Dr. Khairy AbdEl-Moneim Ibrahim
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Dr. Khairy AbdEl-Moneim Ibrahim

Associate Professor
Agriculture Research Center, Egypt

Highest Degree
Ph.D. in Biochemistry from Cairo University, Egypt

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Biography

Dr Khairy A. Ibrahim is currently a Researcher at Mammalian Toxicology department, Central Agricultural Pesticides Laboratory, Agricultural Research Center, Egypt. The team research work is focused mainly on understanding the mechanisms of Xenobiotic induced apoptosis with emphasis on environmental factors affection human risk. It includes Biochemistry, Basic Pharmacology, Physiology, Neurotoxicology, Immunotoxicology, and Toxicogenomics. He was published many manuscripts in experimental and food animals at many scientific journals related to Pharmacology, Toxicology, Biochemistry, Molecular Biology, and Clinical Pathology. Khairy is now a reviewer and an editorial member of many of the prestigious peer-reviewed journals.
Keywords: Pharmacology; Toxicology; Neurotoxicology; Pesticides; Alternative Medicine; Anti-inflammatory; Antioxidant.

Area of Interest:

Biomedical Sciences
100%
Human Anatomy
62%
Biochemical
90%
Toxicogenomics
75%
Physiological Mechanisms
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Ibrahim, K.A., H.A. Abdelgaid, M. Eleyan, R.A. Mohamed and N.M. Gamil, 2022. Resveratrol alleviates cardiac apoptosis following exposure to fenitrothion by modulating the sirtuin1/c-Jun N-terminal kinases/p53 pathway through pro-oxidant and inflammatory response improvements: In vivo and in silico studies. Life Sci., Vol. 290. 10.1016/j.lfs.2021.120265.
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  2. Abo Bakr, A., M. Ali and K. Ibrahim, 2022. Garlic and allopurinol alleviate the apoptotic pathway in rats’ brain following exposure to fipronil insecticide. Environ. Anal. Health Toxicol., Vol. 37. 10.5620/eaht.2022037.
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  3. Mohamed, A.A., K.A. Moneim, I.Y.A. Kader and A.R. Tawfik, 2021. Evaluation of nestin and reelin genes expression in the brain of hypothyroid neonatal rats treated with Emamectin benzoate during lactation period. Int. J. Pharm. Sci. Rev. Res., 67: 155-164.
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  4. Ibrahim, K.A., M. Eleyan, S.A. Khwanes, R.A. Mohamed and H.A.A. El-Rahman, 2021. Quercetin ameliorates the hepatic apoptosis of fetal rats induced by in utero exposure to fenitrothion via the transcriptional regulation of paraoxonase-1 and apoptosis-related genes. Biomarkers, 10.1080/1354750x.2021.1875505.
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  5. Ibrahim, K.A., M. Eleyan, S.A. Khwanes, R.A. Mohamed and B.M. Ayesh 2021. Alpha-Mangostin Attenuates the Apoptotic Pathway of Abamectin in the Fetal Rats’ Brain by Targeting Pro-Oxidant Stimulus, Catecholaminergic Neurotransmitters, and Transcriptional Regulation of Reelin and Nestin. Drug Chem. Toxicol. 10.1080/01480545.2021.1960856.
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  6. Ibrahim, K.A., H.A. Abdelgaid, M.A. Elu2010Desouky, A.A. Fahmi and M.M. Abdelu2010Daim, 2021. Linseed ameliorates renal apoptosis in rat fetuses induced by single or combined exposure to diesel nanoparticles or fenitrothion by inhibiting transcriptional activation of p21/p53 and caspaseu20103/9 through prou2010oxidant stimulus. Environ. Toxicol., 10.1002/tox.23097.
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  7. Ibrahim, K.A., H.A. Abdelgaid, M. Eleyan, S.A. Khwanes and M.M. Abdel-Daim, 2021. Ethoprophos induces rats` brain injury and neurobehavioral impairment via transcriptional activation of glial fibrillary acidic protein and tubulin-associated unit even at the threshold inhibition of acetylcholinesterase: a 90-days study. Sci. Total Environ., 10.1016/j.scitotenv.2021.146216.
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  8. El-Desouky, M.A., K.A. Ibrahim, A.A. Hanafy and D.S.S. El-Din, 2021. Amelioration of diabetic nephropathy with extracts of Pterocarpus santalinus heart wood and Brassica nigra seeds via regulation of insulin resistance and modulation of genes in streptozotocin induced diabetic rats. Medic. Plants Int. J. Phytomedicines Related Industries, 13: 99-109.
