Prof. Dr. Surya Pratap Singh
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Prof. Dr. Surya Pratap Singh

Professor
Banaras Hindu University, India


Highest Degree
Ph.D. in Biochemistry from Banaras Hindu University, India

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Area of Interest:

Biomedical Sciences
100%
Biodegradation
62%
Pharmaceutics
90%
Biochemistry
75%
Biotechnology
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Yadav, S.K., S.N. Rai and S.P. Singh, 2017. Mucuna pruriens reduces inducible nitric oxide synthase expression in Parkinsonian mice model. J. Chem. Neuroanatomy, 80: 1-10.
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  2. Tiwari, N., M.R. Gedda, V.K. Tiwari, S.P. Singh and R.K. Singh, 2017. Limitations of current therapeutic options, possible drug targets and scope of natural products in control of leishmaniasis. Mini Rev. Med. Chem., Vol. 17. 10.2174/1389557517666170425105129 .
    CrossRef  |  PubMed  |  Direct Link  |  
  3. Singh, N., M.R. Gedda, N. Tiwari, S.P. Singh, S. Bajpai and R.K. Singh, 2017. Solute carrier protein family 11 member 1 (Slc11a1) activation efficiently inhibits Leishmania donovani survival in host macrophages. J. Parasitic Dis., 41: 671-677.
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  4. Yadav, S.K., S.N. Rai and S.P. Singh, 2016. Mucuna pruriens shows neuroprotective effect by inhibiting apoptotic pathways of dopaminergic neurons in the paraquat mouse model of parkinsonism. Eur. J. Pharm. Med. Res., 3: 441-451.
  5. Westfall, S., N. Lomis, S.P. Singh and S. Prakash, 2016. Ferulic acid produced by Lactobacillus fermentum NCIMB 5221 reduces symptoms of metabolic syndrome in drosophila melanogaster. J. Microb. Biochem. Technol., 8: 272-284.
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  6. Rai, S.N., S.K. Yadav, D. Singh and S.P. Singh, 2016. Ursolic acid attenuates oxidative stress in nigrostriatal tissue and improves neurobehavioral activity in MPTP-induced Parkinsonian mouse model. J. Chem. Neuroanatomy, 71: 41-49.
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  7. Rai, S.N. and S.P. Singh, 2016. Comparison of the neuroprotective potential of estrogen and levodopa in 1-methyl-4-phenyl-l,2,3,6-tetrahydropyridine (MPTP)-induced cognitive deficit in parkinsonian mice model. Eur. J. Pharm. Med. Res., 3: 317-328.
  8. Patil, R.R., S.N. Rai, J.P. Jadhav and S.P. Singh, 2016. Mucuna sanjappae shows promising anti-parkinson’s activity by reducing oxidative stress in MPTP induced mouse model. Eur. J. Pharm. Med. Res., 3: 452-463.
  9. Westfall, S., N. Lomis, S.P. Singh, S.Y. Dai and S. Prakash, 2015. The gut microflora and its metabolites regulate the molecular crosstalk between diabetes and neurodegeneration. Diabetes Metab., Vol. 6. 10.4172/2155-6156.1000577.
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  10. Pant, J., M.K. Pant, S. Chouhan, S.P. Singh and S.B. Deshpande, 2015. Toxic chemical from plastics attenuates phenylbiguanide-induced cardio-respiratory reflexes in anaesthetized rats. Indian J. Physiol. Pharmacol., 59: 204-210.
    Direct Link  |  
  11. Chouhan, S., S.K. Yadav, J. Prakash, S. Westfall, A. Ghosh, N.K. Agarwal and S.P. Singh, 2015. Increase in the expression of inducible nitric oxide synthase on exposure to bisphenol A: A possible cause for decline in steroidogenesis in male mice. Environ. Toxicol. Pharmacol., 39: 405-416.
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  12. Chauhan, A.K., A. Ahmad, S.P. Singh and A. Kumar, 2015. Nucleotide sequencing of dszABC genes from a desulfurizing strain Mycobacterium phlei SM120-1. Int. J. Applied Biochem., 3: 1-5.
  13. Chauhan, A.K., A. Ahmad, S.P. Singh and A. Kumar, 2015. Biodesulfurization of benzonaphthothiophene by an isolated Gordonia sp. IITR100. Int. Biodeterior. Biodegrad., 104: 105-111.
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  14. Yadav, S.K., J. Prakash, S. Chouhan, S. Westfall, M. Verma, T.D. Singh and S.P. Singh, 2014. Comparison of the neuroprotective potential of Mucuna pruriens seed extract with estrogen in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced PD mice model. Neurochem. Int., 65: 1-13.
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  15. Prakash, J., S. Chouhan, S.K. Yadav, S. Westfall, S.N. Rai and S.P. Singh, 2014. Withania somnifera alleviates Parkinsonian phenotypes by inhibiting apoptotic pathways in dopaminergic neurons. Neurochem. Res., 9: 2527-2536.
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  16. Keswani, C., S. Mishra, B.K. Sarma, S.P. Singh and H.B. Singh, 2014. Unraveling the efficient applications of secondary metabolites of various Trichoderma spp. Applied Microbiol. Biotechnol., 98: 533-544.
