Dr. Mallikarjuna  Rao Pichika

Dr. Mallikarjuna Rao Pichika

Professor, Associate Dean
International Medical University, Malaysia


Highest Degree
Ph.D. in Pharmaceutical Sciences from Andhra University, India

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Area of Interest:

Pharmacology and Toxicology
100%
Pharmaceutical Sciences
62%
Clinical Research
90%
Drug Delivery
75%
Medicine
55%

Selected Publications

  1. Rathinasabapathy, T., K.M.P. Jackson, Y. Thor, A.S. Buru and D. Esposito et al., 2017. Thiazolopyridines improve adipocyte function by inhibiting 11 Beta-HSD1 oxoreductase activity. J. Chem., Vol. 2017. 10.1155/2017/3182129.
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  2. Meka, V.S., M.K. Sing, M.R. Pichika, S.R. Nali, V.R. Kolapalli and P. Kesharwani, 2017. A comprehensive review on polyelectrolyte complexes. Drug Discovery Today, 22: 1697-1706.
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  3. Kun, N.C., L.A. Wei, C.J. Wei, L.L. Jie, M.R. Pichika and L.S.H. Erin, 2017. An evaluation of antimicrobial activity of different extracts of Dillenia suffruticosa stem bark. Int. Med. J., 24: 104-110.

  4. Kandasamy, M., M. Salihin, M.R. Pichika, S. Komarnytsky and T. Rathinasabapathy, 2017. A metabolic stability determination of tetrahydrothiazolopyridine derivate: A selective 11 - hydroxysteroiddehydrogenase type 1 (11B-HSD1) inhibitor. Int. J. Pharm. Bio Sci., 8: 120-130.
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  5. Balijepalli, M.K., A.S. Buru, R. Sakirolla and M.R. Pichika, 2017. Cinnamomum genus: A review on its biological activities. Int. J. Pharm. Pharm. Sci., 9: 1-11.

  6. Rajasingam, R., S.R. Sagineedu, Y.H. Tan, N. Jeyashanthini and M.R. Pichika, 2016. Stress degradation studies and development of a validated RP-HPLC method for determination of tiagabine in presence of its degradation products. Int. J. Pharm. Pharm. Sci., 8: 230-236.

  7. Mahita, J., K. Harini, M.R. Pichika and R. Sowdhamini, 2016. An in silico approach towards the identification of novel inhibitors of the TLR-4 signaling pathway. J. Biomolecular Structure Dynamics, 34: 1345-1362.
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  8. Mai, C.W., R. Anitha, J.J.L. Tiong, P.K. Lai, M.R. Pichika and A.I. Gray, 2015. Chemistry content in the pharmacy curriculum: Relevance to develop pharmacists fit-to-work in diverse pharmacy profession sectors. Indian J. Pharm. Educ. Res., 49: 240-247.
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  9. Kaki, V.R., R.R. Akkinepalli, P.K. Deb and M.R. Pichika, 2015. Basic ionic liquid [bmIm] OH-mediated Gewald reaction as green protocol for the synthesis of 2-aminothiophenes. Synthetic Commun., 45: 119-126.
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  10. Jeyashanthini, N., S.R. Sagineedu, R. Rajasingam, Z. Kassim and M.R. Pichika, 2015. A Stability-indicating RP-HPLC method for simultaneous determination of simvastatin and niacin in a combined dosage form. Int. J. Pharm. Pharm. Sci., 7: 262-268.

