Hi, I am Xiang Yang Zhang, My LiveDNA is 86.6445
 
   
  Home
 
 
 
Dr. Xiang Yang Zhang
 
Highest Degree: Ph.D. in Psychopharmacology from Peking University School of Medicine, China
 
Institute: Baylor College of Medicine, USA
 
Area of Interest: Pharmacology and Toxicology
  •   Psychiatry Research
  •   Psychopharmacology
  •   Alcoholism
  •   Human Genetics
 
URL: http://livedna.org/86.6445
 
My SELECTED Publications
1:   Aggarwal, N.K., X.Y. Zhang, E. Stefanovics, D.C. Chen, M.H. Xiu, K. Xu and R.A. Rosenheck, 2012. Rater evaluations for psychiatric instruments and cultural differences: The positive and negative syndrome scale in China and the United States. J. Nervous Mental Dis., 200: 814-820.
CrossRef  |  PubMed  |  
2:   An, H.M., Y.L. Tan, J. Shi, Z.R. Wang and J. Li et al., 2013. Extract of Ginkgo biloba is equivalent to vitamin E in attenuating and preventing vacuous chewing movements in a rat model of tardive dyskinesia. Behav. Pharmacol. .
PubMed  |  
3:   Cao, C., L. Wang, R. Wang, C. Dong, Y. Qing, X.Y. Zhang and J. Zhang, 2013. Stathmin genotype is associated with reexperiencing symptoms of posttraumatic stress disorder in Chinese earthquake survivors. Prog. Neurops. Biol. Psyc., 44: 296-300.
CrossRef  |  
4:   Cao, J.X., J. Hu, X.M. Ye, Y. Xia, C.A. Haile, T.R. Kosten and X.Y. Zhang, 2011. Association between the 5-HTR1B gene polymorphisms and alcohol dependence in a Han Chinese population. Brain Res., 1376: 1-9.
CrossRef  |  Direct Link  |  
5:   Chen da, C., J. Wang, B. Wang, S.C. Yang and C.X. Zhang et al., 2009. Decreased levels of serum brain-derived neurotrophic factor in drug-naive first-episode schizophrenia: Relationship to clinical phenotypes. Psychopharmacology, 207: 375-380.
6:   Chen da, C., L.Y. Qi, M.H. Xiu, L.Y. Cao and F. Wang et al., 2008. Elevated serum levels of tumor necrosis factor-alpha in clozapine-associated obesity in chronic schizophrenia. Schizophrenia Res., 106: 367-368.
CrossRef  |  PubMed  |  
7:   Chen da, C., M.A. Zhou, D.H. Zhou, M.H. Xiu, G.Y. Wu, T.R. Kosten and X.Y. Zhang, 2011. Gender differences in the prevalence of diabetes mellitus in chronic hospitalized patients with schizophrenia on long-term antipsychotics. Psychiatry Res., 186: 451-453.
CrossRef  |  PubMed  |  
8:   Chen, D.C., M.H. Xiu, H. Liu, B.S. Zhang, Y. Wang, T.R. Kosten and X.Y. Zhang, 2010. Reduced status of plasma total antioxidant capacity in schizophrenia with tardive dyskinesia. J. Psychiatric Res., 44: 1111-1112.
CrossRef  |  PubMed  |  
9:   Chen, J.X., Y.A. Su, S.L. Wang, Q.T. Bian and Y.H. Liu et al., 2009. Aripiprazole treatment of risperidone-induced hyperprolactinemia. J. Clin. Psychiatry, 70: 1058-1059.
PubMed  |  
10:   Guo, S., F. da Chen, D.F. Zhou, H.Q. Sun and G.Y. Wu et al., 2007. Association of functional catechol O-methyl transferase (COMT) Val108Met polymorphism with smoking severity and age of smoking initiation in Chinese male smokers. Psychopharmacology, 190: 449-456.
CrossRef  |  PubMed  |  Direct Link  |  
11:   Haile, C.N., X.Y. Zhang, F. Carroll and T.A. Kosten, 2005. Cocaine self-administration and locomotor activity are altered in Lewis and F344 inbred rats by RTI 336, a 3-phenyltropane analog that binds to the dopamine transporter. Brain Res., 1055: 186-195.
CrossRef  |  
12:   Han, M., X.F. Huang, D.C. Chen, M. Xiu, T.R. Kosten and X.Y. Zhang, 2013. Diabetes and cognitive deficits in chronic schizophrenia: A case-control study. PLoS One, Vol. 8. 10.1371/journal.pone.0066299.
CrossRef  |  
13:   Han, M., X.F. Huang, D.C. Chen, M.H. Xiu and L. Hui et al., 2012. Gender differences in cognitive function of patients with chronic schizophrenia. Prog. Neuropsychopharmacol. Biol. Psychiatry, 539: 558-563.
CrossRef  |  PubMed  |  
14:   He, J., Y. Xie, J. Tao, H. Su and W. Wu et al., 2013. Gender differences in socio-demographic and clinical characteristics of methamphetamine inpatients in a Chinese population. Drug Alcohol Depend., 130: 94-100.
CrossRef  |  
15:   Hui, L., X. Zhang, X.F. Huang, M. Han, F. Fernandez et al., 2012. The dopamine b-hydroxylase 19 bp insertion/deletion polymorphism was associated with first-episode but not medicated chronic schizophrenia. J. Psyc. Res., 46: 733-737.
CrossRef  |  PubMed  |  
16:   Hui, L., X. Zhang, Y.Q. Yu, M. Han and X.F. Huang et al., 2013. Association between DBH 19 bp insertion/deletion polymorphism and cognition in first-episode schizophrenic patients. Schizophr. Res., 147: 236-240.
