Dr. Sundar Rao Koyyalamudi

Dr. Sundar Rao Koyyalamudi

Research Scientist
The Children Hospital at Westmead, Sydney


Highest Degree
Ph.D. in Organic Chemistry from Roorkee University, India

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Area of Interest:

Chemistry
100%
Organic Chemistry
62%
Medicinal Plants/Mushrooms
90%
Phytochemistry
75%
Natural Products
55%

Education

1986

Ph.D.

Roorkee University, India

Organic Chemistry

Selected Publications

  1. Zhang, L., K.S. Rao, S.C. Jeong, N. Reddy, T. Bailey and T. Longvah, 2013. Immunomodulatory activities of polysaccharides isolated from Taxillus chinensis and Uncaria rhyncophylla. Carbohydr. Polym., 98: 1458-1465.
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  2. Zhang, L., A.S. Ravipati, S.R. Koyyalamudi, S.C. Jeong and N. Reddy et al., 2013. Anti-fungal and anti-bacterial activities of ethanol extracts of selected traditional Chinese medicinal herbs. Asian Pac. J. Trop. Med., 6: 673-681.
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  3. Ravipati, A.S., L. Zhang, S.R. Koyyalamudi, S.C. Jeong and N. Reddy, 2013. Anti-proliferative activities of selected Chinese medicinal herbs against human cancer cell lines. Phytopharmacology, 4: 206-219.
    Direct Link  |  

  4. Koyyalamudi, S.R., S.C. Jeong, S. Manavalan, B. Vysetti, G. Pang, 2013. Micronutrient mineral content of the fruiting bodies of Australian cultivated Agaricus bisporus white button mushrooms. J. Food Compos. Anal., 31: 109-114.
    CrossRef  |  

  5. Jeong, S.C., S.R. Koyyalamudi, J. Hughes, C. Khoo, T. Bailey, J.P. Park, C.H. Song, 2013. Modulation of cytokine production and complement activity by biopolymers extracted from medicinal plants. Phytopharmacology, 4: 19-30.

  6. Jeong, S.C., S.R. Koyyalamudi, J. Hughes, C. Khoo and T. Bailey et al., 2013. Antioxidant and immunomodulating activities of exo-and endopolysaccharide fractions from submerged mycelia cultures of culinary-medicinal mushrooms. Int. J. Med. Mushrooms, 15: 251-266.
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  7. De Pedro, N., M.R. Chica, J. Cantizani, B. Cautain and F. Vicente et al., 2013. Antiproliferative and apoptotic potential of Chinese medicinal plants against MCF-7 (luminal A), HCC1954 (HER2+) and Hs578t breast cancer cells. Phytopharmacology, 4: 1-14.

  8. Zhang, L., S.R. Koyyalamudi, S.C. Jeong, N. Reddy, P.T. Smith, R. Ananthan and T. Longvah, 2012. Antioxidant and immunomodulatory activities of polysaccharides from the roots of Sanguisorba officinalis. Int. J. Biol. Macromol., 51: 1057-1062.
    Direct Link  |  

  9. Ravipati, A.S., L. Zang, S.R. Koyyalamudi, N. Reddy and J. Bartlett et al., 2012. Antioxidant and anti-inflammatory activities of selected Chinese medicinal plants and their relation with antioxidant content. BMC Complementary Altern. Med., 12: 173-178.
    CrossRef  |  

  10. Jeong, S.C., S.R. Koyyalamudi, G. Pang, Y.T. Jeong and C.H. Song, 2012. Macrophage immunostimulating and anti-tumor activities of polysaccharides isolated from Agaricus bisporus white button mushrooms. J. Med. Foods, 15: 58-65.

  11. Jeong, S.C., S.R. Koyyalamudi and G. Pang, 2012. Dietary intake of Agaricus bisporus white button mushroom accelerates salivary immunoglobulin a secretion in healthy volunteers. Nutrition, 28: 527-531.
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  12. Diaz, P., S.C. Jeong, S. Lee, C. Khoo and S.R. Koyyalamudi, 2012. Antioxidant and anti-inflammatory activities of selected medicinal plants and fungi containing phenolic and flavonoid compounds. Chinese Med. J., 7: 26-30.
    CrossRef  |  

  13. Zhang, L., A.S. Ravipati, S.R. Koyyalamudi, S.C. Jeong and N. Reddy et al., 2011. Antioxidant and anti-inflammatory activities of selected medicinal plants containing phenolic and flavonoid compounds. J. Agric. Food Chem., 59: 12361-12367.
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  14. Koyyalamudi, S.R., S.C. Jeong, G. Pang, A. Teal and T. Biggs, 2011. High concentration of vitamin D2 is produced in white button mushrooms (Agaricus bisporus) treated with pulsed UV-C light. J. Food Comp. Anal., 24: 976-979.

