Dr. Justine  Rudner

Dr. Justine Rudner

Researcher
University of Tuebingen, Germany


Highest Degree
Ph.D. in Cell Biology from University of Tuebingen, Germany

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Area of Interest:

Molecular Sciences
100%
Cell Biology
62%
Oncology
90%
Radiation Therapy
75%
Cell Signaling
55%

Education

2002

Ph.D.

University of Tuebingen, Germany

Cell Biology

1998

M.Sc.

University of Bochum, Germany

Biochemistry

Selected Publications

  1. Rudner, J., S.J. Elsaesser, V. Jendrossek and S.M. Huber, 2011. Anti-apoptotic Bcl-2 fails to form efficient complexes with pro-apoptotic Bak to protect from Celecoxib-induced apoptosis. Biochem. Pharmacol., 81: 32-42.
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  2. Zoppoli, G., M. Cea, D. Soncini, F. Fruscione and J. Rudner et al., 2010. Potent synergistic interaction between the Nampt inhibitor APO866 and the apoptosis activator TRAIL in human leukemia cells. Exp. Hematol., 38: 979-988.
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  3. Rudner, J., S.J. Elsaesser, A.C. Muller, C. Belka and V. Jendrossek, 2010. Differential effects of anti-apoptotic Bcl-2 family members Mcl-1, Bcl-2, and Bcl-xL on Celecoxib-induced apoptosis. Biochem. Pharmacol., 79: 10-20.
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  4. Rudner, J., C.E. Ruiner, R. Handrick, H. Eibl, C. Belka and V. Jendrossek, 2010. The Akt-inhibitor Erufosine induces apoptotic cell death in prostate cancer cells and increases the short term effects of ionizing radiation. Radiat. Oncol., 5: 108-119.
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  5. Heise, N., D. Palme, M. Misovic, S. Koka and J. Rudner et al., 2010. Non-selective cation channel-mediated Ca2+-entry and activation of Ca2+/calmodulin-dependent kinase II contribute to G2/M cell cycle arrest and survival of irradiated leukemia cells. Cell. Physiol. Biochem., 26: 597-608.
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  6. Rudner, J., A.C. Mueller, N. Matzner, S.M. Huber, R. Handrick, C. Belka and V. Jendrossek, 2009. The additional loss of Bak and not the lack of the protein tyrosine kinase p56/Lck in one JCaM1.6 subclone caused pronounced apoptosis resistance in response to stimuli of the intrinsic pathway. Apoptosis, 14: 711-720.
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  7. Muller, A.C., R. Handrick, S.J. Elsaesser, J. Rudner and G. Henke et al., 2008. Importance of Bak for celecoxib-induced apoptosis. Biochem. Pharmacol., 76: 1082-1096.
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  8. Rudner, J., V. Jendrossek, K. Lauber, P.T. Daniel, S. Wesselborg and C. Belka, 2005. Type I and type II reactions in TRAIL-induced apoptosis-results from dose-response studies. Oncogene, 24: 130-140.
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  9. Handrick, R., J. Rudner, I. Muller, H. Eibl, C. Belka and V. Jendrossek, 2005. Bcl-2 mediated inhibition of erucylphosphocholine-induced apoptosis depends on its subcellular localisation. Biochem. Pharmacol., 70: 837-850.
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