Dr. Hong-Xi  Xu

Dr. Hong-Xi Xu

Professor
Shanghai University of Traditional Chinese Medicine, China


Highest Degree
Ph.D. in Pharmaceutical Sciences from Toyama Medical and Pharmaceutical University, Toyama, Japan

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Area of Interest:

Pharmacology and Toxicology
100%
Gastroenterology
62%
Ethnopharmacology
90%
Cancer
75%
Biomedical Chromatography
55%

Selected Publications

  1. Zhang, X. L., L.F. Liu, L.Y. Zhu, Y.J. Bai and Q. Mao et al., 2014. A high performance liquid chromatography fingerprinting and ultra high performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry chemical profiling approach to rapidly find characteristic chemical markers for quality evaluation of dispensing granules, a case study on Chuanxiong Rhizoma. J. Pharm. Biomed. Anal., 88: 391-400.
    CrossRef  |  

  2. Zhou, Y., B. Xia, M.H. Qiu, L.S. Ding and H.X. Xu, 2013. Fast analysis of triterpenoids in Ganoderma lucidum spores by ultra-performance liquid chromatography coupled with triple quadrupole mass spectrometry. Biomed. Chromatogr., 27: 1560-1567.
    CrossRef  |  

  3. Zhou, W.J., J.Z. Song, W.W. Fu, H.S. Tan, Z.X. Bian and H.X. Xu, 2013. Chemical comparison of two dosage forms of hemp seed pills by UHPLC-Q-ToF-MS/MS and multivariate statistical techniques. J. Pharm. Biomed. Anal., 84: 59-68.
    CrossRef  |  

  4. Xu, H.X., S. Mughal, O. Taiwo and S.F. Lee, 2013. Isolation and characterization of an antibacterial biflavonoid from an African chewing stick Garcinia kola Heckel (Clusiaceae). J. Ethnopharmacol., 147: 497-502.
    CrossRef  |  

  5. Li, J.R., M. Li, B. Xia, L.S. Ding, H.X. Xu and Y. Zhou, 2013. Efficient optimization of ultra-high- performance supercritical fluid chromatographic separation of Rosa sericea by response surface methodology. J. Sep. Sci., 36: 2114-2120.
    CrossRef  |  

  6. Li, J.R., J. Liu, D.H. He, H.X. Xu and L.S. Ding et al., 2013. Three new phenolic compounds from the leaves of Rosa sericea. Fitoterapia, 84: 332-337.
    CrossRef  |  

  7. Kan, W.L., C. Yin, H.X. Xu, G. Xu and K.K. To et al., 2013. Antitumor effects of novel compound, guttiferone K, on colon cancer by p21Waf1/Cip1-mediated G(0) /G(1) cell cycle arrest and apoptosis. Int. J. Cancer, 132: 707-716.
    CrossRef  |  

  8. Han, Q.B., W.L. Tang, C.X. Dong, H.X. Xu and Z.H. Jiang, 2013. An interesting two-phase solvent system and its use in preparative isolation of aconitines from aconite roots by counter-current chromatography. J. Sep. Sci., 36: 1304-1310.
    CrossRef  |  

  9. Xiao, H.T., S.W. Tsang, H.Y. Qin, F.F.K. Choi and Z.J. Yang et al., 2013. A bioactivity-guided study on the anti-diarrheal activity of Polygonum chinense Linn. J. Ethnopharmacol., 149: 499-505.
    CrossRef  |  

  10. Zhao, H.L., Y. Sui, C.F. Qiao, K.Y. Yip and R.K.K. Leung et al., 2012. Sustained antidiabetic effects of a berberine-containing Chinese herbal medicine through regulation of hepatic gene expression. Diabetes, 61: 933-943.
    CrossRef  |  

  11. Zhang, X.J., F.P. Leung, W.W. Hsiao, S. Tan and S. Li et al., 2012. Proteome profiling of spinal cord and dorsal root ganglia in rats with trinitrobenzene sulfonic acid-induced colitis. World J. Gastroenterol., 18: 2914-2928.
    Direct Link  |  