  15. Jeong, S.C., Y.T. Jeong, B.K. Yang, R. Islam and S.R. Koyyalamudi et al., 2010. White button mushroom (Agaricus bisporus) lowers blood glucose and cholesterol levels in diabetic and hypercholesterolemic rats. Nut. Res., 30: 49-56.
    Direct Link  |  

  16. Koyyalamudi, S.R., S.C. Jeong, K.Y. Cho and G. Pang, 2009. Vitamin B12 is the active corrinoid produced in cultivated white button mushrooms (Agaricus bisporus). J. Agric. Food Chem., 57: 6327-6333.
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  17. Koyyalamudi, S.R., S.C. Jeong, C.H. Song, K.Y. Cho and G. Pang, 2009. Vitamin D12 formation and bioavailability from Agaricus bisporus button mushrooms treated with ultraviolet irradiation. J. Agric. Food Chem., 57: 3351-3355.
    CrossRef  |  PubMed  |  

  18. Jeong, S.C., B.K. Yang, Y.T. Jeong, K.S. Rao and C.H. Song, 2007. Isolation and characterization of biopolymers extracted from the bark of Acanthopanax sessiliflorus and their anticomplement activity. J. Microbiol. Biotechn., 17: 21-28.
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  19. Jeong, S.C., M.A Wilson, Y. Cho, S.R. Koyyalamudi and C.H. Song, 2006. Macrophage stimulating activity of biopolymers extracted from fruiting bodies of Coriolus versicolor. J. Med. Food, 9: 175-181.

  20. Ito, C., M. Itoigawa, Y. Miyamoto, S. Onoda and K.S. Rao et al., 2003. Polyprenylated benzophenones from Garcinia assigu and their potential cancer chemopreventive activities. J. Nat. Prod., 66: 206-209.
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  21. Prakash, A.S., H.P. Tran, C. Peng, S.R. Koyalamudi and C.T. Dameron, 2000. Kinetics of DNA alkylation, depurination and hydrolysis of anti diol epoxide of benzo(a)pyrene and the effect of cadmium on DNA alkylation. Chem. Biol. Int., 125: 133-150.
    Direct Link  |  

  22. Ito, C., Y. Kondo, K. Sundar Rao, H. Tokuda, H. Nishino and H. Furukawa, 1999. Chemical constituents of Glycosmis pentaphylla. Isolation of a novel naphthoquinone and a new acridone alkaloid. Chem. Pharm. Bull., 47: 1579-1581.
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  23. Ito, C., M. Itoigawa, Y. Miyamoto, K. Sundar Rao and J. Takayasu et al., 1999. A new biflavonoid from Calophyllum panciflorum with antitumor-promoting activity. J. Nat. Prod., 62: 1668-1671.
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  24. Bermejo, A., M.A. Blazquez, K. Sundar Rao and D. Cortes, 1999. Styryl-lactones from the stem bark of Goniothalamus arvensis. Phytochem. Anal., 10: 127-131.
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  25. Prakash, A.S., K.S. Rao and C.T. Dameron, 1998. Cadmium inhibits BPDE alkylation of DNA in the major groove but not in the minor groove. Biochem. Biophys. Res. Commun., 244: 198-203.
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  26. Ito, C., M. Itoigawa, H. Furukawa, K. Sundar Rao and F. Enjo et al., 1998. Xanthones as inhibitors of Epstein-Barr virus activation. Cancer Lett., 132: 113-117.
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  27. Bermejo, A., M.A. Blazquez, K. Sundar Rao and D. Cortes, 1998. Styryl-pyrones from Goniothalamus arvensis. Phytochemistry, 47: 1375-1380.
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  28. Kawazoe, K., N. Shimogai, Y. Takaishi, K. Sundar Rao and Y. Imakura, 1997. Four stilbenes from Salacia lehmbachii. Phytochemistry, 44: 1569-1573.
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  29. Ito, C., Y. Miyamoto, M. Nakayama, Y. Kawai, K. Sundar Rao and H. Furukawa, 1997. A Novel depsidone and some new xanthones from Garcinia species. Chem. Pharma. Bull., 45: 1403-1413.
    Direct Link  |  

