Mr. Xuefeng Wang
My Social Links

Mr. Xuefeng Wang

Laboratory Director/Head
Chongqing Medical University, China

Highest Degree
Masters in Medicine from Chongqing Medical University, China

Share this Profile

Area of Interest:

Medicine
100%
Experimental Neurology
62%
Neurochemical Research
90%
Cancer Research
75%
Seizures
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Zhu, Q., L. Wang, Z. Xiao, F. Xiao and J. Luo et al., 2013. Decreased expression of Ras-GRF1 in the brain tissue of the intractable epilepsy patients and experimental rats. Brain Res., 1493: 99-109.
    CrossRef  |  Direct Link  |  
  2. Zhang, X., G. Chen, Y. Lu, J. Liu and M. Fang et al., 2013. Association of mitochondrial Letm1 with epileptic seizures. Cerebral Cortex. (In Press). 10.1093/cercor/bht118.
    CrossRef  |  Direct Link  |  
  3. Xiao, F., J. Li, X. Zhang and X. Wang, 2013. Antiepileptic treatment and blood lactate level alteration in patients with Myoclonic Epilepsy with Ragged-red Fibers (MERRF) syndrome in a Chinese family. Neurol. Asia, 18: 47-51.
    Direct Link  |  
  4. Jiang, G., Q. Cao, J. Li, Y. Zhang and X. Liu et al., 2013. Altered expression of vesicular monoamine transporter 2 in epileptic patients and experimental rats. Synapse, 67: 415-426.
    CrossRef  |  Direct Link  |  
  5. Du, Y., Y. Zou, W. Yu, R. Shi and M. Zhang et al., 2013. Expression pattern of sorting nexin 25 in temporal lobe epilepsy: A study on patients and pilocarpine-induced rats. Brain Res., 1509: 79-85.
    CrossRef  |  Direct Link  |  
  6. Chen, Y. and X. Wang, 2013. Association between seizures and diabetes mellitus: A comprehensive review of literature. Curr. Diabetes Rev., 9: 350-354.
    CrossRef  |  PubMed  |  
  7. Zhu, Q., L. Wang, Y. Zhang, F.H. Zhao and J. Luo et al., 2012. Increased expression of DNA methyltransferase 1 and 3a in human temporal lobe epilepsy. J. Mol. Neurosci., 46: 420-426.
    CrossRef  |  Direct Link  |  
  8. Zhao, F., Y. Hu, Y. Zhang, Q. Zhu and X. Zhang et al., 2012. Abnormal expression of stathmin 1 in brain tissue of patients with intractable temporal lobe epilepsy and a rat model. Synapse, 66: 781-791.
    CrossRef  |  Direct Link  |  
  9. Zhang, Y., Y. Xu, Q. Zhu, F. Zhao, J. Luo, X. Zhang and X. Wang, 2012. Upregulation of dysbindin in temporal lobe epileptic foci of human and experimental animals. Synapse, 66: 622-629.
    CrossRef  |  Direct Link  |  
  10. Zhang, C.Q., X.F. Wang, Z.C. Huang and L.S. Xu, 2012. Analysis of ictal semiology: Contralateral tonic activity associated with ipsilateral automotor seizure in temporal lobe epilepsy. Neurol. Asia, 17: 109-113.
    Direct Link  |  
  11. Xu, Y., Y. Zhang, Z. Guo, H. Yin and K. Zeng et al., 2012. Increased placental growth factor in cerebrospinal fluid of patients with epilepsy. Neurochem. Res., 37: 665-670.
    CrossRef  |  Direct Link  |  
  12. Xu, Y., K. Zeng, Y. Han, L. Wang and D. Chen et al., 2012. Altered expression of CX3CL1 in patients with epilepsy and in a rat model. Am. J. Pathol., 180: 1950-1962.
    CrossRef  |  Direct Link  |  
  13. Xu, Y., J. Luo, Z. Yue, L. Wu and X. Zhang et al., 2012. Increased expression of placental growth factor in patients with temporal lobe epilepsy and a rat model. Brain Res., 1429: 124-133.
    CrossRef  |  Direct Link  |  
  14. Wu, M., M. Fang, Y. Hu and X. Wang, 2012. Four types of traditional Chinese medicine inducing epileptic seizures. Seizure, 21: 311-315.
    CrossRef  |  Direct Link  |  
  15. Wang, W., L. Wang, J. Luo, Z. Xi, X. Wang, G. Chen and L. Chu, 2012. Role of a neural cell adhesion molecule found in cerebrospinal fluid as a potential biomarker for epilepsy. Neurochem. Res., 37: 819-825.
