Dr. Tarek Hassan El-Metwally
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Dr. Tarek Hassan El-Metwally

Professor
Assiut University, Egypt


Highest Degree
Ph.D. in Medical Biochemistry from Creighton University Medical Center, NE, USA

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Biography

Dr. Tarek H. El-Metwally is currently working as Professor at Department of Medical Biochemistry, Faculty of Medicine, Assiut University, Assiut, Egypt. He obtained his Ph.D. in Medical Biochemistry from Creighton University Medical Center, NE, USA. Dr. Tarek H. El-Metwally received honors includes Fourth position Award (Midwest Student Research Forum, MSRF), Omaha, NE, USA, Travel Award (American Pancreatic Association, APA, Annual Meeting), Chicago, USA, Travel Award (The Joint conference of the International Association of Pancreatology and the Japan Pancreas Society), Sendai, Japan, and The Best Department Staff - teaching and cooperating with the students, Students Nomination, 2003/2004 and 2004/2005, Faculty of Medicine, Assiut University, Assiut, Egypt. He is also editor/author of 11 international books and review articles. He is also serving as reviewer and editor board member in number of journals. He is also working as CME Coordinator Aljouf College of Medicine, Aljouf University, Sakaka, Saudi Arabia, and Associate Editor-In-Chief: Aljouf Medical Journal is an online Open-Access and printed Multidisciplinary Peer-Reviewed International Journal that is published bimonthly by the Deanship for Graduate Studies and Scientific Research, University of Aljouf, Sakaka, Saudi Arabia. He has examined at least 10 research projects for local and international funding. He is member of following scientific societies, Egyptian Society for Biochemistry & Molecular Biology, American Pancreatic Association, Society of Inimitability of Quran and Sunnah, Whos Who in the World, NJ, USA, Egyptian Society of Clinical Chemistry, and Arabic Translation & Intercultural Dialogue Association. His current area of interest related to Retinoids Clinical Application in Medicine, Cancer Redifferentiation Therapy, in Vitro and in Vivo Stem Cell Biology in Diabetes, Thalassemia, Azoospermia, Autoimmune Diseases and Obesity, Characterization of Tissue Hypoxia Biomarkers as Alternative early Organ Function Tests. He is also working on 11 projects and received grants for his research work. He supervised more than 27 PhD, Msc, and Medical Doctorate. He has published 22 articles in international journals, and 11 articles in national journals, 26 presentations in conferences contributed as author/co-author.

Area of Interest:

Molecular Sciences
100%
Clinical Biochemistry
62%
Molecular Biology
90%
Cancer Biology
75%
Microbiology
55%

