Dr. Eziuche Amadike
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Dr. Eziuche Amadike

Senior Lecturer
Abia State University, Nigeria

Highest Degree
Ph.D. in Biochemistry from Heriot-Watt University, Edinburgh, UK

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Area of Interest:

Biomedical Sciences
100%
Biochemistry
62%
Food Biotechnology
90%
Toxicity
75%
Chemical Biology
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Ugbogu, E.A., I.E. Akubugwo, V.C. Ude, J. Gilbert and B. Ekeanyanwu, 2019. Toxicological evaluation of phytochemical characterized aqueous extract of wild dried Lentinus squarrosulus (Mont.) mushroom in rats. Toxicol. Res., 35: 181-190.
  2. Ugbogu, E.A., E.I. Akubugwo, V.C. Ude, O. Emmanuel, N.O. Okomba, C. Ibe and O. Onyero, 2019. Safety evaluation of an aqueous extract of Termitomyces robustus (Agaricomycetes) in wistar rats. Int. J. Medicinal Mushrooms, 21: 193-203.
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  3. Ugbogu, E.A., C.D. Nwoku, V.C. Ude and O. Emmanuel, 2019. Evaluating bioactive constituents and toxicological effects of aqueous extract of fermented Pentaclethra macrophylla seeds in rats. Avicenna J. Phytomed., 10: 101-113.
  4. Ogbonna, C.E., F.I. Nwafor and E.A. Ugbogu, 2019. physiochemical properties and anticipated performance of selected plant species in Lokpaukwu quarry Site in Abia State, Nigeria. J. Environ. Pollut. Hum. Health, 7: 7 -14.
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  5. Elghandour, M.M.Y., Z.L. Tan, S.H. Abu Hafsa, M.J. Adegbeye and R. Greiner et al., 2019. Saccharomyces cerevisiae as a probiotic feed additive to non‐and pseudo‐ruminant feeding: A Review. J. Applied Microbiol., 10.1111/jam.14416.
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  6. Elghandour, M.M., A. Khusro, M.J. Adegbeye, Z. Tan and S.H. Abu Hafsa et al., 2019. Dynamic role of single‐celled fungi in ruminal microbial ecology and activities. J. Applied Microbiol., 10.1111/jam.14427.
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  7. Ekweogu, C.N., V.C. Ude, P. Nwankpa, O. Emmanuel and E.A. Ugbogu, 2019. Ameliorative effect of aqueous leaf extract of Solanum aethiopicum on phenylhydrazine-induced anaemia and toxicity in rats. Toxicol Res., .
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  8. 1. Ugbogu, E.A., M.M.M.Y. Elghandour, V.O. Ikpeazu and G.R. Buendía et al., 2019. The potential impacts of dietary plant natural products on the sustainable mitigation of methane emission from livestock farming. J. Cleaner Prod., 213: 915-925.
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  9. Ugbogu, E.A., V.C. Ude, I. Elekwa, U.O. Arunsi, C. Uche-Ikonne and C. Nwakanma, 2018. Toxicological profile of the aqueous-fermented extract of Musa paradisiacal in rats. Avicenna J. Phytomed., 8: 478-487.
  10. Ugbogu, E.A., O. Emmanuel, A.Z.M. Salem and M.M.M.Y. Elghandour, 2018. Nutritional composition of Termitomyces robustus (Agaricomycetes) and Lentinus squarrosulus (Mont.) singer in South East Nigeria. Agroforest Syst., .
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  11. Ugbogu, E.A. and O. Emmanuel, 2018. Nutritional potential of aqueous soaked fermented Pentaclethra macrophylla (Benth) seeds. Am. J. Food Sci. Technol., 6: 108-113.
    CrossRef  |  
  12. Orji, F.A., O.C. Ugbogu, E.A. Ugbogu, A. Barbabosa-Pliego and J.C. Monroy et al., 2018. Pathogenic flora composition and overview of the trends used for bacterial pathogenicity identifications. Microb. Pathog., 121: 139-146.