  30. De Vries, D.J., K. Sundar Rao and R.H. Willis, 1997. Application of a radioreceptor assay to the screening and characterisation of compounds from marine organisms with activity at the phorbol ester binding site of protein kinase C. Toxicology, 35: 347-354.
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  31. Sundar, R.K., 1996. Antibacterial activity of some medicinal plants of Papua New Guinea. Int. J. Pharmacognosy, 34: 223-225.
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  32. Rao, S. and R.T. Erasmus, 1996. A pilot study on plasma fatty acids in poorly controlled non insulin dependent (Type 2) Melanesian diabetics. Central Afr. J. Med., 42: 295-297.
    PubMed  |  Direct Link  |  

  33. Ito, C., Y. Miyamoto, K. Sundar Rao and H. Furukawa, 1996. A novel dibenzofuran and two new xanthones from Calophyllum panciflorum. Chem. Pharmac. Bull., 44: 441-443.
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  34. Hansel, M., K. Sundar Rao, W. Benlo, K. Alam, T. Rali, M. Huber and I. Burrows, 1996. Distribution of fatty acids and minerals in Papua New Guinean sea urchins. Fish. Technol., 32: 50-52.

  35. Gonzalez, M.C., M.A. Sentandreu, K. Sundar Rao, M.C. Zafra-Polo and D. Cortes, 1996. Prenylated benzopyran derivatives from two Polyalthia species. Phytochemistry, 43: 1361-1364.
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  36. Jones, G.P., K. Sundar Rao, D.J. Tucker, B. Richardson, A. Barnes and D.E. Rivett, 1995. Antimicrobial activity of santalbic acid from the oil of Santalum acuminatum (Quandong). Int. J. Pharmacol., 33: 120-123.
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  37. Gonzalez, M.C., A. Serrano, M.C. Zafra-Polo, D. Cortes and K. Sundar Rao, 1995. Polycerasoidin and Polycerasoidol: Two new prenylated benzopyrane derivatives from Polyalthia cersoides. J. Nat. Prod., 58: 1278-1284.

  38. Bermejo, A., P. Protais, M.A. Blazquez, K. Sundar Rao, M.C. Zafra-Polo and D. Cortes, 1995. Dopaminergic isoquinoline alkaloids from roots of Xylopia papuana. Nat. Prod. Lett., 6: 57-62.
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  39. Bermejo, A., M.J. Lora, M.A. Blazquez, K. Sundar Rao, D. Cortes and M.C. Zafra-Polo, 1995. (+)- Goniotharvensin, a novel styryl-lactone from the stem bark of Goniothalamus arvensis. Nat. Product Lett., 7: 117-122.
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  40. Yuwai, K.E., K.S. Rao, K. Singh, T. Tanaka and Y. Ueno, 1994. Occurrence of nivalenol, deoxynivalenol and zearalenone in imported cereals in Papua, New Guinea. Nat. Toxins, 2: 19-21.
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  41. Alam, K., T. Agua, R. Taie, K. Sundar Rao, P.H. Petsul, J. Kola, J. Tamate and I. Burrows, 1994. Elemental and Fatty acid compositions of seaweeds and seagrass from Papua New Guinea. Sci. New Guinea, 20: 23-26.

  42. Agua, T., H. Maven, T. Taie, K. Alam, K.S. Rao, I. Burrows, M.D. Huber and T. Rali, 1994. Preliminary screening of seaweeds, seagrass and lemongrass oil from Papua New Guinea for antimicrobial and antifungal activity. Int. J. Pharmacognosy, 32: 396-399.
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  43. Sundarrao, K., I. Burrows, M. Kuduk, Y.D. Yi, M.H. Chung, N.J. Suh and I.M. Chang, 1993. Preliminary screening of antibacterial and antitumor activities of Papua New Guinean native medicinal plants. Pharm. Biol., 31: 3-6.
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  44. Sino, D. and K.S. Rao, 1993. The distribution of fatty acids in the seed oils of the compositae, liliaceae, ranunculaceae and sapindaceae families. J. Sci. Food Agric., 62: 99-100.
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  45. Hansel, M. K. Sundar Rao, T. Matsuoka, T. Rali, I. Burrows and M.E. Huber, 1993. The Distribution of fatty acids in flesh and liver of papua new Guinean fish. Comparat. Biochem. Physiol. Part B: Comparat. Biochem., 106: 655-658.
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  46. Fried, B., K.S. Rao, J. Sherma and J.E. Huffman, 1993. Fatty acid composition of Goniobasis virginica, Physa sp. and Viviparus malleatus (Mollusca: Gastropoda) from Lake Musconetcong, New Jersey. Biochem. Systemat. Ecol., 21: 809-812.
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  47. Fried, B., J. Sherma, K. Sundar Rao and R.G. Ackman, 1993. Fatty acid composition of Biomphalaria glabrata (Gastropoda: Planorbidae) experimentally infected with the intramolluscan stages of Echinostoma caproni (Trematoda). Comparative Biochem. Physiol., 104: 595-598.

