Area of Interest:

Pharmacology and Toxicology

100%

Anti Inflammatory Compounds

62%

Immunomodulatory Compounds

90%

Chemotherapeutics

75%

Bioactive Compounds

55%

Research Publications in Numbers

Books
0

Chapters
0

Articles
0

Abstracts
0

Selected Publications

Ali, A.S., A.A. Altayari, L.M. Khan, S.E. Alharthi and O.A. Ahmed et al., 2020. Colon-targeted therapy of tacrolimus (FK506) in the treatment of experimentally induced colitis. Pharmacology, 10.1159/000505101.
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Alahmadi, A.A., A.A. Alzahrani, S.S. Ali, B.A. Alahmadi, R.A. Arab and N.A.E.A. El-Shitany, 2020. Both Matricaria chamomilla and metformin extract improved the function and histological structure of thyroid gland in polycystic ovary syndrome rats through antioxidant mechanism. Biomolecules, Vol. 10. 10.3390/biom10010088.
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El-Shitany, N.A.E.A., A.T. Abbas, S.S. Ali, B. Eid and S. Harakeh et al., 2019. Nanoparticles ellagic acid protects against cisplatin-induced hepatotoxicity in rats without inhibiting its cytotoxic activity. Int. J. Pharmacol., 15: 465-477.
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El-Shitany, N.A. and B.G. Eid, 2019. Icariin modulates carrageenan-induced acute inflammation through HO-1/Nrf2 and NF-kB signaling pathways. Biomed. Pharmacother., Vol. 120. 10.1016/j.biopha.2019.109567.
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Neamatallah, T., N.A. El-Shitany, A.T. Abbas, S.S. Ali and B.G. Eid, 2018. Honey protects against cisplatin-induced hepatic and renal toxicity through inhibition of NF-κB-mediated COX-2 expression and the oxidative stress dependent BAX/Bcl-2/caspase-3 apoptotic pathway. Food Funct., 9: 3743-3754.
Direct Link |
Khattab, H.A.R.H., U.A. Abdel-Dayem, H.A. Jambi, A.T. Abbas, M.T.A. Abdul-Jawad and N.A.E.A.El-Shitany, 2018. Licorice (Glycyrrhizza glabra) extract prevents production of th2 cytokines and free radicals induced by ova albumin in mice. Int. J. Pharmacol., 14: 1072-1079.
Alzahrani, A.A., A.A. Alahmadi, S.S. Ali, B.A. Alahmadi, R.A. Arab, L.F. Wahman and N.A. El-Shitany, 2018. Biochemical and histological evidence of thyroid gland dysfunction in estradiol valerate model of the polycystic ovary in Wistar rats. Biochem. Biophys. Res. Commun., 514: 194-199.
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El‐Shitany, N.A. and B. Eid, 2017. Proanthocyanidin protects against cisplatin‐induced oxidative liver damage through inhibition of inflammation and NF‐κβ/TLR‐4 pathway. Environ. Toxicol., 32: 1952-1963.
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Almasaudi, S.B., A.T. Abbas, R.R. Al-Hindi, N.A. El-Shitany and U.A. Abdel-Dayem et al., 2017. Manuka honey exerts antioxidant and anti-inflammatory activities that promote healing of acetic acid-induced gastric ulcer in rats. Evid. Based. Complement Alternat Med., 10.1155/2017/5413917.
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Khattab, H.A.H., N.A. El-Shitany and A.K.S. Al-lily, 2016. Hibiscus sabdariffa extract alleviate nephrotoxicity induced by adriamycin in male rats. Biosci. Res., 13: 32-42.
Khattab, H.A.H., N.A. El-Shitany and A.K.S. Al-lily, 2016. Effect of roselle (Hibiscus sabdariffa) against adriamycin induced-cardiotoxicity in male rats. Int. J. Pharm. Res. Allied Sci., 5: 519-534.
Direct Link |
El-haggar, S.M., N.A. El-Shitany, M.F. Mostafa and N.A. El-Bassiouny, 2016. Metformin may protect nondiabetic breast cancer women from metastasis. Clin. Exp. metastasis, 33: 339-357.
Direct Link |
El-Shitany, N.A. and K. El-Desoky, 2016. Protective effects of carvedilol and vitamin c against azithromycin-induced cardiotoxicity in rats via decreasing ros, IL1-β, and TNF-α production and inhibiting NF-κB and caspase-3 expression. Oxid. Med. Cell. Longev., 10.1155/2016/1874762.
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Almasaudi, S.B., N.A. El-Shitany, A.T. Abbas, U.A. Abdel-dayem, S.S. Ali, S.K.A.l. Jaouni and S. Harakeh, 2016. Antioxidant, anti-inflammatory, and antiulcer potential of manuka honey against gastric ulcer in rats. Oxid. Med. Cell. Longev., 10.1155/2016/3643824.
