Hi, I am Hsueh-Wei Chang, My LiveDNA is 886.5928
 
   
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Dr. Hsueh-Wei Chang
 
Highest Degree: Ph.D. in Bioinformatics from National Tsing Hua University, Taiwan
 
Institute: Kaohsiung Medical University, Taiwan
 
Area of Interest: Biomedical Sciences
  •   Bioinformatics
  •   Genomics
  •   Genetic Diversity
  •   Natural Products
 
URL: http://livedna.org/886.5928
 
My SELECTED Publications
1:   Chang, H.W. and I.M. Shih, 2005. Digital Single-Nucleotide Polymorphism analysis for Allelic Imbalance. In: Pancreatic Cancer: Methods and Protocols, Su, G.H. (Ed.). Springer, USA., pp: 137-141.
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2:   Chang, H.W., C.A. Cheng, D.L. Gu, C.C. Chang and S.H. Su et al., 2008. High-throughput avian molecular sexing by SYBR green-based real-time PCR combined with melting curve analysis. BMC Biotechnol., Vol. 8. 10.1186/1472-6750-8-12.
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3:   Chang, H.W., C.H. Yang, C.H. Ho, C.H. Wen and L.Y. Chuang, 2009. Generating SNP barcode to evaluate SNP-SNP interaction of disease by particle swarm optimization. Comput. Biol. Chem., 33: 114-119.
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4:   Chang, H.W., C.H. Yang, P.L. Chang, Y.H. Cheng and L.Y. Chuang, 2006. SNP-RFLPing: Restriction enzyme mining for SNPs in genomes. BMC Genom., Vol. 7. 10.1186/1471-2164-7-30.
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5:   Chang, H.W., C.Y. Yen, S.Y. Liu, G. Singer and I.M. Shih, 2002. Genotype analysis using human hair shaft. Cancer Epidemiol. Biomarkers Prev., 11: 925-929.
PubMed  |  Direct Link  |  
6:   Chang, H.W., D.L. Gu, S.H. Su, C.C. Chang and C.A. Cheng et al., 2008. High-throughput gender identification of Accipitridae eagles with real-time PCR using TaqMan probes. Theriogenology, 70: 83-90.
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7:   Chang, H.W., J.I. Yang, H.Y. Huang, J.C. Gwo, Y.F. Su, C.H. Wen and Y.C. Chou, 2009. A novel growth hormone 1 gene-derived probe for Oncorhynchus masou formosanus distinguished from the Oncorhynchus subspecies. Mol. Cell. Probes, 23: 103-106.
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8:   Chang, H.W., K.H. Tsui, L.C. Shen, H.W. Huang, S.N. Wang and P.L. Chang, 2007. Urinary cell-free DNA as a potential tumor marker for bladder cancer. Int. J. Biol. Markers, 22: 287-294.
PubMed  |  
9:   Chang, H.W., L.Y. Chuan, Y.H. Cheng, Y.C. Hung, C.H. Wen, D.L. Gu and C.H. Yang, 2009. Prim-SNPing: A primer designer for cost-effective SNP genotyping. Biotechniques, 46: 421-431.
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10:   Chang, H.W., L.Y. Chuang, C.H. Ho, P.L. Chang and C.H. Yang, 2008. Odds ratio-based genetic algorithms for generating SNP barcodes of genotypes to predict disease susceptibility. OMICS J. Integr. Biol., 12: 71-81.
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11:   Chang, H.W., L.Y. Chuang, M.T. Tsai and C.H. Yang, 2012. The importance of integrating SNP and cheminformatics resources to pharmacogenomics. Curr. Drug Metab., 13: 991-999.
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12:   Chang, H.W., L.Y. Chuang, S. Guleria and S. Yasmin, 2013. Natural products: Bioactivity, biochemistry, and biological effects in cancer and disease therapy. Sci. World J., 10.1155/2013/713480.
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13:   Chang, H.W., L.Y. Chuang, Y.H. Cheng, C.H. Ho, C.H. Wen and C.H. Yang, 2009. Seq-SNPing: Multiple-alignment tool for SNP discovery, SNP ID identification, and RFLP genotyping. OMICS: J. Integr. Biol., 13: 253-260.
