Dr. Pathirage Kamal Perera
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Dr. Pathirage Kamal Perera

Professor
University of Colombo, Colombo, Western, Sri Lanka


Highest Degree
Ph.D. in Pharmacology from China Pharmaceutical University, China

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Biography

Professor. Pathirgae Kamal Perera [Ph.D. in Pharmacology (PR China)], is currently a Professor & Consultant Physician at the Faculty of Indigenous Medicine, University of Colombo, Sri Lanka. He specialized in Pharmacology, Therapeutics, and Immunology. He is certified and trained in Pharmacovigilance and Drug Safety at UMC, Sweden.

Area of Interest:

Pharmacology and Clinical Pharmacology
100%
Ayurveda
62%
Clinical Trials
90%
Immunopharmacology
75%
Traditional Medicine
55%

Research Publications in Numbers

Books
5
Chapters
8
Articles
67
Abstracts
106

Selected Publications

  1. de Silva, D., U. Senarath, P.K. Perera, 2023. Molecular mechanisms of antidiabetic effect of betulinic acid in lotus rhizome. Bratislava Med. J., 124: 707-717.
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  2. de Silva, D., U. Senarath and P.K. Perera, 2023. Exploration for analysis of medicinal foods used to manage dyslipidaemia in Sri Lankan traditional medicine. J. Med. Herbs Ethnomed., 9: 26-28.
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  3. Perera, P.K., J.M. Dahanayake and J.I.D. Diddeniya, 2023. Pharmacology, Toxicology, and Therapeutic Effects of Metals and Minerals Used in Traditional Medicine. In: Medical Geology: En route to One Health, Prasad, M.N.V. and M. Vithanage (Eds.), Wiley, United States, ISBN: 9781119867371, pp: 303-313.
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  4. Deepthika, S.H.K., K.P.K.R. Karunagoda and P.K. Perera, 2023. Pharmacological effects of Sesamum indicum; Systematic review. J. Sri Lanka Assoc. Adv. Sci., 5: 15-25.
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  5. Silva, H.D., P.K. Perera, S. Jayasinghe and S.D.S. Weliange, 2022. Efficacy and safety of Sri Lankan traditional medicine regimen for knee osteoarthritis: Study protocol for an open-label, active comparator, randomized controlled trial. Trials, 10.1186/s13063-022-06903-8.
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  6. Perera, W.L.S., P.K. Perera, C. Wijesundara, A.M. Ambagahawita, S.U. Fernando, S. Udara and.O. Bandaranayaka, 2022. Household-based survey on knowledge, attitudes, and practices towards dengue infection and prevention in a semi-urban area (Ja-Ela MOH area). Int J Med Parasitol Epidemiol Sci 2: 91-98.
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  7. Perera, P.K. and J.I.D. Diddeniya, 2022. In-vitro and in-vivo supportive research on medicinal properties of Cannabis sativa: A comprehensive review. J. Ayurvedic Her. Med., 8: 40-47.
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  8. Deepthika, K., K. Karunagoda and P.K. Perera, 2022. Efficacy and safety of three Ayurveda decoctions for Polycystic Ovary Syndrome: study protocol for a randomized, single-blind, three-arm, clinical trial, Running title: Ayurveda decoctions for PCOS: a study protocol. J. Sri Lanka Assoc. Adv. Sci., 4: 2-11.
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  9. Dahanayake, J.M. and P.K. Perera, 2022. Phoenix spp. (Phoenix acaulis, Phoenix sylvestris). In: Himalayan Fruits and Berries, Belwal, T., I. Bhatt and H. Devkota, (Eds.) Academic Press, pp: 313-319.
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  10. Alahakoon, P.V., P.K. Perera, C. Wijesundara and K.O. Bandaranayaka, 2022. Knowledge and attitudes on first aid among advanced level students in Gampaha Educational Zone, Sri Lanka. Arch. Internal Med. Res., 5: 172-181.
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  11. Perera, P.K., A.C.B. Meedeniya and N.H.A. Chamikara, 2021. Traditional Medicinal Plants of Sri Lanka and Their Derivatives of Benefit to the Nervous System. In: Medicinal Herbs and Fungi, Agrawal, D.C. and M. Dhanasekaran (Eds.), Springer, Singapore, ISBN: 978-981-33-4140-1, pp: 315-346.