    CrossRef  |  Direct Link  |  
  16. Wang, L., J. Luo, M. Fang, G. Jiang, X. Zhang, W. Yu and X. Wang, 2012. A new trick of INPP4A: Decreased expression of INPP4A in patients with temporal lobe epilepsy and pilocarpine-induced rat model. Synapse, 66: 533-541.
    CrossRef  |  Direct Link  |  
  17. Tao, S., X. Yang, Y. Chen, X. Wang and Z. Xiao et al., 2012. Up-regulated methyl CpG binding protein-2 in intractable temporal lobe epilepsy patients and a rat model. Neurochem. Res., 37: 1886-1897.
    CrossRef  |  Direct Link  |  
  18. Peng, X., L. Wang, G. Chen and X. Wang, 2012. Dynamic expression of adenylate kinase 2 in the hippocampus of pilocarpine model rats. J. Mol. Neurosci., 47: 150-157.
    CrossRef  |  Direct Link  |  
  19. Luo, J., K. Zeng, C. Zhang, M. Fang and X. Zhang et al., 2012. Down-regulation of CRMP-1 in patients with epilepsy and a rat model. Neurochem. Res., 37: 1381-1391.
    CrossRef  |  Direct Link  |  
  20. Liu, X.Y. and X.F. Wang, 2012. Brain-tumor related epilepsy: Review of the literature. Cancer Therapy, 8: 130-138.
    Direct Link  |  
  21. Huang, Y., F. Zhao, L. Wang, H. Yin, C. Zhou and X. Wang, 2012. Increased expression of histone deacetylases 2 in temporal lobe epilepsy: A study of epileptic patients and rat models. Synapse, 66: 151-159.
    CrossRef  |  Direct Link  |  
  22. Hu, Y., X. Huang, D. Shen, M. Ding and H. Sun et al., 2012. Outcomes of sustained-release formulation of valproate and topiramate monotherapy in patients with epilepsy: A multi-centre, cohort study. PLoS ONE, Vol. 7. 10.1371/journal.pone.0047982.
    CrossRef  |  Direct Link  |  
  23. Han, Y., H. Yin, Y. Xu, Q. Zhu, J. Luo, X. Wang and G. Chen, 2012. Increased expression of calponin-3 in epileptic patients and experimental rats. Exp. Neurol., 233: 430-437.
    CrossRef  |  Direct Link  |  
  24. Chen, D., Y. Lu, W. Yu, J. Luo, Z. Xiao, F. Xiao and X. Wang, 2012. Clinical value of decreased superoxide dismutase 1 in patients with epilepsy. Seizure, 21: 508-511.
    CrossRef  |  Direct Link  |  
  25. Zhou, S.N., C.S. Li, L.Q. Liu, Y. Li, X.F. Wang and L. Shen, 2011. Increased expression of annexin A7 in temporal lobe tissue of patients with refractory epilepsy. Histol. Histopathol., 26: 571-579.
    PubMed  |  Direct Link  |  
  26. Zhang, X., X. Peng, M. Fang, C. Zhou and F. Zhao et al., 2011. Up-regulation of apelin in brain tissue of patients with epilepsy and an epileptic rat model. Peptides, 32: 1793-1799.
    CrossRef  |  Direct Link  |  
  27. Yin, H., L. Wang, F. Xiao, Z. Huang and Y. Huang et al., 2011. Upregulation of liprin-α1 protein in the temporal neocortex of intractable epileptic patients and experimental rats. Synapse, 65: 742-750.
    CrossRef  |  Direct Link  |  
  28. Xu, Z., T. Xue, Z. Zhang, X. Wang and P. Xu et al., 2011. Role of signal transducer and activator of transcription-3 in up-regulation of GFAP after epilepsy. Neurochem. Res., 36: 2208-2215.
    CrossRef  |  Direct Link  |  
  29. Xi, Z.Q., X.F. Wang, X.F. Shu, G.J. Chen, F. Xiao, J.J. Sun and X. Zhu, 2011. Is intractable epilepsy a tauopathy? Med. Hypotheses, 76: 897-900.
    CrossRef  |  Direct Link  |  
  30. Wu, Y., X.F. Wang, X.A. Mo, J.M. Li and J. Yuan et al., 2011. Expression of laminin β1 and integrin α2 in the anterior temporal neocortex tissue of patients with intractable epilepsy. Int. J. Neurosci., 121: 323-328.
    CrossRef  |  Direct Link  |  
  31. Shen, L., Z. Xiao, Y. Pan, M. Fang and C. Li et al., 2011. Altered expression of Dscam in temporal lobe tissue from human and experimental animals. Synapse, 65: 975-982.