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14:   Chang, H.W., L.Y. Chuang, Y.H. Cheng, D.L. Gu, H.W. Huang and C.H. Yang, 2010. An Introduction to Mitochondrial Informatics. In: Genetic Variation: Methods in Molecular Biology, Barnes, M.R. and G. Breen (Eds.). Humana Press, Totowa, NJ, USA., pp: 259-274.
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15:   Chang, H.W., L.Y. Chuang, Y.J. Chang, Y.H. Cheng and Y.C. Hung et al., 2009. LD2SNPing: Linkage disequilibrium plotter and RFLP enzyme mining for tag SNPs. BMC Genet., Vol. 10. 10.1186/1471-2156-10-26.
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16:   Chang, H.W., S. Ali, R.J. Kurman and I.M. Shih, 2002. Detection of allelic imbalance in ascites fluids correlates with cancer status. Clin. Cancer Res., 8: 2580-2585.
17:   Chang, H.W., S.M. Lee, S.N. Goodman, G. Singer and S.K. Cho et al., 2002. Assessment of plasma DNA levels, allelic imbalance, and CA 125 as diagnostic tests for cancer. J. Nat. Cancer Inst., 94: 1697-1703.
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18:   Chang, H.W., T.C. Chou, D.L. Gu, C.A. Cheng and C.C. Chang et al., 2008. An improved PCR method for gender identification of eagles. Mol. Cell. Probes, 22: 184-188.
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19:   Chang, H.W., Y.C. Chou, Y.F. Su, C.A. Cheng and C.T. Yao et al., 2010. Molecular phylogeny of the Pycnonotus sinensis and Pycnonotus taivanus in Taiwan based on sequence variations of nuclear CHD and mitochondrial cytochrome b genes. Biochem. Syst. Ecol., 38: 195-201.
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20:   Chang, H.W., Y.C. Lai, C.Y. Cheng, J.L. Ho, S.T. Ding and Y.C. Liu, 1999. UV inducibility of rat proliferating cell nuclear antigen gene promoter. J. Cell. Biochem., 73: 423-432.
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21:   Chang, H.W., Y.H. Cheng, L.Y. Chuang and C.H. Yang, 2010. SNP-RFLPing 2: An updated and integrated PCR-RFLP tool for SNP genotyping. BMC Bioinformat., Vol. 11. 10.1186/1471-2105-11-173.
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22:   Chang, H.W., Y.H. Chiu, H.Y. Kao, C.H. Yang and W.H. Ho, 2013. Comparison of classification algorithms with wrapper-based feature selection for predicting osteoporosis outcome based on genetic factors in a Taiwanese women population. Int. J. Endocrinol., 10.1155/2013/850735.
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23:   Chang, Y.C., H.W. Chang, C.B. Liao and Y.C. Liu, 2002. The roles of p53, DNA repair, and oxidative stress in ultraviolet C induction of proliferating cell nuclear antigen expression. Ann. N. Y. Acad. Sci., 973: 384-391.
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24:   Chang, Y.F., H.J. Chou, Y.C. Yen, H.W. Chang, Y.R. Hong, H.W. Huang and C.N. Tseng, 2012. Agrin induces association of Chrna1 mRNA and nicotinic acetylcholine receptor in C2C12 myotubes. FEBS Lett., 586: 3111-3116.
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25:   Chen, B.H., H.W. Chang, H.M. Huang, I.W. Chong, J.S. Chen, C.Y. Chen and H.M. Wang, 2011. (-)-Anonaine induces DNA damage and inhibits growth and migration of human lung carcinoma H1299 cells. J. Agric. Food Chem., 59: 2284-2290.
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26:   Chen, B.H., M.H. Hung, J.Y.F. Chen, H.W. Chang and M.L. Yu et al., 2012. Anti-allergic activity of grapeseed extract (GSE) on RBL-2H3 mast cells. Food Chem., 132: 968-974.
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27:   Chen, C.C., H.T. Chiu, Y.T. Chang, Y.C. Chou and J. Lin et al., 2012. An improved methodology for gender identification of Pygoscelis papua. Theriogenol. Insight Int. J. Reprod. Animals, 2: 99-108.
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28:   Chen, C.C., Y.S. Liu, C.C. Cheng, C.L. Wang, M.H. Liao, C.N. Tseng and H.W. Chang, 2012. High-throughput sex identification by melting curve analysis in blue-breasted quail and chicken. Theriogenology, 77: 1951-1958.
