Hi, I am Adriana Georgescu, My LiveDNA is 40.5950
 
   
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Dr. Adriana Georgescu
 
Highest Degree: Ph.D. in Natural Sciences from Institute of Cellular Biology and Pathology Nicolae Simionescu, Romaia
 
Institute: Institute of Cellular Biology and Pathology 'Nicolae Simionescu', Romania
 
Area of Interest: Biomedical Sciences
  •   Atherosclerosis
  •   Diabetes
  •   Biomarkers
  •   Regenerative Medicine
 
URL: http://livedna.org/40.5950
 
My SELECTED Publications
1:   Alexandru, N. and A. Georgescu, 2013. Circulating microparticles and microRNAs as players in atherosclerosis. World J. Hematol., 2: 16-19.
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2:   Alexandru, N., A. Georgescu, M. Amuzescu, C. Zamfir, A. Badila and D. Popov, 2011. Platelet reactivity in chronic venous insufficiency. Clin. Lab., 57: 527-534.
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3:   Alexandru, N., D. Popov and A. Georgescu, 2010. Intraplatelet oxidative/nitrative stress: Inductors, consequences and control. Trends Cardiovasc. Med., 20: 232-238.
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4:   Alexandru, N., D. Popov and A. Georgescu, 2012. Platelet dysfunction in vascular pathologies and how can it be treated. Thromb. Res., 129: 116-126.
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5:   Alexandru, N., D. Popov, E. Dragan, E. Andrei and A. Georgescu, 2011. Platelet activation in hypertension associated with hypercholesterolemia: Effects of irbesartan. J. Thromb. Haemost., 9: 173-184.
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6:   Alexandru, N., D. Popov, E. Dragan, E. Andrei and A. Georgescu, 2013. Circulating endothelial progenitor cell and platelet microparticle impact on platelet activation in hypertension associated with hypercholesterolemia. PloS One, Vol. 8. 10.1371/journal.pone.0052058.
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7:   Alexandru, N., E. Badila and A. Georgescu, 2014. The role of endothelial progenitor cells in the cardiovascular disease pathogenesis. J. Stem Cells Res. Rev. Rep., Vol. 1, No. 2. .
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8:   Andrei, E., N. Alexandru, E. Dragan and A. Georgescu, 2014. Flow cytometric analysis of circulating microparticles and endothelial progenitor cells in plasma; a research tool for atherosclerosis and therapy. Exp. Clin. Cardiol., 20: 1554-1563.
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9:   Badila, E., A.M. Daraban, S. Ghiorghe, A. Georgescu, N. Alexandru, D. Bartos and C. Tirziu, 2014. Rethinking cardiovascular therapy-the effect of irbesartan on circulating microparticles and endothelial progenitor cells in patients with hypertension and dyslipidemia. Farmacia, 62: 93-106.
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10:   Chahed, S., A.S. Leroyer, M. Benzerroug, D. Gaucher and A. Georgescu et al., 2010. Increased vitreous shedding of microparticles in proliferative diabetic retinopathy stimulates endothelial proliferation. Diabetes, 59: 694-701.
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11:   Costache, G., A. Georgescu, M. Cenuse, D. Popov and M. Simionescu, 1998. Alterations of resistance vessels and capillaries in hyperlipemic-hyperglycemic hamsters. Proceedings of the 70th EAS Congress, September 6-9, 1998, Geneva -.
12:   Costache, G., D. Popov, A. Georgescu, M. Cenuse, V.V. Jinga and M. Simionescu, 2000. The effects of simultaneous hyperlipemia-hyperglycemia on the resistance arteries, myocardium and kidney glomeruli. J. Submicroscop. Cytol. Pathol., 32: 47-58.
PubMed  |  
13:   Costache, G., M. Hasu, D. Popov and A. Georgescu, 1997. The use of the myograph technique for the investigation of the vascular reactivity: A review. Curr. Problems Tech. Cell. Mol. Biol., 2: 38-43.
