Dr. Graziano  Riccioni

Dr. Graziano Riccioni

Medical Professional/Doctor
University of Chieti, Italy


Highest Degree
Ph.D. in Biomedical Sciences from University of Chieti, Italy

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Area of Interest:

Biomedical Sciences
100%
Allergy
62%
Immunopathology
90%
Pharmacology
75%
Inflammation
55%

Education

2004

Ph.D.

University of Chieti, Italy

Biomedical Sciences

Selected Publications

  1. Riccioni, G., L. Speranza, M. Pesce, S. Cusenza, N. D'Orazio and M.J. Glade, 2012. Novel phytonutrient contributors to antioxidant protection against cardiovascular disease. Nutrition, 28: 605-610.
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  2. Riccioni, G., 2012. Marine carotenoids and oxidative stress. Marine Drugs, 10: 116-118.

  3. Speranza, L., S. Franceschelli, N. D'Orazio, R. Gaeta and T. Bucciarelli et al., 2011. The biological effect of pharmacological treatment on dimethylaminohydrolases (DDAH-1) and cationic amino acid transporter-1 (CAT-1) expression in patients with acute congestive heart failure. Microvasc. Res., 82: 391-396.
    CrossRef  |  Direct Link  |  

  4. Riccioni, G., V. Bucciarelli, E. Di Ilio, L. Scotti and A. Aceto et al., 2011. Recurrent atrial fibrillation in a patient with ulcerative colitis treated with azathioprine: Case report and review of the literature. Int. J. Immunopathol. Pharmacol., 24: 247-249.
    PubMed  |  

  5. Riccioni, G., N. D'Orazio, S. Franceschelli and L. Speranza, 2011. Marine carotenoids and cardiovascular risk markers. Marine Drugs, 9: 1166-1175.

  6. Riccioni, G., L. Speranza, L. Scotti, V. Bucciarelli and E. Di Ilio et al., 2011. The effect of pharmacological treatment on ADMA in patients with heart failure. Front. Biosci., 3: 1310-1314.

  7. Riccioni, G., L. Scotti, E. Di Ilio, V. Bucciarelli and E. Ballone et al., 2011. Lycopene and preclinical carotid atherosclerosis. J. Biol. Regul. Homeost. Agents, 25: 435-441.

  8. Riccioni, G., F. Cipollone, D. Santovito, L. Scotti, N. D'Orazio, A. Mezzetti and T. Bucciarelli, 2011. Effect of 2-year treatment with low-dose rosuvastatin on intima-media thickness in hypercholesterolemic subjects with asymptomatic carotid artery disease. Expert Opin. Pharmacother., 12: 2599-2604.
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  9. Riccioni, G., 2011. Ivabradine: Recent and potential applications in clinical practice. Expert Opin. Pharmacother., 12: 443-450.
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  10. Riccioni, G., 2011. Aliskiren in the treatment of hypertension and organ damage. Cardiovas. Therap., 29: 77-87.
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  11. Franceschelli, S., M. Pesce, I. Vinciguerra, A. Ferrone and G. Riccioni et al., 2011. Licocalchone-C extracted from Glycyrrhiza Glabra inhibits lipopolysaccharide-interferon-γ inflammation by improving antioxidant conditions and regulating inducible nitric oxide synthase expression. Molecules, 16: 5720-5734.
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  12. Riccioni, G., V. Bucciarelli, L. Scotti, A. Aceto, N. D'Orazio, E. Di Ilio and T. Bucciarelli, 2010. Relationship between asymmetric dimethylarginine and asymptomatic carotid atherosclerosis. J. Biol. Regul. Homeostatic Agents, 24: 351-358.

