Mr. Zhe-Yi Hu
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Mr. Zhe-Yi Hu

Researcher
Hutchison Whampoa Limited, China


Highest Degree
Ph.D. Student in Drug Metabolism and Pharmacokinetics from Chinese Academy of Sciences, China

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Area of Interest:

Pharmacology and Toxicology
100%
Clinical Pharmacology
62%
Pharmacokinetics
90%
Pharmacogenetics
75%
Bioanalysis
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
5
Abstracts
0

Selected Publications

  1. Hu, Z.Y., Q. Yu, Q. Pei and C. Guo, 2010. Dose-dependent association between UGT1A1*28 genotype and irinotecan-induced neutropenia: Low doses also increase risk. Clin. Cancer Res., 16: 3832-3842.
    CrossRef  |  PubMed  |  Direct Link  |  
  2. Hu, Z.Y. and Y.S. Zhao, 2010. Sex-dependent differences in cytochrome P450 3A activity as assessed by midazolam disposition in humans: A meta-analysis. Drug Metab. Dispos., 38: 817-823.
    CrossRef  |  PubMed  |  Direct Link  |  
  3. Sun, Y., J. Dai, Z.Y. Hu, F. Du and W. Niu et al., 2009. Oral bioavailability and brain penetration of (-)-stepholidine, a tetrahydroprotoberberine agonist at dopamine D(1) and antagonist at D(2) receptors, in rats. Br. J. Pharmacol., 158: 1302-1312.
    CrossRef  |  PubMed  |  Direct Link  |  
  4. Hu, Z.Y., Y.S. Zhao, D. Wu and Z.N. Cheng, 2009. Endogenous cortisol 6 beta-hydroxylation clearance is not an accurate probe for overall cytochrome P450 3A phenotyping in humans. Clin. Chim. Acta, 408: 92-97.
    CrossRef  |  PubMed  |  Direct Link  |  
  5. Hu, Z.Y., Q. Gong, X. Hu, L. Wang and Y. Cao et al., 2005. Simultaneous determination of 6beta-hydroxycortisol and cortisol in human urine and plasma by liquid chromatography with ultraviolet absorbance detection for phenotyping the CYP3A activity. J. Chromatogr. B Anal. Technol. Biomed. Life Sci., 826: 238-243.
    PubMed  |  Direct Link  |