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  17. Chouhan, S., S.K. Yadav, J. Prakash and S.P. Singh, 2014. Effect of Bisphenol A on human health and its degradation by microorganisms: A review. Ann. Microbiol., 64: 13-21.
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  18. Chauhan, A.K., S.P. Singh and A. Kumar, 2014. Cloning, sequencing and characterization of the ‘desulfurization gene cluster’ from an isolated strain Gordonia sp. IITR100. J. Applied Biotechnol., 2: 65-74.
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  19. Yadav, S.K., J. Prakash, S. Chouhan and S.P. Singh, 2013. Mucuna pruriens seed extract reduces oxidative stress in nigrostriatal tissue and improves neurobehavioral activity in paraquat-induced Parkinsonian mouse model. Neurochem. Int., 62: 1039-1047.
    CrossRef  |  Direct Link  |  
  20. Prakash, J., S.K. Yadav, S. Chouhan, S. Prakash and S.P. Singh, 2013. Synergistic effect of Mucuna pruriens and Withania somnifera in a paraquat induced Parkinsonian mouse model. Adv. Biosci. Biotechnol., 4: 1-9.
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  21. Prakash, J., S.K. Yadav, S. Chouhan and S.P. Singh, 2013. Neuroprotective role of Withania somnifera root extract in Maneb-Paraquat induced mouse model of parkinsonism. Neurochem. Res., 38: 972-980.
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  22. Keswani, C., S.P. Singh and H.B. Singh, 2013. Beauveria bassiana: Status, mode of action, applications and safety issues. Biotech Today, 3: 16-20.
  23. Gupta, P., R. Goel, A.V. Agarwal, S. Pathak and A. Srivastava et al., 2013. De novo assembly, functional annotation and comparative analysis of Withania somnifera leaf and root transcriptomes to identify putative genes involved in the withanolides biosynthesis. PLoS One, Vol. 8. 10.1371/journal.pone.0062714.
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  24. Gupta, P., A.V. Agarwal, N. Akhtar, R.S. Sangwan, S.P. Singh and P.K. Trivedi, 2013. Cloning and characterization of 2-C-methyl-D-erythritol-4-phosphate pathway genes for isoprenoid biosynthesis from Indian ginseng, Withania somnifera. Protoplasma, 250: 285-295.
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  25. Chouhan, S., J. Prakash, S. Yadav, S.P. Singh and N. Agrawal, 2013. Effect of Bisphenol A on fertility of male mice. J. Scient. Res., 57: 77-84.
  26. Singh, S.P., A. Wolfe, Y. Ng, S.A. DiVall and C. Buggs et al., 2009. Impaired estrogen feedback and infertility in female mice with pituitary-specific deletion of estrogen receptor alpha (ESR1). Biol. Reprod., 81: 488-496.
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  27. Wolfe, A., Y. Ng, S.A. Divall, S.P. Singh and S. Radovick, 2008. Development of an immortalised, post‐pubertal gonadotrophon‐releasing hormone neuronal cell line. J. Neuroendocrinol., 20: 1029-1037.
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  28. Wolfe, A., S. Divall, S.P. Singh, A.A. Nikrodhanond and A.T. Baria et al., 2008. Temporal and spatial regulation of CRE recombinase expression in gonadotrophin‐releasing hormone neurones in the mouse. J. Neuroendocrinol., 20: 909-916.
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  29. Singh, S.P., D. McDonald, T.J. Hope and B.S. Prabhakar, 2004. Upon thyrotropin binding the thyrotropin receptor is internalized and localized to endosome. Endocrinology, 145: 1003-1010.
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  30. Ramaswamy, M., E.V. Efimova, O. Martinez, N.U. Mulherkar, S.P. Singh and B.S. Prabhakar, 2004. IG20 (MADD Splice Variant-5), a pro-apoptotic protein, interacts with DR4/DR5 and enhances TRAIL induced apoptosis by increasing recruitment of FADD and caspase-8 to the DISC. Oncogene, 23: 6083-6094.
    Direct Link  |  
  31. Gomes, I., A. Gupta, S.P. Singh and S.K. Sharma, 1999. Monoclonal antibody to the δ opioid receptor acts as an agonist in dual regulation of adenylate cyclase in NG108‐15 cells. FEBS Lett., 456: 126-130.
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  32. Singh, S.P. and R. Shankar, 1996. Effect of haloperidol on phospholipid biosynthesis in rat brain. Indian J. Exp. Biol., 34: 111-114.
    PubMed  |  
  33. Ralhan, R., J. Kaur, P.T. Chelvi, S.P. Singh and H. Zeba, 1995. Heat stress stimulates high affinity GTPase in cervical carcinoma cells. Int. J. Biochem. Cell Biol., 27: 263-269.
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  34. Singh, S.P. and R. Shankar, 1994. Effect of haloperidol on phospholipid turn over in rat brain in vitro. J. Neurochem., 63: S32-S32.