  12. Zhang, X.J., F.F.K. Choi, Y. Zhou, F.P. Leung and S. Tan et al., 2012. Metabolite profiling of plasma and urine from rats with TNBS-induced acute colitis using UPLC-ESI-QTOF-MS-based metabonomics: A pilot study. FEBS J., 279: 2322-2338.
    Direct Link  |  

  13. Zhang, H.M., S.L. Li, H. Zhang, Y. Wang, Z.L. Zhao, S.L. Chen and H.X. Xu, 2012. Holistic quality evaluation of commercial white and red ginseng using a UPLC-QTOF-MS/MS-based metabolomics approach. J. Pharm. Biomed. Anal., 62: 258-273.
    CrossRef  |  

  14. Yang, X.W., X. Deng, X. Liu, C.Y. Wu and X.N. Li et al., 2012. Hypercohin A, a new polycyclic polyprenylated acylphloroglucinol possessing an unusual bicyclo[5.3.1]hendecane core from Hypericum cohaerens. Chem. Commun., 48: 5998-6000.
    CrossRef  |  

  15. Xu, J., L.Y. Zhu, H. Shen, H.M. Zhang and X.B. Jia et al., 2012. A critical view on spike recovery for accuracy evaluation of analytical method for medicinal herbs. J. Pharm. Biomed. Anal., 62: 210-215.
    CrossRef  |  

  16. Xia, Z.X., D.D. Zhang, S. Liang, Y.Z. Lao and H. Zhang et al., 2012. Bioassay-guided isolation of prenylated xanthones and polycyclic acylphloroglucinols from the leaves of Garcinia nujiangensis. J. Nat. Prod., 75: 1459-1464.
    CrossRef  |  

  17. Wang, X., Y.J. Lou, M.X. Wang, Y.W. Shi, H.X. Xu and L.D. Kong, 2012. Furocoumarins affect hepatic cytochrome P450 and renal organic ion transporters in mice. Toxicol. Lett., 209: 67-77.
    CrossRef  |  

  18. Song, L., H. Zhang, X. Liu, Z.L. Zhao, S.L. Chen, Z.T. Wang and H.X. Xu, 2012. Rapid determination of yunaconitine and related alkaloids in aconites and aconite-containing drugs by ultra high-performance liquid chromatography-tandem mass spectrometry. Biomed. Chromatogr., 26: 1567-1574.
    Direct Link  |  

  19. Qin, H.Y., H.T. Xiao, F.P. Leung, Z.J. Yang and J.C.Y. Wu et al., 2012. JCM-16021, a Chinese herbal formula, attenuated visceral hyperalgesia in TNBS-induced postinflammatory irritable bowel syndrome through reducing colonic EC cell hyperplasia and serotonin availability in rats. Evidence-Based Complementary Alter. Med.,. 10.1155/2012/239638.
    CrossRef  |  

  20. Li, S.L., H. Shen, L.Y. Zhu, J. Xu and X.B. Jia et al., 2012. Ultra-high-performance liquid chromatography-quadrupole/time of flight mass spectrometry based chemical profiling approach to rapidly reveal chemical transformation of sulfur-fumigated medicinal herbs, a case study on white ginseng. J. Chromatogr. A, 1231: 31-45.
    CrossRef  |  

  21. He, D.H., L.S. Ding, H.X. Xu, X.X. Lei, H.P. Xiao and Y. Zhou, 2012. Gymnothelignans A-O: Conformation and absolute configuration analyses of lignans bearing tetrahydrofuran from gymnotheca chinensis. J. Org. Chem., 77: 8435-8443.
    CrossRef  |  

  22. Gao, X.M., T. Yu, M.Z. Cui, J.X. Pu and X. Du et al., 2012. Identification and evaluation of apoptotic compounds from Garcinia oligantha. Bioorg. Med. Chem. Lett., 22: 2350-2353.
    CrossRef  |  

  23. Fu, W.M., J.F. Zhang, H. Wang, Z.C. Xi and W.M. Wang et al., 2012. Heat shock protein 27 mediates the effect of 1,3,5-trihydroxy-13,13-dimethyl-2H-pyran [7,6-b] xanthone on mitochondrial apoptosis in hepatocellular carcinoma. J. Proteomics, 75: 4833-4843.
    CrossRef  |  

