Area of Interest:

Pharmacology and Toxicology

100%

Drug Metabolism

62%

Cytochrome P450

90%

Pharmacogenetics

75%

Drug-Herb Interaction

55%

Research Publications in Numbers

Books
0

Chapters
0

Articles
6

Abstracts
0

Selected Publications

Pan, Y., B.A. Abd-Rashid, Z. Ismail, R. Ismail and J.W. Mak et al., 2011. In vitro modulatory effects of Andrographis paniculata, Centella asiatica and Orthosiphon stamineus on cytochrome P450 2C19 (CYP2C19). J. Ethnopharmacol., 133: 881-887.
CrossRef | PubMed | Direct Link |
Tiong, K.H., B.C. Yiap, E.L. Tan, R. Ismail and C.E. Ong, 2010. Functional characterization of cytochrome P450 2A6 allelic variants CYP2A6*15, CYP2A6*16, CYP2A6*21, and CYP2A6*22. Drug Metabolism Disposition, 38: 745-751.
CrossRef | PubMed | Direct Link |
Tiong, K.H., B.C. Yiap, E.L. Tan, R. Ismail and C.E. Ong, 2010. In vitro modulation of naturally occurring flavonoids on cytochrome P450 2A6 (CYP2A6) activity. Xenobiotica, 40: 458-466.
CrossRef | PubMed | Direct Link |
Pan, Y., B.A. Abd-Rashid, Z. Ismail, R. Ismail and J.W. Mak et al., 2010. In vitro modulatory effects on three major human cytochrome P450 enzymes by multiple active constituents and extracts of Centella asiatica. J. Ethnopharmacol., 130: 275-283.
CrossRef | PubMed | Direct Link |
Singh, R., J.G. Ting, Y. Pan, L.K. Teh, R. Ismail and C.E. Ong, 2008. Functional role of Ile264 in CYP2C8: Mutations affect haem incorporation and catalytic activity. Drug Metabolism Pharmacokinetics, 23: 165-174.
CrossRef | PubMed | Direct Link |
Ong, C.E., Y. Pan, K.H. Tiong, B.C. Yiap, E.L. Tan, P. Pook and J.W. Mak, 2008. Pharmacogenomics in drug therapy and interaction: The role of cytochrome P450. Int. J. Sci. Med. Educ., 2: S6-S10.
Direct Link |