Dr. Mohammad  Athar

Dr. Mohammad Athar

Professor
University of Alabama at Birmingham, USA


Highest Degree
Ph.D. in Chemistry from Aligarh Muslim University, India

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Area of Interest:

Chemistry
100%
Food and Chemical Toxicology
62%
Photochemistry
90%
Photobiology
75%
Anticancer Research
55%

Education

1980

Ph.D.

Aligarh Muslim University, India

Chemistry

Selected Publications

  1. Srivastava, R.K., C. Li, S.C. Chaudhary, M.E. Ballestas and C.A. Elmets et al., 2013. Unfolded protein response (UPR) signaling regulates arsenic trioxide-mediated macrophage innate immune function disruption. Toxicol. Applied Pharmacol., 272: 879-887.
    CrossRef  |  

  2. Pal, H.C., S. Sharma, L.R. Strickland, J. Agarwal and M. Athar et al., 2013. Delphinidin reduces cell proliferation and induces apoptosis of non-small-cell lung cancer cells by targeting EGFR/VEGFR2 signaling pathways. PloS One, Vol. 8. 10.1371/journal.pone.0077270.
    CrossRef  |  

  3. Pal, H.C., S. Sharma, C.A. Elmets, M. Athar and F. Afaq, 2013. Fisetin inhibits growth, induces G2/M arrest and apoptosis of human epidermoid carcinoma A431 cells: Role of mitochondrial membrane potential disruption and consequent caspases activation. Exp. Dermatol., 22 470.
    CrossRef  |  ASCI  |  PubMed  |  

  4. Li, C., Z. Weng, S.F. Doran, R.K. Srivastava, F. Afaq, S. Matalon and M. Athar, 2013. Chlorine induces the unfolded protein response in murine lungs and skin. Am. J. Respiratory Cell Mol. Biol., 49: 197-203.
    CrossRef  |  Direct Link  |  

  5. Li, C., R.K. Srivastava, C.A. Elmets, F. Afaq and M. Athar, 2013. Arsenic-induced cutaneous hyperplastic lesions are associated with the dysregulation of Yap, a Hippo signaling-related protein. Biochem. Biophys. Res. Commun., 438: 607-612.
    CrossRef  |  

  6. Kurundkar, D., R.K. Srivastava, S.C. Chaudhary, M.E. Ballestas, L. Kopelovich, C.A. Elmets and M. Athar, 2013. Vorinostat, an HDAC inhibitor attenuates epidermoid squamous cell carcinoma growth by dampening mTOR signaling pathway in a human xenograft murine model. Toxicol. Applied Pharmacol., 266: 233-244.
    CrossRef  |  

  7. Kaylani, S.Z., J. Xu, R.K. Srivastava, L. Kopelovich, J.G. Pressey and M. Athar, 2013. Rapamycin targeting mTOR and hedgehog signaling pathways blocks human rhabdomyosarcoma growth in xenograft murine model. Biochem. Biophys. Res. Commun., 435: 557-561.
    CrossRef  |  

  8. Chaudhary, S.C., M.S. Siddiqui, M. Athar and M.S. Alam, 2013. Geraniol inhibits murine skin tumorigenesis by modulating COX‐2 expression, Ras‐ERK1/2 signaling pathway and apoptosis. J. Applied Toxicol., 33: 828-835.
    CrossRef  |  

  9. Arumugam, A., Z. Weng, S.S. Talwelkar, S.C. Chaudhary and L. Kopelovich et al., 2013. Inhibiting cycloxygenase and ornithine decarboxylase by diclofenac and alpha-difluoromethylornithine blocks cutaneous SCCs by targeting Akt-ERK axis. PloS One, Vol. 8. 10.1371/journal.pone.0080076.
    CrossRef  |  

  10. Singh, T., S.C. Chaudhary, P. Kapur, Z. Weng, C.A. Elmets, L. Kopelovich and M. Athar, 2012. Nitric oxide donor exisulind is an effective inhibitor of murine photocarcinogenesis. Photochem. Photobiol., 88: 1141-1148.
    CrossRef  |  

  11. Kim, H., A. Casta, X. Tang, C.T. Luke and A.L. Kim et al., 2012. Loss of hairless confers susceptibility to UVB-induced tumorigenesis via disruption of NF-kappaB signaling. PloS One, Vol. 7. 10.1371/journal.pone.0039691.
    CrossRef  |  

