Dr. Guang-xiong Zhou
My Social Links

Dr. Guang-xiong Zhou

Professor
Jinan University, China

Highest Degree
Ph.D. in Medicinal Chemistry from Chinese Academy of Medical Sciences, China

Share this Profile

Area of Interest:

Medicine
100%
Natural Products Chemistry
62%
Traditional Chinese Drugs
90%
Biological Activity
75%
Medicinal Plants
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Zhang, Y.M., B.L. Liu, X.H. Zheng, X.J. Huang and H.Y. Li et al., 2017. Anandins A and B, two rare steroidal alkaloids from a marine Streptomyces anandii H41-59. Mar. Drugs, Vol. 15, No. 11. 10.3390/md15110355.
    CrossRef  |  Direct Link  |  
  2. Wang, F., S.N. Fu, Y.X. Bao, Y. Yang, H.F. Shen, B.R. Lin and G.X. Zhou, 2017. Kitamycin C, a new antimycin-type antibiotic from Streptomyces antibioticus strain 200-09. Nat. Prod. Res., 31: 1819-1824.
    CrossRef  |  Direct Link  |  
  3. Li, X.S., X.H. Zheng, F. Chen, B.R. Lin and G.X. Zhou, 2017. A new secondary metabolite from the fermented mycelia of Streptomyces antibiotic H41-55. J. Asian Nat. Prod. Res., (In Press). 10.1080/10286020.2017.1349758.
    CrossRef  |  Direct Link  |  
  4. Hu, C., S.W. Zhou, F. Chen, X.H. Zheng, H.F. Shen, B.R. Lin and G.X. Zhou, 2017. Neoantimycins A and B, two unusual benzamido nine-membered dilactones from marine-derived Streptomyces antibioticus H12-15. Molecules, Vol. 22, No. 4. 10.3390/molecules22040557.
    CrossRef  |  Direct Link  |  
  5. Zhang, Y.M., H.Y. Li, C. Hu, H.F. Sheng, Y. Zhang, B.R. Lin and G.X. Zhou, 2016. Ergosterols from the culture broth of marine Streptomyces anandii H41-59. Mar. Drugs, Vol. 14, No. 5. 10.3390/md14050084.
    CrossRef  |  Direct Link  |  
  6. Shao, F.Y., S. Wang, H.Y. Li, W.B. Chen and G.C. Wang et al., 2016. EM23, a natural sesquiterpene lactone, targets thioredoxin reductase to activate JNK and cell death pathways in human cervical cancer cells. Oncotarget, 7: 6790-6808.
    CrossRef  |  Direct Link  |  
  7. Li, H., M. Li, G. Wang, F. Shao and W. Chen et al., 2016. EM23, a natural sesquiterpene lactone from Elephantopus mollis, induces apoptosis in human myeloid leukemia cells through thioredoxin- and reactive oxygen species-mediated signaling pathways. Front. Pharmacol., Vol. 7. 10.3389/fphar.2016.00077.
    CrossRef  |  Direct Link  |  
  8. Fu, S., F. Wang, H. Li, Y. Bao and Y. Yang et al., 2016. Secondary metabolites from marine-derived Streptomyces antibioticus strain H74-21. Nat. Prod. Res., 30: 2460-2467.
    CrossRef  |  Direct Link  |  
  9. Zou, H.L., H.Y. Li, B.L. Liu and G.X. Zhou, 2015. A new cytotoxic benzophenanthridine isoquinoline alkaloid from the fruits of Macleaya cordata. J. Asian Nat. Prod. Res., 17: 856-860.
    CrossRef  |  Direct Link  |  
  10. Yu, S.F., X.J. Huang, S.N. Fu, C. Wu, W.C. Ye and G.X. Zhou, 2015. New monoterpenoids from fruits of Gardenia jasminoides var. radicans. Helv. Chim. Acta, 98: 1267-1272.
    CrossRef  |  Direct Link  |  
  11. Yu, S., S. Fu, B. Liu, Y. Zhang and G. Zhou, 2015. Two new quercetin glycoside derivatives from the fruits of Gardenia jasminoides var. radicans. Nat. Prod. Res., 29: 1336-1341.
    CrossRef  |  Direct Link  |  
  12. Wu, C., R.L. Zhang, H.Y. Li, C. Hu, B.L. Liu, Y.L. Li and G.X. Zhou, 2015. Triterpenoid saponins from the root bark of Schima superba and their cytotoxic activity on B16 melanoma cell line. Carbohydr. Res., 413: 107-114.