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  12. Perera, P.K. and A.C.B. Meedeniya, 2021. Curcumin as a potential target for COVID19: Concept letter. Academia Lett., 10.20935/al3484.
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  13. Malge, N.R., A.M.P.W. Bandara, W.L.R. Keerthirathna, D.M.I. Dissanayake, P.K. Perera, C. Witharana and L.D.C. Peiris, 2021. Antioxidant and anti-proliferative activities of smilax zeylanica root and rhizome extract against liver carcinoma cells. J. Herbs, Spices Medic. Plants, 10.1080/10496475.2021.1891178.
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  14. Karunagoda, K.P.K.R., P.K. Perera, H. Senanayake and S.D.S. Weliange 2021. Efficacy and Safety of the Two Ayurveda Drug Regimens in Uterine Fibroids: A Randomized Single-Blind Clinical Trial. Evidence-Based Complementary Altern. Med. 2021: 1-8.
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  15. Karunagoda, K., K. Perera and H. Senanayake, 2021. Pedagogical review on Ayurveda concept of uterine fibroids. J. Indian Syst. Med., 9: 3-11.
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  16. Diddeniya, I.D. and P.K. Perera, 2021. A review on evidence-based clinical research in traditional medicine for combat COVID-19. Int. J. Pharm. Sci. Res. 12: 4588-4599.
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  17. Weerakoon, W.A.S.S., P.K. Perera, K. Samarasinghe, D. Gunasekera and T.S. Suresh, 2020. Acute and subchronic oral safety profiles of the sudarshana suspension. Evidence-Based Complementary Altern. Med., Vol. 2020. 10.1155/2020/2891058.
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  18. Perera, P., N. Kumarasinghe, M. Pallie, C. Goonasekara and M. Arawwawala, 2020. Efficacy and safety of freeze-dried form of Tragia involucrata L. decoction in treating diabetes: a randomized controlled clinical trial. Clin. Trials Degenerative Dis., 10.4103/2542-3975.300614.
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  19. Pallie, M.S., P.K. Perera, N. Kumarasinghe, M. Arawwawala and C.L. Goonasekara, 2020. Ethnopharmacological use and biological activities of Tragia involucrata L. Evidence-Based Compl. Alt. Med., 10.1155/2020/8848676.
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  20. Dahanayake, J.M., P.K. Perera, P. Galappaththy and D. Samaranayake, 2020. Efficacy and safety of two Ayurvedic dosage forms for allergic rhinitis: Study protocol for an open-label randomized controlled trial. Trials, 10.1186/s13063-019-4004-1.
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  21. Dahanayake, J.M., P.K. Perera, P. Galappatty, H.D.S.M. Perera and L.D.A.M. Arawwawala, 2019. Comparative phytochemical analysis and antioxidant activities of tamalakyadi decoction with its modified dosage forms. Evidence-Based Comp. Altern. Med., 2019: 1-9.
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  22. Weerakoon, W.A.S.S., P.K. Perera, D. Gunasekera and T.S. Suresh, 2018. Evaluation of the in vitro and in vivo antioxidant potentials of Sudarshana powder. Evidence-Based Complementary Altern. Med., Vol. 2018. 10.1155/2018/6743862.
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  23. Stranieri, A., K. Butler-Henderson, T. Sahama, P.K. Perera and J.L. Da Silva et al., 2017. A visual grid to digitally record an Ayurvedic Prakriti assessment; a first step toward integrated electronic health records. J. Tradit. Complement. Med., 7: 264-268.
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  24. Perera, P.K., 2017. Traditional medicine based drug development. Biochem. Anal. Biochem., Vol. 6. 10.4172/2161-1009.1000311.
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  25. Pallie, M.S., P.K. Perera, C.L. Goonasekara, K.M.N. Kumarasinghe and L.D.A.M. Arawwawala, 2017. Evaluation of diuretic effect of the hot water extract of standardized Tragia involucrata Linn., in rats. Int. J. Pharmacol., 13: 83-90.
