Hi, I am Rui-An Wang, My LiveDNA is 86.6315
 
   
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Dr. Rui-An Wang
 
Highest Degree: Post Doctoral Fellow in Pathology from University of Texas MD Anderson Cancer Center, USA
 
Institute: Shenzhen Hospital of Southern Medical University, China
 
Area of Interest: Biomedical Sciences
  •   Breast Cancer
  •   Endocrinology
  •   Metastasis
  •   Carcinogenesis
 
URL: http://livedna.org/86.6315
 
My SELECTED Publications
1:   Bagheri-Yarmand, R., A.H. Talukder, R.A. Wang, R.K. Vadlamudi and R. Kumar, 2004. Metastasis-associated protein 1 deregulation causes inappropriate mammary gland development and tumorigenesis. Development, 131: 3469-3479.
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2:   Bagheri-Yarmand, R., R.K. Vadlamudi, R.A. Wang, J. Mendelsohn and R. Kumar, 2000. Vascular endothelial growth factor up-regulation via p21-activated kinase-1 signaling regulates heregulin-beta1-mediated angiogenesis. J. Biol. Chem., 275: 39451-39457.
PubMed  |  
3:   Balasenthil, S., A.A. Sahin, C.J. Barnes, R.A. Wang, R.G. Pestell, R.K. Vadlamudi and R. Kumar, 2004. p21-activated kinase-1 signaling mediates cyclin D1 expression in mammary epithelial and cancer cells. J. Biol. Chem., 279: 1422-1428.
PubMed  |  
4:   Bao, W., H.J. Fu, Q.S. Xie, L. Wang and R. Zhang et al., 2011. HER2 interacts with CD44 to up-regulate CXCR4 via epigenetic silencing of microRNA-139 in gastric cancer cells. Gastroenterology, 141: 2076-2087.
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5:   Dong, L., Y. Li, J. Cao, F. Liu and E. Pier et al., 2012. FGF2 regulates melanocytes viability through the STAT3-transactivated PAX3 transcription. Cell Death Different., 19: 616-622.
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6:   Hu, J., Y.Q. Zhang, X.P. Liu, R.A. Wang, Y. Jin and R.J. Xu, 2003. Expression and localization of Smad1, Smad2 and Smad4 proteins in rat testis during postnatal development. Asian J. Androl., 5: 51-56.
7:   Kumar, R. and R.A. Wang, 2002. Protein kinases in mammary gland development and cancer. Microsc. Res. Tech., 59: 49-57.
8:   Kumar, R., R.A. Wang and C.J. Barnes, 2004. Coregulators and chromatin remodeling in transcriptional control. Mol. Carcinogen., 41: 221-230.
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9:   Kumar, R., R.A. Wang and R. Bagheri-Yarmand, 2003. Emerging roles of MTA family members in human cancers. Semin. Oncol., 30: 30-37.
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10:   Kumar, R., R.A. Wang, A. Mazumdar, A.H. Talukder and M. Mandal et al., 2002. A naturally occurring MTA1 variant sequesters oestrogen receptor-α in the cytoplasm. Nature, 418: 654-657.
CrossRef  |  
11:   Li, W., W. Bao, J. Ma, X. Liu, R. Xu, R.A. Wang and Y. Zhang, 2008. Metastasis tumor antigen 1 is involved in the resistance to heat stress-induced testicular apoptosis. FEBS Lett., 582: 869-873.
CrossRef  |  
12:   Liu, F., J. Cao, J. Lv, L. Dong and E. Pier et al., 2013. TBX2 expression is regulated by PAX3 in the melanocyte lineage. Pigment Cell Melanoma Res., 26: 67-77.
CrossRef  |  
13:   Liu, H.T., F. Li, W.Y. Wang, X.J. Li and Y.M. Liu et al., 2010. Rapamycin inhibits re-endothelialization after percutaneous coronary intervention by impeding the proliferation and migration of endothelial cells and inducing apoptosis of endothelial progenitor cells. Texas Heart Inst. J., 37: 194-201.
