Dr. Russo  Emilio

Dr. Russo Emilio

Lecturer
University of Catanzaro, Italy


Highest Degree
Ph.D. in Pharmacological Sciences and Respiratory Physiopathology from Seconda Universita of Naples, Italy

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Area of Interest:

Pharmacology and Toxicology
100%
Pharmacology
62%
Physiopathology of Epilepsies
90%
Epileptogenesis
75%
Drug Delivery
55%

Education

2006

Ph.D.

Seconda Universita of Naples, Italy

Pharmacological Sciences and Respiratory Physiopathology

Selected Publications

  1. Ventrice, P., D. Ventrice, E. Russo and G. de Sarro, 2013. Phthalates: European regulation, chemistry, pharmacokinetic and related toxicity. Environ. Toxicol. Pharmacol., 36: 88-96.
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  2. Siniscalchi, A., L. Gallelli, S. Loizzo, A. Tiziana, E. Russo and G. de Sarro, 2013. Sodium valproate induced tremor in a patient with epilepsy and down's syndrome. Curr. Drug Saf., 8: 69-71.
    PubMed  |  Direct Link  |  

  3. Siniscalchi, A., L. Gallelli, E. Russo and G. de Sarro, 2013. A review on antiepileptic drugs-dependent fatigue: Pathophysiological mechanisms and incidence. Eur. J. Pharmacol., 718: 10-16.
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  4. Sammarco, G., F. Ferrari, A. Carpino, E. Russo, G. Vescio, M. Ammendola and R. Sacco, 2013. PPH vs Milligan-Morgan: Early and late complications in the treatment of haemorrhoidal disease with circumferential prolapse. Ann. Ital. Chir. .
    PubMed  |  Direct Link  |  

  5. Russo, E., S. Chimirri, R. Aiello, S. de Fazio and A. Leo et al., 2013. Lamotrigine positively affects the development of psychiatric comorbidity in epileptic animals, while psychiatric comorbidity aggravates seizures. Epilepsy Behav., 28: 232-240.
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  6. Russo, E., R. Citraro, A. Davoli, L. Gallelli, E.D. di Paola and G. de Sarro, 2013. Ameliorating effects of aripiprazole on cognitive functions and depressive-like behavior in a genetic rat model of absence epilepsy and mild-depression comorbidity. Neuropharmacology, 64: 371-379.
    CrossRef  |  PubMed  |  Direct Link  |  

  7. Russo, E., F. Scicchitano, B.J. Whalley, C. Mazzitello and M. Ciriaco et al., 2013. Hypericum perforatum: Pharmacokinetic, mechanism of action, tolerability and clinical drug-drug interactions. Phytother. Res. 10.1002/ptr.5050.
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  8. Russo, E., E.D. Paola, P. Gareri, A. Siniscalchi and A. Labate et al., 2013. Pharmacodynamic potentiation of antiepileptic drugs' effects by some HMG-CoA reductase inhibitors against audiogenic seizures in DBA/2 mice. Pharmacol. Res., 70: 1-12.
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  9. Rispoli ,V., S. Ragusa, R. Nistico, R. Marra, E. Russo, A. Leo, V. Felicita, D. Rotiroti, 2013. Huperzine a restores cortico-hippocampal functional connectivity after bilateral AMPA lesion of the nucleus basalis of meynert. J. Alzheimers Dis., 35: 833-846.
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  10. Ranieri, G., M. Mammi, E.D. di Paola, E. Russo and L. Gallelli et al., 2013. Pazopanib a tyrosine kinase inhibitor with strong anti-angiogenetic activity: A new treatment for metastatic soft tissue sarcoma. Crit. Rev. Oncol. Hematol. 10.1016/j.critrevonc.2013.08.012.
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  11. Patane, M., M. Ciriaco, S. Chimirri, F. Ursini and S. Naty et al., 2013. Interactions among low dose of methotrexate and drugs used in the treatment of rheumatoid arthritis. Adv. Pharmacol. Sci. 10.1155/2013/313858.
    CrossRef  |  PubMed  |  Direct Link  |  

