Dr. Ashok Kumar Tiwari

Dr. Ashok Kumar Tiwari

Principal Investigator
Indian Institute of Chemical Technology, India


Highest Degree
Ph.D. in Zoology from Banaras Hindu University, India

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Biography

Dr. Ashok Kumar Tiwari is currently working as Principal Scientist at Indian Institute of Chemical Technology, India. He obtained his Ph.D. in Zoology from Banaras Hindu University, Varanasi, Uttar Pradesh, India. His main area of interest related to Metabolic Disorders and Development of Bio-Actives. He is member of editorial board in 6 scientific journals. He is life member of Indian Society for Atherosclerosis Research, Indian Society for Comparative Animal Physiology, and Banaras Hindu University Old Students Association. Dr. Ashok Kumar received honors includes 1st prize in IUPAC International conference on biodiversity and natural products, 2nd prize in Rastriya Vigyan Sangoshthi, held at NGRI, Best Poster Award In INDO-US CCNP-2006, Indo-US conference, and Awarded with the title International Scientist of the Year 2007 by International Biographical Centre, Cambridge, England. He has published 24 patents, more than 92 articles in journal as author/co-author. He also participated in 62 conferences and performed many presentations.

Area of Interest:

Food Science Technology
100%
Food Nutrition
62%
Food Chemistry
90%
Functional Food
75%
Dietetics
55%

Education

1992

Ph.D.

Banaras Hindu University, India

Zoology

1985

M.Sc.

Gorakhpur University, Uttar Pradesh, India

Zoology

1983

B.Sc.

Gorakhpur University, Uttar Pradesh, India

Zoology, Botany, Chemistry

Selected Publications

  1. Rao, R.R., V.U. Sarma, S. Satyanarayanaraju, K.S. Babu, A.K. Tiwari and J.M. Rao, 2013. Inhibitory effects of derris indica derived constituents against advanced glycation end products and their simultaneous determination by HPLC. J. Liquid Chromatogr. Relat. Technol., 36: 1631-1645.
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  2. Kumar, S.P., T.H. Babu, V.R.S. Rao, A.K. Tiwari, J.M. Rao and K.S. Babu, 2013. Novel C-9, 9ٰ-O-Acyl esters of (-)-carinol as free-radical scavengers and xanthine oxidase enzyme inhibitors: Synthesis and biological evaluation. Med. Chem., 9: 100-103.

  3. Kumar, J.A., A.K. Tiwari, G. Saidachary, D.A. Kumar, Z. Ali, B. Sridhar and B.C. Raju, 2013. New convenient approach for the synthesis of benzyl 2H-chromenones and their α-amylase Inhibitory, ABTS.+ scavenging activities. Med. Chem., 9: 806-811.
    PubMed  |  

  4. Tiwari, A.K., M.P. Kumar, D.A. Kumar, S.B. Agawane, K. Madhusudana and A. Zehra, 2012. Ayurvedic dietary formulations and postprandial glycemia in rats. Int. Food Res. J., 19: 765-773.
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  5. Suresh, G., A.K. Tiwari, M.R.K. Murthy, D.A. Kumar and K.R. Prasad et al., 2012. New advanced glycation end-products inhibitors from Dichrostachys cinerea Wight and Arn. J. Nat. Med., 66: 213-216.
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  6. Rao, R.R., A.K. Tiwari, P.P. Reddy, K.S. Babu and G. Suresh et al., 2012. Synthesis of antihyperglycemic, α-glucosidase inhibitory, and DPPH free radical scavenging furanochalcones. Med. Chem. Res., 21: 760-774.
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  7. Pal-Bhadra, M., M.J. Ramaiah, T.L. Reddy, A. Krishnan and S.N.C.V.L. Pushpavalli et al., 2012. Plant HDAC inhibitor chrysin arrest cell growth and induce p21WAF1 by altering chromatin of STAT response element in A375 cells. BMC Cancer, Vol. 12. 10.1186/1471-2407-12-180.
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  8. Misra, S., K.B. Pandeya, A.K. Tiwari, A.Z. Ali, T. Saradamani, S.B. Agawane and K. Madhusudana, 2012. α-Glucosidase inhibitory activities of some Oxovanadium (IV) complexes: Examples of low IC50 values. Int. J. Nutr. Metab., 4: 11-18.
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  9. Tiwari, A.K., M. Swapna, S.B. Ayesha, A. Zehra, S.B. Agawane and K. Madhusudana, 2011. Identification of proglycemic and antihyperglycemic activity in antioxidant rich fraction of some common food grains. Int. Food Res. J., 18: 915-923.
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  10. Tiwari, A.K., K.S. Reddy, J. Radhakrishnan, D.A. Kumar, A. Zehra, S.B. Agawane and K. Madhusudana, 2011. Influence of antioxidant rich fresh vegetable juices on starch induced postprandial hyperglycemia in rats. Food Funct., 2: 521-528.
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  11. Tiwari, A.K., 2011. Diabetes: Time to look beyond gluttony and laziness. Indian J. Community Med., 36: 253-258.
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  12. Tiwari, A.K., 2011. Diabetes: The Chronic Health Hazards of Non Organic Farming. In: Organic Farming, Singh, A. (Ed.). Chapter 20. Pointer Publishers, Jaipur, India, pp: 241-247.

