe and P.K. Saxena, 2004. In vitro production and chemical characterization of St. Johns wort (Hypericum perforatum L. cv. New Stem). Plant Sci., 166: 333-340.
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128:   Zobayed, S.M.A., S.J. Murch, H.P.V. Rupasinghe, J.G. De Boer, B.W. Glickman and P.K. Saxena, 2004. Optimized system for biomass production, chemical characterization and evaluation of chemo-preventive properties of Scutellaria baicalensis Georgi. Plant Sci., 167: 439-446.
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