  24. Fu, W.M., J.F. Zhang, H. Wang, H.S. Tan and W.M. Wang et al., 2012. Apoptosis induced by 1,3,6,7-tetrahydroxyxanthone in Hepatocellular carcinoma and proteomic analysis. Apoptosis, 17: 842-851.
    CrossRef  |  

  25. Feng, C., L.Y. Zhou, T. Yu, G. Xu and H.L. Tian et al., 2012. A new anticancer compound, Oblongifolin C, inhibits tumor growth and promotes apoptosis in HeLa cells through bax activation. Int. J. Cancer, 131: 1445-1454.
    CrossRef  |  

  26. Zhou, Y., S.X. Huang, J.X. Pu, J.R. Li and L.S. Ding et al., 2011. Ultra performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometric procedure for qualitative and quantitative analyses of nortriterpenoids and lignans in the genus Schisandra. J. Pharm. Biomed. Anal., 56: 916-927.
    CrossRef  |  

  27. Zhou, Y., M.F. He, F.F. Choi, Z.H. He and J.Z. Song et al., 2011. A high-sensitivity UPLC-MS/MS method for simultaneous determination and confirmation of triptolide in zebrafish embryos. Biomed. Chromatogr., 25: 851-857.
    CrossRef  |  

  28. Qin, H.Y., J.C.Y. Wu, X.D. Tong, J.J.Y. Sung, H.X. Xu and Z.X. Bian, 2011. Systematic review of animal models of post-infectious/post-inflammatory irritable bowel syndrome. J. Gastroenterol., 46: 164-174.
    CrossRef  |  

  29. Pang, X.H., J.Y. Song, Y.J. Zhu, H.X. Xu, L.F. Huang and S.L. Chen, 2011. Applying plant DNA barcodes for Rosaceae species identification. Cladistics, 27: 165-170.
    CrossRef  |  

  30. Lin, G., J.Y. Wang, N. Li, M. Li and H. Gao et al., 2011. Hepatic sinusoidal obstruction syndrome associated with consumption of Gynura segetum. J. Hepatol., 54: 666-673.
    CrossRef  |  

  31. Zhou, Y., S. Lee, F.F.K. Choi, G. Xu and X. Liu et al., 2010. Qualitative and quantitative analysis of polycyclic polyprenylated acylphloroglucinols from Garcinia species using ultra performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry. Anal. Chim. Acta, 678: 96-107.
    CrossRef  |  

  32. Zhou, Y., N. Li, F.F.K. Choi, C.F. Qiao and J.Z. Song et al., 2010. A new approach for simultaneous screening and quantification of toxic pyrrolizidine alkaloids in some potential pyrrolizidine alkaloid-containing plants by using ultra performance liquid chromatography-tandem quadrupole mass spectrometry. Anal. Chim. Acta, 681: 33-40.
    CrossRef  |  

  33. Zhou, Y., F.F.K. Choi, Z.Z. He, J.Z. Song and C.F. Qiao et al., 2010. Optimisation of ultra-performance LC conditions using response surface methodology for rapid separation and quantitative determination of phenolic compounds in Artemisia minor. J. Sep. Sci., 33: 3675-3682.
    CrossRef  |  

  34. Yao, H., J. Song, C. Liu, K. Luo and J. Han et al., 2010. Use of ITS2 region as the universal DNA barcode for plants and animals. PLoS ONE., Vol. 5. 10.1371/journal.pone.0013102.
    CrossRef  |  Direct Link  |  

  35. Xu, G., W.L.T. Kan, Y. Zhou, J.Z. Song and Q.B. Han et al., 2010. Cytotoxic acylphloroglucinol derivatives from the twigs of Garcinia cowa. J. Nat. Prod., 73: 104-108.
    CrossRef  |  

  36. Song, J.Z., S.L. Li, Y. Zhou, C.F. Qiao, S.L. Chen and H.X. Xu, 2010. A novel approach to rapidly explore analytical markers for quality control of radix salviae miltiorrhizae extract granules by robust principal component analysis with ultra-high performance liquid chromatography-ultraviolet-quadrupole time-of-flight mass spectrometry. J. Pharm. Biomed. Anal., 53: 279-286.
    CrossRef  |  

