Dr. Olfat Gamil Shaker
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Dr. Olfat Gamil Shaker

Biochemistry
Ain Shams University, Cairo, Egypt

Highest Degree
M.D. in Biochemistry from Cairo University, Egypt

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Area of Interest:

Biomedical Sciences
100%
Biochemistry
62%
Molecular Biology
90%
Medicine
75%
Polymorphism
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
329
Abstracts
0

Selected Publications

  1. Shaker, O.G., S.R. Mohammed, A.M. Mohammed and Z. Mahmoud, 2018. Impact of microRNA‐375 and its target gene SMAD‐7 polymorphism on susceptibility of colorectal cancer. J. Clin. Lab. Anal., Vol. 32. 10.1002/jcla.22215.
    CrossRef  |  Direct Link  |  
  2. Shaker, O.G., N.A.E. Boghdady and A.E.D. El Sayed, 2018. Association of MiRNA-146a, MiRNA-499, IRAK1 and PADI4 polymorphisms with rheumatoid arthritis in Egyptian population. Cel. Physiol. Biochem., 46: 2239-2249.
    CrossRef  |  Direct Link  |  
  3. Shaker, O.G. and H.S. Helmy, 2018. Circulating bone-related markers and YKL-40 versus HER2 and TOPO2a in bone metastatic and nonmetastatic breast cancer: Diagnostic implications. Clin. Breast Cancer, 18: e321-e328.
    CrossRef  |  Direct Link  |  
  4. Kasem, R.F., D.S. Khater, G.A. Abdel-Latif and O.G. Shaker, 2018. Expression of miR-34a/p53 and their apoptotic target bax in oral squamous cell carcinoma. Int. J. Cancer Res., 114: 32-38.
    CrossRef  |  Direct Link  |  
  5. Haroun, H.S.W., O.G. Shaker, M.K.A. El-Wahed, T.I.A. El-Galil and E.A. Abdein, 2018. Bone marrow-derived mesenchymal stem cells attenuate the subchronic adverse effect of lead acetate on the kidney of adult albino rat. J. Adv. Pharm. Edu. Res., 8: 45-52.
    Direct Link  |  
  6. Esmat, S.M., H.H. El Hadidi, R.A. Hegazy, H.I. Gawdat and A.M. Tawdy et al., 2018. Increased tenascin C and DKK1 in vitiligo: Possible role of fibroblasts in acral and non-acral disease. Arch. Dermatol. Res., 310: 425-430.
    CrossRef  |  Direct Link  |  
  7. El-Koofy, N., H.M. Fouad, M.E. Fahmy, H. Helmy, O. Shaker, H.M. El-Karaksy and N. Mohsen, 2018. Copper concentrations in Egyptian infants with cholestasis: A single center study. Arab J. Gastroenterol., 19: 21-25.
    CrossRef  |  Direct Link  |  
  8. El Tahlawi, S.M., N.H. El Eishi, R.K. Kahhal, R.A. Hegazy, G.M. El Hanafy, R.M.A. Hay and O.G. Shaker, 2018. Do prolactin and its receptor play a role in alopecia areata?. Indian J. Dermatol., 63: 241-245.
    CrossRef  |  Direct Link  |  
  9. Ayeldeen, G., Y. Nassar, H. Ahmed, O. Shaker and T. Gheita, 2018. Possible use of miRNAs-146a and -499 expression and their polymorphisms as diagnostic markers for rheumatoid arthritis. Mol. Cell. Biochem., 2018: 1-12.
    Direct Link  |  
  10. Aghbari, S.M.H., S.M. Gaafar, O.G. Shaker, S. El Ashiry and S.O. Zayed, 2018. Evaluating the accuracy of microRNA27b and microRNA137 as biomarkers of activity and potential malignant transformation in oral lichen planus patients. Arch. Dermatol. Res., 310: 209-220.
    CrossRef  |  Direct Link  |  
  11. Aghbari, S.M.H., A.I. Abushouk, O.G. Shakir, S.O. Zayed and A. Attia, 2018. Correlation between tissue expression of microRNA-137 and CD8 in oral lichen planus. Clin. Oral Invest., 22: 1463-1467.
    CrossRef  |  Direct Link  |  
  12. Youssef, R.M., N.A. Dorgham, R.A. Hegazy, O. Shaker and S. Kotb, 2017. Estimation of calcidiol level in serum of atopic dermatitis patients before and after NB-UVB phototherapy in comparison to oral vitamin D therapy. J. Clin. Exp. Dermatol. Res., Vol. 8. 10.4172/2155-9554.1000417.
    CrossRef  |  Direct Link  |  
  13. Yosry, A., D. Omran, M. Yousef, M. Salah and H. Omar et al., 2017. SNPs in the insulin-like growth factor gene and obesity impact on colorectal cancer in Egyptians. Asian Pac. J. Cancer Prev., 18: 2959-2964.
    CrossRef  |  Direct Link  |  
  14. Shaker, O.G., M.S. Wadie, R.M.M. Ali and A. Yosry, 2017. SIRT1 gene polymorphisms and its protein level in colorectal cancer. Gene Rep., 7: 164-168.
    CrossRef  |  Direct Link  |  
  15. Shaker, O.G., M.A. Senousy and E.M. Elbaz, 2017. Association of rs6983267 at 8q24, HULC rs7763881 polymorphisms and serum lncRNAs CCAT2 and HULC with colorectal cancer in Egyptian patients. Sci. Rep., Vol. 7 10.1038/s41598-017-16500-4.
    CrossRef  |  Direct Link  |  
  16. Shaker, O.G. and M.A. Senousy, 2017. Serum microRNAs as predictors for liver fibrosis staging in hepatitis C virus‐associated chronic liver disease patients. J. Viral Hepatitis, 24: 636-644.
    CrossRef  |  Direct Link  |  
  17. Shaker, O., S. Omran, E. Sharaf, G.A. Hegazy, M. Mashaly and N.E. Gaboon, 2017. A novel mutation in exon 1 of GATA4 in Egyptian patients with congenital heart disease. Turk. J. Med. Sci., 47: 217-221.
    CrossRef  |  Direct Link  |  
  18. Shaker, O., M. Alhelf, G. Morcos and A. Elsharkawy, 2017. miRNA-101-1 and miRNA-221 expressions and their polymorphisms as biomarkers for early diagnosis of hepatocellular carcinoma. Infect. Genet. Evol., 51: 173-181.
    CrossRef  |  Direct Link  |  
  19. Sadik, N.A.H., N.S. Metwally, O.G. Shaker, M.S. Soliman, A.A. Mohamed and M. Abdelmoaty, 2017. Local renin-angiotensin system regulates the differentiation of mesenchymal stem cells into insulin-producing cells through angiotensin type 2 receptor. Biochimie, 137: 132-138.
    CrossRef  |  Direct Link  |  
  20. Motawi, T.K., O.G. Shaker, M.F. Ismail and N.H. Sayed, 2017. Peroxisome proliferator-activated receptor gamma in obesity and colorectal cancer: The role of epigenetics. Sci. Rep., Vol. 7. 10.1038/s41598-017-11180-6.
    CrossRef  |  Direct Link  |  
  21. Monir, A., El-Ganzuri, O.G. Shaker, N.M. Kassem and L.L. Nazmi, 2017. The effect of human umbilical cord blood mesenchymal stem cells on the expression of leukaemic inhibitory factor (LIF) and interleukin-10 (Il-10) in acute myeloid leukaemia (AML). Sch. Acad. J. Biosci., 5: 723-731.
  22. Labib, D.A.A., W.Y. Abdelzaher, O.G. Shaker and L.O. Elfarouk, 2017. Evaluation of the colo-protective effects of tadalafil in an experimental model of ulcerative colitis in rats. Afr. J. Pharm. Pharmacol., 11: 385-393.
    CrossRef  |  Direct Link  |  
  23. Ghallab, N.A., R.F. Kasem, S.F.A. El-Ghani and O.G. Shaker, 2017. Gene expression of miRNA-138 and cyclin D1 in oral lichen planus. Clin. Oral Invest., 21: 2481-2491.
    CrossRef  |  Direct Link  |  
  24. Ghallab, N.A. and O.G. Shaker, 2017. Serum and salivary levels of chemerin and MMP-9 in oral squamous cell carcinoma and oral premalignant lesions. Clin. Oral Invest., 21: 937-947.
    CrossRef  |  Direct Link  |  
  25. Elshafei, A., O. Shaker, O. Abd El-motaal and T. Salman, 2017. The expression profiling of serum miR-92a, miR-375 and miR-760 in colorectal cancer: An Egyptian study. Tumor Biol., Vol. 39. 10.1177/1010428317705765.
    CrossRef  |  Direct Link  |  
  26. Elhefny, R.A., M.M. Shaban and O.G. Shaker, 2017. Prognostic value of pro‐inflammatory cytokine and pro‐angiogenesis factor in differentiating malignant from benign exudative effusion. Clin. Respir. J., 11: 49-57.
    CrossRef  |  Direct Link  |  
  27. El Mofty, M., S. Esmat, N. Hunter, H.M. Mashaly, D. Dorgham, O. Shaker and S. Ibrahim, 2017. Effect of different types of therapeutic trauma on vitiligo lesions. Dermatol. Ther., Vol. 30. 10.1111/dth.12447.
    CrossRef  |  Direct Link  |  
  28. Alkadasi, B., S. Abdulrab, S. Gaafer, B. Kalakonda, M. Hosny, O. Shaker and M. Hosny, 2017. Effect of adjunctive use of systemic antioxidant therapy (N-acetylcysteine) on soluble receptor activator nuclear factor κB ligand levels in gingival crevicular fluid following surgical periodontal treatment for chronic periodontitis. J. Oral Sci., 59: 519-526.
    CrossRef  |  Direct Link  |  
  29. Al-Nahas, Z., M. Fawzy, M. El Menyawi, O. Shaker and G. Ragab, 2017. 25-hydroxyvitamin D3 deficiency and vitamin D receptor polymorphisms in Egyptian patients with Behcet’s disease: A pilot study. Int. J. Clin. Rheumatol., 12: 20-27.
    Direct Link  |  
  30. Abdul-Aziz, M.A., A.K. Amin, D.H. El-Rouby and O.G. Shaker, 2017. Lymphangiogenesis in oral squamous cell carcinoma: Correlation with VEGF-C expression and lymph node metastasis. Int. J. Dent., Vol. 2017. 10.1155/2017/7285656.
    CrossRef  |  Direct Link  |  
  31. Zalata, A.A., N. Mokhtar, A. Atwa, M. Khaled and O.G. Shaker, 2016. The role of protamine 2 gene expression and caspase 9 activity in male infertility. J. Urol., 195: 796-800.
    CrossRef  |  Direct Link  |  
  32. Youssef, R., S. Ossama, H.M. Mashaly, M. Fathy, M. Safwat, O. Shaker and M. El-Mofty, 2016. Phototherapeutic modalities pose no significantly increased risk of oxidative damage to DNA in dark skinned individuals. Indian J. Dermatol. Venereol. Leprol., 82: 666-672.
    CrossRef  |  Direct Link  |  
  33. Tomerak, R.H., N.F. Helal, O.G. Shaker and M.A. Yousef, 2016. Association between the specific UGT1A1 promoter sequence variant (c-3279T>G) and unconjugated neonatal hyperbilirubinemia. J. Trop. Pediatr., 62: 457-463.
    CrossRef  |  Direct Link  |  
  34. Shaker, O.G., S.M.R. Eltahlawi, S.O. Tawfic, A.M. Eltawdy and N.I.E. Bedair, 2016. Corticotropin‐releasing hormone (CRH) and CRH receptor 1 gene expression in vitiligo. Clin. Exp. Dermatol., 41: 734-740.
    CrossRef  |  Direct Link  |  
  35. Shaker, O.G., H.H. El-Demellawy, M.N. Salem and N.N. Eesa, 2016. Methylene tetrahydrofolate reductase (MTHFR) gene polymorphisms in rheumatoid arthritis patients: Correlation with serum osteopontin levels and disease activity. Egypt. Rheumatol., 38: 283-288.
    CrossRef  |  Direct Link  |  
  36. Shaker, O.G., A.M. Alnoury, G.A. Hegazy, H.E. El Haddad, S. Sayed and A. Hamdy, 2016. Methylene tetrahydrofolate reductase, transforming growth factor-β1 and lymphotoxin-α genes polymorphisms and susceptibility to rheumatoid arthritis. Rev. Bras. Reumatol., 56: 414-420.
