Dr. Choon-Gon Jang
My Social Links

Dr. Choon-Gon Jang

Research Scientist
Scripps Research Institute, USA

Highest Degree
Ph.D. in Pharmacology from Chungbuk National University, South Korea

Share this Profile

Area of Interest:

Pharmacology and Toxicology
100%
Neuropharmacology
62%
Pharmaceutical Analysis
90%
Natural Product
75%
Pharmacology
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
320
Abstracts
23

Selected Publications

  1. Nguyen, T.L., Y.H. Tian, I.J. You, S.Y. Lee and C.G. Jang, 2011. Modafinil-induced conditioned place preference via dopaminergic system in mice. Synapse, 65: 733-741.
    CrossRef  |  PubMed  |  Direct Link  |  
  2. Kwon, S.H., H.K. Lee, J.A. Kim, S.I. Hong and S.Y. Kim et al., 2011. Neuroprotective effects of Eucommia ulmoides Oliv. Bark on amyloid beta25-35-induced learning and memory impairments in mice. Neurosci. Lett., 487: 123-127.
    CrossRef  |  PubMed  |  Direct Link  |  
  3. Bae, J.W., C.I. Choi, J.H. Lee, C.G. Jang, M.W. Chung and S.Y. Lee, 2011. Effects of UDP-glucuronosyltransferase polymorphisms on the pharmacokinetics of ezetimibe in healthy subjects. Eur. J. Clin. Pharmacol., 67: 39-45.
    CrossRef  |  PubMed  |  Direct Link  |  
  4. Bae, J.W., C.I. Choi, C.G. Jang and S.Y. Lee, 2011. Effects of CYP2C9*1/*13 on the pharmacokinetics and pharmacodynamics of meloxicam. Br. J. Clin. Pharmacol., 71: 550-555.
    CrossRef  |  PubMed  |  Direct Link  |  
  5. Bae, J.W., C.G. Jang and S.Y. Lee, 2011. Effects of clopidogrel on the pharmacokinetics of sibutramine and its active metabolites. J. Clin. Pharmacol., 51: 1704-1711.
    CrossRef  |  PubMed  |  Direct Link  |  
  6. Yoo, J.H., H.K. Lee, H.C. Kim, S.Y. Lee and C.G. Jang, 2010. GABAA receptors mediate the attenuating effects of a 5-HT3 receptor antagonist on methamphetamine-induced behavioral sensitization in mice. Synapse, 64: 274-279.
    CrossRef  |  PubMed  |  Direct Link  |  
  7. Tian, Y.H., S.Y. Lee, H.C. Kim and C.G. Jang, 2010. Repeated methamphetamine treatment increases expression of TRPV1 mRNA in the frontal cortex but not in the striatum or hippocampus of mice. Neurosci. Lett., 472: 61-64.
    CrossRef  |  PubMed  |  Direct Link  |  
  8. Tian, Y.H., J.H. Baek, S.Y. Lee and C.G. Jang, 2010. Prenatal and postnatal exposure to bisphenol A induces anxiolytic behaviors and cognitive deficits in mice. Synapse, 64: 432-439.
    CrossRef  |  PubMed  |  Direct Link  |  
  9. Nguyen, T.L., Y.S. Nam, S.Y. Lee, H.C. Kim and C.G. Jang, 2010. Effects of capsazepine, a transient receptor potential vanilloid type 1 antagonist, on morphine-induced antinociception, tolerance and dependence in mice. Br. J. Anaesth, 105: 668-674.
    CrossRef  |  PubMed  |  Direct Link  |  
  10. Nguyen, T.L., I.J. You, S. Oh, C.H. Yang, S.Y. Lee, C.G. Jang, 2010. Assessment of the rewarding effects of dimenhydrinate using the conditioned place preference paradigm in mice. Neurosci. Lett., 471: 38-42.
    CrossRef  |  PubMed  |  Direct Link  |  
  11. Kwon, S.H., H.K. Lee, J.A. Kim, S.I. Hong and H.C. Kim et al., 2010. Neuroprotective effects of chlorogenic acid on scopolamine-induced amnesia via anti-acetylcholinesterase and anti-oxidative activities in mice. Eur. J. Pharmacol., 649: 210-217.
    CrossRef  |  PubMed  |  Direct Link  |  
  12. Bae, J.W., M.J. Kim, C.G. Jang and S.Y. Lee, 2010. Protective effects of heme oxygenase-1 against MPP+-induced cytotoxicity in PC-12 cells. Neurol. Sci., 31: 307-313.
    CrossRef  |  PubMed  |  Direct Link  |  
  13. Bae, J.W., C.S. Myung, C.I. Choi, S.M. Moon, C.G. Jang nad S.Y. Lee, 2010. HPLC assay method for ceftibuten in plasma and its application to pharmacokinetic study. J. Anal. Chem., 65: 1261-1265.
    CrossRef  |  Direct Link  |  
  14. Shin, E.J., C.G. Jang, G. Bing, D.H. Park and C.H. Oh et al., 2009. Prodynorphin gene deficiency potentiates nalbuphine-induced behavioral sensitization and withdrawal syndrome in mice. Drug Alcohol. Depend., 104: 175-184.
    CrossRef  |  PubMed  |  Direct Link  |  
  15. Moon, E., Y. Her, J.B. Lee, J.H. Park and E.H. Lee et al., 2009. The multi-herbal medicine Gongjin-dan enhances memory and learning tasks via NGF regulation. Neurosci. Lett., 466: 114-119.