  37. Song, J.Z., Q.B. Han, C.F. Qiao, P.P.H. But and H.X. Xu, 2010. Development and validation of a rapid capillary zone electrophoresis method for the determination of aconite alkaloids in aconite roots. Phytochem. Anal., 21: 137-143.
    CrossRef  |  

  38. Song, J.Z., L.M. Cheung, X. Liu, C.F. Qiao and Y. Zhou et al., 2010. Development and validation of an ultra high-performance liquid chromatographic method for the determination of a diastereomeric impurity in (+)-pinoresinol diglucoside chemical reference substance. J. Sep. Sci., 33: 1909-1915.
    CrossRef  |  

  39. Qin, H.Y., J.L. Luo, S.D. Qi, H.X. Xu, J.J.Y. Sung and Z.X. Bian, 2010. Visceral hypersensitivity induced by activation of transient receptor potential vanilloid type 1 is mediated through the serotonin pathway in rat colon. Eur. J. Pharmacol., 647: 75-83.
    CrossRef  |  

  40. Liu, X., T. Yu, X.M. Gao, Y. Zhou and C.F. Qiao et al., 2010. Apoptotic effects of polyprenylated benzoylphloroglucinol derivatives from the twigs of Garcinia multiflora. J. Nat. Prod., 73: 1355-1359.
    CrossRef  |  Direct Link  |  

  41. Liu, X., S.L. Li, Y. Zhou, J.Z. Song, Y.F. Zheng, G.P. Peng and H.X. Xu, 2010. Characterization of protostane triterpenoids in Alisma orientalis by Ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry. Rapid Commun. Mass Spectrom., 24: 1514-1522.
    CrossRef  |  

  42. Liu, L.Z., S.C.K. Cheung, L.L. Lan, S.K.S. Ho, H.X. Xu, J.C.N. Chan and P.C.Y. Tong, 2010. Berberine modulates insulin signaling transduction in insulin-resistant cells. Mol. Cell. Endocrinol., 317: 148-153.
    CrossRef  |  

  43. Liu, G.B., J.L. Xu, M. Geng, R. Xu and R.R. Hui et al., 2010. Synthesis of a novel series of diphenolic chromone derivatives as inhibitors of NO production in LPS-activated RAW264.7 macrophages. Bioorganic Med. Chem., 18: 2864-2871.
    CrossRef  |  

  44. Li, S.L., S.F. Lai, J.Z. Song, C.F. Qiao and X. Liu et al., 2010. Decocting-induced chemical transformations and global quality of Du-Shen-Tang, the decoction of ginseng evaluated by UPLC-Q-TOF-MS/MS based chemical profiling approach. J. Pharm. Biomed. Anal., 53: 946-957.
    CrossRef  |  

  45. Li, S.L., J.Z. Song, C.F. Qiao, Y. Zhou, K. Qian, K.H. Lee and H.X. Xu, 2010. A novel strategy to rapidly explore potential chemical markers for the discrimination between raw and processed Radix Rehmanniae by UHPLC-TOFMS with multivariate statistical analysis. J. Pharm. Biomed. Anal., 51: 812-823.
    CrossRef  |  

  46. Li, S.L., J.Z. Song, C.F. Qiao, Y. Zhou and H.X. Xu, 2010. UPLC-PDA-TOFMS based chemical profiling approach to rapidly evaluate chemical consistency between traditional and dispensing granule decoctions of traditional medicine combinatorial formulae. J. Pharm. Biomed. Anal., 52: 468-478.
    CrossRef  |  

  47. Hsieh, M.T., W.H. Peng, C.R. Wu, K.Y. Ng, C.L. Cheng and H.X. Xu, 2010. Review on experimental research of herbal medicines with anti-amnesic activity. Planta Med., 76: 203-217.
    Direct Link  |  

  48. Hoo, R.L.C., J.Y.L. Wong, C.F. Qiao, A. Xu, H.X. Xu and K.S.L. Lam, 2010. The effective fraction isolated from Radix Astragali alleviates glucose intolerance, insulin resistance and hypertriglyceridemia in db/db diabetic mice through its anti-inflammatory activity. Nutr. Metab., Vol. 7. 10.1186/1743-7075-7-67.
    CrossRef  |  