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  9. K.A. Ibrahim, M. Eleyan, H.Ali Abd El-Rahman, S.A. Khwanes and R. A. Mohamed, 2020. Quercetin Attenuates the Oxidative Injury–Mediated Upregulation of Apoptotic Gene Expression and Catecholaminergic Neurotransmitters of the Fetal Rats’ Brain Following Prenatal Exposure to Fenitrothion Insecticide Neurotox. Res., 37: 871-882.
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  10. K. A. El-Moneim Ibrahim, S.M.Abdelrahman, H. K. A. Elhakim and Eman Ali Ragab, 2020. Single or combined exposure to chlorpyrifos and cypermethrin provoke oxidative stress and downregulation in monoamine oxidase and acetylcholinesterase gene expression of the rat’s brain. Environ. Sci. Pollut. Res., 27: 12692-12703.
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  11. Ibrahim, K.A., H.A. Abdelgaid, M.A. El-Desouky, A.A. Fahmi and M.M. Abdel-Daim, 2020. Modulation of paraoxonase-1 and apoptotic gene expression involves in the cardioprotective role of flaxseed following gestational exposure to diesel exhaust particles and/or fenitrothion insecticide. Cardiovasc. Toxicol., 10.1007/s12012-020-09585-3.
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  12. Sayed, A.A., M.A. El-Desouky and K.A. Ibrahim, 2019. Garlic and allopurinol attenuate hepatic apoptosis induced by fipronil in male albino rats. Regulatory Toxicol. Pharmacol., 107: 104400-104400.
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  13. Ibrahim, K.A., S.A. Khwanes, M.A. El-Desouky and H.K.A. Elhakim, 2019. Propolis relieves the cardiotoxicity of chlorpyrifos in diabetic rats via alleviations of paraoxonase-1 and xanthine oxidase genes expression. Pesticide Biochem. Physiol., 159: 127-135.
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  14. AlBasher, G., M.M. Abdel-Daim, R. Almeer, K.A. Ibrahim, R.Z. Hamza, S. Bungau and L. Aleya, 2019. Synergistic antioxidant effects of resveratrol and curcumin against fipronil-triggered oxidative damage in male albino rats. Environ. Sci. Pollut. Res., 27: 6505-6514.
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  15. Ibrahim, K.A., M. Eleyan, M.A. El-Desouky, H.A. Daboun and H.A. Abd El Rahman, 2018. The potential protective role of quercetin against nano-rich diesel exhaust particles induce hepatic apoptosis in albino rat fetuses. J. Chem. Pharm. Res., 10: 121-128.
  16. Ibrahim, K.A. and S.A. Khwanes, 2018. The protective role of propolis against chlorpyrifos induced oxidative stress and DNA damage in the liver of male albino rats. Egypt. J. Agric. Res., 96: 85-94.
  17. Fahmi, A.A., M.A. El-Desouky, K.A. Ibrahim and H.A. Abdelgaid, 2018. Flaxseed alleviates toxic effects of some environmental pollutants on pregnant rats and their foetuses. Biosci. Res., 15: 1832-1844.
  18. Eleyan, M., M.A. El-Desouky, K.A. Ibrahim, H.A. Daboun and H.A. Abd El Rahman, 2018. Quercetin alleviates the adverse effects of nano-rich diesel exhaust particles on pregnancy and fetal growth in rats. Biosci. Res., 15: 4590-4602.
  19. Eleyan, M., M.A. El-Desouky, K.A. Ibrahim and H.A. Daboun, 2018. Quercetin suppresses apoptotic genes expression and DNA fragmentation induced by nano-rich diesel exhaust particles in the fetal brain. Merit Res. J. Med. Med. Sci., 6: 257-264.
  20. Hasani, I.W., M.A. El-Desouky, N.E. Sharaf, A.A. Abdel Shakour, Y.A. Fahim, K.A. Ibrahim and M. Elhamshary, 2016. Lead and cadmium induce chromosomal aberrations and DNA damage among foundry workers. J. Chem. Pharm. Res., 8: 652-661.
  21. Ibrahim, K.A., M.A. El-Desouky, H.M. Abou-Yousef, K.H. Gabrowny and A.S.M. El-Sayed, 2015. Imidacloprid and/or esfenvalerate induce apoptosis and disrupt thyroid hormones in neonatal rats. Global J. Biotechnol. Biochem., 10: 106-112.
  22. Gabrowny, K.H., S.M. Sherif, A.I. Amin and K.A. Ibrahim, 2012. The impact of thyroid hormones and caspase-3 in Cypermethrin and/or Diazinon inducedapoptosis in neonate rats Brain. Egypt. J. Forensic Sci. Applied Toxicol., 12: 79-98.
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