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29:   Chen, C.Y., P.Y. Wu, T.S. Huang, C.W. Lin and Y.C. Li et al., 2009. The sour taste-modifying protein (miraculin), tyrosinase inhibitors and antioxidants from Synsepalum dulcificum. Curr. Nutr. Food Sci., 5: 172-179.
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30:   Chen, F.M., H.W. Chang, S.F. Yang, Y.F. Huang, P.Y. Nien, Y.T. Yeh and M.F. Hou, 2012. The mitogen-activated protein kinase phosphatase-1 (MKP-1) gene is a potential methylation biomarker for malignancy of breast cancer. Exp. Mol. Med., 44: 356-362.
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31:   Chen, J.B., L.Y. Chuang, Y.D. Lin, C.W. Liou and T.K. Lin et al., 2013. Genetic algorithm-generated SNP barcodes of the mitochondrial D-loop for chronic dialysis susceptibility. Mitochondrial DNA, 10.3109/19401736.2013.796513.
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32:   Chen, J.B., L.Y. Chuang, Y.D. Lin, C.W. Liou and T.K. Lin et al., 2013. Preventive SNP-SNP interactions in the mitochondrial displacement loop (D-loop) from chronic dialysis patients. Mitochondrion, 13: 698-704.
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33:   Chen, J.B., Y.H. Yang, W.C. Lee, C.W. Liou and T.K. Lin et al., 2012. Sequence-based polymorphisms in the mitochondrial D-loop and potential SNP predictors for chronic dialysis. PloS One, Vol. 7. 10.1371/journal.pone.0041125.
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34:   Chen, J.Y.F., C.C. Hwang, W.Y. Chen, J.C. Lee and T.F. Fu et al., 2010. Additive effects of C 2-ceramide on paclitaxel-induced premature senescence of human lung cancer cells. Life Sci., 87: 350-357.
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35:   Chen, K.J., C.K. Tseng, F.R. Chang, J.I. Yang and C.C. Yeh et al., 2013. Aqueous extract of the edible Gracilaria tenuistipitata inhibits hepatitis C viral replication via cyclooxygenase-2 suppression and reduces virus-induced inflammation. PloS One, Vol. 8. 10.1371/journal.pone.0057704.
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36:   Cheng, Y.H., C.S. Yang, H.W. Chang, L.Y. Chuang and C.H. Yang, 2007. A novel method providing exact SNP IDs from sequences. IAENG Int. J. Comput. Sci., Vol. 34. .
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37:   Chiu, C.C., H.W. Chang, D.W. Chuang, F.R. Chang and Y.C. Chang et al., 2009. Fern plant-derived protoapigenone leads to DNA damage, apoptosis, and G2/M arrest in lung cancer cell line H1299. DNA Cell Biol., 28: 501-506.
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38:   Chiu, C.C., J.W. Haung, F.R. Chang, K.J. Huang and H.M. Huang et al., 2013. Golden berry-derived 4β-hydroxywithanolide E for selectively killing oral cancer cells by generating ROS, DNA damage, and apoptotic pathways. PloS One, Vol. 8. 10.1371/journal.pone.0064739.
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39:   Chiu, C.C., P.L. Liu, K.J. Huang, H.M. Wang and K.F. Chang et al., 2011. Goniothalamin inhibits growth of human lung cancer cells through DNA damage, apoptosis, and reduced migration ability. J. Agric. Food Chem., 59: 4288-4293.
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40:   Chou, T.C., C.T. Yao, S.H. Su, Y.C. Hung and W.S. Chen et al., 2010. Validation of Spilornis cheela hoya TaqMan probes for potential gender identification of many Accipitridae species. Theriogenology, 73: 404-411.
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41:   Chuang, L.Y., C.H. Ke, H.W. Chang and C.H. Yang, 2009. A two-stage feature selection method for gene expression data. OMICS: J. Integr. Biol., 13: 127-137.
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42:   Chuang, L.Y., C.H. Yang, K.H. Tsui, Y.H. Cheng, P.L. Chang, C.H. Wen and H.W. Chang, 2008. Restriction enzyme mining for SNPs in genomes. Anticancer Res., 28: 2001-2007.
