Dr. Takuji Machida
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Dr. Takuji Machida

Associate professor
Hokkaido University,Japan

Highest Degree
Ph.D. in Pharmacology from Hokkaido University, Japan

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Area of Interest:

Pharmacology and Toxicology
100%
Hypertension
62%
Cellular Pharmacology
90%
Fatty Acid Profile
75%
Protein Expression
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Machida, T., Y. Takano, K. Iizuka, M. Machida and M. Hirafuji, 2017. Methotrexate causes acute hyperplasia of enterochromaffin cells containing substance P in the intestinal mucosa of rats. J. Pharmacol. Sci., 133: 190-193.
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  2. Machida, T., K. Iizuka and M. Hirafuji, 2017. [Analysis of vascular smooth muscle cell response to mechanical stress induced by pulsatile pressure-loading apparatus]. Folia Pharmacologica Japonica, 150: 195-200, (In Japanese).
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  3. Machida, T., A. Onoguchi, K. Iizuka, S. Ishibashi, M. Yutani and M. Hirafuji, 2017. Effect of docosahexaenoic acid on voltage-independent Ca2+ entry pathways in cultured vascular smooth muscle cells stimulated with 5-hydroxytryptamine. Biol. Pharm. Bull., 40: 916-921.
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  4. Machida, T., R. Matamura, K. Iizuka and M. Hirafuji, 2016. Cellular function and signaling pathways of vascular smooth muscle cells modulated by sphingosine 1-phosphate. J. Pharmacol. Sci., 132: 211-217.
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  5. Machida, T., 2016. Analysis of vascular cell response to hypertension induced by pressure loading and its application as a tool for exploring pharmacological modes of action. Yakugaku Zasshi, 136: 1485-1490.
    CrossRef  |  PubMed  |  Direct Link  |  
  6. Machida, M., Y. Miyamura, T. Machida, K. Koyama, K. Iizuka and M. Hirafuji, 2015. Administration of olanzapine as an antiemetic agent changes glucose homeostasis in cisplatin-treated rats. Biol. Pharm. Bull., 38: 587-593.
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  7. Takano, Y., T. Machida, Y. Obara, M. Hirano and S. Kudo et al., 2014. Methotrexate causes a change in intestinal 5-hydroxytryptamine metabolism in rats. Eur. J. Pharmacol., 740: 496-503.
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  8. Machida, T., T. Hatanaka, A. Onoguchi, K. Iizuka and M. Hirafuji, 2014. Comparison of fatty acid-binding protein expression in vascular smooth muscle cells from stroke-prone spontaneously hypertensive and Wistar Kyoto rats. Pharmacologia, 5: 12-18.
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  9. Machida, T., K. Iizuka, K. Shinohara, N. Hatakeyama, K. Nakano, Y. Kubo and M. Hirafuji, 2014. Pressure stress reduces inducible NO synthase expression by interleukin-1β stimulation in cultured rat vascular smooth muscle cells. Eur. J. Pharmacol., 731: 44-49.
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  10. Iizuka, K., T. Machida and M. Hirafuji, 2014. [Hope for novel oral anticoagulants and related problems]. Folia Pharmacologica Japonica, 143: 47-47, (In Japanese).
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  11. Iizuka, K., T. Machida and M. Hirafuji, 2014. Skeletal muscle is an endocrine organ. J. Pharmacol. Sci., 125: 125-131.
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  12. Iizuka, K., T. Machida and M. Hirafuji, 2014. Extracellular MCT4 is a possible indicator for skeletal muscle MHC fiber type change. Ann. Clin. Lab. Sci., 44: 272-276.
    PubMed  |  Direct Link  |  
  13. Fujii, K., T. Machida, K. Iizuka and M. Hirafuji, 2014. Sphingosine 1-phosphate increases an intracellular Ca2+ concentration via S1P3 receptor in cultured vascular smooth muscle cells. J. Pharm. Pharmacol., 66: 802-810.
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  14. Machida, T., K. Iizuka and M. Hirafuji, 2013. 5-Hydroxytryptamine and its receptors in systemic vascular walls. Biol. Pharm. Bull., 36: 1416-1419.
    PubMed  |  Direct Link  |