17:   Kosten, T.A. and X.Y. Zhang, 2008. Sex differences in non-reinforced responding for cocaine. Am. J. Drug Alcohol Abuse, 34: 473-488.
CrossRef  |  PubMed  |  
18:   Kosten, T.A., H. Sanchez, X.Y. Zhang and P. Kehoe, 2004. Neonatal isolation enhances acquisition of cocaine self-administration and food responding in female rats. Behav. Brain Res., 151: 137-149.
PubMed  |  
19:   Kosten, T.A., X.Y. Zhang and P. Kehoe, 2003. Chronic neonatal isolation stress enhances cocaine-induced increases in ventral striatal dopamine levels in rat pups. Dev. Brain Res., 141: 109-116.
CrossRef  |  
20:   Kosten, T.A., X.Y. Zhang and P. Kehoe, 2004. Infant rats with chronic neonatal isolation experience show decreased extracellular serotonin levels in ventral striatum at baseline and in response to cocaine. Dev. Brain Res., 152: 19-24.
CrossRef  |  
21:   Kosten, T.A., X.Y. Zhang and P. Kehoe, 2005. Heightened cocaine and food self-administration in female rats with neonatal isolation experience. Neuropsychopharmacology, 31: 70-76.
CrossRef  |  
22:   Kosten, T.A., X.Y. Zhang and P. Kehoe, 2005. Neurochemical and behavioral responses to cocaine in adult male rats with neonatal isolation experience. J. Pharmacol. Exp. Ther., 314: 661-667.
CrossRef  |  
23:   Li, S.X., J. Li, D.H. Epstein, X.Y. Zhang, T.R. Kosten and L. Lu, 2008. Serum cortisol secretion during heroin abstinence is elevated only nocturnally. Am. J. Drug Alcohol Abuse, 34: 321-328.
CrossRef  |  PubMed  |  
24:   Li, S.X., J. Shi, D.H. Epstein, X. Wang and X.L. Zhang et al., 2009. Circadian alteration in neurobiology during 30 days of abstinence in heroin users. Biol. Psychiatry, 65: 905-912.
CrossRef  |  PubMed  |  
25:   Li, S.X., L.J. Liu, W.G. Jiang, L.L. Sun and S.J. Zhou et al., 2010. Circadian alteration in neurobiology during protracted opiate withdrawal in rats. J. Neurochem., 115: 353-362.
CrossRef  |  PubMed  |  
26:   Li, W., J. Wei, D.F. Zhou, Y.L. Tan and Y.L. Cao et al., 2007. Lack of association between the BDNF C270T polymorphism and schizophrenia in a Chinese Han population. Schizophr. Res., 97: 297-298.
CrossRef  |  PubMed  |  Direct Link  |  
27:   Li, W., N. Zhou, Q. Yu, X. Li and Y. Yu et al., 2013. Association of BDNF gene polymorphisms with schizophrenia and clinical symptoms in a Chinese population. Am. J. Med. Genet. Part B, 162: 538-545.
CrossRef  |  Direct Link  |  
28:   Li, W.J., C.G. Kou, Y. Yu, S. Sun, X. Zhang, T.R. Kosten and X.Y. Zhang, 2012. Association of Catechol-O-methyltransferase gene polymorphisms with schizophrenia and negative symptoms in a Chinese population. Am. J. Med. Gen. Part B. Neurops. Gen., 159B: 370-375.
CrossRef  |  PubMed  |  
29:   Li, X.F., Y.L. Zheng, M.H. Xiu, C. Chen da, T.R. Kosten and X.Y. Zhang, 2011. Reduced plasma total antioxidant status in first-episode drug-naive patients with schizophrenia. Prog. Neuropsychopharmacol. Biol. Psychiatry, 35: 1064-1067.
CrossRef  |  PubMed  |  
30:   Li, Y.Q., X.Y. Wang, H.F. Zhai, X.Y. Zhang, T. Kosten and L. Lu, 2008. Sex- and age-dependent effects of early postnatal sibling deprivation on spatial learning and memory in adult rats. Behav. Brain Res., 186: 138-142.
CrossRef  |  PubMed  |  
31:   Li, Y.Q., X.Y. Wang, H.F. Zhai, Y.Q. Zheng, X.Y. Zhang, T. Kosten and L. Lu, 2008. Effects of early postnatal sibling deprivation on anxiety and vulnerability to cocaine in offspring rats. Psychopharmacology, 199: 245-253.
CrossRef  |  
32:   Liu, H., C. Wang, P.H. Chen, B.S. Zhang and Y.L. Zheng et al., 2010. Association of the manganese superoxide dismutase gene Ala-9Val polymorphism with clinical phenotypes and tardive dyskinesia in schizophrenic patients. Prog. Neuropsychopharmacol. Biol. Psychiatry, 34: 692-696.
CrossRef  |  Direct Link  |  
33:   Liu, H., Y. Kang, J. Liang, C. Li and M. Xiu et al., 2012. Lower serum interleukin-2 levels in schizophrenic patients with tardive dyskinesia. Psychiat. Res., 198: 329-331.
CrossRef  |  Direct Link  |  
34:   McIntosh. B.J., X.Y. Zhang, T. Kosten, S.P. Tan, M.H. Xiu, J. Rakofsky and P.D. Harvey, 2011. Performance-based assessment of functional skills in severe mental illness: Results of a large-scale study in China. J. Psychiatric Res., 45: 1089-1094.
CrossRef  |  Direct Link  |  
35:   Qi, L.Y., M.H. Xiu, C. Chen da, F. Wang, T.A. Kosten, T.R. Kosten and X.Y. Zhang, 2009. Increased serum S100B levels in chronic schizophrenic patients on long-term clozapine or typical antipsychotics. Neurosci. Lett., 462: 113-117.