PubMed  |  Direct Link  |  
43:   Chuang, L.Y., C.H. Yang, Y.H. Cheng and H.W. Chang, 2007. A mixed method for providing exact SNP IDs from sequences. Biomed. Eng.: Appl. Basis Commun., 19: 251-257.
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44:   Chuang, L.Y., C.H. Yang, Y.H. Cheng, D.L. Gu, P.L. Chang, K.H. Tsui and H.W. Chang, 2006. V-MitoSNP: Visualization of human mitochondrial SNPs. BMC Bioinformat., Vol. 7. 10.1186/1471-2105-7-379.
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45:   Chuang, L.Y., H.W. Chang, C.J. Tu and C.H. Yang, 2008. Improved binary PSO for feature selection using gene expression data. Comput. Biol. Chem., 32: 29-38.
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46:   Chuang, L.Y., H.W. Chang, J.H. Tsai and C.H. Yang, 2012. Features for computational operon prediction in prokaryotes. Briefings Functional Genom., 11: 291-299.
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47:   Chuang, L.Y., H.W. Chang, M.C. Lin and C.H. Yang, 2012. Chaotic particle swarm optimization for detecting SNP-SNP interactions for CXCL12-related genes in breast cancer prevention. Eur. J. Cancer Prev., 21: 336-342.
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48:   Chuang, L.Y., H.W. Chang, M.C. Lin and C.H. Yang, 2013. Improved branch and bound algorithm for detecting SNP-SNP interactions in breast cancer. J. Clin. Bioinformat., Vol. 3. 10.1186/2043-9113-3-4.
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49:   Chuang, L.Y., M.C. Lin, H.W. Chang and C.H. Yang, 2012. Chaotic particle swarm optimization for prediction of SNP combinations associated with a low bone mineral density risk. Proceedings of the International Multi Conference of Engineers and Computer Scientists, Volume 1, March 14-16, 2012, Hong Kong, pp: 111-116.
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50:   Chuang, L.Y., Y.D. Lin, H.W. Chang and C.H. Yang, 2012. An improved PSO algorithm for generating protective SNP barcodes in breast cancer. PloS One, Vol. 7. 10.1371/journal.pone.0037018.
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51:   Hseu, Y.C., C.R. Wu, H.W. Chang, K.J.S. Kumar and M.K. Lin et al., 2011. Inhibitory effects of Physalis angulata on tumor metastasis and angiogenesis. J. Ethnopharmacol., 135: 762-771.
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52:   Hseu, Y.C., H.T. Tsou, K.J. Senthil Kumar, K.Y. Lin, H.W. Chang and H.L. Yang, 2012. The antitumor activity of Antrodia camphorata in melanoma cells: Modulation of Wnt/β-catenin signaling pathways. Evidence Based Compl. Altern. Med., 10.1155/2012/197309.
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53:   Huang, H.W., Y.F. Su, C.T. Yao, Y.C. Hung and C.C. Chen et al., 2011. High-throughput gender identification of three Columbidae species using melting curve analysis. Theriogenology, 75: 73-79.
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54:   Huang, W.H., C.N. Tseng, J.Y. Tang, C.H. Yang, S.S. Liang and H.W. Chang, 2013. RNA editing and drug discovery for cancer therapy. Sci. World J., 10.1155/2013/804505.
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55:   Lee, H.E., C.Y. Li, H.W. Chang, Y.H. Yang and J.H. Wu, 2011. Effects of different denture cleaning methods to remove Candida albicans from acrylic resin denture based material. J. Dental Sci., 6: 216-220.
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56:   Lee, J.C., M.F. Hou and H.W. Huang, F.R. Chang, C.C. Yeh, J.Y. Tang and H.W. Chang, 2013. Marine algal natural products with anti-oxidative, anti-inflammatory, and anti-cancer properties. Cancer Cell Int., Vol. 13. 10.1186/1475-2867-13-55.
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57:   Liang, M.T., C.H. Yang, S.T. Li, C.S. Yang and H.W. Chang et al., 2008. Antibacterial and antioxidant properties of Ramulus cinnamomi using supercritical CO2 extraction. Eur. Food Res. Technol., 227: 1387-1396.
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58:   Lin, C.T., H.W. Chang, G.S. Chen, C.L. Lin and D.L. Gu, 2007. Herpes simplex mimicking herpes zoster in a 3-year-old child-a case report. Dermatologica Sinica, 25: 194-199.