  48. Fried, B., K.S. Rao, J. Sherma and J.E. Huffman, 1993. Fatty acid composition of Echinostoma trivolvis (Trematoda) rediae and adults and of the digestive gland-gonad complex of Helisoma trivolvis (Gastropoda) infected with the intramolluscan stages of this echinostome. Parasitol. Res., 79: 471-474.
    PubMed  |  Direct Link  |  

  49. Sundarrao, K., J. Tinkerame, C. Kaluwin, K. Singh and T. Matsuoka, 1992. Fatty acid and mineral composition of shellfish (Gelonia papua). Fishery Technol., 29: 144-146.
    Direct Link  |  

  50. Sundarrao, K., G.P. Jones, D.E. Rivett and D.J. Tucker, 1992. Occurence of santalbic acid in Exocarpus sparteus and Exocarpus aphyllus seed oils. Oleagineux, 47: 91-92.
    Direct Link  |  

  51. Sundar Rao, K., G.P. Jones, D.E. Rivett and D.J. Tucker, 1992. Fatty acid composition of newer seed oils. Lipid/Fett, 94: 37-38.
    CrossRef  |  

  52. Rao, K.S. and D. Sino, 1992. Fatty acid composition of 20 lesser‐known Western Australian seed oils. J. Sci. Food Agric., 58: 585-587.
    CrossRef  |  

  53. Pue, A.G., W. Rivu, K. Sundarrao, C. Kaluwin and K. Singh, 1992. Preliminary studies on changes in coconut water during maturation of the fruit. Sci. New Guinea, 18: 81-84.
    Direct Link  |  

  54. Fried, B., K.S. Rao and J. Sherma, 1992. Fatty acid composition of two strains of Helisoma trivolvis (Gastropoda). Biochem. Syst. Ecol., 20: 553-557.
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  55. Fried, B., K.S. Rao and J. Sherma, 1992. Fatty acid composition of Biomphalaria glabrata (gastropoda: Planorbidae) fed hen's egg yolk versus leaf lettuce. Comparative Biochem. Physiol. Part A: Physiol., 101: 351-352.
    CrossRef  |  

  56. Yuwai, K.E., K.S. Rao, C. Kaluwin, G.P. Jones and D.E. Rivett, 1991. Chemical composition of Momordica charantia L. fruits. J. Agric. Food Chem., 39: 1762-1763.
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  57. Sundarrao, K., J. Tinkerame, C. Kaluwin, K. Singh and T. Matsuoka, 1991. Lipid content, fatty acid and mineral composition of mud crabs ( Scylla serrata) from Papua New Guinea. J. Food Composition Anal., 4: 276-280.
    CrossRef  |  

  58. Sundarrao, K., A.G. Pue, C. Kaluwin, K. Singh and V.V.D. Jayasuriya, 1991. Changes in oil, protein, ash, fatty acid and mineral composition during maturation of coconut kernel variety. Malayan Dwarf X Rennell Tall. Sci. New Guinea (Papua New Guinea), 17: 59-62.
    Direct Link  |  

  59. Sundar Rao, K., Y. Jeho, S. Nanjoo and C. IL-Moo, 1991. Assay of potential antimutagenicity of Papua New Guinean herbal drugs by using SOS chromotest (E.coli PQ 37). Korean J. Toxicol., 7: 151-155.