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Khattab, H.A.H., N.A. El-Shitany, I.Z.A. Abdallah, F.M. Yousef and H.M. Alkreathy, 2015. Antihyperglycemic potential of grewia asiatica fruit extract against Streptozotocin-Induced hyperglycemia in rats: Anti-Inflammatory and antioxidant mechanisms. Oxid. Med. Cell. Longevity, 10.1155/2015/549743.
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El-Shitany, N.A., L.A. Shaala, A.T. Abbas, U.A. Abdel-Dayem and E.I. Azhar et al., 2015. Evaluation of the anti-inflammatory, antioxidant and immunomodulatory effects of the organic extract of the red sea marine sponge Xestospongia testudinaria against carrageenan induced rat paw inflammation. PLoS ONE, Vol. 10. 10.1371/journal.pone.0138917.
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El-Shitany, N.A. and K. El-Desoky, 2015. Cromoglycate, not ketotifen, ameliorated the injured effect of warm ischemia/reperfusion in rat liver: role of mast cell degranulation, oxidative stress, proinflammatory cytokine, and inducible nitric oxide synthase. Drug des. Dev. Ther., 9: 5237-5246.
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Aly, H.A., N.A. El-Shitany, H.A. El-Beshbishy and O.M. Ashour, 2015. Ameliorative effect of lycopene against 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin-induced rat liver microsomal toxicity: An in vitro study. Toxicol. Indust. Health, 31: 938-950.
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El-Shitany, N.A., E.A. El-Bastawissy and K. El-desoky, 2014. Ellagic acid protects against carrageenan-induced acute inflammation through inhibition of nuclear factor kappa B, inducible cyclooxygenase and proinflammatory cytokines and enhancement of interleukin-10 via an antioxidant mechanism. Int. immunopharmacol., 19: 290-299.
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Abbas, A.T., N.A. El-Shitany, L.A. Shaala, S.S. Ali, E.I. Azhar, U.A. Abdel-dayem and D.T.A. Youssef, 2014. Red sea suberea mollis sponge extract protects against ccl4-induced acute liver injury in rats via an antioxidant mechanism. Evidence-Based Complementary Altern. Med., 10.1155/2014/745606.
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El-Shitany, N.A., O.A. Tolba, M.R. El-Shanshory and E.E. El-Hawary, 2012. Protective effect of carvedilol on adriamycin-induced left ventricular dysfunction in children with acute lymphoblastic leukemia. J. cardiac failure, 18: 607-613.
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Al-Biltagi, M., O.A.R.E. Tolba, M.R. El-Shanshory, N.A.E. Shitany and E. El-Sayed El-Hawary, 2012. Strain echocardiography in early detection of Doxorubicin-induced left ventricular dysfunction in children with acute lymphoblastic leukemia. ISRN Pediatr., 10.5402/2012/870549.
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El-Masry, T.A., A.M. Emara and N.A. El-Shitany, 2011. Possible protective effect of propolis against lead-induced neurotoxicity in animal model. J. Evol. Biol. Res., 3: 4-11.
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El‐Shitany, N.A., S.A. El‐Masry, M.A. El‐Ghareib and K. El‐Desoky, 2010. Thioctic acid protects against carrageenan‐induced acute inflammation in rats by reduction in oxidative stress, downregulation of COX‐2 mRNA and enhancement of IL‐10 mRNA. Fundam. Clin. Pharmacol., 24: 91-99.
El-Shitany, N.A., S. Hegazy and K. El-desoky, 2010. Evidences for antiosteoporotic and selective estrogen receptor modulator activity of silymarin compared with ethinylestradiol in ovariectomized rats. Phytomedicine, 17: 116-125.
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Draz, E.I., N.A. El-Shitany, T.A. Salem and K. El-Desoky, 2009. Nigella sativa fixed oil chronic toxicity: Experimental study. Egypt. J. Forensic Sci. Appl. Toxicol., 9: 35-49.
El-Shitany, N.A., S. El-Haggar and K. El-Desoky, 2008. Silymarin prevents adriamycin-induced cardiotoxicity and nephrotoxicity in rats. Food Chem. Toxicol., 46: 2422-2428.
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Awara, W.M., M.A. Nasra and N.A. El-Shitany, 1998. Role of nitric oxide in adjuvant arthritis in rats. do dexamethasone and indomethacin produce their anti-inflammatory actions through inhibition of nitric oxide synthase. Med. J. Cairo. Univ., 66: 973-988.