59:   Lin, C.W., P.F. Tu, N.W. Hsiao, C.Y. Chang, L. Wan, Y.T. Lin and H.W. Chang, 2007. Identification of a novel septin 4 protein binding to human herpesvirus 8 kaposin a protein using a phage display cDNA library. J. Virol. Methods, 143: 65-72.
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60:   Lin, E., W.H. Lin, S.Y. Wang, C.S. Chen and J.W. Liao et al., 2012. Flavokawain B inhibits growth of human squamous carcinoma cells: Involvement of apoptosis and cell cycle dysregulation in vitro and in vivo. J. Nutr. Biochem., 23: 368-378.
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61:   Lin, G.T., H.F. Tseng, C.H. Yang, M.F. Hou and L.Y. Chuang et al., 2009. Combinational polymorphisms of seven CXCL12-related genes are protective against breast cancer in Taiwan. OMICS: J. Integr. Biol., 13: 165-172.
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62:   Lin, G.T., H.F. Tseng, C.K. Chang, L.Y. Chuang and C.S. Liu et al., 2008. SNP combinations in chromosome-wide genes are associated with bone mineral density in Taiwanese women. Chinese J. Physiol., 51: 32-41.
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63:   Lin, G.T., H.W. Chang, C.S. Liu, P.J. Huang, H.C. Wang and Y.M. Cheng, 2006. De novo 617G-A nucleotide mutation in the ACVR1 gene in a Taiwanese patient with fibrodysplasia ossificans progressiva. J. Human Genet., 51: 1083-1086.
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64:   Lin, S.D., S.H. Huang, Y.N. Lin, S.H. Wu and H.W. Chang et al., 2011. Engineering adipose tissue from uncultured human adipose stromal vascular fraction on collagen matrix and gelatin sponge scaffolds. Tissue Eng. A, 17: 1489-1498.
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65:   Lin, T.M., H.W. Chang, K.H. Wang, A.P. Kao and C.C. Chang et al., 2007. Isolation and identification of mesenchymal stem cells from human lipoma tissue. Biochem. Biophys. Res. Commun., 361: 883-889.
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66:   Liu, C.S., T.M. Cham, C.H. Yang, H.W. Chang, C.H. Chen and L.Y. Chuang, 2007. Antibacterial properties of Chinese herbal medicines against nosocomial antibiotic resistant strains of Pseudomonas aeruginosa in Taiwan. Am. J. Chin. Med., 35: 1047-1060.
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67:   Liu, Y.C., H.W. Chang, Y.C. Lai, S.T. Ding and J.L. Ho, 1998. Serum responsiveness of the rat PCNA promoter involves the proximal ATF and AP-1 sites. FEBS Lett., 441: 200-204.
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68:   Salani, R., I. Neuberger, R.J. Kurman, R.E. Bristow, H.W. Chang, T.L. Wang and I.M. Shih, 2007. Expression of extracellular matrix proteins in ovarian serous tumors. Int. J. Gynecol. Pathol., 26: 141-146.
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69:   Singer, G., R.J. Kurman, H.W. Chang, S.K. Cho and I.M. Shih, 2002. Diverse tumorigenic pathways in ovarian serous carcinoma. Am. J. Pathol., 160: 1223-1228.
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70:   Stocker, J., H.W. Huang, H.M. Wang, H.W. Chang and C.C. Chiu, C.L. Cho and C.N. Tseng, 2013. Reduction of RNA A-to-I editing in Drosophila acclimated to heat shock. Kaohsiung J. Med. Sci., 29: 478-483.
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71:   Tan, H.F., C.Y. Yeh, H.W. Chang, C.K. Chang and H.F. Tseng, 2009. Private doctors' practices, knowledge, and attitude to reporting of communicable diseases: A national survey in Taiwan. BMC Infect. Dis., Vol. 9. 10.1186/1471-2334-9-11.
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72:   Tang, J.Y., H.W. Chang and J.G. Chang, 2013. Modulating roles of amiloride in irradiation-induced antiproliferative effects in glioblastoma multiforme cells involving akt phosphorylation and the alternative splicing of apoptotic genes. DNA Cell Biol., 32: 504-510.
