Hi, I am Shougang Zhuang, My LiveDNA is 86.6331
 
   
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Dr. Shougang Zhuang
 
Highest Degree: Ph.D. in Medical Science from Yokohama City University, Japan
 
Institute: Tongji University School of Medicine, China
 
Area of Interest: Medicine
  •   Biomedical Engineering
  •   Cell Physiology
  •   Oncogene
  •   Biological Chemistry
 
URL: http://livedna.org/86.6331
 
My SELECTED Publications
1:   Bao, H., Z. Liu, Y. Ge, S.M. Yang and S. Zhuang et al., 2012. Protection against NSAID induced acute kidney injury by GSK3β inhibition: effects on mitochondrial permeability transition and ATP production. Kidney Int., 81: 662-673.
2:   Chen, H.P., M. DeNicola, X. Qin, Y. Zhao and L. Zhang et al., 2011. HDAC inhibition promotes cardiogenesis and the survival of embryonic stem cells through proteasome-dependent pathway. J. Cell. Biochem., 112: 3246-3255.
CrossRef  |  PubMed  |  Direct Link  |  
3:   Gao, B., J. Yang, S. Zhuang, Y. Deng and W. Yang et al., 2007. Mollaret meningitis associated with an intraspinal epidermoid cyst. Pediatrics, 120: e220-e224.
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4:   Ge, Y., J. Si, L. Tian, S. Zhuang, L.D. Dworkin and R. Gong, 2011. Conditional ablation of glycogen synthase kinase 3β in postnatal mouse kidney. Lab. Invest., 91: 85-96.
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5:   Guan, Y.J., Z. Zhang, C. Yu, L. Ma and W. Hu et al., 2011. Phospho-SXXE/D motif mediated TNF receptor 1-TRADD death domain complex formation for T cell activation and migration. J. Immunol., 187: 1289-1297.
CrossRef  |  PubMed  |  
6:   Hallman, M.A., S. Zhuang and R.G. Schnellmann, 2008. Regulation of dedifferentiation and redifferentiation in renal proximal tubular cells by the epidermal growth factor receptor. J. Pharmacol. Exp. Ther., 325: 520-528.
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7:   Hao, J., S. Zhuang and Z. Wang, 2000. Effect of calcium bicarbonate on callium and phosphate in patients on hemodialysis. Youji Med. J., 23: 16-18.
8:   He, S., N. Liu, G. Bayliss and S. Zhuang, 2013. EGFR activity is required for renal tubular cell dedifferentiation and proliferation in a murine model of folic acid-induced acute kidney injury. Am. J. Physiol. Renal Physiol., 304: F356-F366.
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9:   Jiang, W., H. Yan and S. Zhuang, 2012. Update on cardiorenal syndrome. Chin. J. Nephrol., 28: 151-154.
10:   Kochevar, I.E., M.C. Lynch, S. Zhuang and C.R. Lambert, 2000. Singlet oxygen, but not oxidizing radicals, induces apoptosis in HL-60 cells. Photochem. Photobiol., 72: 548-553.
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11:   Lan, Y.,H. Qi,S. Zhuang and H. Yan, 2012. Application of sodium citrate combined with modified dialysate in continuous venous-venous hemodialysis. Shanghai Med. J., 35: 112-115.
12:   Li, S., Y. Zhou, J. Fan, S. Cao and T. Cao et al., 2011. Heat shock protein 72 enhances autophagy as a protective mechanism in lipopolysaccharide-induced peritonitis in rats. Am. J. Pathol., 179: 2822-2834.
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13:   Li, X. and S. Zhuang, 2013. Acute kidney injury in HIV infection. J. Trop. Dis., 1: 101-101.
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14:   Li, X., J. Wang, H. Yan and S. Zhuang, 2011. α-lipoic acid attenuates TGF-β1 and CTGF overexpression in STZ-induced diabetic nephropathy. J. Tongji Univ. (Med. Sci.), 32: 92-95.
15:   Liu, N. and S. Zhuang, 2011. Tissue protective and anti-fibrotic actions of suramin: New uses of an old drug. Curr. Clin. Pharmacol., 6: 137-142.
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16:   Liu, N., E. Tolbert, M. Pang, M. Ponnusamy, H. Yan and S. Zhuang, 2011. Suramin inhibits renal fibrosis in chronic kidney disease. J. Am. Soc. Nephrol., 22: 1064-1075.