    CrossRef  |  Direct Link  |  
  37. Shahin, W.A., I.E.A. Meguid, K. Elhamamsy and O.G. Shaker, 2016. IL6-174 G/C gene polymorphism in children with septicemia: Single center study. J. Pediatr. Neonatal Care, Vol. 4. 10.15406/jpnc.2016.04.00156.
    CrossRef  |  Direct Link  |  
  38. Shahin, A.A., O.G. Shaker, H.E. Darweesh, M. El Sayed and B.M. Ali, 2016. Does human leukocyte antigen influence the risk of development and type of vasculitis in Egyptian patients with chronic hepatitis C virus infection?. Egypt. Rheumatol., 38: 307-312.
    CrossRef  |  Direct Link  |  
  39. Rizk, S.M., N.N. Shahin and O.G. Shaker, 2016. Association between SIRT1 gene polymorphisms and breast cancer in Egyptians. PLoS One, Vol. 11. 10.1371/journal.pone.0151901.
    CrossRef  |  Direct Link  |  
  40. Rasheed, H., M.H.M. El-Komy, R.A. Hegazy, H.I. Gawdat, A.M. AlOrbani and O.G. Shaker, 2016. Expression of sirtuins 1, 6, tumor necrosis factor, and interferon-γ in psoriatic patients. Int. J. Immunopathol. Pharmacol., 29: 764-768.
    CrossRef  |  Direct Link  |  
  41. Othman, N.A., O.G. Shaker, H.M. Elshenawy, W. Abd-Elmoniem, A.M. Eldin and M.Y. Fakhr, 2016. The effect of diode laser and topical steroid on serum level of TNF-alpha in oral lichen planus patients. J. Clin. Exp. Dent., 8: e566-e570.
    CrossRef  |  Direct Link  |  
  42. Motawi, T.M.K., N.A.H. Sadik, O.G. Shaker, M.R. El Masry and F. Mohareb, 2016. Study of microRNAs-21/221 as potential breast cancer biomarkers in Egyptian women. Gene, 590: 210-219.
    CrossRef  |  Direct Link  |  
  43. Motawi, T.M., N.A. Sadik, O.G. Shaker and M.H. Ghaleb, 2016. Elevated serum microRNA-122/222 levels are potential diagnostic biomarkers in Egyptian patients with chronic hepatitis C but not hepatic cancer. Tumor Biol., 37: 9865-9874.
    CrossRef  |  Direct Link  |  
  44. Motawi, T.K., O.G. Shaker, N.N. Shahin, H.M. Kamalaldin and N.M. Ahmed, 2016. Leptin as a possible link between obesity, hypertension and insulin resistance in Egyptian females. Int. J. Adv. Res., 4: 636-644.
  45. Motawi, T.K., O.G. Shaker, N.N. Shahin and N.M. Ahmed, 2016. Angiotensin-converting enzyme insertion/deletion polymorphism association with obesity and some related disorders in Egyptian females: A case-control observational study. Nutr. Metab., Vo. 13. 10.1186/s12986-016-0127-5.
    CrossRef  |  Direct Link  |  
  46. Motawi, T., O.G. Shaker, R.M. Hussein and M. Houssen, 2016. Polymorphisms of α1-antitrypsin and Interleukin-6 genes and the progression of hepatic cirrhosis in patients with a hepatitis C virus infection. Balkan J. Med Genet., 19: 35-44.
    CrossRef  |  Direct Link  |  
  47. Malak, C.A.A., O.G. Shaker, E. Ashour and L. Magdy, 2016. Genetic variations of the TNF-α-308 G> A promoter and TGF-β1 T869C polymorphisms in Egyptian patients with rheumatoid arthritis. Int. J. Clin. Exp. Pathol., 9: 9786-9797.
    Direct Link  |  
  48. Khairy, A., I. Hamza, O. Shaker and A. Yosry, 2016. Serum miRNA panel in Egyptian patients with chronic hepatitis C related hepatocellular carcinoma. Asian Pac. J. Cancer Prev., 17: 2699-2703.
    PubMed  |  Direct Link  |  
  49. Ghallab, N.A., E. Hamdy and O.G. Shaker, 2016. Malondialdehyde, superoxide dismutase and melatonin levels in gingival crevicular fluid of aggressive and chronic periodontitis patients. Aust. Dent. J., 61: 53-61.
    CrossRef  |  Direct Link  |  
  50. Fawzi, M.M., S.B. Mahmoud, S.F. Ahmed and O.G. Shaker, 2016. Assessment of vitamin D receptors in alopecia areata and androgenetic alopecia. J. Cosmet. Dermatol., 15: 318-323.
    CrossRef  |  Direct Link  |  
  51. Fawzi, M.M., S.B. Mahmoud, O.G. Shaker and M.A. Saleh, 2016. Assessment of tissue levels of dickkopf‐1 in androgenetic alopecia and alopecia areata. J. Cosmet. Dermatol., 15: 10-15.
    CrossRef  |  Direct Link  |  
  52. Eslam, M., A.M. Hashem, M. Romero-Gomez, T. Berg and G.J. Dore et al., 2016. FibroGENE: A gene-based model for staging liver fibrosis. J. Hepatol., 64: 390-398.
    CrossRef  |  Direct Link  |  
  53. Emam, A.M., G.S. Georgy, O.G. Shaker, H.M. Fawzy and H.F. Zaki, 2016. Protective effects of alpha-lipoic acid and coenzyme Q10 on lipopolysaccharide-induced liver injury in rats. Der Pharmacia Lett., 8: 176-182.
    Direct Link  |  
  54. Elela, M.A., H.I. Gawdat, R.A. Hegazy, M.M. Fawzy, R.M.A. Hay, D. Saadi and O. Shaker, 2016. B cell activating factor and T-helper 17 cells: Possible synergistic culprits in the pathogenesis of alopecia areata. Arch. Dermatol. Res., 308: 115-121.
    CrossRef  |  Direct Link  |  
  55. El-Ramly, A.Z., M.M. Fawzi, S.B. Mahmoud, M.M. Abdel Ghaffar and O.G. Shaker, 2016. Assessment of serum levels of cathelicidin and vitamin D in acne vulgaris. J. Egypt. Women's Dermatol. Soc., 13: 99-105.
    CrossRef  |  Direct Link  |  
  56. El-Kady, M.M., Z.I. Girgis, E.A.A. El-Rasheed, O. Shaker, M.I. Attallah and A.A. Soliman, 2016. Role of selective blocking of bradykinin receptor subtypes in attenuating allergic airway inflammation in guinea pigs. Eur. J. Pharmacol., 788: 152-159.
    CrossRef  |  Direct Link  |  
  57. El-Fattah, A.A.A., N.A.H. Sadik, O.G. Shaker and A.M. Kamal, 2016. Are SMAD7 rs4939827 and CHI3L1 rs4950928 polymorphisms associated with colorectal cancer in Egyptian patients?. Tumor Biol., 37: 9387-9397.
    CrossRef  |  Direct Link  |  
  58. El Mofty, M., S. Essmat, R. Youssef, S. Sobeih and D. Mahgoub et al., 2016. The role of systemic steroids and phototherapy in the treatment of stable vitiligo: A randomized controlled trial. Dermatologic Ther., 29: 406-412.
    CrossRef  |  Direct Link  |  
  59. Alnory, A., H. Gad, G. Hegazy and O. Shaker, 2016. The association of vaspin rs2236242 and leptin rs7799039 polymorphism with metabolic syndrome in Egyptian women. Turk. J. Med. Sci., 46: 1335-1340.
    CrossRef  |  Direct Link  |  
  60. Ahmed, E., B. Mostafa, A. Maged and O. Shaker, 2016. Evaluation of the effect of diacerein on IL-1β and osteocalcin levels in GCF of chronic periodontitis patients: A non-randomized controlled clinical trial. J. Int. Dent. Med. Res., 9: 98-107.
    Direct Link  |  
  61. Abdelbadiaa, M., O.G. Shaker, H.N. Hosni, S.E. Khalifa and A.F. Shazly, 2016. Human papillomavirus (HPV) in Egyptian females: Study by cytology, histopathology, colposcopy and molecular diagnosis of high risk types. Malays. J. Pathol., 38: 257-266.
    Direct Link  |  
  62. Zahran, F., D. Ghalwash, O. Shaker, K. Al-Johani and C. Scully, 2015. Salivary microRNAs in oral cancer. Oral Dis., 21: 739-747.
    CrossRef  |  Direct Link  |  
  63. Shaker, O.G., M.T. Abdel-Rahim and S.T. Bayoumi, 2015. Gene polymorphisms of IL-10 and MxA in responders and non-responders to interferon therapy in HCV Egyptian patients genotype 4. Cell Biochem. Biophys., 71: 617-625.
    CrossRef  |  Direct Link  |  
  64. Shaker, O.G., A.R. Elshehaby, A.A. Zahra, O.O. Abdelaleem and A. Yousry, 2015. Circulating microRNAs, miR-122, miR148a and 194b in patients with HCC emerging from chronic HCV infection background. Med. J. Cairo Univ., 83: 805-810.
    Direct Link  |  
  65. Shaker, O.G. and N. Abdelhamid, 2015. Detection of enteroviruses in pediatric patients with aseptic meningitis. Clin. Neurol. Neurosurg., 129: 67-71.
    CrossRef  |  Direct Link  |  
  66. Shaker, O., M.A. Abdelhafez, S. Fayez and Y.M. Alsherif, 2015. Phosphatidylinositol 3-kinase and insulin receptor substrate-1 gene polymorphism/adipocytokines interaction in pathogenesis of insulin resistance among Egyptian patients: A pilot study. Int. J. Res. Stud. Biosci., 3: 81-93.
  67. Shaker, O., M. Maher, Y. Nassar, G. Morcos and Z. Gad, 2015. Role of microRNAs -29b-2, -155, -197 and -205 as diagnostic biomarkers in serum of breast cancer females. Gene, 560: 77-82.
  68. Shaker, O., F. Taha, M. Salah and M. El-Marzouky, 2015. LAPTM4B gene expression and polymorphism as diagnostic markers of breast cancer in Egyptian patients. J. Med. Biochem., 34: 393-401.
    CrossRef  |  Direct Link  |  
  69. Shaker, O., A. Rashad, G.A. Aziz and M.E. Raziky, 2015. Is rs8099917 polymorphism of IL-28B gene a good predictor of response to therapy of hcv than rs12979860? an egyptian study. Cell Biochem. Biophys., 71: 307-314.
    CrossRef  |  Direct Link  |  
  70. Shaker, O., A. Elshehaby, A. Zahra, O. Abdelaleem and A. Yousry, 2015. Hepatocyte derived microRNAs as serum predictors of rejection of liver transplantation. Med. J. Cairo Univ., 83: 103-108.
  71. Sadik, N.A., O.G. Shaker, H.Z. Ghanem, H.A. Hassan and A.Z. Abdel-Hamid, 2015. Single-nucleotide polymorphism of Toll-like receptor 4 and interleukin-10 in response to interferon-based therapy in Egyptian chronic hepatitis C patients. Arch Virol., 160: 2181-2195.
    CrossRef  |  Direct Link  |  
  72. Saad, M.N., M.S. Mabrouk, A.M. Eldeib and O.G. Shaker, 2015. Genetic case-control study for eight polymorphisms associated with rheumatoid arthritis. PLoS One, Vol. 10. 10.1371/journal.pone.0131960.
    CrossRef  |  Direct Link  |  
  73. Saad, M.N., M.S. Mabrouk, A.M. Eldeib and O.G. Shaker, 2015. Effect of MTHFR, TGFβ1 and TNFB polymorphisms on osteoporosis in rheumatoid arthritis patients. Gene, 568: 124-128.
    CrossRef  |  Direct Link  |  
  74. Roshdy, A., H. Okash, A. Soliman, H. Maamoun, O. Shaker, M.A. Soliman and A. Hamdy, 2015. Serum fetuin a levels: Are they a reliable marker for hepatic steatosis and regional adiposity in renal transplant recipients? Transplant Proc., 47: 2703-2706.
