Dr. Shiyou  Li

Dr. Shiyou Li

Research Director/VP of Research
Stephen F. Austin State University, USA


Highest Degree
Ph.D. in Forest Biology from Stephen F. Austin State University, USA

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Biography

Dr. Shiyou Li is currently working as Director at National Center for Pharmaceutical Crops, Arthur Temple College of Forestry and Agriculture, Stephen F. Austin State University, Nacogdoches, Texas, USA. He has completed his Ph.D. in Forest Biology from same University. His main area of interest focuses on Pharmacology and Toxicology. His area of expertise includes Endocides, Pharmaceutical Crops, Natural Products, Anticancer Compounds, Bioactive compounds, induced Autotoxicity, Species Pools, Saponins, Camptothecins, Curcumins, Diterpenoids, Triterpenoids, Secondary Metabolites, Trichome Chemistry, Invasive Species, Savinia, Camptotheca, Aesculus, Eryngium, Pterocarpus, and Curcuma. He has 50 publications in journals as author/co-author.

Area of Interest:

Plant and Soil Sciences
100%
Novel Natural Compounds
62%
Anti-Cancer Drugs
90%
Biosynthesis
75%
Metabolic Engineering
55%

Education

1993

Ph.D.

Stephen F. Austin State University, USA

Forest Biology

Selected Publications

  1. Wang, Y., B. Clack and S. Li, 2014. Genetic diversity in Camptotheca decaisne. Pharm. Crops, 5: 120-134.
    Direct Link  |  

  2. Wang, P. and S. Li, 2014. Phytochemistry of Camptotheca decasine. Pharm. Crops, 5: 163-172.

  3. Su, Z., P. Wang, W. Yuan and S. Li, 2014. Chemical constituents of Pterocarpus soyauxii. Nat. Prod. Commun., 9: 1483-1486.
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  4. Li, S., Z. Zhang, P.Wang and W. Yuan, 2014. Trichome management to enhance camptothecins in Camptotheca decaisne. Pharm. Crops, 5: 146-162.
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  5. Li, S., W. Zhang and D. Zhang, 2014. Distribution of Camptotheca decasine: Endangerous status. Pharm. Crops, 5: 135-139.

  6. Li, S., 2014. Taxonomy of Camptotheca decaisne. Pharm. Crops, 5: 89-99.

  7. Li, S., 2014. Phenolic variations in Camptotheca decaisne. Pharm. Crops, 5: 100-115.

  8. Li, S., 2014. Editorial: Development of Camptotheca decaisne as pharmaceutical crops. Pharm. Crops, 5: 85-88.

  9. Li, S. and W. Zhang, 2014. Ethnobotany of Camptotheca decasine: New discoveries of old medicinal uses. Pharm. Crops, 5: 140-145.
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  10. Li, S. and J. Taylor, 2014. Micromorphological variations of Camptotheca decasine. Pharm. Crops, 5: 116-119.
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  11. Yuan, W., P. Wang, Z. Zhang, Z. Su and S. Li, 2013. Triterpenoid saponins from Sesbania vesicaria. Phytochem. Lett., 6: 106-109.
    CrossRef  |  

  12. Yuan, W., P. Wang, Z. Su, V.S. Wang and S. Li, 2013. Cytotoxic triterpenoid saponins from husks of Aesculus californica(Spach) Nutt. Phytochemistry, 90: 95-105.
    CrossRef  |  

  13. Wang, P., W. Yuan, G. Deng, Z. Su and S.Y. Li, 2013. Triterpenoid saponins from Eryngium yuccifolium Kershaw Blue. Phytochem. Lett., 6: 306-309.
    CrossRef  |  

  14. Su, Z., W. Yuan, P. Wang and S. Li, 2013. Ethnobotany, phytochemistry and pharmacological activities of Taxodium rich. Pharm. Crops, 4: 1-14.
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  15. Su, Z., P. Wang, W. Yuan and S. Li, 2013. Flavonoids and 3-Arylcoumarin from Pterocarpus soyauxii. Planta Med., 79: 487-491.
    CrossRef  |  

  16. Su, Z., P. Wang, W. Yuan and S. Li, 2013. Chemical constituents from the fruit body of Chlorophyllum molybdites. Nat. Prod. Commun., 8: 1227-1228.
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  17. Li, S., P. Wang, G. Deng, W. Yuan and Z. Su, 2013. Cytotoxic compounds from invasive giant salvinia ( Salvinia molesta) against human tumor cells. Bioorg. Med. Chem. Lett., 23: 6682-6687.
    CrossRef  |  