  12. Leporini, C., A. Rende, A. Sorrentino, E. Rizzica, E. Russo, L. Gallelli and G. de Sarro, 2013. Efficacy and safety of off-label use of fondaparinux in the management of heparin-induced thrombocytopenia with thrombosis in an elderly woman. J. Clin. Pharmacol., 53: 999-1002.
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  13. De Vuono, A., F. Scicchitano, C. Palleria, E. Russo, G. de Sarro and L. Gallelli, 2013. Lack of efficacy during the switch from brand to generic allopurinol. J. Forensic Legal Med., 20: 540-542.
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  14. Citraro, R., E. Russo, R. Ngomba, F. Nicoletti, F. Scicchitano, B. Whalley, A. Calignano and G. de Sarro, 2013. CB1 agonists, locally applied to the cortico-thalamic circuit of rats with genetic absence epilepsy, reduce epileptic manifestations. Epilepsy Res., 106: 74-82.
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  15. Citraro, R., E. Russo, F. Scicchitano, C.M. van Rijn and D. Cosco et al., 2013. Antiepileptic action of N-palmitoylethanolamine through CB1 and PPAR-α receptor activation in a genetic model of absence epilepsy. Neuropharmacology, 69: 115-126.
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  16. Ammendola, M., R. Sacco, G. Donato, V. Zuccala and E. Russo et al., 2013. Mast cell positivity to tryptase correlates with metastatic lymph nodes in gastrointestinal cancer patients treated surgically. Oncology, 85: 111-116.
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  17. Scicchitano, F., C. Giofre, C. Palleria, C. Mazzitello and M. Ciriaco et al., 2012. Pharmacovigilance and drug safety 2011 in Calabria (Italy): Adverse events analysis. J. Res. Med. Sci., 17: 872-875.
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  18. Russo, E., R. Gitto, R. Citraro, A. Chimirri and G. de Sarro, 2012. New AMPA antagonists in epilepsy. Expert Opin. Investigat. Drugs., 21: 1371-1389.
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  19. Russo, E., R. Citraro, G. Donato, C. Camastra and R. Iuliano et al., 2012. mTOR inhibition modulates epileptogenesis, seizures and depressive behavior in a genetic rat model of absence epilepsy. Neuropharmacology, 69: 25-36.
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  20. Russo, E., R. Citraro, A. Constanti and G. de Sarro, 2012. The mTOR signaling pathway in the brain: Focus on epilepsy and epileptogenesis. Mol. Neurobiol., 46: 662-681.
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  21. Russo, E., F. Scicchitano, R. Citraro, R. Aiello and C. Camastra et al., 2012. Protective activity a-lactoalbumin (ALAC), a whey protein rich in tryptophan, in rodent models epileptogenesis. Neuroscience. .

  22. Perrotta, I., L. Bruno, L. Maltese, E. Russo, A. Donato and G. Donato, 2012. Immunohistochemical analysis of the ubiquitin-conjugating enzyme UbcH10 in lung cancer: A useful tool for diagnosis and therapy. J. Histochem. Cytochem., 60: 359-365.
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  23. Gitto, R., L. de Luca, S. Ferro, M.R. Buemi, E. Russo and G. de Sarro et al., 2012. Synthesis and biological characterization of 3-substituted 1H-indoles as ligands of GluN2B-containing N-methyl-D-aspartate receptors. Part 2. J. Med. Chem., 55: 10532-10539.
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  24. De Sarro, G., E.D. di Paola, S. Gratteri, P. Gareri and V. Rispoli et al., 2012. Fosinopril and zofenopril, two angiotensin-converting enzyme (ACE) inhibitors, potentiate the anticonvulsant activity of antiepileptic drugs against audiogenic seizures in DBA/2 mice. Pharmacol. Res., 65: 285-296.
    CrossRef  |  PubMed  |  Direct Link  |  

  25. De Fazio, S., E. Russo, M. Ammendola, E.D. di Paola and G. de Sarro, 2012. Efficacy and safety of bevacizumab in glioblastomas. Curr. Med. Chem., 19: 972-981.
    PubMed  |  Direct Link  |  