    CrossRef  |  Direct Link  |  
  32. Peng, X., X. Zhang, L. Wang, Q. Zhu and J. Luo et al., 2011. Gelsolin in cerebrospinal fluid as a potential biomarker of epilepsy. Neurochem. Res., 36: 2250-2258.
    CrossRef  |  Direct Link  |  
  33. Luo, J., Y. Xu, Q. Zhu, F. Zhao and Y. Zhang et al., 2011. Expression pattern of Mical-1 in the temporal neocortex of patients with intractable temporal epilepsy and Pilocarpine-induced rat model. Synapse, 65: 1213-1221.
    CrossRef  |  Direct Link  |  
  34. Lu, Y., Z. Xiao, W. Yu, F. Xiao and Z. Xiao et al., 2011. Efficacy and safety of adjunctive zonisamide in adult patients with refractory partial-onset epilepsy: A randomized, double-blind, placebo-controlled trial. Clin. Drug Investig., 31: 221-229.
    CrossRef  |  PubMed  |  Direct Link  |  
  35. Hu, Y., Y. Huang, F. Quan, Y. Hu, Y. Lu and X.F. Wang, 2011. Comparison of the retention rates between carbamazepine and valproate as an initial monotherapy in Chinese patients with partial seizures: A ten-year follow-up, observational study. Seizure, 20: 208-213.
    CrossRef  |  Direct Link  |  
  36. Fang, M., Z.Q. Xi, Y. Wu and X.F. Wang, 2011. A new hypothesis of drug refractory epilepsy: Neural network hypothesis. Med. Hypotheses, 76: 871-876.
    CrossRef  |  Direct Link  |  
  37. Fang, M., Y. Lu, G.J. Chen, L. Shen, Y.M. Pan and X.F. Wang, 2011. Increased expression of Sonic hedgehog in temporal lobe epileptic foci in humans and experimental rats. Neuroscience, 182: 62-70.
    CrossRef  |  Direct Link  |  
  38. Fang, M., L. Shen, H. Yin, Y.M. Pan and L. Wang et al., 2011. Downregulation of gephyrin in temporal lobe epilepsy neurons in humans and a rat model. Synapse, 65: 1006-1014.
    CrossRef  |  Direct Link  |  
  39. Zeng, K., X. Wang, Z. Xi and Y. Yan, 2010. Adverse effects of carbamazepine, phenytoin, valproate and lamotrigine monotherapy in epileptic adult Chinese patients. Clin. Neurol. Neurosurgery, 112: 291-295.
    CrossRef  |  
  40. Yuan, J., L.Y. Wang, J.M. Li, N.J. Cao and L. Wang et al., 2010. Altered expression of the small guanosine triphosphatase RhoA in human temporal lobe epilepsy. J. Mol. Neurosci., 42: 53-58.
    CrossRef  |  Direct Link  |  
  41. Xiao, Z., L. Shen, D. Chen, L. Wang, Z. Xi, F. Xiao and X. Wang, 2010. Talin 2 concentrations in cerebrospinal fluid in patients with epilepsy. Clin. Biochem., 43: 1129-1132.
    CrossRef  |  
  42. Wang, L., Y. Pan, D. Chen, Z. Xiao, Z. Xi, F. Xiao and X. Wang, 2010. Tetranectin is a potential biomarker in cerebrospinal fluid and serum of patients with epilepsy. Clinica Chimica Acta, 411: 581-583.
    CrossRef  |  
  43. Wang, L., Y. Han, D. Chen, Z. Xiao, Z. Xi, F. Xiao and X. Wang, 2010. Cerebrospinal fluid apolipoprotein E concentration decreases after seizure. Seizure, 19: 79-83.
    CrossRef  |  Direct Link  |  
  44. Wang, L., G. Liu, M. He, L. Shen, D. Shen, Y. Lu and X. Wang, 2010. Increased insulin receptor expression in anterior temporal neocortex of patients with intractable epilepsy. J. Neurol. Sci., 296: 64-68.
    CrossRef  |  Direct Link  |  
  45. Wang, L., C. Zhou, Q. Zhu, J. Luo and Y. Xu et al., 2010. Up-regulation of serum- and glucocorticoid-induced protein kinase 1 in the brain tissue of human and experimental epilepsy. Neurochem. Int., 57: 899-905.
    CrossRef  |  Direct Link  |  
  46. Pan, Y., G. Liu, M. Fang, L. Shen and L. Wang et al., 2010. Abnormal expression of netrin-G2 in temporal lobe epilepsy neurons in humans and a rat model. Exp. Neurol., 224: 340-346.
