Hi, I am Emanuela Masini, My LiveDNA is 39.5998
 
   
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Dr. Emanuela Masini
 
Highest Degree: M.D. in Medicine from University of Florence, Italy
 
Institute: University of Florence, Italy
 
Area of Interest: Biomedical Sciences
  •   Autacoids
  •   Cardiac Ischaemia and Reperfusion
  •   Cannabinoids
  •   Relaxin and Bioheparins
 
URL: http://livedna.org/39.5998
 
My SELECTED Publications
1:   Bani, D., E. Masini, M.G. Bello, M. Bigazzi and T.B. Sacchi, 1995. Relaxin activates the L-arginine-nitric oxide pathway in human breast cancer cells. Cancer Res., 55: 5272-5275.
PubMed  |  Direct Link  |  
2:   Bani, D., E. Masini, M.G. Bello, M. Bigazzi and T.B. Sacchi, 1998. Relaxin protects against myocardial injury caused by ischemia and reperfusion in rat heart. Am. J. Pathol., 152: 1367-1376.
PubMed  |  Direct Link  |  
3:   Bani, D., L. Ballati, E. Masini, M. Bigazzi and T.B. Sacchi, 1997. Relaxin counteracts asthma-like reaction induced by inhaled antigen in sensitized guinea pigs. Endocrinology, 138: 1909-1915.
CrossRef  |  PubMed  |  Direct Link  |  
4:   Bani, D., L. Giannini, A. Ciampa, E. Masini and Y. Suzuki et al., 2006. Epigallocatechin-3-gallate reduces allergen-induced asthma-like reaction in sensitized guinea pigs. J. Pharmacol. Exp. Therap., 317: 1002-1011.
CrossRef  |  
5:   Bani, D., M. Bigazzi, E. Masini, G. Bani and T.B. Sacchi, 1995. Relaxin depresses platelet aggregation: in vitro studies on isolated human and rabbit platelets. Lab. Invest., 73: 709-716.
PubMed  |  Direct Link  |  
6:   Bani, D., P. Failli, M.G. Bello, C. Thiemermann, T.B. Sacchi, M. Bigazzi and E. Masini, 1998. Relaxin activates the L-arginine-nitric oxide pathway in vascular smooth muscle cells in culture. Hypertension, 31: 1240-1247.
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7:   Bani, D., P.F. Mannaioni and E. Masini, 2006. Cardiac anaphylaxis: Pathophysiology and therapeutic perspectives. Curr. Allergy Asthma Rep., 6: 14-19.
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8:   Bani, D., R. Baronti, A. Vannacci, M. Bigazzi, T. Bani-Sacchi, P.F. Mannaioni and E. Masini, 2002. Inhibitory effects of relaxin on human basophils activated by stimulation of the FC receptor. The role of nitric oxide. Int. Immunopharmacol., 2: 1195-1204.
9:   Bani, D., S. Nistri, L. Cinci, L. Giannini and M. Princivalle et al., 2007. A novel, simple bioactivity assay for relaxin based on inhibition of platelet aggregation. Regulatory Peptides, 144: 10-16.
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10:   Bani-Sacchi, T., M. Barattini, S. Bianchi, P. Blandina and S. Brunelleschi et al., 1986. The release of histamine by parasympathetic stimulation in guinea-pig auricle and rat ileum. J. Physiol., 371: 29-43.
PubMed  |  
11:   Bani-Sacchi, T., M. Bigazzi, D. Bani, P.F. Mannaioni and E. Masini, 1995. Relaxin-induced increased coronary flow through stimulation of nitric oxide production. Br. J. Pharmacol., 116: 1589-1594.
PubMed  |  Direct Link  |  
12:   Baronti, R., E. Masini, L. Bacciottini and P.F. Mannaioni, 2002. Differential effects of amphotericin B and liposomal amphotericin B on inflammatory cells in vitro. Inflamm. Res., 51: 259-264.
CrossRef  |  
13:   Bechi, P., A. Amorosi, R. Mazzanti, R. Dei, S. Bianchi, L. Mugnai and E. Masini, 1993. Reflux-related gastric mucosal injury is associated with increased mucosal histamine content in humans. Gastroenterology, 104: 1057-1063.
PubMed  |  Direct Link  |  
14:   Bechi, P., P. Romagnoli, P. Panula, R. Dei, S. Bacci, A. Amorosi and E. Masini, 1995. Gastric mucosal histamine storing cells. Evidence for different roles of mast cells and enterochromaffin-like cells in humans. Dig. Dis. Sci., 40: 2207-2213.
PubMed  |  Direct Link  |  
15:   Bechi, P., P. Romagnoli, S. Bacci, R. Dei, A. Amorosi, F. Cianchi and E. Masini, 1996. Helicobacter pylori and duodenal ulcer: Evidence for a histamine pathways-involving link. Am. J. Gastroenterol., 91: 2338-2343.
PubMed  |  Direct Link  |  
16:   Bechi, P., R. Dei, M.G. Di Bello and E. Masini, 1993. Helicobacter pylori potentiates histamine release from serosal rat mast cells In vitro. Dig. Dis. Sci., 38: 944-949.
CrossRef  |  PubMed  |  Direct Link  |  
17:   Bianchi, P., O. Kunduzova, E. Masini, C. Cambon and D. Bani et al., 2005. Oxidative stress by monoamine oxidase mediates receptor-independent cardiomyocyte apoptosis by serotonin and postischemic myocardial injury. Circulation, 112: 3297-3305.
Direct Link  |  
18:   Blandina, P., M. Barattini, R. Fantozzi, E. Masini, S. Brunelleschi and P.F. Mannaioni, 1984. Mediator release from isolated rat ileum in response to field stimulation. Agents Actions, 14: 405-459.
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19:   Blandina, P., R. Fantozzi, P.F. Mannaioni and E. Masini, 1980. Characteristics of histamine release evoked by acetylcholine in isolated rat mast cells. J. Physiol., 301: 281-293.
Direct Link  |  
20:   Blandina, P., S. Brunelleschi, R. Fantozzi, E. Giannella, P.F. Mannaioni and E. Masini, 1987. The antianaphylactic action of histamine H2-receptor agonists in the guinea-pig isolated heart. Br. J. Pharmacol., 90: 459-466.
PubMed  |  
21:   Botti, P., A. Pistelli, F. Gambassi, A.M. Zorn and L. Caramelli et al., 1992. HBV and HCV infection in i.v. drug addicts: Coinfection with HIV. Arch. Virol. Supply, 4: 329-332.
PubMed  |  
22:   Bryant, L., T. Doyle, Z. Chen, S. Cuzzocrea and E. Masini et al., 2009. Spinal ceramide and neuronal apoptosis in morphine antinociceptive tolerance. Neurosci. Lett., 463: 49-53.
CrossRef  |  
23:   Carolina, M., C. Salvatore, M.N. Michael, M. Vincenzo and P. Frank et al., 2007. Therapeutic manipulation of peroxynitrite attenuates the development of opiate-induced antinociceptive tolerance in mice. J. Clin. Invest., 117: 3530-3539.
CrossRef  |  
24:   Carta, F., A. Akdemir, A. Scozzafava, E. Masini and C.T. Supuran, 2013. Xanthates and trithiocarbonates strongly inhibit carbonic anhydrases and show antiglaucoma effects in vivo. J. Med. Chem., 56: 4691-4700.
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25:   Carta, F., M. Aggarwal, A. Maresca, A. Scozzafava, R. McKenna, E. Masini and C.T. Supuran, 2012. Dithiocarbamates strongly inhibit carbonic anhydrases and show antiglaucoma action in vivo. J. Med. Chem., 55: 1721-1730.
CrossRef  |  
26:   Ceccarelli, M., D. Bani, L. Cinci, S. Nistri and C. Uliva et al., 2009. Anti-inflammatory effects of low molecular weight heparin derivative in a rat model of carrageenan-induced pleurisy. J. Cell. Mol. Med., 13: 2704-2712.
CrossRef  |  
27:   Chen, Z., C. Muscoli, T. Doyle, L. Bryant and S. Cuzzocrea et al., 2010. NMDA-receptor activation and nitroxidative regulation of the glutamatergic pathway during nociceptive processing. Pain, 149: 100-106.
