Dr. Grace Lai-Hung Wong

Dr. Grace Lai-Hung Wong

Associate Professor
The Chinese University of Hong Kong, Hong Kong


Highest Degree
M.D. in Medicine from The Chinese University of Hong Kong, Hong Kong

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Area of Interest:

Medicine
100%
Hepatology
62%
Gastroenterology
90%
Alimentary Pharmacology and Therapeutics
75%
Antiviral Therapy
55%

Education

2010

M.D.

The Chinese University of Hong Kong, Hong Kong

Medicine

Selected Publications

  1. Wong, V.W., G.L.H. Wong, A.M. Chim, T.F. Cheng and S.W. Cheung et al., 2014. Targeted hepatitis C screening among ex-injection drug users in the community. J. Gastroenterol. Hepatol., 29: 116-120.
    CrossRef  |  PubMed  |  Direct Link  |  

  2. Wong, G.L., H.L. Chan, P.C. Choi, A.W. Chan and Z. Yu et al., 2014. Non-invasive algorithm of enhanced liver fibrosis and liver stiffness measurement with transient elastography for advanced liver fibrosis in chronic hepatitis B. Aliment. Pharmacol. Ther., 39: 197-208.
    CrossRef  |  PubMed  |  

  3. Wong, V.W.S., G.L.H. Wong and F.K.L. Chan, 2013. Liver stiffness measurement: Simplicity is prerequisite for reliability. Gastroenterology, 144: 243-244.
    CrossRef  |  Direct Link  |  

  4. Wong, V.W., R.S. Chan, G.L.H. Wong, B.H. Cheung and W.C. Chu et al., 2013. Community-Based lifestyle modification programme for non-alcoholic fatty liver disease: A randomized controlled trial. J. Hepatol., 59: 536-542.
    CrossRef  |  PubMed  |  Direct Link  |  

  5. Wong, V.W., G.L.H. Wong, A.W. Chan, W.C. Chu and P.C. Choi et al., 2013. Treatment of nonalcoholic steatohepatitis with Phyllanthus urinaria: A randomized trial. J. Gastroenterol. Hepatol., 28 : 57-62.
    CrossRef  |  PubMed  |  Direct Link  |  

  6. Wong, V.W., G.L.H. Wong, A.M. Chim, W.C. Chu, D.K. Yeung, K.C. Li and H.L. Chan, 2013. Treatment of nonalcoholic steatohepatitis with probiotics. A proof-of-concept study. Ann. Hepatol., 12: 256-262.
    PubMed  |  

  7. Wong, V.W., C.H. Tse, T.T. Lam, G.L.H. Wong and A.M. Chim et al., 2013. Molecular characterization of the fecal microbiota in patients with nonalcoholic steatohepatitis: A longitudinal study. PLoS One, Vol. 8. 10.1371/journal.pone.0062885.
    CrossRef  |  PubMed  |  

  8. Wong, J.S., G.L.H. Wong, A.W. Chan, W.V. Wong and Y.S. Cheung et al., 2013. Liver stiffness measurement by transient elastography as a predictor on posthepatectomy outcomes. Ann. Surg., 257: 922-928.
    CrossRef  |  PubMed  |  

  9. Wong, G.L.H., H.L. Chan, K.K. Yiu, J.W. Lai and V.K. Chan et al., 2013. Meta-Analysis: The association of hepatitis B virus genotypes and hepatocellular carcinoma. Aliment. Pharmacol. Ther., 37: 517-526.
    CrossRef  |  PubMed  |  Direct Link  |  

  10. Wong, G.L.H., C.N. Chong and V.W.S. Wong, 2013. Tertiary prevention of HBV-related HCC in Asia. Curr. Hepatitis Rep., 12: 157-164.
    CrossRef  |  Direct Link  |  

  11. Wong, G.L.H., 2013. Who will have the best response to entecavir? J. Gastroenterol. Hepatol., 28: 5-7.
    CrossRef  |  Direct Link  |  

  12. Wong, G.L.H., 2013. Update of liver fibrosis and steatosis with transient elastography (Fibroscan). Gastroenterol. Rep., 1: 19-26.
    CrossRef  |  

  13. Wong, G.L., J. Vergniol, P. Lo, W.S. Wong and J. Foucher et al., 2013. Non-Invasive assessment of liver fibrosis with transient elastography (FibroScan®): Applying the cut-offs of M probe to XL probe. Ann. Hepatol., 12: 570-580.
    PubMed  |  