  13. Riccioni, G., N. Vitulano, B. Mancini, A. Zanasi and N. D'Orazio, 2010. One-year treatment with rosuvastatin reduces intima-media thickness in 45 hypercholesterolemic subjects with asymptomatic carotid artery disease. Pharmacology, 85: 63-67.
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  14. Riccioni, G., N. Vitulano, A. Zanasi, F. Bellocci and N. D'Orazio, 2010. Aliskiren: Beyond blood pressure reduction. Expert Opin. Invest. Drugs, 19: 1265-1274.
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  15. Riccioni, G., N. D'Orazio, L. Scotti, R. Petruzzelli and A. Latino et al., 2010. Circulating plasma antioxidants, inflammatory markers and asymptomatic carotid atherosclerosis in end-stage renal disease patients: A case control study. Int. J. Immunopathol. Pharmacol., 23: 327-334.

  16. Riccioni, G., M. Back and V. Capra, 2010. Leukotrienes and atherosclerosis. Curr. Drug Targets, 11: 882-887.
    Direct Link  |  

  17. Riccioni, G., A. Zanasi, N. Vitulano, B. Mancini and N. D'Orazio,2010 2010. Leukotrienes in atherosclerosis: New target insights and future therapy perspectives. Mediators Inflamm., Vol. 2009 10.1155/2009/737282.
    CrossRef  |  

  18. Riccioni, G., 2010. Ivabradine: From molecular basis to clinical effectiveness. Adv. Ther., 27: 160-167.
    CrossRef  |  

  19. Riccioni, G., N. Vitulano, N. D'Orazio and F. Bellocci, 2009. Aliskiren, the first approved renin inhibitor: Clinical application and safety in the treatment of hypertension. Adv. Ther., 26: 700-710.
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  20. Riccioni, G., N. Vitulano and N. D'Orazio, 2009. Ivabradine: Beyond heart rate control. Adv. Ther., 26: 12-24.
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  21. Riccioni, G., N. D'Orazio, N. Palumbo, V. Bucciarelli, E. di Ilio, L.A. Bazzano and T. Bucciarelli, 2009. Relationship between plasma antioxidant concentrations and carotid intima-media thickness: The asymptomatic carotid atherosclerotic disease in manfredonia study. Eur. J. Cardiovasc. Preven. Rehabil., 16: 351-357.
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  22. Riccioni, G., 2009. The effect of antihypertensive drugs on carotid intima media thickness: An up-to-date review. Curr. Med. Chem., 16: 988-996.
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  23. Riccioni, G., 2009. Statins and carotid intima-media thickness reduction: An up-to-date review. Curr. Med. Chem., 16: 1799-1805.
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  24. Riccioni, G., 2009. Focus on ivabradine: A new heart rate-controlling drug. Expert Rev. Cardiovasc. Ther., 7: 107-113.
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  25. Riccioni, G., 2009. Carotenoids and cardiovascular disease. Curr. Atheroscler. Rep., 11: 434-439.
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  26. Riccioni, G., V. Capra, N. D'Orazio, T. Bucciarelli and L.A. Bazzano, 2008. Leukotriene modifiers in the treatment of cardiovascular diseases. J. Leukocyte Biol., 84: 1374-1378.
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  27. Riccioni, G., T. Bucciarelli, N. D'Orazio, N. Palumbo and E. Di Ilio et al., 2008. Plasma antioxidants and asymptomatic carotid atherosclerotic disease. Ann. Nutr. Metab., 53: 86-90.
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  28. Riccioni, G., L.A. Bazzano, T. Bucciarelli, B. Mancini, E. Di Ilio and N. D'Orazio, 2008. Rosuvastatin reduces intima-media thickness in hypercholesterolemic subjects with asymptomatic carotid artery disease: The Asymptomatic Carotid Atherosclerotic Disease in Manfredonia (ACADIM) Study. Expert Opin. Pharmacother., 9: 2403-2408.
    CrossRef  |  Direct Link  |  

  29. Riccioni, G., B. Mancini, E. Di Ilio, T. Bucciarelli and N. D'Orazio, 2008. Protective effect of lycopene in cardiovascular disease. Eur. Rev. Med. Pharmacol. Sci., 12: 183-190.
    Direct Link  |  

  30. Riccioni, G. and L.A. Bazzano, 2008. Antioxidant plasma concentration and supplementation in carotid intima media thickness. Expert Rev. Cardiovasc. Ther., 6: 723-729.
    CrossRef  |  

