Dr. Xuesong  Yang
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Dr. Xuesong Yang

Professor
Jinan University, China


Highest Degree
Ph.D. in Cell Membrane Physiology and Neurosciences from Tokyo Medical and Dental University, Japan

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Area of Interest:

Molecular Sciences
100%
Biochemistry
62%
Neuroscience
90%
Endocrinology
75%
Physiology
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Wang, G., Y. Li, X.Y. Wang, M. Chuai and J.Y.H. Chan et al., 2015. Mis-expression of BRE gene in the developing chick neural tube affects neurulation and somitogenesis. Mol. Biol. Cell, 26: 978-992.
    PubMed  |  
  2. Wang, G., W.Q. Huang, S.D. Cui, S. Li and X.Y. Wang et al., 2015. Autophagy is involved in high glucose-induced heart tube malformation. Cell Cycle, 14: 772-783.
    CrossRef  |  Direct Link  |  
  3. Wang, G., C.K. Yeung, J.L. Zhang, X.W. Hu and Y.X. Ye et al., 2015. High salt intake negatively impacts ovarian follicle development. Ann. Anatomy, 200: 79-87.
    CrossRef  |  Direct Link  |  
  4. Li, W., L. Huang, W. Lin, Q. Ke and R. Chen et al., 2015. Engraftable neural crest stem cells derived from cynomolgus monkey embryonic stem cells. Biomaterials, 39: 75-84.
    CrossRef  |  Direct Link  |  
  5. Gu, Q., C. Wang, G. Wang, Z. Han and Y. Li et al., 2015. Glipizide suppresses embryonic vasculogenesis and angiogenesis through targeting natriuretic peptide receptor A. Exp. Cell Res. 10.1016/j.yexcr.2015.03.012.
    CrossRef  |  Direct Link  |  
  6. Cheng, Y.S., X.Y. Wang, G. Wang, Y. Li and Y.L. Chen et al., 2015. Effects of anti-tumor drug sorafenib on chick embryo development. Anatomical Record. 10.1002/ar.23155.
    CrossRef  |  Direct Link  |  
  7. Cheng, X., R. Luo, G. Wang, C.J. Xu and X. Feng et al., 2015. Effects of 2, 5-hexanedione on angiogenesis and vasculogenesis in chick embryos. Reproductive Toxicol., 51: 79-89.
    CrossRef  |  Direct Link  |  
  8. Zhang, Q.Q., Y. Ding, Y. Lei, C.L. Qi and X.D. He et al., 2014. Andrographolide suppress tumor growth by inhibiting TLR4/NF-κB signaling activation in insulinoma. Int. J. Biol. Sci., 10: 404-414.
    CrossRef  |  Direct Link  |  
  9. Zhang, Q.Q., D.L. Zhou, Y. Ding, H.Y. Liu and Y. Lei et al., 2014. Andrographolide inhibits melanoma tumor growth by inactivating the TLR4/NF-κB signaling pathway. Melanoma Res., 24: 545-555.
    CrossRef  |  Direct Link  |  
  10. Wang, X.Y., Y. Li, G. Wang, L.J. Wang and A. Munsterberg et al., 2014. Combinational electroporation and transplantation approach to studying gene functions in avian embryos. Chin. Sci. Bull., 59: 616-624.
    CrossRef  |  Direct Link  |  
  11. Qi, C., Q. Zhou, B. Li, Y. Yang and L. Cao et al., 2014. Glipizide, an antidiabetic drug, suppresses tumor growth and metastasis by inhibiting angiogenesis. Oncotarget, 5: 9966-9979.
    Direct Link  |  
  12. Ma, Z.L., G. Wang, X. Cheng, M. Chuai, H. Kurihara, K.K.H. Lee and X. Yang, 2014. Excess caffeine exposure impairs eye development during chick embryogenesis. J. Cell. Mol. Med., 18: 1134-1143.