  11. Balijepalli, M.K., V. Suppaiah, A.M. Chin, A.S. Buru, S.R. Sagineedu and M.R. Pichika, 2015. Acute oral toxicity studies of Swietenia macrophylla seeds in sprague dawley rats. Pharm. Res., 7: 38-44.
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  12. Mai, C.W., M. Yaeghoobi, N. Abd-Rahman, Y.B. Kang and M.R. Pichika, 2014. Chalcones with electron-withdrawing and electron-donating substituents: Anticancer activity against TRAIL resistant cancer cells, structure–activity relationship analysis and regulation of apoptotic proteins. Eur. J. Med. Chem., 77: 378-387.
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  13. Deb, P.K., D. El-Rabie, A. Junaid, L.C. Siong, A. Kulasekar, L. Kulasingam and M.R. Pichika, 2014. In silico binding mode analysis (Molecular docking studies) and absorption, distribution, metabolism and excretion prediction of some novel inhibitors of aurora kinase a in clinical trials. Asian J. Chem., 26: 6221-6226.

  14. Deb, P.K., A. Junaid, D. El-Rabie, T.Y. Hon, E.M. Nasr and M.R. Pichika, 2014. Molecular docking studies and comparative binding mode analysis of FDA approved HIV protease inhibitors. Asian J. Chem., 26: 6227-6232.

  15. Buru, A.S., M.R. Pichika, V. Neela and K. Mohandas, 2014. In vitro antibacterial effects of Cinnamomum extracts on common bacteria found in wound infections with emphasis on methicillin-resistant Staphylococcus aureus. J. Ethnopharmacol., 153: 587-595.
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  16. Yap, P.S.X., Y.T.E. Chong, Y.Y. Wong, X.Y. Lim and J.H. Ang et al., 2013. Antibacterial and antifungal testing of the different extracts of Dillenia obovata (Blue) Hoogl. World J. Pharm. Pharm. Sci., 2: 3946-3962.

  17. Tan, B.S., O. Kang, C.W. Mai, K.H. Tiong and A.S.B. Khoo et al., 2013. 6-Shogaol inhibits breast and colon cancer cell proliferation through activation of peroxisomal proliferator activated receptor γ (PPARγ). Cancer Lett., 336: 127-139.
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  18. Pichika, M.R., Y.B. Kang and S.W. Ng, 2013. 2-Methoxy-4-(prop-2-en-1-yl) phenyl benzoate. Acta Crystallographica Sect. E: Structure Rep. Online, Vol. 69. 10.1107/S1600536813015791.
    CrossRef  |  

  19. Pichika, M.R., Y.B. Kang and S.W. Ng, 2013. 2-Methoxy-4-(prop-2-en-1-yl) phenyl 2, 4-dichlorobenzoate. Acta Crystallographica Sect. E: Structure Rep. Online, Vol. 69. 10.1107/S1600536813015675.
    CrossRef  |  

  20. Pichika, M.R., B.K. Yew and S.W. Ng, 2013. 2-Methoxy-4-(prop-2-en-1-yl) phenyl 4-methoxybenzoate. Acta Crystallographica Sect. E: Structure Rep. Online, Vol. 69. 10.1107/S1600536813011458.
    CrossRef  |  

  21. Mai, C.W., Y.B. Kang and M.R. Pichika, 2013. Should a Toll-like receptor 4 (TLR-4) agonist or antagonist be designed to treat cancer? TLR-4: Its expression and effects in the ten most common cancers. OncoTargets Therapy, 6: 1573-1587.
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  22. Kishore, D.P., R. Maillabaram, A.R. Rao and P.M. Rao, 2013. Antiinflammatory evaluation and docking studies of some new thienopyrimidines. Asian J. Chem., 25: 10583-10587.

  23. Kishore, D.P., A. Rana, U.K. Jain and P.M. Rao, 2013. Pharmacophore-based 3D-QSAR studies of aromatase inhibitors. Asian J. Chem., 25: 10588-10594.

  24. Erin, L.S.H., P.P. Mun, N.S. Ling, O.C. Ping and S.X. Jie et al., 2013. Evaluation of four extracts of Dillenia ovata stem bark and leaves for antibacterial and antifungal activity. Int. J. Pharm. Pharm. Sci., 5: 471-474.