  49. Han, Q.B., T. Yu, F. Lai, Y. Zhou and C. Feng et al., 2010. Quick identification of apoptosis inducer from Isodon eriocalyx by a drug discovery platform composed of analytical high-speed counter-current chromatography and the fluorescence-based caspase-3 biosensor detection. Talanta, 82: 1521-1527.
    Direct Link  |  

  50. Gao, X.M., T. Yu, F.S.F. Lai, Y. Zhou and X. Liu et al., 2010. Identification and evaluation of apoptotic compounds from Garcinia paucinervis. Bioorg. Med. Chem., 18: 4957-4964.
    CrossRef  |  

  51. Gao, X.M., T. Yu, F.S.F. Lai, J.X. Pu and C.F. Qiao et al., 2010. Novel polyisoprenylated benzophenone derivatives from Garcinia paucinervis. Tetrahedron Lett., 51: 2442-2446.
    CrossRef  |  

  52. Gao, T., H. Yao, J.Y. Song, C. Liu and Y.J. Zhu et al., 2010. Identification of medicinal plants in the family Fabaceae using a potential DNA barcode ITS2. J. Ethnopharmacol., 130: 116-121.
    CrossRef  |  Direct Link  |  

  53. Cheng, H.Y., M.T. Hsieh, F.S. Tsai, C.R. Wu and C.S. Chiu et al., 2010. Neuroprotective effect of luteolin on amyloid β Protein (25-35)-induced toxicity in cultured rat cortical neurons. Phytotherapy Res., 24: S102-S108.

  54. Cheng, C.L., K.Y. Ng and H.X. Xu, 2010. Recent advances in the discovery of novel anti-herpetic agents from Chinese herbal medicines. Curr. Org. Chem., 14: 1714-1726.
    CrossRef  |  

  55. Bian, Z.X., M. Zhang, Q.B. Han, H.X. Xu and J.J.Y. Sung, 2010. Analgesic effects of JCM-16021 on neonatal maternal separation-induced visceral pain in rats. World J. Gastroenterol., 16: 837-845.
    Direct Link  |  

  56. Zhou, Y., S.X. Huang, J.Z. Song, C.F. Qiao, S.L. Li, Q.B. Han and H.X. Xu, 2009. Screening of polycyclic polyprenylated acylphloroglucinols from Garcinia species using Precursor Ion Discovery (PID) scan and ultra performance liquid chromatography electrospray ionization Q-TOF tandem mass spectrometry. J. Am. Soc. Mass Spectrom., 20: 1846-1850.
    CrossRef  |  

  57. Zhou, Y., J.Z. Song, F.F.K. Choi, H.F. Wu and C.F. Qiao et al., 2009. An experimental design approach using response surface techniques to obtain optimal liquid chromatography and mass spectrometry conditions to determine the alkaloids in Meconopsi species. J. Chromatogr. A, 1216: 7013-7023.
    CrossRef  |  

  58. Zhou, Y., G. Xu, F.F.K. Choi, L.S. Ding and Q.B. Han et al., 2009. Qualitative and quantitative analysis of diterpenoids in Salvia species by liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry. J. Chromatogr. A, 1216: 4847-4858.
    CrossRef  |  

  59. Zhou, Y., B.L. Yang, J. Yang, S.X. Huang, H.D. Sun, H.X. Xu and L.S. Ding, 2009. Electrospray ionization tandem mass spectrometric analysis of ent-6,7-seco-kaurane diterpenoids from the Isodon species. Rapid Commun. Mass Spectrom., 23: 138-146.
    CrossRef  |  

  60. Zhang, X.J., H.L. Chen, Z. Li, H.Q. Zhang, H.X. Xu, J.J.Y. Sung and Z.X. Bian, 2009. Analgesic effect of paeoniflorin in rats with neonatal maternal separation-induced visceral hyperalgesia is mediated through adenosine A1 receptor by inhibiting the extracellular signal-regulated protein kinase (ERK) pathway. Pharmacol. Biochem. Behav., 94: 88-97.
    CrossRef  |  

  61. Ying, N.G.K., C.L. Cheng and H.X. Xu, 2009. Safety issues of Chinese medicine: A review of intoxication cases in Hong Kong. Chinese Herbal Med., 1: 29-39.