  60. Sundar Rao, K., G.P. Jones, D.E. Rivett and D.J. Tucker, 1991. A new source of alpha eleostearic acid: Ricinocarpus bowmanii and Ricinocarpus tuberculatus seed oils. J. Sci. Food Agric., 57: 427-429.
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  61. Rao, K.S., 1991. Cyclopropenoid fatty acids of six seed oils from Malvaceae. J. Am. Oil Chem. Soc., 68: 518-519.
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  62. Rao, K.S., 1991. Characteristics and fatty acid composition of Brachychiton species seeds and the oils (Sterculiaceae). J. Agric. Food Chem., 39: 881-882.
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  63. Pue, A.G., K. Sundarrao, C. Kaluwin and K. Singh, 1991. Lipid classes and fatty acid composition of copra meal. Sci. New Guinea, 17: 73-76.
    Direct Link  |  

  64. Pue, A.G., C. Kaluwin, K. Sundar Rao, K. Singh and I. Burrows, 1991. Aflatoxins in Papua New Guinea copra and copra meal. Sci. New Guinea, 17: 147-152.

  65. Sundar Rao, K., G.P. Jones, D.E. Rivett and D.J. Tucker, 1990. Occurrence of cis-monoenoic fatty acid in two seed oils. Econ. Bot., 44: 529-530.

  66. Rao, K.S., R. Dominic, K. Singh, C. Kaluwin, D.E. Rivett and G.P. Jones, 1990. Lipid, fatty acid, amino acid and mineral compositions of five edible plant leaves. J. Agric. Food Chem., 38: 2137-2139.
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  67. Sundar Rao, K., G.P. Jones, D.E. Rivett and D.J. Tucker, 1989. Fatty acid and amino acid compositions of Brachychiton discolor, Brachychiton diversifoliu and Brachychiton acerifolius seeds. J. Agric. Food Chem., 37: 916-917.
    CrossRef  |  

  68. Rao, K.S., G.P. Jones, D.E. Rivett and D.J. Tucker, 1989. Cyclopropene fatty acids of six seed oils from Malvaceae. J. Am. Oil Chem. Soc., 66: 360-361.
    CrossRef  |  

  69. Rao, K.S. and G. Lakshminarayana, 1988. Lipid class and fatty acid compositions of edible tissues of Peucedanum graveolens, Mentha arvensis and Colocasia esculenta plants. J. Agric. Food Chem., 36: 475-478.
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  70. Lakshminarayana, G., K.S. Rao, M.H. Klttur and C.S. Mahajanshetty, 1988. Occurrence of punicic acid inTrichosanthes bracteata andTrichosanthes nervifolia seed oils. J. Am. Oil Chem. Soc., 65: 347-348.
    CrossRef  |  

  71. Lakshminarayana, G., K.S. Rao, A.J. Pantulu and D.R. Gupta, 1988. Surface and internal lipids of Calotropis gigantea L. leaves. Lipid/Fett, 90: 65-68.
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  72. Sundar Rao, K. and G. Lakshminarayana, 1987. Characteristics and composition of six newer seeds and the oils. Lipid/Fett, 89: 324-326.
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  73. LakshmiNarayana, G., K. SundarRao, A.J. Pantulu and D.R. Gupta, 1987. Lipid class and fatty acid composition of surface and internal lipids of lotus (Nelumbo nucifera) leaves. J. Oil Technol. Assoc. India, 19: 35-37.
    Direct Link  |  

  74. Lakshmi Narayana, G., K. Sundar Rao, B.S. Narasinga Rao and S.N. Murthy, 1987. Amino acid compositions of some lesser known oilseeds. J. Oil Technol. Assoc. India, 19: 42-43.
    Direct Link  |  

  75. Rao, K.S. and G. Lakshminarayana, 1985. Fatty acid compositions of seed oils of sevenhibiscus species of malvaceae. J. Am. Oil Chem. Soc., 62: 714-715.
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  76. Rao, K.S. and G. Lakshminarayana, 1984. Characteristics and composition of six Malvaceae seeds and the oils. J. Am. Oil Chem. Soc., 61: 1345-1346.
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  77. Lakshminarayana, G., A.J. Pantulu and K.S. Rao, 1984. Lipid class and fatty acid compositions of young Amaranthus gangeticus L. leaves. J. Agric. Food Chem., 32: 1361-1363.
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  78. Arayana, G.L., K.S. Rao, A.J. Pantulu and G. Thyagarajan, 1984. Composition of lipids in roots, stalks, leaves and flowers of Eichhornia crassipes (Mart.) Solms. Aquatic Bot., 20: 219-227.
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  79. Sundar Rao, K., A.J. Pntulu and G. Lakshminarayana, 1983. Analysis of Calotropis gigantia, Acacia caesis and Abelmoschus ficulneus seeds. J. Am. Oil Chem. Soc., 60: 1259-1261.
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