  26. Ammendola, M., V. Zuccala, R. Patruno, E. Russo and M. Luposella et al., 2012. Tryptase-positive mast cells and angiogenesis in keloids: A new possible post-surgical target for prevention. Updates Surg., 65: 53-57.
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  27. Russo, E., R. Citraro, F. Scicchitano, S. De Fazio and I. Perrota et al., 2011. Effects of early long-term treatment with antiepileptic drugs on development of seizures and depressive-like behavior in a rat genetic absence epilepsy model. Epilepsia, 52: 1341-1350.
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  28. Russo, E., R. Citraro, F. Scicchitano, A. Urzino, R. Marra, V. Rispoli and G. de Sarro, 2011. Vigabatrin has antiepileptogenic and antidepressant effects in an animal model of epilepsy and depression comorbidity. Behav. Brain Res., 225: 373-376.
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  29. Perrotta, I., V. Carito, E. Russo, S. Tripepi, S. Aquila and G. Donato, 2011. Macrophage autophagy and oxidative stress: An ultrastructural and immunoelectron microscopical study. Oxid. Med. Cell. Longev. 10.1155/2011/282739.
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  30. Perrotta, I., E. Russo, C. Camastra, G. Filice and G. di Mizio et al., 2011. New evidence for a critical role of elastin in calcification of native heart valves: Immunohistochemical and ultrastructural study with literature review. Histopathology, 59: 504-513.
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  31. Gitto, R., L. de Luca, S. Ferro, M. Buemi and E. Russo et al., 2011. Synthesis and biological characterization of 3-substituted-1H-indoles as ligands of GluN2Bcontaining N-methyl-D-aspartate receptors. J. Med. Chem., 54: 8702-8706.

  32. Citraro, R., F. Scicchitano, S. De Fazio, R. Raggio and P. Mainardi et al., 2011. Preclinical activity profile of α-lactoalbumin, a whey protein rich in tryptophan, in rodent models of seizures and epilepsy. Epilepsy Res., 95: 60-69.

  33. Sasso, O., G. la Rana, S. Vitiello, R. Russo and G. D'Agostino et al., 2010. Palmitoylethanolamide modulates pentobarbital-evoked hypnotic effect in mice: Involvement of allopregnanolone biosynthesis. Eur. Neuropsychopharmacol., 20: 195-206.
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  34. Russo, E., R. Citraro, F. Scicchitano, S. de Fazio, E.D. di Paola, A. Constanti and G. de Sarro, 2010. Comparison of the antiepileptogenic effects of an early long-term treatment with ethosuximide or levetiracetam in a genetic animal model of absence epilepsy. Epilepsia, 51: 1560-1569.
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  35. Perrotta, I., M.G. Cristofaro, M. Amantea, E. Russo and S. De Fazio et al., 2010. Jaw osteonecrosis in patients treated with bisphosphonates: An ultrastructural study. Ultrastruct. Pathol., 34: 207-213.
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  36. Gitto, R., L. De Luca, S. Ferro, S. Agnello, E. Russo, G. De Sarro and A. Chimirri, 2010. Synthesis and structure-active relationship of 1-aryl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline anticonvulsants. Chem. Pharm. Bull., 58: 1602-1605.
    PubMed  |  Direct Link  |  

  37. Rimoli, M.G., E. Russo, M. Cataldi, R. Citraro and P. Ambrosino et al., 2009. T-type channel blocking properties and antiabsence activity of two imidazo[1,2-b]pyridazine derivatives structurally related to indomethacin. Neuropharmacology, 56: 637-646.
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  38. Gitto, R., S. Ferro, S. Agnello, L. De Luca and G. De Sarro et al., 2009. Synthesis and evaluation of pharmacological profile of 1-aryl-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-sulfonamides. Bioorg. Med. Chem., 17: 3659-3664.
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  39. Donato, G., O. Galasso, P. Valentino, F. Conforti and V. Zuccala et al., 2009. Pathological findings in subsynovial connective tissue in idiopathic carpal tunnel syndrome. Clin. Neuropathol., 28: 129-135.
    PubMed  |  Direct Link  |  