CrossRef  |  PubMed  |  
36:   Qi, Y.K., Y.T. Xiang, F.R. An, J. Wang amd J.Y. Zeng et al., 2014. Nurses work-related stress in China: A comparison between psychiatric and general hospitals. Perspect. Psychiatr. Care, 50: 27-32.
CrossRef  |  Direct Link  |  
37:   Qiu, H.T., H.Q. Meng, C. Song, M.H. Xiu and D.C. Chen et al., 2009. Association between monoamine oxidase (MAO)-A gene variants and schizophrenia in a Chinese population. Brain Res., 1287: 67-73.
CrossRef  |  Direct Link  |  
38:   Ren, Z.Y., X.L. Zhang, Y. Liu, L.Y. Zhao and J. Shi et al., 2009. Diurnal variation in cue-induced responses among protracted abstinent heroin users. Pharmacol. Biochem. Behav., 91: 468-472.
CrossRef  |  
39:   Shi, J., S.X. Li, X.L. Zhang, X. Wang, B. Le Foll et al., 2009. Time-dependent neuroendocrine alterations and drug craving during the first month of abstinence in heroin addicts. Am. J. Drug Alcohol Abuse, 35: 267-272.
CrossRef  |  
40:   Shi, J., W. Jun, L.Y. Zhao, Y.X. Xue and X.Y. Zhang et al., 2009. Effect of rapamycin on cue-induced drug craving in abstinent heroin addicts. Eur. J. Pharmacol., 615: 108-112.
CrossRef  |  Direct Link  |  
41:   Shi, W.X., X.Y. Zhang, C.L. Pun and B.S. Bunney, 2007. Clozapine blocks D-amphetamine-induced excitation of dopamine neurons in the ventral tegmental area. Neuropsychopharmacology, 32: 1922-1928.
CrossRef  |  PubMed  |  Direct Link  |  
42:   Song, C., X.Y. Zhang and M. Manku, 2009. Increased phospholipase A2 activity and inflammatory response but decreased nerve growth factor expression in the olfactory bulbectomized rat model of depression: effects of chronic ethyl-eicosapentaenoate treatment. J. Neurosci., 29: 14-22.
CrossRef  |  Direct Link  |  
43:   Sun, H., F. Wang, H. Fan, Q. Yan and K. Cui et al., 2013. The interaction of polymorphisms of IL10 and DBH was associated with general symptoms of PANSS with TD in Chinese Han schizophrenic patients. PLoS One, Vol. 8. 10.1371/journal.pone.0070963.
CrossRef  |  PubMed  |  
44:   Sun, H., S. Guo, D. Chen, F. Yang and Y. Zou et al., 2012. Association of functional COMT Val108/Met polymorphism with smoking cessation in a nicotine replacement therapy. J. Neural Trans., 119: 1491-1498.
CrossRef  |  
45:   Sun, H.Q., S. Guo, D.F. Chen, Z.N. Jiang and Y. Liu et al., 2009. Family support and employment as predictors of smoking cessation success: A randomized, double-blind, placebo-controlled trial of nicotine sublingual tablets in Chinese smokers. Am. J. Drug Alcohol Abuse, 35: 183-188.
CrossRef  |  PubMed  |  
46:   Sun, S., F. Wang, J. Wei, L.Y. Cao and G.Y. Wu et al., 2008. Association between interleukin-3 receptor alpha polymorphism and schizophrenia in the Chinese population. Neurosci. Lett., 440: 35-37.
CrossRef  |  Direct Link  |  
47:   Sun, S., F. Wang, J. Wei, L.Y. Cao and L.Y. Qi et al., 2008. Association between interleukin-6 receptor polymorphism and patients with schizophrenia. Schizophrenia Res., 102: 346-347.
CrossRef  |  PubMed  |  
48:   Sun, S., J. Wei, H. Li, S. Jin and P. Li et al., 2009. A family-based study of the IL3RA gene on susceptibility to schizophrenia in a Chinese Han population. Brain Res., 1268: 13-16.
CrossRef  |  Direct Link  |  
49:   Tan, Y.L., D.F. Zhou and X.Y. Zhang, 2005. Decreased plasma brain-derived neurotrophic factor levels in schizophrenic patients with tardive dyskinesia: Association with dyskinetic movements. Schizophrenia Res., 74: 263-270.
CrossRef  |  
50:   Tan, Y.L., D.F. Zhou, L.Y. Cao, Y.Z. Zou and X.Y. Zhang, 2005. Decreased BDNF in serum of patients with chronic schizophrenia on long-term treatment with antipsychotics. Neurosci. Lett., 382: 27-32.
CrossRef  |  
51:   Tan, Y.L., D.F. Zhou, L.Y. Cao, Y.Z. Zou, G.Y. Wu and X.Y. Zhang, 2005. Effect of the BDNF Val66Met genotype on episodic memory in schizophrenia. Schizophrenia Res., 77: 355-356.
CrossRef  |  
52:   Wang, F., H. Fan, H. Sun, F. Yang and Y. Luo et al., 2012. Association between TNF-α promoter -308A/G polymorphism and tardive dyskinesiain Chinese Han patients with schizophrenia. Prog. Neuropsychopharmacol. Biol. Psychiatry, 37: 106-110.
53:   Wang, F., M.H. Xiu, D.F. Zhou, L.Y. Cao, G.Y. Wu et al., 2008. The CCR5 32-bp deletion allele is rare in a Chinese population. Schizophrenia Res., 101: 341-343.
CrossRef  |  PubMed  |  
54:   Wang, L., C. Cao, R. Wang, Y. Qing, J. Zhang and X.Y. Zhang, 2013. PAC1 receptor (ADCYAP1R1) genotype is associated with PTSD's emotional numbing symptoms in Chinese earthquake survivors. J. Affect. Disord., 150: 156-159.