14:   Costahe, G., D. Popov, A. Georgescu and M. Simionescu, 1999. Functional-structural alterations of the resistance arteries in experimental hyperlipemia or hypergliycemia. Proc. Roman. Acad. Ser. B., 1: 33-37.
15:   Georgescu, A. and D. Popov, 1998. Influence of experimental diabetes on the cells of vascular wall. Studii si Cercetari de Biochimie, 41: 107-117.
16:   Georgescu, A. and D. Popov, 2000. Age-dependent accumulation of advanced glycation endproducts is accelerated in combined hyperlipidemia and hyperglycemia, a process attenuated by L-arginine. J. Am. Aging Assoc., 23: 33-40.
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17:   Georgescu, A. and D. Popov, 2001. Vascular reactivity of the resistance arteries to potassium in combined hyperlipemia-hyperglycemia. Proc. Roman. Acad. Ser. B., 1: 111-117.
18:   Georgescu, A. and D. Popov, 2003. The contractile response of the mesenteric resistance arteries to prostaglandin F; effects of simultaneous hyperlipemia-diabetes. Fundam. Clin. Pharmacol., 17: 683-689.
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19:   Georgescu, A. and F. Antohe, 2011. Editor of the International Monograph from Vascular Cell Biology to Cardiovascular Medicine. In: Research Signpost Transworld Research Network, De Gortari, P. (Ed.). Kerala, India.
20:   Georgescu, A., 2011. Vascular dysfunction in diabetes: The endothelial progenitor cells as new therapeutic strategy. World J. Diabetes, 2: 92-97.
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21:   Georgescu, A., 2014. Cardiovascular Dysfunction: New Biomarkers and Therapies. Scholars' Press, Saarbrucken, Germany, ISBN-13: 978-3-639-71643-6, Pages: 180.
22:   Georgescu, A., D. Popov and G. Costache, 1998. Vascular reactivity of resistance arteries of hyperlipemic-hyperglycemic hamsters in the presence of vasoconstrictor agents. Curr. Problems Tech. Cell. Mol. Biol., 3: 124-129.
23:   Georgescu, A., D. Popov and L. Vladimirescu, 2001. Effect of blocking the intercellular communication junctions on the contractile response of the resistance arteries. Curr. Problems Tech. Cell. Mol. Biol., 6: 85-90.
24:   Georgescu, A., D. Popov and M. Hasu, 1997. Quantitative fluorimetric analysis of advanced glycosylation end products in mesenteric arteries and lens crystallin of hyperlipemic and simultaneously hyperlipemic and hyperglycemic hamsters. Curr. Problems Tech. Cell. Mol. Biol., 2: 65-68.
25:   Georgescu, A., D. Popov and M. Simionescu, 2001. Mechanisms of impeded brady kinininduced vasodilation in experimental hyperlipemia-hyperglycemia: Contribution of nitric oxide and Ca2+ activated K+ channels. Fundam. Clin. Pharmacol., 15: 335-342.
26:   Georgescu, A., D. Popov, A. Constantin, M. Nemecz, N. Alexandru, D. Cochior and A. Tudor, 2011. Dysfunction of human subcutaneous fat arterioles in obesity alone or obesity associated with Type 2 diabetes. Clin. Sci., 120: 463-472.
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27:   Georgescu, A., D. Popov, E. Dragan, E. Dragomir and E. Badila, 2007. Protective effects of nebivolol and reversal of endothelial dysfunction in diabetes associated with hypertension. Eur. J. Pharmacol., 570: 149-158.
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28:   Georgescu, A., D. Popov, E. Dragomir, E. Dragan and M. Simionescu, 2006. Nebivolol protects and reverses endothelial dysfunction in diabetes associated with hypertension: Molecular mechanisms involved. Proceedings of the 24th Conference of the European Society for Microcirculation, August 30-September 2, 2006, Amsterdam, Netherlands, pp: 81-81.