    CrossRef  |  Direct Link  |  
  13. Lu, W.H., G. Wang, Y. Li, S. Li and X.Y. Song et al., 2014. Autophagy functions on EMT in gastrulation of avian embryo. Cell Cycle, 13: 2752-2764.
    CrossRef  |  Direct Link  |  
  14. Li, Y., X.Y. Wang, Z.L. Zhang, X. Cheng and X.D. Li et al., 2014. Excess ROS induced by AAPH causes myocardial hypertrophy in the developing chick embryo. Int. J. Cardiol., 176: 62-73.
    CrossRef  |  Direct Link  |  
  15. Li, Y., X.Y. Wang, Z.L. Ma, M. Chuai, A. Munsterberg, K.K.H. Lee and X. Yang, 2014. Endoderm contributes to endocardial composition during cardiogenesis. Chin. Sci. Bull., 59: 2749-2755.
    CrossRef  |  Direct Link  |  
  16. He, Y.Q., Y. Li, X.Y. Wang, X.D. He and L. Jun et al., 2014. Dimethyl phenyl piperazine iodide (DMPP) induces glioma regression by inhibiting angiogenesis. Exp. Cell Res., 320: 354-364.
    CrossRef  |  Direct Link  |  
  17. Cheng, X., J.L. Chen, Z.L. Zhang, Z.L. Ma and S. Lv et al., 2014. Biphasic influence of dexamethasone exposure on embryonic vertebrate skeleton development. Toxicol. Applied Pharmacol., 281: 19-29.
    CrossRef  |  Direct Link  |  
  18. Cheng, X., G. Wang, K.K.H. Lee and X. Yang, 2014. Dexamethasone use during pregnancy: Potential adverse effects on embryonic skeletogenesis. Curr. Pharm. Design, 20: 5430-5437.
    Direct Link  |  
  19. Chen, Y., G. Wang, Z.L. Ma, Y. Li and X.Y. Wanget al., 2014. Adverse effects of high glucose levels on somite and limb development in avian embryos. Food Chem. Toxicol., 71: 1-9.
    CrossRef  |  Direct Link  |  
  20. Chen, Y., G. Wang, X.Y. Wang, Z.L. Ma and Y.P. Chen et al., 2014. Effects of high salt-exposure on the development of retina and lens in 5.5-day chick embryo. Cell Physiol. Biochem., 34: 804-817.
    Direct Link  |  
  21. Zhou, Q., C.L. Qi, Y. Li, X.D. He and J.C. Li et al., 2013. A novel four-step system for screening angiogenesis inhibitors. Mol. Med. Rep., 8: 1734-1740.
    Direct Link  |  
  22. Wang, G., Y. Li, X.Y. Wang, Z. Han and M. Chuai et al., 2013. Slit/Robo1 signaling regulates neural tube development by balancing neuroepithelial cell proliferation and differentiation. Exp. Cell Res., 319: 1083-1093.
    CrossRef  |  
  23. Tan, R.R., Y.F. Li, X.T. Zhang, Y.H. Huang and Y.P. Wu et al., 2013. Glucose metabolism disorder is a risk factor in ethanol exposure induced malformation in embryonic brain. Food Chem. Toxicol., 60: 238-245.
    CrossRef  |  
  24. Li, Y., X.Y. Wang, T. Wu, M. Chuai, K.K.H. Lee, L.J. Wang and X. Yang, 2013. PTEN is involved in modulation of vasculogenesis in early chick embryos. Biol. Open, 2: 587-595.
    CrossRef  |  Direct Link  |  
  25. Li, P., W.J. Zhu, Z.L. Ma, G. Wang and H. Peng et al., 2013. Enhanced beta-catenin expression and inflammation are associated with human ectopic tubal pregnancy. Hum. Reprod., 28: 2363-2371.
    CrossRef  |  Direct Link  |  
  26. Li, P., W.J. Zhu, K.K.H. Lee and X. Yang, 2013. Reply: The inflammatory regulation of tubal β-catenin expression in human ectopic pregnancy: Is it too early to propose a cause-and-effect relationship? Hum. Reprod., 28: 3381-3381.