  40. Donato, G., F. Conforti, V. Zuccala, E. Russo, L. Maltese, I. Perrotta and A. Amorosi, 2009. Expression of tenascin-c and CD44 receptors in cardiac myxomas. Cardiovasc Pathol., 18: 173-177.
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  41. D'Alimonte, I., M. D'Auro, R. Citraro, F. Biagioni and S. Jiang et al., 2009. Altered distribution and function of A2A adenosine receptors in the brain of WAG/Rij rats with genetic absence epilepsy, before and after appearance of the disease. Eur. J. Neurosci., 30: 1023-1035.
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  42. Russo, E., R. Citraro, S.D. Fazio, R. Marra and R. Gitto et al., 2008. Enhancement of anti-absence effects of ethosuximide by low doses of a noncompetitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist in a genetic animal model of absence epilepsy. Epilepsy Behav., 13: 295-299.
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  43. Russo, E., R. Citraro, S. De Fazio, G. Torcasio, G. De Sarro and E.D. Di Paola, 2008. Effects of ethanol on the development of genetically determined epilepsies in rats. Int. J. Dev. Neurosci., 26: 739-744.
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  44. Pisu, M.G., M.C. Mostallino, R. Dore, M.L. Mura and E. Maciocco et al., 2008. Neuroactive steroids and GABAA receptor plasticity in the brain of the WAG/Rij rat, a model of absence epilepsy. J. Neurochem., 106: 2502-2514.
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  45. Gitto, R., L. De Luca, S. Ferro, F. Occhiuto and S. Samperi et al., 2008. Computational studies to discover a new NR2B/NMDA receptor antagonist and evaluation of pharmacological profile. Chem. Med. Chem., 3: 1539-1548.
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  46. Gareri, P., P. De Fazio, E. Russo, N. Marigliano, S. De Fazio and G. De Sarro, 2008. The safety of clozapine in the elderly. Expert Opin. Drug Safety, 7: 525-538.
    CrossRef  |  PubMed  |  Direct Link  |  

  47. Russo, E., S. De Fazio, P. De Fazio, A. Amorosi, I. Perrotta, G. De Sarro and G. Donato, 2007. Apomorphine-induced neurodegeneration in Mongolian gerbil hippocampus. Schizophrenia Res., 95: 223-227.
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  48. Gitto, R., R. Ficarra, R. Stancanelli, M. Guardo and L. De Luca et al., 2007. Synthesis, resolution, stereochemistry and molecular modelling of (R)- and (S)-2-acetyl-1-(40-chlorophenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline AMPAR antagonists. Bioorg. Med. Chem., 15: 5417-5423.

  49. Gitto, R., R. Caruso, B. Pagano, L. De Luca and R. Citraro et al., 2006. Novel potent anticonvulsant agent containing a tetrahydroisoquinoline skeleton. J. Med. Chem., 49: 5618-5622.
    CrossRef  |  PubMed  |  Direct Link  |  

  50. De Luca, G., R.M. Di Giorgio, S. Macaione, P.R. Calpona and E.D. Di Paola et al., 2006. Amino acid levels in some brain areas of inducible nitric oxide synthase knock out mouse (Inos-/-) before and after pentylenetetrazole kindling. Pharmacol. Biochem. Behav., 85: 804-812.
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  51. Citraro, R., E. Russo, S. Gratteri, E.D. Di Paola and G.F. Ibbadu et al., 2006. Effects of non-competitive AMPA receptor antagonists injected into some brain areas of WAG/Rij rats, an animal model of generalized absence epilepsy. Neuropharmacology, 51: 1058-1067.
    CrossRef  |  PubMed  |  Direct Link  |  

  52. Citraro, R., E. Russo, E.D. di Paola, G.F. Ibbadu, R. Marra, S. Gratteri and G. De Sarro, 2006. Effects of some neurosteroids injected into some brain areas of WAG/Rij rats, an animal model of generalized absence epilepsy. Neuropharmacology, 50: 1059-1071.
    CrossRef  |  PubMed  |  Direct Link  |  

  53. Gareri, P., L. Gallelli, G.F. Ibbadu, R. Lacava, E. Russo and G. De Sarro, 2005. Melaena following use of the cholinesterase inhibitor Rivastigmine. Clin. Drug Invest., 25: 215-217.
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  54. Gareri, P., D. Condorelli, N. Belluardo, R. Citraro and V. Barresi et al., 2005. Antiabsence effects of carbenoxolone in two genetic animal models of absence epilepsy (WAG/Rij rats and lh/lh mice). Neuropharmacology, 49: 551-563.
    CrossRef  |  PubMed  |  Direct Link  |  

  55. De Sarro, G., R. Gitto, E. Russo, G.F. Ibbadu, M.L. Barreca, L. De Luca and A. Chimirri, 2005. AMPA receptor antagonists as potential anticonvulsant drugs. Curr. Top. Med. Chem., 5: 31-42.
    PubMed  |  Direct Link  |  

