Hi, I am Qiang Liu, My LiveDNA is 86.2214
 
   
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Dr. Qiang Liu
 
 
Institute: University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
 
Area of Interest: Biomedical Sciences
  •   Alzheimera`s Disease
  •   Obesity
  •   Neurodegenerative Disorders
  •   Lipid Metabolism
 
URL: http://livedna.org/86.2214
 
My SELECTED Publications
1:   Fuentealba, R., Q. Liu, J. Zhang, T. Kanekiyo and G. Bu, 2010. Low-density lipoprotein receptor-related protein 1 (LRP1) mediates neuronal Aβ42 uptake and lysosomal accumulation. PLoS ONE., 5: e11884-e11884.
CrossRef  |  
2:   Fuentealba, R.A., Q. Liu, T. Kanekiyo, J. Zhang and G. Bu, 2009. Low density lipoprotein receptor-related protein 1 promotes anti-apoptotic signaling in neurons by activating Akt survival pathway. J. Biol Chem., 284: 34045-34053.
PubMed  |  
3:   Grear, K.E., I.F. Ling, J.F. Simpson, J.L. Furman and C.R. Simmons et al., 2009. Expression of SORL1 and a novel SORL1 splice variant in normal and Alzheimers disease brain. Mol. Neurodegener., 4: 46-46.
CrossRef  |  
4:   Jen, A., C.J. Parkyn, R.C. Mootoosamy, M.J. Ford and A. Warley et al., 2010. Neuronal low-density lipoprotein receptor-related protein 1 binds and endocytoses prion fibrils via receptor cluster 4. J. Cell Sci., 123: 246-255.
Direct Link  |  
5:   Kanekiyo, T., J. Zhang, Q. Liu, C.C. Liu, L. Zhang and G. Bu, 2011. Heparan sulphate proteoglycan and the low-density lipoprotein receptor-related protein 1 constitute major pathways for neuronal amyloid-β uptake. J. Neurosci., 31: 1644-1651.
6:   Liu, Q. and B. Zhao, 2004. Nicotine attenuates beta-amyloid peptide induced neurotoxicity. Free Radic. Biol. Med., 36: S106-S106.
7:   Liu, Q. and B. Zhao, 2004. Nicotine attenuates beta-amyloid peptide-induced neurotoxicity, free radical and calcium accumulation in hippocampal neuronal cultures. Br. J. Pharmacol., 141: 746-754.
PubMed  |  
8:   Liu, Q., C.V. Zerbinatti, J. Zhang, H.S. Hoe and B. Wang et al., 2007. Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1. Neuron, 56: 66-78.
PubMed  |  
9:   Liu, Q., J. Zhang, C. Zerbinatti, Y. Zhan and B.J. Kolber et al., 2011. Lipoprotein receptor LRP1 regulates leptin signaling and energy homeostasis in the adult central nervous system. PLoS Biol., 9: e1000575-e1000575.
PubMed  |  
10:   Liu, Q., J. Zhang, H. Tran, M.M. Verbeek, K. Reiss, S. Estus and G. Bu, 2009. LRP1 shedding in human brain: roles of ADAM10 and ADAM17. Mol. Neurodegener., 4: 17-17.
CrossRef  |  
11:   Liu, Q., J. Zhang, H. Zhu, C. Qin, Q. Chen and B. Zhao, 2007. Dissecting the signaling pathway of nicotine-mediated neuroprotection in a mouse Alzheimer disease model. FASEB J., 21: 61-73.
CrossRef  |  
12:   Liu, Q., J. Zhang, J. Trotter, C. Cheng and X. Han et al., 2010. Lipoprotein receptor LRP1 regulates age-dependent synaptic and neuronal degeneration by modulating brain lipid metabolism. J. Neurosci., 30: 17068-17078.
13:   Liu, Q., Y. Tao and B.L. Zhao, 2003. ESR study on scavenging effect of nicotine on free radicals. Applied Magn. Reson., 24: 105-112.
CrossRef  |  
14:   Parkyn, C.J., E.G. Vermeulen, R.C. Mootoosamy, C. Sunyach and C. Jacobsen et al., 2008. LRP1 controls biosynthetic and endocytic trafficking of neuronal prion protein. J. Cell. Sci., 121: 773-783.
CrossRef  |  Direct Link  |  
15:   Yamada, K., T. Hashimoto, C. Yabuki, Y. Nagae and M. Tachikawa et al., 2008. The low density lipoprotein receptor-related protein 1 mediates uptake of amyloid beta peptides in an in vitro model of the blood-brain barrier cells. J. Biol. Chem., 283: 34554-34562.
PubMed  |  
16:   Zhang, J., Q. Liu, Q. Chen, N.Q. Liu and F.L. Li et al., 2006. Nicotine attenuates beta-amyloid-induced neurotoxicity by regulating metal homeostasis. FASEB J., 20: 1212-1214.
CrossRef  |  
17:   Zhang, J., Y. Li, Q. Liu, W. Lu and G. Bu, 2010. Wnt signaling activation and mammary gland hyperplasia in MMTV-LRP6 transgenic mice: Implication for breast cancer tumorigenesis. Oncogene, 29: 539-549.
PubMed  |  
18:   Zhang, Y.W., R. Wang, Q. Liu, H. Zhang, F.F. Liao and H. Xu, 2007. Presenilin/gamma-secretase-dependent processing of beta-amyloid precursor protein regulates EGF receptor expression. Proc. Natl. Acad. Sci. USA., 104: 10613-10618.
CrossRef  |