  13. Ogbonna, C.E., F.I. Nwafor, E.A. Ugbogu and K. Nwazue, 2018. Assessment of foliar parameters and air pollution tolerance of broad leaved trees in Ugwuele Quarry Site, Uturu, Nigeria. Applied Ecol. Environ. Sci., 6: 48-56.
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  14. Mariezcurrena-Berasain, M.D., M.A. Mariezcurrena-Berasain, D.L. Pinzon-Martínez, H.D. Arzate-Serrano, E.A. Ugbogu and A.A.M. Salem, 2018. Influence of dietary supplementation of garlic (Allium sativum L.) extract on cecal productions of total gas, carbon dioxide and fermentation profiles in rabbits. Agroforest. Syst., .
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  15. Mariezcurrena-Berasain, M.A., G. Velázquez-Garduno, P.M. Marín-Mendoza, A.B. Pliego, L.F.V. Castillo et al., 2018. Sensitivity of Coriandrum sativum extract on bacterial pathogens isolated from digestive system of rabbits, and its role on in vitro cecal gas production and fermentation. Microb. Pathog., 123: 18-23.
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  16. Ikpeazu, V.O., E.A. Ugbogu, O. Emmanuel, C. Uche-Ikonne, B. Okoro and J. Nnaemeka, 2018. Evaluation of the safety of oral intake of aqueous extract of Stigma maydis (corn silk) in rats. Acta Sci. Polonorum Technol. Aliment., 17: 387-397.
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  17. Emmanuel, O., E.A. Ugbogu, A. Uwadinachi, S. Okeke and V. Achulonu, 2018. A comparative study on micronutrients and antinutrients of leaf extracts of Pterocarpus soyauxii and Pterocarpus santalinoides. J. Compl. Med. Res., 7: 131-137.
    CrossRef  |  
  18. Elghandour, M.M., X. Antolin-Cera, A.Z. Salem, A. Barbabosa-Pliego, B. Valladares-Carranza and E.A. Ugbogu, 2018. Influence of Escherichia coli inclusion and soybean hulls based diets on ruminal biomethane and carbon dioxide productions in sheep. J. Clean. Prod., 192: 766-774.
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  19. Cipriano-Salazar, M., S. Rojas-Hernandez, J. Olivares-Perez, R. Jimenez-Guillen, B. Cruz-Lagunas, L.M. Camacho-Diaz and A.E. Ugbogu, 2018. Antibacterial activities of tannic acid against isolated ruminal bacteria from sheep. Microbial Pathog., 117: 255-258.
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  20. Ugbogu, A.E., U.O. Arunsi, O.O. Uche-Ikonne, V.C. Ude and E. Okezie, 2017. Antiulcerogenic potentials of fermented aqueous extract of Pentaclethra macrophylla (Benth) seeds. Am. J. Biomed. Res., 5: 57-64.
  21. Okezie, E., E.U. Amadike, A.O. Aggie and A.S. Chinedu, 2017. Proximate, antinutritional and mineral estimation of some selected consumed green vegetables in Afaha Eket, Akwa-Ibom state, Nigeria. Am. J. Food Sci. Technol., 5: 182-191.
    CrossRef  |  
  22. Ogbonna, C.E., A.E. Ugbogu, F.C. Otuu, N.E. Mbaogu and A.R. Johnson, 2017. Influence of rock quarrying activities on the physiochemical characteristics of selected edible fruit trees in uturu, abia state, Nigeria. Appl. Ecol. Environ Sci., 5: 1-9.
  23. Ikpeazu, O.V., I. Elekwa, A.E. Ugbogu, U.O. Arunsi and C. Uche-Ikonne, 2017. Preliminary evaluation of anti-ulcer potential of aqueous extract of fermented unripe Musa paradisiacal in wistar rats. Am. J. Biomed. Res., 5: 17-23.