  12. He, D., H. Li, N. Yusuf, C.A. Elmets, M. Athar, S.K. Katiyar and H. Xu, 2012. IL-17 mediated inflammation promotes tumor growth and progression in the skin. PloS One, Vol. 7. 10.1371/journal.pone.0032126.
    CrossRef  |  

  13. Chaudhary, S.C., T. Singh, P. Kapur, Z. Weng and A. Arumugam et al., 2012. Nitric oxide-releasing sulindac is a novel skin cancer chemopreventive agent for UVB-induced photocarcinogenesis. Toxicol. Applied Pharmacol., 268: 249-255.
    CrossRef  |  

  14. Chaudhary, S.C., M.S. Siddiqui, M. Athar and M.S. Alam, 2012. D-Limonene modulates inflammation, oxidative stress and Ras-ERK pathway to inhibit murine skin tumorigenesis. Human Exp. Toxicol., 31: 798-811.
    CrossRef  |  Direct Link  |  

  15. Chaudhary, S.C., D. Kurundkar, C.A. Elmets, L. Kopelovich and M. Athar, 2012. Metformin, an antidiabetic agent reduces growth of cutaneous squamous cell carcinoma by targeting mTOR signaling pathway. Photochem. Photobiol., 88: 1149-1156.
    CrossRef  |  PubMed  |  Direct Link  |  

  16. Arumugam, A., S.B. Walsh, J. Xu, F. Afaq, C.A. Elmets and M. Athar, 2012. Combined inhibition of p38 and Akt signaling pathways abrogates cyclosporine A-mediated pathogenesis of aggressive skin SCCs. Biochem. Biophys. Res. Commun., 425: 177-181.
    CrossRef  |  

  17. Xu, J., S.B. Walsh, Z.M. Verney, L. Kopelovich, C.A. Elmets and M. Athar, 2011. Procarcinogenic effects of cyclosporine A are mediated through the activation of TAK1/TAB1 signaling pathway. Biochem. Biophys. Res. Commun., 408: 363-368.
    CrossRef  |  

  18. Walsh, S.B., J. Xu, H. Xu, A.R. Kurundkar and A. Maheshwari et al., 2011. Cyclosporine a mediates pathogenesis of aggressive cutaneous squamous cell carcinoma by augmenting epithelial‐mesenchymal transition: Role of TGFβ signaling pathway. Mol. Carcinogenesis, 50: 516-527.
    CrossRef  |  

  19. Maheshwari, A., D.R. Kelly, T. Nicola, N. Ambalavanan and S.K. Jain et al., 2011. TGF-β 2 suppresses macrophage cytokine production and mucosal inflammatory responses in the developing intestine. Gastroenterology, 140: 242-253.
    CrossRef  |  Direct Link  |  

  20. Li, C., J. Xu, F. Li, S.C. Chaudhary and Z. Weng et al., 2011. Unfolded protein response signaling and MAP kinase pathways underlie pathogenesis of arsenic-induced cutaneous inflammation. Cancer Prevention Res., 4: 2101-2109.
    CrossRef  |  Direct Link  |  

  21. Croyle, M.J., J.M. Lehman, A.K. O'Connor, S.Y. Wong and E.B. Malarkey et al., 2011. Role of epidermal primary cilia in the homeostasis of skin and hair follicles. Development, 138: 1675-1685.
    CrossRef  |  

  22. Byekova, Y.A., J.L. Herrmann, J. Xu, C.A. Elmets and M. Athar, 2011. Liver kinase B1 (LKB1) in the pathogenesis of UVB-induced murine basal cell carcinoma. Arch. Biochem. Biophys., 508: 204-211.
    CrossRef  |  

  23. Back, J.H., H.R. Rezvani, Y. Zhu, V. Guyonnet-Duperat, M. Athar, D. Ratner and A.L. Kim, 2011. Cancer cell survival following DNA damage-mediated premature senescence is regulated by mammalian target of rapamycin (mTOR)-dependent Inhibition of sirtuin 1. J. Biol. Chem., 286: 19100-19108.
    CrossRef  |  