  14. Wong, G.L., H.L. Chan, Z. Yu, H.Y. Chan, C.H. Tse and V.W. Wong, 2013. Liver fibrosis progression is uncommon in patients with inactive chronic hepatitis B: A prospective cohort study with paired transient elastography examination. J. Gastroenterol. Hepatol., 28: 1842-1848.
    CrossRef  |  PubMed  |  Direct Link  |  

  15. Wong, G.L., H.L. Chan, Z. Yu, H.Y. Chan, C.H. Tse and V.W. Wong, 2013. Liver fibrosis progression in chronic hepatitis B patients positive for hepatitis B e antigen: A prospective cohort study with paired transient elastography examination. J. Gastroenterol. Hepatol., 28: 1762-1769.
    CrossRef  |  PubMed  |  Direct Link  |  

  16. Wong, G.L., H.L. Chan, Y.K. Tse, H.Y. Chan, C.H. Tse, A.O. Lo and V.W. Wong, 2013. On-treatment alpha-fetoprotein is a specific tumor marker for hepatocellular carcinoma in patients with chronic hepatitis B receiving entecavir. Hepatology. 10.1002/hep.26739.
    CrossRef  |  PubMed  |  

  17. Wong, G.L., H.L. Chan, P.C. Choi, A.W. Chan, A.O. Lo, A.M. Chim and V.W. Wong, 2013. Association between anthropometric parameters and measurements of liver stiffness by transient elastography. Clin. Gastroenterol. Hepatol., 11: 295-302.
    CrossRef  |  PubMed  |  Direct Link  |  

  18. Wong, G.L., H.L. Chan, H.Y. Chan, C.H. Tse and Y.K. Tse et al., 2013. Accuracy of risk scores for patients with chronic hepatitis B receiving entecavir treatment. Gastroenterology, 144: 933-944.
    CrossRef  |  PubMed  |  Direct Link  |  

  19. Wong, G.L., H.L. Chan, C.K. Wong, C. Leung and C.Y. Chan et al., 2013. Liver stiffness-based optimization of hepatocellular carcinoma risk score in patients with chronic hepatitis B. J. Hepatol. 10.1016/j.jhep.2013.09.029.
    CrossRef  |  PubMed  |  Direct Link  |  

  20. Wong, G.L., H.L. Chan, C.H. Mak, S.K. Lee and Z.M. Ip et al., 2013. Entecavir treatment reduces hepatic events and deaths in chronic hepatitis B patients with liver cirrhosis. Hepatology, 58: 1537-1547.
    CrossRef  |  Direct Link  |  

  21. Wong, G.L., H.L. Chan, A.O. Lo, H.Y. Chan, C.H. Tse, A.M. Chim and V.W. Wong, 2013. Serum hepatitis B surface antigen kinetics in severe reactivation of hepatitis e antigen negative chronic hepatitis B patients receiving nucleos(t)ide analogues. Antivir. Ther. 10.3851/IMP2615.
    CrossRef  |  PubMed  |  

  22. Wong, G.L., 2013. Transient elastography: Kill two birds with one stone? World J. Hepatol., 5: 264-274.
    CrossRef  |  PubMed  |  

  23. Wong, G.L. and V.W. Wong, 2013. Risk prediction of hepatitis B virus-related hepatocellular carcinoma in the era of antiviral therapy. World J. Gastroenterol., 19: 6515-6522.
    CrossRef  |  PubMed  |  

  24. Lo, A.O., V.W. Wong, G.L.H. Wong, H.Y. Chan, C.M. Cheung and H.L. Chan, 2013. Efficacy of entecavir switch therapy in chronic hepatitis B patients with incomplete virological response to telbivudine. Antivir. Ther., 8: 671-679.
    PubMed  |  

  25. Liu, G.J., Q. Ji, F. Moriyasu, X.Y. Xie, W. Wang, G.L.H. Wong, M.X. Lin and M.D. Lu, 2013. Value of contrast-enhanced ultrasound using perflubutane microbubbles for diagnosing liver fibrosis and cirrhosis in rats. Ultrasound Med. Biol., 39: 2158-2165.
    CrossRef  |  PubMed  |  

  26. Leung, V.Y., J. Shen, V.W. Wong, J. Abrigo and G.L.H. Wong et al., 2013. Quantitative elastography of liver fibrosis and spleen stiffness in chronic hepatitis B carriers: Comparison of shear-wave elastography and transient elastography with liver biopsy correlation. Radiology, 269: 910-918.
    CrossRef  |  PubMed  |  

  27. Kwok, R., Y.K. Tse, G.L.H. Wong, Y. Ha and A.U. Lee et al., 2013. Systematic review with meta-analysis: Non-Invasive assessment of non-alcoholic fatty liver disease-the role of transient elastography and plasma cytokeratin-18 fragments. Aliment. Pharmacol. Ther. 10.1111/apt.12569.
    CrossRef  |  PubMed  |  