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73:   Tang, J.Y., J.C. Lee, M.F. Hou, C.L. Wang, C.C. Chen, H.W. Huang and H.W. Chang, 2013. Alternative splicing for diseases, cancers, drugs, and databases. Sci. World J., 10.1155/2013/703568.
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74:   Tang, J.Y., J.C. Lee, Y.T. Chang, M.F. Hou, C.C. Liaw and H.W. Chang, 2013. Long noncoding RNAs-related diseases, cancers, and drugs. Sci. World J., 10.1155/2013/943539.
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75:   Tang, J.Y., L.Y. Chuang, E. Hsi, Y.D. Lin, C.H. Yang and H.W. Chang, 2013. Identifying the association rules between clinicopathologic factors and higher survival performance in operation-centric oral cancer patients using the apriori algorithm. BioMed Res. Int., 10.1155/2013/359634.
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76:   Tseng, C.N., C.F. Huang, C.L. Cho, H.W. Chang and C.W. Huang et al., 2013. Brefeldin a effectively inhibits cancer stem cell-like properties and mmp-9 activity in human colorectal cancer colo 205 cells. Molecules, 18: 10242-10253.
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77:   Tseng, C.N., H.W. Chang, J. Stocker, H.C. Wang and C.C. Lu et al., 2013. A method to identify RNA A-to-I editing targets using I-specific cleavage and exon array analysis. Mol. Cell. Probes, 27: 38-45.
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78:   Tseng, H.F., C.K. Chang, H.F. Tan, S.E. Yang and H.W. Chang, 2006. Seroepidemiology study of rubella antibodies among pregnant women from seven Asian countries: Evaluation of the rubella vaccination program in Taiwan. Vaccine, 24: 5772-5777.
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79:   Tzang, B.S., Y.C. Lai, M. Hsu, H.W. Chang, C.C. Chang, P.C. Huang and Y.C. Liu, 1999. Function and sequence analyses of tumor suppressor gene p53 of CHO.K1 cells. DNA Cell Biol., 18: 315-321.
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80:   Wang, H.M., J.L. Pan, C.Y. Chen, C.C. Chiu, M.H. Yang, H.W. Chang and J.S. Chang, 2010. Identification of anti-lung cancer extract from Chlorella vulgaris C-C by antioxidant property using supercritical carbon dioxide extraction. Process Biochem., 45: 1865-1872.
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81:   Wang, H.M., K.C. Cheng, C.J. Lin, S.W. Hsu and W.C. Fang et al., 2010. Obtusilactone A and (-)-sesamin induce apoptosis in human lung cancer cells by inhibiting mitochondrial Lon protease and activating DNA damage checkpoints. Cancer Sci., 101: 2612-2620.
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82:   Wei, J.C.C., J.H. Yen, S.H.H. Juo, W.C. Chen and Y.S. Wang et al., 2011. Association of ORAI1 haplotypes with the risk of HLA-B27 positive ankylosing spondylitis. PloS One, Vol. 6. 10.1371/journal.pone.0020426.
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83:   Wu, S.J., L.Y. Chuang, Y.D. Lin, W.H. Ho, F.T. Chiang, C.H. Yang and H.W. Chang, 2013. Particle swarm optimization algorithm for analyzing SNP-SNP interaction of renin-angiotensin system genes against hypertension. Mol. Biol. Rep., 40: 4227-4233.
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84:   Yang, C., Y. Lin, L. Chaung and H. Chang, 2013. Evaluation of breast cancer susceptibility using improved genetic algorithms to generate genotype SNP barcodes. IEEE/ACM Trans. Comput. Biol. Bioinformat., 10: 361-371.
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85:   Yang, C.H., H.W. Chang, C.H. Ho, Y.C. Chou and L.Y. Chuang, 2011. Conserved PCR primer set designing for closely-related species to complete mitochondrial genome sequencing using a sliding window-based PSO algorithm. PLoS One, Vol. 6. 10.1371/journal.pone.0017729.
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86:   Yang, C.H., H.W. Chang, H.Y. Lin and L.Y. Chuang, 2013. Evaluation of antioxidant and antimicrobial activities from 28 Chinese herbal medicines. J. Pharm. Phytochem., 2: 294-305.