CrossRef  |  PubMed  |  Direct Link  |  
55:   Wang, Y., J.D. Wang, H.R. Wu, B.S. Zhang and H. Fang et al., 2010. The Val66Met polymorphism of the brain-derived neurotrophic factor gene is not associated with risk for schizophrenia and tardive dyskinesia in Han Chinese population. Schizophrenia Res., 120: 240-242.
CrossRef  |  PubMed  |  
56:   Wang, Z.R., D.F. Zhou, L.Y. Cao, Y.L. Tan, J. Li et al., 2007. Brain-derived neurotrophic factor polymorphisms and smoking in schizophrenia. Schizophrenia Res., 97: 299-301.
57:   Wu, J.Q., C da Chen, Y.L. Tan, S.P. Tan and Z.R. Wang et al., 2014. Cognition impairment in schizophrenia patients with tardive dyskinesia: Association with plasma superoxide dismutase activity. Schizophr. Res., 152: 210-216.
CrossRef  |  PubMed  |  Direct Link  |  
58:   Wu, J.Q., D.C. Chen, M.H. Xiu, Y.L. Tan, F.D. Yang, T.R. Kosten and X.Y. Zhang, 2013. Tardive dyskinesia is associated with greater cognitive impairment in schizophrenia. Prog. Neuropsychopharmacol. Biol. Psychiatry, 46: 71-77.
CrossRef  |  PubMed  |  Direct Link  |  
59:   Wu, J.Q., T.R. Kosten and X.Y. Zhang, 2013. Free radicals, antioxidant defense systems and schizophrenia. Prog. Neuropsychopharmacol. Biol. Psychiatry, 46: 200-206.
CrossRef  |  PubMed  |  Direct Link  |  
60:   Wu, Z., X.Y. Zhang, H. Wang, W. Tang and Y. Xia et al., 2012. Elevated plasma superoxide dismutase in first-episode and drug naive patients with schizophrenia: Inverse association with positive symptoms. Prog. Neuropsychopharmacol. Biol. Psychiatry, 36: 34-38.
CrossRef  |  Direct Link  |  
61:   Xiang, Y.T., L.J. Li, J.J. Zhou, C.Y. Wang and L.B. Dixon et al., 2014. Quality of life of patients with euthymic bipolar disorder and its associations with demographic and clinical characteristics, psychopathology and cognitive deficits. Perspect. Psychiatr. Care, 50: 44-50.
CrossRef  |  Direct Link  |  
62:   Xiu, M.H., D.C. Chen, D. Wang, K. Zhang and A. Dong et al., 2012. Elevated interleukin-18 serum levels in chronic schizophrenia: Association with sychopathology. J. Psyc. Res., 46: 1093-1098.
CrossRef  |  PubMed  |  
63:   Xiu, M.H., L. Hui, Y.F. Dang, T.D. Hou and C.X. Zhang et al., 2009. Decreased serum BDNF levels in chronic institutionalized schizophrenia on long-term treatment with typical and atypical antipsychotics. Prog. Neuropsychopharmacol. Biol. Psychiatry, 33: 1508-1512.
64:   Xiu, M.H., S. Chen, F. Wang, L.Y. Cao and L.Y. Qi et al., 2008. Altered interleukin-3 serum levels in drug-naive and neuroleptic-treated schizophrenic patients. Schizophrenia Res., 106: 369-370.
CrossRef  |  PubMed  |  
65:   Yang, F.D., X.Q. Wang, X.P. Liu, K.X. Zhao and W.H. Fu et al., 2011. Sex difference in QTc prolongation in chronic institutionalized patients with schizophrenia on long-term treatment with typical and atypical antipsychotics. Psychopharmacology, 216: 9-16.
CrossRef  |  PubMed  |  
66:   Yang, Y.Q., S. Sun, Y.Q. Yu, W.J. Li and X. Zhang et al., 2011. Decreased serum brain-derived neurotrophic factor levels in schizophrenic patients with tardive dyskinesia. Neurosci. Lett., 502: 37-40.
CrossRef  |  Direct Link  |  
67:   Zhang, X.Y., C. da Chen, M.H. Xiu, F.D. Yang and Y.L. Tan et al., 2013. Thioredoxin, a novel oxidative stress marker and cognitive performance in chronic and medicated schizophrenia versus healthy controls. Schizophrenia Res., 143: 301-306.
CrossRef  |  PubMed  |  
68:   Zhang, R., Q. Miao, C. Wang, R. Zhao and W. Li et al., 2013. Genome-wide DNA methylation analysis in alcohol dependence in a male Chinese population. Addictive Biol., 18: 392-403.
69:   Zhang, R., W. Hao, M. Pan, C. Wang and X. Zhang et al., 2011. The prevalence and clinical-demographic correlates of diabetes mellitus in chronic schizophrenic patients receiving clozapine. Human Psychopharmacol., 26: 392-396.
CrossRef  |  Direct Link  |  
70:   Zhang, W.F., Y.L. Tan, X.Y. Zhang, R.C. Chan, H.R. Wu and D.F. Zhou, 2011. Extract of Ginkgo biloba treatment for tardive dyskinesia in schizophrenia: A randomized, double-blind, placebo-controlled trial. J. Clin. Psychiatry, 72: 615-621.
CrossRef  |  PubMed  |  Direct Link  |  
71:   Zhang, X., L. Hui, Y. Liu, Z.Q. Wang and Y. You et al., 2013. The type 2 diabetes mellitus susceptibility gene IGF2BP2 is associated with schizophrenia in a Han Chinese population. J. Clin. Psyc., 74: e287-e292.