  13. Tiwari, A.K., 2011. Diabetes: The Chronic Health Hazards of Non Organic Farming. In: Organic Farming, Singh, A. (Ed.). Chapter 20, Pointer Publishers, Jaipur, India, ISBN: 978-81-7132-667-1, pp: 241-247.

  14. Misra, S., K.B. Pandeya, A.K. Tiwari, A.Z. Ali and T. Saradamani, 2011. α-Glucosidase inhibition and DPPH free radical scavenging by oxovanadium(IV)complexes of some tetradentate Schiff bases. J. Indian Chem. Soc., 88: 1195-1201.

  15. Misra, S., K.B. Pandeya, A.K. Tiwari, A.Z. Ali and T. Saradamani et al., 2011. Antihyperglycemic, α-glucosidase inhibitory and DPPH free radical scavenging activity of 5-bromosalicylaldehyde and schiff bases. Med. Chem. Res., 20: 1431-1437.
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  16. Kumar, T.V., A.K. Tiwari, K.S. Babu, A. Robinson and R.S.C. Kumar et al., 2011. Synthesis and antiglycation potentials of Bergenin derivatives. Bioorg. Med. Chem. Lett., 21: 4928-4931.
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  17. Kumar, J.A., A.K. Tiwari, A.Z. Ali, R.R. Rao and B.C. Raju, 2011. Synthesis and α-glucosidase inhibitory, DPPH scavenging activity of substituted-2-oxo-2H-7-chromenyldi-hydrogen phosphate derivatives. J. Heterocyclic Chem., 48: 1251-1257.

  18. Tiwari, A.K., V. Viswanadh, P.M. Gowri, A.Z. Ali and S.V.S. Radhakrishnan et al., 2010. Oleanolic acid, an α-glucosidase inhibitory and antihyperglycemic active compound from the fruits of Sonneratia caseolaris. Open Access J. Med. Aromatic Plants, 1: 19-23.
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  19. Raju, B.C., A.K. Tiwari, J.A. Kumar, A.Z. Ali, S.B. Agawane, G. Saidachary and K. Madhusudana, 2010. α-Glucosidase inhibitory antihyperglycemic activity of substituted chromenone derivatives. Bioorg. Med. Chem., 18: 358-365.
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  20. Narasimhulu, M., K. Ashalatha, P.S. Laxmi, A.V. Sarma and B.R. Rao et al., 2010. An unusual novel anti-oxidant dibenzoyl glycoside from Salvinia natans. Nat. Prod. Res., 24: 1390-1394.
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  21. Kumbhare, R.M., U. Kosurkar, K.V. Kumar, T. Dadmal and A.K. Tiwari, 2010. Synthesis of multiple biologically active 1,2-dihydro-pyrimido [1,2-A]-benzimidazole-3-carbonitrile. Int. J. Appl. Biol. Pharm. Technol., 1: 729-735.
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  22. Kumar, J.A., A.K. Tiwari, A.Z. Ali, K. Madhusudhana, B.S.Reddy, S. Ramakrishna and B.C. Raju, 2010. New antihyperglycemic, α-glucosidase inhibitory and cytotoxic derivatives of benzimidazoles. J. Enzyme Inhibition Med. Chem., 25: 80-86.
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  23. Kumar, G.S., A.K. Tiwari, V.R. Rao, K.R. Prasad, A.Z. Ali and K.S. Babu, 2010. Synthesis and biological evaluation of novel benzyl-substituted flavones as free radical (DPPH) scavengers and α-glucosidase inhibitors. J. Asian Nat. Prod. Res., 12: 978-984.
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  24. Babu, T.H., K. Manjulatha, G.S. Kumar, A. Hymavathi and A.K. Tiwari et al., 2010. Gastroprotective flavonoid constituents from Oroxylum indicum Vent. Bioorg. Med. Chem. Lett., 20: 117-120.
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  25. Babu, T.H., A.K. Tiwari, V.R.S. Rao, A.Z. Ali, J.M. Rao and K.S. Babu, 2010. A new prenylated isoflavone from Derris scandens Benth. J. Asian Nat. Prod. Res., 12: 634-638.
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  26. Reddy, P.P., A.K. Tiwari, R.R. Rao, K. Madhusudana and V.R.S. Rao et al., 2009. New labdane diterpenes as intestinal α-glucosidase inhibitor from antihyperglycemic extract of Hedychium spicatum (Ham. Ex Smith) rhizomes. Bioorg. Med. Chem. Lett., 19: 2562-2565.
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  27. Rao, R.R., A.K. Tiwari, P.P. Reddy, K.S. Babu, A.Z. Ali, K. Madhusudana and J.M. Rao, 2009. New furanoflavanoids, intestinal α-glucosidase inhibitory and free-radical (DPPH) scavenging, activity from antihyperglycemic root extract of Derris indica (Lam.). Bioorg. Med. Chem., 17: 5170-5175.
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  28. Aparna, P., A.K. Tiwari, P.V. Srinivas, A.Z. Ali, V. Anuradha and J.M. Rao, 2009. Dolichandroside A, a new α-glucosidase inhibitor and DPPH free-radical scavenger from Dolichandrone falcata seem. Phytother. Res., 23: 591-596.
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  29. Tiwari, A.K., R.M. Kumbhare, S.B. Agawane, A.Z. Ali and K.V. Kumar, 2008. Reduction in post-prandial hyperglycemic excursion through α-glucosidase inhibition by β-acetamido carbonyl compounds. Bioorg. Med. Chem. Lett., 18: 4130-4132.
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  30. Tiwari, A.K., 2008. Invigorated barley in diabetes. Curr. Sci., 95: 25-29.
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  31. Tiwari, A.K., 2008. Diabetic epidemic: Consequences of luxury and wealth. Proceeding of the National Conference on Acharya Jagadish Chandra Bose and Ancient Indian Thought, December 21, 2008, Institute of Scientific Research on Vedas (ISERVE), Hyderabad, India, pp: 68-72.

