Dr. Attalla Farag El-Kott
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Dr. Attalla Farag El-Kott

Professor
Biology Dept., Faculty of Science, King Khalid University, Abha, KSA


Highest Degree
Ph.D. in Histology from Mansoura University, Egypt

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Area of Interest:

Molecular Sciences
100%
Histology
62%
Genetics
90%
Cell Biology
75%
Histopathology
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Shati, A.A. and A.F. El‐Kott 2021. Acylated Ghrelin Protects against Doxorubicin‐Induced Nephropathy by Activating Silent Information Regulator 1. BCPT 128: 805-821.
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  2. Shati, A.A. and A.F. El-Kott 2021. Resolvin D1 Protects Against Cadmium Chloride-induced Memory Loss and Hippocampal Damage in Rats: A Comparison with Docosahexaenoic Acid. Hum. Exp. Toxicol. 10.1177/09603271211038739.
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  3. Shaldoum, F., A.F. El‐kott, M.M.A. Ouda and E.M. Abd‐Ella 2021. Immunomodulatory Effects of Bee Pollen on Doxorubicin‐Induced Bone Marrow/Spleen Immunosuppression in Rat. J. Food Biochem. 10.1111/jfbc.13747.
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  4. Nazish, A., Fozia, B. Khattak, T.A. Khan and I. Ahmad et al. 2021. Antinematode Activity of Abomasum Bacterial Culture Filtrates against Haemonchus contortus in Small Ruminants. Anim. 10.3390/ani11061843.
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  5. Massoud, D., A.F. El-kott and F. Shaldoum 2021. Comprehensive Histochemical and Stereological Study of the Parotid and Sublingual Salivary Glands in Caucasian Squirrel (Sciurus anomalus). Acta Histochem., Vol. 123. 10.1016/j.acthis.2021.151742.
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  6. Komal, A., M. Noreen and A.F. El-Kott 2021. TLR3 Agonists: RGC100, ARNAX, and Poly-IC: A Comparative Review. Immunol. Res. 69: 312-322.
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  7. El-kott, A.F., E.R. ElBealy, A.S. Alshehri, A.E. El-Kenawy and H.S. Khalifa et al. 2021. Salidroside Induces Cell Apoptosis and Inhibits the Invasiveness of HT29 Colorectal Cells by Regulating Protein Kinase R, NF-κb and STAT3. CBM 31: 13-25.
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  8. Alshehri, A.S., A.F. El-kott, A.E. El-Kenawy, H.S. Khalifa and A.M. AlRamlawy 2021. Cadmium Chloride Induces Non-Alcoholic Fatty Liver Disease in Rats by Stimulating miR-34a/SIRT1/FXR/p53 Axis. Sci. Total Environ. 10.1016/j.scitotenv.2021.147182.
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  9. Abumandour, M.M.A., N.E.R. El‐Bakary, E.R. Elbealy, A. El‐Kott and K. Morsy et al. 2021. Ultrastructural and Histological Descriptions of the Oropharyngeal Cavity of the Rock Pigeon Columba livia dakhlae with Special Refer yo its Adaptive Dietary Adaptations. Microsc. Res. Tech. 10.1002/jemt.23870.
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  10. ALTamimi, J.Z., M.N. BinMowyna, N.A. AlFaris, R.I. Alagal, A.F. El-kott and A.M. AL-Farga, 2021. Fisetin protects against streptozotocin-induced diabetic cardiomyopathy in rats by suppressing fatty acid oxidation and inhibiting protein kinase r. Saudi Pharm. J., 29: 27-42.
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  11. Elsaid, F.G., M.A. Alshehri, A.A. Shati, M.A. Al‐Kahtani and A.S. Alsheri et al., 2020. The anti‐tumorigenic effect of Ellagic acid in SKOV‐3 ovarian cancer cells entails activation of autophagy‐mediated by inhibiting Akt and activating AMPK. Clin. Exp. Pharmacol. Physiol., 10.1111/1440-1681.13338.