CrossRef  |  
28:   Cianchi, F., C. Cortesini, F. Perna, V. Fabbroni and C. Uliva et al., 2006. Prostaglandin E2 correlates with histamine production in human colorectal cancer. Inflammation Res., 55: 81-82.
CrossRef  |  
29:   Cianchi, F., C. Cortesini, L. Magnelli, E. Fanti and L. Papucci et al., 2006. Inhibition of 5-lipoxygenase by MK886 augments the antitumor activity of celecoxib in human colon cancer cells. Mol. Cancer Therap., 5: 2716-2726.
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30:   Cianchi, F., C. Cortesini, N. Schiavone, F. Perna and L. Magnelli et al., 2005. The role of cyclooxygenase-2 in mediating the effects of histamine on cell proliferation and vascular endothelial growth factor production in colorectal cancer. Clin. Cancer Res., 11: 6807-6815.
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31:   Cianchi, F., C. Cortesini, O. Fantappie, L. Messerini and I. Sardi et al., 2004. Cyclooxygenase-2 activation mediates the proangiogenic effect of nitric oxide in colorectal cancer. Clin. Cancer Res., 10: 2694-2704.
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32:   Cianchi, F., C. Cortesini, O. Fantappie, L. Messerini and N. Schiavone et al., 2003. Inducible nitric oxide synthase expression in human colorectal cancer: Correlation with tumor angiogenesis. Am. J. Pathol., 162: 793-801.
CrossRef  |  
33:   Cianchi, F., C. Cortesini, P. Bechi, O. Fantappie and L. Messerini et al., 2001. Up-regulation of cyclooxygenase 2 gene expression correlates with tumor angiogenesis in human colorectal cancer. Gastroenterology, 121: 1339-1347.
CrossRef  |  
34:   Cianchi, F., M.C. Vinci and E. Masini, 2008. Histamine in cancer: The dual faces of the coin. Cancer Biol. Ther., 7: 36-37.
Direct Link  |  
35:   Cianchi, F., M.C. Vinci, C.T. Supuran, B. Peruzzi and P. de Giuli et al., 2010. Selective inhibition of carbonic anhydrase IX decreases cell proliferation and induces ceramide-mediated apoptosis in human cancer cells. J. Pharmacol. Exp. Ther., 334: 710-719.
CrossRef  |  Direct Link  |  
36:   Cianchi, F., S. Cuzzocrea, M.C. Vinci, L. Messerini and C.E. Comin et al., 2010. Heterogeneous expression of cyclooxygenase-2 and inducible nitric oxide synthase within colorectal tumors: Correlation with tumor angiogenesis. Digestive Liver Dis., 42: 20-27.
CrossRef  |  
37:   Cinci, L., E. Masini, A. Bencini, B. Valtancoli, R. Mastroianni, L. Calosi and D. Bani, 2010. Suppression of allergen-induced respiratory dysfunction and airway inflammation in sensitized guinea pigs by MnII(Me2DO2A), a novel superoxide scavenger compound. Free Radical Biol. Med., 48: 1525-1534.
CrossRef  |  
38:   Collino, M., A. Pini, N. Mugelli, R. Mastroianni and D. Bani et al., 2013. Beneficial effect of prolonged heme oxygenase-1 activation in a rat model of chronic heart failure. Dis. Models Mech., 10.1242/dmm.011528.
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39:   Collino, M., S. Castiglia, M. Manoni, L. Salsini, J. Chini, E. Masini and R. Fantozzi, 2009. Effects of a Semi-synthetic N-, O-sulfated glycosaminoglycan K5 polysaccharide derivative in a rat model of cerebral ischaemia/reperfusion injury. Thromb Haemost, 102: 837-845.
40:   Cuzzocrea, S. and E. Masini, 2008. Plant histaminase as an investigational drug in splanchnic artery occlusion and reperfusion. Exp. Opin. Invest. Drugs, 17: 1151-1160.
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41:   Cuzzocrea, S., E. Mazzon, L. Dugo, I. Serraino and R. Di Paola et al., 2002. A role for superoxide in gentamicin-mediated nephropathy in rats. Eur. J. Pharmacol., 450: 67-76.
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42:   Dani, C., E. Masini, G. Bertini, A.M. di Felice and M. Pezzati et al., 2004. Role of heme oxygenase and bilirubin in oxidative stress in preterm infants. Pediatric Res., 56: 873-877.
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43:   De Leval, X., M. Ilies, A. Casini, J.M. Dogne and A. Scozzafava et al., 2004. Carbonic anhydrase inhibitors: Synthesis and topical intraocular pressure lowering effects of fluorine-containing inhibitors devoid of enhanced reactivity. J. Med. Chem., 47: 2796-2804.
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44:   Di Bello, M.G., E. Masini, C. Ioannides, F.J. Ndisang, S. Raspanti, T.B. Sacchi and P.F. Mannaioni, 1998. Histamine release from rat mast cells induced by the metabolic activation of drugs of abuse into free radicals. Inflamm. Res., 47: 122-130.
CrossRef  |  PubMed  |  Direct Link  |  
45:   Di Bello, M.G., F. Gambassi, L. Mugnai, M. Lupini and T.B. Sacchi et al., 1995. Relaxin enhances the coronary outflow in perfused guinea-pig heart: Correlation with histamine and nitric oxide. Inflamm. Res., 44: S102-S103.
CrossRef  |  PubMed  |  Direct Link  |  
46:   Di Bello, M.G., L. Berni, P. Gai, C. Mirabella and J.F. Ndisang et al., 1998. A regulatory role for carbon monoxide in mast cell function. Inflamm. Res., 47: 7-8.
CrossRef  |  PubMed  |  Direct Link  |  
47:   Doyle, T., L. Bryant, I. Batinic-Haberle, J. Little and S. Cuzzocrea et al., 2009. Supraspinal inactivation of mitochondrial superoxide dismutase is a source of peroxynitrite in the development of morphine antinociceptive tolerance. Neuroscience, 164: 702-710.
CrossRef  |  
48:   Emanuela, M., B. Danielle, M. Cosimo, M.M. Alexandru, M.P. Francesco, F. Rodolfo and M. Bruno, 2007. Pea seedling histaminase as a novel therapeutic approach to anaphylactic and inflammatory disorders. Scient. World J., 7: 888-902.
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49:   Fabrizi, F., F. Mincione, T. Somma, G. Scozzafava and F. Galassi et al., 2012. A new approach to antiglaucoma drugs: carbonic anhydrase inhibitors with or without NO donating moieties. Mechanism of action and preliminary pharmacology. J. Enzyme Inhibit. Med. Chem., 27: 138-147.
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50:   Failli, P., A. Vannacci, L.D.C. Mannelli, R. Motterlini and E. Masini, 2012. Relaxant effect of a water soluble carbon Monoxide-releasing molecule (CORM-3) on spontaneously hypertensive rat aortas. Cardiovascular Drugs Therapy, 26: 285-292.
CrossRef  |  
51:   Fantappie, O., E. Masini, I. Sardi, L. Raimondi and D. Bani et al., 2002. The MDR phenotype is associated with the expression of COX‐2 and iNOS in a human hepatocellular carcinoma cell line. Hepatology, 35: 843-852.
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52:   Fantozzi, R., E. Masini, P. Blandina and P.F. Mannaioni, 1979. Cholinergic histamine release: Evidence of muscarinic receptors in rat mast cells. Agents Actions, 9: 57-58.
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53:   Fantozzi, R., E. Masini, P. Blandina, P.F. Mannaioni and T. Bani-Sacchi, 1978. Release of histamine from rat mast cells by acetylcholine. Nature, 273: 473-474.
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54:   Fantozzi, R., E. Masini, P. Blandina, S. Brunelleschi and P.F. Mannaioni, 1983. Receptor modulation of histamine release in isolated purified rat mast cells. Monogr Allergy, 18: 190-192.
55:   Fantozzi, R., E. Masini, P. Blandina, T. Bani-Sacchi, L. Zilletti and P.F. Mannaioni, 1980. Inhibition of cholinergic histamine release in rat mast cells. Agents Actions, 10: 139-140.