  25. Haw, K.Y., S. Chakravarthi, N. Haleagrahara and M. Rao, 2012. Effects of Etlingera elatior extracts on lead acetate-induced testicular damage: A morphological and biochemical study. Exp. Ther. Med., 3: 99-104.
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  26. Srinivasan, R., W.H. Wong and M.R. Pichika, 2011. Impact of extraction processes on the 6-shogaol content in Zingiber officinale (Halia Penang) and its antiproliferative activities on human colorectal cancer cell lines (HT-29). Planta Med., Vol. 77. 10.1055/s-0031-1273641.
    CrossRef  |  

  27. Katyayani, B.M., T. Satyanarayana and P.M. Rao, 2010. Antiproliferative and induction of apoptosis in estorgen-receptor positive and negative human breast carcinoma cell lines by Gmelina asiatica roots. Pharm. Res., 2: 113-119.

  28. Haleagrahara, N., T. Jackie, S. Chakravarthi, M. Rao and T. Pasupathi, 2010. Protective effects of Etlingera elatior extract on lead acetate-induced changes in oxidative biomarkers in bone marrow of rats. Food Chem. Toxicol., 48: 2688-2694.
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  29. Dugasani, S., M.R. Pichika, V.D. Nadarajah, M.K. Balijepalli, S. Tandra and J.N. Korlakunta, 2010. Comparative antioxidant and anti-inflammatory effects of [6]-gingerol,[8]-gingerol,[10]-gingerol and [6]-shogaol. J. Ethnopharmacol., 127: 515-520.
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  30. Dugasani, S., M.K. Balijepalli, S. Tandra and M.R. Pichika, 2010. Antimicrobial activity of Bauhinia tomentosa and Bauhinia vahlii roots. Pharm. Mag., 6: 204-207.
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  31. Balijepalli, M.K., C.Y. Rou and M.R. Pichika, 2010. Antiproliferative activity of Bauhinia blakeana on estrogen receptor negative human breast cancer (MDA-MB-231) cells. Planta Med., Vol. 76. 10.1055/s-0030-1251857.
    CrossRef  |  

  32. Adinarayana, K., K.N. Jayveera and M.R. Pichika, 2010. Evaluation of antiulcerogenic activity of Tephrosia calophylla roots on aspirin plus pyloric ligation-induced ulcers in experimental rats. Planta Med., Vol. 76. 10.1055/s-0030-1251856.
    CrossRef  |  

  33. Swarnalatha, D., B.M. Katyayani and P.M. Rao, 2009. Growth inhibition and induction of apoptosis in estrogen receptor-positive and negative human breast carcinoma cells lines by Adenocalymma alliaceum. Curr. Trends Biotechnol. Pharm., 3: 278-286.

  34. Sreenivasulu, V., P.M. Rao and K.N. Jayaveera, 2009. Mutation induced enhanced biosynthesis of antitumour L-asparaginase. J. Pharm. Chem., 2: 236-240.

  35. Sreenivasulu, V., K.N. Jayaveera and P.M. Rao, 2009. Solid-state fermentation for the production of l-asparaginase by Aspergillus Sp. Res. J. Pharm. Phytochem., 1: 21-25.
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  36. Sreenivasulu, V., K.N. Jayaveera and P.M. Rao, 2009. Optimization of process parameters for the production of L-asparaginase from an isolated fungus. Res. J. Pharm. Phytochem., 1: 30-34.
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  37. Siddaiah, M., K.N. Jayavcera, R.P. Mallikarjuna, R.K. Ravindra, K.Y. Yasodha and R.G. Narender, 2009. Phytochemical screening and analgesic activity of methanolic extract of Ximenia americana. J. Pharm. Chem., 3: 23-25.

  38. Munna, S., K.N. Jayaveera and PM. Rao, 2009. Phytochemical screening and antimicrobial activity of alcohol extracts from leaf and bark of Ficus mollis. J. Pharm. Chem., 3: 48-50.

