Dr. Karima  Fathy Mahrous
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Dr. Karima Fathy Mahrous

Professor
National Research Center, Egypt


Highest Degree
Ph.D. in Genetics from Cairo University, Egypt

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Area of Interest:

Biomedical Sciences
100%
Gene Cloning
62%
Genetic Variations
90%
Screening
75%
Recombinant Proteins
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Shafey, H.I., M.D. Aboelhassan, E.M. El-Komy, R.E. Abd El-Karim and K.F. Mahrous, 2017. SNP of cGH gene in Egyptian chicken breeds at MspI site. Biosci. Biotechnol. Res. Asia, 14: 33-41.
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  2. Mahrous, K.F., H.I. Shafey, E.A. Balabel and O.E. Othman, 2017. Genetic biodiversity analysis of two mitochondrial genes in Arabian and thoroughbred horses. Biosci. Biotechnol. Res. Asia, 14: 25-32.
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  3. Barakat, I.A.H., L.M. Salem, N.M. Daoud, W.K.B. Khalil and K.F. Mahrous, 2017. Genetic polymorphism of candidate genes for fecundity traits in Egyptian sheep breeds. Biomed. Res., 28: 851-857.
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  4. Aboelenin, M.M., K.F. Mahrous, A. Elkerady and M.A. Rashed, 2017. Molecular characterization of cytochrome P450 aromatase (CYP19) gene in Egyptian river buffaloes. Egypt. J. Genet. Cytol., 46: 305-311.
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  5. Abdel Hafez, M., K. Mahrous, S.H. Abdel-Aziem and M. Abdel Mordy, 2017. Screening of IGF-I and IGFBP-3 genes polymorphism in popular Goat breeds in Egypt. J. Pharmaceut. Biol. Sci., 5: 8-14.
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  6. Mahrous, K.F., M.S. Hassanane, H.I. Shafey, M.A. Mordy and H.E. Rushdi, 2016. Association between single nucleotide polymorphism in ovine Calpain gene and growth performance in three Egyptian sheep breeds. J. Genet. Eng. Biotechnol., 14: 233-240.
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  7. Hanafy, Z.E.M., H.A.E.S. Eldawy, K.F. Mahrous and A.K. Mohamed, 2016. Role of quercetin against 2-butoxyethanol induced micronucleus and chromosome aberrations in mice. Egypt. J. Hospital Med., 64: 311-318.
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  8. Bakr, M.N., M.D. Aboelhassan, A. Elgindy, N.S. Gad and K.F. Mahrous, 2016. Genotoxic and histopathological effects of water pollutants in three population fish (Oreochromis niloticus) in Egypt. Int. J. Pharmaceut. Sci. Rev. Res., 38: 206-215.
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  9. Baawad, F.A.M., S.Y.M. Alakilli and K.F. Mahrous, 2016. Selenium increases the efficiency of bone marrow stem cells in repairing the liver damage induced by CCl4 in male rats. Int. J. Pharmaceut. Sci. Rev. Res., 38: 135-143.
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  10. Mahrous, K.F., A.M. Hassan, H.A. Radwan and M.A. Mahmoud, 2015. Inhibition of cadmium-induced genotoxicity and histopathological changes in Nile tilapia fish by Egyptian and Tunisian montmorillonite clay. Ecotoxicol. Environ. Saf., 119: 140-147.
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  11. Mahmoud, K., W.K.B. Khalil, O.A. Elmoniem and K.F. Mahrous, 2015. Evaluation of Ficus glomerata extract as potential anticancer agents and prevents the genetic toxicity induced by benzo(a)pyrene in male mice. Int. J. PharmTech Res., 8: 678-690.
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  12. Alam, S.S., H.A.M. Abd El-Kader, S.I. Abd El-Moez, N.M. Sabry, A.M. Kenawy and K.F. Mahrous, 2015. Using expression of immune response genes and histopathological changes in Tilapia zilli as a biomarker to bacterial infection in lake Qarun. Asian J. Microbiol. Biotechnol. Environ. Sci., 17: 819-830.