  31. Sblendorio, V., B. Palmieri and G. Riccioni, 2007. Blood cholesterol concentration measured by CR3000: Fingerstick versus venous sampling. Int. J. Immunopathol. Pharmacol., 21: 729-733.
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  32. Riccioni, G., T. Bucciarelli, B. Mancini, F. Corradi, C. Di Ilio, P.A. Mattei and N. D'Orazio, 2007. Antioxidant vitamin supplementation in cardiovascular diseases. Ann. Clin. Lab. Sci., 37: 89-95.
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  33. Riccioni, G., T. Bucciarelli, B. Mancini, E. di Ilio and G. Palumbo et al., 2007. Compliance therapy with Anti-inflammatory antiasthmatic drugs: Inhaled corticosteroids and leukotriene receptor antagonists. Clinica Ter., 158: 363-370.
    PubMed  |  

  34. Riccioni, G., T. Bucciarelli, B. Mancini, C.D. Ilio, R.D. Vecchia and N. D'Orazio, 2007. Plasma lycopene and antioxidant vitamins in asthma: The PLAVA study. J. Asthma, 44: 429-432.
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  35. Riccioni, G., T. Bucciarelli, B. Mancini, C. di Ilio and N. D'Orazio, 2007. Antileukotriene drugs: Clinical application, effectiveness and safety. Curr. Med. Chem., 14: 1966-1977.
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  36. Riccioni, G., T. Bucciarelli, B. Mancini, C. Di Ilio, V. Capra and N. D'Orazio, 2007. The role of the antioxidant vitamin supplementation in the prevention of cardiovascular diseases. Expert Opin. Invest. Drugs, 16: 25-32.
    CrossRef  |  Direct Link  |  

  37. Riccioni, G., M. Barbara, T. Bucciarelli, C. di Ilio and N. D'Orazio, 2007. Antioxidant vitamin supplementation in asthma. Ann. Clin. Lab. Sci., 37: 96-101.
    Direct Link  |  

  38. Riccioni, G., 2007. Integrated control of hypertension, dyslipidemia and carotid atherosclerosis in the reduction of cardiovascular risk. Exp. Rev. Cardiovasc Ther., 5: 371-374.
    PubMed  |  

  39. Riccioni, G. and N. D'Orazio, 2007. Reduction of intima-media thickness in subjects with asymptomatic carotid disease: Two cases from the Asymptomatic Carotid Atherosclerosis DIsease Manfredonia Study (ACADIM Study). Clin. Terap., 158: 431-433.
    PubMed  |  

  40. Castellani, M.L., Y.B. Shaik, L.N. Shanmugham, S. Frydas and B. Madhappan et al., 2007. Role of flavonoids and vitamins in cancer. Rivista Biol., 100: 39-54.
    PubMed  |  

  41. Riccioni, G., T. Bucciarelli, C. di Ilio, F. Corradi and R. Della Vecchia et al., 2006. Is nasal polyposis a determinant of bronchial hyperresponsiveness and altered quality of life in asthmatic subjects? A case-control study. Ann. Clin. Lab. Sci., 36: 170-173.
    Direct Link  |  

  42. Riccioni, G., T. Bucciarelli, B. Mancini, C. di Ilio and N. D'Orazio, 2006. Plasma lycopene concentration is low in subjects with stable asthma. Allergy, 61: 1371-1372.
    CrossRef  |  

  43. Riccioni, G., B. Mancini, T. Bucciarelli, C. Di Ilio and N. D'Orazio, 2006. Role of anti-oxidants in the treatment of bronchial asthma. Drug Discovery Today, 3: 293-298.
    CrossRef  |  

  44. Capra, V., M. Ambrosio, G. Riccioni and G.E. Rovati, 2006. Cysteinyl-leukotriene receptor antagonists: Present situation and future opportunities. Curr. Med. Chem., 13: 3213-3226.
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  45. Riccioni, G., V. di Pietro, T. Staniscia, L. de Feudis and G. Traisci et al., 2005. Community acquired pneumonia in internal medicine: a one-year retrospective study based on pneumonia severity index. Int. J. Immunopathol. Pharmacol., 18: 575-586.
    PubMed  |  

  46. Riccioni, G., M. de Benedictis, R. Della Vecchia, C. di Ilio, M.T. Guagnano and N. D'Orazio, 2005. Prevalence and severity of the airway obstruction degree in an Italian adult population: Result of One-year observational study. Mon. Arch. Chest Dis., 63: 88-92.