CrossRef  |  PubMed  |  
72:   Zhang, X., S.L. Guan, Z.Q. Wang, Y. You, S.L. Sun et al., 2012. No association between the type 2 diabetes mellitus susceptibility gene, SLC30A8 and schizophrenia in a Chinese population. Human Psychopharmacol., 27: 392-396.
CrossRef  |  Direct Link  |  
73:   Zhang, X.Y. and J.K. Yao, 2013. Oxidative stress and therapeutic implications in psychiatric disorders. Prog. Neuropsychopharmacol. Biol. Psyc., 46: 197-199.
CrossRef  |  Direct Link  |  
74:   Zhang, X.Y. and T.A. Kosten, 2007. Previous exposure to cocaine enhances cocaine self-administration in an alpha 1-adrenergic receptor dependent manner. Neuropsychopharmacology, 32: 638-645.
75:   Zhang, X.Y. and T.A. Kosten, 2005. Prazosin, an α-1 adrenergic antagonist, reduces cocaine-induced reinstatement of drug-seeking. Biol. Psychiatry, 57: 1202-1204.
CrossRef  |  
76:   Zhang, X.Y., C. Chen da, L.Y. Qi, F. Wang and M.H. Xiu et al., 2009. Gender differences in the prevalence, risk and clinical correlates of tardive dyskinesia in Chinese schizophrenia. Psychopharmacology, 205: 647-654.
CrossRef  |  Direct Link  |  
77:   Zhang, X.Y., C. Chen da, M.H. Xiu, F. Wang and L.Y. Qi et al., 2009. The novel oxidative stress marker thioredoxin is increased in first-episode schizophrenic patients. Schizophrenia Res., 113: 151-157.
CrossRef  |  PubMed  |  
78:   Zhang, X.Y., C. Chen da, M.H. Xiu, F.D. Yang, C.N. Haile, T.A. Kosten and T.R. Kosten, 2012. Gender differences in never-medicated first-episode schizophrenia and medicated chronic schizophrenia patients. J. Clin. Psyc., 73: 1025-1033.
CrossRef  |  PubMed  |  
79:   Zhang, X.Y., C. da Chen, M.H. Xiu, C.N. Haile and X. Luo et al., 2013. Cigarette smoking, psychopathologyand cognitive function in first-episode drug naive schizophrenia: Acase-control study. Psychol. Medic., 43: 1651-1660.
CrossRef  |  PubMed  |  Direct Link  |  
80:   Zhang, X.Y., C.B. Li, M. Li, Y.L. Zheng and C.X. Zhang et al., 2010. Smoking initiation and schizophrenia: A replication study in a Chinese Han population. Schizophrenia Res., 119: 110-114.
CrossRef  |  Direct Link  |  
81:   Zhang, X.Y., C.N. Haile, Y.L. Tan, L.J. Zuo, B.Z. Yang, L.Y. Cao and D.F. Zhou, 2005. Tumour necrosis factor alpha polymorphism (-1031T/C) is associated with age of onset of schizophrenia. Mol. Psychiatry, 10: 897-899.
82:   Zhang, X.Y., D.C. Chen, M.H. Xiu, C.N. Haile and H. Sun et al., 2012. Cigarette smoking and cognitive function in Chinese male schizophrenia: A case-control study. PLoS One, Vol. 7. 10.1371/journal.pone.0036563.
CrossRef  |  
83:   Zhang, X.Y., D.C. Chen, M.H. Xiu, C.N. Haile and H.P. Zhang et al., 2012. Brain-derived neurotrophic factor levels and its Val66Met gene polymorphism predict tardive dyskinesia treatment response to Ginkgo biloba. Biol. Psyc., 72: 700-706.
CrossRef  |  Direct Link  |  
84:   Zhang, X.Y., D.C. Chen, M.H. Xiu, C.N. Haile and H.P. Zhang et al., 2012. Cognitive and serum BDNF correlates of BDNF Val66Met gene polymorphism in patients with schizophrenia and normal controls. Human Gen., 131: 1187-1195.
CrossRef  |  Direct Link  |  
85:   Zhang, X.Y., D.C. Chen, M.H. Xiu, C.N. Haile, T.A. Kosten and T.R. Kosten, 2012. BDNF Val66Met variant and smoking in a Chinese population. PLoS One, Vol. 7. 10.1371/journal.pone.0053295.
CrossRef  |  PubMed  |  
86:   Zhang, X.Y., D.C. Chen, M.H. Xiu, F.D. Yang and Y.L. Tan et al., 2013. Cognitive function, plasma MnSOD activity and MnSOD Ala-9Val polymorphism in patients with schizophrenia and normal controls. Schizophr. Bull. .
PubMed  |  
87:   Zhang, X.Y., D.C. Chen, M.H. Xiu, L. Hui and H. Liu et al., 2012. Association of functional dopamine-beta-hydroxylase (DBH) 19bp insertion/deletion polymorphism with smoking severity in male schizophrenic smokers. Schizophrenia Res., 141: 48-53.
88:   Zhang, X.Y., D.C. Chen, M.H. Xiu, W. Tang and F. Zhang et al., 2012. Plasma total antioxidant status and cognitive impairments in schizophrenia. Schizophrenia Res., 139: 66-72.
CrossRef  |  PubMed  |  
89:   Zhang, X.Y., D.C. Chen, M.H. Xiu, Y.L. Tan and F.D. Yang et al., 2013. Clinical symptoms and cognitive impairment associated with male schizophrenia relate to plasma manganese superoxide dismutase activity: A case-control study. J. Psyc. Res., 47: 1049-1053.
CrossRef  |  Direct Link  |  
90:   Zhang, X.Y., D.C. Chen, Y.L. Tan, M.H. Xiu and J. Cui et al., 2014. Socio-demographic and clinical characteristics of heavy and non-heavy smokers among schizophrenia inpatients in a Chinese Han population. Psychopharmacology, 231: 305-314.
