Dr. Alexander C.K. Lai
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Dr. Alexander C.K. Lai

Assistant Professor
Kentucky State University, Kentucky


Highest Degree
Ph.D. in Biomedical Sciences from City University of New York, USA

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Area of Interest:

Biomedical Sciences
100%
Molecular Virology
62%
Vaccine Technology
90%
Bioinformatic
75%
Immunology
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Su, S., G. Wong, W. Shi, J. Liu and A.C.K. Lai et al., 2016. Epidemiology, genetic recombination and pathogenesis of coronaviruses. Trends Microbiol., 24: 490-502.
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  2. Zhou, P., J. Ma, A.C.K. Lai, G. Gray, S. Su and S. Li, 2015. Avian influenza A(H7N9) virus and mixed live poultry-animal markets in Guangdong Province: A perfect storm in the making? Emerg. Microbes Infect., Vol. 4. 10.1038/emi.2015.63.
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  3. Su, S., J. Tian, M. Hong, P. Zhou and G. Lu et al., 2015. Global and quantitative proteomic analysis of dogs infected by avian-like H3N2 canine influenza virus. Front. Microbiol., Vol. 6. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382988/.
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  4. Su, S., L. Wang, X. Fu, S. He and M. Hong et al., 2014. Equine influenza A (H3N8) virus infection in cats. Emerg. Infect. Dis., 20: 2087-2090.
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  5. Su, S., J. Chen, P. Zhou, A.C.K. Lai and C. Ke et al., 2013. Detection of antibodies against avian influenza virus subtypes H7 and H9 among veterinarians in Guangdong province, China. J. Clin. Microbiol., 51: 4272-4274.
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  6. Lai, A.C.K., W.L. Wu, S.Y. Lau, Y. Guan and H. Chen, 2012. Two-dimensional antigenic dendrogram and phylogenetic tree of avian influenza virus H5N1. FEMS Immunol. Med. Microbiol., 64: 205-211.
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  7. Wang, P., W. Song, B.W.Y. Mok, P. Zhao and K. Qin et al., 2009. Nuclear Factor 90, negatively regulates influenza virus replication by interacting with viral nucleoprotein. J. Virol., 83: 7850-7861.
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  8. Cheng, P., C.S. Lau, A.C.K. Lai, E. Ho and P. Leung et al., 2009. A novel reovirus isolated from a patient with acute respiratory disease. J. Clin. Virol., 45: 79-80.
  9. Lai, A.C.K., K.M. Rogers, A. Glaser, L. Tudor and T. Chambers, 2004. Alternate circulation of recent equine-2 influenza viruses (H3N8) from two distinct lineages in the United States. Virus Res., 100: 159-164.
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  10. Divanovic, S. and A.C.K. Lai, 2004. Cytokine induction in human cord blood lymphocytes after pulsing with UV-inactivated influenza viruses. Immun. Lett., 94: 201-207.
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  11. Sengupta, S., K. Onodera, A. Lai and U. Melcher, 2003. Molecular detection and identification of influenza viruses by oligonucleotide microarray hybridization. J. Clin. Microbiol., 41: 4542-4550.
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  12. Lai, A.C.K., T.M. Chambers, P.S. Morley, D. Haines, H. Townsend and M. Barrandeguy, 2001. Diverged evolution of recent equine-2 influenza (H3N8) virus in the Western Hemisphere. Arch. Virol., 146: 1063-1074.
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  13. Lai, A.C.K. and A.M. McPhillips, 1999. Isolation of avian influenza viruses in Central Oklahoma. J. Oklahoma State Med. Assoc., 92: 565-567.
  14. Wu, P.C., J.W. Fang, C.L. Lai, S.S. Lau, C.K. Lo, A.C.K. Lai and J.Y. Lau, 1996. Hepatic expression of hepatitis B virus genome in chronic hepatitis B virus infection. Am. J. Clin. Pathol., 105: 87-95.
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  15. Daly, J.M., A.C.K. Lai, M.M. Binns, T.M. Chambers, M. Barrandeguy and J.A. Mumford, 1996. Antigenic and genetic evolution of equine H3N8 influenza A viruses. J. Gen. Virol., 77: 661-671.
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  16. Lai, A.C.K. and T.M. Chambers, 1995. Rapid protocol for sequencing RNA virus using *Taq* version 2.0 DNA polymerase. BioTechniques, 19: 704-706.
  17. Chambers, T.M., R.E. Holland and A.C.K. Lai, 1995. Equine influenza: Current veterinary perspectives, Part II. Equine Pract., 17: 26-30.
  18. Chambers, T.M., R.E. Holland and A.C.K. Lai, 1995. Equine influenza: Current veterinary perspectives, Part I. Equine Pract., 17: 19-23.
  19. Lai, A.C.K., Y.P. Lin, D.G. Powell, K.F. Shortridge, R.G. Webster, J. Daly and T.M. Chambers, 1994. Genetic and antigenic analysis of the influenza virus responsible for the 1992 Hong Kong equine influenza epizootic. Virology, 204: 673-679.
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  20. Chang, P.Y., A.C.K. Lai and B.G.T. Pogo, 1992. Attenuated deletion mutant of vaccinia virus IHD-W recovered virulence by reinsertion of a terminal restriction fragment. Microb. Pathogenesis, 13: 49-59.
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  21. Pogo, B.G.T., A.C.K. Lai, M.E. Joesten, M.E. Royston and D. Holloway, 1991. Changes in cell gene expression in human leukemic cells persistently infected with vaccinia virus. Virus Res., 19: 131-138.
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  22. Lai, A.C.K. and Y. Chu, 1991. A rapid method for screening vaccinia virus recombinants. BioTechniques, 10: 564-565.
    PubMed  |  
  23. Lai, A.C.K. and B.G.T. Pogo, 1989. Characterization of vaccinia virus deletion mutants isolated from persistently infected Friend erythroleukemia cells. Virus Res., 12: 239-250.
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  24. Lai, A.C.K. and B.G.T. Pogo, 1989. Attenuated deletion mutants of vaccinia virus lacking the vaccinia growth factor are defective in replication in vivo. Microb. Pathogenesis, 6: 219-226.
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  25. Pogo, B.G.T., A.C.K. Lai, G. Holland and C. Friend, 1988. Differences in the susceptibility of human blood cell lines to vaccinia virus. Intervirology, 29: 11-20.
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  26. Moran, T.M., M. Monestier, A.C.K. Lai, G. Norton and M.A. Reale et al., 1987. Characterization of variable-region genes and shared crossreactive idiotypes of antibodies specific for antigens of various influenza viruses. Viral Immunol., 1: 1-12.
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