  47. Riccioni, G. And N. D'Orazio, 2005. The role of selenium, zinc and antioxidant vitamin supplementation in the treatment of bronchial asthma: Adjuvant therapy or not? Exp. Opin. Invest. Drugs, 14: 1145-1155.
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  48. Frydas, S., N. Papaioannou, M. Papazahariadou, M. Hatzistilianou and E. Karagouni et al., 2005. Inhibition of MCP-1 and MIP-2 chemokines in murine trichinellosis: Effect of the Anti-inflammatory compound L-mimosine. Int. J. Immunopathol. Pharmacol., 18: 85-94.
    PubMed  |  

  49. Riccioni, G., V. Menna, M.S. Lambo, R. Della Vecchia, C. di Ilio, A. de Lorenzo and N. D'Orazio, 2004. Leptin and hypothalamus-hypophysis-thyroid axis. Clin. Terapeutica, 155: 29-31.
    PubMed  |  

  50. Riccioni, G., V. Menna, F. Filippakos, C. di Ilio and G. di Tano et al., 2004. Interaction connecting Leptin-obesity-insulin dependent diabetes mellitus. Eur. J. Inflammation, 2: 17-20.

  51. Riccioni, G., V. Menna, C. di Ilio and N. D'Orazio, 2004. Food-intake and nutrients pattern in Italian adult male subjects. Clin. Ter., 155: 283-286.
    PubMed  |  

  52. Riccioni, G., R. Della Vecchia, V. Menna, T. Staniscia, C. di Ilio, P. Conti and N. D'Orazio, 2004. Irritable bowel syndrome and bronchial hyperresponsiveness: Is there a link? Digestion, 69: 185-189.
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  53. Riccioni, G., R. Della Vecchia, V. Menna, C. Di Ilio, P. Conti and N. D'Orazio, 2004. Prevalence of bronchial asthma in patients with Endoscopically-documented esophagitis. Ann. Clin. Lab. Sci., 34: 94-98.
    PubMed  |  

  54. Riccioni, G., R. Della Vecchia, F. Romano, T. Staniscia and N. Verna et al., 2004. Interrelationship between asthma and functional bowel disease. Eur. J. Infl., 3: 125-128.

  55. Riccioni, G., R. Della Vecchia, C. di Ilio and N. D'Orazio, 2004. Effect of the two different leukotriene receptor antagonists montelukast and zafirlukast on quality of life: A 12-week randomized study. Allergy Asthma Proc., 25: 445-448.
    Direct Link  |  

  56. Riccioni, G., N. D'Orazio, C. di Ilio, V. Menna, M.T. Guagnano and R. Della Vecchia, 2004. Quality of life and clinical symptoms in asthmatic subjects. J. Asthma, 41: 85-89.
    Direct Link  |  

  57. Riccioni, G., C.D. Ilio and N. D'Orazio, 2004. An update of the leukotriene modulators for the treatment of asthma. Exp. Opin. Invest. Drugs, 13: 763-776.
    CrossRef  |  Direct Link  |  

  58. Riccioni, G., C. di Ilio, P. Conti, T.C. Theoharides and N. D'Orazio, 2004. Advances in therapy with antileukotriene drugs. Ann. Clin. Lab. Sci., 34: 379-387.
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  59. Riccioni, G., C. di Ilio and N. D'Orazio, 2004. Pharmacological treatment of airway remodeling: Inhaled corticosteroids or antileukotrienes? Ann. Clin. Lab. Sci., 34: 138-142.
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  60. Kempuraj, D., J. Donelan, S. Frydas, T. Iezzi and F. Conti et al., 2004. Interleukin-28 and 29 (IL-28 and IL-29): New cytokines with Anti-viral activities. Int. J. Immunopathol. Pharmacol., 17: 103-106.
    PubMed  |  