  32. Babu, T.H., V.R.S. Rao, A.K. Tiwari, K.S. Babu, P.V. Srinivas, A.Z. Ali and J.M. Rao, 2008. Synthesis and biological evaluation of novel 8-aminomethylated oroxylin A analogues as α-glucosidase inhibitors. Bioorg. Med. Chem. Lett., 18: 1659-1662.
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  33. Tiwari, A.K., P.V. Srinivas, A.Z. Ali, T.H. Babu, K.J. Nehru, S.B. Agawane and J.M. Rao, 2007. Possibility of cost effective management of post prandial hyperglycemic excursion by some common spices. Indian J. Arecanut Spices Med. Plants, 9: 172-178.

  34. Tiwari, A.K., 2007. Lavender and tea-tree oils induced gynecomastia in prepubertal children warrants prudent use of herbal products. Curr. Sci., 93: 287-287.

  35. Tiwari, A.K., 2007. Karela: A promising antidiabetic vegetable therapy. Curr. Sci., 92: 1697-1701.
    Direct Link  |  

  36. Srinivas, P.V., A.K. Tiwari, T. Sreelatha, K.S. Babu, R.J. Rao and J.M. Rao, 2007. Isolation and Synthesis of µ-Glucosidase Inhibitor, (-) Epiafzelechin from Cassia marginata Roxb. In: Advances in Medicinal Plants, Reddy, K.J., B. Bahadur, B. Bhadraiah and M.L.N. Rao (Eds.). University Press Pvt Ltd., India, pp: 320.

  37. Rao, S.A., P.V. Srinivas, A.K. Tiwari, U.M.S. Vanka, R.V.S. Rao, K.R. Dasari and M.J. Rao, 2007. Isolation, characterization and chemobiological quantification of α-glucosidase enzyme inhibitory and free radical scavenging constituents from Derris scandens Benth. J. Chromatogr. B, 855: 166-172.
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  38. Mallur, S.G., A.K. Tiwari, B.C. Raju, K.S. Babu, A.Z. Ali, B.S. Sastry and J.M. Rao, 2007. Synthesis and evaluation of phenyl substituted sydnones as potential DPPH-radical scavengers. Ind. J. Chem., 46B: 1686-1689.
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  39. Gowri, P.M., A.K. Tiwari, A.Z. Ali and J.M. Rao, 2007. Inhibition of alpha-glucosidase and amylase by bartogenic acid isolated from Barringtonia racemosa Roxb. seeds. Phytother. Res., 21: 796-799.
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  40. Tiwari, A.K., 2006. Panorama of Tuvarak Seed Hulls in Holistic Management of Diabetes. In: Chronic Inflammatory Diseases and Nutraceuticals (Molecular Mechanism of Chronic Diseases, New Targets and Basic Concepts of Ayurveda), Tripathi, Y.B. (Ed.). S.N. Tripathi Memorial Foundation, Varanasi, India.