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  24. Hernandez, A., A.E. Kholif, M.M.Y. Elghandour, L.M. Camacho and M.M. Cipriano et al., 2017. Effectiveness of xylanase and Saccharomyces cerevisiae as feed additives on gas emissions from agricultural calf farms. J. Cleaner Prod., 148: 616-623.
    CrossRef  |  Direct Link  |  
  25. Elekwa, I., A.E. Ugbogu, S.C. Okereke and E. Okezie, 2017. A review of selected medicinal plants with potential health benefits in South-Eastern Nigeria. Int. J. Pharma Chem., 6: 162-171.
  26. Ugbogu, O.C., R.A. Onyeagba, A.E. Ugbogu and V.O. Nwaugo, 2016. Heavy metal levels and potential pathogens of surface water and sediments of two man-made lakes at Lokpa Umuchieze, Abia State Nigeria. Int. J. Environ. Biol., 6: 4-10.
  27. Ugbogu, E.A., K. Wang, L.M. Schweizer and M. Schweizer, 2016. Metabolic gene products have evolved to interact with the cell wall integrity pathway in Saccharomyces cerevisiae. Yeast Res., Vol. 16. 10.1093/femsyr/fow092.
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  28. Ugbogu, E.A., E. Okezie, I. Elekwa, F. Uhegbu, E. Akubugwo, G.C. Chinyere, F. Ewuzie and C.J. Ugorji, 2016. Toxicological assessment of the aqueous dried leaf extracts of Senna alata L. in wistar rats. Afr. J. Pharm. Pharmacol., 10: 709-717.
  29. Ugbogu, E.A. and O.C. Ugbogu, 2016. A review of microbial protein production: Prospects and challenges. FUW Trends Sci. Technol. J., 1: 182-185.
  30. Ugbogu, A.E., E. Okezie, C. Uche-Ikonne, M. Duru and O.C. Atasie, 2016. Toxicity evaluation of the aqueous stem extracts of Senna alata in Wistar rats. Am. J. Biomed. Res., 4: 80-86.
  31. Osuocha, K.U., E.I. Akubugwo, G.C. Chinyere and A.E. Ugbogu, 2016. Seasonal impact on phyto-accumulation potentials of selected edible vegetables grown in Ishiagu quarry mining effluent discharge soils. Afr. J. Environ. Sci. Technol., 10: 34-43.
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  32. Osuocha, K.U., E.C. Chukwu, E.A. Ugbogu, O.C. Atasie and C.E. Ogbonna, 2016. Effects of quarry mining activities on the nutritional composition of edible vegetables in Ishiagu, Ebonyi state, Nigeria. J. Exp. Biol. Agric. Sci., 4: 467-474.
    CrossRef  |  
  33. Ogbonna, C.E., I.C. Enete, O.C. Ugbogu, C.U. Okeke, F.C. Otuu and A.E. Ugbogu, 2016. Oxidative stress potential of lead-zinc mining on selected plants growing in Ishiagu, Nigeria.. Ethiopian J. Environ. Studies Managt., 9: 303-314.
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  34. Chinyere, G.C., K.U. Osuocha, C.E. Offor and A.E. Ugbogu, 2016. Seasonal impact of cassava mill effluents (CME) on dumpsites physicochemical parameters and selected enzyme activities in Isuikwuato area, Abia State, Nigeria. Int. J. Sci. Environ. Technol., 5: 1787-1805.
  35. Uhegbu, F.O., C. Imo and A.E. Ugbogu, 2015. Some biochemical changes in serum of female albino rats administered aqueous extract of Piper guineense Schumach seeds. Int. J. Biochem. Res. Rev., 8: 1-7.
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  36. Uhegbu, F.O., C. Imo and A.E. Ugbogu, 2015. Effect of aqueous extract of Piper guineense seeds on some liver enzymes, antioxidant enzymes and some hematological parameters in Albino rats. Int. J. Plant Sci. Ecol., 1: 167-171.
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  37. Osuocha, K.U., E.I. Akubugwo, G.C. Chinyere and A.E. Ugbogu, 2015. Seasonal impact on physicochemical characteristics and enzymatic activities of Ishiagu quarry mining effluent discharge soils. Int. J. Curr. Biochem. Res., 3: 55-66.