  24. Xu, J., L. Timares, C. Heilpern, Z. Weng and C. Li et al., 2010. Targeting wild-type and mutant p53 with small molecule CP-31398 blocks the growth of rhabdomyosarcoma by inducing reactive oxygen species-dependent apoptosis. Cancer Res., 70: 6566-6576.
    CrossRef  |  

  25. Tang, J.Y., M. Aszterbaum, M. Athar, F. Barsanti and C. Cappola et al., 2010. Basal cell carcinoma chemoprevention with nonsteroidal anti-inflammatory drugs in genetically predisposed PTCH1+/−humans and mice. Cancer Prevention Res., 3: 25-34.
    CrossRef  |  

  26. Kim, K.H., J.H. Back, Y. Zhu, J. Arbesman and M. Athar et al., 2010. Resveratrol targets transforming growth factor-β2 signaling to block UV-induced tumor progression. J. Investigative Dermatol., 131: 195-202.
    CrossRef  |  Direct Link  |  

  27. Kaur, G., M. Athar and M.S. Alam, 2010. Dietary supplementation of silymarin protects against chemically induced nephrotoxicity, inflammation and renal tumor promotion response. Investigational New Drugs, 28: 703-713.
    CrossRef  |  Direct Link  |  

  28. Kaur, G., M. Athar and M.S. Alam, 2010. Eugenol precludes cutaneous chemical carcinogenesis in mouse by preventing oxidative stress and inflammation and by inducing apoptosis. Mol. Carcinog., 49: 290-301.
    CrossRef  |  

  29. Shaik, S.S., T.D. Soltau, G. Chaturvedi, B. Totapally and J.S. Hagood et al., 2009. Low intensity shear stress increases endothelial ELR+ CXC chemokine production via a focal adhesion kinase-p38β MAPK-NF-κB pathway. J. Biol. Chem., 284: 5945-5955.
    CrossRef  |  

  30. Kaur, G., M.S. Alam and M. Athar, 2009. Cumene hydroperoxide debilitates macrophage physiology by inducing oxidative stress: Possible protection by alpha-tocopherol. Chem.-Biol. Interact., 179: 94-102.
    CrossRef  |  

  31. Kaur, G., I.A. Lone, M. Athar and S.M. Alam, 2009. Guilandina bonduc L. possesses antioxidant activity and precludes ferric nitrilotriacetate (Fe-NTA) induced renal toxicity and tumor promotion response. J. Environ. Pathol. Toxicol. Oncol., 28: 163-175.
    CrossRef  |  

  32. Chaudhary, S.C., M.S. Alam, M.S. Siddiqui and M. Athar, 2009. Perillyl alcohol attenuates Ras-ERK signaling to inhibit murine skin inflammation and tumorigenesis. Chem.-Biol. Interactions, 179: 145-153.
    CrossRef  |  

  33. Chaudhary, S.C., M.S. Alam, M.S. Siddiqui and M. Athar, 2009. Chemopreventive effect of farnesol on DMBA/TPA-induced skin tumorigenesis: Involvement of inflammation, Ras-ERK pathway and apoptosis. Life Sci., 85: 196-205.
    CrossRef  |  

  34. Tang, X., A.L. Kim, L. Kopelovich, D.R. Bickers and M. Athar, 2008. Cyclooxygenase-2 inhibitor nimesulide blocks ultraviolet B-induced photocarcinogenesis in SKH-1 hairless mice. Photochem. Photobiol., 84: 522-527.
    CrossRef  |  

  35. Rahman, S., K. Bhatia, A.Q. Khan, M. Kaur and F. Ahmad et al., 2008. Topically applied vitamin E prevents massive cutaneous inflammatory and oxidative stress responses induced by double application of 12-O-tetradecanoylphorbol-13-acetate (TPA) in mice. Chemico-Biol. Interactions, 172: 195-205.
    CrossRef  |  

  36. Pradhan, S., H.K. Kim, C.J. Thrash, M.A. Cox and S.K. Mantena et al., 2008. A critical role for the proapoptotic protein bid in ultraviolet-induced immune suppression and cutaneous apoptosis. J. Immunol., 181: 3077-3088.
    Direct Link  |  

  37. Lebedeva, I.V., Z.Z. Su, N. Vozhilla, L. Chatman and D. Sarkar et al., 2008. Mechanism of In vitro pancreatic cancer cell growth inhibition by melanoma differentiation-associated gene-7/Interleukin-24 and perillyl alcohol. Cancer Res., 68: 7439-7447.
    CrossRef  |  Direct Link  |  

