Hi, I am Xianbin Yang, My LiveDNA is 86.6312
 
   
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Dr. Xianbin Yang
 
Highest Degree: Ph.D. in Bioorganic Chemistry from Polish Academy of Sciences, Poland
 
Institute: University of Houston at Clear Lake, USA
 
Area of Interest: Chemistry
  •   Magnetic Resonance
  •   Organic Chemistry
  •   Pharmaceutical Sciences
  •   Nucleic Acids Research
 
URL: http://livedna.org/86.6312
 
My SELECTED Publications
1:   Bowick, G.C., S.M. Fennewald, L.H. Zhang, X.B. Yang and J.F. Aronson et al., 2009. Attenuated and lethal variants of Pichinde virus induce differential patterns of NF-κB activation suggesting a potential target for novel therapeutics. Viral Immunol., 22: 457-462.
PubMed  |  
2:   Fennewald, S.M., E.P. Scott, L.H. Zhang, X.B. Yang and J.F.Aronson et al., 2007. Thioaptamer decoy targeting of AP-1 proteins influences cytokine expression and the outcome of arenavirus infections. J. Gen. Virol., 88: 981-990.
PubMed  |  
3:   Ferguson, M.R., D.R. Rojo, A. Somasunderam, V. Thiviyanathan, B.D. Ridley, X.B. Yang and D.G. Gorenstein, 2006. Delivery of double-stranded DNA thioaptamers into HIV-1 infected cells for antiviral activity. Biochem. Biophys. Res. Commun., 344: 792-797.
CrossRef  |  PubMed  |  Direct Link  |  
4:   Gao, C.Y., H. Qiao, L.T. Ma, X.B. Yang, L.J. Dong and L. Zhang, 1990. NMR study on fluoroisonucleosides (I): Determination of the configuration and conformation of 1'-a-methoxy-2'-deoxy-2'-B-ruoro-2'-a-uracil -3,4'-o-lsopropylidene-L-arabinoside. Chem. Res. Chinese Univ., 6: 225-228.
Direct Link  |  
5:   Hecht, A.H., G.J. Sommer, R.H. Durland, X. Yang, A.K. Singh and A.V. Hatch, 2010. Aptamers as affinity reagents in an integrated electrophoretic lab-on-a-chip platform. Anal. Chem., 82: 8813-8820.
CrossRef  |  PubMed  |  Direct Link  |  
6:   Jiang, T., M.F. Hong, J.X. Pan and X.B. Yang, 1992. NMR study of two new compounds from the roots of Zanthoxylum Schinifolium Sieb, Et Zucc. Chinese J. Mag. Res., 9: 413-417.
7:   Jiang, T., S. Peng, X.B. Yang and Z.L. Zhang, 1991. Study on 1H NMR and stereochemistry of indoloquinolizine derivatives. Chinese J. Mag. Res., 8: 317-414.
8:   Jiang, T., Z.L. Zhang, X.B. Yang and J. Min, 1991. Study on NMR and structure of 8,2'-O-cyclo Ara-A. Chinese J. Mag. Res., 8: 173-177.
9:   Leary, J.F., L.M. Reece, X.B. Yang and D.G. Gorenstein, 2005. High-Throughput flow-cytometric screening of combinatorial bead libraries for proteomics and drug discovery. Proceedings of the Advanced Biomedical and Clinical Diagnostic Systems III, April 11, 2005, Bellingham, WA., USA., pp: 216-223.
10:   Ma, L.T., X.B. Yang, L.J. Dong and L. Zhang, 1990. Synthesis of methyl 2'-deoxy-2'-fluoro 2'-uracil-3',4'-O-isopropylidene-L-arabinoside. Chinese J. Org. Chem., 10: 233-236.
11:   Ma, Y., G.Q. Han, T. Jiang and X.B. Yang, 1992. Neolignans from Piper Kadsura (II). Chinese Chem. Lett., 3: 635-636.
12:   Pan, J.X., H. Zhang, X.B. Yang and M.F. Hong, 1995. Bioflavones from the Testa of Ginkgo Biloba. L. J. Plant Resour. Environ., 4: 17-21.
13:   Potrzebowski, M.J., X.B. Yang, K. Misiura, W.R. Majzner and M.W. Wieczorek et al., 2001. Synthesis and structural studies of SP and RP diastereomers of deoxyxylothymidyl-3'-O-acetylthymidyl (3',5')-O-(2-Cyanoethyl)phosphorothioate in solution and in the solid state. Eur. J. Org. Chem., 2001: 1491-1501.
CrossRef  |  Direct Link  |  
14:   Qiao, L., L. Huang, C.Y. Gao, Y.Y. Zhao, X.B. Yang and L. Zhang, 1994. The NMR studies on alkaloids in Sophora Flavescence Ait. J. Beijing Med. Univ., 26: 485-486.
15:   Sierant, M., X.B. Yang and B. Nawrot, 2013. SiRNA analogs containing phosphorodithioate substitutions. Phosphorus Sulfur Silicon Relat. Elem., 188: 427-436.
CrossRef  |  Direct Link  |  