    CrossRef  |  Direct Link  |  
  75. Ramzy, I., M. Hasaballah, R. Marzaban, O. Shaker and Z.A. Soliman, 2015. Evaluation of microRNAs-29a, 92a and 145 in colorectal carcinoma as candidate diagnostic markers: An Egyptian pilot study. Clinics Res. Hepatol. Gastroenterol., 39: 508-515.
    CrossRef  |  Direct Link  |  
  76. Osman, W.A., S.A. Elmessiry, O. Shaker, I.M. Zaki, M.Y. Wissa and M.S. Amer and A.A. Shamaa, 2015. Comparative study of the effect of diacerein and diclofenac sodium and their combination in osteoarthritis model induced by monoiodoacetate in albino rats. Res. J. Pharm. Biol. Chem. Sci., 6: 1079-1089.
  77. Omar, H.S., O.G. Shaker, Y.H. Nassar, S.A. Marzouk and M.S.E. Marzouky, 2015. The association between RANKL and Osteoprotegerin gene polymorphisms with breast cancer. Mol. Cell Biochem., 403: 219-229.
    CrossRef  |  Direct Link  |  
  78. Motawi1, T.K., O.G. Shaker, S.A. El-Maraghy and M.A. Senousy, 2015. Serum interferon-related MicroRNAs as biomarkers to predict the response to interferon therapy in chronic hepatitis C genotype 4. PLoS One, Vol. 10. 10.1371/journal.pone.0120794.
    CrossRef  |  Direct Link  |  
  79. Motawi, T.M.K., S.M. Rizk, O.G. Shaker and O.Z.H. Mokhtar, 2015. MicroRNAs as predictor markers for response to interferon treatment of chronic hepatitis C genotype-4 in Egyptian patients. PLoS One. Vol. 10. 10.1371/journal.pone.0121524.
    CrossRef  |  Direct Link  |  
  80. Motawi, T.K., O.G. Shaker, S.A. El-Maraghy and M.A. Senousy, 2015. Serum micrornas as potential biomarkers for early diagnosis of hepatitis C virus-related hepatocellular carcinoma in egyptian patients. PLoS One, Vol. 10. 10.1371/journal.pone.0137706.
    CrossRef  |  Direct Link  |  
  81. Motawi, T., T. Salman, O. Shaker and A. Abdelhamid, 2015. Association of polymorphism in adiponectin (+45 T/G) and leptin (–2548 G/A) genes with type 2 diabetes mellitus in male Egyptians. Arch. Med. Sci., 11: 937-944.
    CrossRef  |  Direct Link  |  
  82. Mohamed, A.A., W.G. Shousha, O. Shaker, M.M. El-Sayed and E.M.A. Ibrahim et al., 2015. Insulin resistance in Egyptian nonalcoholic fatty liver disease patients. Br. J. Med. Med. Res., 6: 463-473.
    CrossRef  |  
  83. Heba Ayeldeen, Olfat Shaker, Osman Hegazy and Aboul Ella Hassanien, 2015. Distance similarity as a CBR technique for early detection of breast cancer: An Egyptian case study. Inf. Syst. Des. Intell. Appl., 340: 449-456.
    CrossRef  |  Direct Link  |  
  84. Hassan, S.H.S., M.I. El-Refai, N.A. Ghallab, R.F. Kasem and O.G. Shaker, 2015. Effect of periodontal surgery on osteoprotegerin levels in gingival crevicular fluid, saliva, and gingival tissues of chronic periodontitis patients. Dis. Markers, Vol. 2015. 10.1155/2015/341259.
    CrossRef  |  Direct Link  |  
  85. Hafez, V.G., M. Bosseila, M.T.A. Halim, O.G. Shaker, M. Kamal, H.S. Kareem, 2015. Clinical effects of "pioglitazone", an insulin sensitizing drug, on psoriasis vulgaris and its co-morbidities, a double blinded randomized controlled trialx1. J. Dermatol. Treat, 26: 208-214.
    CrossRef  |  Direct Link  |  
  86. Gheita, T.A., S.M. Gamal, I. Shaker, H.S.E. Fishawy, R.E. Sisi, O.G. Shaker and S.A. Kenawy, 2015. Clinical significance of serum interleukin-23 and A/G gene (rs17375018) polymorphism in Behçets disease: Relation to neuro-Behçet, uveitis and disease activity. Joint Bone Spine, 82: 213-215.
  87. Ghallab, N.A., E.M. Amr and O.G. Shaker, 2015. Expression of leptin and visfatin in gingival tissues of chronic periodontitis with and without type 2 diabetes mellitus: A study using enzyme-linked immunosorbent assay and real-time polymerase chain reaction. J. Periodontol., 86: 882-889.
    CrossRef  |  Direct Link  |  
  88. Eslam, M., A.M. Hashem, R. Leung, M. Romero-Gomez and T. Berg et al., 2015. Interferon-λ rs12979860 genotype and liver fibrosis in viral and non-viral chronic liver disease. Nat. Commun., Vol. 6. 10.1038/ncomms7422.
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  89. El-Komy, M.H., S.B. Mahmoud, M.M. Abdelhady and O.G. Shaker, 2015. Human β-defensin-2 expression in the scales of pityriasis versicolor and psoriasis. J. Egypt. Women’s Dermatol. Soc., 12: 170-173.
    CrossRef  |  Direct Link  |  
  90. Borai, I.H., O.G. Shaker, N.S. Hassan, E.A. Mohammed, E. Badrawy, O.M. Fawzy and L. Mageed, 2015. Evaluation of serum interleukin-6 levels and lipid profile as biomarkers in egyptian patients with atherosclerotic coronary artery disease. Adv. Environ. Biol., 9: 21-27.
    Direct Link  |  
  91. Ayeldeen, H., O. Shaker, O. Hegazy and A.E. Hassanien, 2015. Case-based reasoning: A knowledge extraction tool to use. Inf. Syst. Des. Intell. Appl., 339: 369-378.
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  92. Amin, M.A., K. Ashmawi, O. Shakr, S. Mussa, R.M.A. Samie and A. Hamdy, 2015. Serum adipokines in patients with non-alcoholic fatty liver disease - is there a role for predicting the severity of liver disease? Int. Med., Vol. 5. 10.4172/2165-8048.1000191.
    CrossRef  |  
  93. Abdel-Hamid, M., O.G. Shaker, D. El-Sayedellakwa and E.F. Abdel-Maksoud, 2015. Detection of BCL2 polymorphism in patient with hepatocellular carcinoma. Am. J. Cancer Prev., 3: 27-34.
    CrossRef  |  Direct Link  |  
  94. Abd-Rabou, A.A., E.F. Eskander, M.S. Mohamed, S.M. Yahya, A. El Sherbini and O.G. Shaker, 2015. P53 rs1042522 and CD95 rs1800682 genetic variations in HCV-4a response to antiviral therapy. Genes Dis., 2: 197-210.
    CrossRef  |  Direct Link  |  
  95. Tawfic, S.O., M.R.E. Abdel-Halim and O.G. Shaker, 2014. Assessment of interleukin-17 in alopecia areata: A case-control pilot study. J. Egypt. Women's Dermatol. Soc., 11: 20-23.
    CrossRef  |  Direct Link  |  
  96. Sherif, H., N.K.M. Khalil, M.A. Radwan, O.G. Shaker and H. Mourad, 2014. Relation of vitamin D concentration with macrovascular and microvascular complications type 2 diabetes mellitus in Egyptians. Int. J. Acad. Res. Part A, 6: 108-117.
    CrossRef  |  
  97. Shaker. O.G., Y.H. Nassar, M.M. Kamel, Z.S. Gad and A.M. Elantably, 2014. Chitinase-3-like protein1 (YKL-40) as biomarker in serum of Egyptian breast cancer females. Biochem. Anal. Biochem., 3: 1-6.
  98. Shaker, O.G., S.O. Tawfic, A.M. El-Tawdy, M.H.M. El-Komy, M. El Menyawi and A.A. Heikal, 2014. Expression of TNF-𝛼, april and BCMA in behcet’s disease. J. Immunol. Res., Vol. 2014. 10.1155/2014/380405.
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  99. Shaker, O.G., M.F. Ismail, E. Ashour, H.M. Yousif, M. Afify and W. Gouda, 2014. ACE gene polymorphism and serum ACE level with progression of nephropathy in type 2 diabetic patients. J. Adv. Chem., 9: 2023-2032.
  100. Shaker, O.G. and M.F. Ismail, 2014. Association of genetic variants of MTHFR, ENPP1, and ADIPOQ with myocardial infarction in Egyptian patients. Cell Biochem. Biophys., 69: 265-274.
    CrossRef  |  Direct Link  |  
  101. Saad, Y., O. Shaker, Y. Nassar, L. Ahmad, M. Said and G. Esmat, 2014. A polymorphism in the microsomal triglyceride transfer protein can predict the response to antiviral therapy in Egyptian patients with chronic hepatitis C virus genotype 4 infection. Gut Liver, 8: 655-661.
    CrossRef  |  Direct Link  |  
  102. Nacif, M., R. Talaat and O. Shaker, 2014. Transforming growth factor- β 1 (TGF- β 1) gene expression and protein level in blood as prognostic and diagnostic tools in cancer patients. Eur. J. Biotechnol. Biosci., 2: 01-07.
  103. Nacif, M. and O. Shaker, 2014. Targeting transforming growth factor-β (TGF-β) in cancer and non-neoplastic diseases. J. Cancer Ther., 5: 735-747.
    CrossRef  |  Direct Link  |  
  104. Motawi, T.M., O.G. Shaker, M.M. El-Sawalhi and Z.M. Abdel-Nasser, 2014. Visfatin -948 G/T and Resistin -420 C/G polymorphisms in Egyptian type 2 diabetic patients with and without cardiovascular diseases. Genome., 57: 259-266.
    CrossRef  |  Direct Link  |  
  105. Mohamed, A.A., W.G. Shousha, O. Shaker, M.M. El-Sayed, E.M.A. Ibrahim, S. Mohmoud and A. khairalla, 2014. Role of serum adiponectin, IL-6 and Hs CRP in nonalcoholic fatty liver Egyptian patients. Int. J. Biochem. Res. Rev., 4: 493-504.
  106. Menyawi, M., M.W. Fawzy, Y.Y. Ojra, O.G. Shaker and A. Edrees, 2014. Role of serum TNFα level in atherosclerosis in Egyptian systemic lupus erythematosus patients. J. Diagn. Med. Sonography, 30: 290-295.
    CrossRef  |  Direct Link  |  
  107. Mashaly, H.M., K.S. Sayed, F.N. Mohammad, O.G. Shaker and M.G. Saeed, 2014. Estimation of serum zinc and copper in Egyptian patients with pemphigus vulgaris. J. Egypt. Women's Dermatol. Soc., 11: 32-35.
    CrossRef  |  Direct Link  |  
  108. Hussein1, J., D.A. El-Matty, O. Shaker, Z. El-Khayat, W. Rasheed and J. Raafat, 2014. Prevention of protein kinase C isozyme elevation by flaxseed oil in experimental Diabetes. World J. Pharm. Pharm. Sci., 3: 245-256.
  109. Hussein, J., Z. El-Khayat, O. Shaker, D.A. El-Matty, W. Rasheed and J. Raafat, 2014. Regulation of glucose transportations in cell membrane during diabetes: impact of flaxseed oil supplementation. World J. Pharm. Pharm. Sci., 3: 113-125.
  110. Hassan, E.M., O.G. Shaker, M.S.A. Bary, H. Ghoneim, M.A. Mohey, R.N. Marzaban and L.A. Hafez, 2014. Biliary and serum insulin-like growth Factor-I: Are they reliable diagnostic markers in cholangiocarcinoma? World J. Med. Sci., 11: 155-160.
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  111. Esmat, S., D. Elgendy, M. Ali, S. Esmat, E.A. El-Nabarawy, S.B. Mahmoud and O. Shaker, 2014. Prevalence of photosensitivity in chronic hepatitis C virus patients and its relation to serum and urinary porphyrins. Liver Int., 34: 1033-1039.
    CrossRef  |  Direct Link  |  
  112. Eskander1, F., A.A. Abd-Rabou, S.M.M. Yahya, A.E. Sherbini, M.S. Mohamed and O.G. Shaker, 2014. The impact of pegylated-interferon-a plus ribavirin on prolactinemia and testosteronemia among hepatitis c-genotype-4a patients. Open J. Biochem., 1: 25-36.