  38. Lebedeva, I.V., Z.Z. Su, N. Vozhilla, L. Chatman and D. Sarkar et al., 2008. Chemoprevention by perillyl alcohol coupled with viral gene therapy reduces pancreatic cancer pathogenesis. Mol. Cancer Ther., 7: 2042-2050.
    CrossRef  |  

  39. Kim, H.K., H. Zhang, H. Li, T.T. Wu and S. Swisher et al., 2008. Slit2 inhibits the growth and metastasis of fibrosarcoma and squamous cell carcinoma. Neoplasia, 10: 1411-1420.
    Direct Link  |  

  40. Kaur, G., M. Athar and M.S. Alam, 2008. Quercus infectoria galls possess antioxidant activity and abrogates oxidative stress-induced functional alterations in murine macrophages. Chem. Biol. Interact., 171: 272-282.
    CrossRef  |  

  41. Alam, M.S., G. Kaur, A. Ali, H. Hamid, M. Ali and M. Athar, 2008. Two new bioactive oleanane triterpene glycosides from Terminalia arjuna. Nat. Prod. Res., 22: 1279-1288.
    CrossRef  |  PubMed  |  Direct Link  |  

  42. Tang, X., Y. Zhu, L. Han, A.L. Kim, L. Kopelovich, D.R. Bickers and M. Athar, 2007. CP-31398 restores mutant p53 tumor suppressor function and inhibits UVB-induced skin carcinogenesis in mice. J. Clin. Investigation, 117: 3753-3764.
    CrossRef  |  Direct Link  |  

  43. Sultana, Y., K. Kohli, M. Athar, R.K. Khar and M. Aqil, 2007. Effect of pre‐treatment of almond oil on ultraviolet B-induced cutaneous photoaging in mice. J. Cosmetic Dermatol., 6: 14-19.
    CrossRef  |  

  44. Sarwar, A.M., G. Kaur, Z. Jabbar, K. Javed and M. Athar, 2007. Eruca sativa seeds possess antioxidant activity and exert a protective effect on mercuric chloride induced renal toxicity. Food Chem. Toxicol., 45: 910-920.
    CrossRef  |  

  45. Lone, I.A., G. Kaur, M. Athar and M.S. Alam, 2007. Protective effect of Rumex patientia (English Spinach) roots on ferric nitrilotriacetate (Fe-NTA) induced hepatic oxidative stress and tumor promotion response. Food Chem. Toxiol., 45: 1821-1829.
    CrossRef  |  Direct Link  |  

  46. Kaur, G., I.A. Lone, M. Athar and M.S. Alam, 2007. Protective effect of Didymocarpus pedicellata on ferric nitrilotriacetate (Fe-NTA) induced renal oxidative stress and hyperproliferative response. Chem.-Biol. Interactions, 165: 33-44.
    CrossRef  |  

  47. Arif, E., A. Vibhuti, P. Alam, D. Deepak, B. Singh, M. Athar and M.A. Pasha, 2007. Association of CYP2E1 and NAT2 gene polymorphisms with chronic obstructive pulmonary disease. Clin. Chim. Acta, 382: 37-42.
    CrossRef  |  Direct Link  |  

  48. Arif, E., A. Ahsan, A. Vibhuti, C. Rajput and D. Deepak et al., 2007. Endothelial nitric oxide synthase gene variants contribute to oxidative stress in COPD. Biochem. Biophys. Res. Commun., 361: 182-188.
    CrossRef  |  Direct Link  |  

  49. Agarwal, M.K., M. Iqbal and M. Athar, 2007. Garlic oil ameliorates ferric nitrilotriacetate (Fe-NTA)-induced damage and tumor promotion: Implications for cancer prevention. Food Chem. Toxicol., 45: 1634-1640.
    CrossRef  |  

  50. Parvez, S., H. Tabassum, H. Rehman, B.D. Banerjee, M. Athar and S. Raisuddin, 2006. Catechin prevents tamoxifen-induced oxidative stress and biochemical perturbations in mice. Toxicology, 225: 109-118.
    CrossRef  |  PubMed  |  Direct Link  |  