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  13. Alakilli, S.Y.M., W.K.B. Khalil and K.F. Mahrous, 2015. The protective effect of thymoquinone against lead acetate induced DNA damage and alterations in tumor initiation genes. Asian J. Pharmaceut. Clin. Res., 8: 302-308.
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  14. Alakilli, S.Y.M. and K.F. Mahrous, 2015. Evaluation the chemopreventive impacts of lactoferrin on the initiation of liver cancer induced by diethylnitrosamine in male mice. Int. J. Pharmaceut. Sci. Rev. Res., 32: 59-66.
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  15. Shafey, H.I., K.F. Mahrous, M.S. Hassanane, M. Abdel Mordy and H.E. Rushdi, 2014. Genetic polymorphism of myostatin and insulin-like growth factor binding protein-3 genes in Egyptian sheep breeds. Global Vet., 13: 419-424.
  16. Salman, A.S., L.M. Salem, A.A. Farghaly and K.F. Mahrous, 2014. Protective effect of vitamin D3 against flutamide induced genotoxicity. Int. J. Pharmaceut. Sci. Rev. Res., 29: 122-130.
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  17. Mahrous, K.F., N.M. Sabry, N.H. Altwaty and L.M. Salem, 2014. Molecular comparative study of Growth Hormone Receptor (GHR) gene in Egyptian and Saudi breeds of sheep (Ovis aries). Int. J. Adv. Res., 2: 1102-1111.
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  18. Abdel-Hamid, Z.G., A.M. Heba, A. El-Kader, D.M. Aboelhassan and K.F. Mahrous, 2014. Genetic diversity in egyptian tilapia species using pcr-rflp of d-loop mitochondrial DNA gene. Res. J. Pharm. Biol. Chem. Sci., 5: 469-475.
  19. Abd El-Kader, H.A.M., S.S. Alama, A.A. Nafeaa and K.F. Mahrous, 2014. Influence of dietary supplementation of mannanoligosaccharide (Bio-Mos®) prebiotic on the genotoxic and antioxidant status in Japanese quail. Int. J. Pharmaceut. Sci. Rev. Res., 27: 289-295.
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  20. Abd El-Kader, H.A.M., Z.G. Abd El-Hamid and K.F. Mahrous, 2013. Genetic diversity among three species of Tilapia in Egypt detected by random amplified polymorphic DNA marker. J. Applied Biol. Sci., 7: 57-64.
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  21. Soror, E., K.F. Mahrous, I.A. Eissa and A.A. Abbass, 2012. Incidence of Proliferative Kidney Disease (PKD) in tilapia (Oreachromus niloticus) and catfish (Clarius gariepinus). Benha Vet. Med. J., 23: 159-170.
  22. Soror, E., K.F. Mahrous, I.A. Eissa and A.A. Abbass, 2012. Epizotiological studies on proliferative kidney disease in tilapia (Oreochromis niloticus) and African catfish (Clarias gariepinus). Benha Vet. Med. J., 23: 150-158.
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  23. Hussein, E.H.A., K.F. Mahrous, A. Gaber, N. El-Halawany and M. Maghawry, 2012. Identification of genes preferentially expressed during in-vitro buffalo oocyte maturation using the differential display technique. a. Genes involved in DNA replication, repair and cell cycle, signal transduction and cell-to-cell communication and anti-apoptosis. Arab J. Biotechnol., 15: 1-16.
  24. Daoud, N.M., K.F. Mahrous and O.H. Ezzo, 2012. Feed restriction as a biostimulant of the production of oocyte, their quality and GDF-9 gene expression in rabbit oocytes. Anim. Reprod. Sci., 136: 121-127.
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  25. Daoud, N.M., A.H. Abd-El-Rahman, K.F. Mahrous, W.B. Khalil and O.H. Ezzo, 2012. GDF-9 GDF-9 gene expression, oocyte qulaity, hematological and biochemical profiles affected by feed restriction as a biostimulant method on rabbits' fertility. Glob Vet., 8: 532-540.