    CrossRef  |  
  113. Eskander, E.F., A.A. Abd-Rabou, M.S. Mohamed, S.M. Yahya, A. El Sherbini and O.G. Shaker, 2014. The potential impact of P53 and APO-1 genetic polymorphisms on hepatitis C genotype 4a susceptibility. Gene, 550: 40-45.
    CrossRef  |  Direct Link  |  
  114. El-Komy, M.H., S.O. Tawfik and O.G. Shaker, 2014. Expression of the B-cell maturation antigen and a proliferation-inducing ligand in psoriatic plaques. J. Egypt. Women’s Dermatol. Soc., 11: 50-54.
    CrossRef  |  Direct Link  |  
  115. El-Komy, M.H., N. Samir and O.G. Shaker, 2014. Estimation of vitamin D levels in patients with pemphigus vulgaris. J. Eur. Acad. Dermatol. Venereol., 28: 859-863.
    CrossRef  |  Direct Link  |  
  116. El-Hadidi, H., N. Samir, O.G. Shaker and S. Otb, 2014. Estimation of tissue and serum lipocalin-2 in psoriasis vulgaris and its relation to metabolic syndrome. Arch. Dermatol. Res., 306: 239-245.
    CrossRef  |  Direct Link  |  
  117. El-Garem, H., A. Ammer, H. Shehab, O. Shaker, M. Anwer, W. El-Akel and H. Omar, 2014. Circulating microRNA, miR-122 and miR-221 signature in Egyptian patients with chronic hepatitis C related hepatocellular carcinoma. World J. Hepatol., 6: 818-824.
    CrossRef  |  Direct Link  |  
  118. El Menyawi, M., M. Fawzy, Z. Al-Nahas, A. Edris, H. Hussein, O. Shaker and H. Elwan, 2014. Serum tumor necrosis factor alpha (TNF-α) level in patients with Behçet’s disease: Relation to clinical manifestations and disease activity. Egypt. Rheumatol., 36: 139-143.
    CrossRef  |  Direct Link  |  
  119. Shaker, O.G., Y.H. Nassar, Z.A. Nour and M. El Raziky, 2013. Single-nucleotide polymorphisms of IL-10 and IL-28B as predictors of the response of IFN therapy in HCV genotype 4-infected children. J. Pediatr. Gastroenterol. Nutr., 57: 155-160.
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  120. Shaker, O.G., O.A. Hammam and M.M. El-Lithy, 2013. Is there a correlation between HPV and urinary bladder carcinoma? Biomed. Pharmacother., 67: 183-191.
    CrossRef  |  Direct Link  |  
  121. Shaker, O.G., N.A. Sadik and N.A. El-Hamid, 2013. Impact of single nucleotide polymorphism in tumor necrosis factor-α gene 308G/A in Egyptian asthmatic children and wheezing infants. Hum. Immunol., 74: 796-802.
    CrossRef  |  Direct Link  |  
  122. Shaker, O.G., M. Khairallah, H.M. Rasheed, M.R. Abdel-Halim and O.M. Abuzeid et al., 2013. Antiangiogenic effect of methotrexate and PUVA on psoriasis. Cell Biochem. Biophys., 67: 735-742.
    CrossRef  |  Direct Link  |  
  123. Shaker, O.G. and N.A. Sadik, 2013. Vaspin gene in rat adipose tissue: Relation to obesity-induced insulin resistance. Mol. Cell Biochem., 373: 229-239.
    CrossRef  |  Direct Link  |  
  124. Shaker, O.G. and N.A. Sadik, 2013. Pathogenesis of preeclampsia: implications of apoptotic markers and oxidative stress. Hum. Exp. Toxicol., 32: 1170-1178.
    CrossRef  |  Direct Link  |  
  125. Shaker, O.G. and D.A. Sourour, 2013. Protective effects of pomegranate seed extract on streptozotocin-induced β-cell damage in rats: Inhibition of pancreatic nuclear factor kappa beta, transforming growth factor beta and matrix metalloproteinase-2 genes expression. Int. J. Adv. Res., 1: 88-102.
    Direct Link  |  
  126. Shaker, O., O. Hammam, M. Wishahi and M. Roshdi, 2013. TGF-В1 pathway as biological marker of bladder carcinoma schistosomal and non-schistosomal. Urol. Oncol., 31: 372-378.
    CrossRef  |  Direct Link  |  
  127. Shaker, O., N.A. Ghallab, E. Hamdy and S. Sayed, 2013. Inducible nitric oxide synthase (iNOS) in gingival tissues of chronic periodontitis with and without diabetes: Immunohistochemistry and RT-PCR study. Arch. Oral Biol., 58: 1397-1406.
    CrossRef  |  Direct Link  |  
  128. Shaker, O., H. Bassiony, M. El Raziky, S.S. El-Kamary, G. Esmat, A.M. El-Ghor and M.M. Mohamed, 2013. Human leukocyte antigen class II alleles (DQB1 and DRB1) as predictors for response to interferon therapy in HCV genotype 4. Mediators Inflamm., Vol. 2013 10.1155/2013/392746.
    CrossRef  |  Direct Link  |  
  129. Shaker, O., A.A. Mohamed, H. El Sayed, A. Ebrahim, E. Mohamed and M.A. Atallah, 2013. PIVKA-II as early diagnostic marker for hepatocellular carcinoma: An Egyptian study. Int. J. Adv. Res., 1: 135-141.
  130. Shaker, O., A. El-Shehaby, S. Fayez, A. Zahra, S. Marzouk and M. El Raziky, 2013. Osteopontin gene polymorphisms as predictors for the efficacy of interferon therapy in chronic hepatitis C Egyptian patients with genotype 4. Cell Biochem. Funct., 31: 620-625.
    CrossRef  |  Direct Link  |  
  131. Shaker, O. and N. Sadik, 2013. Transforming growth factor-beta 1 and monocyte chemoattractant protein-1 as prognostic markers of diabetic nephropathy. Hum. Exp. Toxicol., 32: 1089-1096.
    CrossRef  |  Direct Link  |  
  132. Seif, E.N.H., O.G. Shaker, M.M. Fawzi and G. El-Hanafi, 2013. Basic fibroblast growth factor and tumor necrosis factor alpha in vitiligo and other hypopigmented disorders: suggestive possible therapeutic targets. J. Eur. Acad Dermatol. Venereol., 27: 103-108.
    CrossRef  |  Direct Link  |  
  133. Sadik, N.A. and O.G. Shaker, 2013. Inhibitory effect of a standardized pomegranate fruit extract on wnt signalling in 1, 2-dimethylhydrazine induced rat colon carcinogenesis. Dig. Dis. Sci., 58: 2507-2517.
    CrossRef  |  Direct Link  |  
  134. Motawi, T.K., O.G. Shaker, M.F. Ismail and N.H. Sayed, 2013. Genetic variants associated with the progression of hepatocellular carcinoma in hepatitis C Egyptian patients. Gene, 527: 516-520.
    CrossRef  |  Direct Link  |  
  135. Marzouk, H.A., N.A. Zayed, M. Al-Ansary, M.S. Abdelbary, S.S. Hunter, W. Safwat, M. Abdel-Moneim and O. Shaker, 2013. Hepcidin levels in Egyptian patients with chronic hepatitis c and the effect of anti-viral therapy. World Appl. Sci. J., 22: 1140-1145.
    CrossRef  |  Direct Link  |  
  136. Ismail, M.M., H. El-Ghamry, O.G. Shaker, M.M. Fawzi and S.F. Ibrahim, 2013. Some biomarkers in carbon monoxide-induced cardiotoxicity. J. Environ. Anal. Toxicol., Vol. 3. 10.4172/2161-0525.1000176.
    CrossRef  |  Direct Link  |  
  137. Fouad, R., O. Shaker, H.A. Hafez, R. Salama and M. El Raziky et al., 2013. HIV prevalence among HCV Egyptian infected patients and its impact on the result of HCV treatment. Adv. Infect. Dis., 3: 71-77.
    CrossRef  |  Direct Link  |  
  138. Fat’heya, M.Z., S.A. Al-Attas, O.G. Shaker and M.H.A. Hassan, 2013. An insight into the pathogenesis of oral lichen planus: A genomic and proteomic case-control study. Aust. J. Basic Appl. Sci., 7: 480-487.
    Direct Link  |  
  139. El-Tahlawi, S.R., G.M. El-Hanafy, A.E.A.A. El-Rifaie and O.G. Shaker, 2013. Assessment of the level of tumor necrosis factor-α in localized alopecia areata. J. Egypt. Women’s Dermatol. Soc., 10: 81-84.
    CrossRef  |  Direct Link  |  
  140. El-Khayat, Z., D.A. El-Matty, W. Rasheed, J. Hussein, O. Shaker and J. Raafat, 2013. Role of cell memmbrane fatty acids in insulin sensitivity in diabetic rats treated with flaxseed oil. Int. J. Pharm. Pharm. Sci., 5: 146-151.
    Direct Link  |  
  141. El-Kamary, S.S., M.M. Mohamed, M. El-Raziky, M.D. Shardell, O.G. Shaker, W.A. Elakel and G. Esmat, 2013. Liver fibrosis staging through a stepwise analysis of non-invasive markers (FibroSteps) in patients with chronic hepatitis C infection. Liver Int., 33: 982-990.
    CrossRef  |  Direct Link  |  
  142. El Raziky, M., D. Attia, W. El akel, O. Shaker, H. Khatab, S. Abdo, A. Elsharkawy and G. Esmat, 2013. Hepatic fibrosis and serum alpha-fetoprotein (AFP) as predictors of response to HCV treatment and factors associated with serum AFP normalisation after treatment. Arab J. Gastroentrol., 14: 94-98.
    CrossRef  |  Direct Link  |  
  143. Bosseila, M., S.O. Tawfic, M.A. Ezzat and O.G. Shaker, 2013. Tissue liver X-receptor-α (LXRα) level in acne vulgaris. J. Egypt. Women’s Dermatol. Soc., 10: 101-105.
    CrossRef  |  Direct Link  |  
  144. Al Azrak, M., T. Ismail and O. Shaker, 2013. Evaluation of the potentials of autologous blood injection for healing in diabetic foot ulcers; three study cases. J. Am. Coll. Clin. Wound Spec., 4: 45-50.
    CrossRef  |  Direct Link  |  
  145. Abou-Khadra, M.K., O.R. Amin, O.G. Shaker and T.M. Rabah, 2013. Parent-reported sleep problems, symptom ratings, and serum ferritin levels in children with attention-deficit/hyperactivity disorder: a case control study. BMC Pediatr., 13: 217-217.
    CrossRef  |  Direct Link  |  
  146. Abou-Khadra, M.K., N.A. Kishk, O.G. Shaker and A. Hassan, 2013. Urinary 6-sulphatoxymelatonin levels and sleep disorders in children with migraine. J. Child Neurol., 29: 947-951.
    CrossRef  |  Direct Link  |  
  147. Abd-El-Fattah, A.A., N.A. Sadik, O.G. Shaker and M.L. Aboulftouh, 2013. Differential microRNAs expression in serum of patients with lung cancer, pulmonary tuberculosis and pneumonia. Cell Biochem. Biophys., 67: 875-884.
    CrossRef  |  Direct Link  |  
  148. Youssef, R., R.A. Hegazy, M.M. Fawzy, D.M. Abdel Halim, N. Nabil, S.S. Sayed and O.G. Shaker, 2012. Peroxisome proliferator-activated receptor gamma, a possible culprit in mycosis fungoides: an immunohistochemical study. J. Eur. Acad. Dermatol. 26: 1522-1532.
    Direct Link  |  
  149. Shaker, O.G., N.A. Sadik and A. El- 2012. Single-nucleotide polymorphism in the promoter region of the osteopontin gene at nucleotide -443 as a marker predicting the efficacy of pegylated interferon/ribavirin-therapy in Egyptians patients with chronic hepatitis C. Hum. Immunol., 73: 1039-1045.
    Direct Link  |  
  150. Shaker, O.G. and N.A. Sadik, 2012. Polymorphisms in interleukin-10 and interleukin-28B genes in Egyptian patients with chronic hepatitis C virus genotype 4 and their effect on the response to pegylated interferon/ribavirin-therapy. J. Gastroenterol. Hepatol., 27: 1842-1849.