PubMed  |  
56:   Fantozzi, R., F. Franconi, P.F. Mannaioni, E. Masini and F. Moroni, 1975. Interaction of histamine H1-and H2-receptor antagonists with histamine uptake and metabolism by guinea-pig isolated atrium and mouse neoplastic mast cells cells in vitro. Br. J. Pharmacol., 53: 569-574.
PubMed  |  
57:   Fantozzi, R., F. Ledda, L. Caramelli, F. Moroni and P. Blandina et al., 1986. Clinical findings and follow-up evaluation of an outbreak of mushroom poisoning-survey of Amanita phalloides poisoning. Klin Wochenschr, 64: 38-43.
PubMed  |  
58:   Fantozzi, R., F. Martinelli, E. Masini, A. Sodi, L. Amaducci and P. Mannaioni, 1981. Use of haemoperfusion with uncoated charcoal in the management of acute intoxications with barbiturate and salicylate. Subst Alcohol. Actions Misuse, 2: 55-62.
PubMed  |  
59:   Fantozzi, R., F. Moroni, E. Masini, P. Blandina and P.F. Mannaioni, 1978. Modulation of the spontaneous histamine release by adrenergic and cholinergic drugs. Agents Actions, 8: 347-358.
PubMed  |  
60:   Fantozzi, R., G. Luciani, E. Masini, P. Blandina and P. Mannaioni, 1980. Clonidine and naloxone-induced opiate withdrawal: A comparison between clonidine and morphine in man. Subst Alcohol. Actions Misuse, 1: 369-373.
PubMed  |  
61:   Fantozzi, R., L. Caramelli, F. Ledda, F. Moroni and E. Masini et al., 1987. Biological markers and therapeutic outcome in alcoholic disease: A twelve-year survey. Klin Wochenschr, 65: 27-33.
PubMed  |  
62:   Fantozzi, R., L. Caramelli, M. Barattini, P. Botti and F. Ledda et al., 1988. Clinical experiences with Ro 15-1788 (Anexate) in benzodiazepine and mixed-drug overdoses. Resuscitation, 16: 79-82.
PubMed  |  
63:   Fantozzi, R., S. Brunelleschi, A. Rubino, S. Tarli, E. Masini and P.F. Mannaioni, 1986. FMLP-activated neutrophils evoke histamine release from mast cells. Agents Actions, 18: 155-158.
PubMed  |  
64:   Fantozzi, R., S. Brunelleschi, G.B. Soldaini, P. Blandina, E. Masini, L. Raimondi and P.F. Mannaioni, 1983. N-Formylmethionyl-leucyl-phenylalanine: Different releasing effects on human neutrophils and rat mast cells. Agents Actions, 13: 218-221.
PubMed  |  
65:   Fantozzi, R., S. Brunelleschi, L. Giuliattini, P. Blandina, E. Masini, G. Cavallo and P.F. Mannaioni, 1985. Mast cell and neutrophil interactions: A role for superoxide anion and histamine. Agents Actions, 16: 260-264.
PubMed  |  
66:   Fantozzi, R., S. Brunelleschi, S. Cambi, P. Blandina, E. Masini and P.F. Mannaioni, 1984. Autacoid andβ-adrenergic agonist modulation of N-formylmethionyl-leucyl-phenylalanine evoked lysosomal enzyme release from human neutrophils. Agents Actions, 14: 441-450.
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67:   Franchi, A., D. Massi, M. Santucci, E. Masini and D.R. Degl'Innocenti et al., 2006. Inducible nitric oxide synthase activity correlates with lymphangiogenesis and vascular endothelial growth factor‐C expression in head and neck squamous cell carcinoma. J. Pathol., 208: 439-445.
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68:   Franchi, A., M. Santucci, E. Masini, I. Sardi, M. Paglierani and O. Gallo, 2002. Expression of matrix metalloproteinase 1, matrix metalloproteinase 2 and matrix metalloproteinase 9 in carcinoma of the head and neck. Cancer, 95: 1902-1910.
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69:   Franchi, A., O. Gallo, M. Paglierani, I. Sardi, L. Magnelli, E. Masini and M. Santucci, 2002. Inducible nitric oxide synthase expression in laryngeal neoplasia: Correlation with angiogenesis. Head Neck, 24: 16-23.
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70:   Galassi, F., A. Sodi, F. Ucci, G. Renieri, B. Pieri and E. Masini, 2000. Ocular haemodynamics and nitric oxide in normal pressure glaucoma. Acta Ophthalmologica Scandinavica, 78: 37-38.
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71:   Galassi, F., E. Masini, B. Giambene, F., Fabrizi, C. Uliva, M. Bolla and E. Ongini, 2006. A topical nitric oxide-releasing dexamethasone derivative: Effects on intraocular pressure and ocular haemodynamics in a rabbit glaucoma model. Br. J. Ophthalmol., 90: 1414-1419.
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72:   Galassi, F., G. Renieri, A. Sodi, F. Ucci, L. Vannozzi and E. Masini, 2004. Nitric oxide proxies and ocular perfusion pressure in primary open angle glaucoma. Br. J. Ophthalmol., 88: 757-760.
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73:   Gallo, O., A. Franchi, L. Magnelli, I. Sardi and A. Vannacci et al., 2001. Cyclooxygenase-2 pathway correlates with VEGF expression in head and neck cancer. Implications for tumor angiogenesis and metastasis. Neoplasia, 3: 53-61.
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74:   Gallo, O., E. Masini, B. Bianchi, L. Bruschini, M. Paglierani and A. Franchi, 2002. Prognostic significance of cyclooxygenase-2 pathway and angiogenesis in head and neck squamous cell carcinoma. Hum. Pathol., 33: 708-714.
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75:   Gallo, O., I. Fini-Storchi, W.A. Vergari, E. Masini, L. Morbidelli, M. Ziche and A. Franchi, 1998. Role of nitric oxide in angiogenesis and tumor progression in head and neck cancer. J. Natl. Cancer Inst., 90: 587-596.
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76:   Gallo, O., I. Sardi, E. Masini and A. Franchi, 1999. Relationship between p53 mutation and inducible nitric oxide synthase expression in human colorectal cancer. J. Natl. Cancer Inst., 91: 1509-1510.
77:   Gallo, O., N. Schiavone, L. Papucci, I. Sardi and L. Magnelli et al., 2003. Down-regulation of nitric oxide synthase-2 and cyclooxygenase-2 pathways by p53 in squamous cell carcinoma. Am. J. Pathol., 163: 723-732.
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78:   Gambassi, F., A. Pistelli, M.G. Di Bello, M. Lupini, P.F. Mannaioni and E. Masini, 1992. Ischemia-reperfusion injury and histamine release in isolated perfused guinea-pig heart: Effects of nitric oxide generators. Pharmacol. Res., 1: 11-12.
79:   Gambassi, F., M. Lupini, M.G. di Bello, L. Mugnai, E. Masini and P.F. Mannaioni, 1993. Histamine release by free radicals: Effect of defibrotide (DFT) and its fraction Agents Action, 38: C206-C208.
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80:   Giannella, E., E. Masini, B. Palmerani, A. Pistelli and P.F. Mannaioni, 1988. Modulation of anaphylactic histamine release by calcium channel agonists and antagonists. Agents Actions, 23: 185-187.
PubMed  |  
81:   Giannini, L., A. Vannacci, A. Missanelli, R. Mastroianni, P.F. Mannaioni, F. Moroni and E. Masini, 2007. Amatoxin poisoning: A 15-year retrospective analysis and follow-up evaluation of 105 patients. Clin. Toxicol., 45: 539-542.
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82:   Giannini, L., R. Mastroianni, C. Mariottini, M.B. Passani, S. Nistri, P.F. Mannaioni and E. Masini, 2007. Activation of cannabinoid receptors reduces Allergen-induced oxidative stress damage during Asthma-like reaction in sensitised Guinea-pigs. Inflammation Res., 56: S11-S12.
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83:   Giannini, L., S. Nistri, R. Mastroianni, L. Cinci and A. Vannacci et al., 2008. Activation of cannabinoid receptors prevents Antigen-induced Asthma-like reaction in guinea pigs. J. Cell. Mol. Med., 12: 2381-2394.