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87:   Yang, C.H., H.W. Chang, Y.H. Cheng and L.Y. Chuang, 2009. Novel generating protective single nucleotide polymorphism barcode for breast cancer using particle swarm optimization. Cancer Epidemiol., 33: 147-154.
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88:   Yang, C.H., L.Y. Chuang, T.M. Shih and H.W. Chang, 2010. hSAGEing: An improved SAGE-based software for identification of human tissue-specific or common tumor markers and suppressors. PloS One, Vol. 5. 10.1371/journal.pone.0014369.
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89:   Yang, C.H., L.Y. Chuang, Y.H. Cheng, C.H. Wen and H.W. Chang, 2009. Dynamic programming for single nucleotide polymorphism ID identification in systematic association studies. Kaohsiung J. Med. Sci., 25: 165-176.
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90:   Yang, C.H., L.Y. Chuang, Y.H. Cheng, C.H. Wen, P.L. Chang and H.W. Chang, 2008. SNP ID-info: SNP ID searching and visualization platform. OMICS: J. Integr. Biol., 12: 217-226.
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91:   Yang, C.H., L.Y. Chuang, Y.H. Cheng, D.L. Gu, C.H. Chen and H.W. Chang, 2010. Methyl-Typing: An improved and visualized COBRA software for epigenomic studies. FEBS Lett., 584: 739-744.
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92:   Yang, C.H., L.Y. Chuang, Y.H. Cheng, Y.D. Lin, C.L. Wang, C.H. Wen and H.W. Chang, 2012. Single nucleotide polymorphism barcoding to evaluate oral cancer risk using odds ratio-based genetic algorithms. Kaohsiung J. Med. Sci., 28: 362-368.
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93:   Yang, C.H., L.Y. Chuang, Y.J. Chen, H.F. Tseng and H.W. Chang, 2011. Computational analysis of simulated SNP interactions between 26 growth factor-related genes in a breast cancer association study. Omics: J. Integr. Biol., 15: 399-407.
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94:   Yang, C.H., T.M. Shih, Y.C. Hung, H.W. Chang and L.Y. Chuang, 2009. Extract-SAGE: An integrated platform for cross-analysis and GA-based selection of SAGE data. Bioinformation, 3: 291-292.
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95:   Yang, C.H., Y.D. Lin, L.Y. Chuang, J.B. Chen and H.W. Chang, 2013. MDR-ER: Balancing functions for adjusting the ratio in risk classes and classification errors for imbalanced cases and controls using multifactor-dimensionality reduction. PloS One, Vol. 8. 10.1371/journal.pone.0079387.
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96:   Yang, C.H., Y.H. Cheng, L.Y. Chuang and H.W. Chang, 2008. SNP-Flankplus: SNP ID-centric retrieval for SNP flanking sequences. Bioinformation, 3: 147-149.
PubMed  |  
97:   Yang, C.H., Y.H. Cheng, L.Y. Chuang and H.W. Chang, 2009. Specific PCR product primer design using memetic algorithm. Biotechnol. Progr., 25: 745-753.
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98:   Yang, C.H., Y.H. Cheng, L.Y. Chuang and H.W. Chang, 2010. Confronting two-pair primer design for enzyme-free SNP genotyping based on a genetic algorithm. BMC Bioinformat., Vol. 11. 10.1186/1471-2105-11-509.
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99:   Yang, C.H., Y.H. Cheng, L.Y. Chuang and H.W. Chang, 2011. A Combined Bisulfite Restriction Analysis Bioinformatics Tool: Methyl-Typing. In: Epigenetics Protocols, Tollefsbol, T.O. (Ed.). 2nd Edn., Humana Press, Totowa, NJ, USA., pp: 73-88.
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100:   Yang, C.H., Y.H. Cheng, L.Y. Chuang and H.W. Chang, 2013. Drug-SNPing: An integrated drug-based, protein interaction-based tagSNP-based pharmacogenomics platform for SNP genotyping. Bioinformatics, 29: 758-764.
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101:   Yang, H.L., Y.H. Kuo, C.T. Tsai, Y.T. Huang and S.C. Chen et al., 2011. Anti-metastatic activities of Antrodia camphorata against human breast cancer cells mediated through suppression of the MAPK signaling pathway. Food Chem. Toxicol., 49: 290-298.