  38. Ogodo, A.C., O.C. Ugbogu, A.E. Ugbogu and C.S. Ezeonu, 2015. Production of mixed fruit (pawpaw, banana and watermelon) wine using Saccharomyces cerevisiae isolated from palm wine. SpringerPlus, Vol. 4. 10.1186/s40064-015-1475-8.
    CrossRef  |  
  39. Ogbonna, C.E., I.C. Enete, A.E. Ugbogu and A.U. Egbu, 2015. Air pollution tolerance index (APTI) of some plants in the Ishiagu Lead-Zinc mining area, South Eastern Nigeria. World J. Phytoremed. Earth Sci., 2: 109-114.
  40. Ogbonna, C.E., F.C. Otuu, N.T. Iwueke, A.U. Egbu and A.E. Ugbogu, 2015. Biochemical properties of trees along Umuahia-Aba expressway, Nigeria. Int. J. Environ. Biol., 5: 99-103.
  41. Ogbonna, C.E., A.E. Ugbogu, F.C. Otuu, E.N. Adinna and C.U. Okeke, 2015. Phytoremediation potential of some plants in the Ishiagu Lead-Zinc mining area, Nigeria. World J. Phytoremediation Earth Sci., 2: 99-108.
  42. 38. Ogbonna, C.E., F.C. Otuu, O.C. Ugbogu, V.O. Nwaugo and A.E. Ugbogu, 2015. Public health implication of heavy metal contamination of plants growing in the lead zinc mining area of ishiagu, Nigeria. Int. J. Biodiv. Environ. Sci., 7: 76-86.
  43. Ugbogu, A.E., E.I. Akubugwo, F.O. Uhegbu, C.G. Chinyere, O.C. Ugbogu and K.A. Oduse, 2014. Quality assessment profile of Jatropha curcas (L.) seed oil from Nigeria. Int. Food Res. J., 21: 735-741.
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  44. Ugbogu, A.E. and B.A. Amadi, 2014. Biochemical composition of month beans (V.aconitifolia) and pidgeon pea (C.cajan). Intr. J. Med. Sci. Res., 1: 001-008.
  45. Ogueri, C.C., I. Elekwa, V.C. Ude and A.E. Ugbogu, 2014. Effect of aqueous extract of guava (Psidium guajava) leaf on blood glucose and liver enzymes in alloxan induced diabetic rats. Br. J. Pharma. Res., 4: 1079-1087.
  46. Odika, P.C., E.I. Akubugwo and A.E. Ugbogu, 2014. Assessment of Njaba River on biochemical parameters using rats. Int. J. Biodiver. Environ. Sci., 1: 001-013.
  47. Egejuru, L.O., E.I. Akubugwo, V.C. Ude, O.C. Ugbogu and A.E. Ugbogu, 2014. Evaluation of physicochemical properties, microbial loads and enzymes activity studies of agrochemicals on the Imo-River basin farm in Imo State Nigeria. Int. J. Curr. Microbiol. App. Sci., 3: 776-786.
  48. Duru, M., B. Amadi, A. Ugbogu and A. Eze, 2014. Effect of “Udu”, an antimalarial herbal preparation on visceral organ weight and blood lipid profiles in wistar rats. J. Pharm. Clin. Sci., 8: 1-7.
  49. Uhegbu, F.O., A.E. Ugbogu, K.C. Nwoku and V.C. Ude, 2013. Effect of soybean oil supplemented diet on fatty acid level and lipid profile of albino rats. Br. J. Pharma. Toxicol., 4: 158-162.
  50. Uhegbu, F.O., A.E. Ugbogu and K.C. Nwoku, 2013. Effect of aqueous extract of pear seeds on some biochemical parameters in albino rats. J. Res. Biochem., 2: 110-115.