  51. Lebedeva, I.V., D. Sarkar, Z.Z. Su, R.V. Gopalkrishnan and M. Athar et al., 2006. Molecular target-based therapy of pancreatic cancer. Cancer Res., 66: 2403-2413.
    CrossRef  |  

  52. Kim, A.L., Y. Zhu, H. Zhu, L. Han, L. Kopelovich, D.R. Bickers and M. Athar, 2006. Resveratrol inhibits proliferation of human epidermoid carcinoma A431 cells by modulating MEK1 and AP‐1 signalling pathways. Exp. Dermatol., 15: 538-546.
    CrossRef  |  Direct Link  |  

  53. Khan, B., S.F. Ahmad, S. Bani, A. Kaul and K.A. Suri et al., 2006. Augmentation and proliferation of T lymphocytes and Th-1 cytokines by Withania somnifera in stressed mice. Int. Immunopharmacol., 6: 1394-1403.
    CrossRef  |  PubMed  |  Direct Link  |  

  54. Kaur, G., Z. Jabbar, M. Athar and M.S. Alam, 2006. Punica granatum (pomegranate) flower extract possesses potent antioxidant activity and abrogates Fe-NTA induced hepatotoxicity in mice. Food Chem. Toxicol., 44: 984-993.
    CrossRef  |  Direct Link  |  

  55. Kaur, G., M.S. Alam, Z. Jabbar, K. Javed and M. Athar, 2006. Evaluation of antioxidant activity of Cassia siamea flowers. J. Ethnopharmacol., 108: 340-348.
    CrossRef  |  Direct Link  |  

  56. Alam, M.S., G. Kaur, Z. Jabbar, K. Javed and M. Athar, 2006. Evaluation of antioxidant activity of Salix caprea flowers. Phytother. Res., 20: 479-483.
    CrossRef  |  

  57. Paul, B., C.S. Hayes, A. Kim, M. Athar and S.K. Gilmour, 2005. Elevated polyamines lead to selective induction of apoptosis and inhibition of tumorigenesis by (−)-epigallocatechin-3-gallate (EGCG) in ODC/Ras transgenic mice. Carcinogenesis, 26: 119-124.
    CrossRef  |  Direct Link  |  

  58. Liu, S.X., M.M. Davidson, X. Tang, W.F. Walker, M. Athar, V. Ivanov and T.K. Hei, 2005. Mitochondrial damage mediates genotoxicity of arsenic in mammalian cells. Cancer Res., 65: 3236-3242.
    CrossRef  |  PubMed  |  

  59. Lee, J.L., A. Kim, L. Kopelovich, D.R. Bickers and M. Athar, 2005. Differential expression of E prostanoid receptors in murine and human non-melanoma skin cancer. J. Investigative Dermatol., 125: 818-825.
    CrossRef  |  Direct Link  |  

  60. Kim, A.L., J.M. Labasi, Y. Zhu, X. Tang and K. McClure et al., 2005. Role of p38 MAPK in UVB-induced inflammatory responses in the skin of SKH-1 hairless mice. J. Investigative Dermatol., 124: 1318-1325.
    CrossRef  |  

  61. Hamid, H., G. Kaur, S.T. Abdullah, M. Ali, M. Athar and M.S. Alam, 2005. Two new compounds from the galls of quercus infectoria. with nitric oxide and superoxide inhibiting ability. Pharm. Biol., 43: 317-323.
    Direct Link  |  

  62. Agarwal, M.K., M. Iqbal and M. Athar, 2005. Vitamin E inhibits hepatic oxidative stress, toxicity and hyperproliferation in rats treated with the renal carcinogen ferric nitrilotriacetate. Redox Rep., 10: 62-70.
    PubMed  |  Direct Link  |  

  63. Agarwal, M.K., M. Iqbal and M. Athar, 2005. Inhibitory effect of 18beta-glycyrrhetinic acid on 12-O-tetradecanoyl phorbol-13-acetate-induced cutaneous oxidative stress and tumor promotion in mice. Redox Rep., 10: 151-157.
    PubMed  |  Direct Link  |  

  64. Yamamoto, T., J. Lewis, J. Wataha, D. Dickinson and B. Singh et al., 2004. Roles of catalase and hydrogen peroxide in green tea polyphenol-induced chemopreventive effects. J. Pharmacol. Exp. Ther., 308: 317-323.
    CrossRef  |  

