Dr. Zhi Long Chen
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Dr. Zhi Long Chen

Research Scientist
Donghua University, China

Highest Degree
Ph.D. in Medicinal Chemistry and Pharmacology from Second Military Medical University, China

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Area of Interest:

Chemistry
100%
Photosensitizers
62%
Photodynamic Therapy
90%
Drug Delivery Systems
75%
Medicinal Chemistry
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Nie, Y.Y., Y.J. Da, H. Zheng, X.X. Yang and L. Jia et al., 2012. Synthesis and biological evaluation of novel potent angiotensin II receptor antagonists with anti-hypertension effect. Bioorganic Medic. Chem., 20: 2747-2761.
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  2. Da, Y.J., W.D. Yuan, T. Xin, Y.Y. Nie and Y. Ye et al., 2012. Synthesis and biological evaluation of new fluorine substituted derivatives as angiotensin II receptor antagonists with anti-hypertension and anti-tumor effects. Bioorganic Medic. Chem., 20: 7101-7111.
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  3. Yan, Y.J., M.Z. Zheng, Z.L. Chen, X.H. Yu, X.X. Yang, Z.L. Ding and L. Xu, 2010. Studies on preparation and photodynamic mechanism of chlorin P6-13, 15-N-(cyclohexyl)cycloimide (Chlorin-H) and its anti-tumor effect for photodynamic therapy in vitro and in vivo. Bioorganic Medic. Chem., 18: 6282-6291.
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  4. Sun, Y., Z.L. Chen, X.X. Yang, P. Huang, X.P. Zhou and X.X. Du, 2009. Magnetic chitosan nanoparticles as a drug delivery system for targeting photodynamic therapy. Nanotechnology, Vol. 20. 10.1088/0957-4484/20/13/135102.
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  5. Lu, S., J. Yang, Z.L. Chen, S. Gong, H. Zhou, X. Xu and J. Wang, 2009. Different mutants of PSMB5 confer varying bortezomib resistance in T lymphoblastic lymphoma/leukemia cells derived from the Jurkat cell line. Exp. Hematol., 37: 831-837.
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  6. Liu, F.X., X.P. Zhou, S. Ni, X. Wang, Y. Zhou and Z.L. Chen, 2009. Preparation and properties of photosensitizer loaded magnetic nanocomposites. Curr. Nanosci., 5: 293-296.
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  7. Chen, Z.L., Y. Sun, P. Huang, X.X. Yang and X.P. Zhou, 2009. Studies on preparation of photosensitizer loaded magnetic silica nanoparticles and their antitumor effects for targeting photodynamic therapy. Nanoscale Res. Lett., 4: 400-408.
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  8. Zhou, X.P., X.Q. Wang, F.X. Liu, Z.L. Chen and A. Kasuya, 2008. Luminescence stability of the silica encapsulated CdSe nanoparticles. Curr. Nanosci., 4: 88-91.
  9. Lu, S.Q., Z.L. Chen, J.M. Yang, L. Chen and S.L. Gong et al., 2008. Overexpression of the PSMB5 gene contributes to bortezomib resistance in T-lymphoblastic lymphoma/leukemia cells derived from Jurkat line. Exp. Hematol., 36: 1278-1284.
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  10. Liu, F.X., X.P. Zhou, Z.L. Chen, P. Huang, X.Q. Wang and Y. Zhou, 2008. Preparation of purpurin-18 loaded magnetic nanocarriers in cottonseed oil for photodynamic therapy. Mater. Lett., 62: 2844-2847.
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