  51. Ugbogu, O.C., R.A. Onyeagba, V.O. Nwaugo, A.E. Ugbogu and C.E. Ogbonna, 2013. Physicochemical and microbiological quality of soils surrounding two man-made lakes in Abia State, Nigeria. ABSU J. Environ. Sci. Tech., 3: 335-342.
  52. Ugbogu, E.A., S. Wippler, M. Euston, E.N. Kouwenhoven, A.P. Brouwer, L.M. Schweizer and M. Schweizer, 2013. The contribution of the nonhomologous region of Prs1 to the maintenance of cell wall integrity and cell viability. FEMS Yeast Res., 13: 291-301.
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  53. Ugbogu, A.E., E.I. Akubugwo, E.J.J. Iweala, F.O. Uhegbu, G.C. Chinyere and N.A. Obasi, 2013. Role of phytochemicals in chemoprevention of cancer: A review. Int. J. Pharm. Chem. Sci., 2: 566-575.
  54. Obasi, N.A., E.I. Akubugwo, K.M. Kalu, A.E. Ugbogu and U.C. Okorie, 2013. Toxicological assessment of various metals on selected edible leafy plants of Umuka and Ubahu dumpsites in Okigwe of Imo State, Nigeria. J. Exp. Biol. Agric. Sci., 1: 441-453.
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  55. Majesty, K.D., A.A. Benjamin, T.A. Chioma, E.U. Amadike and L.O. Nchekwube, 2013. Assessment of" Nduduagworagwo", a traditional recipe of Akokwa people in Ideato North LGA of Imo State, Nigeria on body weight and somebiochemical parameters. Continental J. Food Sci. Technol., 7: 15-21.
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  56. Majesty, D., U. Amadike and A. Benjamin, 2013. Effect of Solanum macrocarpon fruit on haematology, hepatic and renal function. Adv. Biochem., 1: 28-32.
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  57. Majesty, D., A. Benjamin, E. Adindu and U. Amadike, 2013. Evaluation of “mgbam” traditional food on haematological profile and some selected biochemical parameters following consumption. Elixir Food Sci., 64: 19345-19349.
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  58. Duru, M.K.C., B.A. Amadi, A.E. Eze, A.E. Ugbogu and N. Onuoha, 2013. In vivo studies of Solanum aethiopicum fruit on some biochemical parameters using rats. J. Chem. Pharm. Res., 5: 1-4.
  59. Duru, M., K. Nwanekwu, A. Ugbogu, A. Jeoseph, C. Amadi and P. Ujubuonu, 2013. Urine therapy and its effects on some biochemical parameters using rats. Continental J. Biomed. Sci., 7: 12-17.
  60. Duru, M., B. Amadi, A. Ugbogu and N. Onuoha, 2013. Effect of “nduduagworagwo” traditional food on haematology, hepatic and renal function of rats. Asian J. Agric. Food Sci., 1: 21-26.
  61. Chinyere, G.C., E.S. Obisike, A.E. Ugbogu and K.U. Osuocha, 2013. Studies on municipal solid wastes dumping on soil anions, cations and selected enzymes activities at njoku sawmill waste dumpsite, owerri municipal, Imo State, Nigeria. Ethiop. J. Environ. Stud. Manage., 6: 774-783.
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  62. Chinyere, C.G., A.E. Iroha and U.E. Amadike, 2013. Effect of altering palm oil and cassava mill effluents pH before dumping on dumpsite soils physicochemical parameters and selected enzyme activities. J. Biod. Environ. Sci., 3: 46-58.
  63. Amadi, B., N. Onuoha, C. Amadi, A. Ugbogu and M. Duru, 2013. Elemental, amino acid and phytochemical constituents of fruits of three different species of eggplant. Int. J. Med. Aromat. Plants, 3: 200-203.
  64. Uhegbu, F.O., G.C. Chinyere, A.E. Ugbogu and K.C. Nwoku, 2012. Studies on some biochemical effects of aqueous leaf Extract of Landolphia owerrience on albino rats. J. Res. Biol., 2: 410-417.