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17:   Liu, N., E. Tolbert, M. Ponnusamy, H. Yan and S. Zhuang, 2011. Delayed administration of suramin attenuates the progression of renal fibrosis in obstructive nephropathy. J. Pharmacol. Exp. Ther., 338: 758-766.
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18:   Liu, N., J.K. Guo, M. Pang, E. Tolbert and M. Ponnusamy et al., 2012. Genetic or pharmacologic blockade of EGFR inhibits renal fibrosis. J. Am. Soc. Nephrol., 23: 854-867.
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19:   Liu, N., L. Fang, H. Yang and S. Zhuang, 2013. The role and mechanism of histone deacetylases in regulating progression of kidney diseases. Chin. J. Nephrol., 29: 72-75.
20:   Liu, N., S. He, E. Tolbert, R. Gong, G. Bayliss and S. Zhuang, 2012. Suramin alleviates glomerular injury and inflammation in the remnant kidney. PLoS One, Vol. 7. 10.1371/journal.pone.0036194.
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21:   Liu, N., S. He, L. Ma, M. Ponnusamy and J. Tang et al., 2013. Blocking the class I histone deacetylase ameliorates renal fibrosis and inhibits renal fibroblast activation via modulating TGF-Β and EGFR signaling. PloS One, Vol. 8. 10.1371/journal.pone.0054001.
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22:   Ma, L. and S. Zhuang, 2011. The role of STAT 3 in tissue fibrosis. Curr. Chem. Biol., 5: 44-51.
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23:   Ma, L., J.S. Gao, Y.J. Guan, X. Shi and H. Zhang et al., 2010. Acetylation modulates prolactin receptor dimerization. Proc. Natl. Acad. Sci., 107: 19314-19319.
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24:   Ma, L., S. Zhuang and Z. Wang, 1991. Acquired cystic disease of the kidney in patients undergoing maintenance hemodialysis. Chin. J. Dial. Eng., 2: 19-22.
25:   Ma, S., H. Yan, S. Zhuang, Y. Lan, R. Zhang and Y. Wang, 2012. Establishment of method for primary culture and passage of rat peritoneal mesothelial cells. J. Tonji Univ. (Med. Sci.), 33: 392-395.
26:   Ma, S.C., N. Liu, Y. Lan, S.G. Zhuang and H.D. Yan, 2013. Effect of suramin on the epithelial-mesenchymal transition in peritoneal mesothelial cells induced by high concentration glucose. Chin. J. Nephrol., 29: 142-146.
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27:   Mao, H., Z. Li, Y. Zhou, Z. Li and S. Zhuang et al., 2008. HSP72 attenuates renal tubular cell apoptosis and interstitial fibrosis in obstructive nephropathy. Am. J. Physiol. Renal Physiol., 295: F202-F214.
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28:   Marumo, F. and S. Zhuang, 1995. Nephrotic syndrome. Drugs, 126: 33-36.
29:   Murugavel, P., M. Pang, P.K. Annamaraju, Z. Zhang, R. Gong, Y.E. Chin and S. Zhuang, 2009. Transglutaminase-1 protects renal epithelial cells from oxidant-induced apoptosis through activation of Stat3 and Akt signaling pathways. Am. J. Physiol. Renal Physiol., 297: F1361-F1370.
30:   Pang, M. and S. Zhuang, 2010. Histone deacetylase: A potential therapeutic target for fibrotic disorders. J. Pharmacol. Exp. Ther., 335: 266-272.
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31:   Pang, M., J. Kothapally, H. Mao, E. Tolbert, M. Ponnusamy, Y.E. Chin and S. Zhuang, 2009. Inhibition of histone deacetylase activity attenuates renal fibroblast activation and interstitial fibrosis in obstructive nephropathy. Am. J. Physiol. Renal Physiol., 297: F996-F1005.
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32:   Pang, M., L. Ma, N. Liu, M. Ponnusamy, T.C. Zhao, H. Yan and S. Zhuang, 2011. Histone deacetylase 1/2 mediates proliferation of renal interstitial fibroblasts and expression of cell cycle proteins. J. Cell. Biochem., 112: 2138-2148.
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33:   Pang, M., L. Ma, R. Gong, E. Tolbert and H. Mao et al., 2010. A novel STAT3 inhibitor, S3I-201, attenuates renal interstitial fibroblast activation and interstitial fibrosis in obstructive nephropathy. Kidney Int., 78: 257-268.