  28. Dai, C.Y., T.C. Tseng, G.L.H. Wong, J.F. Huang and V.W. Wong et al., 2013. Consolidation therapy for HBeAg-positive Asian chronic hepatitis B patients receiving lamivudine treatment: A multicentre study. J. Antimicrob. Chemother., 68: 2332-2338.
    CrossRef  |  PubMed  |  

  29. Abrigo, J.M., J. Shen, V.W. Wong, D.K. Yeung and G.L.H. Wong et al., 2013. Non-Alcoholic fatty liver disease: Spectral patterns observed from an in vivo phosphorus magnetic resonance spectroscopy study. J. Hepatol. 10.1016/j.jhep.2013.11.018.
    CrossRef  |  PubMed  |  Direct Link  |  

  30. Yu, Z., V.W. Wong and G.L.H. Wong, 2012. Non-Invasive algorithms for liver fibrosis. Aliment. Pharmacol. Ther., 35: 310-311.
    CrossRef  |  Direct Link  |  

  31. Yu, Z., G.L.H. Wong and V.W. Wong, 2012. Commentary: Time to update the ALT cut-off? Aliment. Pharmacol. Ther., 36: 682-683.
    CrossRef  |  Direct Link  |  

  32. Wong, V.W., W.C. Chu, G.L.H. Wong, R.S. Chan and A.M. Chim et al., 2012. Prevalence of non-alcoholic fatty liver disease and advanced fibrosis in Hong Kong Chinese: A population study using proton-magnetic resonance spectroscopy and transient elastography. Gut, 61: 409-415.
    CrossRef  |  PubMed  |  

  33. Wong, V.W., J. Vergniol, G.L.H. Wong, J. Foucher and A.W. Chan et al., 2012. Liver stiffness measurement using XL probe in patients with nonalcoholic fatty liver disease. Am. J. Gastroenterol., 107: 1862-1871.
    CrossRef  |  PubMed  |  

  34. Wong, V.W., G.L.H. Wong, W.C. Chu, A.M. Chim and A. Ong et al., 2012. Hepatitis B virus infection and fatty liver in the general population. J. Hepatol., 56: 533-540.
    CrossRef  |  PubMed  |  Direct Link  |  

  35. Wong, V.W., G.L.H. Wong, C.H. Tse, L.K. Yuen, H.Y. Chan, S.A. Locarnini and H.L. Chan, 2012. Antiviral drug resistance testing in patients with chronic hepatitis B. Dig. Dis. Sci., 57: 221-231.
    CrossRef  |  PubMed  |  Direct Link  |  

  36. Wong, G.L.H., V.W. Wong, H.Y. Chan, P.C. Tse and J. Wong et al., 2012. Undetectable HBV DNA at month 12 of entecavir treatment predicts maintained viral suppression and HBeAg-seroconversion in chronic hepatitis B patients at 3 years. Aliment. Pharmacol. Ther., 35: 1326-1335.
    CrossRef  |  PubMed  |  Direct Link  |  

  37. Wong, G.L.H., K.W. Au, A.O. Lo, Y.K. Tse, J.Y. Ching, K.F. To and F.K. Chan, 2012. Gastroprotective therapy does not improve outcomes of patients with Helicobacter pylori-negative idiopathic bleeding ulcers. Clin. Gastroenterol. Hepatol., 10: 1124-1129.
    CrossRef  |  Direct Link  |  

  38. Wong, G.L.H., 2012. How does hepatitis B virus infection react to hepatocellular carcinoma treatment? J. Gastroenterol. Hepatol., 27: 1-2.
    CrossRef  |  PubMed  |  Direct Link  |  

  39. Wong, G.L.H. and V.W. Wong, 2012. Commentary: Predicting survival in hepatocellular carcinoma patients. Aliment. Pharmacol. Ther., 36: 680-680.
    CrossRef  |  Direct Link  |  

  40. Sonneveld, M.J., V.W. Wong, A.M. Woltman, G.L.H. Wong and Y. Cakaloglu et al., 2012. Polymorphisms near IL28B and serologic response to peginterferon in HBeAg-positive patients with chronic hepatitis B. Gastroenterology, 142: 513-520.
    CrossRef  |  PubMed  |  

  41. Shen, J., H.L. Chan, G.L.H. Wong, P.C. Choi and A.W. Chan et al., 2012. Non-invasive diagnosis of non-alcoholic steatohepatitis by combined serum biomarkers. J. Hepatol., 56: 1363-1370.
    CrossRef  |  PubMed  |  