29:   Georgescu, A., D. Popov, M. Capraru and M. Simionescu, 2003. Enoxaparin: A low molecular weight heparin, restores the altered vascular reactivity of resistance arteries in aged and aged-diabetic hamsters. Vasc. Pharmacol., 40: 167-174.
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30:   Georgescu, A., D. Popov, N. Alexandru, A. Tudor and M. Simionescu, 2007. Structural and functional assessment of small arteries in obesity and type II diabetes. Proceedings of the 76th Congress of the European Atherosclerosis Society , Volume 8, June 10-13, 2007, Helsinki, Finland, pp: 229-229.
31:   Georgescu, A., F. Pluteanu, M.L. Flonta, E. Badila, M. Dorobantu and D. Popov, 2005. The cellular mechanisms involved in the vasodilator effect of nebivolol on the renal artery. Eur. J. Pharmacol., 508: 159-166.
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32:   Georgescu, A., F. Pluteanu, M.L. Flonta, E. Badila, M. Dorobantu and D. Popov, 2007. Nebivolol induces a hyperpolarizing effect on smooth muscle cells in the mouse renal artery by activation of beta-2-adrenoceptors. Pharmacology, 81: 110-117.
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33:   Georgescu, A., F. Safciuc and E. Constantinescu, 2006. The effect of aging on the vasomotor function of rat basilar artery. Proc. Roman. Acad. Ser. B., 1: 13-17.
34:   Georgescu, A., G. Costache, D. Popov and M. Simionescu, 1998. The abnormal responses to PGF2 and potassium of the mesenteric resistance arteries in hyperlipemic- hyperglycemic hamsters. Proceedings of the 3rd European Research Conference on Blood Pressure and Cardiovascular Disease, October 16-18, 1998, Netherlands -.
35:   Georgescu, A., N. Alexandru and D. Popov, 2011. Ongoing Data on Vascular Endothelial Cell Dysfunction: An Update. In: From Vascular Cell Biology to Cardiovascular Medicine, Georgescu, A. and F. Antohe (Eds.). Kerala, India, ISBN: 978-81-7895-503-2, pp: 125-141.
36:   Georgescu, A., N. Alexandru, A. Constantinescu, I. Titorencu and D. Popov, 2011. The promise of EPC-based therapies on vascular dysfunction in diabetes. Eur. J. Pharmacol., 669: 1-6.
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37:   Georgescu, A., N. Alexandru, D. Popov, M. Amuzescu and E. Andrei et al., 2009. Chronic venous insufficiency is associated with elevated level of circulating microparticles. J. Thromb. Haemost., 7: 1566-1575.
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38:   Georgescu, A., N. Alexandru, E. Andrei, I. Titorencu and E. Dragan et al., 2012. Circulating microparticles and endothelial progenitor cells in atherosclerosis: pharmacological effects of irbesartan. J. Thromb. Haemost., 10: 680-691.
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39:   Georgescu, A., N. Alexandru, E. Constantinescu and D. Popov, 2006. Effect of gap junction uncoupler heptanol on resistance arteries reactivity in experimental models of diabetes, hyperlipemia and hyperlipemia-diabetes. Vasc. Pharmacol., 44: 513-518.
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40:   Georgescu, A., N. Alexandru, M. Nemecz, I. Titorencu and D. Popov, 2011. Enoxaparin reduces adrenergic contraction of resistance arterioles in aging and in aging associated with diabetes via engagement of MAP kinase pathway. Blood Coagul. Fibrinol., 22: 310-316.
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41:   Georgescu, A., N. Alexandru, M. Nemecz, I. Titorencu and D. Popov, 2013. Irbesartan administration therapeutically influences circulating endothelial progenitor cell and microparticle mobilization by involvement of pro-inflammatory cytokines. Eur. J. Pharmacol., 711: 27-35.
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42:   Lupu, M., M. Khalil, E. Andrei, F. Iordache and K. Pfannkuche et al., 2011. Integration properties of Wharton's jelly-derived novel mesenchymal stem cells into ventricular slices of murine hearts. Cell. Physiol. Biochem., 28: 63-76.
