Dr. Justine  Rudner

Dr. Justine Rudner

University of Tuebingen, Germany

Highest Degree
Ph.D. in Cell Biology from University of Tuebingen, Germany

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Area of Interest:

Molecular Sciences
Cell Biology
Radiation Therapy
Cell Signaling




University of Tuebingen, Germany

Cell Biology



University of Bochum, Germany


Selected Publications

  1. Rudner, J., S.J. Elsaesser, V. Jendrossek and S.M. Huber, 2011. Anti-apoptotic Bcl-2 fails to form efficient complexes with pro-apoptotic Bak to protect from Celecoxib-induced apoptosis. Biochem. Pharmacol., 81: 32-42.
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  2. Zoppoli, G., M. Cea, D. Soncini, F. Fruscione and J. Rudner et al., 2010. Potent synergistic interaction between the Nampt inhibitor APO866 and the apoptosis activator TRAIL in human leukemia cells. Exp. Hematol., 38: 979-988.
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  3. Rudner, J., S.J. Elsaesser, A.C. Muller, C. Belka and V. Jendrossek, 2010. Differential effects of anti-apoptotic Bcl-2 family members Mcl-1, Bcl-2, and Bcl-xL on Celecoxib-induced apoptosis. Biochem. Pharmacol., 79: 10-20.
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  4. Rudner, J., C.E. Ruiner, R. Handrick, H. Eibl, C. Belka and V. Jendrossek, 2010. The Akt-inhibitor Erufosine induces apoptotic cell death in prostate cancer cells and increases the short term effects of ionizing radiation. Radiat. Oncol., 5: 108-119.
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  5. Heise, N., D. Palme, M. Misovic, S. Koka and J. Rudner et al., 2010. Non-selective cation channel-mediated Ca2+-entry and activation of Ca2+/calmodulin-dependent kinase II contribute to G2/M cell cycle arrest and survival of irradiated leukemia cells. Cell. Physiol. Biochem., 26: 597-608.
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  6. Rudner, J., A.C. Mueller, N. Matzner, S.M. Huber, R. Handrick, C. Belka and V. Jendrossek, 2009. The additional loss of Bak and not the lack of the protein tyrosine kinase p56/Lck in one JCaM1.6 subclone caused pronounced apoptosis resistance in response to stimuli of the intrinsic pathway. Apoptosis, 14: 711-720.
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  7. Muller, A.C., R. Handrick, S.J. Elsaesser, J. Rudner and G. Henke et al., 2008. Importance of Bak for celecoxib-induced apoptosis. Biochem. Pharmacol., 76: 1082-1096.
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  8. Rudner, J., V. Jendrossek, K. Lauber, P.T. Daniel, S. Wesselborg and C. Belka, 2005. Type I and type II reactions in TRAIL-induced apoptosis-results from dose-response studies. Oncogene, 24: 130-140.
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  9. Handrick, R., J. Rudner, I. Muller, H. Eibl, C. Belka and V. Jendrossek, 2005. Bcl-2 mediated inhibition of erucylphosphocholine-induced apoptosis depends on its subcellular localisation. Biochem. Pharmacol., 70: 837-850.
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