  18. Gupta, S.C., B. Sung, J.H. Kim, S. Prasad, S.Y. Li and B.B. Aggarwal, 2013. Multitargeting by turmeric, the golden spice: From kitchen to clinic. Mol. Nutr. Food Res., 57: 1510-1528.
    CrossRef  |  Direct Link  |  

  19. Aggarwal, B.B., W. Yuan, S. Li and S.C. Gupta, 2013. Curcumin‐free turmeric exhibits anti‐inflammatory and anticancer activities: Identification of novel components of turmeric. Mol. Nutr. Food Res., 57: 1529-1542.
    CrossRef  |  

  20. Yuan, W., P. Wang, G. Deng and S. Li, 2012. Cytotoxic triterpenoid saponins from Aesculus glabra Willd. Phytochemistry, 75: 67-77.
    CrossRef  |  

  21. Wang, P., Z. Su, W. Yuan, G. Deng and S. Li, 2012. Phytochemical constituents and pharmacological activities of Eryngium L.(Apiaceae). Pharm. Crops, 3: 99-120.
    Direct Link  |  

  22. Peduto, A., R. Filosa, P. de Capparis, V. de Feo, S. Li, P. Wang and L. de Matino, 2012. 1-Methoxy-canthin-6-one and related β-carbolines: from natural compound to synthesis and biological activities. Stud. Nat. Prod. Chem., 38: 81-104.
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  23. Zhang, Z., W. Yuan, P. Wang, G. Grant and S. Li, 2011. Flavonoids from Lupinus texensis and their free radical scavenging activity. Nat. Prod. Res., 25: 1641-1649.
    CrossRef  |  

  24. Yuan, W., L. Zhou, G. Deng, P. Wang, D.L. Creech and S. Li, 2011. Anthocyanins, phenolics and antioxidant capacity of Vaccinium L. in Texas, USA. Pharm. Crops, 2: 8-20.
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  25. Yuan, W., L. Zhou, G. Deng, P. Wang, D. Creech and S. Li, 2011. Anthocyanins, phenolics and antioxidant capacity of Vaccinium L. in Texas, USA. Pharm. Crops, 2: 11-23.
    Direct Link  |  

  26. Li, S.Y., W. Yuan, G.R. Deng, P. Wang, P.Y. Yang and B.B. Aggarwal, 2011. Chemical composition and product quality control of turmeric (Curcuma longa L.). Pharm. Crops, 2: 28-54.
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  27. Zhang, Z., S. Ownby, P. Wang, W. Yuan, W. Zhang and S. Li, 2010. New phenolic compounds from Liatris elegans. Nat. Prod. Res., 24: 1079-1085.
    CrossRef  |  

  28. Zhang, Z., S. Li and X. Lian, 2010. An overview of the genus Aesculus L.: Ethnobotany, phytochemistry and pharmacological activities. Pharm. Crops, 1: 24-51.
    Direct Link  |  

  29. Yuan, W., P. Wang, Z. Zhang and S. Li, 2010. Glycosylation of (-)-maackiain by Beauveria bassiana and Cunninghamella echinulata var. elegans. Biocatalysis Biotransformation, 28: 117-121.
    CrossRef  |  Direct Link  |  

  30. Wang, P., S. Ownby, Z. Zhang, W. Yuan and S. Li, 2010. Cytotoxicity and inhibition of DNA topoisomerase I of polyhydroxylated triterpenoids and triterpenoid glycosides. Bioorg. Med. Chem. Lett., 20: 2790-2796.
    CrossRef  |  PubMed  |  

  31. Wang, P., G.R. Deng, W. Yuan and S.Y. Li, 2010. Cytotoxity of saponin-rich extracts from Phytolacca Americana L. (Phytolaccaceae). Planta Med., Vol. 76 10.1055/s-0030-1251849.
    CrossRef  |  

  32. Li, S.Y., W. Yuan, P.Y. Yang, M.D. Antoun, M.J. Balick and G.M. Cragg, 2010. Pharmaceutical crops: An overview. Pharm. Crops, 1: 1-17.
    Direct Link  |  

  33. Li, S.Y., P. Wang and W. Yuan, 2010. Induced endogenous autotoxicity in Camptotheca. Frontiers Biosci., E2: 1196-1210.