16:   Sierant, M., X.B. Yang, M. Janicka, N. Li, C. Martinez, T. Hassell and B. Nawrot, 2011. SiRNA with phosphorodithioate modification. Proceedings of the 15th Symposium on Chemistry of Nucleic Acid Compounds, June 5-10, 2011, Czeck Republic, pp: 135-139.
17:   Su, J., X.B. Yang, L.X. Wang and L. Zhang, 1996. (Sp)-O-ocetyl-8-chloroadenosine 3',5'-cyclophosphate induced differentiation on human Leukemia HL-60 cells. Acta Pharmaceutica Sinica, 31: 641-646.
18:   Volk, D.E., X. Yang, S.M. Fennewald, D.J. King and S.E. Bassett et al., 2002. Solution structure and design of dithiophosphate backbone aptamers targeting transcription factor NF-κB. Bioorg. Chem., 30: 396-419.
CrossRef  |  PubMed  |  Direct Link  |  
19:   Wang, B., K. Zou, X.B. Yang, Y.Y. Zhao and R.Y. Zhang, 1997. Two new flavanone glycosides from Glycyrrhizia inflate. Acta Pharmaceutica Sinica, 32: 199-202.
PubMed  |  
20:   Wang, C.G., L.X. Wang, T.Y. Jiang, X.B. Yang and L. Zhang, 1993. 3',5'-/2',5'-linked di-and triadenylyl methylphosphonates synthesis and P-configuration study using 1H NMR and 31P NMR. Chinese J. Org. Chem., 13: 301-302.
21:   Wang, C.G., L.X. Wang, X.B. Yang, T. Jiang and L. Zhang, 1993. Synthesis of (3',5'), (2',5')-linked di- and triadenylyl methylphosphonate analogues. Nucleic Acids Res., 21: 3245-3248.
22:   Wang, H., X.B. Yang, N.K. Herzog, B.A. Luxon, L.O. Lomas and D.G. Gorenstein, 2006. Identification of proteins bound to specific thioaptamer from crude nuclear extracts by SELDI on-chip analysis. Biochem. Biophys. Res. Commun., 347: 586-593.
23:   Wang, J.L., C.S. Yang, R.N. Yan, B. Yao and X.B. Yang, 1994. Studies on sesquiterpene lactones from Illicium minwanense B.N. Chang Et S.D. Zhang. Acta Pharmaceutica Sinica, 29: 693-696.
24:   Yang, X., S. Fennewald, B.A. Luxon, J. Aronson, N.K. Herzog and D.G. Gorenstein, 1999. Aptamers containing thymidine 3'-O-phosphorodithioates: Synthesis and binding to nuclear factor-κB. Bioorg. Med. Chem. Lett., 9: 3357-3362.
CrossRef  |  PubMed  |  Direct Link  |  
25:   Yang, X., S.E. Bassett, X. Li, B.A. Luxon and N.K. Herzog, 2002. Construction and selection of bead-bound combinatorial oligonucleoside phosphorothioate and phosphorodithioate aptamer libraries designed for rapid PCR-based sequencing. Nucleic Acids Res., Vol. 30. .
PubMed  |  
26:   Yang, X.B. and B. Cheng, 1991. The application of modern NMR techniques in biomedical sciences. J. Beijing Med. Univ., 23: 75-77.
27:   Yang, X.B. and D.G. Gorenstein, 2004. Progress in thioaptamer development. Curr. Drug Targets, 5: 705-715.
CrossRef  |  PubMed  |  
28:   Yang, X.B. and E. Mierzejewski, 2010. Synthesis of nucleoside and oligonucleoside dithiophosphates. New J. Chem., 34: 805-819.
29:   Yang, X.B., 2008. Thiophosphoramidites scale up and their use in the synthesis of phosphorodithioate linkages. Nucl. Acids Symp. Ser., 52: 341-341.
Direct Link  |  
30:   Yang, X.B., A. Sierzchala, K. Misiura, W. Niewiarowski, M. Sochacki, W.J. Stec and M.W. Wieczorek, 1998. The first stereocontrolled solid-phase synthesis of Di-,Tri-and tetra[adenosine (2',5') phosphorothioate]s. J. Org. Chem., 63: 7097-7100.
PubMed  |  
31:   Yang, X.B., D. Beasley, J. Engelhardt, M. Shumbera, B.A. Luxon and D.G. Gorenstein, 2008. Bead-Based approaches to develop thioaptamers for diagnostics and therapeutics. Phosphorus Sulfur Silicon Relat. Elem., 183: 469-472.
CrossRef  |  Direct Link  |  
32:   Yang, X.B., H. Wang, D. Beasley, D. Volk and X. Zhao et al., 2006. Selection of thioaptamers for diagnostics and therapeutics. Ann. N. Y. Acad. Sci., 1082: 116-119.
CrossRef  |  PubMed  |  Direct Link  |  
33:   Yang, X.B., K. Misiura and W.J. Stec, 1999. Reactivity of nucleoside 5'-O-phosphates,-phosphorothioates,-methanephosphonates and-methanephosphonothioates toward activated xylonucleosides. Heteroatom Chem., 10: 91-104.