14:   Manavathi, B., S. Peng, S.K. Rayala, A.H. Talukder and M.H. Wang et al., 2007. Repression of Six3 by a corepressor regulates rhodopsin expression. Proc. Natl. Acad. Sci., 104: 13128-13133.
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15:   Manavathi, B., S.S. Nair, R.A. Wang, R. Kumar and R.K. Vadlamudi, 2005. Proline-, glutamic acid-and leucine-rich protein-1 is essential in growth factor regulation of signal transducers and activators of transcription 3 activation. Cancer Res., 65: 5571-5577.
CrossRef  |  
16:   Mandal, M., R. Vadlamudi, D. Nguyen, R.A. Wang and L. Costa et al., 2001. Growth factors regulate heterogeneous nuclear ribonucleoprotein K expression and function. J. Biol. Chem., 276: 9699-9704.
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17:   Mazumdar, A., R.A. Wang, S.K. Mishra, L. Adam and R. Bagheri-Yarmand et al., 2000. Transcriptional repression of oestrogen receptor by metastasis-associated protein 1 corepressor. Nat. Cell Biol., 3: 30-37.
CrossRef  |  
18:   Mishra, S.K., A. Mazumdar, R.K. Vadlamudi, F. Li and R.A. Wang et al., 2003. MICoA, a novel metastasis-associated protein 1 (MTA1) interacting protein coactivator, regulates estrogen receptor-α transactivation functions. J. Biol. Chem., 278: 19209-19219.
CrossRef  |  
19:   Pakala, S.B., S.K. Rayala, R.A. Wang, K. Ohshiro and P. Mudvari et al., 2013. MTA1 promotes STAT3 transcription and pulmonary metastasis in breast cancer. Cancer Res., 10.1158/0008-5472.CAN-12-3998.
CrossRef  |  
20:   Rayala, S.K., A.H. Talukder, S. Balasenthil, R. Tharakan and C.J. Barnes et al., 2006. P21-activated kinase 1 regulation of estrogen receptor-alpha activation involves serine 305 activation linked with serine 118 phosphorylation. Cancer Res., 66: 1694-1701.
PubMed  |  
21:   Rayala, S.K., P. den Hollander, S. Balasenthil, P.R. Molli and A.J. Bean et al., 2006. Hepatocyte growth factor-regulated tyrosine kinase substrate (HRS) interacts with PELP1 and activates MAPK. J. Biol. Chem., 281: 4395-4403.
CrossRef  |  
22:   Vadlamudi, R.K., A.A. Sahin, L. Adam, R.A. Wang and R. Kumar, 2003. Heregulin and HER2 signaling selectively activates c-Src phosphorylation at tyrosine 215. FEBS Lett., 543: 76-80.
23:   Vadlamudi, R.K., L. Adam, R.A. Wang, M. Mandal and D. Nguyen et al., 2000. Regulatable expression of p21-activated kinase-1 promotes anchorage-independent growth and abnormal organization of mitotic spindles in human epithelial breast cancer cells. J. Biol. Chem., 275: 36238-36244.
PubMed  |  
24:   Vadlamudi, R.K., R.A. Wang, A. Mazumdar, Y. Kim, J. Shin, A. Sahin and R. Kumar, 2001. Molecular cloning and characterization of PELP1, a novel human coregulator of estrogen receptor α. J. Biol. Chem., 276: 38272-38279.
CrossRef  |  
25:   Vadlamudi, R.K., R.A. Wang, A.H. Talukder, L. Adam, R. Johnson and R. Kumar, 2000. Evidence of Rab3A expression, regulation of vesicle trafficking and cellular secretion in response to heregulin in mammary epithelial cells. Mol. Cell. Biol., 20: 9092-9101.
CrossRef  |  
26:   Wang, L., X. Zhang, L.T. Jia, S.J. Hu and J. Zhao et al., 2013. C-Myc-mediated epigenetic silencing of microRNA-101 contributes to dysregulation of multiple pathways in hepatocellular carcinoma. Hepatology, 10.1002/hep.26720.
CrossRef  |  
27:   Wang, R.A. and G.Q. Zhao, 1999. Transforming growth factor β signal transducer Smad2 is expressed in mouse meiotic germ cells, Sertoli cells and Leydig cells during spermatogenesis. Biol. Reprod., 61: 999-1004.