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84:   Impagnatiello, F., B. Giambene, C. Lanzi, A. Pini and T. Somma et al., 2012. The nitric oxide donating triamcinolone acetonide NCX 434 does not increase intraocular pressure and reduces endothelin-1 induced biochemical and functional changes in the rabbit eye. Br. J. Ophthalmol., 96: 757-761.
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85:   La Villa, G., G. Barletta, P. Pantaleo, R. Del Bene and F. Vizzutti et al., 2001. Hemodynamic, renal and endocrine effects of acute inhibition of nitric oxide synthase in compensated cirrhosis. Hepatology, 34: 19-27.
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86:   Laffi, G., M. Foschi, E. Masini, A. Simoni and L. Mugnai et al., 1995. Increased production of nitric oxide by neutrophils and monocytes from cirrhotic patients with ascites and hyperdynamic circulation. Hepatology, 22: 1666-1673.
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87:   Ledda, F., P. Blandina, P. Botti, L. Caramelli and R. Fantozzi et al., 1983. Overall evaluation of treatment modalities for heroin addiction in a toxicology unit. Subst Alcohol. Actions Misuse, 4: 283-304.
PubMed  |  
88:   Lorenzi, P., M. Marsili, S. Boncinelli, L.P. Fabbri and P. Fontanari et al., 1999. Searching for a general anaesthesia protocol for rapid detoxification from opioids. Eur. J. Anaesthesiol., 16: 719-727.
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89:   Luceri, C., L. Giannini, M. Lodovici, E. Antonucci, R. Abbate, E. Masini and P. Dolara, 2007. p-Coumaric acid, a common dietary phenol, inhibits platelet activity in vitro and in vivo. Br. J. Nutr., 97: 458-463.
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90:   Lupini, M., F. Gambassi, L. Mugnai, S. Bianchi, E. Masini and P.F. Mannaioni, 1992. Defibrotide decreases histamine release in guinea-pig model of myocardial ischemia and reperfusion in vitro. Agents Actions, 38: 333-335.
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91:   Manera, C., G. Saccomanni, B. Adinolfi, V. Benetti and A. Ligresti et al., 2009. Rational design, synthesis and pharmacological properties of new 1, 8-naphthyridin-2 (1 H)-on-3-carboxamide derivatives as highly selective cannabinoid-2 receptor agonists. J. Med. Chem., 52: 3644-3651.
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92:   Mannaioni, P.F. and E. Masini, 1988. The release of histamine by free radicals. Free Radic Biol. Med., 5: 177-197.
PubMed  |  
93:   Mannaioni, P.F., A. Pistelli, F. Gambassi, M.G. Di Bello, S. Rasoanti and E. Masini, 1991. Maste cells as paraneurons: The endogenous control of histaminerelease. J. Chemother, 3: 48-51.
94:   Mannaioni, P.F., A. Pistelli, F. Gambassi, M.G. Di Bello, S. Raspanti and E. Masini, 1991. A place for free radicals in platelet-derived histamine releasing factor (PDHRF) and evidence that histaminergic receptors modulate platelet aggregation. Agents Actions, 33: 57-60.
PubMed  |  
95:   Mannaioni, P.F., A. Pistelli, F. Gambassi, M.G. Di Bello, S. Raspanti and E. Masini, 1991. Definition of platelet-derived histamine-releasing factor and histaminergic receptors modulating platelet aggregation. Int. Arch. Allergy Applied Immunol., 94: 301-302.
PubMed  |  
96:   Mannaioni, P.F., A. Pistelli, M.G. Di Bello, F. Gambassi and E. Masini, 1992. H1-receptors dependent increase in platelet aggregation is mediated by intracellular calcium. Agents Actions, 38: 401-405.
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97:   Mannaioni, P.F., A. Vannacci and E. Masini, 2006. Carbon monoxide: The bad and the good side of the coin, from neuronal death to anti-inflammatory activity. Inflammation Res., 55: 261-273.
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98:   Mannaioni, P.F., B. Palmerani, A. Pistelli, F. Gambassi, E. Giannella, T. Bani Sacchi and E. Masini, 1990. Histamine release by platelet aggregation. Agents Actions, 30: 44-48.
PubMed  |  
99:   Mannaioni, P.F., E. Giannella, B. Palmerani, A. Pistelli and F. Gambassi et al., 1988. Free radicals as endogenous histamine releasers. Agents Actions, 23: 129-142.
PubMed  |  
100:   Mannaioni, P.F., E. Masini, A. Pistelli, D. Salvemini and J.R. Vane, 1991. Mast cells as a source of superoxide anions and nitric oxide-like factor: Relevance to histamine release. Int. J. Tissue React., 13: 271-278.
PubMed  |  
101:   Mannaioni, P.F., F. Gambassi, M.G. di Bello, P. Botti and L. Caramelli et al., 1994. Il gamma idrossibutirrato (GHB) nella medicina delle farmaco tossicodipendenze. Eur. J. Alcohol Stud., 4: 66-66.
102:   Mannaioni, P.F., F. Moroni, R. Fantozzi and E. Masini, 1975. Studies on the 14C-histamine release induced by noradrenaline in mouse neoplastic mast cells. Agents Actions, 5: 417-423.
PubMed  |  
103:   Mannaioni, P.F., M.G. Bello, M.G. di Bello, C. Mirabella, P. Gai, W. Schunack and E. Masini, 1997. Interaction between histamine and nitric oxide in rat mast cells and in isolated guinea pig hearts. Int. Arch. Allergy Immunol., 113: 297-299.
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104:   Mannaioni, P.F., M.G. Bello, M.G. di Bello, W. Schunack and E. Masini, 1997. Histamine up-regulates the generation of nitric oxide and nitric oxide down-regulates the release of histamine in cardiovascular preparations. Inflamm. Res., 46: S97-S78.
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105:   Mannaioni, P.F., M.G. Di Bello, S. Raspanti, F. Gambassi, L. Mugnai and E. Masini, 1992. Platelet histamine: Characterization of the proaggregatory effect of histamine in human platelets. Int. Arch. Allergy Immunol., 99: 394-396.
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106:   Mannaioni, P.F., M.G. di Bello and E. Masini, 1997. Platelets and inflammation: Role of platelet-derived growth factor, adhesion molecules and histamine. Inflamm. Res., 46: 4-18.
PubMed  |  Direct Link  |  
107:   Mannaioni, P.F., M.G. di Bello, S. Raspanti, L. Mugnai, V. Romano and E. Masini, 1995. Activation of xenobiotics into free radicals by prostaglandin-H-synthase and by rat liver microsomes. Adv. Prostaglandin Thromboxane Leukot Res., 23: 215-217.
PubMed  |  Direct Link  |  
108:   Mannaioni, P.F., M.G. di Bello, S. Raspanti, L. Mugnai, V. Romano and E. Masini, 1996. Free radical mediated release of histamine from rat mast cells induced by drugs of abuse. Inflamm. Res., 45: S25-S26.
PubMed  |  Direct Link  |  
109:   Mannaioni, P.F., M.G. di Bello, S. Raspanti, V. Romano, T.B. Sacchi, P. Cappugi and E. Masini, 1995. Storage and release of histamine in human platelets. Inflamm. Res., 44: S16-S17.
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110:   Mannaioni, P.F., R. Fantozzi, E. Giannella and E. Masini, 1988. Pathophysiological significance of the distribution of histamine receptor sub-types: A proposed dual role for histamine in inflammation and type I hypersensitivity reactions. Agents Actions, 24: 26-34.
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111:   Mannaioni, P.P.F., M.G. di Bello, S. Raspanti, F. Gambassi, L. Mugnai and E. Masini, 1993. Histamine release by human platelets. Agents Actions, 38:: C203-C205.
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112:   Marzocca, C., A. Vannacci, S. Cuzzocrea, D. Salvemini, P.F. Mannaioni and E. Masini, 2003. Effects of the SOD mimetic, M40403, on prostaglandin production in an in vivo model of ischemia and reperfusion in rat heart. Inflamm. Res., 52: 23-24.
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113:   Masini, E., A. Pistelli, M.G. Di Bello, S. Raspanti and P.F. Mannaioni, 1992. Influence of aging on mast cells production of a nitric oxide-like factor: Comparison between normal and hypertensive rats. Agents Actions, 36: C268-C271.