    CrossRef  |  Direct Link  |  
  13. Wu, B.L., H.L. Zou, F.M. Qin, H.Y. Li and G.X. Zhou, 2015. New Ent-Kaurane-type diterpene glycosides and benzophenone from Ranunculus muricatus Linn. Molecules, 20: 22445-22453.
    CrossRef  |  Direct Link  |  
  14. Wang, Q.Q., C. Wu, Y. Zhang, B.L. Liu and G.X. Zhou, 2015. A new flavonoid glucoside from Rhododendron seniavinii. J. Asian Nat. Prod. Res., 17: 778-782.
    CrossRef  |  Direct Link  |  
  15. Qin, F.M., B.L. Liu, Y. Zhang and G.X. Zhou, 2015. A new triterpenoid from the fruits of Gardenia jasminoides var. radicans Makino. Nat. Prod. Res., 29: 633-637.
    CrossRef  |  Direct Link  |  
  16. Xue, J.Y., G.X. Zhou, T. Chen, S. Gao, M.Y. Choi and Y.S. Wong, 2014. Desacetyluvaricin induces S phase arrest in SW480 colorectal cancer cells through superoxide overproduction. J. Cell. Biochem., 115: 464-475.
    CrossRef  |  Direct Link  |  
  17. Wu, C., Y.H. Duan, W. Tang, M.M. Li and X. Wu et al., 2014. New ursane-type triterpenoid saponins from the stem bark of Schefflera heptaphylla. Fitoterapia, 92: 127-132.
    CrossRef  |  Direct Link  |  
  18. Wu, C., Y.H. Duan, M.M. Li, W. Tang and X. Wu et al., 2013. Triterpenoid saponins from the stem barks of Schefflera heptaphylla. Planta Medica, 79: 1348-1355.
    CrossRef  |  Direct Link  |  
  19. Wu, C., C.S. Wei, S.F. Yu, B.L. Liu and Y.L. Li et al., 2013. Two new acetylated flavonoid glycosides from Phyllanthus urinaria. J. Asian Nat. Prod. Res., 15: 703-707.
    CrossRef  |  Direct Link  |  
  20. Wei, L.B., H.E. Yuan, J.M. Chen, Q.Q. Wang, H. Wang, W.C. Ye and G.X. Zhou, 2013. Five new cycloartane-type triterpenoid saponins from Nervilia fordii. Helv. Chim. Acta, 96: 150-157.
    CrossRef  |  Direct Link  |  
  21. Shu, W., C. Wu, Y. Zhang, W.C. Ye and G. Zhou, 2013. Two new steroidal glycosides isolated from the aerial part of Solanum torvum Swartz. Nat. Prod. Res., 27: 1982-1986.
    CrossRef  |  Direct Link  |  
  22. Qin, F.M., L.J. Meng, H.L. Zou and G.X. Zhou, 2013. Three new iridoid glycosides from the fruit of Gardenia jasminoides var. radicans. Chem. Pharmaceut. Bull., 61: 1071-1074.
    CrossRef  |  Direct Link  |  
  23. Chen, J.M., L.B. Wei, C.L. Lu and G.X. Zhou, 2013. A flavonoid 8-C-glycoside and a triterpenoid cinnamate from Nervilia fordii. J. Asian Nat. Prod. Res., 15: 1088-1093.
    CrossRef  |  Direct Link  |  
  24. Zhu, L.H., C. Chen, H. Wang, W.C. Ye and G.X. Zhou, 2012. Indole alkaloids from Alocasia macrorrhiza. Chem. Pharmaceut. Bull., 60: 670-673.
    CrossRef  |  Direct Link  |  
  25. Yu, J.Z., X.L. Wu, B. Yu, C.Q. Dai and K.L. Liu et al., 2012. The suppression effects of desacetyluvaricin on hepatocellular carcinoma and its possible mechanism. Pharmacogn. Mag., 8: 225-230.
    CrossRef  |  Direct Link  |  
  26. Wu, P., X.G. Li, N. Liang, G.C. Wang, W.C. Ye, G.X. Zhou and Y.L. Li, 2012. Two new sesquiterpene lactones from the supercritical fluid extract of Centipeda minima. J. Asian Nat. Prod. Res., 14: 515-520.