  62. Yao, H., J.Y. Song, X.Y. Ma, C. Liu and Y. Li et al., 2009. Identification of dendrobium species by a candidate DNA barcode sequence: The chloroplast psbA-trnH intergenic region. Planta Med., 75: 667-669.
    CrossRef  |  

  63. Wang, X., Y. Chen, Q.B. Han, C.Y. Chan and H. Wang et al., 2009. Proteomic identification of molecular targets of gambogic acid: Role of stathmin in hepatocellular carcinoma. Proteomics, 9: 242-253.
    CrossRef  |  PubMed  |  

  64. Song, J.Z., C.F. Qiao, S.L. Li, Y. Zhou, M.T. Hsieh and H.X. Xu, 2009. Rapid optimization of dual-mode gradient high performance liquid chromatographic separation of radix et rhizoma salviae miltiorrhizae by response surface methodology. J. Chromatogr. A, 1216: 7007-7012.
    CrossRef  |  

  65. Song, J.Z., C.F. Qiao, S.L. Li, Q.B. Han and H.X. Xu, 2009. Quality assessment of granule of danshen extract by high performance liquid chromatography. Chinese J. Nat. Med., 7: 368-375.
    CrossRef  |  

  66. Qi, S.D., S.L. Tian, H.X. Xu, J.J.Y. Sung and Z.X. Bian, 2009. Quantification of luminally released serotonin in rat proximal colon by capillary electrophoresis with laser-induced fluorescence detection. Anal. Bioanal. Chem., 393: 2059-2066.
    CrossRef  |  

  67. Liu, G.B., J.L. Xu, C.C. He, G. Chen, Q. Xu, H.X. Xu and J.X. Li, 2009. Synthesis and evaluation of a novel series of quinoline derivatives with immunosuppressive activity. Bioorg. Med. Chem., 17: 5433-5441.
    CrossRef  |  

  68. Li, Z., X.J. Zhang, H.X. Xu, J.J.Y. Sung and Z.X. Bian, 2009. Intracolonical administration of protease-activated receptor-2 agonists produced visceral hyperalgesia by up-regulating serotonin in the colon of rats. Eur. J. Pharmacol., 606: 199-204.
    CrossRef  |  

  69. Li, S.L., J.Z. Song, F.F.K. Choi, C.F. Qiao, Y. Zhou, Q.B. Han and H.X. Xu, 2009. Chemical profiling of Radix Paeoniae evaluated by ultra-performance liquid chromatography/photo-diode-array/quadrupole time-of-flight mass spectrometry. J. Pharm. Biomed. Anal., 49: 253-266.
    CrossRef  |  

  70. Li, C.Y., H.X. Xu, Q.B. Han and T.S. Wu, 2009. Quality assessment of Radix Codonopsis by quantitative nuclear magnetic resonance. J. Chromatogr. A, 1216: 2124-2129.
    CrossRef  |  

  71. Huang, S.X., C. Feng, Y. Zhou, G. Xu and Q.B. Han et al., 2009. Bioassay-guided isolation of xanthones and polycyclic prenylated acylphloroglucinols from Garcinia oblongifolia. J. Nat. Prod., 72: 130-135.
    Direct Link  |  

  72. Han, Q.B., Y. Zhou, C. Feng, G. Xu and S.X. Huang et al., 2009. Bioassay guided discovery of apoptosis inducers from gamboge by high-speed counter-current chromatography and high-pressure liquid chromatography/electrospray ionization quadrupole time-of-flight mass spectrometry. J. Chromatogr. B, 877: 401-407.
    CrossRef  |  

  73. Han, Q.B. and H.X. Xu, 2009. Caged Garcinia xanthones: Development since 1937. Curr. Med. Chem., 16: 3775-3796.
    Direct Link  |  

