Dr. George  Aggelis
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Dr. George Aggelis

Associate Professor
University of Patras, Greece


Highest Degree
Doctorat in Microbial Biochemistry from Universite des Sciences et Techniques du Languedoc, France

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Biography

Dr. George Aggelis is currently working as Associate Professor of Microbiology Head of the Unit of Microbiology Division of Genetics, Cell Biology & Development Department of Biology University of Patras, Greece. He received his Doctorate degree in Microbial Biochemistry from Universite des Sciences et Techniques du Languedoc, France in 1989. His area of interest related to Single Cell Oil, Microbial (yeast, fungal, algal) Lipids Biosynthesis and Biotechnology; Polyunsaturated Fatty Acids; Organic Acids; Degradation of Phenolics; Microbial Metabolism of Glycerol, Methanol, Fatty Acids; and Modeling. He is also serving as member of editorial board in number of journals. He is member of Greek Agro-technical Chamber; Franco-Hellenic Scientific and Technical Society; Greek Society of Biotechnology; Food Science and Technology Greek Society; Greek Forum for the Science and Technology of Lipids; Society of Chemical Industry – London, and Hellenic Society of MikroBioKosmos. He also worked on 25 research projects, 13 projects as Principal Investigator. He also participated in 10 meetings. He supervised 5 Post-doc Researchers, 8 PhD, 4 MSc and more than 40 BS students. He also participated in number of scientific and administrative committees. He has published (2) books, (4) book chapters, (7) review papers, (92) research papers, (1) patent, (37) participations in international conferences, (72) participations in national and international meetings, and (8) articles in Greek journals contributed as author/co-author.

Area of Interest:

Biomedical Sciences
100%
Applied Microbiology
62%
Biodegradation
90%
Modelling
75%
Oleaginous Microorganisms
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Tchakouteu, S.S., O. Kalantzi, C.H. Gardeli, A.A. Koutinas, G. Aggelis and S. Papanikolaou, 2015. Lipid production by yeasts growing on biodiesel-derived crude glycerol: Strain selection and impact of substrate concentration on the fermentation efficiency. J. Applied Microbiol., 118: 911-927.
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  2. Moustogianni, A., S. Bellou, I.E. Triantaphyllidou and G. Aggelis, 2015. Feasibility of raw glycerol conversion into single cell oil by Zygomycetes under non-aseptic conditions. Biotechnol. Bioeng., 112: 827-831.
    Direct Link  |  
  3. Economou, C.N., N. Marinakis, M. Moustaka-Gouni, G. Kehayias, G. Aggelis and D.V. Vayenas, 2015. Lipid production by the filamentous cyanobacterium Limnothrix sp. growing on a synthetic wastewater in suspended- and attached-growth photobioreactor systems. Ann. Microbiol. (In Press). 10.1007/s13213-014-1032-7.
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  4. Alakhras, R., S. Bellou, G. Fotaki, G. Stepanou, N.A. Demopoulos, S. Papanikolaou and G. Aggelis, 2015. Fatty acid lithium salts from Cunninghamella echinulata have cytotoxic and genotoxic effects on HL-60 human leukemia cells. Eng. Life Sci., 15: 243-253.
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  5. Tchakouteu, S.S., A. Chatzifragkou, O. Kalantzi, A.A. Koutinas, G. Aggelis and S. Papanikolaou, 2014. Oleaginous yeast Cryptococcus curvatus exhibits interplay between biosynthesis of intracellular sugars and lipids. Eur. J. Lipid Sci. Technol. (In Press). 10.1002/ejlt.201400347.
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  6. Sarris, D., L. Matsakas, G. Aggelis, A.A. Koutinas and S. Papanikolaou, 2014. Aerated vs non-aerated conversions of molasses and olive mill wastewaters blends into bioethanol by Saccharomyces cerevisiae under non-aseptic conditions. Ind. Crops Prod., 56: 83-93.
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  7. Moustogianni, A., S. Bellou, I.E. Triantaphyllidou and G. Aggelis, 2014. Alterations in fatty acid composition of Cunninghamella echinulata lipids induced by orange essential oil. Environ. Biotechnol., 10: 1-7.
