Dr. Ratan Singh Ray
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Dr. Ratan Singh Ray

Head
Indian Institute Of Toxicology Research, India

Highest Degree
Ph.D. in Chemistry from Kumaon University, India

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Area of Interest:

Biomedical Sciences
100%
Chemistry
62%
Zoology
90%
Botany
75%
Photobiology
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Yadav, N., A. Dwivedi, S.F. Mujtaba, A. Verma, R. Chaturvedi, R.S. Ray and G. Singh, 2014. Photosensitized mefloquine induces ROS-mediated DNA damage and apoptosis in keratinocytes under ambient UVB and sunlight exposure. Cell Biol. Toxicol., 30: 253-268.
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  2. Tripathi, A.K., A. Dwivedi, M.K. Pal, N. Rastogi and P. Gupta et al., 2014. Attenuated neuroprotective effect of riboflavin under UV-B irradiation via miR-203/c-Jun signaling pathway in vivo and in vitro. J. Biomed. Sci., Vol. 21. 10.1186/1423-0127-21-39.
    CrossRef  |  Direct Link  |  
  3. Dwivedi, A., S.F. Mujtaba, N. Yadav, H.N. Kushwaha and S.K. Amar et al., 2014. Cellular and molecular mechanism of ofloxacin induced apoptotic cell death under ambient UV-A and sunlight exposure. Free Radical Res., 48: 333-346.
    CrossRef  |  Direct Link  |  
  4. Yadav, N., A. Dwivedi, S.F. Mujtaba, H.N. Kushwaha, S.K. Singh and R.S. Ray, 2013. Ambient UVA‐induced expression of p53 and apoptosis in human skin melanoma A375 cell line by quinine. Photochem. Photobiol., 89: 655-664.
    CrossRef  |  Direct Link  |  
  5. Ray, R.S., S.F. Mujtaba, A. Dwivedi, N. Yadav and A. Verma et al., 2013. Singlet oxygen mediated DNA damage induced phototoxicity by ketoprofen resulting in mitochondrial depolarization and lysosomal destabilization. Toxicology, 314: 229-237.
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  6. Mujtaba, S.F., A. Dwivedi, N. Yadav, R.S. Ray and G. Singh, 2013. Singlet oxygen mediated apoptosis by anthrone involving lysosomes and mitochondria at ambient UV exposure. J. Hazard. Mater., 252: 258-271.
    CrossRef  |  Direct Link  |  
  7. Dwivedi, A., M.K. Pal, A.K. Tripathi, N. Yadav and S.F. Mujtaba et al., 2013. Role of type-II pathway in apoptotic cell death induction by photosensitized CDRI-97/78 under ambient exposure of UV-B. Toxicol. Lett., 222: 122-131.
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  8. Dwivedi, A., S.F. Mujtaba, H.N. Kushwaha, D. Ali, N. Yadav, S.K. Singh and R.S. Ray, 2012. Photosensitizing mechanism and identification of levofloxacin photoproducts at ambient UV radiation. Photochem. Photobiol., 88: 344-355.
    CrossRef  |  Direct Link  |  
  9. Verma, A., D. Ali, M. Farooq, A.B. Pant, R.S. Ray and R.K. Hans, 2011. Expression and inducibility of endosulfan metabolizing gene in Rhodococcus strain isolated from earthworm gut microflora for its application in bioremediation. Bioresour. Technol., 102: 2979-2984.
    CrossRef  |  Direct Link  |  
  10. Tobit, V., O.P. Verma, P.W. Ramteke and R.S. Ray, 2011. Phototoxic assessment of polycyclic aromatic hydrocarbons by using NIH-3T3 and L-929 cell lines. J. Aids Clinic. Res., Vol. 2. 10.4172/2155-6113.1000123.
    CrossRef  |  
  11. Mujtaba, S.F., A. Dwivedi, M.K.R. Mudiam, D. Ali, N. Yadav and R.S. Ray, 2011. Production of ROS by photosensitized anthracene under sunlight and UV‐R at ambient environmental intensities. Photochem. Photobiol., 87: 1067-1076.
    CrossRef  |  Direct Link  |  
  12. Ali, D., A. Verma, F. Mujtaba, A. Dwivedi, R.K. Hans and R.S. Ray, 2011. UVB-induced apoptosis and DNA damaging potential of chrysene via reactive oxygen species in human keratinocytes. Toxicol. Lett., 204: 199-207.
    CrossRef  |  Direct Link  |  