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  12. El-kott, A.F., M.M. Bin-Meferij, S.M. Eleawa and M.M. Alshehri, 2020. Kaempferol protects against cadmium chloride-induced memory loss and hippocampal apoptosis by increased intracellular glutathione stores and activation of PTEN/AMPK induced inhibition of Akt/mTOR signaling. Neurochem. Res., 45: 295-309.
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  13. El-kott, A.F., A.S. Alshehri, H.S. Khalifa, A.E.k.M. Abd-Lateif and M.A. Alshehri et al., 2020. Cadmium chloride induces memory deficits and hippocampal damage by activating the JNK/p66Shc/NADPH oxidase axis. Int. J. Toxicol., 39: 477-490.
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  14. El-kott, A.F., A.E.M. Abd-Lateif, H.S. Khalifa, K. Morsy and E.H. Ibrahim et al., 2020. Kaempferol protects against cadmium chloride-induced hippocampal damage and memory deficits by activation of silent information regulator 1 and inhibition of poly (ADP-Ribose) polymerase-1. Sci. Total Environ., Vol. 728. 10.1016/j.scitotenv.2020.138832.
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  15. Eid, R.A., S.A. Alharbi, A.F. El-kott, S.M. Eleawa and M.S.A. Zaki et al., 2020. Exendin-4 ameliorates cardiac remodeling in experimentally induced myocardial infarction in rats by inhibiting PARP1/NF-κB axis in a SIRT1-dependent mechanism. Cardiovasc. Toxicol., 10.1007/s12012-020-09567-5.
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  16. Eid, R.A., M.S.A. Zaki, M.A. Eldeen, M.M. Alshehri, A.A. Shati and A.F. El‐kott, 2020. Exendin‐4 protects the hearts of rats from ischemia/reperfusion injury by boosting antioxidant levels and inhibition of JNK/p66 Shc/NADPH axis. Clin. Exp. Pharmacol. Physiol., 10.1111/1440-1681.13299.
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  17. Eid, R.A., M.M. Bin-Meferij, A.F. El-kott, S.M. Eleawa and M.S.A. Zaki et al., 2020. Exendin-4 protects against myocardial ischemia-reperfusion injury by upregulation of SIRT1 and SIRT3 and activation of AMPK. J. Cardiovasc. Trans. Res., 10.1007/s12265-020-09984-5.
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  18. Eid, R.A., M.A. Khalil, M.A. Alkhateeb, S.M. Eleawa and M.S.A. Zaki et al., 2020. Exendin-4 attenuates remodeling in the remote myocardium of rats after an acute myocardial infarction by activating u03b2-arrestin-2, protein phosphatase 2A, and glycogen synthase kinase-3 and inhibiting u03b2-catenin. Cardiovasc. Drugs Ther., 10.1007/s10557-020-07006-9.
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  19. Dajem, S.B., K. Morsy, M. Alshehri, A. El-kott, E. Ibrahim, H. El-Mekkawy and R. Abdel-Gaber, 2020. Morphology and molecular taxonomy of the tongue worm, genus Raillietiella (pentastomida) from the lungs of berber skinks Eumeces schneideri (scincidae): first report. Rev. Argent. Microbiol., 10.1016/j.ram.2020.06.010.
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  20. Aly, I., E.H. Ibrahim, R.S. Hamad, H.E.L. Sayed and S.M.N. Attiyah et al., 2020. The protective role of toll-like receptor agonist monophosphoryl lipid A against vaccinated murine schistosomiasis. Acta Parasitol., 10.2478/s11686-020-00204-3.
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  21. Al-Kahtani, M., M.M. Abdel-Daim, A.A. Sayed, A. El-Kott and K. Morsy, 2020. Curcumin phytosome modulates aluminum-induced hepatotoxicity via regulation of antioxidant, Bcl-2, and caspase-3 in rats. Environ. Sci. Pollut. Res., 27: 21977-21985.