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  8. Kouvelas, A.V., G. Aggelis, A.A. Alexopoulos and K.C. Angelopoulos, 2014. Nitrogen dynamics during growth of sweet sorghum [Sorghum bicolor (L.) Moench] in response to conventional and organic soil fertility management. Aust. J. Corp Sci., 8: 730-737.
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  9. Diamantopoulou, P., S. Papanikolaou, M. Komaitis, G. Aggelis and A. Philippoussis, 2014. Patterns of major metabolites biosynthesis by different mushroom fungi grown on glucose-based submerged cultures. Bioprocess Biosyst. Eng., 37: 1385-1400.
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  10. Bellou, S., M.N. Baeshen, A.M. Elazzazy, D. Aggeli, F. Sayegh and G. Aggelis, 2014. Microalgal lipids biochemistry and biotechnological perspectives. Biotechnol. Adv., 32: 1476-1493.
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  11. Bellou, S., A. Makri, I.E. Triantaphyllidou, S. Papanikolaou and G. Aggelis, 2014. Morphological and metabolic shifts of Yarrowia lipolytica induced by alteration of the dissolved oxygen concentration in the growth environment. Microbiology, 160: 807-817.
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  12. Bellou, S., A. Makri, D. Sarris, K. Michos and P. Rentoumi et al., 2014. The olive mill wastewater as substrate for single cell oil production by Zygomycetes. J. Biotechnol., 170: 50-59.
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  13. Papanikolaou, S., A. Beopoulos, A. Koletti, F. Thevenieau, A.A. Koutinas, J.M. Nicaud and G. Aggelis, 2013. Importance of the methyl-citrate cycle on glycerol metabolism in the yeast Yarrowia lipolytica. J. Biotechnol., 168: 303-314.
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  14. Diamantopoulou, P., S. Papanikolaou, M. Kapoti, M. Komaitis, G. Aggelis and A. Philippoussis, 2012. Mushroom polysaccharides and lipids synthesized in liquid agitated and static cultures. Part I: Screening various mushroom species. Applied Biochem. Biotechnol., 167: 536-551.
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  15. Diamantopoulou, P., S. Papanikolaou, E. Katsarou, M. Komaitis, G. Aggelis and A. Philippoussis, 2012. Mushroom polysaccharides and lipids synthesized in liquid agitated and static cultures. Part II: Study of Volvariella volvacea. Applied Biochem. Biotechnol., 167: 1890-1906.
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  16. Chatzifragkou, A., G. Aggelis, C. Gardeli, M. Galiotou-panayotou, M. Komaitis and S. Papanikolaou, 2012. Adaptation dynamics of Clostridium butyricum in high 1,3-propanediol content media. Applied Microbiol. Biotechnol., 95: 1541-1552.
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  17. Birkou, M., D. Bokas and G. Aggelis, 2012. Improving fatty acid composition of lipids synthesized by Brachionus plicatilis in large scale experiments. J. Am. Oil Chem. Soc., 89: 2047-2055.
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  18. Bellou, S., A. Moustogianni, A. Makri and G. Aggelis, 2012. Lipids containing polyunsaturated fatty acids synthesized by Zygomycetes grown on glycerol. Applied Biochem. Biotechnol., 166: 146-158.
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  19. Bellou, S. and G. Aggelis, 2012. Biochemical activities in Chlorella sp. and Nannochloropsis salina during lipid and sugar synthesis in a lab-scale open pond simulating reactor. J. Biotechnol., 164: 318-329.
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  20. Papanikolaou, S., A. Dimou, S. Fakas, P. Diamantopoulou, A. Philippoussis, M. Galiotou-Panayotou and G. Aggelis, 2011. Biotechnological conversion of waste cooking olive oil into lipid-rich biomass using Aspergillus and Penicillium strains. J. Applied Mirobiol., 110: 1138-1150.
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  21. Papanikolaou, S. and G. Aggelis, 2011. Lipids of oleaginous yeasts. Part II. Technology and potential applications. Eur. J. Lipid Sci. Technol., 113: 1052-1073.