CrossRef  |  
28:   Wang, R.A. and Q.G. Yan, 2013. Molecular Adaptation of Cancer Cells. In: Adaptation Biology and Medicine: New Developments, Popescu, L.M., A.R. Hargens and P.K. Singal (Eds.). Narosa Publishing House, New Delhi, India, pp: 131-138.
29:   Wang, R.A., A. Mazumdar, R.K. Vadlamudi and R. Kumar, 2003. P21-activated kinase-1 phosphorylates and transactivates estrogen receptor-alpha and promotes hyperplasia in mammary epithelium. EMBO. J., 21: 5437-5447.
PubMed  |  
30:   Wang, R.A., H. Zhang, S. Balasenthil, D. Medina and R. Kumar, 2006. PAK1 hyperactivation is sufficient for mammary gland tumor formation. Oncogene, 25: 2931-2936.
PubMed  |  
31:   Wang, R.A., M. Zhao, M.L. Meistrich and R. Kumar, 2005. Stage-specific expression of dynein light chain-1 and its interacting kinase, p21-activated kinase-1, in rodent testes: Implications in spermiogenesis. J. Histochem. Cytochem., 53: 1235-1243.
PubMed  |  
32:   Wang, R.A., P.K. Nakane and T. Koji, 1998. Autonomous cell death of mouse male germ cells during fetal and postnatal period. Biol. Reprod., 58: 1250-1256.
CrossRef  |  
33:   Wang, R.A., Q.L. Li, Z.S. Li, P.J. Zheng and H.Z. Zhang et al., 2013. Apoptosis drives cancer cells proliferate and metastasize. J. Cell. Mol. Med., 17: 205-211.
CrossRef  |  
34:   Wang, R.A., R.K. Vadlamudi, R.B. Yarmand, I. Beuvink, N.E. Hynes and R. Kumar, 2003. Essential functions of p21-activated kinase 1 in morphogenesis and differentiation of mammary glands. J. Cell Biol., 161: 583-592.
PubMed  |  
35:   Wang, R.A., Z.S. Li, H.Z. Zhang, P.J. Zheng and Q.L. Li et al., 2013. Invasive cancers are not necessarily from preformed in situ tumours-an alternative way of carcinogenesis from misplaced stem cells. J. Cell. Mol. Med., 17: 921-926.
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36:   Wang, R.A., Z.S. Li, Q.G. Yan, X.W. Bian and Y.Q. Ding et al., 2013. Resistance to apoptosis should not be taken as a hallmark of cancer. Chin. J. Cancer, 10.5732/cjc.013.10131.
CrossRef  |  
37:   Wu, J., F. Dong, R.A. Wang, J. Wang and J. Zhao et al., 2013. Central role of cellular senescence in TSLP-induced airway remodeling in asthma. PloS One, Vol. 8. 10.1371/journal.pone.0077795.
CrossRef  |  
38:   Zhang, F., J. Ye, Z. Li, R. Wang and J. Zhang et al., 2008. Random versus non-random DNA strand segregation difference between cancer and normal stem cells might provide an opportunity to specific targeting the former by radiotherapy. Cell Cycle, 7: 3282-3282.
Direct Link  |  
39:   Zhang, Y., Q. Li, F. Zhu, J. Cui and K. Li et al., 2009. Subcellular localization of APMCF1 and its biological significance of expression pattern in normal and malignant human tissues. J. Exp. Clin. Cancer Res., Vol. 28. 10.1186/1756-9966-28-111.
CrossRef  |  
40:   Zhang, Y.Q., X.Z. He, J.S. Zhang, R.A. Wang, J. Zhou and R.J. Xu, 2004. Stage-specific localization of transforming growth factor 1 and 3 and their receptors during spermatogenesis in men. Asian J. Androl., 6: 105-109.
Direct Link  |  
41:   Zhao, Y., W.G. Hou, H.P. Zhu, J. Zhao, R.A. Wang, R.J. Xu and Y.Q. Zhang, 2008. Expression of thyrotropin-releasing hormone receptors in rat testis and their role in isolated Leydig cells. Cell Tissue Res., 334: 283-294.
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