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  22. Aboelwafa, H.R., A.F. El-kott, E.M. Abd-Ella and H.N. Yousef, 2020. The possible neuroprotective effect of silymarin against aluminum chloride-prompted alzheimer’s-like disease in rats. Brain Sci., 10.3390/brainsci10090628.
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  23. Abdel-Daim, M.M., A.I. Abushouk, S.G. Bungu0103u, M. Bin-Jumah and A.F. El-kott et al., 2020. Protective effects of thymoquinone and diallyl sulphide against malathion-induced toxicity in rats. Environ. Sci. Pollut. Res., 27: 10228-10235.
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  24. Shati, A.A. and A.F. El-kott, 2019. Acylated ghrelin prevents doxorubicin-induced cardiac intrinsic cell death and fibrosis in rats by restoring IL-6/JAK2/STAT3 signaling pathway and inhibition of STAT1. Naunyn-Schmiedeberg's Arch. Pharmacol., 392: 1151-1168.
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  25. Shati, A.A. and A.F. El-kott, 2019. Acylated ghrelin prevents doxorubicin-induced cardiac intrinsic cell death and fibrosis in rats by restoring IL-6/JAK2/STAT3 signaling pathway and inhibition of STAT1. Naunyn-Schmiedeberg’s Arch. Pharmacol., 392: 1151-1168.
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  26. Morsy, K., M. Al-Kahtani, A. Shati, A. El-Kott, R. Abdel-Gaber and M. Fol, 2019. New host and locality record of Parapharyngodon japonicus (Nematoda: Oxyuroidea) from the Egyptian changeable lizard Agama mutabilis (Agamidae): A light and scanning electron microscopy. Helminthologia, 56: 22-29.
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  27. Hashem, M., S.A. Alamri, A.A. Shathan, S.R.Z. Alshehri, Y.S. Mostafa and A. El-kott, 2019. Antifungal efficiency of wild plants against human-opportunistic pathogens. J. de Mycologie Médicale, 29: 168-173.
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  28. El‐kott, A.F., M.A. Al‐kahtani and A.A. Shati, 2019. Calycosin induces apoptosis in adenocarcinoma HT 29 cells by inducing cytotoxic autophagy mediated by SIRT 1/AMPK‐induced inhibition of Akt/mTOR. Clin. Exp. Pharmacol. Physiol., 46: 944-954.
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  29. El‐kott, A.F., A.A. Shati, M.A. Al‐kahtani and S.A. Alharbi, 2019. The apoptotic effect of resveratrol in ovarian cancer cells is associated with downregulation of galectin‐3 and stimulating miR‐424‐3p transcription. J. Food Biochem., Vol. 43, No. 12. 10.1111/jfbc.13072.
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  30. El‐Zeftawy, M., D. Ghareeb, E.R. El-Bealy, R. Saad and S. Mahmoud et al., 2019. Berberine chloride ameliorated PI3K/Akt‐p/SIRT‐1/PTEN signaling pathway in insulin resistance syndrome induced in rats. J. Food Biochem., Vol. 43, No. 12. 10.1111/jfbc.13049.
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  31. El-kott, A.F., A.A. Shati, M.A. Al-kahtani and S. Alqahtani, 2019. Acylated ghrelin renders chemosensitive ovarian cancer cells resistant to cisplatin chemotherapy via activation of the PI3K/Akt/mTOR survival pathway. Anal. Cell. Pathol., 2019: 1-12.
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  32. Eid, R.A., S.M. Eleawa, M.A. Alkhateeb, H. Aldera and M.S.A. Zaki et al., 2019. Chronic consumption of a high‐fat diet rich in corn oil activates intrinsic cell death pathway and induces several ultrastructural changes in the atria of healthy and type 1 diabetic rat. Clin. Exp. Pharmacol. Physiol., 46: 1111-1123.