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34:   Ponnusamy, M., L. Ma and S. Zhuang, 2013. Necrotic renal epithelial cell inhibits renal interstitial fibroblast activation: Role of protein tyrosine phosphatase 1B. Am. J. Physiol. Renal Physiol., 304: F698-F709.
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35:   Ponnusamy, M., L. Ma, R. Gong, M. Pang, Y.E. Chin and S. Zhuang, 2011. P2x7 receptors mediate deleterious renal epithelial-fibroblast cross talk. Am. J. Physiol. Renal Physiol., 300: F62-F70.
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36:   Ponnusamy, M., N. Liu, R. Gong, H. Yan and S. Zhuang, 2011. ERK pathway mediates P2X7 expression and cell death in renal interstitial fibroblasts exposed to necrotic renal epithelial cells. Am. J. Physiol. Renal Physiol., 301: F650-F659.
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37:   Ponnusamy, M., N. Liu, R. Sellamuthu, T.C. Zhao, H. Mao and S. Zhuang, 2012. Autophagy protects against necrotic renal epithelial cell-induced death of renal interstitial fibroblasts. Am. J. Physiol. Renal Physiol., 303: F83-F891.
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38:   Si, J., Y. Ge, S. Zhuang and R. Gong, 2010. Inhibiting nonmuscle myosin II impedes inflammatory infiltration and ameliorates progressive renal disease. Lab. Inves., 90: 448-458.
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39:   Si, J., Y. Ge, S. Zhuang, L.J. Wang, S. Chen and R. Gong, 2013. Adrenocorticotropic hormone ameliorates acute kidney injury by steroidogenic-dependent and independent mechanisms. Kidney Int., 83: 635-646.
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40:   Tang, J., H. Yan and S. Zhuang, 2012. Inflammation and oxidative stress in obesity-related glomerulopathy. Int. J. Nephrol., Vol. 2012. 10.1155/2012/608397.
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41:   Tang, J., H. Yan and S. Zhuang, 2013. Histone deacetylses as trargets for treatment of various diseases. Clin. Sci. (Lond.), 124: 651-662.
42:   Tang, J., N. Liu and S. Zhuang, 2013. Role of epidermal growth factor receptor in acute and chronic kidney injury. Kidney Int., 83: 804-810.
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43:   Tang, J., N. Liu, E. Tolbert, M. Ponnusamy and L. Ma et al., 2013. Sustained activation of EGFR triggers renal fibrogenesis after acute kidney injury. Am. J. Pathol., 183: 160-172.
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44:   Tang, J., Y. Yan, T.C. Zhao, G. Bayliss, H. Yan and S. Zhuang, 2013. Class I histone deacetylase activity is required for proliferation of renal epithelial cells. Am. J. Physiol. Renal Physiol., 305: F244-F254.
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45:   Wang, J., S. Liu, X. Li, H. Qi, S. Zhuang and H. Yan, 2012. Effects of different dialyzers on oxidative stress for maintenance hemodialysis patients. Shanghai Med. J., 35: 134-137.
46:   Wang, Z., Q. Ma, J. Hao and S. Zhuang, 1992. Evaluation of adequate hemodialysis by means of urea kinetic modeling. Chin. J. Org. Trans., 13: 212-216.
47:   Wang, Z., S. Zhuang, X. Yuang, Q. Ma, Y. Gao and L. Bai, 1991. The dynamic change of plasma calcium fractions during hemodialysis. J. Chin. Urol., 12: 358-360.
48:   Xing, J., Z. Zhang, H. Mao, R.G. Schnellmann and S. Zhuang, 2008. Src regulates cell cycle protein expression and renal epithelial cell proliferation via PI3K/Akt signaling-dependent and -independent mechanisms. Am. J. Physiol. Renal Physiol., 295: F145-F152.
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49:   Zhang, L., X. Qin, Y. Zhao, L. Fast and S. Zhuang et al., 2012. Inhibition of histone deacetylases preserves myocardial performance and prevents cardiac remodeling through stimulation of endogenous angiomyogenesis. J. Pharmacol. Exp. Ther., 341: 285-293.
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50:   Zhang, R.Q., S. Zhuang and H. Yang, 2011. Recent advances in peritoneal dialysis. Chin. J. Blood Purif., 11: 218-222.
51:   Zhang, X.T. and S. Zhuang, 2012. Clinical application of nocturnal hemodialysis. Chin. J. Nephrol. Dial Trans., 21: 179-182.