    CrossRef  |  Direct Link  |  
  27. Wei, L.B., J.M. Chen, W.C. Ye, X.S. Yao and G.X. Zhou, 2012. Three new cycloartane glycosides from Nervilia fordii. J. Asian Nat. Prod. Res., 14: 521-527.
    CrossRef  |  Direct Link  |  
  28. Huang, W.H., G.X. Zhou, G.C. Wang, H.Y. Chung, W.C. Ye and Y.L. Li, 2012. A new biflavonoid with antiviral activity from the roots of Wikstroemia indica. J. Asian Nat. Prod. Res., 14: 401-406.
    CrossRef  |  Direct Link  |  
  29. Zhou, G.X., R.Y. Chen and D.Q. Yu, 2011. Uvacalols I, J and K: New polyoxygenated cyclohexenes with all trans relative configurations from the roots of Uvaria calamistrata Hance. Nat. Prod. Res., 25: 161-168.
    CrossRef  |  Direct Link  |  
  30. Xu, L.Y., X.S. Quan, C. Wang, H.F. Sheng and G.X. Zhou et al., 2011. Antimycins A19 and A20, two new antimycins produced by marine actinomycete Streptomyces antibioticus H74-18. J. Antibiot., 64: 661-665.
    CrossRef  |  Direct Link  |  
  31. Jiao, W.H., H. Gao, F. Zhao, H.W. Lin, Y.M. Pan, G.X. Zhou and X.S. Yao, 2011. Anti-inflammatory alkaloids from the stems of Picrasma quassioides BENNET. Chem. Pharmaceut. Bull., 59: 359-364.
    CrossRef  |  Direct Link  |  
  32. Jiao, W.H., H. Gao, F. Zhao, F. He, G.X. Zhou and X.S. Yao, 2011. A new neolignan and a new sesterterpenoid from the stems of Picrasma quassioides Bennet. Chem. Biodivers., 8: 1163-1169.
    CrossRef  |  Direct Link  |  
  33. He, H.B., X.L. Wu, B. Yu, K.L. Liu and G.X. Zhou et al., 2011. The effect of desacetyluvaricin on the expression of TLR4 and P53 protein in Hepg 2.2.15. Hepatitis Monthly, 11: 364-367.
    Direct Link  |  
  34. Zhou, G.X., Y.J. Zhang, R.Y. Chen and D.Q. Yu, 2010. Three polyoxygenated cyclohexenes from Uvaria calamistrata. J. Asian Nat. Prod. Res., 12: 696-701.
    CrossRef  |  Direct Link  |  
  35. Zhou, G.X., S.Y. Mo, H.X. He, J.G. Shi, W.C. Ye, Z. Liu and R.W. Jiang, 2010. Molecular structure and tautomerization of the 1:1 complex of luteoskyrin and rugulosin. J. Mol. Struct., 979: 86-91.
    CrossRef  |  Direct Link  |  
  36. Xu, W., H. Wang, G.X. Zhou and X.S. Yao, 2010. Two new 8-O-4'-type lignans from the stem of Schima superba and their cell growth inhibitory activities against human cancer cell lines. J. Asian Nat. Prod. Res., 12: 874-878.
    CrossRef  |  Direct Link  |  
  37. Li, C.Y., H. Gao, W.H. Jiao, L. Zhang, G.X. Zhou and X.S. Yao, 2010. Three new diterpenoids from Rabdosia lophanthoides var. gerardiana. Helv. Chim. Acta, 93: 450-456.
    CrossRef  |  Direct Link  |  
  38. Jiao, W.H., H. Gao, C.Y. Li, G.X. Zhou, S. Kitanaka, A. Ohmura and X.S. Yao, 2010. β-Carboline alkaloids from the stems of Picrasma quassioides. Magn. Reson. Chem., 48: 490-495.
    CrossRef  |  Direct Link  |  
  39. Jiao, W.H., H. Gao, C.Y. Li, F. Zhao and R.W. Jiang et al., 2010. Quassidines A-D, bis-β-carboline alkaloids from the stems of Picrasma quassioides. J. Nat. Prod., 73: 167-171.
    CrossRef  |  Direct Link  |  
  40. Zhou, G.X., C.L. Lu, H.S. Wang and X.S. Yao, 2009. An acetyl flavonol from Nervilia fordii (Hance) Schltr. J. Asian Nat. Prod. Res., 11: 498-502.
    CrossRef  |  Direct Link  |  
  41. Dai, Y., G.X. Zhou, H. Kurihara, W.C. Ye and X.S. Yao, 2009. A biphenyl glycoside from Pyracantha fortuneana. Nat. Prod. Res., 23: 1163-1167.