  74. Chung, E.K.Y., Z.X. Bian, H.X. Xu and J.J.Y. Sung, 2009. Neonatal maternal separation increases brain-derived neurotrophic factor and tyrosine kinase receptor B expression in the descending pain modulatory system. Neurosignals, 17: 213-221.
    Direct Link  |  

  75. Chen, H.L., X.J. Zhang, S.D. Qi, H.X. Xu, J.J. Sung and Z.X. Bian, 2009. Simultaneous determination of glutamate and aspartate in rat periaqueductal gray matter microdialysates by capillary electrophoresis with laser-induced fluorescence. J. Chromatogr. B, 877: 3248-3252.
    Direct Link  |  

  76. Bian, Z.X., Z. Li, Z.X. Huang, M. Zhang, H.L. Chen, H.X. Xu and J.J.Y. Sung, 2009. Unbalanced expression of protease-activated receptors-1 and -2 in the colon of diarrhea-predominant irritable bowel syndrome patients. J. Gastroenterol., 44: 666-674.

  77. Zhou, Y., S.Y. Jiang, L.S. Ding, S.W. Cheng, H.X. Xu, P.P.H. But and P.C. Shaw, 2008. Chemical fingerprinting of medicinal plants Gui-jiu by LC-ESI Multiple-Stage MS. Chromatographia, 68: 781-789.
    CrossRef  |  

  78. Zhou, Y., Q.B. Han, J.Z. Song and H.X. Xu, 2008. Characterization of polyprenylated xanthones in Garcinia xipshuanbannaensis using liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry. J. Chromatogr. A, 1206: 131-139.
    CrossRef  |  PubMed  |  

  79. Zhou, Y., X. Liu, J. Yang, Q.B. Han and J.Z. Song et al., 2008. Analysis of caged xanthones from the resin of Garcinia hanburyi using ultr-aperformance liquid chromatography/electrospray ionization quadrupole time-of-flight tandem mass spectrometry. Anal. Chimica Acta, 629: 104-118.
    CrossRef  |  

  80. Zhang, X.J., Z. Li, W.M. Leung, L. Liu, H.X. Xu and Z.X. Bian, 2008. The analgesic effect of paeoniflorin on neonatal maternal separation-induced visceral hyperalgesia in rats. J. Pain, 9: 497-505.
    CrossRef  |  PubMed  |  

  81. Zhang, S.Y., G. Chen, P.F. Wei, X.S. Huang andY. Dai et al., 2008. The effect of puerarin on serum nitric oxide concentration and myocardial eNOS expression in rats with myocardial infarction. J. Asian Nat. Prod. Res., 10: 323-328.
    CrossRef  |  PubMed  |  

  82. Yi, L.T., Y.C. Li, Y. Pan, J.M. Li and Q. Xu et al., 2008. Antidepressant-like effects of psoralidin isolated from the seeds of Psoralea Corylifolia in the forced swimming test in mice. Prog. Neuropsychopharmacol. Biol. Psychiatry, 32: 510-519.
    CrossRef  |  PubMed  |  

  83. Xu, Q., Y. Pan, L.T. Yi, Y.C. Li, S.F. Mo and F.X. Jiang et al., 2008. Antidepressant-like effects of psoralen isolated from the seeds of psoralea corylifolia in the mouse forced swimming test. Biol. Pharm. Bull., 31: 1109-1114.
    PubMed  |  

  84. Xu, G., L.Y. Peng, A.J. Hou, J. Yang, Q.B. Han, H.X. Xu and Q.S. Zhao, 2008. Isolation, structural elucidation, and chemical transformation of interconvertible 8,12-hemiketal germacranolide sesquiterpenoids from Salvia castanea Diels f. tomentosa Stib. Tetrahedron, 64: 9490-9494.
    CrossRef  |  

  85. Xu, G., C. Feng, Y. Zhou, Q.B. Han and C.F. Qiao et al., 2008. Bioassay and UPLC/MS guided isolation of apoptosis-inducing benzophenones and xanthone from the pericarp of Garcinia yunnanensis Hu. J. Agric. Food Chem., 56: 11144-11150.

