Area of Interest:

Molecular Sciences

100%

Mouse Tumor Model

62%

DNA Repair

90%

Genomic Instability

75%

Histone Deacetylase

55%

Research Publications in Numbers

Books
0

Chapters
0

Articles
16

Abstracts
0

Selected Publications

Zhang, Y., M. Gostissa, D.G. Hildebrand, M.S. Becker and C. Boboila et al., 2010. The role of mechanistic factors in promoting chromosomal translocations found in lymphoid and other cancers. Adv. Immunol., 106: 93-133.
CrossRef | PubMed | Direct Link |
Zha, S., C. Guo, C. Boboila, V. Oksenych and H.L. Cheng et al., 2010. ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks. Nature, 469: 250-254.
CrossRef | PubMed | Direct Link |
Yamaguchi, T., F. Cubizolles, Y. Zhang, N. Reichert, H. Kohler, C. Seiser and P. Matthias, 2010. Histone deacetylases 1 and 2 act in concert to promote the G1-to-S progression. Genes Dev., 24: 455-469.
CrossRef | PubMed | Direct Link |
Grausenburger, R., I. Bilic, N. Boucheron, G. Zupkovitz and L. El-Housseiny et al., 2010. Conditional deletion of histone deacetylase 1 in T cells leads to enhanced airway inflammation and increased th2 cytokine production. J. Immunol., 185: 3489-3497.
CrossRef | PubMed | Direct Link |
Brunmeir, R., S. Lagger, E. Simboeck, A. Sawicka and G. Egger et al., 2010. Epigenetic regulation of a murine retrotransposon by a dual histone modification mark. PLoS Genet., 6: e1000927-e1000927.
CrossRef | PubMed | Direct Link |
Chakraborty, T., T. Perlot, R. Subrahmanyam, A. Jani and P.H. Goff et al., 2009. A 220-nucleotide deletion of the intronic enhancer reveals an epigenetic hierarchy in immunoglobulin heavy chain locus activation. J. Exp. Med., 206: 1019-1027.
CrossRef | PubMed |
Zhang, Y., S. Kwon, T. Yamaguchi, F. Cubizolles and S. Rousseaux et al., 2008. Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally. Mol. Cell Biol., 28: 1688-1701.
CrossRef | PubMed | Direct Link |
Li, G., F.W. Alt, H.L. Cheng, J.W. Brush and P.H. Goff et al., 2008. Lymphocyte-specific compensation for XLF/cernunnos end-joining functions in V(D)J recombination. Mol. Cell, 31: 631-640.
CrossRef | PubMed | Direct Link |
Kwon, S.H., Y. Zhang and P. Matthias, 2007. The deacetylase HDAC6 is a novel critical component of stress granules involved in the stress response. Genes Dev., 21: 3381-3394.
CrossRef | PubMed | Direct Link |
Boyault, C., Y. Zhang, S. Fritah, C. Caron and B. Gilquin et al., 2007. HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates. Genes Dev., 21: 2172-2181.
CrossRef | PubMed | Direct Link |
Zhang, Y. B. Gilquin, S. Khochbin and P. Matthias, 2006. Two catalytic domains are required for protein deacetylation. J. Biol. Chem., 281: 2401-2404.
CrossRef | PubMed | Direct Link |
Yan, C.T., D. Kaushal, M. Murphy, Y. Zhang and A. Datta et al., 2006. XRCC4 suppresses medulloblastomas with recurrent translocations in p53-deficient mice. Proc. Natl. Acad. Sci. USA., 103: 7378-7383.
CrossRef | PubMed | Direct Link |
Boyault, C., B. Gilquin, Y. Zhang, V. Rybin and E. Garman et al., 2006. HDAC6-p97/VCP controlled polyubiquitin chain turnover. EMBO J., 25: 3357-3366.
CrossRef | PubMed | Direct Link |
Li, N., Y. Zhang, M.J. Naylor, F. Schatzmann and F. Maurer et al., 2005. Β1 integrins regulate mammary gland proliferation and maintain the integrity of mammary alveoli. EMBO J., 24: 1942-1953.
CrossRef | PubMed | Direct Link |
Zhang, Y., N. Li, C. Caron, G. Matthias, D. Hess, S. Khochbin and P. Matthias, 2003. HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo. EMBO J., 22: 1168-1179.
CrossRef | PubMed | Direct Link |
He, Z., J. Bai and Y. Zhang, 1999. Effect of DNA methylation on protein-DNA interaction of HL-60 cells. Sci. China Series C: Life Sci., 42: 55-62.
CrossRef | PubMed |