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  33. Eid, R.A., M.A. Alkhateeb, S.M. Eleawa, M.S.A. Zaki and A.F. El-kott et al., 2019. Fas/FasL-mediated cell death in rat's diabetic hearts involves activation of calcineurin/NFAT4 and is potentiated by a high-fat diet rich in corn oil. J. Nutr. Biochem., 68: 79-90.
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  34. Eid, R.A., M.A. Alkhateeb, M. Al-Shraim, S.M. Eleawa and A.S. Shatoor et al., 2019. Ghrelin prevents cardiac cell apoptosis during cardiac remodelling post experimentally induced myocardial infarction in rats via activation of Raf-MEK1/2-ERK1/2 signalling. Arch. Physiol. Biochem., 125: 93-103.
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  35. Eid, R.A., M.A. Alkhateeb, A.F. El‐Kott, S.M. Eleawa and M.S.A. Zaki et al., 2019. A high‐fat diet rich in corn oil induces cardiac fibrosis in rats by activating JAK2/STAT3 and subsequent activation of ANG II/TGF‐1β/Smad3 pathway: The role of ROS and IL‐6 trans‐signaling. J. Food Biochem., Vol. 43, No. 8, 10.1111/jfbc.12952.
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  36. El-kott, A.F. and M.M. Bin-Meferij, 2018. Suppressive effects of capsaicin against N-nitrosomethylurea-induced mammary tumorigenesis in rats. Biomed. Pharmacother., 98: 673-679.
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  37. Eid, R.A., M.S.A. Zaki, M. Al-Shraim, S.M. Eleawa and A.F. El-kott et al., 2018. Subacute ghrelin administration inhibits apoptosis and improves ultrastructural abnormalities in remote myocardium post-myocardial infarction. Biomed. Pharmacother., 101: 920-928.
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  38. Eid, R.A., M.A. Alkhateeb, S. Eleawa, F.H. Al-Hashem and M. Al-Shraim et al., 2018. Cardioprotective effect of ghrelin against myocardial infarction-induced left ventricular injury via inhibition of SOCS3 and activation of JAK2/STAT3 signaling. Basic Res. Cardiol., Vol. 113. 10.1007/s00395-018-0671-4.
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  39. El-Kott, A.F. and M.M. Bin-Meferij, 2015. Use of Arctium lappa extract against acetaminophen-induced hepatotoxicity in rats. Curr. Ther. Res., 77: 73-78.
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  40. Ouhtit, A., M.F. Ismail, A. Othman, A. Fernando and M.E. Abdraboh et al., 2014. Chemoprevention of rat mammary carcinogenesis by Spirulina. Am. J. Pathol., 184: 296-303.
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  41. El-Bediwi, A.B., M. Saad, A.F. El-kott and E. Eid, 2012. Influence of electromagnetic radiation produced by mobile phone on some biophysical blood properties in rats. Cell Biochem. Biophys., 65: 297-300.
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  42. El-Meghawry El-Kenawy, A., A.F. El-Kott and M. Hassan, 2008. Heat Shock Protein Expression Independently Predicts Survival Outcome in Schistosomiasis-Associated Urinary Bladder Cancer. Int. J. Biol. Markers, 23: 214-218.
    PubMed  |  Direct Link  |  
  43. El-Kott, A.F., 2008. Ki-67 and P53 expression of melatonin hepatoprotective effects against toxicity of carbon tetrachloride in rats. Res. J. Med. Med. Sci., 3: 53-59.
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  44. El-Kott, A.F. and M.M. Bin-Meferij, 2008. Influence of green tea on haematological and lung histological disorders induced by malathion in rats. Res. J. Environ. Toxicol., 2: 85-91.
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  45. El-Kott, A.F. and A.A. Owayss, 2008. Protective effects of propolis against the amitraz hepatotoxicity in mice. J. Pharmacol. Toxicol., 3: 402-408.
