Dr. Jayati Roy Choudhury

Dr. Jayati Roy Choudhury

Research Scientist
University of Texas Medical Branch, USA


Highest Degree
Ph.D. in Chemistry from Wake Forest University, USA

Share this Profile

Area of Interest:

Chemistry
100%
Biochemistry
62%
Molecular Biology
90%
Organic Chemistry
75%
Medicinal Chemistry
55%

Education

2008

Ph.D.

Wake Forest University, USA

Chemistry

Selected Publications

  1. Carpio, R.V., T.D. Silverstein, S. Lone, M.K. Swan and J.R. Choudhury et al., 2009. Structure of human DNA polymerase κ inserting dATP opposite an 8-OxoG DNA lesion. Plos One., 4: e5766-e5766.
    CrossRef  |  PubMed  |  Direct Link  |  

  2. Zhidong, M., J.R. Choudhury, M.W. Wright, C.S. Day, G. Saluta, G.L. Kucera and U. Bierbach, 2008. A non-cross-linking platinum-acridine agent with potent activity in non-small-cell lung cancer. J. Med. Chem., 51: 7574-7580.
    CrossRef  |  PubMed  |  Direct Link  |  

  3. Choudhury, J.R., R. Guddneppanavar, G. Saluta, G.L. Kucera and U. Bierbach, 2008. Tuning the DNA conformational perturbations induced by cytotoxic platinum-acridine bisintercalators: Effect of metal cis/trans isomerism and DNA threading groups. J. Med. Chem., 51: 3069-3072.
    CrossRef  |  PubMed  |  Direct Link  |  

  4. Zhidong, M., J.R. Choudhury, G.L. Kucera, G. Saluta and U. Bierbach, 2007. Tuning the reactivity and DNA interactions of platinum-acridine hybrid agents. Proceedings of the 59th Southeast Regional Meeting of American Chemical Society, Greenville, SC, October 24-27..

  5. Guddneppanavar, R., J.R. Choudhury, A.R. Kheradi, B.D. Steen and G. Saluta et al., 2007. Effect of the diamine nonleaving group in platinum-acridinylthiourea conjugates on DNA damage and cytotoxicity. J. Med. Chem., 50: 2259-2263.
    CrossRef  |  PubMed  |  Direct Link  |  

  6. Choudhury, J.R., R. Guddneppanavar, G.L. Kucera, G. Saluta and U. Bierbach, 2007. DNA conformational changes induced by a highly charged, cytotoxic platinum-based bisintercalator. Proceedings of the 59th Southeast Regional Meeting of American Chemical Society, Greenville, SC, October 24-27..

  7. Choudhury, J.R., M.E. Budiman, R.W. Alexander and U. Bierbach, 2005. DNA sequence and groove recognition by platinum-acridine conjugates. Proceedings of the International Conference on Biological Inorganic Chemistry, Ann Arbor, MI, August 1-5..

  8. Choudhury, J.R. and U. Bierbach, 2005. Characterization of the bisintercalative DNA binding mode of a bifunctional platinum-acridine agent. Nucleic Acids Res., 33: 5622-5632.
    CrossRef  |  PubMed  |  Direct Link  |  

  9. Choudhury, J.R., M.E. Budiman, R.W. Alexander and U. Bierbach, 2004. DNA sequence and groove recognition by platinum-acridine conjugates. Proceedings of the 56th Southeast Regional Meeting of American Chemical Society, Raleigh, NC, November 3-5..