52:   Zhang, Z., J. Xing, L. Ma, R. Gong, Y.E. Chin and S. Zhuang, 2009. Transglutaminase-1 regulates renal epithelial cell proliferation through activation of Stat-3. J. Biol. Chem., 284: 3345-3353.
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53:   Zhao, T.C., J. Du, S. Zhuang, P. Liu and L.X. Zhang, 2013. HDAC inhibition elicits myocardial protective effect through modulation of MKK3/Akt-1. PloS One, Vol. 8. 10.1371/journal.pone.0065474.
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54:   Zhou, Y., H. Mao, S. Li, S. Cao and Z. Li et al., 2010. HSP72 inhibits Smad3 Activation and nuclear translocation in renal epithelial-to-mesenchymal transition. J. Am. Soc. Nephrol., 21: 598-609.
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55:   Zhuang, S. and G. Simon, 2000. Peroxynitrite-induced apoptosis involves activation of multiple caspases in HL-60 cells. Am. J. Physiol. Cell Physiol., 279: C341-C351.
PubMed  |  Direct Link  |  
56:   Zhuang, S. and H. Yan, 2011. Bilingual Manual of Nephrology. Shanghai Xuelin Publishing House, Shanghai, China.
57:   Zhuang, S. and I.E. Kochevar, 2003. Singlet oxygen-induced activation of Akt/protein kinase B is independent of growth factor receptors. Photochem. Photobiol., 78: 361-371.
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58:   Zhuang, S. and I.E. Kochevar, 2003. Ultraviolet a radiation induces rapid apoptosis of human leukemia cells by fas ligand-independent activation of the fas death pathway. Photochem. Photobiol., 78: 61-67.
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59:   Zhuang, S. and R.G. Schnellmann, 2004. H2O2-induced transactivation of EGF receptor requires Src and mediates ERK1/2, but not Akt, activation in renal cells. Am. J. Physiol. Renal Physiol., 286: F858-F865.
PubMed  |  Direct Link  |  
60:   Zhuang, S. and R.G. Schnellmann, 2005. Suramin promotes proliferation and scattering of renal epithelial cells. J. Pharmacol. Exp. Ther., 314: 383-390.
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61:   Zhuang, S. and R.G. Schnellmann, 2006. A death-promoting role for extracellular signal-regulated kinase. J. Pharmacol. Exp. Ther., 319: 991-997.
PubMed  |  
62:   Zhuang, S. and Z. Wang, 1992. Alternation of serum vitamin A levels in patients undergoing chronic hemodialysis. Beij. Biomed. Eng., 11: 173-174.
63:   Zhuang, S. and Z. Wang, 1992. First-use syndrome (a case report and literature review). Beij. Biomed. Eng., 11: 97-98.
64:   Zhuang, S., 1991. Dialysis Related Hematologic Disorders. In: Handbook of Dialysis, Wang, Z. (Ed.) 1st Edn., Beijing Sciences and Technology Publishing House, Beijing, China.
65:   Zhuang, S., 1992. Peritoneal Dialysis, Hemoperfusion and Arteriovenous Fistula. In: Blood Purification, Wang, Z. (Ed.) 1st Edn., Beijing Sciences and Technology Publishing House, Beijing, China.
66:   Zhuang, S., 2010. Renal Failure-Related Sleep Apnea Syndrome. In: Blood Purification, Wang, Z. (Ed.) 3rd Edn., Beijing Sciences and Technology Publishing House, Beijing, China.
67:   Zhuang, S., 2013. Regulation of STAT signaling by acetylation. Cell. Signal., 25: 1924-1931.
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68:   Zhuang, S., B. Lu and M. Pang, 2009. Postconditioning does not improve renal function or attenuate tubular damage in ischemia/reperfusion-induced acute kidney injury in mice. Open Pathol. J., 4: 18-21.
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69:   Zhuang, S., B. Lu, R.A. Daubert, K.D. Chavin, L. Wang and R.G. Schnellmann, 2009. Suramin promotes recovery from renal ischemia/reperfusion injury in mice. Kidney Int., 75: 304-311.
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70:   Zhuang, S., G.D. Ouedraogo and I.E. Kochevar, 2003. Downregulation of epidermal growth factor receptor signaling by singlet oxygen through activation of caspase-3 and protein phosphatases. Oncogene, 22: 4413-4424.
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71:   Zhuang, S., G.R. Kinsey, K. Rasbach and R.G. Schnellmann, 2008. Heparin-binding epidermal growth factor and Src family kinases in proliferation of renal epithelial cells. Am. J. Physiol. Renal Physiol., 294: F459-F468.