    Direct Link  |  
  151. Shaker, O. and N. Ghallab, 2012. IL-17 and IL-11 GCF levels in aggressive and chronic periodontitis patients: Relation to PCR bacterial detection. Mediators Inflamm., Vol. 20122012. IL-17 and IL-11 GCF levels in aggressive and chronic periodontitis patients: Relation to PCR bacterial detection. Mediators Inflamm., Vol. 2012 10.1155/2012/174764.
    CrossRef  |  Direct Link  |  
  152. Shaker, O. and M. Abdel-Halim, 2012. Connexin 26 in psoriatic skin before and after two conventional therapeutic modalities: Methotrexate and PUVA. Eur. J. Dermatol., 22: 218-224.
    CrossRef  |  Direct Link  |  
  153. Shaker, O. and A. Saad, 2012. Possible role of interleukin-17 in the pathogenesis of lichen planus. Br. Assoc. Dermatol., 166: 1357-1380.
    CrossRef  |  Direct Link  |  
  154. Sadik, N.A. and O. Shaker, 2012. Dietary folate suppresses DMH-induced colon carcinogenesis in a rat model and affects DMH-induced expression of four DNA repair enzymes. Nutr. Cancer, 64: 1196-1203.
    Direct Link  |  
  155. Ratib, A., M.H. Elkomy, S.O. Tawfic, M.M. Soliman and O.G. Shaker, 2012. TLR4 and its adaptor protein MyD88 in inflammatory and noninflammatory lesions of acne vulgaris. J. Egypt. Women’s Dermatol. Soc., 9: 102-107.
    CrossRef  |  Direct Link  |  
  156. Motawi, T., O. Shaker, N. Taha and M.A. Raheem, 2012. Genetic variations in E-selectin and ICAM-1: Relation to atherosclerosis. Med. Sci. Monitor: Int. Med. J. Exp. Clin. Res., 18: CR381-CR389.
    CrossRef  |  PubMed  |  Direct Link  |  
  157. Mostafa, T., L.H. El-Shahid, A.A. El Azeem, O. Shaker, H. Gomaa and H.M. Abd El Hamid, 2012. Androgen receptor-CAG repeats in infertile Egyptian males. Andrologia, 44: 147-151.
    CrossRef  |  Direct Link  |  
  158. Mahdy, K., O. Shaker, H. Wafay, Y. Nassar, H. Hassan, A. Hussein, 2012. Effect of some medicinal plant extracts on the oxidative stress status in Alzheimer’s disease induced in rats. Eur. Rev. Med. Pharmacol. Sci., 16: 31-42.
  159. Khattab, M.A., M. Eslam, M. Shatat, H. Abd-Aalhalim, Y.I. Mousa, F. Samir and Y. Shaker, 2012. Changes in adipocytokines and insulin sensitivity during and after antiviral therapy for hepatitis C genotype 4. J. Gastrointestinal Liver Dis., 21: 59-65.
  160. Ismail, N.A., S.H. Okasha, A. Dhawan, A.M.O. Abdel Rahman, N.A. Hamid and O. Shaker, 2012. Glutathione peroxidase, superoxide dismutase and catalase activities in children with chronic hepatitis. Adv. Biosci. Biotechnol., 3: 972-977.
    Direct Link  |  
  161. Ibrahim, R.O. and O. Shaker, 2012. The effectiveness of adjunctive systemic antibiotics to non surgical therapy in chronic periodontitis patients. J. Am. Sci., 8: 374-383.
    Direct Link  |  
  162. Hegazy, R.A., R.M.A. Hay, O. Shaker, S.S. Sayed and D.A.A. Halim, 2012. Psoriasis and metabolic syndrome: Is peroxisome proliferator-activated receptor-γ part of the missing link? Eur. J. Dermatol., 22: 622-628.
    Direct Link  |  
  163. Hashem, A.M., M.E.M. Rasmy, K.M. Wahba and O.G. Shaker, 2012. Single stage and multistage classification models for the prediction of liver fibrosis degree in patients with chronic hepatitis C infection. Comput. Methods Programs Biomed., 105: 194-209.
    CrossRef  |  Direct Link  |  
  164. Hafed, L., H. Farag, O. Shaker and D. El-Rouby, 2012. Is human papilloma virus associated with salivary gland neoplasms? An in situ-hybridization study. Arch. Oral Biol., 57: 1194-1199.
    CrossRef  |  Direct Link  |  
  165. Ghalwash, D.M., K.E. Gaaly, F.M. Zahran, O. Shaker and H.A. El-Fol, 2012. The diagnostic and prognostic value of salivary sCD44 level determination in oral malignant and potentially premalignant lesions. Adv. Environ. Biol., 6: 302-310.
  166. Eskander, E.F., A.A. Abd-Rabou, S.M.M. Yahya, O.G. Shaker and M.S. Mohamed, 2012. Does interferon and ribavirin combination therapy ameliorate growth hormone deficiency in HCV genotype-4 infected patients? Clin. Biochem., 45: 3-6.
    CrossRef  |  Direct Link  |  
  167. Eskander, E.F., A.A. Abd-Rabou, M.S. Mohamed, S.M. Yahya and O.G. Shaker, 2012. Does HCV patients who have BCL2 43Ala genotype and normal GH1 levels can achieve response to IFN based therapy? Indian J. Clin. Biochem., 27: 344-350.
    CrossRef  |  Direct Link  |  
  168. Elmongy, N.N. and O. Shaker, 2012. Expression of peroxisome proliferator activator receptor β/δ (PPARβ/δ) in acne vulgaris. Eur. J. Dermatol., 22: 42-45.
    CrossRef  |  Direct Link  |  
  169. Eldin, A.B., S. Sayed, G. Hegazy and O. Shaker, 2012. B-cell activating factor (BAFF) in systemic lupus erythematosus, rheumatoid arthritis and behcet’s disease. Turk. J. Rheumatol., 27: 185-194.
    Direct Link  |  
  170. El Safoury, O.S., O.G. Shaker and M.M. Fawzy, 2012. Skin tags and acanthosis nigricans in patients with hepatitis C infection in relation to insulin resistance and insulin like growth factor-1 levels. Indian J. Dermatol., 57: 102-106.
    CrossRef  |  Direct Link  |  
  171. El Abiad, N.M., H. Waheed, W.M. Morcos, S.M. Salem, H. Ataa and O.G. Shaker, 2012. Association between CC16 polymorphism and bronchial asthma. Life Sci. J., 9: 265-270.
    Direct Link  |  
  172. Al-Azrak, M. and O. Shaker, 2012. Saving big toe of diabetic foot by using autologous blood injection: a case report. J. Wound Technol., 17: 25-28.
  173. Abbas, E., O. Shaker, G.A. El Aziz, H. Ramadan and G. Esmat, 2012. Epidermal growth factor gene polymorphism 61A/G in patients with chronic liver disease for early detection of hepatocellular carcinoma: A pilot study. Eur. J. Gastroenterol. Hepatol., 24: 458-463.
    CrossRef  |  Direct Link  |  
  174. Shaker, O.G., O.A. Hammam, T.R. El Leithy, H. El Ganzoury, M.M. Wishahi and D.P. Mikhailidis, 2011. Molecular markers and bladder carcinoma: Schistosomal and non-schistosomal. Clin. Biochem., 44: 237-244.
    CrossRef  |  Direct Link  |  
  175. Shaker, O.G., E.F. Eskander, S.M. Yahya, M.S. Mohamed and A.A. Abd-Rabou, 2011. Genetic variation in BCL-2 and response to interferon in hepatitis C virus type 4 patients. Clin. Chim. Acta, 412: 593-598.
    CrossRef  |  Direct Link  |  
  176. Shaker, O.G., A.H. Fayez and I.A. Osman, 2011. Is there a relationship between endothelial nitric oxide synthase and erectile dysfunction in Egyptian males? Res. Rev. Biosci., 5: 173-175.
  177. Shaker, O.G. and H. Shehata, 2011. Early prediction of preeclampsia in high-risk women. J. Women's Health, 20: 539-544.
    CrossRef  |  Direct Link  |  
  178. Shaker, O.G. and D.A. Sourour, 2011. Effect of leukotriene receptor antagonists on lung fibrosis in rats. J. App. Toxicol., 31: 678-684.
    CrossRef  |  Direct Link  |  
  179. Shaker, O., A. El-Shehaby, A. Zakaria, N. Mostafa, S. Talaat, N. Katsiki and D.P. Mikhailidis, 2011. Plasma visfatin and retinol binding protein-4 levels in patients with type 2 diabetes mellitus and their relationship to adiposity and fatty liver. Clin. Biochem., 44: 1457-1463.
    CrossRef  |  Direct Link  |  
  180. Shaker, O., A. Ahmed, I. Abdel Satar, H. El Ahl, W. Shousha and W. Doss, 2011. Occult hepatitis B in Egyptian thalassemic children. J. Infect. Dev. Count., 6: 340-346.
    CrossRef  |  Direct Link  |  
  181. Samar, M.F., T.A. Gheita, E. El-Nabarawyb, H.H. El-Demellawy and O.G. Shaker, 2011. Serum BAFF level and its correlations with various disease parameters in patients with systemic sclerosis and systemic lupus erythematosus. Egypt. Rheumatol., 33: 45-51.
    CrossRef  |  Direct Link  |  
  182. Sadik, N.A.H., M.M. El-Seweıdy and O.G. Shaker, 2011. The antiapoptotic effects of sulphurous mineral water and sodium hydrosulphide on diabetic rat testes. Cell Physiol. Biochem., 28: 887-898.
    CrossRef  |  Direct Link  |  
  183. Saad, Y., S. Zakaria, I. Ramzy, M. El Raziky, O. Shaker, M. Said and G. Esmat, 2011. Prevalence of occult hepatitis C in Egyptian patients with non alcoholic fatty liver disease. Open J. Int. Med. 1: 33-37.
    Direct Link  |  
  184. Ramzy, I.I., D.A. Omran, O. Hamad, O. Shaker and A. Abboud, 2011. Evaluation of serum LINE-1 hypomethylation as a prognostic marker for hepatocellular carcinoma. Arab J. Gastroenterol., 12: 139-142.
    CrossRef  |  Direct Link  |  
  185. Motawi, T., O. Shaker, M. Taha, H. Sedrak and M. Nabil, 2011. Endothelial nitric oxide synthase and angiotensinogen gene polymorphism in coronary artery diseases in Egypt. Angiology, 62: 191-197.
    CrossRef  |  Direct Link  |  
  186. Mashaly, H.M., H. Helal and O.G. Shaker, 2011. Evaluation of B-cell activating factor in corticosteroid-treated systemic lupus erythematosus patients. J. Egypt. Women’s Dermatol. Soc., 8: 84-89.
    CrossRef  |  Direct Link  |  
  187. Hunter, N., O. Shaker and N. Marei, 2011. Diphencyprone and topical tacrolimus as two topical immunotherapeutic modalities. Are they effective in the treatment of alopecia areata among Egyptian patients? A study using CD4, CD8 and MHC II as markers. J. Dermatol. Treat., 22: 2-10.
    CrossRef  |  Direct Link  |  
  188. El‐Komy, M., I. Amin, A. Zidan, D. Kadry, O.A. Zeid and O. Shaker, 2011. Insulin‐like growth factor‐1 in psoriatic plaques treated with PUVA and methotrexate. J. Eur. Acad. Dermatol. Venereol., 25: 1288-1294.
    CrossRef  |  Direct Link  |  
  189. Elbadri, A., S. Esmat, N. Abosaif, A. Morsi and O. Shaker, 2011. Study of serum ghrelin changes and its correlation with malnutrition in liver cirrhosis in Egypt. Clin. Res. Hepatol. Gastroenterol., 35: 638-643.
    CrossRef  |  Direct Link  |  
  190. Elassiuty, Y.E., J. Klarquist, J. Speiser, R.M. Yousef, A.A. El Refaee, N.S. Hunter and I. Caroline Le Poole, 2011. Heme oxygenase‐1 expression protects melanocytes from stress‐induced cell death: Implications for vitiligo. Exp. Dermatol., 20: 496-501.
    CrossRef  |  Direct Link  |  
  191. El-Seweidy, M.M., N.A. Sadik and O.G. Shaker, 2011. Role of sulfurous mineral water and sodium hydrosulfide as potent inhibitors of fibrosis in the heart of diabetic rats. Arch. Biochem. Biophys., 506: 48-57.