  34. Li, S., W. Yuan, P.Y. Yang, M.D. Antoun, M.J. Balick and G.M. Cragg, 2010. Pharmaceutical crops: An overview. Pharm. Crops, 1: 1-17.
    Direct Link  |  

  35. Li, S., P. Wang and W. Yuan, 2010. Induced endogenous autotoxicity in Camptotheca. Frontiers Biosci., E2: 1196-1210.
    CrossRef  |  Direct Link  |  

  36. Zhang, Z., X. Lian, S. Li and J.L. Stringer, 2009. Characterization of chemical ingredients and anticonvulsant activity of American skullcap (Scutellaria lateriflora). Phytomedicine, 16: 485-493.
    CrossRef  |  Direct Link  |  

  37. Wang, P., S. Li, S. Ownby, Z. Zhang, W. Yuan, W. Zhang and R.S. Beasley, 2009. Ecdysteroids and a sucrose phenylpropanoid ester from Froelichia floridana. Phytochemistry, 70: 430-436.
    CrossRef  |  

  38. Zhang, Z., S. Li, S. Ownby, P. Wang, W. Yuan, W. Zhang and R.S. Beasley, 2008. Phenolic compounds and rare polyhydroxylated triterpenoid saponins from Eryngium yuccifolium. Phytochemistry, 69: 2070-2080.
    CrossRef  |  Direct Link  |  

  39. Zhang, Z., P. Wang, W. Yuan and S. Li, 2008. Steroids, alkaloids and coumarins from Gelsemium sempervirens. Planta Med., 74: 1818-1822.
    CrossRef  |  

  40. Zhang, Z. and S. Li, 2007. Cytotoxic triterpenoid saponins from the fruits of Aesculus pavia L. Phytochemistry, 68: 2075-2086.
    CrossRef  |  Direct Link  |  

  41. Yuan, W., S. Li, S. Ownby, Z. Zhang, P. Wang, W. Zhang and R.S. Beasley, 2007. Flavonoids, coumarins and triterpenes from the aerial parts of Cnidoscolus texanus. Planta Med., 73: 1304-1308.
    CrossRef  |  

  42. Zhang, Z., S. Li, S.M. Zhang and D. Gorenstein, 2006. Triterpenoid saponins from the fruits of Aesculus pavia. Phytochemistry, 67: 784-794.
    CrossRef  |  Direct Link  |  

  43. Zhang, Z., S. Li, S. Zhang and D. Gorenstein, 2006. Triterpenoid saponins from the fruits of Aesculus pavia. Phytochemistry, 67: 784-794.
    CrossRef  |  

  44. Zhang, Z., S. Li and S. Zhang, 2005. Six new triterpenoid saponins from the root and stem bark of Cephalanthus occidentalis. Planta Med., 71: 355-361.
    CrossRef  |  

  45. Li, S.Y., Z.Z. Zhang, A. Cain, B. Wang, M. Long and J. Taylor, 2005. Anti-fungal activity of camptothecin, trifolin and hyperoside isolated from Camptotheca acuminate. J. Agric. Food Chem., 53: 32-37.

  46. Li, S., Z. Zhang, A. Cain, B. Wang, M. Long and J. Taylor, 2005. Anti-fungal activity of camptothecin, trifolin, and hyperoside isolated from Camptotheca acuminata. J. Agric. Food Chem., 53: 32-37.
    CrossRef  |  Direct Link  |  

  47. Zhang, Z., S. Li, S. Zhang, C. Liang, D. Gorenstein and R.S. Beasley, 2004. New camptothecin and ellagic acid analogues from the root bark of Camptotheca acuminate. Planta Medica, 70: 1216-1221.
    CrossRef  |  

  48. Zhang, Z., S. Li, S. Zhang, C. Liang, D. Gorenstein and R.S. Beasley, 2004. New Camptothecin and ellagic acid analogues from the root bark of Camptotheca acuminata. Planta Med., 70: 1216-1221.
    CrossRef  |  Direct Link  |  

  49. Li, S.Y., Y.J. Yi, Y.J. Wang, Z.Z. Zhang and R.S. Beasley, 2002. Camptothecin accumulation and variation in Camptotheca decaisne. Planta Medica, 68: 1010-1016.

  50. Li, S., Y. Yi, Y. Wang, Z. Zhang and R.S. Beasley, 2002. Camptothecin accumulation and variation in Camptotheca decaisne. Planta Med., 68: 1010-1016.
    CrossRef  |  Direct Link  |