CrossRef  |  PubMed  |  Direct Link  |  
91:   Zhang, X.Y., D.F. Zhou, C.L. Yuan, P.Y. Zhang, G.Y. Wu and Y.C. Shen, 2002. Risperidone-induced increase in serum prolactin is correlated with positive symptom improvement in chronic schizophrenia. Psychiatry Res., 109: 297-302.
PubMed  |  
92:   Zhang, X.Y., D.F. Zhou, G.Y. Wu, L.Y. Cao and Y.L. Tan et al., 2008. BDNF levels and genotype are associated with antipsychotic-induced weight gain in patients with chronic schizophrenia. Neuropsychopharmacology, 33: 2200-2205.
PubMed  |  
93:   Zhang, X.Y., D.F. Zhou, J.M. Su and P.Y. Zhang, 2001. The effect of extract of ginkgo biloba added to haloperidol on superoxide dismutase in inpatients with chronic schizophrenia. J. Clin. Psychopharmacol., 21: 85-88.
PubMed  |  
94:   Zhang, X.Y., D.F. Zhou, L.Y. Cao and G.Y. Wu, 2006. The effects of Ginkgo biloba extract added to haloperidol on peripheral T cell subsets in drug-free schizophrenia: A double-blind, placebo-controlled trial. Psychopharmacology, 188: 12-17.
CrossRef  |  
95:   Zhang, X.Y., D.F. Zhou, L.Y. Cao, C.Q. Xu, D.C. Chen and G.Y. Wu, 2004. The effect of vitamin E treatment on tardive dyskinesia and blood superoxide dismutase: a double-blind placebo-controlled trial. J. Clin. Psychopharmacol., 24: 83-86.
PubMed  |  
96:   Zhang, X.Y., D.F. Zhou, L.Y. Cao, D.C. Chen, F.Y. Zhu and G.Y. Wu, 2003. Blood superoxide dismutase level in schizophrenic patients with tardive dyskinesia: Association with dyskinetic movements. Schizophrenia Res., 62: 245-250.
Direct Link  |  
97:   Zhang, X.Y., D.F. Zhou, L.Y. Cao, G.Y. Wu and Y.C. Shen, 2005. Cortisol and cytokines in chronic and treatment-resistant patients with schizophrenia: Association with psychopathology and response to antipsychotics. Neuropsychopharmacology, 30: 1532-1538.
CrossRef  |  
98:   Zhang, X.Y., D.F. Zhou, L.Y. Cao, G.Y. Wu and Y.C. Shen, 2006. The interaction between superoxide dismutase and prolactin is involved in response to haloperidol and risperidone treatment in schizophrenia: A double-blind and randomized study. J. Clin. Psychopharmacol., 26: 103-105.
PubMed  |  
99:   Zhang, X.Y., D.F. Zhou, L.Y. Cao, P.Y. Zhang and G.Y. Wu, 2002. Decreased production of interleukin-2 (IL-2), IL-2 secreting cells and CD4+ cells in medication-free patients with schizophrenia. J. Psychiatric Res., 36: 331-336.
PubMed  |  
100:   Zhang, X.Y., D.F. Zhou, L.Y. Cao, P.Y. Zhang and G.Y. Wu, 2003. Elevated blood superoxide dismutase in neuroleptic-free schizophrenia: Association with positive symptoms. Psychiatry Res., 117: 85-88.
PubMed  |  
101:   Zhang, X.Y., D.F. Zhou, L.Y. Cao, P.Y. Zhang, G.Y. Wu and Y.C. Shen, 2001. Risperidone versus haloperidol in the treatment of acute exacerbations of chronic inpatients with schizophrenia: A randomized double-blind study. Int. Clin. Psychopharmacol., 16: 325-330.
PubMed  |  
102:   Zhang, X.Y., D.F. Zhou, L.Y. Cao, P.Y. Zhang, G.Y. Wu and Y.C. Shen, 2003. The effect of risperidone treatment on superoxide dismutase in schizophrenia. J. Clin. Psychopharmacol., 23: 128-131.
PubMed  |  Direct Link  |  
103:   Zhang, X.Y., D.F. Zhou, L.Y. Cao, P.Y. Zhang, G.Y. Wu and Y.C. Shen, 2004. Changes in serum interleukin-2, -6 and -8 levels before and during treatment with risperidone and haloperidol: Relationship to outcome in schizophrenia. J. Clin. Psychiat., 65: 940-947.
Direct Link  |  
104:   Zhang, X.Y., D.F. Zhou, L.Y. Cao, P.Y. Zhang, G.Y. Wu and Y.C. Shen, 2005. Prolactin levels in male schizophrenic patients treated with risperidone and haloperidol: A double-blind and randomized study. Psychopharmacology, 178: 35-40.
CrossRef  |  
105:   Zhang, X.Y., D.F. Zhou, L.Y. Qi, S. Chen and L.Y. Cao et al., 2009. Superoxide dismutase and cytokines in chronic patients with schizophrenia: Association with psychopathology and response to antipsychotics. Psychopharmacology, 204: 177-184.
CrossRef  |  Direct Link  |  
106:   Zhang, X.Y., D.F. Zhou, P.Y. Zhang and J. Wei, 2000. The CCK-A receptor gene possibly associated with positive symptoms of schizophrenia. Mol. Psychiatry, 5: 239-240.
PubMed  |  Direct Link  |  
107:   Zhang, X.Y., D.F. Zhou, P.Y. Zhang, G.Y. Wu, J.M. Su and L.Y. Cao, 2001. A double-blind, placebo-controlled trial of extract of Ginkgo biloba added to haloperidol in treatment-resistant patients with schizophrenia. J. Clin. Psychiatry, 62: 878-883.