  42. Shen, J., H.L. Chan, G.L.H. Wong, A.W. Chan and P.C. Choi et a., 2012. Assessment of non-alcoholic fatty liver disease using serum total cell death and apoptosis markers. Aliment. Pharmacol. Ther., 36: 1057-1066.
    CrossRef  |  PubMed  |  

  43. De Ledinghen, V., V.W. Wong, J. Vergniol, G.L.H. Wong and J. Foucher et al., 2012. Diagnosis of liver fibrosis and cirrhosis using liver stiffness measurement: Comparison between M and XL probe of FibroScan®. J. Hepatol., 56: 833-839.
    CrossRef  |  PubMed  |  

  44. Chan, S.L., F.K. Mo, V.W. Wong, G.S. Liem and G.L.H. Wong et al., 2012. Use of antiviral therapy in surveillance: Impact on outcome of hepatitis B-related hepatocellular carcinoma. Liver Int., 32: 271-278.
    CrossRef  |  PubMed  |  

  45. Wu, J.C., L.H. Lai, D.K. Chow, G.L.H. Wong, J.J. Sung and F.K. Chan, 2011. Concomitant irritable bowel syndrome is associated with failure of step-down on-demand proton pump inhibitor treatment in patients with gastro-esophageal reflux disease. Neurogastroenterol. Motil., 23: 155-160.
    CrossRef  |  PubMed  |  

  46. Wong, V.W., G.L.H. Wong, S.W. Tsang, T. Fan and W.C. Chu et al., 2011. High prevalence of colorectal neoplasm in patients with non-alcoholic steatohepatitis. Gut, 60: 829-836.
    CrossRef  |  PubMed  |  

  47. Wong, V.W., G.L.H. Wong, K.K. Yiu, A.M. Chim and S.H. Chu et al., 2011. Entecavir treatment in patients with severe acute exacerbation of chronic hepatitis B. J. Hepatol., 54: 236-242.
    CrossRef  |  PubMed  |  Direct Link  |  

  48. Wong, V.W., G.L.H. Wong, G.W. Yip, A.O. Lo and J. Limquiaco et al., 2011. Coronary artery disease and cardiovascular outcomes in patients with non-alcoholic fatty liver disease. Gut, 60: 1721-1727.
    CrossRef  |  PubMed  |  

  49. Wong, J.S., G.L.H. Wong, K.K. Tsoi, V.W. Wong and S.Y. Cheung et al., 2011. Meta-analysis: The efficacy of anti-viral therapy in prevention of recurrence after curative treatment of chronic hepatitis B-related hepatocellular carcinoma. Aliment. Pharmacol. Ther., 33: 1104-1112.
    CrossRef  |  PubMed  |  Direct Link  |  

  50. Wong, G.L.H., V.W. Wong, P.C. Choi, A.W. Chan and A.M. Chim et al., 2011. On-Treatment monitoring of liver fibrosis with transient elastography in chronic hepatitis B patients. Antivir. Ther., 16: 165-172.
    CrossRef  |  PubMed  |  

  51. Wong, G.L.H., V.W. Wong, A.M. Chim, K.K. Yiu, S.H. Chu, M.K. Li and H.L. Chan, 2011. Factors associated with unreliable liver stiffness measurement and its failure with transient elastography in the Chinese population. J. Gastroenterol. Hepatol., 26: 300-305.
    CrossRef  |  PubMed  |  Direct Link  |  

  52. Wong, G.L.H., V.W. Wong and H.L. Chan, 2011. Is transient elastography inaccurate in chronic hepatitis B and non-alcoholic fatty liver disease? J. Hepatol., 55: 497-497.
    CrossRef  |  PubMed  |  Direct Link  |  

  53. Wong, G.L.H. and V.W. Wong, 2011. Medical therapy for primary sclerosing cholangitis. Aliment. Pharmacol. Ther., 34: 1135-1136.
    CrossRef  |  Direct Link  |  

  54. Ong, A., V.W. Wong, G.L.H. Wong, H.Y. Chan, C.H. Tse and H.L. Chan et al., 2011. Management options for lamivudine-resistant chronic hepatitis B patients with suboptimal virological suppression by adefovir. Aliment. Pharmacol. Ther., 34: 972-981.
    CrossRef  |  PubMed  |  

  55. Ong, A., V.W. Wong, G.L.H. Wong and H.L. Chan, 2011. The effect of caffeine and alcohol consumption on liver fibrosis-a study of 1045 Asian hepatitis B patients using transient elastography. Liver Int., 31: 1047-1053.
    CrossRef  |  Direct Link  |  