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  22. Papanikolaou, S. and G. Aggelis, 2011. Lipids of oleaginous yeasts. Part I: Biochemistry of single cell oil production. Eur. J. Lipid Sci. Technol., 113: 1031-1051.
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  23. Makri, A. S. Bellou, M. Birkou, K. Papatrehas and N.P. Dolapsakis et al., 2011. Lipid synthesized by micro-algae grown in laboratory- and industrial-scale bioreactors. Eng. Life Sci., 11: 52-58.
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  24. Kavadia, A., D.V. Vayenas, S. Pavlou and G. Aggelis, 2011. Dynamics of a free-living nitrogen-fixing bacteria population lacking of competitive advantage towards an antagonistic population. Open Environ. Eng. J., 4: 190-198.
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  25. Economou, C.N., I.A. Vasiliadou, G. Aggelis, S. Pavlou and D.V. Vayenas, 2011. Modeling of oleaginous fungal biofilm developed on semi-solid media. Bioresour. Technol., 102: 9697-9704.
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  26. Economou, C.N., G. Aggelis, S. Pavlou and D.V. Vayenas, 2011. Single cell oil production from rice hulls hydrolysate. Bioresour. Technol., 102: 9737-9742.
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  27. Economou, C.N., G. Aggelis, S. Pavlou and D.V. Vayenas, 2011. Modeling of single-cell oil production under nitrogen-limited and substrate inhibition conditions. Biotechnol. Bioeng., 108: 1049-1055.
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  28. Chatzifragkou, A., G. Aggelis, M. Komaitis, A.P. Zeng and S. Papanikolaou, 2011. Impact of anaerobiosis strategy and bioreactor geometry on the biochemical response of Clostridium butyricum VPI 1718 during 1,3-propanediol fermentation. Bioresour. Technol., 102: 10625-10632.
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  29. Chatzifragkou, A., A. Makri, A. Belka, S. Bellou and M. Mavrou et al., 2011. Biotechnological conversions of biodiesel derived waste glycerol by yeast and fungal species. Energy, 36: 1079-1105.
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  30. Papanikolaou, S., P. Diamantopoulou, A. Chatzifragkou, A. Philippoussis and G. Aggelis, 2010. Suitability of low-cost sugars as substrates for lipid production by the fungus Thamnidium elegans. Energy Fuels, 24: 4078-4086.
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  31. Papanikolaou, S. and G. Aggelis, 2010. Yarrowia lipolytica: A model microorganism used for the production of tailor‐made lipids. Eur. J. Lipid Sci. Technol., 112: 639-654.
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  32. Makri, A., S. Fakas and G. Aggelis, 2010. Metabolic activities of biotechnological interest in Yarrowia lipolytica grown on glycerol in repeated batch cultures. Biores. Technol., 101: 2351-2358.
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  33. Fakas, S., I. Kefalogianni, A. Makri, G. Tsoumpeli and G. Rouni et al., 2010. Characterization of olive fruit microflora and its effect on olive oil volatile compounds biogenesis. Eur. J. Lipid Sci. Technol., 112: 1024-1032.
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  34. Economou, C.N., A. Makri, G. Aggelis, S. Pavlou and D.V. Vayenas, 2010. Semi-solid state fermentation of sweet sorghum for the biotechnological production of single cell oil. Biores. Technol., 101: 1385-1388.
    CrossRef  |  PubMed  |  Direct Link  |  
  35. Chtzifragkou, A., S. Fakas, M. Galiotou-Panayotou, M. Komaitis, G. Aggelis and S. Papanikolaou, 2010. Commercial sugars as substrates for lipid accumulation in Cunninghamella echinulata and Mortierella isabellina fungi. Eur. J. Lipid Sci. Technol., 112: 1048-1057.
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  36. Papanikolaou, S., A. Chatzifragkou, S. Fakas, M. Galiotou-Panayotou, M. Komaitis, J.M. Nicaud and G. Aggelis, 2009. Biosynthesis of lipids and organic acids by Yarrowia lipolytica strains cultivated on glucose. Eur. J. Lipid Sci., 111: 1221-1232.
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  37. Papanikolaou, S. and G. Aggelis, 2009. Biotechnological valorization of biodiesel derived glycerol waste through production of single cell oil and citric acid by Yarrowia lipolytica. Lipid Technol., 21: 83-87.