  41. Tiwari, A.K., 2006. Ayurveda will survive till Bharat breathes. Curr. Sci., 90: 1589-1590.
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  42. Pullela, S.V., A.K. Tiwari, U.S. Vanka, A. Vummenthula and H.B. Tatipaka et al., 2006. HPLC assisted chemobiological standardization of α-glucosidase-I enzyme inhibitory constituents from Piper longum Linn-An indian medicinal plant. J. Ethnopharmacol., 108: 445-449.
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  43. Tiwari, A.K., 2005. Wisdom of ayurveda in perceiving diabetes: Enigma of therapeutic recognition. Curr. Sci., 88: 1043-1051.
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  44. Srinivas, P.V., V. Anuradha, A.K. Tiwari and J.M. Rao, 2005. Research towards finding reasons for the traditional usage of pepper. J. Pepper Ind. Focus Pepper, 2: 21-26.
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  45. Reddy, S.V., A.K. Tiwari, U.S. Kumar, R.J. Rao and J.M. Rao, 2005. Free radical scavenging, enzyme inhibitory constituents from antidiabetic Ayurvedic medicinal plant Hydnocarpus wightiana Blume. Phytother. Res., 19: 277-281.
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  46. Rao, R.J., U.S. Kumar, S.V. Reddy, A.K. Tiwari and J.M. Rao, 2005. Antioxidants and a new germacrane sesquiterpene from Carissa spinarum. Nat. Prod. Res., 19: 763-769.
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  47. Kumar, U.S., A.K. Tiwari, S.V. Reddy, P. Aparna, R.J. Rao, A.Z. Ali and J.M. Rao, 2005. Free-radical-scavenging and xanthine oxidase inhibitory constituents from Stereospermum personatum. J. Nat. Prod., 68: 1615-1621.
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  48. Tiwari, A.K., 2004. Antioxidants: New-generation therapeutic base for treatment of polygenic disorders. Curr. Sci., 86: 1092-1102.
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  49. Babu, K.S., A.K. Tiwari, P.V. Srinivas, A.Z. Ali, B.C. Raju and J.M. Rao, 2004. Yeast and mammalian α-glucosidase inhibitory constituents from Himalayan Rhubarb Rheum emodi Wall.ex Meisson. Bioorg. Med. Chem. Lett., 14: 3841-3845.
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  50. Tiwari, A.K., 2003. Adverse effects of antioxidants. Curr. Sci., 85: 1111-1117.

  51. Jagadeeshwar, R.R., A.K. Tiwari, U.S. Kumar, S.V. Reddy, A.Z. Ali and J.M. Rao, 2003. Novel 3-O-acyl mesquitol analogues as free-radical scavengers and enzyme inhibitors: Synthesis, biological evaluation and structure-activity relationship. Bioorg. Med. Chem. Lett., 13: 2777-2780.
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  52. Tiwari, A.K. and J.M. Rao, 2002. Diabetes mellitus and multiple therapeutic approaches of phytochemicals: Present status and future prospects. Curr. Sci., 83: 30-38.
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  53. Kumar, U.S., A.K. Tiwari, S.V. Reddy, R.J. Rao, Z. Ali and J.M. Rao, 2002. Bioassay Guided Isolation of Free Radical Scavenging and Xanthin Oxidase Inhibitory Compounds from Stereospermum personatum, an Ayurvedic Medicinal Plant. In: Utilizations of Bioresources, Sree, A., Y.R. Rao, B. Nanda and V.N. Mishra (Eds.). Allied Publishers Pvt. Ltd., New Delhi-64, India, pp: 32-37.

  54. Tiwari, A.K., P.V. Srinivas, S.P. Kumar and J.M. Rao, 2001. Free radical scavenging active components from Cedrus deodara. J. Agric. Food Chem., 49: 4642-4645.
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  55. Tiwari, A.K., 2001. Imbalance in antioxidant defense and human diseases: Multiple approach of natural antioxidants therapy. Curr. Sci., 81: 1179-1187.
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