Dr. Kutubuddin Ali Molla
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Dr. Kutubuddin Ali Molla

Research Scientist
National Rice Research Institute, India

Highest Degree
PostDoc Fellow in Biotechnology, Molecular Genetics from Pennsylvania State University, USA

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Biography

Dr. Kutubuddin Ali Molla is currently working as a Faculty Scientist at the National Rice Research Institute (formerly, Central Rice Research Institute), Cuttack, India. He recently completed his post-doctoral research at the Pennsylvania State University availing the prestigious Fulbright Fellowship (2017-2019). Dr. Molla extensively worked on CRISPR-Cas mediated conventional genome editing and precise editing using Base editing and HDR. He has won the INSA Young Scientist Medal-2020 from the Indian National Science Academy, New Delhi.

His area of expertise includes Precise Genome Editing, Genetic Engineering, Molecular Biology, Biotechnology, Agriculture, Plant, Tissue Culture, and Transgenic.

Dr. Molla's group is engaged in developing genome editing tools for plant and utilize them for crop improvement. The group focuses on base editing and prime editing tools. Any student having his/her own fellowship (CSIR/UGC-JRF fellowship/ DST Inspire/any other) may contact for pursuing research work under Dr. Molla's guidance.

Area of Interest:

Biology
100%

Research Publications in Numbers

Books
1
Chapters
2
Articles
25
Abstracts
0

Selected Publications

  1. Mushtaq, M., S. Mukhtar, A. Sakina, A.A. Dar and R. Bhat et al., 2020. Tweaking genome-editing approaches for virus interference in crop plants. Plant Physiol. Biochem., 147: 242-250.
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  2. Molla, K.A., Y. Qi, S. Karmakar and M.J. Baig, 2020. Base editing landscape extends to perform transversion mutation. Trends Genetics, 10.1016/j.tig.2020.09.001.
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  3. Molla, K.A., S. Karmakar, J. Molla, P. Bajaj, R.K. Varshney, S.K. Datta and K. Datta, 2020. Understanding sheath blight resistance in rice: the road behind and the road ahead. Plant Biotechnol. J., 18: 895-915.
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  4. Molla, K.A., S. Karmakar and M.T. Islam, 2020. Wide horizons of CRISPR-Cas-derived technologies for basic biology, agriculture, and medicine. In: CRISPR-Cas Methods, Molla, K.A., S. Karmakar and M.T. Islam, Springer, US, pp: 1-23.
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  5. Molla, K.A., J. Shih and Y. Yang, 2020. Single-nucleotide editing for zebra3 and wsl5 phenotypes in rice using CRISPR/Cas9-mediated adenine base editors. aBIOTECH, 1: 106-118.
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  6. Molla, K.A. and Y. Yang, 2020. Predicting CRISPR/Cas9-induced mutations for precise genome editing. Trends Biotechnol., 38: 136-141.
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  7. Molla, K.A. and Y. Yang, 2020. CRISPR-Cas-mediated single base editing at more than one locus in rice genome. In: CRISPR-Cas Methods, Islam, M.T., P.K. Bhowmik and K.A. Molla, Springer, U.S., 12.
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  8. Katara, J.L., R.L. Verma, M. Parida, U. Ngangkham and K.A. Molla et al., 2020. Differential expression of genes at panicle initiation and grain filling stages implied in heterosis of rice hybrids. Int. J. Mol. Sci., Vol. 21. 10.3390/ijms21031080.
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  9. Islam, M.T., P.K. Bhowmik and K.A. Molla, 2020. CRISPR-Cas Methods. Springer, New York, Pages: 278.
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  10. Chattopadhyay, K., S.K. Mohanty, J. Vijayan, B.C. Marndi and A. Sarkar et al., 2020. Genetic dissection of component traits for salinity tolerance at reproductive stage in rice. Plant Mol. Biol. Rep., 10.1007/s11105-020-01257-4.
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  11. Bal, A., P. Samal, M. Chakraborti, A.K. Mukherjee and S. Ray et al., 2020. Stable quantitative trait locus (QTL) for sheath blight resistance from rice cultivar CR 1014. Euphytica, 10.1007/s10681-020-02702-x.
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  12. Molla, K.A., T.P.M. Azharudheen, S. Ray, S. Sarkar and A. Swain, 2019. Novel biotic stress responsive candidate gene based SSR (cgSSR) markers from rice. Euphytica, Vol. 215. 10.1007/s10681-018-2329-6.