    CrossRef  |  Direct Link  |  
  42. Zhou, G.X., Y. Zhang, R.Y. Chen and D.Q. Yu, 2008. Calamistrins H and I, two linear annonaceous acetogenins from the roots of Uvaria calamistrata Hance. Heterocycles, 75: 933-937.
    CrossRef  |  Direct Link  |  
  43. MacMillan, J.B., G. Xiong-Zhou, C.K. Skepper and T.F. Molinski, 2008. Phorbasides A-E, cytotoxic chlorocyclopropane macrolide glycosides from the marine sponge Phorbas sp. CD determination of C-methyl sugar configurations. J. Org. Chem., 73: 3699-3706.
    CrossRef  |  Direct Link  |  
  44. Hao, G., W. Zhao, Y. Lei, Y. Yang and Y. Zhi-Hong et al., 2008. Five new bidesmoside triterpenoid saponins from Stauntonia chinensis. Magn. Reson. Chem., 46: 630-637.
    CrossRef  |  Direct Link  |  
  45. Dai, Y., X.J. He, G.X. Zhou, H. Kurihara, W.C. Ye and X.S. Yao, 2008. Acylphloroglucinol glycosides from the fruits of Pyracantha fortuneana. J. Asian Nat. Prod. Res., 10: 111-117.
    CrossRef  |  Direct Link  |  
  46. Dai, Y., G.X. Zhou, H. Kurihara, W.C. Ye and X.S. Yao, 2008. Fortuneanosides G-L, dibenzofuran glycosides from the fruit of Pyracantha fortuneana. Chem. Pharmaceut. Bull., 56: 439-442.
    CrossRef  |  Direct Link  |  
  47. Zhou, X.L., X.J. He, G.X. Zhou, W.C. Ye and X.S. Yao, 2007. Pregnane glycosides from Solanum nigrum. J. Asian Nat. Prod. Res., 9: 517-523.
    CrossRef  |  Direct Link  |  
  48. Zhou, G.X., R.W. Jiang, Y. Cheng, W.C. Ye, J.G. Shi, N.B. Gong and Y. Lu, 2007. Daphnogirins A and B, two biflavones from Daphne giraldii. Chem. Pharmaceut. Bull., 55: 1287-1290.
    CrossRef  |  Direct Link  |  
  49. Yao, H., G.X. Zhou, Q. Wu, G.Q. Lei, D.F. Chen, J.K. Chen and T.S. Zhou, 2007. Mistletonone, a novel antioxidative diarylheptanoid from the branches and leaves of Viscum coloratum. Molecules, 12: 312-317.
    CrossRef  |  Direct Link  |  
  50. Skepper, C.K., J.B. MacMillan, G.X. Zhou, M.N. Masuno and T.F. Molinski, 2007. Chlorocyclopropane macrolides from the marine sponge Phorbas sp. assignment of the configurations of phorbasides A and B by quantitative CD. J. Am. Chem. Soc., 129: 4150-4151.
    CrossRef  |  Direct Link  |  
  51. Zhou, X., X. He, G. Wang, H. Gao, G. Zhou, W. Ye and X. Yao, 2006. Steroidal saponins from Solanum nigrum. J. Nat. Prod., 69: 1158-1163.
    CrossRef  |  Direct Link  |  
  52. Zhou, G.X. and T.F. Molinski, 2006. Manoalide derivatives from a sponge, Luffariella sp. J. Asian Nat. Prod. Res., 8: 15-20.
    CrossRef  |  Direct Link  |  
  53. Zhang, X.Q., G.C. Wang, W.C. Ye, Q. Li, G.X. Zhou and X.S. Yao, 2006. New diterpenoids from Andrographis paniculata (Burm. f.) Nees. J. Integr. Plant Biol., 48: 1122-1125.
    CrossRef  |  Direct Link  |  
  54. Dai, Y., G.X. Zhou, H. Kurihara, W.C. Ye and X.S. Yao, 2006. Biphenyl glycosides from the fruit of Pyracantha fortuneana. J. Nat. Prod., 69: 1022-1024.
    CrossRef  |  Direct Link  |  
  55. Zhou, G.X., E.K. Wijeratne, D. Bigelow, L.S. Pierson, H.D. VanEtten and A.L. Gunatilaka, 2004. Aspochalasins I, J and K: Three new cytotoxic cytochalasans of Aspergillus flavipes from the rhizosphere of Ericameria laricifolia of the Sonoran Desert. J. Nat. Prod., 67: 328-332.