  65. Vogt, A., P.T. Chuang, J. Hebert, J. Hwang and Y. Lu et al., 2004. Immunoprevention of basal cell carcinomas with recombinant hedgehog-interacting protein. J. Exp. Med., 199: 753-761.
    CrossRef  |  Direct Link  |  

  66. Tang, X., A.L. Kim, D.J. Feith, A.E. Pegg and J. Russo et al., 2004. Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/-mice. J. Clin. Investigation, 113: 867-875.
    CrossRef  |  

  67. So, P.L., K. Lee, J. Hebert, P. Walker and Y. Lu et al., 2004. Topical tazarotene chemoprevention reduces basal cell carcinoma number and size in Ptch1+/− mice exposed to ultraviolet or ionizing radiation. Cancer Res., 64: 4385-4389.
    CrossRef  |  Direct Link  |  

  68. Kaur, G., M. Sarwar Alam and M. Athar, 2004. Nimbidin suppresses functions of macrophages and neutrophils: Relevance to its antiinflammatory mechanisms. Phytotherapy Res., 18: 419-424.
    CrossRef  |  

  69. Kaur, G., H. Hamid, A. Ali, M.S. Alam and M. Athar, 2004. Antiinflammatory evaluation of alcoholic extract of galls of Quercus infectoria. J. Ethnopharmacol., 90: 285-292.
    CrossRef  |  Direct Link  |  

  70. Bhasin, G., H. Kauser and M. Athar, 2004. Low iron diet retards 12-O-tetradecanoyl phorbol-13-acetate-mediated tumor promotion in murine skin. Arch. Toxicol., 78: 283-289.
    CrossRef  |  

  71. Bhasin, G., H. Kauser and M. Athar, 2004. Free radical generating agents lead to the rapid progression of benign skin tumors to carcinoma in iron-overloaded mice. Arch. Toxicol., 78: 139-146.
    CrossRef  |  

  72. Athar, M., K.P. An, X. Tang, K.D. Morel, A.L. Kim, L. Kopelovich and D.R. Bickers, 2004. Photoprotective effects of sulindac against ultraviolet B-induced phototoxicity in the skin of SKH-1 hairless mice. Toxicol. Applied Pharmacol., 195: 370-378.
    CrossRef  |  

  73. Athar, M., C. Li, X. Tang, S. Chi and X. Zhang et al., 2004. Inhibition of smoothened signaling prevents ultraviolet B-induced basal cell carcinomas through regulation of Fas expression and apoptosis. Cancer Res., 64: 7545-7552.
    CrossRef  |  Direct Link  |  

  74. Agarwal, M.K., M.L. Agarwal, M. Athar and S. Gupta, 2004. Tocotrienol-rich fraction of palm oil activates p53, modulates Bax/Bcl2 ratio and induces apoptosis independent of cell cycle association. Cell Cycle, 3: 205-211.
    Direct Link  |  

  75. Sahdev, S., T.K. Taneja, M. Mohan, N.K. Sah, A.K. Khar, S.E. Hasnain and M. Athar, 2003. Baculoviral p35 inhibits oxidant-induced activation of mitochondrial apoptotic pathway. Biochem. Biophys. Res. Commun., 307: 483-490.
    CrossRef  |  

  76. Rahman, A., S. Ahmed, S.M. Vasenwala and M. Athar, 2003. Glyceryl trinitrate, a nitric oxide donor, abrogates ferric nitrilotriacetate-induced oxidative stress and renal damage. Arch. Biochem. Biophys., 418: 71-79.
    CrossRef  |  

  77. Mohan, M., T.K. Taneja, S. Sahdev, K. Mohareer and R. Begum et al., 2003. Antioxidants prevent UV-induced apoptosis by inhibiting mitochondrial cytochrome c release and caspase activation in Spodoptera frugiperda (Sf9) cells. Cell Biol. Int., 27: 483-490.
    CrossRef  |  Direct Link  |  

  78. Kauser, H., G. Bhasin, M.A. Zargar and M. Athar, 2003. Palm oil alleviates 12-O-tetradecanoyl-phorbol-13-acetate-induced tumor promotion response in murine skin. Cancer Lett., 192: 151-160.
    CrossRef  |  PubMed  |  Direct Link  |  