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114:   Masini, E., A. Vannacci, C. Marzocca, P. Francesco Mannaioni and O. Befani et al., 2002. A plant histaminase modulates cardiac anaphylactic response in guinea pig. Biochem. Biophys. Res. Commun., 296: 840-846.
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115:   Masini, E., A. Vannacci, C. Marzocca, S. Pierpaoli and L. Giannini et al., 2003. Heme oxygenase-1 and the ischemia-reperfusion injury in the rat heart. Exp. Biol. Med., 228: 546-549.
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116:   Masini, E., A. Vannacci, L. Giannini, O. Befani and S. Nistri et al., 2004. Effect of a plant histaminase on asthmalike reaction induced by inhaled antigen in sensitized guinea pig. Eur. J. Pharmacol., 502: 253-264.
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117:   Masini, E., A. Vannacci, P. Failli, R. Mastroianni and L. Giannini et al., 2008. A carbon Monoxide-releasing molecule (CORM-3) abrogates polymorphonuclear Granulocyte-induced activation of endothelial cells and mast cells. FASEB J., 22: 3380-3388.
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118:   Masini, E., B. Palmerani, F. Gambassi, A. Pistelli and E. Giannella et al., 1990. Histamine release from rat mast cells induced by metabolic activation of polyunsaturated fatty acids into free radicals. Biochem. Pharmacol., 39: 879-889.
PubMed  |  
119:   Masini, E., B. Palmerani, T. Bani-Sacchi, E. Giannella, R. Fantozzi and P.F. Mannaioni, 1987. Mast cell histamine release induced by intermediate products of arachidonic acid metabolism. Int. Arch. Allergy Applied Immunol., 82: 279-282.
PubMed  |  
120:   Masini, E., D. Bani, A. Vannacci, S. Pierpaoli and P.F. Mannaioni et al., 2005. Reduction of antigen-induced respiratory abnormalities and airway inflammation in sensitized guinea pigs by a superoxide dismutase mimetic. Free Radic. Biol. Med., 39: 520-531.
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121:   Masini, E., D. Bani, I. Sardi, R. Baronti, T. Bani-Sacchi, M. Bigazzi and P.F. Mannaioni, 2000. Dual role of nitric oxide in myocardial ischemia-reperfusion. Inflamm. Res., 49: 78-79.
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122:   Masini, E., D. Bani, M. Bigazzi, P.F. Mannaioni and T. Bani-Sacchi, 1994. Effects of relaxin on mast cells. In vitro and In vivo studies in rats and guinea pigs. J. Clin. Invest., 94: 1974-1980.
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123:   Masini, E., D. Bani, M.G. Bello, M. Bigazzi, P.F. Mannaioni and T.B. Sacchi, 1997. Relaxin counteracts myocardial damage induced by ischemia-reperfusion in isolated guinea pig hearts: Evidence for an involvement of nitric oxide. Endocrinology, 138: 4713-4720.
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124:   Masini, E., D. Salvemini, A. Pistelli, P.F. Mannaioni and J.R. Vane, 1991. Rat mast cells synthesize a nitric oxide like-factor which modulates the release of histamine. Agents Actions, 33: 61-63.
PubMed  |  
125:   Masini, E., D. Salvemini, J.F. Ndisang, P. Gai and L. Berni Et Al., 1999. Cardioprotective activity of endogenous and exogenous nitric oxide on ischaemia reperfusion injury in isolated guinea pig hearts. Inflamm. Res., 48: 561-568.
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126:   Masini, E., D. Salvemini, L. Mugnai, M.G. Bello, D. Bani and P.F. Mannaioni, 1996. The effectof relaxin on myocardial ischaemia-reperfusion injury and histamine release In vitro and In vivo. Inflamm. Res., 45: S27-S28.
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127:   Masini, E., E. Giannella, A. Pistelli, B. Palmerani, F. Gambassi, B. Occupati and P.F. Mannaioni, 1989. Histamine release by free radicals: The relationship with the signal transduction system. Agents Actions, 27: 72-74.
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128:   Masini, E., E. Giannella, B. Palmerani, A. Pistelli, F. Gambassi and P.F. Mannaioni, 1989. Free radicals induce ischemia-reperfusion injury and histamine release in the isolated guinea pig heart. Int. Arch. Allergy Applied Immunol., 88: 132-133.
PubMed  |  
129:   Masini, E., E. Giannella, B. Palmerani, A. Pistelli, F. Gambassi and P.F. Mannaioni, 1989. Prostaglandin H synthetase activates xenobiotics into free radicals: Histamine release and biochemical characteristics. Int. Arch. Allergy Applied Immunol., 88: 134-135.
PubMed  |  
130:   Masini, E., E. Giannella, S. Bianchi and P.F. Mannaioni, 1987. Histamine and lactate dehydrogenase (LDH) release in ischemic myocardium of the guinea-pig. Agents Actions, 20: 281-283.
PubMed  |  
131:   Masini, E., E. Giannella, S. Bianchi, B. Palmerani, A. Pistelli and P.F. Mannaioni, 1988. Histamine release in acute coronary occlusion-reperfusion in isolated guinea-pig heart. Agents Actions, 23: 266-269.
PubMed  |  
132:   Masini, E., E. Giannella, T. Bani-Sacchi, R. Fantozzi, B. Palmerani and P.F. Mannaioni, 1987. Histamine release from serosal mast cells by intermediate products of arachidonic acid metabolism. Agents Actions, 20: 202-225.
PubMed  |  
133:   Masini, E., E. Ragazzo, M.C. Vinci, S. Nistri and L. Cinci et al., 2009. A selective H 4 R antagonist prevents antigen-induced asthma-like reaction and airway inflammation in guinea pigs. Inflammat. Res., 58: 9-10.
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134:   Masini, E., F. Carta, A. Scozzafava and C.T. Supuran, 2013. Antiglaucoma carbonic anhydrase inhibitors: A patent review. Expert Opin. Ther. Pat., 23: 705-716.
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135:   Masini, E., F. Franconi, V.A. Peduto, E. Pieraccioli, R. Matucci and G.P. Novelli, 1986. Liver function following hypovolemic hypotension in rats anaesthetized with halothane or enflurane. Pharmacol. Res. Commun., 18: 847-856.
PubMed  |  
136:   Masini, E., F. Gambassi, E. Giannella, B. Palmerani, A. Pistelli, L. Carlomagno and P.F. Mannaioni, 1989. Ischemia-reperfusion injury and histamine release in isolated guinea-pig heart: The role of free radicals. Agents Actions, 27: 154-157.
PubMed  |  
137:   Masini, E., F. Gambassi, M. Lupini, A. Pistelli and P.F. Mannaioni, 1992. Correlation between nitric oxide synthesis and histamine release in mast cells from spontaneously hypertensive rats: Influence of aging. Int. Arch. Allergy Immunol., 99: 404-407.
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138:   Masini, E., F. Gambassi, M.G. di Bello, L. Mugnai, S. Raspanti and P.F. Mannaioni, 1994. Nitric oxide modulates cardiac and mast cell anaphylaxis. Agents Actions, 41: C89-C90.
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139:   Masini, E., F. Gambassi, S. Bianchi, L. Mugnai, M. Lupini, A. Pistelli and P.F. Mannaioni, 1991. Effect of nitric oxide generators on ischemia-reperfusion injury and histamine release in isolated perfused guinea pig heart. Int. Arch. Allergy Applied Immunol., 94: 257-258.
PubMed  |  
140:   Masini, E., G. Luciani, P. Blandina, G. Fabrizi, A. Becucci, G. Minnini and P.F. Mannaioni, 1982. No evidence of opiate-like withdrawal by naloxone in subjects treated chronically with clonidine. Int. J. Clin. Pharm. Res., 2: 27-31.
141:   Masini, E., G. Zagli, J.F. Ndisang, M. Solazzo, P.F. Mannaioni and D. Bani, 2002. Protective effect of relaxin in cardiac anaphylaxis: Involvement of the nitric oxide pathway. Br. J. Pharmacol., 137: 337-344.
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142:   Masini, E., J. Phanchenault, F. Pezziardi, P. Gautier and J.P. Gagnol, 1985. Histamine release during an experimental coronary thrombosis in awake dog. Agents Actions, 16: 227-230.