  56. Chan, H.L., G.L.H. Wong, C.H. Tse, H.Y. Chan and V.W. Wong, 2011. Viral determinants of hepatitis B surface antigen seroclearance in hepatitis B e antigen-negative chronic hepatitis B patients. J. Infect. Dis., 204: 408-414.
    CrossRef  |  PubMed  |  

  57. Chan, H.L., G.L.H. Wong, A.M. Chim, H.Y. Chan, S.H. Chu and V.W. Wong, 2011. Prediction of off-treatment response to lamivudine by serum hepatitis B surface antigen quantification in hepatitis B e antigen-negative patients. Antivir. Ther., 16: 1249-1257.
    CrossRef  |  PubMed  |  

  58. Yan, K.K., G.L.H. Wong, V.W. Wong and H.L. Chan, 2010. Rate and factors affecting treatment uptake of patients with chronic hepatitis C in a tertiary referral hospital. Dig. Dis. Sci., 55: 3541-3547.
    CrossRef  |  PubMed  |  Direct Link  |  

  59. Wong, V.W., S.L. Chan, F. Mo, T.C. Chan and H.H. Loong et al., 2010. Clinical scoring system to predict hepatocellular carcinoma in chronic hepatitis B carriers. J. Clin. Oncol., 28: 1660-1665.
    CrossRef  |  PubMed  |  

  60. Wong, V.W., J. Vergniol, G.L. Wong, J. Foucher and H.L. Chan et al., 2010. Diagnosis of fibrosis and cirrhosis using liver stiffness measurement in nonalcoholic fatty liver disease. Hepatology, 51: 454-462.
    PubMed  |  

  61. Wong, V.W., G.L.H. Wong, K.K. Yan, A.M. Chim and H.Y. Chan et al., 2010. Durability of peginterferon alfa-2b treatment at 5 years in patients with hepatitis B e antigen-positive chronic hepatitis B. Hepatology, 51: 1945-1953.
    CrossRef  |  PubMed  |  Direct Link  |  

  62. Wong, V.W., G.L. Wong, P.C. Choi, A.W. Chan and M.K. Li et al., 2010. Disease progression of non-alcoholic fatty liver disease: A prospective study with paired liver biopsies at 3 years. Gut, 59: 969-974.
    CrossRef  |  

  63. Wong, V.W., G.L. Wong, J. Yu, P.C. Choi and A.W. Chan et al., 2010. Interaction of adipokines and hepatitis B virus on histological liver injury in the chinese. Am. J. Gastroenterol., 105: 132-138.
    PubMed  |  

  64. Wong, G.L.H., V.W. Wong, P.C. Choi, A.W. Chan and H.L. Chan, 2010. Development of a non-invasive algorithm with transient elastography (Fibroscan) and serum test formula for advanced liver fibrosis in chronic hepatitis B. Aliment. Pharmacol. Ther., 31: 1095-1103.
    CrossRef  |  PubMed  |  Direct Link  |  

  65. Wong, G.L.H., K.K. Yiu, V.W. Wong, K.K. Tsoi and H.L. Chan, 2010. Meta-analysis: Reduction in hepatic events following interferon-alfa therapy of chronic hepatitis B. Aliment. Pharmacol. Ther., 32: 1059-1068.
    CrossRef  |  PubMed  |  Direct Link  |  

  66. Lui, Y.Y., K.K. Tsoi, V.W. Wong, J.H. Kao and J.L. Hou et al., 2010. Cost-Effectiveness analysis of roadmap models in chronic hepatitis B using tenofovir as the rescue therapy. Antivir. Ther., 15: 145-155.
    PubMed  |  

  67. Chan, H.L., V.W. Wong, G.L.H. Wong, C.H. Tse, H.Y. Chan and J.J. Sung, 2010. A longitudinal study on the natural history of serum hepatitis B surface antigen changes in chronic hepatitis B. Hepatology, 52: 1232-1241.
    CrossRef  |  PubMed  |  

  68. Chan, H.L., V.W. Wong, A.M. Chim, H.Y. Chan, G.L.H. Wong and J.J. Sung, 2010. Serum HBsAg quantification to predict response to peginterferon therapy of e antigen positive chronic hepatitis B. Aliment. Pharmacol. Ther., 32: 1323-1331.
    CrossRef  |  PubMed  |  

  69. Wong, V.W., J. Yu, A.S. Cheng, G.L. Wong and H.Y. Chan et al., 2009. High serum interleukin-6 level predicts future hepatocellular carcinoma development in patients with chronic hepatitis B. Int. J. Cancer, 124: 2766-2770.
    CrossRef  |  PubMed  |  Direct Link  |  