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72:   Zhuang, S., J.T. Demirs and I.E. Kochevar, 2000. p38 mitogen-activated protein kinase mediates bid cleavage, mitochondrial dysfunction and caspase-3 activation during apoptosis induced by singlet oxygen but not by hydrogen peroxide. J. Biol. Chem., 275: 25939-25948.
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73:   Zhuang, S., J.T. Demirs and I.E. Kochevar, 2001. Protein kinase C inhibits singlet oxygen-induced apoptosis by decreasing caspase-8 activation. Oncogene, 20: 6764-6776.
PubMed  |  Direct Link  |  
74:   Zhuang, S., L. Hao and Z. Wang, 1992. Plasma concentration of ascorbic acid in patients undergoing maintenance hemodialysis. Beij. Biomed. Eng., 11: 44-45.
75:   Zhuang, S., L. Ma and Z. Wang, 1993. Cerebral hemorrage in patients on maintenance hemodialysis (with analysis of 8 cases). Beij. Biomed. Eng., 12: 39-40.
76:   Zhuang, S., M. Duan and Y. Yan, 2012. Src family kinases regulate renal epithelial dedifferentiation through activation of EGFR/PI3K signaling. J. Cell. Physiol., 227: 2138-2144.
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77:   Zhuang, S., M.C. Lynch and I.E. Kochevar, 1999. Caspase-8 mediates caspase-3 activation and cytochrome c release during singlet oxygen-induced apoptosis of HL-60 cells. Exp. Cell Res., 250: 203-212.
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78:   Zhuang, S., M.C. lynch and I.E. Kochevar, 1998. Activation of protein kinase C is required for protection of cells against apoptosis induced by singlet oxygen. FEBS Lett., 437: 158-162.
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79:   Zhuang, S., R.K. Gilbert, Y. Yan, J. Han and R.G. Schnellmann, 2008. ERK activation mediates mitochondria dysfunction and necrosis induced by hydrogen peroxide in renal proximal tubular cells. J. Pharmacol. Exp. Ther., 325: 732-740.
80:   Zhuang, S., S.I. Hirai and S. Ohno, 2000. Hyperosmolality induces activation of cPKC and nPKC, a requirement for ERK1/2 activation in NIH/3T3 cells. Am. J. Physiol. Cell Physiol., 278: C102-C109.
PubMed  |  Direct Link  |  
81:   Zhuang, S., S.I. Hirai, K. Mizuno, A. Suzuki and K. Akimoto et al., 1997. Involvement of protein kinase C during activation of mitogen-activated protein kinase by UV irradiation. Biochem. Biophys. Res. Commun., 240: 273-278.
82:   Zhuang, S., W. Li and Z. Wang, 1993. Effect of large doses of vitamin E on anemia in patients undergoing maintenance hemodialysis. Beij. Biomed. Eng., 12: 36-38.
83:   Zhuang, S., Y. Dang and R.G. Schnellmann, 2004. Requirement of the epidermal growth factor receptor in renal epithelial cell proliferation and migration. Am. J. Physiol. Renal Physiol., 287: F365-F372.
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84:   Zhuang, S., Y. Yan, J. Han and R.G. Schnellmann, 2005. p38 kinase-mediated transactivation of the epidermal growth factor receptor is required for dedifferentiation of renal epithelial cells after oxidant injury. J. Biol. Chem., 280: 21036-21042.
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85:   Zhuang, S., Y. Yan, R.A. Daubert and R.G. Schnellmann, 2007. Epiregulin promotes proliferation and migration of renal proximal tubular cells. Am. J. Physiol. Renal Physiol., 293: F219-F226.
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86:   Zhuang, S., Y. Yan, R.A. Daubert, J. Han and G.R. Schnellmann, 2007. ERK promotes hydrogen peroxide-induced apoptosis through caspase-3 activation and inhibition of Akt in renal epithelial cells. Am. J. Physiol. Renal Physiol., 292: F440-F447.
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87:   Zhuang, S., Z. Li and H. Yan, 1992. The change of plasma atrial natriuretic factor levels in chronic renal failure during hemodialysis. Beij. Biomed. Eng., 11: 93-96.
88:   Zhuang, S., Z. Wang, J. Hao, H. Zhao and X. Fang, 1993. Sources of endotoxemia in patients with hemodialysis. Beij. Biomed. Eng., 12: 117-119.