  56. De Luca, G., R.M. Di Giorgio, S. Macaione, P.R. Calpona and S. Costantino et al., 2005. Amino Acid levels in some lethargic mouse brain areas before and after pentylenetetrazole kindling. Pharmacol. Biochem. Behav., 81: 47-53.
    CrossRef  |  PubMed  |  Direct Link  |  

  57. Siniscalchi, A., F. Mancuso, E. Russo, G.F. Ibbadu and G. De Sarro, 2004. Spinal myoclonus responsive to topiramate. Mov. Disord., 19: 1380-1381.
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  58. Russo, E., A. Constanti, G. Ferreri, R. Citraro and G. De Sarro, 2004. Nifedipine affects the anticonvulsant activity of topiramate in various animal models of epilepsy. Neuropharmacology, 46: 865-878.
    CrossRef  |  PubMed  |  Direct Link  |  

  59. Russo, E. and A. Constanti, 2004. Topiramate hyperpolarizes and modulates the slow post-stimulus AHP of rat olfactory cortical neurones In vitro. Br. J. Pharmacol., 141: 285-301.

  60. Quartarone, S., R. Caruso, V. Orlando, E. Russo, G. De Sarro and A. Chimirri, 2004. Synthesis and anticonvulsant activity of N-3 substituted 2,3-benzodiazepines. Il Farmaco, 59: 353-358.
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  61. Gitto, R., R. Caruso, V. Orlando, S. Quartarone and M.L. Barreca et al., 2004. Synthesis and anticonvulsant properties of tetrahydroisoquinoline derivatives. Il Farmaco, 59: 7-12.
    CrossRef  |  PubMed  |  Direct Link  |  

  62. Gitto, R., M.L. Barreca, E. Francica, R. Caruso and L. De Luca et al., 2004. Synthesis and anticonvulsant properties of 1,2,3,4-tetrahydroisoquinolin-1-ones. Arch. Organ. Chem., 2004: 170-180.
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  63. Gareri, P., D. Condorelli, D. Belluardo, E. Russo and A. Loiacono et al., 2004. Anticonvulsant effects of carbenoxolone in genetically epilepsy prone rats (GEPRs). Neuropharmacology, 47: 1205-1216.
    CrossRef  |  PubMed  |  Direct Link  |  

  64. Fischer, W., H. Kittner, R. Regenthal, E. Russo and G. De Sarro, 2004. Effects of piracetam alone and in combination with antiepileptic drugs in rodent seizure models. J. Neural. Transm., 111: 1121-1139.
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  65. Ferreri, G., A. Chimirri, E. Russo, R. Gitto and P. Gareri et al., 2004. Comparative anticonvulsant activity of N-acetyl-1-aryl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline derivatives in rodents. Pharmacol. Biochem. Behav., 77: 85-94.
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  66. De Sarro, G., G.F. Ibbadu, R. Marra, D. Rotiroti, A. Loiacono, E.D. Di Paola and E. Russo, 2004. Seizure susceptibility to various convulsant stimuli in dystrophin-deficient mdx mice. Neurosci. Res., 50: 37-44.
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  67. De Sarro, G., E. Russo, G. Ferreri, G. Bruzzese, M.A. Flocco, E.D. Di Paola and A. De Sarro, 2004. Seizure susceptibility to various convulsant stimuli of knockout interleukin 6 mice. Pharmacol. Biochem. Behav., 77: 761-766.
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  68. Gitto, R., V. Orlando, S. Quartarone, G. De Sarro and A. De Sarro et al., 2003. Synthesis and evaluation of pharmacological properties of novel annelated 2,3-benzodiazepine derivatives. J. Med. Chem., 46: 3758-3761.
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  69. Gitto, R., M.L. Barreca, L. De Luca, G. De Sarro and G. Ferreri et al., 2003. Discovery of a novel and highly potent noncompetitive AMPA receptor antagonist. J. Med. Chem., 46: 197-200.
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  70. De Sarro, G., G. Ferreri, P. Gareri, E. Russo, A. De Sarro, R. Gitto and A. Chimirri, 2003. Comparative anticonvulsant activity of some 2,3-benzodiazepine derivatives in rodents. Pharmacol. Biochem. Behav., 74: 595-602.
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  71. Conti, P., M. De Amici, S.J. di Ventimiglia, T.B. Stensbol and U. Madsen et al., 2003. Synthesis and anticonvulsant activity of novel bicyclic acidic amino acids. J. Med. Chem., 46: 3102-3108.
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