  39. Mai, C.W., S.Y. Wong, E.L. Tan, M.K. Balijepalli and M.R. Pichika, 2009. Antiproliferative and apoptotic studies of the standardised extracts of Etlingera elatior on human colorectal carcinoma cells. Malays. J. Chem., 11: 136-142.
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  40. Mai, C.W., P. Pakirisamy, E.F. Tay, S. Subramaniam, Z.H. Shamsuddin and M.R. Pichika, 2009. Nasopharyngeal Carcinoma cell proliferation and apoptosis induced by the standardised ethanolic extracts of Mucuna bracteata. Mal. J. Chem., 11: 143-148.
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  41. Adinarayana, K., K.N. Jayaveera, B.M. Katyayani and P.M. Rao, 2009. Growth inhibition and induction of apoptosis in estrogen receptor-positive and negative human breast carcinoma cells lines by Tephrosia calophylla. J. Pharm. Chem., 3: 137-143.

  42. Rao, P.M., V.D. Nadarajah, H.M. Er, B.C. Yiap and M.K. Fee et al., 2008. Antioxidant, chemopreventive and antiproliferative activities Malayisan Zingiber officinale variants. Planta Med., 74: 337-339.

  43. Jayaveera, K.N., V. Sreenivasulu, P.M. Rao and T. Bharathi, 2008. Screening of antitumour L-asparaginase positive fungal cultures from soil. J. Pharm. Chem., 2: 94-96.

  44. Sudhakar, M., C.V. Rao, P.M. Rao, D.B. Raju and Y. Venkateswarlu, 2006. Antimicrobial activity of Caesalpinia pulcherrima, Euphorbia hirta and Asystasia gangeticum. Fitoterapia, 77: 378-380.
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  45. Sudhakar, M., C.V. Rao, P.M. Rao and D.B. Raju, 2006. Evaluation of antimicrobial activity of Cleome viscosa and Gmelina asiatica. Fitoterapia, 77: 47-49.
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  46. Sudhakar, M., C.V. Rao, A.L. Rao, A. Ramesh, N. Srinivas, D.B. Raju and B.K. Murthy, 2004. Antinociceptive and anti-inflammatory effects of the standardized oil of Indian Callistemon lanceolatus leaves in experimental animals. East Central Afr. J. Pharm. Sci., 7: 10-15.
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  47. Devi, P.A., P.M. Rao, K.M.M. Krishna Prasad and C.S.P. Sastry, 2003. Four simple spectrophotometric methods of determination of lisinopril in pure state and in tablets. Indian J. Pharm. Sci., 65: 296-299.

  48. Rao, P.M., A.P. Devi, P.K. Krishna and C.S.P. Sastry, 2002. A note on the estimation of clomiphene citrate and pimozide in bulk forms and pharmaceutical formulations by precipitation reagents. Indian Drugs, 39: 395-397.

  49. Katyayani, B.M., P.M. Rao, G. Muralichand, D.S. Rao and T. Satyanarayana, 2002. Antimicrobial activity of bark of Alangium salvifoloium Linn. F. Indian J. Microbiol., 42: 87-89.

  50. Madhu, K.B., P. Rao Mallikarjuna, P. Balakrishna, T. Vedavathi and T. Satyanarayana, 2001. Antimicrobial potential of Gmelina asiatica leaves and Bauhinia Vahlii pods. Indian Drugs-Bombay, 38: 299-302.

  51. Mallikarjuna, P., V.U. Maheswara Rao and T. Satyanarayana, 1999. Antimicrobial activity of Zanthoxylum limonella stem. Indian Drugs, 36: 476-478.

  52. Rao, R.K., R. Jena and P.M. Rao, 1997. Studies on hepatoprotective activity of Vitex leucoxylon L. Ancient Sci. Life, 17: 128-134.

  53. Rao, R.K., G.P.M. Rao and B.G. Rao, 1997. Anti-inflammatory activity of the leaves and bark of Delonix elata. Ancient Sci. Life, 17: 141-143.
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