PubMed  |  
108:   Zhang, X.Y., D.F. Zhou, P.Y. Zhang, G.Y. Wu, L.Y. Cao and Y.C. Shen, 2002. Elevated interleukin-2, interleukin-6 and interleukin-8 serum levels in neuroleptic-free schizophrenia: Association with psychopathology. Schizophr. Res., 57: 247-258.
CrossRef  |  PubMed  |  Direct Link  |  
109:   Zhang, X.Y., D.F. Zhou, Y.C. Shen, P.Y. Zhang, W.F. Zhang et al., 2012. Effects of risperidone and haloperidol on superoxide dismutase and nitric oxide in schizophrenia. Neuropharmacology, 62: 1928-1934.
CrossRef  |  
110:   Zhang, X.Y., F.M. Fan, D.C. Chen, M.H. Xiu and Y.L. Tan et al., 2013. Extensive white matter abnormalities and clinical symptoms in first episode and drug-naive schizophrenia: A voxel-based diffusion tensor imaging study. NeuroImage. .
111:   Zhang, X.Y., H. Sanchez, P. Kehoe and T.A. Kosten, 2005. Neonatal isolation enhances maintenance but not reinstatement of cocaine self-administration in adult male rats. Psychopharmacology, 177: 391-399.
CrossRef  |  
112:   Zhang, X.Y., J. Liang, D.C. Chen, M.H. Xiu and J. He et al., 2012. Cigarette smoking in male patients with chronic schizophrenia in a Chinese population: Prevalence and relationship to clinical phenotypes. PLoS One, Vol. 7. 10.1371/journal.pone.0030937.
CrossRef  |  
113:   Zhang, X.Y., J. Liang, D.C. Chen, M.H. Xiu, F. De Yang, T.A. Kosten and T.R. Kosten, 2012. Low BDNF is associated with cognitive impairment in chronic patients with schizophrenia. Psychopharmacology, 222: 277-284.
CrossRef  |  Direct Link  |  
114:   Zhang, X.Y., L. Liu, S. Liu, X. Hong and D.C. Chen et al., 2012. Short-term tropisetron treatment improves deficits in auditory P50 suppression in schizophrenia: Dose-response relationship. Am. J. Psyc., 169: 974-981.
115:   Zhang, X.Y., L.Y. Cao, C. Song, G.Y. Wu and C. Chen et al., 2008. Lower serum cytokine levels in smokers than nonsmokers with chronic schizophrenia on long-term treatment with antipsychotics. Psychopharmacology, 201: 383-389.
CrossRef  |  Direct Link  |  
116:   Zhang, X.Y., M.H. Xiu, C. Song, D.C. Chen and G.Y. Wu et al., 2010. Increased serum S100B in never-medicated and medicated schizophrenic patients. J. Psychiatric Res., 44: 1236-1240.
CrossRef  |  Direct Link  |  
117:   Zhang, X.Y., M.H. Xiu, D.C. Chen, F. de Yang and G.Y. Wu et al., 2010. Nicotine dependence and serum BDNF levels in male patients with schizophrenia. Psychopharmacology, 212: 301-307.
CrossRef  |  
118:   Zhang, X.Y., M.H. Xiu, D.C. Chen, F.Y. Zhu and G.Y. Wu et al., 2010. Increased S100B serum levels in schizophrenic patients with tardive dyskinesia: Association with dyskinetic movements. J. Psychiatric Res., 44: 429-433.
CrossRef  |  Direct Link  |  
119:   Zhang, X.Y., P. Kehoe and T.A. Kosten, 2006. Neonatal isolation alters estrous cycle effects on ventral striatal extracellular monoamine levels. Progress Neuro-Psychopharmacol. Biol. Psychiatry, 30: 504-511.
CrossRef  |  
120:   Zhang, X.Y., R.K. Al-Jurdi, A.W. Zoghbi, C. da Chen and M.H. Xiu et al., 2013. Prevalence, demographic and clinical correlates of suicide attempts in Chinese medicated chronic inpatients with schizophrenia. J. Psychiatr. Res., 47: 1370-1375.
CrossRef  |  PubMed  |  Direct Link  |  
121:   Zhang, X.Y., R.L. Zhang, M. Pan, D.C. Chen, M.H. Xiu and T.R. Kosten, 2010. Sex difference in the prevalence of smoking in Chinese schizophrenia. J. Psychiatric Res., 44: 986-988.
CrossRef  |  Direct Link  |  
122:   Zhang, X.Y., W. Tang, M.H. Xiu, C. da Chun and F.D. Yang et al., 2013. Interleukin 18 and cognitive impairment in first episode and drug naive schizophrenia versus healthy controls. Brain Behav. Immun., 32: 105-111.
CrossRef  |  PubMed  |  Direct Link  |  
123:   Zhang, X.Y., Y.L. Tan, D.F. Zhou, C.N. Haile and L.Y. Cao et al., 2007. Association of clozapine-induced weight gain with a polymorphism in the leptin promoter region in patients with chronic schizophrenia in a Chinese population. J. Clin. Psychopharmacol., 27: 246-251.
124:   Zhang, X.Y., Y.L. Tan, D.F. Zhou, C.N. Haile, G.Y. Wu et al., 2007. Nicotine dependence, symptoms and oxidative stress in male patients with schizophrenia. Neuropsychopharmacology, 32: 2020-2024.
PubMed  |  
125:   Zhang, X.Y., Y.L. Tan, D.F. Zhou, L.Y. Cao and G.Y. Wu et al., 2007. Disrupted antioxidant enzyme activity and elevated lipid peroxidation products in schizophrenic patients with tardive dyskinesia. J. Clin. Psychiatry, 68: 754-760.