  79. Hsu, S., J. Lewis, B. Singh, P. Schoenlein and T. Osaki et al., 2003. Green tea polyphenol targets the mitochondria in tumor cells inducing caspase 3-dependent apoptosis. Anticancer Res., 23: 1533-1539.
    PubMed  |  Direct Link  |  

  80. Bhasin, G., H. Kausar, M. Sarwar Alam and M. Athar, 2003. Progressive iron overload enhances chemically mediated tumor promotion in murine skin. Arch. Biochem. Biophys., 409: 262-273.
    CrossRef  |  

  81. Kim, A.L., M. Athar, D.R. Bickers and J. Gautier, 2002. Ultraviolet-B-induced G1 arrest is mediated by downregulation of cyclin-dependent kinase 4 in transformed keratinocytes lacking functional p53. J. Investigative Dermatol., 118: 818-824.
    CrossRef  |  

  82. Kim, A.L., M. Athar, D.R. Bickers and J. Gautier, 2002. Stage-specific alterations of cyclin expression during UVB-induced Murine skin tumor development. Photochem. Photobiol., 75: 58-67.
    CrossRef  |  

  83. Kim, A.L., J. Gautier, D.R. Bickers and M. Athar, 2002. Reduced cyclin D1 ubiquitination in UVB-induced murine squamous cell carcinomas. Biochem. Biophys. Res. Commun., 298: 377-382.
    CrossRef  |  Direct Link  |  

  84. Bhasin, G., H. Kauser and M. Athar, 2002. Protoporphyrin-IX accumulation and cutaneous tumor regression in mice using a ferrochelatase inhibitor. Cancer Lett., 187: 9-16.
    CrossRef  |  PubMed  |  

  85. Bhasin, G., H. Kauser and M. Athar, 2002. Low iron state is associated with reduced tumor promotion in a two-stage mouse skin carcinogenesis model. Food Chem. Toxicol., 40: 1105-1111.
    CrossRef  |  

  86. Bhasin, G., H. Kauser and M. Athar, 2002. Iron augments stage-I and stage-II tumor promotion in murine skin. Cancer Lett., 183: 113-122.
    CrossRef  |  

  87. An, K.P., M. Athar, X. Tang, S.K. Katiyar and J. Russo et al., 2002. Cyclooxygenase-2 expression in murine and human nonmelanoma skin cancers: Implications for therapeutic approaches. Photochem. Photobiol., 76: 73-80.
    CrossRef  |  PubMed  |  

  88. Trikha, P., N. Sharma and M. Athar, 2001. Nitroglycerin: A NO donor inhibits TPA-mediated tumor promotion in murine skin. Carcinogenesis, 22: 1207-1211.
    CrossRef  |  

  89. Sharma, N., P. Trikha, M. Athar and S. Raisuddin, 2001. Inhibition of benzo[a]pyrene- and cyclophoshamide-induced mutagenicity by Cinnamomum cassia. Mutat. Res., 480: 179-188.
    CrossRef  |  

  90. Rezazadeh, H., A.R. Nayebi and M. Athar, 2001. Role of iron-dextran on 7, 12-dimethylbenz (a) anthracene-initiated and croton oil-promoted cutaneous tumorigenesis in normal and pregnant mice. Human Exp. Toxicol., 20: 471-476.
    CrossRef  |  

  91. Liu, S.X., M. Athar, I. Lippai, C. Waldren and T.K. Hei, 2001. Induction of oxyradicals by arsenic: Implication for mechanism of genotoxicity. Proc. Natl. Acad. Sci. USA., 98: 1643-1648.
    CrossRef  |  Direct Link  |  

  92. Hsu, S., F.S. Yu, J. Lewis, B. Singh and J. Borke et al., 2001. Induction of p57 is required for cell survival when exposed to green tea polyphenols. Anticancer Res., 22: 4115-4120.
    PubMed  |  Direct Link  |  

  93. Hebert, J.L., F. Khugyani, M. Athar, L. Kopelovich, E.H. Epstein and M. Aszterbaum, 2001. Chemoprevention of basal cell carcinomas in the ptc1+/-mouse-green and black tea. Skin Pharmacol. Physiol., 14: 358-362.
    CrossRef  |  

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