  26. Alakilli, S.Y., K.F. Mahrous, L.M. Salem and E.S. Ahmed, 2012. Genetic polymorphism of five genes associated with growth traits in goat. Afr. J. Biotechnol., 11: 14738-14748.
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  27. Mahrous, K.F., R. Hassan, S.H. Abdel-Aziem, M. Abd-El Mordy, and D.M. Hemdan, 2011. Genetic variation between camels breeds using microsatellite markers and RAPD techniques. J. Applied Biosci., 39: 2626-2634.
  28. Mahrous, K.F., M. Hassanane, M.A. Mordy, H.I. Shafey and N. Hassan, 2011. Genetic variations in horse using microsatellite markers. J. Genet. Eng. Biotechnol., 9: 103-109.
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  29. Abdelatey, L.M., W.K.B. Khalil, T.H. Ali and K.F. Mahrous, 2011. Heavy metal resistance and gene expression analysis of metal resistance genes in gram-positive and gram-negative bacteria present in egyptian soils. J. Appl. Sci. Environ. Sanit. Sby., 6: 201-211.
  30. Mahrous, K.F., S.S. Alam and A.M. Hassan, 2010. Genetic variations between horse breeds using RAPD markers. Nat. Sci., 8: 90-99.
  31. Khalil, W.K.B., S.S. Alam, I.A.H. Barakat, A.M. Hassan and K.F. Mahrous, 2010. Effect of in vitro culture on the expression of genes enhanced meiotic progression in Egyptian buffalo oocytes. J. Appl. Biosci., 32: 1977-1988.
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  32. Abdel-Aziem, S.H., L.M. Salem, M.S. Hassanane and K.F. Mahrous, 2010. Genetic analysis between and within three egyptian water buffalo populations using RAPD-PCR. J. Am. Sci., 6: 217-226.
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  33. Riffat, H.M., K.F. Mahrous and W.K.B. Khalil, 2009. Effect of the heavy metals upon metallothioneins in some streptomyces species isolated from egyptian soil. J. Applied eEviron. Valid., 4: 197-206.
  34. El-makawy, A.I. and K.F. Mahrous, 2008. Antimutagenic activity of some natural supplements on ivermectin genotoxicity in lymphocytes of buffalo. Egypt. J. Hospital Med., 30: 115-125.
  35. Basha, O.M., R.A. Hafez, Y.M. El-Ayouty, K.F. Mahrous, M.H. Bareedy and A.M. Salama, 2008. C-Phycocyanin inhibits cell proliferation and may induce apoptosis in human hepg2 cells. Egypt J. Immunol., 15: 161-167.
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  36. Zoheir, K.M.A., A.S. Abdoon, K.F. Mahrous, M.A. Amer, M.M. Zaher, L.G. Yang and E.M. El-Nahass, 2007. Effects of season on the quality and in vitro maturation rate of Egyptian buffalo (Bubalus bubalis) oocytes. J. Cell Anim. Biol., 1: 29-33.
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  37. Mahrous, K.F., A.M.H. Salem, A.F. Hesseen, T.M. Mohamed, M.A.M. Ebrahim and L.M. Salem, 2007. Genetic diversity for milk yield genes in egyptian native cattle using microsatellite markers. Ain Shams Sci. Bull., 45: 27-42.
  38. Khalil, W.K.B., M.A. Mahmoud, M.M. Zahran and K.F. Mahrous, 2007. A sub-acute study of metronidazole toxicity assessed in Egyptian Tilapia zillii. J. Appl. Toxicol., 27: 380-390.
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  39. Marzouk, M.S., K.H. Zaghloul, K.F. Mahrous and M.I. Hanna, 2006. Genotoxic benzo(a) pyrene on the cultured orecochromis niloticus. J. Egypt. Soc.Toxicol., 34: 81-97.