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  38. Fakas, S., S. Papanikolaou, M. Galiotou-Panayotou, M. Komaitis and G. Aggelis, 2009. Biochemistry and Biotechnology of Single Cell Oil. In: New Horizons in Biotechnology, Pandey, A. and C. Larroche (Eds.). Asiatech Publishers, Inc., ND.
  39. Fakas, S., S. Papanikolaou, A. Batsos, M. Galiotou-Panayotou, A. Mallouchos and G. Aggelis, 2009. Evaluating renewable carbon sources as substrates for single cell oil production by Cunninghamella echinulata and Mortierella isabellina. Biomass Bioenergy, 33: 573-580.
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  40. Fakas, S., S. Bellou, A. Makri and G. Aggelis, 2009. Single Cell Oil and Gamma-Linolenic Acid Production by Thamnidium Elegans Grown on Raw Glycerol. In: Microbial Conversions of Raw Glycerol, Aggelis, G. (Ed.). Nova Science Publishers, Inc., ΝΥ.
  41. Fakas, S., A. Makri, S. Bellou and G. Aggelis, 2009. Pathways to Aerobic Glycerol Catabolism and their Regulation. In: Microbial Conversions of Raw Glycerol, Aggelis, G. (Ed.). Nova Science Publishers, Inc., Νew Υork.
  42. Fakas, S., A. Makri, M. Mavromati, M. Tselepi and G. Aggelis, 2009. Fatty acid composition in lipid fractions lengthwise the mycelium of Mortierella isabellina and lipid production by solid state fermentation. Biores. Technol., 100: 6118-6120.
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  43. Aggelis, G., 2009. Microbial Conversions of Raw Glycerol. Nova Science Publishers, Inc., Νew Υork.
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  44. Tsagou, V. and G. Aggelis, 2008. Growth and Nitrogen Fixation of Azospirillum Lipoferum Cultivated on Olive Oil Mill Wastewater. In: Nitrogen Fixation Research Progress, Couto, G.N. (Ed.). Nova Science Publishers Inc., Νew Υork.
  45. Papanikolaou, S., S. Fakas, M. Fick, I. Chevalot and M. Galiotou-Panayotou et al., 2008. Biotechnological valorisation of raw glycerol discharged after bio-diesel (fatty acid methyl esters) manufacturing process: Production of 1,3-propanediol, citric acid and single cell oil. Biomass Bioenergy, 32: 60-71.
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  46. Papanikolaou, S., M. Galiotou-Panayotou, S. Fakas, M. Komaitis and G. Aggelis, 2008. Citric acid production by Yarrowia lipolytica cultivated on olive-mill wastewater-based media. Biores. Technol., 99: 2419-2428.
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  47. Kavadia, A., D.V. Vayenas, S. Pavlou and G. Aggelis, 2008. Dynamics of free-living nitrogen-fixing bacterial populations and nitrogen fixation in a two-prey-one-predator system. Ecol. Mod., 218: 323-338.
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  48. Fakas, S., S. Papanikolaou, M. Galiotou-Panayotou, M. Komaitis and G. Aggelis, 2008. Organic nitrogen of tomato waste hydrolysate enhances glucose uptake and lipid accumulation in Cunninghamella echinulata. J. Applied Microbiol., 105: 1062-1070.
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  49. Fakas, S., M. Certik, S. Papanikolaou, G. Aggelis, M. Komaitis and M. Galiotou-Panayotou, 2008. Gamma linolenic acid production by Cunninghamella echinulata growing on complex organic nitrogen sources. Biores. Technol., 99: 5986-5990.
    PubMed  |  
  50. Fakas, S., I. Papapostolou, S. Papanikolaou, C.D. Georgiou and G. Aggelis, 2008. Susceptibility to peroxidation of the major mycelial lipids of Cunninghamella echinulata. Eur. J. Lipid Sci. Technol., 110: 1062-1067.
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  51. Papanikolaou, S., M. Galiotou-Panayotou, S. Fakas, M. Komaitis and G. Aggelis, 2007. Lipid production by oleaginous Mucorales cultivated on renewable carbon sources. Eur. J. Lipid Sci. Technol., 109: 1060-1070.