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43:   Nemecz, M., D. Popov and A. Georgescu, 2010. Phosphorylation/dephosphorylation signaling events in the aorta of streptozotocin-injected Golden Syrian Hamsters. Ann. RSCB, 25: 28-34.
44:   Popov, D., G. Costache and A. Georgescu, 2001. Altered Vascular Reactivity of the Resistance Arteries: Lessons from the Hyperlipemic-Hyperglycemic Hamster Model. In: New Insights into Experimental Diabetes, Cheta, D.M. (Ed.). The Publishing House of the Romanian Academy, Rome, ISBN: 9789732708712, pp: 211-222.
45:   Popov, D., G. Costache, A. Georgescu and M. Enache, 2002. Beneficial effects of L-arginine supplementation in experimental hyperlipemia-hyperglycemia in the hamster. Cell Tissue Res., 308: 109-120.
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46:   Popov, D., G. Costache, A. Georgescu, M. Cenuse and M. Simionescu, 1998. In hyperlipemichyperglycemic hamsters the micro and macroangiopathic alterations are accompanied by modifications that may lead to an increased blood pressure. Proceedings of the 3rd European Research Conference on Blood Pressure and Cardiovascular Disease, October 16-18, 1998, Netherlands -.
47:   Popov, D., G. Costache, A. Georgescu, M. Enache and M. Simionescu, 2000. Mechanisms of the impeded relaxation of the resistance arteries in hyperlipemia-hyperglycemia. Proceedings of the 5th Annual Meeting of the European Council for Blood Pressure and Cardiovascular Research, October 13-15, 2000, Noordwijkerhout, Netherlands -.
48:   Popov, D., M. Nemecz, M. Dumitrescu, A. Georgescu and F.D. Bohmer, 2009. Long-term high glucose concentration influences Akt, ERK1/2 and PTP1B protein expression in human aortic smooth muscle cells. Biochem. Biophys. Res. Commun., 388: 51-55.
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49:   Radu, D.L., A. Georgescu, C. Stavaru, A. Carale and D. Popov, 2004. Double transgenic mice with type 1 diabetes mellitus develop somatic, metabolic and vascular disorders. J. Cell. Mol. Med., 8: 349-358.
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50:   Radu, L., C. Stavaru, A. Georgescu, D. Popov and C. Coman, 2002. Transgenic mouse model of type 1 diabetes. Proc. Jpn. Soc. Immunol., 32: 11-16.
51:   Schneider, M., A. Georgescu, C. Bidmon, M. Tutsch, E.H. Fleischmann, D. Popov and M. Pischetsrieder, 2006. Detection of DNA-bound advanced glycation end‐products by immunoaffinity chromatography coupled to HPLC-diode array detection. Mol. Nutr. Food Res., 50: 424-429.
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52:   Stancu, C.S., A. Georgescu, L. Toma, G.M. Sanda and A.V. Sima, 2012. Glycated low density lipoproteins alter vascular reactivity in hyperlipidemic hyperglycemic hamsters. Ann. Roman. Soc. Cell Biol., 17: 9-15.
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53:   Titorencu, I., M.G. Albu, F. Anton, A. Georgescu and V.V. Jinga, 2012. Collagen-dexamethasone and collagen-D3 scaffolds for bone tissue engineering. Mol. Cryst. Liquid Cryst., 555: 208-217.
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54:   Ton, B.H.T., Q. Chen, G. Gaina, C. Tucureanu and A. Georgescu et al., 2013. Activation profile of dorsal root ganglia Iba-1 (+) macrophages varies with the type of lesion in rats. Acta Histochemica, 115: 840-850.
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55:   Voinea, M., A. Georgescu, A. Manea, E. Dragomir, I. Manduteanu, D. Popov and M. Simionescu, 2004. Superoxide dismutase entrapped-liposomes restore the impaired endothelium-dependent relaxation of resistance arteries in experimental diabetes. Eur. J. Pharmacol., 484: 111-118.
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