    CrossRef  |  PubMed  |  Direct Link  |  
  16. Kwon, S.H., H.C. Kim, S.Y. Lee and C.G. Jang, 2009. Loganin improves learning and memory impairments induced by scopolamine in mice. Eur. J. Pharmacol., 619: 44-49.
    CrossRef  |  PubMed  |  Direct Link  |  
  17. Jin, C.H., E.J. Shin, J.B. Park, C.G. Jang and Z. Li et al., 2009. Fustin flavonoid attenuates beta-amyloid (1-42)-induced learning impairment. J. Neurosci. Res., 87: 3658-3670.
    CrossRef  |  PubMed  |  Direct Link  |  
  18. Bae, J.W., N.T. Kim, C.I. Choi, M.J. Kim, C.G. Jang and S.Y. Lee, 2009. HPLC analysis of plasma glipizide and its application to pharmacokinetic study. J. Liquid Chromatogr. Related Technol., 32: 1969-1977.
    CrossRef  |  Direct Link  |  
  19. Bae, J.W., J.H. Kim, C.I. Choi, M.J. Kim and H.J. Kim et al., 2009. Effect of CYP2C9*3 allele on the pharmacokinetics of naproxen in Korean subjects. Arch. Pharm. Res., 32: 269-273.
    CrossRef  |  PubMed  |  Direct Link  |  
  20. Yoo, J.H., Y.S. Nam, S.Y. Lee and C.G. Jang, 2008. Dopamine neurotransmission is involved in the attenuating effects of 5-HT3 receptor antagonist MDL 72222 on acute methamphetamine-induced locomotor hyperactivity in mice. Synapse, 62: 8-13.
    CrossRef  |  PubMed  |  Direct Link  |  
  21. Yang, M.H., S. Kim, M.S. Jung, J.H. Shim and N.K. Ryu et al., 2008. Proteomic analysis of methamphetamine-induced reinforcement processes within the mesolimbic dopamine system. Addict. Biol., 13: 287-294.
    CrossRef  |  PubMed  |  Direct Link  |  
  22. Tian, Y.H., K.W. Lee, I.J. You, S.Y. Lee and C.G. Jang, 2008. 7-Nitroindazole, nitric oxide synthase inhibitor, attenuates physical dependence on butorphanol in rat. Synapse, 62: 582-589.
    CrossRef  |  PubMed  |  Direct Link  |  
  23. Myung, C.S., J.W. Bae, Y.S. Park, M.J. Kim and C.I. Choi et al., 2008. Analytical HPLC method validation of amiloride and its pharmacokinetic study in humans. J. Liquid Chromatogr. Related Technol., 31: 2455-2466.
    CrossRef  |  Direct Link  |  
  24. Lee, K.W., Y.H. Tian, I.J. You, S.H. Kwon and R.R. Ha et al., 2008. Blockade of M1 muscarinic acetylcholine receptors modulates the methamphetamine-induced psychomotor stimulant effect. Neuroscience, 153: 1235-1244.
    CrossRef  |  PubMed  |  Direct Link  |  
  25. Kwon, S.H., R.R. Ha, S.Y. Lee and C.G. Jang, 2008. Involvement of pCREB expression in inhibitory effects of Coptis japonica on morphine-induced psychological dependence. Biomol. Ther., 16: 113-117.
    Direct Link  |  
  26. Yu, H.S., S.Y. Lee and C.G. Jang, 2007. Involvement of 5-HT1A and GABAA receptors in the anxiolytic-like effects of Cinnamomum cassia in mice. Pharmacol. Biochem. Behav., 87: 164-170.
    CrossRef  |  PubMed  |  Direct Link  |  
  27. Yoon, B.H., J.W. Jung, J.J. Lee, Y.W. Cho and C.G. Jang et al., 2007. Anxiolytic-like effects of sinapic acid in mice. Life Sci., 81: 234-240.
    CrossRef  |  PubMed  |  Direct Link  |  
  28. Shin, E.J., J.H. Jeong, H.J. Kim, C.G. Jang and K. Yamada et al., 2007. Exposure to Extremely low frequency magnetic fields enhances locomotor activity via activation of dopamine d1-like receptors in mice. Pharmacol. Sci., 105: 367-371.
    CrossRef  |  PubMed  |  Direct Link  |  
  29. Lee, B.H., J.H. Lee, S.M. Lee, S.M. Jeong and I.S. Yoon et al., 2007. Identification of ginsenoside interaction sites in 5-HT3A receptors. Neuropharmacology, 52: 1139-1150.
    CrossRef  |  PubMed  |  Direct Link  |  
  30. Kim, J.H., S.Y. Kim, S.Y. Lee and C.G. Jang, 2007. Antidepressant-like effects of Albizzia julibrissin in mice: Involvement of the 5-HT1A receptor system. Pharmacol. Biochem. Behav., 87: 41-47.
    CrossRef  |  PubMed  |  Direct Link  |  
  31. Bae, J.W., M.J. Kim, Y.S. Park, C.S. Myung, C.G. Jang and S.Y. Lee, 2007. Considerable interindividual variation in the pharmacokinetics of tolperisone HCl. Int. J. Clin. Pharmacol. Ther., 45: 110-113.
    PubMed  |  
  32. Bae, J.W., M.J. Kim, C.G. Jang and S.Y. Lee, 2007. Determination of meloxicam in human plasma using a HPLC method with UV detection and its application to a pharmacokinetic study. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 859: 69-73.
    CrossRef  |  PubMed  |  Direct Link  |