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143:   Masini, E., J. Planchenault, F. Pezziardi, P. Gautier and J.P. Gagnol, 1985. Histamine-releasing properties of Polysorbate 80 in vitro and in vivo: Correlation with its hypotensive action in the dog. Agents Actions, 16: 470-477.
PubMed  |  
144:   Masini, E., L. Giannini, S. Nistri, L. Cinci and R. Mastroianni et al., 2008. Ceramide: A key signaling molecule in a Guinea pig model of allergic asthmatic response and airway inflammation. J. Pharmacol. Exp. Ther., 324: 548-557.
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145:   Masini, E., L. Mugnai, M. Foschi, G. Laffi, P. Gentilini and P.F. Mannaioni, 1995. Changes in the production of nitric oxide and superoxide by inflammatory cells in liver cirrhosis. Int. Arch. Allergy Immunol., 107: 197-198.
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146:   Masini, E., L. Rucci, M.B. Cirri-Borghi, E. Giannella and P.F. Mannaioni, 1986. Stimulation and resection of Vidian nerve in patients with chronic hypertrophic non-allergic rhinitis: Effect on histamine content in nasal mucosa. Agents Actions, 18: 251-253.
PubMed  |  
147:   Masini, E., M. Fazi, R. Baronti, P.F. Mannaioni and P. Bechi, 1999. Role of nitric oxide and histamine in the reflux-related gastric mucosal injury in the rat. Inflamm. Res., 48: 102-103.
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148:   Masini, E., M. Lodovici, R. Fantozzi, S. Brunelleschi, A. Conti and P.F. Mannaioni, 1986. Histamine release by free radicals: Paracetamol-induced histamine release from rat peritoneal mast cells after in vitro activation by monooxygenase. Agents Actions, 18: 85-88.
PubMed  |  
149:   Masini, E., M. Lupini, L. Mugnai, S. Raspanti and P.F. Mannaioni, 1995. Polydeoxyribonucleotides and nitric oxide release from guinea-pig hearts during ischaemia and reperfusion. Br. J. Pharmacol., 115: 629-635.
PubMed  |  Direct Link  |  
150:   Masini, E., M.G. Di Bello, S. Raspanti, J.F. Ndisang, R. Baronti, P. Cappugi and P.F. Mannaioni, 1998. The role of histamine in platelet aggregation by physiological and immunological stimuli. Inflamm. Res., 47: 211-220.
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151:   Masini, E., M.G. di Bello, A. Pistelli, S. Raspanti and F. Gambassi et al., 1994. Generation of nitric oxide from nitrovasodilators modulates the release of histamine from mast cells. J. Physiol. Pharmacol., 45: 41-53.
PubMed  |  Direct Link  |  
152:   Masini, E., M.G. di Bello, D. Bani, M. Bigazzi, T.B. Sacchi and P.F. Mannaioni, 1995. Relaxin inhibits histamine release from mast cells: Involvement of nitric oxide production. Inflamm. Res., 44: S12-S13.
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153:   Masini, E., M.G. di Bello, L. Mugnani and P.F. Mannaioni, 1994. Anaphylaxis in human platelets. Br. J. Pharm., 111: 77P-77P.
154:   Masini, E., M.G. di Bello, P. Cappugi, L. Berni, C. Mirabella and P.F. Mannaioni, 1997. Platelet aggregation and platelet histamine release by immunological stimulation in atopic patients: Modulation by nitric oxide. Inflamm. Res., 46: S81-S82.
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155:   Masini, E., M.G. di Bello, S. Raspanti, T.B. Sacchi, E. Maggi and P.F. Mannaioni, 1994. Platelet aggregation and histamine release by immunological stimuli. Immunopharmacology, 28: 19-29.
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156:   Masini, E., P. Bechi, R. Dei, M.G. di Bello and T.B. Sacchi, 1994. Helicobacter pylori potentiates histamine release from rat serosal mast cells induced by bile acids. Dig. Dis. Sci., 39: 1493-1500.
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157:   Masini, E., P. Bechi, R. Dei, T. Vardar, M.G. di Bello, S. Raspanti and P.F. Mannaioni, 1993. Helicobacter pylori potentiates histamine release from rat serosal mast cells. Agents Actions, 38: C197-C199.
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158:   Masini, E., P. Blandina and P.F. Mannaioni, 1982. Mast cell receptors controlling histamine release: Influences on the mode of action of drugs used in the treatment of adverse drug reactions. Klin. Wochenschr, 60: 1031-1038.
PubMed  |  
159:   Masini, E., P. Blandina and P.F. Mannaioni, 1982. Removal of alpha-amanitin from blood by hemoperfusion over uncoated charcoal. Experimental results. Contrib Nephrol., 29: 76-81.
PubMed  |  
160:   Masini, E., P. Blandina, P.F. Mannaioni and G. Luciani, 1981. Clonidine and naloxone for rapid opiate detoxication: Comparison between treatments. Clin. Toxicol., 18: 1021-1026.
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161:   Masini, E., P. Blandina, R. Fantozzi, S. Brunelleschi and P.F. Mannaioni, 1981. Correlation between cholinergic histamine release and quinuclidinyl-benzilate ([3H]-QNB) binding in mast cell membranes. Agents Actions, 11: 55-59.
PubMed  |  
162:   Masini, E., P. Blandina, S. Brunelleschi and P.F. Mannaioni, 1982. Evidence for H2-receptor-mediated inhibition of histamine release from isolated rat mast cells. Agents Actions, 12: 85-88.
PubMed  |  
163:   Masini, E., P.F. Mannaioni, A. Pistelli, D. Salvemini and J.R. Vane, 1991. Impairment of the L-arginine-nitric oxide pathway in mast cells from spontaneously hypertensive rats. Biochem. Biophys. Res. Commun., 177: 1178-1182.
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164:   Masini, E., R. Fantozzi, A. Conti, P. Blandina, S. Brunelleschi and P.F. Mannaioni, 1985. Immunological modulation of cholinergic histamine release in isolated rat mast cells. Agents Actions, 16: 152-154.
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165:   Masini, E., R. Fantozzi, A. Conti, P. Blandina, S. Brunelleschi and P.F. Mannaioni, 1985. Mast cell heterogeneity in response to cholinergic stimulation. Int. Arch. Allergy Applied Immunol., 77: 184-185.
PubMed  |  
166:   Masini, E., R. Fantozzi, P. Blandina, A. Galli and T. Bani-Sacchi et al., 1982. Presence of functionally active β-adrenoceptors in rat mast cells. Naunyn Schmiedebergs Arch. Pharmacol., 321: 171-176.
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167:   Masini, E., R. Fantozzi, P. Blandina, F. Ledda, F. Moroni and P. Mannaioni, 1981. Epidemiological survey of intoxications in Florence in the last ten years. Clin. Toxicol., 18: 1157-1162.
PubMed  |  
168:   Masini, E., R. Fantozzi, P. Blandina, S. Brunelleschi and P.F. Mannaioni, 1982. Muscarinic cholinergic stimulation. Agents Actions, 13: 179-182.
169:   Masini, E., R. Fantozzi, P. Blandina, S. Brunelleschi and P.F. Mannaioni, 1985. The riddle of cholinergic histamine release from mast cells. Prog. Med. Chem., 22: 267-291.
PubMed  |  
170:   Masini, E., S. Bianchi, F. Gambassi, B. Palmerani, A. Pistelli, L. Carlomagno and P.F. Mannaioni, 1990. Ischemia reperfusion injury and histamine release in isolated and perfused guinea-pig heart: Pharmacological interventions. Agents Actions, 30: 198-201.
PubMed  |  
171:   Masini, E., S. Bianchi, L. Mugnai, F. Gambassi, M. Lupini, A. Pistelli and P.F. Mannaioni, 1991. The effect of nitric oxide generators on ischemia reperfusion injury and histamine release in isolated perfused guinea-pig heart. Agents Actions, 33: 53-56.
PubMed  |  
172:   Masini, E., S. Cuzzocrea, D. Bani, E. Mazzon and C. Muja et al., 2007. Beneficial effects of a plant histaminase in a rat model of splanchnic artery occlusion and reperfusion. Shock, 27: 409-415.