    CrossRef  |  Direct Link  |  
  192. El-Abiad, N., M.H. Wagdi, A. Amira, W. Hisham and S. Olfat, 2011. Chlamydia pneumonia infection and possible relationship to childhood bronchial asthma. J. Am. Sci., 7: 593-599.
    Direct Link  |  
  193. El Eishi, N., R. Hegazy, O.A. Zeid and O. Shaker, 2011. Peroxisome Proliferator Receptor (PPAR) β/δ in psoriatic patients before and after two conventional therapeutic modalities: Methotrexate and PUVA. Eur. J. Dermatol., 21: 691-695.
    CrossRef  |  Direct Link  |  
  194. Bassiouny, D.A. and O. Shaker, 2011. Role of interleukin‐17 in the pathogenesis of vitiligo. Clin. Exp. Dermatol., 36: 292-297.
    CrossRef  |  Direct Link  |  
  195. Abou El‐Ela, M., A.E.A. El‐Rifae, M. Fawzi, R. Abdel Hay, Y. Gohary and O. Shaker, 2011. Thymus and activation‐regulated chemokine in different stages of mycosis fungoides: Tissue and serum levels. Aust. J. Dermatol., 52: 167-171.
    CrossRef  |  Direct Link  |  
  196. Shaker, O.G., A. El Shehaby and M. Nabih, 2010. Possible role of osteoprotegerin and tumor necrosis factor-related apoptosis-inducing ligand as markers of plaque instability in coronary artery disease. Angiology, 61: 756-762.
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  197. Shaker, O., A. Zahra, A. Sayed, A. Refaat, Z. El-Khaiat, G. Hegazy and M. Ay-El Deen, 2010. Role of ICAM-1 and E-selectin gene polymorphisms in pathogenesis of PAOD in Egyptian patients. Vasc. Health Risk Manag., 6: 9-15.
    Direct Link  |  
  198. Shaker, O., A. El Shehaby and M. El Khatib, 2010. Early diagnostic markers for contrast nephropathy in patients undergoing coronary angiography. Angiology, 61: 731-736.
    CrossRef  |  
  199. Shaker, O., A. Ahmed, W. Doss and M. Abdel‐Hamid, 2010. MxA expression as marker for assessing the therapeutic response in HCV genotype 4 Egyptian patients. J. Viral Hepat., 17: 794-799.
    CrossRef  |  Direct Link  |  
  200. Shaker, O. and D.A. Sourour, 2010. How to protect doxorubicin-induced cardiomyopathy in male albino rats?. J. Cardiovasc. Pharmacol., 55: 262-268.
    CrossRef  |  Direct Link  |  
  201. Ismail, N.A., S.H. Okasha, A. Dhawan, A.O. Abdelrahman, O.G. Shaker and N.A. Sadik, 2010. Antioxidant enzyme activities in hepatic tissue from children with chronic cholestatic liver disease. Saudi J. Gastroenterol., 16: 90-94.
    PubMed  |  Direct Link  |  
  202. Ghallab, N.A., N. El-Wakeel and O.G. Shaker, 2010. Levels of salivary IFN-gamma, TNF-alfa and TNF receptor-2 as prognostic markers in (erosive) oral lichen planus. Med. Inflamm., Vol. 2010. 10.1155/2010/847632.
    CrossRef  |  
  203. Ghallab N. and O. Shaker, 2010. Salivary soluble CD44 levels in smoker and non-smoker subjects with chronic periodontitis: A pilot study. J. Periodontol., 81: 710-717.
  204. El-Darouti, M.A., H.M. Mashaly, E. El-Nabarawy, A.M. Eissa, M.R. Abdel-Halim, M.M. Fawzi and M. Fawzi, 2010. Leukocytoclastic vasculitis and necrolytic acral erythema in patients with hepatitis C infection: Do viral load and viral genotype play a role?. J. Am. Acad. Dermatol., 63: 259-265.
    CrossRef  |  Direct Link  |  
  205. Assimon, M., S. Mousa, O. Shaker and A.B. Pai, 2010. The effect of sevelamer hydrochloride and calcium-based phosphate binders on mortality in hemodialysis patients: A need for more research. Consult. Pharm., 25: 41-54.
    CrossRef  |  Direct Link  |  
  206. Zaher, H., O.G. Shaker, M.H.M. El-Komy, A. El-Tawdi, M. Fawzi and D. Kadry, 2009. Serum and tissue expression of transforming growth factor beta 1 in psoriasis. J. Eur. Acad. Dermatol. Venereol., 23: 406-409.
    CrossRef  |  Direct Link  |  
  207. Shaker, O.G., O. Hammam, A. Salehd, T. El-Leithy and M. Wishahi, 2009. Possible role of telomerase and sFas in pathogenesis of various bladder lesions associated with schistosomiasis. Clin. Biochem., 42: 864-872.
    CrossRef  |  Direct Link  |  
  208. Shaker, O.G., N. Hantar, S. El‐Tahlawi, A. El‐Tawdi, H. El‐Hadidi, S. Hantar and R. William, 2009. Detection of myxovirus resistance protein A in lichen planus lesions and its relationship to hepatitis C virus. Br. J. Dermatol., 160: 980-983.
    CrossRef  |  Direct Link  |  
  209. Shaker, O.G., M. El-Komy, S.O. Tawfic, N. Zeidan and R.H. Tomairek, 2009. Possible role of nerve growth factor and interleukin-18 in pathogenesis of eczematous lesions of atopic dermatitis. J. Dermatol. Sci., 53: 153-154.
    CrossRef  |  Direct Link  |  
  210. Shaker, O.G., H.H. Eldemellawy and H.H. Kassem, 2009. Angiotensinogen gene (M235T) polymorphism and coronary artery disease in the Egyptian population: A genetic association study. Heart Mirror J., 3: 86-91.
  211. Shaker, O.G., D.A. Sourour and M. Taha, 2009. Effects of statins on insulin-like growth factor-1 gene expression in fructose induced metabolic syndrome in rats. Open Endocrinol. J., 3: 28-33.
  212. Rebbaa, A., F. Chu, T. Sudha, C. Gallati, U. Dier, E. Dyskin and S.A. Mousa, 2009. The anti-angiogenic activity of NSITC, a specific cathepsin L inhibitor. Anticancer Res., 29: 4473-4481.
    Direct Link  |  
  213. Osman, I.A. and O.G. Shaker, 2009. Sildenafil non-responders: The relation of polymorphism ACE gene I/D to response to sildenafil. Med. J. Cairo Univ., 77: 77-85.
  214. Martin, J.W., S.S. Mousa, O. Shaker and S.A. Mousa, 2009. The multiple faces of nicotine and its implications in tissue and wound repair. Exp. Dermatol., 18: 497-505.
    CrossRef  |  Direct Link  |  
  215. Kamel, Y.H., H.M. Bazaraa, A.E. Elwan, N.A. Fahmy and O. Shaker, 2009. Apoptotic markers in childhood nephrotic syndrome. J. Biol. Sci., 9: 509-513.
    CrossRef  |  Direct Link  |  
  216. Ismail, N.A., S.H. Okasha, A. Dhawan, A.M.O.A. Rahman, O.G. Shaker and N.A.H. Sadik, 2009. Glutathione peroxidase, superoxide dismutase and catalase activities in hepatic tissue from children with glycogen storage disease. Arch. Med. Sci., 5: 86-90.
    Direct Link  |  
  217. Elkoofy, N., M.E. Fahmy, H. Helmy, O. Shaker and N. Mohsen, 2009. Serum and hepatic copper concentrations in Egyptian infants with cholestasis. Med. J. Cairo Univ., 77: 111-115.
  218. Atta, H.M., A. Al‐Hendy, S.A. Salama, O.G. Shaker and O.A. Hammam, 2009. Low‐dose simultaneous delivery of adenovirus encoding hepatocyte growth factor and vascular endothelial growth factor in dogs enhances liver proliferation without systemic growth factor elevation. Liver Int., 29: 1022-1030.
    CrossRef  |  Direct Link  |  
  219. Topiwala, M.A., O. Shaker and S.A. Mousa, 2008. RP: Understanding the Problems and the Potential. Rev. Ophthalmol. Online., 15: 12-15.
  220. Shaker, O.G. and S.M. El-Tahlawi, 2008. Is there a relationship between homocysteine and vitiligo? A pilot study. Br. J. Dermatol., 159: 720-724.
    CrossRef  |  Direct Link  |  
  221. Shaker, O., A. Hashem, L. Mansour and O. Taha, 2008. Possible role of C-erb B2 and transforming growth factor B1 in malignant transformation of hepatocytes. Biochem. Clin., 32: 84-88.
  222. Mansy, W.H., D.A. Sourour, O.G. Shaker and M.M. Mahfouz, 2008. Fluvastatin increases insulin-like growth factor-1 gene expression in rat model of metabolic syndrome. Saudi Pharm. J., 16: 146-154.
    Direct Link  |  
  223. Fawzi, M.M., S.O. Tawfik, A.M. Eissa, M.H. El-Komy, M.R. Abdel-Halim and O.G. Shaker, 2008. Expression of insulin-like growth factor-I in lesional and non-lesional skin of patients with morphoea. Br. J. Dermatol., 159: 86-90.
    CrossRef  |  Direct Link  |  
  224. El-Beshlawy, A., C. Manz, M. Naja, M. Eltagui and C. Tarabishi et al., 2008. Iron chelation in thalassemia: Combined or monotherapy? The Egyptian experience. Ann. Hematol., 87: 545-550.
    CrossRef  |  Direct Link  |  
  225. El Ashiry, S.G., S.G. El Ashiry and O. Shaker, 2008. Evaluation of salivary interleukin-6 as a sensitive marker in acute exacerbation and remission of oral lichen planus. Egypt. Dent. J., 54: 2037-2048.
  226. El Ashiry, S.G., S.G. El Ashiry and O. Shaker, 2008. Estimation of salivary interleukin-6 level during the ulcerative and healing stages of minor recurrent aphthous ulcer in monitoring the disease activity. Egypt. Dent. J., 54: 2509-2520.
  227. Youssry, I., N.A. Mohsen, O.G. Shaker, A. El-Hennawy, R. Fawzy, N.M. Abu-Zeid and A. El-Beshlawy, 2007. Skin iron concentration: A simple, highly sensitive method for iron stores evaluation in thalassemia patients. Hemoglobin, 31: 357-365.
    CrossRef  |  Direct Link  |  
  228. Sohir, Z., F. Rabab, S. Olfat, S. Zaki and H. Ahmed et al., 2007. Changing pattern of acute viral hepatitis at a majour urban refereal center in Egypt. Clin. Infec. Dis., 44: e30-e36.
    CrossRef  |  Direct Link  |  
  229. Shaker, O., M.A.A. El-Deen, H.E. Hadidi, B.D. Grace, H.E. Sherif and A.A. Halim, 2007. The role of heat shock protein 60, vascular endothelial growth factor and antiphospholipid antibodies in Behçet disease. Br. J. Dermatol., 156: 32-37.
    CrossRef  |  Direct Link  |  
  230. Shaker, O., M. El-Raziky, K. Salama, H. Waheed, M. Taha and R. Talaat, 2007. HLA class II in atopic and non atopic members of asthmatic family pedigrees. Biochim. Clin., 31: 31-34.
    Direct Link  |  
  231. El-Asmer, M.F., T. Abdel-Aziz, A. Basheer, E. El-Daba, O. Shaker and D. El-Miligy, 2007. Molecular cloning and sequencing of disintegrin like domain from cerastes cerastes venoum gland. Egypt. J. Biochem. Mol. Biol., 25: 180-191.
  232. Abdel-Halim, H., M. Tawfik, R. Ahmed, W. El-Akel, S. Hamdy, O. Shaker and S. Talaat, 2007. Factors associated with liver steatosis in Egyptian patients with chronic HCV hepatitis. Kasr El Aini Med. J., 13: 33-44.
  233. Abdel-Halim, H., H.H. El-Demellawy and O. Shaker, 2007. Expression of telemorase activity and oxidative stress in Egyptian patients with hepato-cellular carcinoma. Egypt. J. Int. Med., 19: 99-108.
  234. Tawfic, S.O. and O. Shaker, 2006. Nerve growth factor in inflammatory acne vulgaris lesion. J. Egypt. Wom Dermatol. Soc., 3: 63-68.