    Direct Link  |  
  27. Jin, Y.M., S.Z. Zhao , Z.L. Zhang, Y. Chen and X. Cheng et al., 2013. High glucose level induces cardiovascular dysplasia during early embryo development. Exp. Clin. Endocrinol. Diabetes, 121: 448-454.
    PubMed  |  
  28. He, R.R., Y. Li, X.D. Li, R.N. Yi and X.Y. Wang et al., 2013. A new oxidative stress model, 2, 2-Azobis (2-Amidinopropane) dihydrochloride induces cardiovascular damages in chicken embryo. PloS One, Vol. 8. 10.1371/journal.pone.0057732.
    CrossRef  |  
  29. Chen, Y., J.X. Fan, Z.L. Zhang, G. Wang and X. Cheng et al., 2013. The negative influence of high-glucose ambience on neurogenesis in developing quail embryos. PLOS One, Vol. 8. 10.1371/journal.pone.0066646.
    CrossRef  |  
  30. Chen, E., M.K. Tang, Y. Yao, W.W.Y. Yau and L.M. Lo et al., 2013. Silencing BRE expression in human umbilical cord perivascular (HUCPV) progenitor cells accelerates osteogenic and chondrogenic differentiation. PloS One, Vol. 8. 10.1371/journal.pone.0067896.
    CrossRef  |  
  31. Wang, X.Y., Y. Li, Z.L. Ma, L.J. Wang and M. Chuai et al., 2012. Retention of stem cell plasticity in avian primitive streak cells and the effects of local microenvironment. Anatomical Rec., 296: 533-543.
    CrossRef  |  
  32. Nelson, S.A., Z. Li, I.P. Newton, D. Fraser and R.E. Milne et al., 2012. Tumorigenic fragments of APC cause dominant defects in directional cell migration in multiple model systems. Dis. Models Mechanisms, 5: 940-947.
    Direct Link  |  
  33. Ma, Z.L., Y. Qin, G. Wang, X.D. Li and R.R. He et al., 2012. Exploring the caffeine-induced teratogenicity on neurodevelopment using early chick embryo. Plos One, Vol. 7. 10.1371/journal.pone.0034278.
    CrossRef  |  
  34. Li, X.D., R.R. He, Y. Qin, B. Tsoi, Z.L. Ma, X. Yang and H. Kurihara, 2012. The effects of caffeine on the development of serotonergic system in chicken embryo. Food Chem. Toxicol., 50: 1848-1853.
  35. Cheng, X., G. Wang, Z.L. Ma, Y.Y. Chen and J.J. Fan et al., 2012. Exposure to 2,5-hexanedione can induce neural malformations in chick embryos. Neurotoxicology, 33: 1239-1247.
    CrossRef  |  
  36. Zhou, W.J., Z.H. Geng, S. Chi, W. Zhang and X.F. Niu et al., 2011. Slit-Robo signaling induces malignant transformation through Hakai-mediated E-cadherin degradation during colorectal epithelial cell carcinogenesis. Cell Res., 21: 609-626.
    CrossRef  |  
  37. Wang, L.J., X. Zhou, W. Wang, F. Tang and C.L. Qi et al., 2011. Andrographolide inhibits oral squamous cell carcinogenesis through NF-κB inactivation. J. Dent Res., 90: 1246-1252.
    CrossRef  |  
  38. Lu, X., S. Chen, L. Yang, X. Zha, X. Yang and Y. Li, 2011. The expression pattern of CD3 chain genes in fetal/maternal interface. Hematology, 16: 185-189.
    CrossRef  |  PubMed  |  
  39. Lu, X., F. Lin, H. Fang, X. Yang and L. Qin, 2011. Expression of a putative stem cell marker Musashi-1 in endometrium. Histol. Histopathol., 26: 1127-1133.