CrossRef  |  Direct Link  |  
34:   Yang, X.B., K. Misiura, M. Sochacki and W.J. Stec, 1997. Deoxyxylothymidine 3'-O-phosphorothioates: Synthesis, stereochemistry and stereocontrolled incorporation into oligothymidylates. Bioorg. Med. Chem. Lett., 7: 2651-2656.
35:   Yang, X.B., K. Misiura, W.J. Stec, M.J. Potrzebowski and S. Kazmierski et al., 2000. Nucleophilic N1->N3 rearrangement of 5'-O-trityl-O2,3'-cycloanhydrothymidine. Nucleosides Nucleotides Nucleic Acids, 19: 1657-1673.
CrossRef  |  PubMed  |  Direct Link  |  
36:   Yang, X.B., K. Zou, B. Yao and R. Zhang, 1994. NMR study of inflacoumarin A. Bopuxue Zazhi. Chinese J. Mag. Res., 11: 399-403.
37:   Yang, X.B., M. Guo, T. Jiang, B. Yao and S. Peng, 1993. The studies on 1H NMR and stereochemistry of Nb-methyl-tetrahydroharman. Chinese J. Magn. Reson., 10: 149-156.
38:   Yang, X.B., M. Sierant, M. Janicka, L. Peczek and C. Martinez et al., 2012. Gene silencing activity of siRNA molecules containing phosphorodithioate substitutions. ACS Chem. Biol., 7: 1214-1220.
CrossRef  |  PubMed  |  Direct Link  |  
39:   Yang, X.B., N. Li and D. Gorenstein, 2011. Strategies for the discovery of therapeutic aptamers. Expert Opin. Drug Discov., 6: 75-87.
CrossRef  |  PubMed  |  
40:   Yang, X.B., R.P. Hodge, B.A. Luxon, R. Shope and D.G. Gorenstein, 2002. Separation of synthetic oligonucleotide dithioates from monothiophosphate impurities by anion-exchange chromatography on a mono-q column. Anal. Biochem., 306: 92-99.
CrossRef  |  PubMed  |  Direct Link  |  
41:   Yang, X.B., S. Peng, T. Jiang and Z.L. Zhang, 1991. The study on 1H NMR and stereochemistry of tetrahydro-β-carbolines. Chinese J. Mag. Res., 8 : 317-326.
42:   Yang, X.B., S.M. Zhang, B.A. Luxon and D.G. Gorenstein, 1999. Measurement of 3JH3'-P with Watergate. NMR Newsletter, 495: 25-27.
43:   Yang, X.B., T. Jiang, S. Peng and L. Zhang, 1992. The study on 13C NMR of tetrahydro-β-carbolines. Chinese J. Mag. Res., 9: 183-188.
44:   Yang, X.B., X. Chen, C.U. Wang and L. Zhang, 1993. Studies on the stereochemistry of adenosine 3',5'-cycloalkyl phosphonate. Chem. J. Chinese Univ., 14: 795-800.
45:   Yang, X.B., X. Li, T.W. Prow, L.M. Reece and S.E. Bassett et al., 2003. Immunofluorescence assay and flow-cytometry selection of bead-bound aptamers. Nucleic Acids Res., Vol. 31. .
PubMed  |  
46:   Yang, X.B., X.F. Pei, T. Jiang and J. Shen, 1992. The configuration of 6-chloro nitrile epimers of tropane derivatives. Chinese Sci. Bull., 37: 1213-1216.
47:   Yang, X.B., X.F. Pei, T. Jiang and J.X. Shen, 1993. NMR studies on the configuration of 6-chloro nitrile epimers of tropane derivatives. Chinese Sci. Bull., 38: 91-495.
48:   Zhang, L., S.Q. Peng and X.B. Yang, 1994. Study on the 1H NMR and stereochemistry of substituted tetrahydro-β-carbolines. Chinese J. Mag. Res., 11: 287-294.
49:   Zhang, R.Y., X.K. Chen, X.B. Yang, L. Tan and W.Y. He, 1994. The structures of saikosaponin M and N from Bupleurum smithii wolff. Acta Pharmaceutica Sinica, 29: 684-688.
50:   Zhang, S., X.B. Yang and D.G. Gorenstein, 2000. Enhanced suppression of residual water in a 270 WET sequence. J. Mag. Reson., 143: 382-386.
CrossRef  |  PubMed  |  Direct Link  |  
51:   Zhang, S., X.B. Yang and D.G. Gorenstein, 2002. Suppression of linearly responsive residual water. Concepts Mag. Reson., 14: 102-111.
CrossRef  |  Direct Link  |  
52:   Zhou, L., S. Lin, X.B. Yang and J. Zhuo, 1996. Diagnostic value of serum phosphorus nuclear magnetic resonance spectroscopy (31P NMR) in gastric cancer. Chinese J. Dig., 16: 35-38.
53:   Zou, K., R.Y. Zhang and X.B. Yang, 1994. Structure determination of inflacoumarin A from Glycyrrhiza. Acta Pharmaceutica Sinica, 29: 397-399.