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  26. Pallie, M.S., P.K. Perera, C.L. Goonasekara, K.M.N. Kumarasinghe and L.D.A.M. Arawwawala, 2017. Tragia spp: Assessment of diuretic activity and standardization of the whole plant. Am. J. Ethnomed., Vol. 4, No. 1. 10.21767/2348-9502.100005.
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  27. Vajira, P.S.S., S.D. Hapuarachchi and P.K. Perera, 2016. Standardization and quality control of Centella asiatica Linn. (Gotukola) dried powder and capsules. World J. Pharm. Pharmaceut. Sci., 5: 42-50.
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  28. Fernando, C.D., D.T. Karunaratne, S.D. Gunasinghe, M.D. Cooray, P. Kanchana, C. Udawatte and P.K. Perera, 2016. Inhibitory action on the production of Advanced Glycation End Products (AGEs) and suppression of free radicals in vitro by a Sri Lankan polyherbal formulation Nawarathne Kalka. BMC Complement. Altern. Med., Vol. 16. 10.1186/s12906-016-1178-x.
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  29. Perera, P.K., J. Dahanayake and K. Karunagoda, 2015. A brief survey on awareness of pharmacovigilance among ayurveda physicians in Sri Lanka. TANG [Humanit. Med.], Vol. 5, No. 1. 10.5667/tang.2014.0022.
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  30. Perera, H.A.R.P., K. Karunagoda, P.K. Perera, K. Samarasingha and L.D.A.M. Arawwawala, 2015. Phyllanthus niruri Linn grown in Sri Lanka: Evaluation on phyto and physico-chemical properties of the whole plant. World J. Pharm. Pharmaceut. Sci., 4: 1452-1459.
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  31. Perera, P.K., M. Perera and N. Kumarasinghe, 2014. Effect of Sri Lankan traditional medicine and Ayurveda on Sandhigata vata (osteoarthritis of knee joint). AYU: Int. Quart. J. Res. Ayurveda, 35: 411-415.
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  32. Perera, P.K. and J. Dahanayake, 2013. Analytical study of Coscinium fenestratum (Gaertn.) Colebr. stem powder of different market samples in Sri Lanka. Sri Lanka J. Indigenous Med., 3: 180-181.
  33. Perera, P.K. and Y. Li, 2012. Functional herbal food ingredients used in type 2 diabetes mellitus. Pharm. Rev., 6: 37-45.
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  34. Peng, C., P.K. Perera, Y.M. Li, W.R. Fang, L.F. Liu and F.W. Li, 2012. Anti-inflammatory effects of Clematis chinensis Osbeck extract (AR-6) may be associated with NF-κB, TNF-α and COX-2 in collagen-induced arthritis in rat. Rheumatol. Int., 32: 3119-3125.
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  35. Perera, P.K., C. Peng, L. Xue, Y. Li and C. Han, 2011. Ex vivo and in vivo effect of Chinese herbal pill Yi Shen Juan Bi (YJB) on experimental arthritis. J. Ethnopharmacol., 134: 171-175.
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  36. Perera, P.K. and Y. Li, 2011. Mushrooms as a functional food mediator in preventing and ameliorating diabetes. Funct. Foods Health Dis., 1: 161-171.
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  37. Perera, P.K. and Y. Li, 2011. Anti rheumatic herbal compound drug Yi Shen Juan Bi (YJB) as selective cytokines target in rheumatoid arthritis. Sri Lanka J. Indigenous Med., 1: 86-90.
  38. Perera, P.K., Y. Li, C. Peng, W. Fang and C. Han, 2010. Immunomodulatory activity of a Chinese herbal drug Yi Shen Juan Bi in adjuvant arthritis. Indian J. Pharmacol., 42: 65-69.
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  39. Perera, P.K., C. Peng, X. Lv, Y.M. Li, W.R. Fang and C.F. Han, 2010. Effects of Yishen Juanbi (YJB) pill on experimental rheumatoid arthritis. Chin. J. Nat. Med., 8: 57-61.
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  40. Perera, P.K. and Y. Li, 2010. Improve students' effectiveness in lab sessions using instant lab report. Int. J. Pharm. Teach. Pract., 1: 24-26.
  41. Peng, C., P.K. Perera, Y. Li, Q. Teng and C. Han, 2010. Experimental study on secondary affection of rats' collagen arthritis treated with Yishen Juanbi pill. Chin. J. Tradit. Med. Sci. Technol., 17: 389-390.
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