  13. Ali, D., R.S. Ray and R.K. Hans, 2010. UVA-induced cyototoxicity and DNA damaging potential of benz (e) acephenanthrylene. Toxicol. Lett., 199: 193-200.
    CrossRef  |  Direct Link  |  
  14. Roy, P., N. Kalra, N. Nigam, J. George and R.S. Ray et al., 2009. Resveratrol enhances ultraviolet B-induced cell death through nuclear factor-κB pathway in human epidermoid carcinoma A431 cells. Biochem. Biophys. Res. Commun., 384: 215-220.
    CrossRef  |  Direct Link  |  
  15. Ray, R.S., N. Agrawal and R.K. Hans, 2008. Use of L-929 cell line for sensitivity to UV radiation. Toxicol. In Vitro, 22: 1775-1781.
  16. Hans, R.K., N. Agrawal, K. Verma, R.B. Misra, R.S. Ray and M. Farooq, 2008. Assessment of the phototoxic potential of cosmetic products. Food Chem. Toxicol., 46: 1653-1658.
    CrossRef  |  Direct Link  |  
  17. Agrawal, N., R.S. Ray, M. Farooq, A.B. Pant and R.K. Hans, 2007. Photosensitizing potential of ciprofloxacin at ambient level of UV radiation. Photochem. Photobiol., 83: 1226-1236.
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  18. Ray, R.S., N. Agrawal, R.B. Misra, M. Farooq and R.K. Hans, 2006. Radiation-induced in vitro phototoxic potential of some fluoroquinolones. Drug Chem. Toxicol., 29: 25-38.
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  19. Misra, R.B., R.S. Ray and R.K. Hans, 2005. Effect of UVB radiation on human erythrocytes in vitro. Toxicol. In Vitro, 19: 433-438.
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  20. Farooq, M., U. Shankar, R.S. Ray, R.B. Misra, N. Agrawal, K. Verma and R.K. Hans, 2005. Morphological and metabolic alterations in duckweed (Spirodela polyrhiza) on long-term low-level chronic UV-B exposure. Ecotoxicol. Environ. Safety, 62: 408-414.
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  21. Babu, G.S., M. Farooq, R.S. Ray, P.C. Joshi, P.N. Viswanathan and R.K. Hans, 2003. DDT and HCH residues in basmati rice (Oryza sativa) cultivated in Dehradun (India). Water Air Soil Pollut., 144: 149-157.
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  22. Ray, R.S., S.K. Singh, R.K. Hans and P.C. Joshi, 2002. Identification of new photoreduction products of pentachlorophenol. J. Environ. Monit., 4: 449-451.
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  23. Ray, R.S., R.B. Misra, M. Farooq and R.K. Hans, 2002. Effect of UV-B radiation on some common antibiotics. Toxicol. In Vitro, 16: 123-127.
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  24. Pandey, R., S. Mehrotra, R.S. Ray, P.C. Joshi and R.K. Hans, 2002. Evaluation of UV-radiation induced singlet oxygen generation potential of selected drugs. Drug Chem. Toxicol., 25: 215-225.
    CrossRef  |  Direct Link  |  
  25. Misra, R.B., G.S. Babu, R.S. Ray and R.K. Hans, 2002. Tubifex: A sensitive model for UV-B-induced phototoxicity. Ecotoxicol. Environ. Safety, 52: 288-295.
    CrossRef  |  Direct Link  |  
  26. Ray, R.S., S. Mehrotra, U. Shankar, G.S. Babu, P.C. Joshi and R.K. Hans, 2001. Evaluation of UV-induced superoxide radical generation potential of some common antibiotics. Drug Chem. Toxicol., 24: 191-200.
    CrossRef  |  Direct Link  |  
  27. Farooq, M., G.S. Babu, R.S. Ray, R.B. Misra, U. Shankar and R.K. Hans, 2000. Sensitivity of duckweed (Lemna major) to ultraviolet-B radiation. Biochem. Biophys. Res. Commun., 276: 970-973.
    CrossRef  |  Direct Link  |  
  28. Ray, R.S., S. Mehrotra, S. Prakash and P.C. Joshi, 1996. Ultraviolet radiation-induced production of superoxide radicals by selected antibiotics. Drug Chem. Toxicol., 19: 121-130.
    CrossRef  |  Direct Link  |  
  29. Joshi, P.C., G.S. Babu, U. Shankar, K.R. Arya and R.S. Ray et al., 1996. Ultraviolet radiation measurement and physiological changes in some C3, C4 plants and algae during a total solar eclipse. Dermatologia Cosmetica, 4: 186-190.