  70. Wong, V.W., G.L.H. Wong, S.W. Tsang, A.Y. Hui and A.W. Chan et al., 2009. Metabolic and histological features of non-alcoholic fatty liver disease patients with different serum alanine aminotransferase levels. Aliment. Pharmacol. Ther., 29: 387-396.
    CrossRef  |  PubMed  |  Direct Link  |  

  71. Wong, V.W., G.L.H. Wong, A.M. Chim, P.C. Choi and A.W. Chan et al., 2009. Surrogate end points and long-term outcome in patients with chronic hepatitis B. Clin. Gastroenterol. Hepatol., 7: 1113-1120.
    CrossRef  |  PubMed  |  Direct Link  |  

  72. Wong, G.L.H., V.W. Wong, Y. Chan, J.Y. Ching and K. Au et al., 2009. High incidence of mortality and recurrent bleeding in patients with Helicobacter pylori-negative idiopathic bleeding ulcers. Gastroenterology, 137: 525-531.
    CrossRef  |  PubMed  |  Direct Link  |  

  73. Wong, G.L.H., V.W. Wong, P.C. Choi, A.W. Chan and A.M. Chim et al., 2009. Metabolic syndrome increases the risk of liver cirrhosis in chronic hepatitis B. Gut, 58: 111-117.
    CrossRef  |  PubMed  |  

  74. Wong, G.L.H., V.W. Wong, P.C. Choi, A.W. Chan and A.M. Chim et al., 2009. Increased liver stiffness measurement by transient elastography in severe acute exacerbation of chronic hepatitis B. J. Gastroenterol. Hepatol., 24 : 1002-1007.
    CrossRef  |  PubMed  |  Direct Link  |  

  75. Wong, G.L.H., V.W. Wong, P.C. Choi, A.W. Chan and A.M. Chim et al., 2009. Clinical factors associated with liver stiffness in hepatitis B e antigen-positive chronic hepatitis B patients. Clin. Gastroenterol. Hepatol., 7: 227-233.
    CrossRef  |  PubMed  |  Direct Link  |  

  76. Wong, G.L.H., H.X. Xu and X.Y. Xie, 2009. Detection of focal liver lesions in cirrhotic liver using contrast-enhanced ultrasound. World J. Radiol., 1: 25-36.

  77. Wong, G.L.H. and H.L. Chan, 2009. Predictors of treatment response in chronic hepatitis B. Drugs, 69: 2167-2177.
    CrossRef  |  PubMed  |  Direct Link  |  

  78. Limquiaco, J.L., J. Wong, V.W. Wong, G.L.H. Wong and C.H. Tse et al., 2009. Lamivudine monoprophylaxis and adefovir salvage for liver transplantation in chronic hepatitis B: A seven-year follow-up study. J. Med. Virol., 81: 224-229.
    CrossRef  |  PubMed  |  Direct Link  |  

  79. Limquiaco, J.L., G.L.H. Wong, V.W. Wong, P.B. Lai and H.L. Chan, 2009. Evaluation of model for end stage liver disease (MELD)-based systems as prognostic index for hepatocellular carcinoma. J. Gastroenterol. Hepatol., 24: 63-69.
    CrossRef  |  PubMed  |  

  80. Li, X.X., G.L.H. Wong, K.F. To, V.W.S. Wong and L.H. Lai et al., 2009. Bacterial microbiota profiling in gastritis without Helicobacter pylori infection or non-steroidal anti-inflammatory drug use. PLoS One, Vol. 4. 10.1371/journal.pone.0007985.
    CrossRef  |  Direct Link  |  

  81. Leung, W.K., J.Y. Lau, B.Y. Suen, G.L.H. Wong and D.K. Chow et al., 2009. Repeat-Screening colonoscopy 5 years after normal baseline-screening colonoscopy in average-risk Chinese: A prospective study. Am. J. Gastroenterol., 104: 2028-2034.
    CrossRef  |  PubMed  |  

  82. Lee, Y.T., L.Y. Lai, A.J. Hui, V.W. Wong and J.Y. Ching et al., 2009. Efficacy of cap-assisted colonoscopy in comparison with regular colonoscopy: A randomized controlled trial. Am. J. Gastroenterol., 104: 41-46.
    CrossRef  |  PubMed  |  

  83. Chan, H.L., V.W. Wong, G.L.H. Wong, A.M. Chim, L.H. Lai and J.J. Sung, 2009. Evaluation of impact of serial hepatitis B virus DNA levels on development of hepatocellular carcinoma. J. Clin. Microbiol., 47: 1830-1836.
    CrossRef  |  PubMed  |  