    CrossRef  |  Direct Link  |  
  56. Mo, S., S. Wang, G. Zhou, Y. Yang, Y. Li, X. Chen and J. Shi, 2004. Phelligridins C-F:  Cytotoxic pyrano[4,3-c][2]benzopyran-1,6-dione and Furo[3,2-c]pyran-4-one derivatives from the fungus Phellinus igniarius. J. Nat. Prod., 67: 823-828.
    CrossRef  |  Direct Link  |  
  57. Meade-Tollin, L.C., E.K. Wijeratne, D. Cooper, M. Guild and E. Jon et al., 2004. Ponicidin and oridonin are responsible for the antiangiogenic activity of Rabdosia rubescens, a constituent of the herbal supplement PC SPES. J. Nat. Prod., 67: 2-4.
    CrossRef  |  Direct Link  |  
  58. Zhou, G.X. and T.F. Molinski, 2003. Long-chain acetylenic ketones from the Micronesian sponge Haliclona sp. importance of the 1-yn-3-ol group for antitumor activity. Mar. Drugs, 1: 46-53.
    CrossRef  |  Direct Link  |  
  59. Shi, J.G., W.Y. Hu, Y.C. Yang and G.X. Zhou, 2002. Phenolic glucosides from Alangium plantanifolium. J. Asian Nat. Prod. Res., 4: 47-51.
    CrossRef  |  Direct Link  |  
  60. Hu, W.Y., W.P. Xu, J.G. Shi, Y.C. Yang and G.X. Zhou, 2001. A phenolic glucoside from Alangium plantanifolium. Chin. Chem. Lett., 12: 793-796.
    Direct Link  |  
  61. Zhou, G.X., R.Y. Chen, Y.J. Zhang and D.Q. Yu, 2000. New annonaceous acetogenins from the roots of Uvaria calamistrata. J. Nat. Prod., 63: 1201-1204.
    CrossRef  |  Direct Link  |  
  62. Zhou, G.X., R.Y. Chen, Y.J. Zhang and D.Q. Yu, 2000. Calamistrin E, the first Annonaceous acetogenin with double bond in aliphatic chain from genus Uvaria. Chin. Chem. Lett., 11: 341-342.
    Direct Link  |  
  63. Zhou, G.X., R.Y. Chen, H. Chen and D.Q. Yu, 2000. Two new bis-tetrahydrofuran ring annonaceous acetogenins from the roots of Uvaria calamistrata. Chin. Chem. Lett., 11: 543-544.
    Direct Link  |  
  64. Shi, J.G., H.Q. Wang, M. Wang, Y.C. Yang, G.X. Zhou and W.Y. Hu, 2000. Two polyoxygenated pyrrolylpyridine and bipyrrole alkaloids from Speranskia tuberculata. Chin. Chem. Lett., 11: 785-788.
    Direct Link  |  
  65. Shi, J.G., H.Q. Wang, M. Wang, G.X. Zhou, Y.C. Yang and W.Y. Hu, 2000. Two novel poly-oxygen bipyridine alkaloids from Speranskia tuberculata. Chin. Chem. Lett., 11: 225-228.
    Direct Link  |  
  66. Zhou, G.X., R.Y. Chen and D.Q. Yu, 1999. New polyoxygenated cyclohexenes from Uvaria calamistrata. J. Asian Nat. Prod. Res., 1: 227-238.
    CrossRef  |  Direct Link  |  
  67. Zhou, G.X., L.E. Zhou, R.Y. Chen and D.Q. Yu, 1999. Calamistrins A and B, two new cytotoxic monotetrahydrofuran annonaceous acetogenins from Uvaria calamistrata. J. Nat. Prod., 62: 261-264.
    CrossRef  |  Direct Link  |  
  68. Zhang, Y.J., G.X. Zhou, R.Y. Chen and D.Q. Yu, 1999. Styryllactones from the rhizomes of Goniothalamus griffithii. J. Asian Nat. Prod. Res., 1: 189-197.
    CrossRef  |  Direct Link  |  
  69. Zhou, G.X., R.Y. Chen and D.Q. Yu, 1998. Two new polyoxygenated cyclohexenes from Uvaria calamistrata. Chin. Chem. Lett., 10: 935-938.
    Direct Link  |