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  46. EL-Kenawy, A.E.M., A.F. EL-kott and M.S. Hasan, 2008. Heat shock protein expression independently predicts survival outcome in schistosomiasis-associated urinary bladder cancer. Int. J. Biol. Markers, 23: 214-218.
    CrossRef  |  Direct Link  |  
  47. El-Kott, A.F., 2007. Flow cytometry and KI67 expression in rat's urinary bladder carcinogenesis treated with Allium sativum. Cancer Ther., 5: 185-192.
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  48. Hamed, S.M., A.E. El-Kenawy, A.F. El-Kott, F. El-Housini Moustafa and H. Abol-Enein, 2006. Schistosoma-induced amyloidosis in hamsters is gender-dependent. Int. Urol. Nephrol., 38: 707-712.
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  49. El-Meghawry El-Kenawy, A., A.F. El-kott, M.M. Bin-Meferij and E.M. El-Gamal, 2006. Expressions of epidermal growth factor receptor, matrix metalloproteinase-2 and matrix metalloproteinase-9 in bladder carcinoma. J. Boil. Sci., 6: 911-915.
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  50. El-Meghawry El-Kenawy, A., A.F. El-Kott, S.M. Hamed and M. Kuroki, 2006. Prognostic value of carcinoma-associated antigen mk-1 in urinary bladder carcinoma. Int. J. Biol. Markers, 21: 170-174.
    PubMed  |  Direct Link  |  
  51. El-Kott, A.F., M.F. Ismaeil, M.M. El-Moneim and M.A. El-Baz, 2006. Histogenesis of human renal cell carcinoma by using electron microscopy and immunohistochemical techniques. Int. J. Urol. Nephrol., 37: 439-445.
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  52. El-Kott, A.F., M.A. El-Baz and A.A. Mokhtar, 2006. Proliferating Cell Nuclear Antigen (PCNA) overexpression and microvessel density predict survival in the urinary bladder carcinoma. Int. J. Urol. Nephrol., 38: 237-242.
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  53. El-Kott, A.F., E.M. El-Gamal and A.M. Khalil, 2006. Immunohistochemical study of inducible nitric oxide and its prognosis in schistosomasis associated urinary bladder carcinoma. J. Boil. Sci., 6: 1098-1102.
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  54. EL-Kenawy, A.E.M., A.F. EL-kott, S.M. Hamed and M. Kuroki, 2006. Prognostic value of carcinoma-associated antigen MK-1 in urinary bladder carcinoma. Int. J. Biol. Marker, 21: 170-174.
    CrossRef  |  
  55. El-Meghawry, A.E.K., M. Lotfy, A. El-Kott and M. El-Shahat, 2005. Significance of Matrix Metalloproteinase 9 and CD34 Expressions in Esophageal Carcinoma. J. Clin. Gastroenterol., 39: 791-794.
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  56. El-Meghawry El-Kenawy, A., M. Lotfy, A. El-Kott and M. El-Shahat, 2005. Significance of matrix metalloproteinase 9 and CD34 expressions in esophageal carcinoma: correlation With DNA content. J. Clin. Gastroenterol., 39: 791-794.
    PubMed  |  Direct Link  |  
  57. El-Kott, A.F., A.M. Khalil and A. El-Meghawry El-Kenawy, 2004. Immunohistochemical expressions of upa and its receptor upar and their prognostic significant in urinary bladder carcinoma. Int. Urol. Nephrol., 36: 417-423.
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  58. El-Kenawy, A.M., A.F. El-Kott and A.M. Khalil 2003. Prognostic value of P53 and mdm2 expression in bilharziasis-associated squamous cell carcinoma of the urinary bladder. Int. J. Biol. Markers, 18: 284-289.
    PubMed  |  Direct Link  |  
  59. EL-Meghawry A.E.K., A.F. EL-kott and A.M. Khalil, 2003. Prognostic value of p53 and MDM2 expression in bilharziasis-associated squamous cell carcinoma of the urinary bladder. Int. J. Biol. Marker, 18: 284-289.
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