  84. Chan, H.L., G.L.H. Wong, P.C. Choi, A.W. Chan and A.M. Chim et al., 2009. Alanine aminotransferase-based algorithms of liver stiffness measurement by transient elastography (Fibroscan) for liver fibrosis in chronic hepatitis B. J. Viral. Hepat., 16: 36-44.
    CrossRef  |  PubMed  |  

  85. Chan, H.L., G.L.H. Wong, C.H. Tse, A.M. Chim and K.K. Yiu et al., 2009. Hepatitis B virus genotype C is associated with more severe liver fibrosis than genotype B. Clin. Gastroenterol. Hepatol., 7: 1361-1366.
    CrossRef  |  PubMed  |  Direct Link  |  

  86. Chan, H.L., G.L.H. Wong and V.W. Wong, 2009. A review of the natural history of chronic hepatitis B in the era of transient elastography. Antivir. Ther., 14: 489-499.
    PubMed  |  

  87. Wong, V.W., G.L.H. Wong, S.W. Tsang, A.Y. Hui and A.W. Chan et al., 2008. Genetic polymorphisms of adiponectin and tumor necrosis factor-alpha and nonalcoholic fatty liver disease in Chinese people. J. Gastroenterol. Hepatol., 23: 914-921.
    CrossRef  |  PubMed  |  

  88. Wong, V.W., G.L.H. Wong, S.W. Tsang, A.Y. Hui and A.M. Chim et al., 2008. Long-term follow-up of lamivudine treatment in patients with severe acute exacerbation of hepatitis B e antigen (HBeAg)-positive chronic hepatitis B. Antivir. Ther., 13: 571-579.
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  89. Wong, V.W., G.L.H. Wong, A.M. Chim, A.M. Tse and S.W. Tsang et al., 2008. Validation of the NAFLD fibrosis score in a Chinese population with low prevalence of advanced fibrosis. Am. J. Gastroenterol., 103: 1682-1688.
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  90. Wong, G.L.H., V.W.S. Wong, P.C.L. Choi, A.W.H. Chan and A.M.L. Chim et al., 2008. Evaluation of alanine transaminase and hepatitis B virus DNA to predict liver cirrhosis in hepatitis B e antigen-negative chronic hepatitis B using transient elastography. Am. J. Gastroenterol., 103: 3071-3081.
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  91. Wong, G.L.H., V.W. Wong, P.C. Choi, A.W. Chan and R.H. Chum et al., 2008. Assessment of fibrosis by transient elastography compared with liver biopsy and morphometry in chronic liver diseases. Clin. Gastroenterol. Hepatol., 6: 1027-1035.
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  92. Wong, G.L.H., V.W. Wong, G.M. Tan, K.I. Ip and W.K. Lai et al., 2008. Surveillance programme for hepatocellular carcinoma improves the survival of patients with chronic viral hepatitis. Liver Int., 28: 79-87.
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  93. Wong, G.L.H., F.M. Law, V.W. Wong, A.Y. Hui, F.K. Chan, J.J. Sung and H.L. Chan, 2008. Health-related quality of life in Chinese patients with primary biliary cirrhosis. J. Gastroenterol. Hepatol., 23: 592-598.
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  94. Chow, D.K., R.W. Leong, L.H. Lai, G.L.H. Wong, W.K. Leung, F.K. Chan and J.J. Sung, 2008. Changes in Crohn's disease phenotype over time in the Chinese population: Validation of the Montreal classification system. Inflamm. Bowel. Dis., 14: 536-541.
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  95. Chan, H.L., V.W. Wong, G.L.H. Wong, A.M. Chim, H.Y. Chan and J.J. Sung, 2008. Early hepatitis B virus DNA suppression can predict virologic response to peginterferon and lamivudine treatment. Clin. Gastroenterol. Hepatol., 6: 1022-1026.
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  96. Chan, H.L., V.W. Wong, A.M. Chim, G.L.H. Wong, H.Y. Chan and J.J. Sung, 2008. Treatment of patients with chronic hepatitis B who have failed previous antiviral treatment with pegylated interferon alpha2a (40 kda: PEGASYS). Antivir. Ther., 13: 555-562.
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  97. Chan, H.L., C.H. Tse, F. Mo, J. Koh and V.W. Wong et al., 2008. High viral load and hepatitis B virus subgenotype Ce are associated with increased risk of hepatocellular carcinoma. J. Clin. Oncol., 26: 177-182.
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  98. Wong, V.W., A.M. Chim, G.L.H. Wong, J.J. Sung and H.L. Chan, 2007. Performance of the new MELD-Na score in predicting 3-month and 1-year mortality in Chinese patients with chronic hepatitis B. Liver Transpl., 13: 1228-1235.
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  99. Lai, L.H., G.L.H. Wong, J.Y. Lau, J.J. Sung and W.K. Leung, 2007. Initial experience of real-time capsule endoscopy in monitoring progress of the videocapsule through the upper GI tract. Gastrointest. Endosc., 66: 1211-1214.