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  52. Papanikolaou, S., I. Chevalot, M. Galiotou-Panayotou, M. Komaitis, I. Marc and G. Aggelis, 2007. Industrial derivative of tallow: A promising renewable substrate for microbial lipid, single-cell protein and lipase production by Yarrowia lipolytica. Electron. J. Biotechnol., 10: 425-435.
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  53. Kavadia, A., D.V. Vayenas, S. Pavlou and G. Aggelis, 2007. Dynamics of free-living nitrogen-fixing bacterial populations in antagonistic conditions. Ecol. Mod., 200: 243-253.
    CrossRef  |  Direct Link  |  
  54. Fakas, S., M. Galiotou-Panayotou, S. Papanikolaou, M. Komaitis and G. Agglis, 2007. Compositional shifts in lipid fractions during lipid turnover in Cunninghamella echinulata. Enz. Microb. Technol., 40: 1321-1327.
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  55. Aktypis, A., M. Tychowski, G. Kalantzopoulos and G. Aggelis, 2007. Studies on bacteriocin (thermophilin T) production by Streptococcus thermophilus ACA-DC 0040 in batch and fed-batch fermentation modes. Antonie Leeuwenhoek J. Microbiol., 92: 207-220.
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  56. Aggelis, G., 2007. Microbiology and Microbial Technology. A. Stamoulis Publishers, Athens, Greece.
  57. Tsagou, V. and G. Aggelis, 2006. Growth dynamics of Azospirillum lipoferum at steady and transitory states in the presence of NH4+. J. Applied Microbiol., 100: 286-295.
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  58. Papanikolaou, S., M. Galiotou-Panayotou, I. Chevalot, M. Komaitis, I. Marc and G. Aggelis, 2006. Influence of glucose and saturated free-fatty acid mixtures on citric acid and lipid production by Yarrowia lipolytica. Curr. Microbiol., 52: 134-142.
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  59. Fakas, S., S. Papanikolaou, M. Galiotou-Panayotou, M. Komitis and G. Aggelis, 2006. Lipids of Cunninghamella echinulata with emphasis to γ-linolenic acid distribution among lipid classes. Applied Microbiol. Biotechnol., 73: 676-683.
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  60. Vayenas, D.V., G. Aggelis, V. Tsagou and S. Pavlou, 2005. Dynamics of a two-prey-one-predator system with predator switching regulated by a catabolic repression control-like mode. Ecol. Model., 186: 345-357.
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  61. Aggelis, G., D.V. Vayenas, V. Tsagou and S. Pavlou, 2005. Prey-predator dynamics with predator switching regulated by a catabolic repression control mode. Ecol. Model., 183: 451-462.
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  62. TSAGOU, V., A. Lianou, D. Lazarakis, N. Emmanouel and G. Aggelis, 2004. Newly isolated bacterial strains belonging to Bacillaceae (Bacillus sp.) and Micrococcaceae accelerate death of Varroa destructor (V. jacobsoni) in laboratory assays. Biotechnol. Lett., 26: 529-532.
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  63. Papanikolaou, S., S. Sarantou, M. Komaitis and G. Aggelis, 2004. Repression of reserve lipid turnover in Cunninghamella echinulata and Mortierella isabellina cultivated in multiple-limited media. J. Applied Microbiol., 97: 867-875.
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  64. Papanikolaou, S., M. Komaitis and G. Aggelis, 2004. Single cell oil (SCO) production by Mortierella isabellina grown on high sugar content media. Bioresour. Technol., 95: 287-291.
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  65. Papanikolaou, S., M. Fick and G. Aggelis, 2004. The effect of raw glycerol concentration on the production of 1,3-propanediol by Clostridium butyricum. J. Chem. Technol. Biotechnol., 79: 1189-1196.
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  66. Tsagou, V., I. Kefalogianni, K. Sini and G. Aggelis, 2003. Metabolic activities in Azospirillum lipoferum in the presence of NH+. Applied Microbiol. Biotechnol., 62: 574-578.