    CrossRef  |  Direct Link  |  
  47. Lu, Y., W. Yu, Z. Xi, Z. Xiao, X. Kou and X.F. Wang, 2010. Mutational analysis of SCN2B, SCN3B and SCN4B in a large Chinese Han family with generalized tonic-clonic seizure. Neurol. Sci., 31: 675-677.
    CrossRef  |  Direct Link  |  
  48. Hu, Y., Y. Lu, W. Yu, D. Shen, Z. Xiao, Z. Xi and X. Wang, 2010. Long-term retention rate of topiramate as initial monotherapy in Chinese patients with newly diagnosed epilepsy: A prospective, observational study. Epilepsy Res., 90: 278-284.
    CrossRef  |  Direct Link  |  
  49. Fang, M., G.W. Liu, Y.M. Pan, L. Shen and C.S. Li et al., 2010. Abnormal expression and spatiotemporal change of Slit2 in neurons and astrocytes in temporal lobe epileptic foci: A study of epileptic patients and experimental animals. Brain Res., 1324: 14-23.
    CrossRef  |  Direct Link  |  
  50. Zeng, K., X.F. Wang, Y. Wang and Y. Yan, 2009. Enhanced synaptic vesicle traffic in hippocampus of phenytoin-resistant kindled rats. Neurochem. Res., 34: 899-904.
    CrossRef  |  Direct Link  |  
  51. Xiao, Z., Y. Gong, X.F. Wang, F. Xiao, Z.Q. Xi, Y. Lv and H.B. Sun, 2009. Efficacy and safety of levetiracetam (3,000 mg/Day) as an adjunctive therapy in Chinese patients with refractory partial seizures. Eur. Neurol., 61: 233-239.
    CrossRef  |  Direct Link  |  
  52. Xiao, Z., Y. Gong, X.F. Wang, F. Xiao, Z.Q. Xi, Y. Lu and H.B. Sun, 2009. Altered expression of synaptotagmin I in temporal lobe tissue of patients with refractory epilepsy. J. Mol. Neurosci., 38: 193-200.
    CrossRef  |  Direct Link  |  
  53. Xiao, F., D. Chen, Y. Lu, Z. Xiao and L.F. Guan et al., 2009. Proteomic analysis of cerebrospinal fluid from patients with idiopathic temporal lobe epilepsy. Brain Res., 1255: 180-189.
    CrossRef  |  Direct Link  |  
  54. Xi, Z.Q., F. Xiao, J. Yuan, X.F. Wang, L. Wang, F.Y. Quan and G.W. Liu, 2009. Gene expression analysis on anterior temporal neocortex of patients with intractable epilepsy. Synapse, 63: 1017-1028.
    CrossRef  |  Direct Link  |  
  55. Wu, Y., Y. Feng, J.R. Pang, M. Tang, X.Y. Liu, J.Q. Li and X.F. Wang, 2009. Study on expression of laminin in patients with intractable epilepsy. Int. J. Neurosci., 119: 2219-2227.
    CrossRef  |  Direct Link  |  
  56. Wu, X.Y., Z. Hong, X. Wu, L.W. Wu and X.F. Wang et al., 2009. Multicenter double-blind, randomized, placebo-controlled trial of levetiracetam as add-on therapy in Chinese patients with refractory partial-onset seizures. Epilepsia, 50: 398-405.
    CrossRef  |  Direct Link  |  
  57. Wang, L., X. Wang, J. Yuan, Z. Xi, T. Xue, Y. Li and Z. Xiao, 2009. Nestin in the temporal neocortex of the intractable epilepsy patients. Neurochem. Res., 34: 574-580.
    CrossRef  |  Direct Link  |  
  58. Lu, Y., W. Yu and X.F. Wang, 2009. Efficacy of topiramate in adult patients with symptomatic epilepsy. CNS Drugs, 23: 351-359.
    CrossRef  |  Direct Link  |  
  59. Lu, Y., T. Xue, J. Yuan, Y. Li and Y. Wu et al., 2009. Increased expression of TGFβ type I receptor in brain tissues of patients with temporal lobe epilepsy. Clin. Sci., 117: 17-22.
    CrossRef  |  Direct Link  |  
  60. Lu, Y. and X. Wang, 2009. Genes associated with idiopathic epilepsies: A current overview. Neurol. Res., 31: 135-143.
    CrossRef  |  PubMed  |  
  61. Li, Y.Q., T. Xue, L. Wang, Z.C. Xu and Z.Q. Xi et al., 2009. Up-regulation of epithelial membrane protein-1 in the temporal neocortex of patients with intractable epilepsy. Neurochem. Res., 34: 1594-1602.