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  13. Molla, K.A. and Y. Yang, 2019. CRISPR/Cas-mediated base editing: technical considerations and practical applications. Trends Biotechnol., 37: 1121-1142.
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  14. Kuanar, S.R., K.A. Molla, K. Chattopadhyay, R.K. Sarkar and P.K. Mohapatra, 2019. Introgression of Sub1 (SUB1) QTL in mega rice cultivars increases ethylene production to the detriment of grain- filling under stagnant flooding. Sci. Rep., Vol. 9. 10.1038/s41598-019-54908-2.
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  15. Karmakar, S., K.A. Molla, D. Gayen, A. Karmakar and K. Das et al., 2019. Development of a rapid and highly efficient Agrobacterium-mediated transformation system for pigeon pea [Cajanus cajan (L.) Millsp]. GM Crops, Food, 10: 115-138.
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  16. Karmakar, S., K. Datta, K.A. Molla, D. Gayen, K. Das, S.N. Sarkar and S.K. Datta, 2019. Proteo-metabolomic investigation of transgenic rice unravels metabolic alterations and accumulation of novel proteins potentially involved in defence against Rhizoctonia solani. Sci. Rep., Vol. 9. 10.1038/s41598-019-46885-3.
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  17. Ganie, S.A., K.A. Molla, R.J. Henry, K.V. Bhat and T.K. Mondal, 2019. Advances in understanding salt tolerance in rice. Theor. Appl. Genet., 132: 851-870.
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  18. Vijayan, J., S. Senapati, S. Ray, K. Chakraborty and K.A. Molla et al., 2018. Transcriptomic and physiological studies identify cues for germination stage oxygen deficiency tolerance in rice. Environ. Exp. Bot., 147: 234-248.
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  19. Panda, D., K.A. Molla, M.J. Baig, A. Swain, D. Behera and M. Dash, 2018. DNA as a digital information storage device: hope or hype?. 3 Biotech, Vol. 8. 10.1007/s13205-018-1246-7.
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  20. Chattopadhyay, K., S.G. Sharma, T.B. Bagchi, K.A. Molla and S. Sarkar et al., 2018. Development of recombinant high yielding lines with improved protein content in rice (Oryza sativa L.). J. Agric. Sci., 156: 241-257.
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  21. Karmakar, S., K.A. Molla, K. Das, S.N. Sarkar, S.K. Datta and K. Datta, 2017. Dual gene expression cassette is superior than single gene cassette for enhancing sheath blight tolerance in transgenic rice. Sci. Rep., Vol. 7. 10.1038/s41598-017-08180-x.
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  22. Molla, K.A., S. Karmakar, P.K. Chanda, S.N. Sarkar, S.K. Datta and K. Datta, 2016. Tissue specific expression of Arabidopsis NPR1 gene in rice for sheath blight resistance without compromising phenotypic. Plant Sci., 250: 105-114.
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  23. Ghosh, S., K.A. Molla, S. Karmakar, S.K. Datta and K. Datta, 2016. Enhanced resistance to late blight pathogen conferred by expression of rice oxalate oxidase 4 gene in transgenic potato. Plant Cell Tissue Organ Culture, 10.1007/s11240-016-1011-8.
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  24. Molla, K.A., A.B. Debnath, S.A. Ganie and T.K. Mondal, 2015. Identification and analysis of novel salt responsive candidate gene based SSRs (cgSSRs) from rice (Oryza sativa L.). BMC Plant Biol., Vol. 15. .
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  25. Karmakar, S., K.A. Molla, P.K. Chanda, S.N. Sarkar, S.K. Datta and K. Datta, 2015. Green tissue-specific co-expression of chitinase and oxalate oxidase 4 genes in rice for enhanced resistance against sheath blight. Planta, 10.1007/s00425-015-2398-x.
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  26. Ganguly, M., K.A. Molla, S. Karmakar, K. Datta and S.K. Datta, 2014. Development of pod borer-resistant transgenic chickpea using a pod-specific and a constitutive promoter-driven fused cry1Ab/Ac gene. Theor. Appl. Genet., 127: 2555-2565.
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  27. Molla, K.A., S. Karmakar, P.K. Chanda, S. Ghosh, S.N. Sarkar, S.K. Datta and K. Datta, 2013. Rice oxalate oxidase gene driven by green tissue-specific promoter increases tolerance to sheath blight pathogen (Rhizoctonia solani) in transgenic rice. Mol. Plant Pathol., 14: 910-922.
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