173:   Masini, E., S. Cuzzocrea, E. Mazzon, C. Marzocca, P.F. Mannaioni and D. Salvemini, 2002. Protective effects of M40403, a selective superoxide dismutase mimetic, in myocardial ischaemia and reperfusion injury in vivo. Br. J. Pharmacol., 136: 905-917.
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174:   Masini, E., S. Cuzzocrea, E. Mazzon, C. Muia, A. Vannacci, F. Fabrizi and D. Bani, 2006. Protective effects of relaxin in ischemia/reperfusion‐induced intestinal injury due to splanchnic artery occlusion. Br. J. Pharmacol., 148: 1124-1132.
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175:   Masini, E., S. Nistri, A. Vannacci, T.B. Sacchi, A. Novelli and D. Bani, 2004. Relaxin inhibits the activation of human neutrophils: involvement of the nitric oxide pathway. Endocrinology, 145: 1106-1112.
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176:   Masini, E., S. Pierpaoli, C. Marzocca, P.F. Mannaioni and P. Pietrangeli et al., 2003. Protective effects of a plant histaminase in myocardial ischaemia and reperfusion injury in vivo. Biochem. Biophys. Res. Commun., 309: 432-439.
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177:   Masini, E., V. Fabbroni, L. Giannini, A. Vannacci and L. Messerini et al., 2005. Histamine and histidine decarboxylase up-regulation in colorectal cancer: Correlation with tumor stage. Inflammation Res., 54: S80-S81.
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178:   Mincione, F., F. Benedini, S. Biondi, A. Cecchi and C. Temperini et al., 2011. Synthesis and crystallographic analysis of new sulfonamides incorporating NO-donating moieties with potent antiglaucoma action. Bioorganic Med. Chem. Lett., 21: 3216-3221.
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179:   Mincione, F., M. Starnotti, E. Masini, L. Bacciottini and C. Scrivanti et al., 2005. Carbonic anhydrase inhibitors: Design of thioureido sulfonamides with potent isozyme II and XII inhibitory properties and intraocular pressure lowering activity in a rabbit model of glaucoma. Bioorg. Med. Chem. Lett., 15: 3821-3827.
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180:   Mirabella, C., J.F. Ndisang, L.A. Berni, P. Gai, E. Masini and P.F. Mannaioni, 1999. Modulation of the immunological activation of human basophils by carbon monoxide. Inflamm. Res., 48: 11-12.
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181:   Mirabella, C., R. Baronti, L.A. Berni, P. Gai, J.F. Ndisang, E. Masini and P.F. Mannaioni, 1999. Hemin and carbon monoxide modulate the immunological response of human basophils. Int. Arch. Allergy Immunol., 118: 259-260.
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182:   Mollace, V., C. Muscoli, E. Masini, S. Cuzzocrea and D. Salvemini, 2005. Modulation of prostaglandin biosynthesis by nitric oxide and nitric oxide donors. Pharmacol. Rev., 57: 217-252.
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183:   Moncini, M., E. Masini, F. Gambassi and P.F. Mannaioni, 2000. Gamma-hydroxybutyric acid and alchol-related syndromes. Alcohol, 20: 1-7.
184:   Mondovi, B., P. Pietrangeli, L. Morpurgo, E. Masini and R. Federico et al., 2003. Some new functions of amine oxidases. Inflammopharmacology, 11: 155-163.
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185:   Mondovi, B., W.A. Fogel, R. Federico, C. Calinescu, M.A. Mateescu, A.C. Rosa and E. Masini, 2013. Effects of amine oxidases in allergic and Histamine-mediated conditions. Recent Patents Inflammat. Allergy Drug Discovery, 7: 20-34.
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186:   Morbidelli, L., A. Parenti, E. Masini, H.J. Granger and M. Ziche, 1994. Effect of substance P and [Sar^9]-Sp-Sulfone on cyclic GMP accumulation in cultured coronary capillary endothelial cells. Neuropeptides, 26: 1-72.
187:   Moroni, F., R. Fantozzi, E. Masini and P.F. Mannaioni, 1975. Studies on the 14C-histamine release induced by histamine in mouse neoplastic mast cells. Agents Actions, 5: 424-426.
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188:   Moroni, F., R. Fantozzi, E. Masini and P.F. Mannaioni, 1976. A trend in the therapy of Amanita phalloides poisoning. Arch. Toxicol., 36: 111-115.
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189:   Moroni, F., R. Fantozzi, E. Masini and P.F. Mannaioni, 1977. The influence of catecholamines and serotonin on histamine uptake and metabolism by guinea pig atrium. Eur. J. Pharmacol., 41: 59-63.
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190:   Moroni, F., R. Fantozzi, E. Masini and P.F. Mannaioni, 1977. The modulation of histamine release by alpha-adrenoceptors: Evidences in murine neoplastic mast cells. Agents Actions, 7: 57-61.
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191:   Muscoli, C., V. Mollace, J. Wheatley, E. Masini, M. Ndengele, Z.Q. Wang and D. Salvemini, 2004. Superoxide-mediated nitration of spinal manganese superoxide dismutase: A novel pathway in N-methyl-D-aspartate-mediated hyperalgesia. Pain, 111: 96-103.
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192:   Ndengele, M.M., S. Cuzzocrea, E. Masini, M.C. Vinci and E. Esposito et al., 2009. Spinal ceramide modulates the development of morphine antinociceptive tolerance via peroxynitrite-mediated nitroxidative stress and neuroimmune activation. J. Pharmacol. Exp. Ther., 329: 64-75.
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193:   Ndisang, J.F., M. Moncini, P. Gai, L. Berni, G. Cecere, E. Masini and P.F. Mannaioni, 2000. Induction of heme oxygenase provides protection against cardiac anaphylaxis. Inflamm. Res., 49: 76-77.
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194:   Ndisang, J.F., P. Gai, L. Berni, C. Mirabella, R. Baronti, P.F. Mannaioni and E. Masini, 1999. Modulation of the immunological response of guinea pig mast cells by carbon monoxide. Immunopharmacology, 43: 65-73.
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195:   Ndisang, J.F., R. Baronti, G. Cecere, E. Masini, D. Bani and P.F. Mannaioni, 2001. Relaxin generates nitric oxide and provides protection against cardiac anaphylaxis. Inflamm. Res., 50: 122-123.
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196:   Ndisang, J.F., R. Wang, A. Vannacci, C. Marzocca and O. Fantappie et al., 2001. Haeme oxygenase‐1 and cardiac anaphylaxis. Br. J. Pharmacol., 134: 1689-1696.
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197:   Nistri, S., L. Cinci, A.M. Perna, E. Masini, R. Mastroianni and D. Bani, 2008. Relaxin induces mast cell inhibition and reduces ventricular arrhythmias in a swine model of acute myocardial infarction. Pharmacol. Res., 57: 43-48.
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198:   Palmerani, B., A. Pistelli, F. Gambassi, E. Giannella, E. Masini and P.F. Mannaioni, 1988. Histamine release by free radicals during prostaglandin-H-synthetase dependent oxidation of xenobiotics. Pharmacol. Res. Commun., 20: 437-438.
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199:   Peduto, V.A., E. Masini, M. Ludovici, E. Pieraccioli, P. Dolara and G.P. Novelli, 1983. Stimulation of drug-metabolizing enzymes by nitrous oxide in the rat. Acta Anaesthesiol Scand, 27: 439-442.
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200:   Pellegrini-Giampietro, D.E., F. Moroni, A. Pistelli, B. Palmerani and A.M. Zorn et al., 1989. Pyrrolidone carboxylic acid in acute and chronic alcoholism. Preclinical and clinical studies. Recenti Prog. Med., 80: 160-164.
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201:   Perna, A., E. Masini, S. Nistri, T. Bani Sacchi, M. Bigazzi and D. Bani, 2005. Human recombinant relaxin reduces heart injury and improves ventricular performance in a swine model of acute myocardial infarction. Ann. N. Y. Acad. Sci., 1041: 431-433.
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202:   Perna, A.M., E. Masini, S. Nistri, V. Briganti and L. Chiappini et al., 2005. Novel drug development opportunity for relaxin in acute myocardial infarction: Evidences from a swine model. FASEB J., 19: 1525-1527.