  235. Shaker, O.G., W. Moustafa, S. Essmat, M. Abdel-Halim and M. El-Komy, 2006. The role of interleukin-12 in the pathogenesis of psoriasis. Clin Biochem., 39: 119-125.
  236. Shaker, O.G., M.A.A. El-Deen, M.T.A. El-Rahim and R.M. Talaat, 2006. Gene expression of e-selectin in tissue and its protein level in serum of breast cancer patients. Tumori., 92: 524-530.
  237. Shaker, O. and R. Youssef, 2006. Role of apoptosis stimulus factor and its ligand in the induction of apoptosis in some ultraviolet induced diseases. Dermatol. Online J., Vol. 12. .
    Direct Link  |  
  238. Shahin, A., A. Elsawaf, S. Ramadan, O. Shaker, M. Amin and M. Taha, 2006. Serum levels of tissue inhibitors of metalloproteinase 2 in patients with systemic sclerosis with duration more than 2 years: correlation with cardiac and pulmonary abnormalities. Mediators Inflamm., Vol. 2006. 10.1155/MI/2006/38458.
    CrossRef  |  Direct Link  |  
  239. Rateb, A.A.E., R.M. Youssef, R. Sobhi, S. El-Tahlawi, S.O. Tawfic and O. Shaker and S. Ali, 2006. Quantitative study of telomerase enzyme in psoriasis and mycosis fungoides. J. Egypt Wom Dermatol. Soc., 3: 75-80.
  240. Morsi, W.G., O.G. Shaker, E.F. Ismail, H.H. Ahmed and T.I. El-Serafi et al., 2006. HO-1 and VGEF gene expression in human arteries with advanced atherosclerosis. Clin. Biochem., 39: 1057-1062.
    CrossRef  |  Direct Link  |  
  241. Fouad, R., F. Halawa, O. Shaker, A. Hassouna and M, Badawi, 2006. Molecular detection of circulationg tumor cells in patients with HCC using AFP-mRNA and melanoma antigen gene-1 mRNA (MAGE-1 mRNA). Kasr El Aini Med. J., 12: 151-160.
  242. Esmat S., H. El-Sherif, S. Anwar, I. Fahmy, M. Elmenyawi and O. Shaker, 2006. Lipoprotein (a) and nitrites in Behcet's disease: relationship with disease activity and vascular complications. Eur. J. Dermatol., 16: 67-71.
    Direct Link  |  
  243. El-Komy, M.H.M. and O. Shaker, 2006. IL-18 expression in inflammatory acne vulagris: Another propionibacterium acnes induced cytokines? J. Egypt Wom Dermatol. Soc., 3: 81-85.
  244. Aziz, M.T.A., M.Z.A. Aziz, H.M. Atta, O.G. Shaker and M.M.A. Fattah et al., 2006. Screening for human papillomavirus (HPV) in Egyptian women by the second-generationhybrid capture (HC II) test. Med. Sci. Monit., 12: MT43-MT49.
    Direct Link  |  
  245. Abdel Fattah, M., E. Halawa and O. Shaker, 2006. Zinc levels in Egyptian infantile wheezers. The Gaz, Egypt. Paed., 54: 361-369.
  246. Zakaria, S., R. Fouad, O. Shaker, W. El-Akel and A. Hashem et al., 2005. The natural history of untreated symptomatic acute hepatitis C infection in Egypt. Arab J. Gastro., 6: 131-139.
  247. Shaker, O. and M.A.A. El-Deen, 2005. Apolipoprotein E gene polymorphism as a risk factor for atherosclerosis in Egyptians. Biochim. Clin., 29: 340-345.
  248. Shahin, Z., R. Youssef, H. El-Hadidi, O. Shaker, S. Esmat and A. Zayed, 2005. A study of polymerase chain reaction in the diagnosis of early mycosis fungoides. Egypt. J. Dermatol. Androl., 25: 69-80.
  249. Mohamed, T.A., M. Aziz, F. El-Asmer, O. Shaker and M. Manal et al., 2005. Heme oxygenase: Relationship to nitric oxide synthase/nitric oxide system in murine Schistosomiasis. Biochim. Clin., 29: 475-482.
  250. El-Aziz, M.T.A., M.M. Tarek, G.S. Olfat, H.A. Hanan, M.T.A. El-Rahim and A.M. Mostafa, 2005. Gene expression of maspin and multidrug resistance mRNAs in Egyptian breast cancer. Biochim. Clin., 29: 5-12.
    Direct Link  |  
  251. Aziz, M.T.A., O.G. Shaker, T. Mostafa, F. El-Asmar and H.M. Atta et al., 2005. Heme oxygenase gene expression in human azoospermic testicular tissue. Biochim. Clin., 29: 468-474.
  252. Abdel, A.M.T., M.F. El-Asmar, H.M. Atta, Y. Nassar and O.G. Shaker et al., 2005. Gene expression of heme oxygenase-1: Relationship to fibrogenic and apoptotic factors in murine schistosomiasis. J. Clin. Biochem. Nutr., 36: 67-78.
    CrossRef  |  Direct Link  |  
  253. Zaher, H., Shaker, O.G., N.H. El-Eishi, O.S. El-Safouri and M.M. Fawzi, 2004. Serologiocal study of matrix metalloproteinase-9 in systemic lupus erythematosus. J. Pan-Arab League Dermatol., 15: 109-118.
  254. Shaker, O.G., H.H Ahmed, H. El-Hadad and M.M. Fawzy, 2004. Matrix metalloproteinase-9 (MMP-9) in patients with chronic arterial occlusive disease. Kasr El Aini Med. J., 10: 63-70.
  255. El-Shamy, N., O. Gamil and A. Abdel-Hadi, 2004. Study of oxidative stress and anemia in chronic renal failure: The impact of erythropoietin supplementation. Egypt. J. Int. Med., 16: 71-80.
  256. El-Mofty M., W. Mostafa, S. Esmat, R. Youssef and M. Bousseila et al., 2004. Suggested mechanisms of action of UVA phototherapy in morphea: a molecular study. Photodermatol. Photoimmunol. Photomed., 20: 93-100.
    CrossRef  |  Direct Link  |  
  257. El-Hindawy, K.M., H. Kattab and O. Shaker, 2004. Does pentoxyfyline have a protective effect on renal ischemia-reperfusion? An experimental study in dogs. Kasr El Aini J. Surg., 5: 59-70.
  258. El-Hadad, H., M.M. Fawzy, O.G. Shaker, N.H. El-Eishi, H.H. El-Eishi, A.H. Soliman and F.H. El-Mahallawy, 2004. Parvovirus B19 viremia in Egyptian patients with systemic lupus erythematosus. Kasr El Aini Med. J., 10: 71-78.
  259. Abdel Rahman, M.M., M.A. El Tatawi, O.G. Shaker and M. Galal, 2004. Soluble intercellular adhesion molecule-1 and soluble interleukin-2 receptor as activity markers in some connective tissue diseases. Kasr El Aini Med. J., 10: 209-218.
  260. Youssef, R.M. and O.G. Shaker, 2003. The Role of prolactin and growth hormone in psoriasis. Egypt. J. Dermatol. Androl., 23: 91-100.
  261. Sobeih, S., R. Youssef, S. Esmat, M. Fawzi and O. Shaker, 2003. Evaluation of catalase and lipid peroxidase in the atio-pathogenesis of vitiligo. Egypt. J. Dermatol. Androl., 23: 29-40.
  262. Shaker, O.G., A.H. El-Salakawy and H.M. Nahed, 2003. Human parvovirus B19 and cytomegalovirus infections and thyroid auto-immunity in women with recurrent first trimester abortion. Biochim. Clin., 27: 20-28.
  263. Shaker, O., H. Weshahy, S. Esmat, S. Sobeih and W. Sabbouh, 2003. Herpes virus type 8 (HHV8) in non related Kaposi's sarcoma in Egyptian patients. J. Med. Mol. Biotechnol., 1: 54-72.
  264. Mourad, H., A. Ayad, S. Soultan and O. Shaker, 2003. Serum vascular endothelial growth factor levels in chronic liver diseases. Egypt. J. Int. Med., 15: 137-144.
  265. Hunter, N. and O. Shaker, 2003. NF-KB expression in psoriasis and cutaneous lichen planus. J. Pan Arab League Dermatol., 15: 227-233.
  266. Gobba, S., H. Atta, M. Amin, D. El-Meligy, O. Shaker, D. Sabry and M.T. Abdel-Aziz, 2003. Molecular detection of helicobacter pylori in liver tissue: A possible relation to ammonia encephalopathy. J. Med. Mol. Biotechnol., 1: 17-34.
  267. El-Zawahry, B., O. Shaker, S. Esmat, A. Zayed, N. Nagy, M. El-Bohy and A. Sharaf, 2003. Effectiveness of pulsed dye laser in the treatment of verrucae: A clinicopathological and molecular study. Egypt. J. Dermatol. Venereol., 23: 17-28.
  268. El-Mofty, M., S. Sobeih, W.Z. Mostafa, R. Youssef and H. El-Hadidi et al., 2003. Effect of low dose broad-band UVA on serum concentrations of procollagen I synthesis and degradation and procollagen III synthesis in morphea. Gulf J. Dermatol., 10: 15-25.
  269. El-Hosiny, N., H. Morad and O. Shaker, 2003. Serum vascular endothelial growth factor levels and vascular parameters in diabetic patients. Egypt. J. Int. Med., 15: 447-455.
  270. El-Hadidi, H., O. Shaker, H. El-Hadad, S. Fadl and S. Yassin, 2003. The role of beta endorphin and parathormone hormone in the pathogenesis of uremic pruritis. J. Pan-Arab League Dermatol., 14: 43-50.
  271. El-Eishi, N., O. Shaker, H. Morad, A. Foda and M. Fawzy, 2003. Serum interleukin 6 and C reactive protein levels and disease activity in systemic lupus erythematosus. J. Pan Arab League Dermatol., 14: 127-134.
  272. Askar, A.H., H. Khattab and O. Shaker, 2003. Pravastatin and its effect on renal reperfusion injury in an experimental model in dogs. Kasr El-Aini J. Surg., 4: 1-10.
  273. Abdel-Aziz, M.T., M.F. El-Asmar, D. El-Miligy, H. Atta and O. Shaker et al., 2003. Retrovirus-mediated human heme oxygenase-1 (HO-1) gene transfer into rat endothelial cells: The effect of HO-1 inducers on the expression of cytokines. Int. J. Biochem. Cell Biol., 35: 324-332.
    CrossRef  |  Direct Link  |  
  274. Abdel-Aziz, M.T., G.A. Tawadrous, Y. Nassar, O.G. Shaker and A. El-Ansary et al., 2003. Diagnosis of extrapulmonary tuberculosis using immunoglobulins against A60antigen. J. Med. Mol. Biotechnol., 1: 35-53.
  275. Youssef, R., O. Shaker, S. Sobeih, H. Mashaly and W.Z. Mostafa, 2002. Detection of herpes simplex virus DNA in serum and oral secretions during acute recurrent herpes labialis. J. Dermatol., 29: 404-410.
    CrossRef  |  Direct Link  |  
  276. Shaker, O., H. Hosny and M. El-Razky, 2002. Serum TGF-B1 and C-erb neu-oncoprotein levels in cases of HCV and HCC. Arab J. Lab. Med., 28: 105-115.
  277. Shahin, A.A., O.G. Shaker, N. Kamal, H.A. Hafez, W. Gaber and H.A. Shahin, 2002. Circulating interleukin-6, soluble interleukin-2 receptors, tumor necrosis factor alpha, and interleukin-10 levels in juvenile chronic arthritis: correlations with soft tissue vascularity assessed by power Doppler sonography. Rheumatol. Int., 22: 84-88.
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  278. El-Kerdawy, H., A. Omran, H. Okasha and O.G. Shaker, 2002. The effect of ketamine on the soluble adhesive molecules after cardiopulmonary bypass in patients undergoing coronary artery bypass grafting surgery. Egypt. J. Anesth, 18: 45-51.
  279. El-Haddad, H., O. Shaker, S.H. El-Assat and H.F. Awad, 2002. Homocysteine, B12& folic acid estimation in diabetic complications. Kasr El Aini Med. J., 8: 107-116.
  280. El-Hadad, H.E., O.G. Shaker and H.H. Ahmed, 2002. MMP1, MMP2 and tissue inhibitor MMP1 in diabetic nephropathy. Kasr El Aini Med. J., 8: 197-210.