Research Publications in Numbers

Books
3
Chapters
0
Articles
38
Abstracts
0

Selected Publications

  1. Yones, D.A., E.A. Mahmoud, R.A. Othman, M. Korany and T.H. El-Metwally, 2014. Viability loss and ultrastructural changes on protoscolices of human hydatid cysts induced by retinoic acid. J. Parasitol. Vector Biol., 6: 189-197.
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  2. Tadesse, F.G., Y. Worku, Y. Feleke and T.H. El-Metwally, 2014. Metabolic syndrome biomarkers in Type II diabetic Ethiopian patients. J. Metab. Synd, 3: 1-5.
  3. Ragab, S.M.M., H.M. Omar, S.K. Abd Elghaffar and T.H. El-Metwally, 2014. Hypolipidemic and antioxidant effects of phytochemical compounds against hepatic steatosis induced by high fat high sucrose diet in rats. Arch. Biomed. Sci., 2: 1-10.
  4. Elsayh, K.I., A.M. Zahran, T.B. El-Abaseri, A.O. Mohamed and T.H. El-Metwally, 2014. Hypoxia biomarkers, oxidative stress and circulating microparticles in pediatric patients with thalassemia in upper Egypt. Clin. Applied Thromb./Hemostasis, 20: 536-545.
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  5. Wahba, O.M., S.K. Abd-Elshafy, G.A. Makhlouf, T.H. ElMetwly and N.F. Abd El-Hafez, 2013. Is obesity a possible risk factor for oxidative stress in female patient during general anesthesia? Al-Azhar Assiut Med. J., 11: 186-212.
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  6. Hamed, E.A., T.B. El-Abaseri, A.O. Mohamed, A.R. Ahmed and T.H. El-Metwally, 2012. Hypoxia and oxidative stress markers in pediatric patients undergoing hemodialysis: Cross section study. BMC Nephrol., Vol. 13. 10.1186/1471-2369-13-136.
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  7. Omar, O.S., T.H. El-Metwally, A.M. Meki and M.M. Anwar, 2011. Impact of oxidative stress and smoking on muscle fatigue markers during a single bout of exercise. Assiut Med. J., 25: 39-52.
  8. Zahran, M.S., M.N. Abdel-Hafez, M.G. Rabei, T.H. El-Metwally and K.K. Abdul-Aziz, 2010. Oxidant-antioxidant balance and iron overload: Impact on pulmonary function in thalassemic children. Adv. Med. Biol., 10: 52-95.
  9. Hamed, E.A., N.A. Mohamed, T.H. El-Metwally and M.M. Kamal, 2010. Iron chelation therapy in upper Egyptian transfusion-dependent pediatric homozygous β-thalassemia major: Impact on serum L-carnitine/free fatty acids, osteoprotegerin/the soluble receptor activator of nuclear factor κ β ligand systems and bone mineral density. J. Pediatr. Hematol. Oncol., 32: 267-273.
    CrossRef  |  
  10. Addisu, S., T.H. El-Metwally, G. Davey, Y. Worku and M.A. Titheradge, 2010. The role of transforming growth factor-β1 and oxidative stress in podoconiosis pathogenesis. Br. J. Dermatol., 16: 998-1003.
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  11. El-Metwally, T.H., M.B. El-Salahy, M.J. Tourkey, H.A.K. Ali, A.H.A. Abdul Haleem and K.A. Hassan, 2009. Apoptotic markers, VEGF and TGF-α levels in the gastric ulceration Shay Rat model: Towards a commonplace mechanism of action for copper-glycinate and -nicotinate complexes. Arab J. Lab. Med., 35: 269-284.
  12. Othmana, E.E.D.R., D. Hornung, H.T. Salem, E.A. Khalifa, T.H. El-Metwally and A. Al-Hendy, 2008. Serum cytokines as biomarkers for nonsurgical prediction of endometriosis. Eur. J. Obstet. Gynecol. Reprod. Biol., 137: 240-246.
    CrossRef  |  
  13. Hameed, D.A. and T.H. El-Metwally, 2008. The effectiveness of retinoic acid treatment in bladder cancer: Impact on recurrence, survival and TGFα and VEGF as end-point biomarkers. Cancer Biol. Ther., 7: 92-100.
    CrossRef  |  
  14. El-Metwally, T.H., P.M. Pour, 2007. The retinoid induced pancreatic cancer redifferentiation-apoptosis sequence and the mitochondria: A suggested obligatory sequence of events. J. Pancreas, 8: 268-278.
    PubMed  |  Direct Link  |  
  15. Abdel-Hafez, N.M., Y.S. Hassan and T.H. El-Metwally, 2007. A study on biomarkers, cytokines and growth factors in children with burn injuries. Ann. Burns Fire Disasters, 20: 89-100.