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203:   Perrino, E., C. Uliva, C. Lanzi, P.D. Soldato, E. Masini and A. Sparatore, 2009. New prostaglandin derivative for glaucoma treatment. Bioorganic Med. Chem. Lett., 19: 1639-1642.
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204:   Pierpaoli, S., C. Marzocca, M.G. Bello, W. Schunack, P.F. Mannaioni and E. Masini, 2003. Histaminergic receptors modulate the coronary vascular response in isolated guinea pig hearts. Role of nitric oxide. Inflamm. Res., 52: 390-396.
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205:   Pini, A., G. Mannaioni, D. Pellegrini-Giampietro, M. Beatrice Passani, R. Mastroianni, D. Bani and E. Masini, 2012. The role of cannabinoids in inflammatory modulation of allergic respiratory disorders, inflammatory pain and ischemic stroke. Current Drug Targets, 13: 984-993.
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206:   Pini, A., S. Viappiani, M. Bolla, E. Masini and D. Bani, 2012. Prevention of Bleomycin-induced lung fibrosis in mice by a novel approach of parallel inhibition of cyclooxygenase and nitric-oxide donation using NCX 466, a prototype cyclooxygenase inhibitor and nitric-oxide donor. J. Pharmacol. Exp. Ther., 341: 493-499.
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207:   Pistelli, A., M.G. di Bello, S. Raspanti, E. Masini and P.F. Mannaioni, 1993. New pharmacological profiles of loratadine: Effects on platelet aggregation and histamine release from repository cells. Agents Actions, 38: C200-C202.
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208:   Richter, J.E., R. Penagini, D. Pohl, K. Dvorak and A. Goldman et al., 2011. Barrett's esophagus: Proton pump inhibitors and chemoprevention II. Ann. N. Y. Acad. Sci., 1232: 114-139.
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209:   Rucci, L., E. Masini, M.B. Cirri Borghi, E. Giannella and P.F. Mannaioni, 1988. Histamine release from nasal mucosal mast cells in patients with chronic hypertrophic non-allergic rhinitis, after parasympathetic nerve stimulation. Agents Actions, 25: 314-320.
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210:   Rucci, L., E. Masini, R. Arbi Riccardi, E. Giannella and C. Fioretti et al., 1989. Vidian nerve resection, histamine turnover and mucosal mast cell function in patients with chronic hypertrophic non-allergic rhinitis. Agents Actions, 28: 224-230.
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211:   Rucci, L., M.B. Borghi Cirri, E. Masini and O. Fini Storchi, 1985. Vidian nerve resection in chronic hypertrophic non allergic rhinitis: Effects on histamine content, number and rate of degranulation processes of mast cells in nasal mucosa. Rhinology, 23: 309-314.
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212:   Salvemini, D., E. Masini, A. Pistelli, P.F. Mannaioni and J.R. Vane, 1991. Nitric oxide: A regulatory mediator of mast cells reactivity. J. Cariovasc Pharmacol., 17: 258-264.
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213:   Salvemini, D., E. Masini, E. Anggard, P.F. Mannaioni and J. Vane, 1990. Synthesis of a nitric oxide-like factor from L-arginine by rat serosal mast cells: Stimulation of guanylate cyclase and inhibition of platelet aggregation. Biochem. Biophys. Res. Commun., 169: 596-601.
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214:   Somma, T., L. Cinci, G. Formicola, A. Pini and R. Thurmond et al., 2013. A selective antagonist of histamine H4 receptors prevents antigen-induced airway inflammation and bronchoconstriction in guinea pigs: Involvement of lipocortin-1. Br. J. Pharmacol., 170: 200-213.
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215:   Suzuki, Y., E. Masini, C. Mazzocca, S. Cuzzocrea, A. Ciampa, H. Suzuki and D. Bani, 2004. Inhibition of poly (ADP-ribose) polymerase prevents allergen-induced asthma-like reaction in sensitized Guinea pigs. J. Pharmacol. Exp. Therap., 311: 1241-1248.
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216:   Tarquini, R., E. Masini, G. la Villa, G. Barletta and M. Novelli et al., 2009. Increased plasma carbon monoxide in patients with viral cirrhosis and hyperdynamic circulation. Am. J. Gastroenterol., 104: 891-897.
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217:   Tarquini, R., E. Masini, G. la Villa, G. Mazzoccoli and R. Mastroianni et al., 2012. Hepato-systemic gradient of carbon monoxide in cirrhosis. Eur. J. Internal Med., 23: e14-e18.
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218:   Triadafilopoulos, G., A. Taddei, P. Bechi, G. Freschi and M.N. Ringressi et al., 2011. Barrett's esophagus: Proton pump inhibitors and chemoprevention I. Annals N. Y. Acad. Sci., 1232: 93-113.
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219:   Vannacci, A., C. Marzocca, L.A. Giannini, L. Mazzetti and S. Franchi-Micheli et al., 2006. Evaluation of the effects of a novel carbon monoxide releasing molecule (CORM-3) in an in vitro model of cardiovascular inflammation. 1. Histamine in allergy, inflammation, tissue growth and repair. Inflammation Res., 55: 5-6.
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220:   Vannacci, A., C. Ravaldi, L. Giannini, C.M. Rotella, E. Masini, C. Faravelli and V. Ricca, 2006. Increased nitric oxide production in eating disorders. Neurosci. Lett., 399: 230-233.
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221:   Vannacci, A., G. Zagli, C. Marzocca, S. Pierpaoli and M.B. Passani et al., 2002. Down-regulation by cannabinoids of the immunological activation of human basophils and guinea pig mast cells. Inflamm. Res., 51: 9-10.
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222:   Vannacci, A., L. Giannini, E. Masini and P.F. Mannaioni, 2003. Cannabinoid-induced activation of ERK and AKT in mast cells may be mediated by intracellular NO production. J. Immunol., Vol. 171. .
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223:   Vannacci, A., L. Giannini, F. Fabrizi, C. Uliva and R. Mastroianni et al., 2007. Effects of the carbon monoxide releasing molecule CORM-3 in a coincubation model of rat mast cells with human neutrophils. Inflammation Res., 56: S13-S14.
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224:   Vannacci, A., L. Giannini, M.B. Passani, A. Di Felice and S. Pierpaoli et al., 2004. The endocannabinoid 2-arachidonylglycerol decreases the immunological activation of Guinea pig mast cells: Involvement of nitric oxide and eicosanoids. J. Pharmacol. Exp. Therap., 311: 256-264.
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225:   Vannacci, A., M.B. Passani, S. Pierpaoli, L. Giannini, P.F. Mannaioni and E. Masini, 2003. Nitric oxide modulates the inhibitory effect of cannabinoids on the immunological activation of guinea pig mast cells. Inflamm. Res., 52: 7-8.
226:   Vannacci, A., R. Baronti, E. Masini, C. Ravaldi and V. Ricca, 2002. Anorexia Nervosa and risk of sudden death. Am. J. Med., 112: 327-328.
227:   Vannacci, A., R. Baronti, G. Zagli, C. Marzocca and S. Pierpaoli et al., 2003. Carbon monoxide modulates the response of human basophils to FcepsilonRI stimulation through the heme oxygenase pathway. Eur. J. Pharmacol., 465: 289-297.
228:   Vizzutti, F., R.G. Romanelli, U. Arena, L. Rega and M. Brogi et al., 2007. ADMA correlates with portal pressure in patients with compensated cirrhosis. Eur. J. Clin. Invest., 37: 509-515.
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229:   Wang, Z.Q., F. Porreca, S. Cuzzocrea, K. Galen and R. Lightfoot et al., 2004. A newly identified role for superoxide in inflammatory pain. J. Pharmacol. Exp. Ther., 309: 869-878.
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230:   Ziche, M., L. Morbidelli, E. Masini, H. Granger, P. Geppetti and F. Ledda, 1993. Nitric oxide promotes DNA synthesis and cyclic GMP formation in endothelial cells from postcapillary venules. Biochem. Biophys. Res. Commun., 192: 1198-1203.
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231:   Ziche, M., L. Morbidelli, E. Masini, S. Amerini and H.J. Granger et al., 1994. Nitric oxide mediates angiogenesis In vivo and endothelial cell growth and migration In vitro promoted by substance P. J. Clin. Invest., 94: 2036-2044.
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