  65. Uhegbu, F.O., G.C. Chinyere, A.E. Ugbogu and K.C. Nwoku, 2012. Arsenic and chromium in sea foods from Niger Delta of Nigeria: A case study of Warri, Delta State. Bull. Environm. Contam. Toxicol., 89: 424-427.
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  66. Ude, V.C., F.O. Uhegbu, E.I. Akubugwo, O.C. Ugbogu and A.E. Ugbogu, 2012. Effect of selected well water sources at Ishiagu quarry site, Ebonyi State, Nigeria on basic haematological parameters in peripheral blood of albino rats. Int. J. Biochem Biotechnol., 1: 194-197.
  67. Duru, M., C. Amadi, A. Ugbogu, A. Eze and B. Amadi, 2012. Phytochemical, vitamin and proximate composition of Dacryodes edulis fruit at different stages of maturation. Asian J. Plant Sci. Res., 2: 437-441.
  68. Akubugwo, E.I., N.A. Obasi, G.C. Chinyere, E. Eze, O. Nwokeoji and A.E. Ugbogu, 2012. Phytoaccumulation effect of Amaranthus hybridus L grown on buwaya refuse dumpsite in Chikun, Nigeria on heavy metals. J Biodiver Environ Sci., 2: 10-17.
  69. Akubugwo, E.I., G.C. Chinyere, F.O. Uhebgu, O.C. Ugbogu and A.E. Ugbogu, 2012. Some biochemical changes in serum of male albino rats treated with aqueous leaf extract of Phyllanthus amarus. Int. J. Applied Bio. Pharma Technol., 3: 385-388.
  70. Akubugwo, I.E., C.J. Ofoegbu, C.C. Dike and A.E. Ugbogu, 2010. Effect of mining operations on the physicochemical properties and microbial diversity of soil from Ishiagu, Ebonyi State, Nigeria. J. Applied Environ. Sci., 6: 46-51.
  71. Chinyere, G.C., E.I. Akubugwo, I.C. Nwaukwa and A.E. Ugbogu, 2009. Nutritive value of Lagenaria sphaerica seed (Wild Bottle Gourds) from South-Eastern Nigeria. Pak. J. Nutr., 8: 384-387.
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  72. Akubugwo, E.I., O.C. Ugbogu, I.A. Muoha and A.E. Ugbogu, 2009. Impact of palm oil mill effluent (POME) on soils in Isialangwa, Abia State, Nigeria. Environ. Ecol., 27: 1677-1680.
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  73. Akubugwo, E.I., G.C. Ogbuji, G.C. Chinyere and A.E. Ugbogu, 2009. Physicochemical properties and enzyme activity studies in a refined oil contaminated soil in Isiukwuato, Abia State Nigeria. J. Nig. Soc. Exp Bio., 21: 79-84.
  74. Akubugwo, I.E., N.A. Obasi, G.C. Chinyere and A.E. Ugbogu, 2008. Mineral and phytochemical contents in leaves of Amaranthus hybridus L. and Solanum nigrum L. subjected to different processing methods. Afr. J. Biochem. Res., 2: 40-44.
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  75. Akubugwo, I.E., G.C. Chinyere and A.E. Ugbogu, 2008. Comparative studies on oils from some common plant seeds in Nigeria. Pak. J. Nutr., 7: 570-573.
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  76. Akubugwo, I.E., N.A. Obasi, G.C. Chinyere and A.E. Ugbogu, 2007. Nutritional and chemical value of Amaranthus hybridus L. leaves from Afikpo, Nigeria. Afr. J. Biotechnol., 6: 2833-2839.
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  77. Akubugwo, I.E. and A.E. Ugbogu, 2007. Physicochemical studies on oils from five selected Nigerian plant seeds. Pak. J. Nutr., 6: 75-78.
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  78. Agbafor, K.N., I.E. Akubugwo and A.E. Ugbogu, 2007. Toxicological evaluation of Okposi and Uburu salt Lake, Nigeria. Int. J. Biotechhnol. Allied Sci., 2: 186-189.