  281. Abdel-Aziz, M.T., M.F. Al-Asmar, H. Atta, O.G. Shaker and F. Hanan et al., 2002. Effect of inducers of heme oxygenase-1(HO-1) on eicosanoids, cAMP and cGMP levels in rat endothelial cells. J. Biochim. Clin., 26: 352-357.
  282. Zaher, H., M. Bousseila, S. Sobeih, N. Hunter, M. El-Khashab and O.G. Shaker, 2001. Tumor necrosis factor receptor II (TNF-RII) in cutaneous and oral lichen planus: Serum and tissue levels. Egypt. J. Dermatol. Androl., 21: 81-88.
  283. Sobeih, S.A., R.M. Youssef, H. El-Hadidi and O. Shaker, 2001. Role of nitric oxide in psoriasis and atopic dermatitis. J. Pan-Arab League Dermatol., 12: 33-41.
  284. Sobeih, S., R. Youssef, M. Fawzi, M. El-Khashab and O.G. Shaker, 2001. Evaluation of interleukin 10 and interferon gamma in progression of mycosis fungoides. Egypt. J. Dermatol. Androl., 21: 23-32.
  285. Omran, A. and O. Shaker, 2001. Comparative study of the effects of inhalational anaesthesia (isofluran) and total intra-venous anaesthesia (propofol) on the changes of interleukin-8 and cortisol hormone in major abdominal surgery. Med. J. Cairo Univ., 69: 233-239.
  286. El-Batrawy, F.A., E. Abd El-Monem, O.G. Shaker, S.A. Fadda and D.A. Sourour, 2001. Comparative study between the effect of carvedilol and metoprolol on doxorubicin induced nephropathy. J. Egypt. Soc. Pharmacol. Exp. Ther., 20: 531-561.
  287. Zaher, H.A., H. El-Hadidi, O.G. Shaker, S.A. Sobeih and N. Hunter, 2000. Serum level of soluble tumer necrosis factor alpha receptor type II in systemic lupus erythematosus. J. Pan-Arab League Dermatol., 11: 67-78.
  288. Youssef, R., S. Ramadan, N. Mongy and O. Shaker, 2000. Is hypo or hyper ferremia related to recurrent skin infections? Egypt. J. Dermatol. Androl., 20: 31-36.
  289. Youssef, R., M. Abou Zeid, H. Mahmoud and O. Shaker, 2000. Role of UVB phototherapy on the level of serum and skin retinol content in uremic patients suffering from uremic pruritis. J. Pan-Arab League Dermatol., 11: 9-19.
  290. Shaker, O.G., H.H. Ahmed and H. El-Hadidy, 2000. Soluble interleukin-2 receptor alpha in sera and skin tissue fluid of patients with vitiligo. Bull. Egypt. Soc. Physiol. Sci., 20: 362-380.
  291. Okasha, S.H., H.H. Okasha and O.G. Shaker, 2000. Incidence of hepatitis C by PCR in diabetics with raised transaminases. Arab J. Gastroenterol., 1: 75-85.
  292. El-Tahlawy, S., S. Esmat, M.A. Bosseila, O. Shaker and T. Abdel Reheem, 2000. Detection and localization of human papilloma virus (HPV) in skin tags by in situ hybridization. Egypt. J. Dermatol. Androl., 20: 81-88.
  293. El-Batanouny, H., M.H. El-Dessouky, M.F. Reda, Z.H. El-Kirdassy, A. Khalil and O. Shaker, 2000. Biochemical assessment of liver cell regeneration in normal versus Bilharzial livers after partial hepatectomy. Egypt. J. Surg., 19: 106-114.
  294. Abdel Aziz, M.T., L. Ahmed, H. Salama, O. Shaker, H. Atta, A. Khalil and D.T. Abdel Aziz, 2000. Molecular quantitation of HCV RNA in liver tissue and serum: Relationship to disease activity. Egypt. J. Biochem. Mol. Biol., 18: 229-248.
  295. Youssef, R.M., S.M. Esmat and O.G. Shaker, 1999. The effect of chronic solar exposure on oxidative damage and the ferritin mediated antioxidant protective mechanism in the skin. Egypt. J. Derm. Ven., 19: 3-8.
  296. Tawadrous, G.A., M. El-Zein, O.G. Shaker and A. Hassouna, 1999. Serum leptin levels in healthy active, passive and nonsmokers subjects relation to cotinine. Bull. Egypt. Soc. Physiol. Sci., 19: 33-41.
  297. Soliman, M.M., A.A. Rateb, O.G. Shaker and N.A. Sidki, 1999. A comparative study of different diagnostic techniques of leprosy. Egypt. J. Derm. Ven., 19: 31-38.
  298. Seliem, Z.S., L.A. Seliem and O.G. Shaker, 1999. Detection of enteroviruses using PCR technique in patients with idiopathic dilated cardiomyopathy. J. Arab Child, 10: 139-150.
  299. El-Badawy, A., D. El-Sebaie, M. Bashir and O. Shaker, 1999. Estimation of serum iron, total iron binding capacity, folic acid and vitamin B 12 in the sera of Egyptian neonates. Gaz. Egypt. Paed., 47: 113-120.
  300. El-Ayadi, A., A. Kaddah, O. Shaker and E. Abdel Wahed, 1999. Nitric oxide derivatives in induced sputum in asthmatic children. Med. J. Cairo Univ., 67: 1141-1152.
  301. Shaker, O.G., H. Saker, Z. Mahmoud and Z. Yousry, 1998. Lipid peroxidation and trace elements abnormalities in patients with chronic renal failure. Egypt. J. Med., 7: 563-576.
  302. Shaker, O., S. Abo-Elyazeed, H. Sakr and S. El-Said, 1998. In vitro production of interleukin-10 by peripheral blood mononuclear cells in rheumatoid arthritis and systemic lupus erythematosus. Egypt. J. Internal Med., 7: 349-357.
  303. Shaker, O., H.A. Fadl, M.K. El-Hatw, 1998. Prevalence of hepatitis C virus RNA in patients with chronic renal diseases. Eastern Mediterranean Health J., 4: 548-553.
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  304. Shaker, O., D.M.T. Abdel-Aziz, M.A.B. Nayel and S. Mahfouz, 1998. Detection of Chlamydia trachomatis by in-situ polymerase chain reaction in cases of mucopurulent endocervicitis. Egypt. J. Biochem., 16: 63-80.
  305. Riad, R.I., O. Shaker, N. El-Abiad and H. Waheed, 1998. Prevalence of hepatitis G virus infection during pregnancy and its vertical transmission to the newborn. Med. J. Cairo Univ., 66: 391-395.
  306. Ismail, Z., N. El-Shamy, S. Okasha and O.G. Shaker, 1998. Evaluation of the oxidative stress in type II diabetics with and without vascular complications and in non-diabetic obese subjects. Egypt. J. Med., 7: 161-176.
  307. Hegazy, M., O. Awad, O. Shaker, M.A. El-Sattar, A.A. El-Fadle and D.M.T. Abd-El-Aziz, 1998. A sensitive molecular method for the identification of skeletal material of different species. Benha Med. J., 15: 91-99.
  308. El-Hatw, M.K., H. Salah, A. Irris, O. Shaker and S. Wagieh, 1998. Urinary Interleukin-8 and Tc99m DMSA scintigraphy as diagmnostic parameters in evaluating children with recurrent urinary tract infections. Gaz. Egypt. Paed., 46: 89-100.
  309. Aboul-Fadl, H., O.G. Shaker, B. Makin and F. Salem, 1998. Human B19 parvovirus infection in an obstetric Egyptian population as detected by PCR examination. Egypt. J. Med. Microbiol., 7: 465-470.
  310. Aboul-Fadl, H., O. Shaker, M. El-Hatw and M. Abdel-Aziz, 1998. PCR as a rapid and early detection method of CMV-DNA in patients with chronic renal diseases. Egypt. J. Med. Microbiol., 7: 421-427.
  311. Abd-El-Aziz, M., O. Shaker, D.M.T. Abd-El-Aziz and M.Z. Abd-El-Aziz, 1998. Concurrent CMV and HPV infection in benign and malignant cervical lesions among Egyptian women. Egypt. J. Biochem., 16: 117-130.
  312. Zahran, M., H. Maged, A. El-Sawy and O. Shaker, 1997. Trace elements and lipid peroxidation abnormalities in patients with chronic liver failure. Gaz. Egypt. Paed., 45: 77-89.
  313. Shaker, O., K.A. El-Khalik and N. Fahmy, 1997. Diagnosis of congenital cytomegalovirus and rubella infection by PCR. Bull. Egypt. Soc. Physiol. Sci., 17: 223-237.
  314. Moftah, N., S.I. Enany and O. Shaker, 1997. Estimation of seminal catalase activity in infertile patients. Egypt. J. Androl. Reprod., 17: 123-134.
  315. Ibrahim, B., G. Rashed and O. Shaker, 1997. Detection of hepatitis C virus RNA in liver tissue of chronic hepatitis conditions by reverse transcription polymerase chain reaction in situ hybridization (RT-PCR-ISH). Med. J. Cairo Univ., 65: 881-891.
  316. Helal, N.F., L. Mohsen, O. Shaker and K.B. Nasser, 1997. Blood and exchange transfusion as a risk for acquired hepatitis C virus in neonates. Med. J. Cairo Univ., 65: 447-453..
  317. Helal, N.F., F. Fadel, O. Shaker and D. Khairy, 1997. Risk of transfusion acquired cytomegalovirus infection in neonates subjected to blood exchange transfusion. Med. J. Cairo Univ., 65: 15-23.
  318. Hala, F., H. Maged, O. Afify, N. El-Abiad and O.G. Shaker, 1997. Gene expression of IL-10 in SLS in children. Gaz. Egypt. Paed., 45: 129-136.
  319. Fahmy, N., L. Abdel-Motteleb, O. Shaker and M. Ramadan, 1997. Herpes simplex viral encephalitis (HSE): Clinical and laboratory evaluation. J. Arab Child, 8: 443-454.
  320. El-Zawahry, M.B. and O. Shaker, 1997. The application of different molecular biology techniques in the diagnosis of some skin diseases. Egypt. J. Dermatol. Venereol., 17: 43-48.
  321. El-Hafez, M.A.A., S.M. Naguib, M. Nassar, O. Shaker and M. Saleh, 1997. Diurnal variations of nitric oxide release in relation to liver cirrhosis of different stages with progressive endotoxaemia. Az. J. Microbiol., 37: 67-78.
  322. El-Badawy, A., A. Edris, M. Moustafa and O. Shaker, 1997. Human parvovirus B-19 infection in Egyptian anemic neonates. Kasr El-Aini Med. J., 3: 215-226.
  323. Abdel-Aziz, M.T., O. Shaker and L.A. Motteleb, 1997. A comparative study of the conventional procedures and polymerase chain reaction for diagnosis of tuberculus pleural effusion. Bull. Egypt. Soc. Physiol. Sci., 17: 111-118.
  324. Salem, A., L. Mansour and O. Shaker, 1996. Herps group viruses: Diagnosis by polymerase chain reaction in guillan barre syndrome and transverse myelitis. New J. Med., 14: 111-119.
  325. Mostafa, T., F. Halawa and O. Shaker, 1996. Seminal plasma IL-2 and IL-8 in leukocytospermia. Egypt. J. Androl. Reprod., 10: 41-52.
  326. Mansour, L., S. Tatawi and O. Shaker, 1995. Myoclonic epilepsy in infants and children: Neuroimaging and metabolic studies. Kasr El-Aini Med. J., 2: 59-80.
  327. Abdel-Aziz, M.T., A. Kamel, H. Kamel, M. Kamel and M.R. Hamza et al., 1995. Minimal residual disease following allogeneic bone marrow transplantation in chronic myeloid leukemia. J. Egypt. Nat. Canc. Inst., 7: 183-190.
  328. Abdel-Aziz, M.T., A.M. Rizk, W.M. El-Harrizi, H.M. Atta and O.G. Shaker et al., 1994. Uptake of 65Zn by schistosoma mansoni-infectet liver. Bull. Egypt. Soc. Physiol. Sci., 14: 170-185.
  329. Abdel Aziz, M.T., M. Saber, M. Kamel and O. Shaker, 1992. Gene expression of IL-6 in cases of human Schistosomiasis. Egypt. J. Biochem., 10: 210-219.