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  16. El-Metwally, T.H., M.R. Hussein, S.K. Abd-El-Ghaffar, M.M. Abo-El-Naga, A.B. Ulrich and P.M. Pour, 2006. Retinoic acid can induce markers of endocrine transdifferentiation in pancreatic ductal adenocarcinoma: Preliminary observations from an in vitro cell line model. J.Clin. Pathol., 59: 603-610.
    PubMed  |  Direct Link  |  
  17. Abdel-Hafez, N.M., G.M. Rabei and T.H. El-Metwally, 2006. A cardiopulmoary study on thalassemic children: Relation to oxidant-antioxidant balance and ion overload. Alexandria J. Pediatr., 20: 285-296.
  18. El-Metwally, T.H., M.R. Hussein, P.M. Pour, C.A. Kuszynski and T.E. Adrian, 2005. Natural retinoids inhibit proliferation and induce apoptosis in pancreatic cancer cells previously reported to be retinoid resistant. Cancer Biol. Ther., 4: 474-483.
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  19. El-Metwally, T.H., M.R. Hussein, P.M. Pour, C.A. Kuszynski and T.E. Adrian, 2005. High concentrations of retinoids induce differentiation and late apoptosis in pancreatic cancer cells in vitro. Cancer Biol. Ther., 4: 602-611.
    CrossRef  |  
  20. El-Deeb, S.A., S.E. Amry, T.H. El-Metwally and H.M.A. Al-Jefri, 2005. A study of some biochemical parameters of pulmonary hypertension in children with congenital and rheumatic heart disease. Alexandria J. Pediatr., 19: 121-126.
  21. El-Metwally, T.H., H.M.G. Rashed and O.A. Osman, 2003. Diagnostic value of serum procalcitonin as a marker of bacterial infection in cirrhotic patients with fever: Correlation with interleukin 6. Assiut. Med. J., 27: 89-89.
  22. El-Metwally, T.H., E.A. Hamed, A.R. Ahmad and N.A. Mohamed, 2003. Dyslipidemia, oxidative stress and cardiac dysfunction in children with chronic renal failure: Effects of L-carnitine supplementation. Ann. Saudi Med., 23: 270-277.
    PubMed  |  
  23. Adel-Raheim, M.M., T.H. El-Metwally, A.E. Abdel-El-Moneim, M.A. Ashry and T.M. Kamal, 2003. Role of leptin in diabetic and hypertensive patients: Its relationship to other cardiovascular risk factors. Egypt. J. Biochem. Mol. Biol., 21: 105-122.
  24. Abdel-Hafez, N.M., M.A.M. Abd-El Rheim, H.M. Abdel-Monem, A.R. Ahmed and T.H. El-Metwally, 2003. Angiogenesis associating liver cirrhosis in children. Alexandria J. Pediat., 17: 385-393.
  25. Abd-El Rheim, M.A.M., E.A.S. Elbeih, T.H. El-Metwally and A.M. Abdel-Ghani, 2003. Serum levels of soluble Fas ligand, TNF-α and their soluble receptors in type I and type II diabetic patients: Relationship with glycemic control and oxidative stress. Arab J. Clin. Chem., 29: 181-198.
  26. Ulrich, A.B., B.M. Schmied, H. Matsuzaki, T.H. El-Metwally and M.P. Moyer et al., 2000. Establishment of human pancreatic ductal cells in a long-term culture. Pancreas, 21: 358-368.
    PubMed  |  Direct Link  |  
  27. Schmied, B.M., A.B. Ulrich, H. Matsuzaki, T.H. El-Metwally and X. Ding et al., 2000. Biologic instability of pancreatic cancer xenografts in the nude mouse. Carcinogenesis, 21: 1121-1127.
    PubMed  |  Direct Link  |  
  28. Choudhury, A., R.K. Singh, N. Moniaux, T.H. El-Metwally, J.P. Aubert and S.K. Batra, 2000. Retinoic acid-dependent transforming growth factor-β2-mediated induction of MUC4 mucin expression in human pancreatic tumor cells follows retinoic acid receptor-α signaling pathway. J. Biol. Chem., 275: 33929-33936.
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  29. El-Metwally, T.H. and T.E. Adrian, 1999. Optimization of treatment conditions for studying the anticancer effects of retinoids using pancreatic adenocarcinoma as a model. Biochem. Biophys. Res. Commun., 257: 596-603.
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  30. Ding, X.Z., C.A. Kuszynski, T.H. El-Metwally and T.E. Adrian, 1999. Lipoxygenase inhibition induced apoptosis, morphological changes and carbonic anhydrase expression in human pancreatic cancer cells. Biochem. Biophys. Res. Commun., 266: 392-399.
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  31. El-Saadani, M.A., A.Y. Nassar, S.H. Abou El-Ela, T.H. El-Metwally and A.M. Nafady, 1993. The protective effect of copper complexes against gastric mucosal ulcer in rats. Biochem. Pharmacol., 46: 1011-1018.
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