  100. Chan, H.L., V.W. Wong, C.H. Tse, A.M. Chim, H.Y. Chan, G.L.H. Wong, and J.J. Sung, 2007. Early virological suppression is associated with good maintained response to adefovir dipivoxil in lamivudine resistant chronic hepatitis B. Aliment. Pharmacol. Ther., 25: 891-898.
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  101. Chan, H.L., V.W. Wong, A.M. Tse, C.H. Tse and A.M. Chim et al., 2007. Serum hepatitis B surface antigen quantitation can reflect hepatitis B virus in the liver and predict treatment response. Clin. Gastroenterol. Hepatol., 5: 1462-1468.
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  102. Chan, H.L., V.W. Wong, A.M. Chim, P.C. Choi and H.Y. Chan et al., 2007. Virological response to different combination regimes of peginterferon alpha-2b and lamivudine in hepatitis B e antigen positive chronic hepatitis B. Antivir. Ther., 12: 815-823.
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  103. Chan, F.K., V.W. Wong, B.Y. Suen, J.C. Wu and J.Y. Ching et al., 2007. Combination of a cyclo-oxygenase-2 inhibitor and a proton-pump inhibitor for prevention of recurrent ulcer bleeding in patients at very high risk: A double-blind, randomised trial. Lancet, 369: 1621-1626.
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  104. Wong, V.W., A.Y. Hui, S.W. Tsang, J.L. Chan and G.L.H. Wong et al., 2006. Prevalence of undiagnosed diabetes and postchallenge hyperglycaemia in Chinese patients with non-alcoholic fatty liver disease. Aliment. Phar. Ther., 24: 1215-1222.
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  105. Wong, V.W., A.Y. Hui, S.W. Tsang, J.L. Chan and A.M. Tse et al., 2006. Metabolic and adipokine profile of Chinese patients with nonalcoholic fatty liver disease. Clin. Gastroenterol. Hepatol., 4: 1154-1161.
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  106. Wong, G.L.H., L.H. Lai, J.Y. Lau, J.J. Sung and W.K. Leung, 2006. Prolonged esophageal transit during wireless capsule endoscopy: A series of five cases and analysis of risk factors. J. Clin. Gastroenterol., 40: 176-176.
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  107. Lai, LH., G.L.H. Wong, D.K. Chow, J.Y. Lau, J.J. Sung and W.K. Leung, 2006. Inter-Observer variations on interpretation of capsule endoscopies. Eur. J. Gastroenterol. Hepatol., 18: 283-286.
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  108. Lai, L.H., G.L.H. Wong, D.K. Chow, J.Y. Lau, J.J. Sung and W.K. Leung, 2006. Long-Term follow-up of patients with obscure gastrointestinal bleeding after negative capsule endoscopy. Am. J. Gastroenterol., 101: 1224-1228.
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  109. Ding, C., V.W. Wong, K.C. Chow, H.Y. Chan and A.Y. Hui et al., 2006. Quantitative subtyping of hepatitis B virus reveals complex dynamics of YMDD motif mutants development during long-term lamivudine therapy. Antivir. Ther., 11: 1041-1049.
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  110. Chan, H.L., V.W. Wong, A.Y. Hui, S.W. Tsang and J.L. Chan et al., 2006. Long-Term lamivudine treatment is associated with a good maintained response in severe acute exacerbation of chronic HBeAg-negative hepatitis B. Antivir. Ther., 11: 465-471.
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  111. Chan, A.Y., E.K. Li, G.L.H. Wong and D.T. Liu, 2006. Cerebellum vasculopathy and normal tension glaucoma in systemic lupus erythematosus: Report of a case and review of the literature. Rheumatol. Int., 27: 101-102.
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  112. Wong, G.L.H., A.Y. Hui, V.W. Wong, F.K. Chan, J.J. Sung and H.L. Chan, 2005. A retrospective study on clinical features and prognostic factors of biopsy-proven primary biliary cirrhosis in Chinese patients. Am. J. Gastroenterol., 100: 2205-2211.
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  113. Wong, G.L.H. and H.L. Chan, 2005. Molecular virology in chronic hepatitis B: Genotypes. Hosp. Med., 66: 13-16.
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  114. Wong, G.L.H., K.M. Chow, A.Y.M. Wang and P.K.T. Li, 2004. Anasarca secondary to problems in three organs: One man with three diseases? Nephrol. Dial. Transplant., 19: 1651-1653.
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