  61. Kempuraj, D., C. Petrarca, S. Frydas, G. Riccioni, P. Conti, S. Tete and J. Vecchiet, 2004. Rat peritoneal mast cells release regulated upon activation normal T cell expressed and secreted (RANTES) after TNF-alpha activation. J. Biol. Regulators Homeostatic Agents, 19: 130-135.
    PubMed  |  

  62. Huang, S.H., S. Frydas, P. Conti, D. Kempuraj and R.C. Barbacane et al., 2004. Interleukin-17: A revisited study. Int. J. Immunopathol. Pharmacol., 17: 1-4.
    PubMed  |  

  63. Huang, S.H., S. Frydas, D. Kempuraj, R.C. Barbacane and A. Grilli et al., 2004. Interleukin-17 and the Interleukin-17 family member network. Allergy Asthma Proc., 25: 17-21.
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  64. Frydas, S., T. Iezzi, D. Kempurai, W. Boucher and N.G. Papadoupolou et al., 2004. Human genome project and parasitic infections. Eur. J. Inflammation, 1: 1-4.

  65. Riccioni, G., S. Sensi, E. Ballone, M.T. Guagnano and R. Della Vecchia, 2003. Bronchial hyperresponsiveness, age, sex, sigarette smoke and quality of life in asthmatic subjects. Gior. Mal. Tor., 57: 116-123.

  66. Riccioni, G., R.D. Vecchia, N. D'Orazio, S. Sensi and M.T. Guagnano, 2003. Comparison of montelukast and budesonide on bronchial reactivity in subjects with Mild-moderate persistent asthma. Pulmonary Pharmacol. Ther., 16: 111-114.
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  67. Riccioni, G., R. Della Vecchia, V. Menna, M.S. Lambo, C. di Ilio, N. D'Orazio, 2003. Gli antileucotrienici nella terapia dell'asma bronchiale. Rec. Prog. Med., 94: 509-515.

  68. Riccioni, G., R. Della Vecchia, M.T. Guagnano and N. D'Orazio, 2003. Asthma of the gut: Dream or reality? Eur. J. Clin. Invest., 33: 733-734.
    CrossRef  |  PubMed  |  

  69. Riccioni, G., N. D'Orazio, V. Menna, M. Lambo, MT Guagnano and C. di Ilio, 2003. The role of leptina in nervosa anorexia. Clin. Ter., 154: 401-404.

  70. Riccioni, G., N. D'Orazio, V. Menna and A. de Lorenzo, 2003. Fat soluble vitamins and immune system: An overview. Eur. J. Infl., 2: 59-64.

  71. Riccioni, G., N. D'Orazio, R. Della Vecchia and C. di Ilio, 2003. Remodelling and inflammation in bronchial asthma. Eur. J. Infl., 1: 9-12.

  72. Riccioni, G., N. D'Orazio, C. di Ilio, R. Della Vecchia, E. Ballone, V. Menna and M.T. Guagnano, 2003. Bronchial hyperresponsiveness and quality of life in asthmatic subjects. Respiration, 70: 496-499.

  73. Riccioni, G., A. de Santis, V. Cerasa, V. Menna and C. di Ilio et al., 2003. Atherosclerotic plaque formation and risk factors. Int. J. Immunopathol. Pharmacol., 16: 25-31.
    PubMed  |  

  74. Kempurai, D., S. Frydas, K. Kandere, B. Madhappan, R. Letorneau et al., 2003. Interleukin-19 (IL-19) network revisited. Int. J. Immunopathol. Pharmacol., 16: 95-97.