  40. Mahrous, K.F., W.K.B. Khalil and M.A. Mahmoud, 2006. Assessment of toxicity and clastogenicity of sterigmatocystin in Egyptian Nile tilapia. Afr. J. Biotechnol., 5: 1180-1189.
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  41. Mahrous, K.F., A.S. Abdoon and A.M. Hassan, 2006. Cytological studies on egyptian dromedary camel. JASMR, 1: 28-39.
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  42. Mohamed, S.M., H.Z. Khalid, I.H. Magdy and F.M. Karima, 2005. The clinical signs, histopathological and physiological status associated with acute and chronic exposure to Benzo (A) pyrene in the cultured fish Oreochromis niloticus. J. Egypt. Ger. Soc. Zool., 47: 283-312.
  43. Mahrous, K.F., M. Abd-El Mordy, S.H. Abd El-Aziem and D.M. Hemdan, 2005. Genetic variations in one-humped camels present in Egypt. J. Genet. Eng. Biotechnol., 3: 15-29.
  44. Abu-Aita, N.A., H.H. Kamel and K.F. Mahrous, 2005. Cytogenetic and clinicopathologic changes associated with exposure of male baladi goat to low dose of organophosphorus pesticide selecron. Vet. Med. J., 53: 713-729.
  45. Abdel-Wahhab, M.A., A.M. Hassan, S.E. Aly and K.F. Mahrous, 2005. Adsorption of sterigmatocystin by montmorillonite and inhibition of its genotoxicity in the Nile tilapia fish (Oreachromis nilaticus). Mut. Res., 582: 20-27.
    PubMed  |  
  46. El-Aziem, S.H.A., M.A. Abdel-Wahab, A.M. Mahmoud, A.M. Hassan and F.M. Karima, 2004. Chemoprevention of barley and chemoprevention of barley and sage against acrylamide-induced genotoxic, biochemical and histopathological alterations in rats. Egypt. J. Hospital Med., 15: 40-56.
  47. Sekena, H., A. El Aziem, A.M. Hassan, H.A. Radwan and K.F. Mahrous, 2002. Genotoxicity of amaryl and diaben in mice. J. Egypt. Soc. ,Toxicol., 27: 31-38.
  48. Mahrous, K.F., S.A. El-Fiky, E. El-Nahass and A.M. Mahmoud, 2002. The protective effect of an isothiocyanate prodrug against chromosomal aberrations induced by some mutagenic drugs in mice. Arb.J. Biotecnol., 5: 121-134.
  49. Mahrous, K.F., M. El-Wardani and M.S. Hassanane, 2002. Chromosomal abnormalities in infertile buffalo with special focus on fragile sites. Egypt. J. Anim. Prod., 39: 75-85.
  50. Sokkar, S.M., A.M. Mahmoud and K.F. Mahrous, 2001. Histopathological and ultrastructural studies on melanomas in xiphophorus fish. Bull. Eur. Assoc. Fish Pathol., 21: 56-62.
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  51. Mahrous, K., S. EI-Fiky, S.A. El-Baset and O.A. EI-Monem, 2001. Mutagenic and teratogenic effects of indomethacin and cyclosporine-a on dams and fetuses of mice. Cytologia, 66: 1-9.
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  52. Mahrous, K. and H. Abdou, 2001. Cytogenetical studies on some Nile fish. J. Egypt. Ger. Soc. Zool., Histol. Histochem. Gen., 36: 133-144.
  53. Abul-Nasr, S.M., Karima and F. Mahrous, 2001. Cytogenetical studies of Garlic and it Significance for the protection against lead toxicity in Albino rats. Bull. NRC. Egypt., 26: 111-122.
  54. Abdoon, A.S.S., W. Mohiy and K.F. Mahrous, 2001. Effect of exposure to selecrone pesticide on ovulation rate, progesterone levels and chromosomal abnormalities in ewes. Vet. Med. J. Giza., 49: 5-15.