  86. Xie, Y., H. Zhou, Y.F. Wong, Z.Q. Liu, H.X. Xu, Z.H. Jiang and L. Liu, 2008. An optimized High-Performance Liquid Chromatography (HPLC) method for benzoylmesaconine determination in Radix Aconiti Lateralis Preparata (Fuzi, aconite roots) and its products. Chinese Med., Vol. 3. .
    Direct Link  |  

  87. Xie, Y., H. Zhou, Y.F. Wong, H.X. Xu, Z.H. Jiang and L. Liu, 2008. Study on the pharmacokinetics and metabolism of paeonol in rats treated with pure paeonol and an herbal preparation containing paeonol by using HPLC-DAD-MS method. J. Pharm. Biomed. Anal., 46: 748-756.
    CrossRef  |  PubMed  |  

  88. Wong, Y.F., H. Zhou, J.R. Wang, Y.Xie, H.X. Xu and L. Liu, 2008. Anti-inflammatory and analgesic effects and molecular mechanisms of JCICM-6, a purified extract derived from an anti-arthritic Chinese herbal formula. Phytomedicine, 15: 416-426.
    CrossRef  |  PubMed  |  

  89. Song, J.Z., H.W.H. Yiu, C.F. Qiao, Q.B. Han and H.X. Xu, 2008. Chemical comparison and classification of Radix Astragali by determination of isoflavonoids and astragalosides. J. Pharm. Biomed. Anal., 47: 399-406.
    CrossRef  |  PubMed  |  

  90. Song, J.Z., C.F. Qiao, S.L. Li, Q.B. Han and H.X. Xu, 2008. Purity determination of yunaconitine reference standard using HPLC with experimental design and response surface optimization. J. Separat. Sci., 31: 3809-3816.
    CrossRef  |  PubMed  |  

  91. Li, S.L., J.Z. Song, Q.B. Han, C.F. Qiao and H.X. Xu, 2008. Improved high-performance liquid chromatographic method for simultaneous determination of 12 cytotoxic caged xanthones in gamboges, a potential anticancer resin from Garcinia hanburyi. Biomed. Chromatogr., 22: 637-644.
    CrossRef  |  PubMed  |  

  92. Li, S., Q. Han, C. Qiao, J. Song, C.L. Cheng and H. Xu, 2008. Chemical markers for the quality control of herbal medicines: An overview. Chin. Med., 3: 7-7.
    CrossRef  |  PubMed  |  Direct Link  |  

  93. Huang, S.X., Q.B. Han, C. Lei, J.X. Pu and W.L. Xiao et al., 2008. Isolation and characterization of miscellaneous terpenoids of Schisandra chinensis. Tetrahedron, 64: 4260-4267.
    CrossRef  |  

  94. Han, Q.B., S.L. Li, C.F. Qiao, J.Z. Song and Z.W. Cai et al., 2008. A simple method to identify the unprocessed Strychnos seeds used in herbal medicinal products. Planta Medica, 74: 458-463.
    PubMed  |  

  95. Han, Q.B., N.Y. Yang, H.L. Tian, C.F. Qiao and J.Z. Song et al., 2008. Xanthones with growth inhibition against HeLa cells from Garcinia xipshuanbannaensis. Phytochemistry, 69: 2187-2192.
    CrossRef  |  PubMed  |  Direct Link  |  

  96. Han, Q.B., L. Wong, N.Y. Yang, J.Z. Song and C.F. Qiao et al., 2008. A simple method to optimize the HSCCC two-phase solvent system by predicting the partition coefficient for target compound. J. Separat. Sci., 31: 1189-1194.
    CrossRef  |  PubMed  |  

  97. Han, Q.B., H.L. Tian, N.Y. Yang, C.F. Qiao and J.Z. Song et al., 2008. Polyprenylated xanthones from Garcinia lancilimba showing apoptotic effects against HeLa-C3 cells. Chem. Biodivers., 5: 2710-2717.
    CrossRef  |  

  98. Chen, Y.C., Y.T. Cheung, L.D. Kong, T.B. Ng, C.F. Qiao, S.F. Mo, H.X. Xu and H.F. Kung, 2008. Transcriptional regulation of corticotrophin releasing factor gene by furocoumarins isolated from seeds of Psoralea corylifolia. Life Science, 82: 1117-1121.
    CrossRef  |  PubMed  |