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102:   Yang, H.P., T.C. Wang, S.J. Wang, S.P. Chen and E. Wu et al., 2013. Recombinant chimeric vaccine composed of PRRSV antigens and truncated Pseudomonas exotoxin A (PE-K13). Res. Vet. Sci., 95: 742-751.
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103:   Yang, J.F., C.H. Yang, H.W. Chang, C.S. Yang, C.W. Lin and L.Y. Chuang, 2009. Antioxidant and antibacterial properties of Pericarpium trichosanthis against nosocomial drug resistant strains of Acinetobacter baumannii in Taiwan. J. Med. Plants Res., 3: 982-991.
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104:   Yang, J.F., C.H. Yang, H.W. Chang, C.S. Yang, S.M. Wang, M.C. Hsieh and L.Y. Chuang, 2010. Chemical composition and antibacterial activities of Illicium verum against antibiotic-resistant pathogens. J. Med. Food, 13: 1254-1262.
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105:   Yang, J.I., C.C. Yeh, J.C. Lee, S.C. Yi, H.W. Huang, C.N. Tseng and H.W. Chang, 2012. Aqueous extracts of the edible Gracilaria tenuistipitata are protective against H2O2-induced DNA damage, growth inhibition and cell cycle arrest. Molecules, 17: 7241-7254.
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106:   Yang, J.I., H.Y. Huang, Y.C. Chou, C.C. Chen, G.C. Lee and H.W. Chang, 2011. Rapid and economic DNA extraction from a single salmon egg for real-time PCR amplification. Biosci. Biotechnol. Biochem., 75: 2014-2017.
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107:   Yeh, C.C., C.N. Tseng, J.I. Yang, H.W. Huang and Y. Fang et al., 2012. Antiproliferation and induction of apoptosis in Ca9-22 oral cancer cells by ethanolic extract of Gracilaria tenuistipitata. Molecules, 17: 10916-10927.
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108:   Yeh, C.C., J.I. Yang, J.C. Lee, C.N. Tseng and Y.C. Chan et al., 2012. Anti-proliferative effect of methanolic extract of Gracilaria tenuistipitata on oral cancer cells involves apoptosis, DNA damage, and oxidative stress. BMC Compl. Altern. Med., Vol. 12. 10.1186/1472-6882-12-142.
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109:   Yen, C.Y., C.C. Chiu, F.R. Chang, J.Y.F. Chen and C.C. Hwang et al., 2010. 4β-Hydroxywithanolide E from Physalis peruviana (golden berry) inhibits growth of human lung cancer cells through DNA damage, apoptosis and G2/M arrest. BMC Cancer, Vol. 10. 10.1186/1471-2407-10-46.
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110:   Yen, C.Y., C.C. Chiu, R.W. Haung, C.C. Yeh and K.J. Huang et al., 2012. Antiproliferative effects of goniothalamin on Ca9-22 oral cancer cells through apoptosis, DNA damage and ROS induction. Mutat. Res./Genet. Toxicol. Environ. Mutagen., 747: 253-258.
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111:   Yen, C.Y., C.H. Chen, C.H. Chang, H.F. Tseng and S.Y. Liu et al., 2009. Matrix metalloproteinases (MMP) 1 and MMP10 but not MMP12 are potential oral cancer markers. Biomarkers, 14: 244-249.
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112:   Yen, C.Y., C.Y. Huang, M.F. Hou, Y.H. Yang and C.H. Chang et al., 2013. Evaluating the performance of fibronectin 1 (FN1), integrin α4β1 (ITGA4), syndecan-2 (SDC2), and glycoprotein CD44 as the potential biomarkers of oral squamous cell carcinoma (OSCC). Biomarkers, 18: 63-72.
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113:   Yen, C.Y., M.C. Lu, C.C. Tzeng, J.Y. Huang and H.W. Chang et al., 2009. Detection of EBV infection and gene expression in oral cancer from patients in Taiwan by microarray analysis. J. Biomed. Biotechnol., 10.1155/2009/904589.
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114:   Yen, C.Y., S.Y. Liu, C.H. Chen, H.F. Tseng and L.Y. Chuang et al., 2008. Combinational polymorphisms of four DNA repair genes XRCC1, XRCC2, XRCC3 and XRCC4 and their association with oral cancer in Taiwan. J. Oral Pathol. Med., 37: 271-277.
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