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  67. Papanikolaou, S., L. Muniglia, I. Chevalot, G. Aggelis and I. Marc, 2003. Accumulation of a cocoa-butter-like lipid by Yarrowia lipolytica growing on agro-industrial residues. Curr. Microbiol., 46: 124-130.
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  68. Papanikolaou, S. and G. Aggelis, 2003. Selective uptake of fatty acids by the yeast Yarrowia lipolytica. Eur. J. Lipid Sci. Technol., 105: 651-655.
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  69. Papanikolaou, S. and G. Aggelis, 2003. Modelling lipid accumulation and degradation in Yarrowia lipolytica cultivated on industrial fats. Curr. Microbiol., 46: 398-402.
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  70. Papanikolaou, S. and G. Aggelis, 2003. Modelling aspects of the biotechnological valorization of raw glycerol: Production of citric acid by Yarrowia lipolytica and 1,3 propanediol by Clostridium butyricum. J. Chem. Technol. Biotechnol., 78: 542-547.
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  71. Aggelis, G., D. Iconomou, M. Christou, D. Bokas and S. Kotzailias et al., 2003. Phenolic removal in a model olive oil mill wastewater using Pleurotus ostreatus in bioreactor cultures and biological evaluation of the process. Water Res., 37: 3897-3904.
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  72. Tsioulpas, A., D. Dimou, D. Ikonomou and G. Aggelis, 2002. Phenolic removal in olive oil mill wastewater by strains of Pleurotus spp. in respect to their phenol oxidase (laccase) activity. Bioresour. Technol., 84: 251-257.
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  73. Papanikolaou, S., L. Muniglia, I. Chevalot, G. Aggelis and I. Marc, 2002. Yarrowia lipolytica as a potential producer of citric acid from raw glycerol. J. Appl. Microbiol., 92: 737-744.
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  74. Papanikolaou, S., I. Chevalot, M. Komaitis, I. Marc and G. Aggelis, 2002. Single Cell Oil (S.C.O.) production by Yarrowia lipolytica growing on an industrial derivative of animal fat. Applied Microbiol. Biotechnol., 58: 308-312.
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  75. Papanikolaou, S. and G. Aggelis, 2002. Lipid production by Yarrowia lipolytica growing on industrial glycerol in a single-stage continuous culture. Bioresour. Technol., 82: 43-49.
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  76. Mallouchos, A., P. Reppa, G. Aggelis, A.A. Koutinas, M. Kanellaki and M. Komaitis, 2002. Grape skins as a natural support for yeast immobilization. Biotechnol. Lett., 23: 1331-1335.
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  77. Kefalogianni, I. and G. Aggelis, 2002. Modelling growth and biochemical activities of Azospirillum spp. Applied Microbiol. Biotechnol., 58: 352-357.
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  78. Gema, H., A. Kavadia, D. Dimou, V. Tsagou, M. Komaitis and G. Aggelis, 2002. Production of γ-linolenic acid by Cunninghamella echinulata cultivated on glucose and orange peels. Applied Microbiol. Biotechnol., 58: 303-307.
    Direct Link  |  
  79. Dimou, D., A. Georgala, M. Komaitis and G. Aggelis, 2002. Mycelial fatty acid composition of Pleurotus spp. and application in the intrageneric differentiation. Mycol. Res., 106: 925-929.
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  80. Papanikolaou, S., I. Chevalot, M. Komaitis, G. Aggelis and I. Marc, 2001. Kinetic profile of the cellular lipid composition in an oleaginous Yarrowia lipolytica capable of producing a cocoa-butter substitute from industrial fats. Antonie van Leeuwenhoek, 80: 215-224.
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  81. Kavadia, A., M. Komaitis, I. Chavelot, F. Blanchard, I. Marc and G. Aggelis, 2001. Lipid and γ-linolenic acid accumulation in strains of Zygomycetes growing on glucose. J. Am. Oil Chem. Soc., 78: 341-346.
    Direct Link  |  
  82. Karanika, M. S., M. Komaitis and G. Aggelis, 2001. Effect of aqueous extracts of some plants of Lamiaceae family on the growth of Yarrowia lipolytica. Int. J. Food Microbiol., 64: 175-181.
    PubMed  |