PubMed  |  
126:   Zhang, X.Y., Y.L. Tan, D.F. Zhou, L.Y. Cao and G.Y. Wu et al., 2007. Serum BDNF levels and weight gain in schizophrenic patients on long-term treatment with antipsychotics. J. Psychiatr. Res., 41: 997-1004.
CrossRef  |  PubMed  |  Direct Link  |  
127:   Zhang, X.Y., Y.L. Tan, L.Y. Cao, G.Y. Wu, Q. Xu, Y. Shen and D.F. Zhou, 2006. Antioxidant enzymes and lipid peroxidation in different forms of schizophrenia treated with typical and atypical antipsychotics. Schizophrenia Res., 81: 291-300.
CrossRef  |  
128:   Zhang, X.Y., Y.Q. Yu, S. Sun, X. Zhang and W. Li et al., 2011. Smoking and tardive dyskinesia in male patients with chronic schizophrenia. Prog. Neuropsychopharmacol. Biol. Psychiatry, 35: 1765-1769.
CrossRef  |  PubMed  |  
129:   Zhao, L.Y., J. Shi, X.L. Zhang, D.H. Epstein and X.Y. Zhang et al., 2010. Stress enhances retrieval of drug-related memories in abstinent heroin addicts. Neuropsychopharmacology, 35: 720-726.
CrossRef  |  
130:   Zhen, Y.F., J. Zhang, X.Y. Liu, H. Fang and L.B. Tian et al., 2013. Low BDNF is associated with cognitive deficits in patients with type 2 diabetes. Psychopharmacology, 227: 93-100.
CrossRef  |  
131:   Zhou, D., X.Y. Zhang, J. Su, Z. Nan and Y. Cui et al., 1999. The effects of classic antipsychotic haloperidol plus the extract of ginkgo biloba on superoxide dismutase in patients with chronic refractory schizophrenia. Chinese Med. J., 112: 1093-1096.
PubMed  |  Direct Link  |  
132:   Zhou, D.H., Q.Z. Yan, X.M. Yan, C.B. Li and H. Fang et al., 2010. The study of BDNF Val66Met polymorphism in Chinese schizophrenic patients. Prog. Neuropsychopharmacol. Biol. Psychiatry, 34: 930-933.
CrossRef  |  PubMed  |  
133:   Zhou, N., Q. Yu, X. Li, Y. Yu and C. Kou et al., 2013. Association of the dopamine β-hydroxylase 19 bp insertion/deletion polymorphism with positive symptoms but not tardive dyskinesia in schizophrenia. Hum. Psychopharmacol. Clin. Exp., 28: 230-237.
CrossRef  |  PubMed  |  Direct Link  |  
134:   Zuo, L, F. Wang, C.S. Li, L. Lu and Y. Fu et al., 2013. Genome-wide significant association signals in IPO11-HTR1A region specific for alcohol and nicotine co-dependence. Alcoholism. Clin. Exp. Res., 37: 730-739.
CrossRef  |  Direct Link  |  
135:   Zuo, L., C.K. Zhang, F. Wang, C.S. Li and H. Zhao et al., 2011. A novel, functional and replicable risk gene region for alcohol dependence identified by genome-wide association study. PLoS One, Vol. 6. 10.1371/journal.pone.0026726.
CrossRef  |  
136:   Zuo, L., F. Zhang, H. Zhang, X.Y. Zhang and F. Wang et al., 2012. Genome-wide search for replicable risk gene regions in alcohol and nicotine co-dependence. Am. J. Med. Genet. Part B: Neuropsychiatr. Genet., 159B: 437-444.
CrossRef  |  
137:   Zuo, L., H. Zhang, R.T. Malison, C.S. Li and X.Y. Zhang et al., 2013. Rare ADH variant constellations are specific for alcohol dependence. Alcohol. Alcoholism., 48: 9-14.
CrossRef  |  PubMed  |  
138:   Zuo, L., J. Gelernter, C.K. Zhang, H. Zhao and L. Lu et al., 2012. Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q. Neuropsychopharmacology, 37: 557-566.
CrossRef  |  PubMed  |  
139:   Zuo, L., K. Wang, X.Y. Zhang, J.H. Krystal and C.S. Li et al., 2013. NKAIN1-SERINC2 is a functional, replicable and genome-wide significant risk gene region specific for alcohol dependence in subjects of European descent. Drug Alcohol Depend., 129: 254-264.
CrossRef  |  PubMed  |  Direct Link  |  
140:   Zuo, L., K. Wang, X.Y. Zhang, X. Pan and G. Wang et al., 2013. Association between common alcohol dehydrogenase gene (ADH) variants and schizophrenia and autism. Hum. Genet., 132: 735-743.
CrossRef  |  PubMed  |  Direct Link  |  
141:   Zuo, L., K. Wang, X.Y. Zhang, X. Pan and G. Wang et al., 2013. Sex chromosome-wide association analysis suggested male-specific risk genes for alcohol dependence. Psychiatr. Genet., 23: 233-238.
CrossRef  |  PubMed  |  
142:   Zuo, L., K.S. Wang, X.Y. Zhang, C.S. Li and F. Zhang et al., 2013. Rare SERINC2 variants are specific for alcohol dependence in individuals of European descent. Pharmacogenet. Genomics, 23: 395-402.
CrossRef  |  PubMed  |  
143:   Zuo, L., L. Saba, K. Wang, X.Y. Zhang, J.H. Krystal, B. Tabakoff and X. Luo, 2013. Exome-wide association study of replicable nonsynonymous variants conferring risk for alcohol dependence. J. Stud. Alcohol, 74: 622-625.
PubMed  |  
144:   Zuo, L., X.Y. Zhang, H.W. Deng and X. Luo, 2013. Association of rare PTP4A1-PHF3-EYS variants with alcohol dependence. J. Human Genetics, 58: 178-179.