    CrossRef  |  Direct Link  |  
  62. Zhou, S., X. Sun, X. Wang and K. Liu, 2008. Increased expression of aquaporin-1 in the anterior temporal neocortex of patients with intractable epilepsy. Neurol. Res., 30: 400-405.
    CrossRef  |  PubMed  |  
  63. Xiao, F., X.F. Wang, J.M. Li, Z.Q. Xi and Y. Lu et al., 2008. Overexpression of N-WASP in the brain of human epilepsy. Brain Res., 1233: 168-175.
    CrossRef  |  Direct Link  |  
  64. Wu, Y., X.F. Wang, X.A. Mo, H.B. Sun and J.M. Li et al., 2008. Expression of laminin β1 in hippocampi of patients with intractable epilepsy. Neurosci. Lett., 443: 160-164.
    CrossRef  |  PubMed  |  Direct Link  |  
  65. Wu, Y., X.F. Wang, X. Mo, Z. Xi and F. Xiao et al., 2008. Expression of monocyte chemoattractant protein-1 in brain tissue of patients with intractable epilepsy. Clin. Neuropathol., 27: 55-63.
    PubMed  |  Direct Link  |  
  66. Wang, X.F. and Y. Lu, 2008. Genetic etiology of new forms of familial epilepsy. Front. Biosci., 13: 3159-3167.
    PubMed  |  
  67. Lu, Y., Y. Yu, D. Shen and X.F. Wang, 2008. Three new forms of familial epilepsy syndromes in the proposed diagnostic scheme of the ILAE (2001): A clinical experience in Southwest China. Epilpsia, 49: 1103-1103.
    CrossRef  |  Direct Link  |  
  68. Lu, Y., X.F. Wang, Y. Yan, Z. Xiao and U. Stephani, 2008. Nongenetic cause of epileptic seizures in 2 otherwise healthy Chinese families: Tetramine-case presentation and literature survey. Clin. Neuropharmacol., 31: 57-61.
    CrossRef  |  PubMed  |  
  69. Xi, Z.Q., X.F. Wang, R.Q. He, M.W. Li and X.Z. Liu et al., 2007. Extracellular signal-regulated protein kinase in human intractable epilepsy. Eur. J. Neurol., 14: 865-872.
    CrossRef  |  Direct Link  |  
  70. Xi, Z.Q., X.F. Wang, J.J. Sun, X.Z. Liu and X. Zhu et al., 2007. TDAG51 in the anterior temporal neocortex of patients with intractable epilepsy. Neurosci. Lett., 425: 53-58.
    CrossRef  |  Direct Link  |  
  71. Xi, Z.Q., J.J. Sun, X.F. Wang, M.W. Li and X.Z. Liu et al., 2007. HSPBAP1 is found extensively in the anterior temporal neocortex of patients with intractable epilepsy. Synapse, 61: 741-747.
    CrossRef  |  Direct Link  |  
  72. Lu, Y., X. Wang, Q. Li, J. Li and Y. Yan, 2007. Tolerability and safety of topiramate in chinese patients with epilepsy. Clin. Drug Invest., 27: 683-690.
    CrossRef  |  Direct Link  |  
  73. Liu, F.Y., X.F. Wang, M.W. Li, J.M. Li and Z.Q. Xi et al., 2007. Upregulated expression of postsynaptic density-93 and N-methyl-D-aspartate receptors subunits 2B mRNA in temporal lobe tissue of epilepsy. Biochem. Biophys. Res. Commun., 358: 825-830.
    CrossRef  |  Direct Link  |  
  74. Li, J.M., X.F. Wang, Z.Q. Xi, Y. Gong and F.Y. Liu et al., 2006. Decreased expression of thyroid receptor-associated protein 220 in temporal lobe tissue of patients with refractory epilepsy. Biochem. Biophys. Res. Commun., 348: 1389-1397.
    CrossRef  |  Direct Link  |  
  75. Lu, Y., Y. Yan and X.F. Wang, 2004. Antiepileptic drug-induced multidrug resistance P-glycoprotein overexpression in astrocytes cultured from rat brains. Chin. Med. J., 117: 1682-1686.
    PubMed  |  Direct Link  |  
  76. Yang, M.S., X.F. Wang, W. Qin, G.Y. Feng and L. He, 2003. Evidence for a major susceptibility locus at 11q22.1-23.3 has been detected in a large Chinese family with pure grand mal epilepsy. Neurosci. Lett., 346: 133-136.
    CrossRef  |  Direct Link  |