    PubMed  |  
  40. Davidson, L., H. Maccario, N.M. Perera, X. Yang and L. Spinelli et al., 2010. Suppression of cellular proliferation and invasion by the concerted lipid and protein phosphatase activities of PTEN. Oncogene, 29: 687-697.
    CrossRef  |  
  41. He, R.R., N. Yao, M. Wang, X. Yang and C.C. Yau et al., 2009. Effects of histamine on lipid metabolic disorder in mice loaded with restraint stress. J. Pharmacol. Sci., 111: 117-123.
    Direct Link  |  
  42. Yue, Q., L. Wagstaff, X. Yang, C. Weijer and A. Munsterberg, 2008. Wnt3a-mediated chemorepulsion controls movement patterns of cardiac progenitors and requires RhoA function. Development, 135: 1029-1037.
    CrossRef  |  
  43. Yang, X., H. Chrisman and C.J. Weijer, 2008. PDGF signaling controls the migration of mesoderm cells during chick gastrulation by regulating N-cadherin expression. Development, 135: 3521-3530.
    CrossRef  |  PubMed  |  
  44. Leslie, N.R., X. Yang, C.P. Downes and C.J. Weijer, 2007. PtdIns(3,4,5)P(3)-dependent and-independent roles for PTEN in the control of cell migration. Curr. Biol., 17: 115-125.
  45. Iimura, T., X. Yang, C.J. Weijer and O. Pourquie, 2007. Dual mode of paraxial mesoderm formation during chick gastrulation. Proc. Nat. Acad. Sci., 104: 2744-2749.
  46. Chuai, M., W. Zeng, X. Yang, V. Boychenko, J. Glazier and C.J. Weijer, 2006. Cell movement during chick primitive streak formation. Dev. Biol., 296: 137-149.
    Direct Link  |  
  47. Leslie, N.R., X. Yang, C.P. Downes and C.J. Weijer, 2005. The regulation of cell migration by PTEN. Biochem. Soc. Trans., 33: 1507-1508.
    Direct Link  |  
  48. Cui, C., X. Yang, M. Chuai, J.A. Glazier and C.J. Weijer, 2005. Analysis of tissue flow patterns during primitive streak formation in the chick embryo. Dev. Biol., 284: 37-47.
    CrossRef  |  
  49. Yang, X., D. Dormann, A.E. Munsterberg and C.J. Weijer, 2002. Cell movement patterns during gastrulation in the chick are controlled by positive and negative chemotaxis mediated by FGF4 and FGF8. Dev. Cell, 3: 425-437.
    PubMed  |  
  50. Szalmay, G., G. Varga, F. Kajiyama, X.S. Yang, T.F. Lang, R.M. Case and M.C. Steward, 2001. Bicarbonate and fluid secretion evoked by cholecystokinin, bombesin and acetylcholine in isolated guinea-pig pancreatic ducts. J. Physiol., 535: 795-807.
    CrossRef  |  
  51. Bruce, J.I., X. Yang, C.J. Ferguson, A.C. Elliott, M.C. Steward, R.M. Case and D. Riccardi, 1999. Molecular and functional identification of a Ca2+ (polyvalent cation)-sensing receptor in rat pancreas. J. Biol. Chem., 274: 20561-20568.
    Direct Link  |  
  52. Yang, X.S. and K. Kamino, 1997. Photometric assessment of volume changes coupled with membrane potential in valinomycin-incorporated red blood cells. Japanese J. Physiol., 47: 217-230.
    CrossRef  |  
  53. Momose-Sato, Y., K. Sato, A. Hirota, T. Sakai, X.S. Yang and K. Kamino, 1997. Optical Characterization of a novel GABA response in early embryonic chick brainstem. Neuroscience, 80: 203-219.
    CrossRef  |  
  54. Yang, X.S. and K. Kamino, 1995. Photometric determination of phenomenological correlation between osmotic behavior and hemolysis of red blood cells. Japanese J. Physiol., 45: 723-741.
    CrossRef  |