  55. Mahrous, K.F., M.M. Zahran, M.A. Mahmoud and S.M. Sokkar, 2000. Genetically studies on melanomas in xiphoporus fish. Arab J. Biotech., 4: 217-228.
  56. Mahrous, K. and S. Ahmed, 2000. Fragile sites in Egyptian water buffalo. Cytologia, 65: 313-317.
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  57. Mahrous, F., T.M. El-Sayed and I.A. Abd El-Hamid, 2000. Cytogenetic studies in relation to fertility in cattle. Vet. Med. J. Giza, 48: 35-45.
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  58. Klungland, H., H.G. Olsen, M.S. Hassanane, K.F. Mahrous and D.I. Vage, 2000. Coat color genes in cattle diversity studies. J. Anim. Breed. Genet., 117: 217-224.
  59. Karima, M.E.A., F.M. Malak, M. Zahran and A.H. Abo-Doma, 2000. Studies on inherent neural syndrome in rabbits. Egypt. J. Genet Cytol. Egypt., 29: 253-266.
  60. Hanafy, Z.E. and K.F. Mahrous, 2000. Influence of nigella sativa on paracetamol-induced genotoxicity in rats. J. Azhar. Med., 29: 217-228.
  61. Saleh, A.M., M.D. El-Shafey, K.F. Mahrous and M.H. Osfor, 1997. The role of Nigella Sativa (L) Oil in cadmium- induced toxicity in albino rats. J. Leg. Med. Forensic. Sci., 110: 221-251.
  62. Nasr, S.M.A., K.F. Mahrous, N.A. Kotb, S.A. Aggour, H.S. Bassiouni and A.F. Yousef, 1996. Effect of inhalation toxicity with a carbamate propoxur on chromosomal pattern of bone marrow cells in albino rats. MJFMCT, 3: 45-69.
  63. Mahrous, K.F., 1996. A case of mosaicism 60 XX/61,XXY in an hybrid friesian heifer. Egypt. J. Appl. Sci., 11: 45-52.
  64. Mahrous, K.F. and A.S.S. Abdoon, 1996. Relationship between superovulation and cytogenetical in buffaloes. Egypt J. Appl. Sci, 11: 213-225.
  65. Mahrous, K.F., I.M. Farag and M.I. Dessouky, 1995. Studies on chromosomal aberrations in a group of infertile horses. J. Egypt. Ger. Soc. Zool., 18: 33-43.
  66. Karima, F.M. and S.K. Inas, 1995. Cytogenetic effect of the antidiabetics metformin and tolbutamide and the antiinflammatory agent diclofenac sodium in rats. J. Egypt. Ger. Soc. Zool., 18: 219-231.
  67. Hassanane, M.S., K.F. Mahrous, A.S.S. Abdoon and F. Gadallah, 1995. A case report: Mosaic diploid/ tetraploid in a pregnant cow infected with lumby skin disease. Vet. Med. J. Giza, 43: 137-140.
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  68. Hassanane, M.S., A.S.S. Abdoon and K.F. Mahrous, 1995. Effect of hormonal treatments and cytogenetical aspects on ovarian function of Egyptian Baladi cattle heifers suffering from gonadal dysgenesis with special reference to serum progesterone levels. Vet. Med. J. Giza, 43: 257-264.
  69. Mahrous, K.F., M.S. Hassanane and A.F. El-Kholy, 1994. Robertsonian translocation and freemartin cases in hybrid Friesian cows raised in Egypt. Egypt. J. Anim. Prod., 31: 213-220.
  70. Emam, A.S., A.M. Deyab, K.F. Mahrous and S.A. Aggour, 1994. Cytogenetic effects of khat extract in albino rats. Egypt. J. Histol., 17: 109-122.
  71. Hondt, H.A., E. El‐Nahass and K. Fathy, 1988. Cytogenetic studies on Egyptian native cattle and some of its crossbreds. J. Anim. Breed. Genet., 105: 400-408.
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