  75. Huang, S.H., F. Gambi, F. Conti, G. Carratelli and C.M. Conti et al., 2003. Antiepileptic drugs lower contraceptive sex hormone and increase the risk of unplanned pregnancies in women with epilepsy: Revisited study. Int. J. Immunopathol. Pharmacol., 16: 181-183.
    PubMed  |  

  76. Guagnano, M.T., M.R. Manigrasso, E. Ballone, R. Della Vecchia and G. Riccioni et al., 2003. Association between serum leptin levels and 24-hour blood pressure in obese women. Obesity Res., 11: 549-555.
    CrossRef  |  

  77. Frydas, S., M. Papazahariadou, N. Papaioannou, M. Hatzistilianou and M. Trakatellis et al., 2003. Effect of the compound L-mimosine in an in vivo model of chronic granuloma formation induced by potassium permanganate (KMNO4). Int. J. Immunopathol. Pharmacol., 16: 99-104.
    PubMed  |  

  78. Frydas, S., M. Hatzistilianou, B. Madhappan, N. D'Orazio, G. Riccioni, P. Conti and D. Kempurai, 2003. Chemokines and parasites. Int. J. Immunopathol. Pharmacol., 16: 221-224.

  79. Riccioni, G., R. Della Vecchia, M. Castronuovo, V. di Pietro and R. Spoltore et al., 2002. Bronchial hyperresponsiveness in adults with seasonal and perennial rhinitis: Is there a link for asthma and rhinitis? Int. J. Immunopathol. Pharmacol., 15: 69-74.
    PubMed  |  

  80. Riccioni, G., N. D'Orazio, C. di Ilio, R. Della Vecchia and A. de Lorenzo, 2002. Effectiveness and safety of montelukast versus budesonide at various doses on bronchial reactivity in subjects with mild persistent asthma. Clin. Ter., 153: 317-321.
    PubMed  |  

  81. Riccioni, G., F. Santilli, N. D'Orazio, S. Sensi and R. Spoltore et al., 2002. The role of antileukotrienes in the treatment of asthma. Int. J. Immunopathol. Pharmacol., 15: 171-182.
    PubMed  |  

  82. Riccioni, G., E. Ballone, N. D'Orazio, S. Sensi and M. di Nicola et al., 2002. Effectiveness of montelukast versus budesonide on quality of life and bronchial reactivity in subjects with Mild-persistent asthma. Int. J. Immunopathol. Pharmacol., 15: 149-155.
    PubMed  |  

  83. D'Orazio, N., C. Ficoneri, G. Riccioni, P. Conti, T.C. Theoharides and M.R. Bollea, 2002. Conjugated linoleic acid: A functional food? Int. J. Immunopathol. Pharmacol., 16: 215-220.
    Direct Link  |  

  84. Riccioni, G., F. di Stefano, M. de Benedictis, N. Verna and E. Cavallucci et al., 2001. Seasonal variability of Non-specific bronchial responsiveness in asthmatic patients with allergy to house dust mites. Allergy Asthma Proc., 22: 5-9.
    CrossRef  |  Direct Link  |  

  85. Guagnano, M.T., E. Ballone, V. Colagrande, R. Della Vecchia and M.R. Manigrasso et al., 2001. Large waist circumference and risk of hypertension. Int. J. Obesity Related Metab. Disorders: J. Int. Assoc. Study Obesity, 25: 1360-1364.
    CrossRef  |  Direct Link  |  

  86. Di Gioacchino, M., E. Cavallucci, F. di Stefano, F. Paolini and S. Ramondo et al., 2001. Effect of natural allergen exposure on Non-specific bronchial reactivity in asthmatic farmers. Sci. Total Environ., 270: 43-48.
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  87. Riccioni, G., M. Castronuovo, M. de Benedictis, V. Pace-Palitti and M. di Gioacchino et al., 2000. Zafirlukast versus budesonide on bronchial reactivity in subjects with Mild-persistent asthma. Int. J. Immunopathol. Pharmacol., 14: 87-92.
    Direct Link  |  

  88. Di Gioacchino, M., E. Cavallucci, F. di Stefano, N. Verna and S. Ramondo et al., 2000. Influence of total IgE and seasonal increase of eosinophil cationic protein on bronchial hyperreactivity in asthmatic Grass-sensitized farmers. Allergy, 55: 1030-1034.
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