Jai-Sing Yang
My Social Links

Jai-Sing Yang




Share this Profile

Area of Interest:

Area of Interest
100%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Yang, J.S., J.H. Chiang, S. Tsai, Y.M. Hsu, D.T. Bau, K.H. Lee and F.J. Tsai, 2020. In silico De novo curcuminoid derivatives from the compound library of natural products research laboratories inhibit COVID-19 3CLpro activity. Nat. Prod. Commun., 10.1177/1934578x20953262.
    CrossRef  |  Direct Link  |  
  2. Chen, C., J.S. Yang, C.C. Lu, Y.J. Chiu and H.C. Chen et al., 2020. Effect of quercetin on dexamethasone-induced C2C12 skeletal muscle cell injury. Molecules, 10.3390/molecules25143267.
    CrossRef  |  Direct Link  |  
  3. Yu, E.Y.Y., F.S. Yang, Y.J. Chiu, F.J. Tsai, C.C. Lu and J.S. Yang, 2018. Late onset of biliopleural fistula following percutaneous transhepatic biliary drainage: a case report. BioMed., 10.1051/bmdcn/2018080106.
    CrossRef  |  Direct Link  |  
  4. Yang, J.S., Y.R. Peng, S.C. Tsai, Y.S. Tyan and C.C. Lu et al., 2018. The molecular mechanism of contrast-induced nephropathy (CIN) and its link to in vitro studies on iodinated contrast media (CM). BioMedicine, 10.1051/bmdcn/2018080101.
    CrossRef  |  Direct Link  |  
  5. Yang, J., C. Wang, C. Su, H. Ho, C. Chang, C. Chou and Y. Hsu, 2018. Eudesmin attenuates Helicobacter pylori-induced epithelial autophagy and apoptosis and leads to eradication of H. pylori infection. Exp. Ther. Med., 15: 2388-2396.
    CrossRef  |  Direct Link  |  
  6. Wu, H., C. Horng, S. Tsai, Y. Lee and S. Hsu et al., 2018. Relaxant and vasoprotective effects of ginger extracts on porcine coronary arteries. Int. J. Mol. Med., 41: 2420-2428.
    CrossRef  |  Direct Link  |  
  7. Chin, H.K., C.T. Horng, Y.S. Liu, C.C. Lu and C.Y. Su et al., 2018. Kaempferol inhibits angiogenic ability by targeting VEGF receptor-2 and downregulating the PI3K/AKT, MEK and ERK pathways in VEGF-stimulated human umbilical vein endothelial cells. Oncol. Rep., 39: 2351-2357.
    CrossRef  |  Direct Link  |  
  8. Chang, H.P., C.C. Lu, J.H. Chiang, F.J. Tsai and Y.N. Juan et al., 2018. Pterostilbene modulates the suppression of multidrug resistance protein 1 and triggers autophagic and apoptotic mechanisms in cisplatin-resistant human oral cancer CAR cells via AKT signaling. Int. J. Oncol., 52: 1504-1514.
    CrossRef  |  Direct Link  |  
  9. C.C. Lu, W.K. Chen, J.H. Chiang, Y.F. Tsai and Y.N. Juan et al., 2018. cDNA microarray analysis and influx transporter OATP1B1 in liver cells after exposure to gadoxetate disodium, a gadolinium-based contrast agent in MRI liver imaging. In Vivo, 32: 677-684.
    CrossRef  |  Direct Link  |  
  10. Yang, J.S., C.C. Lu, S.C. Kuo, Y.M. Hsu and S.C. Tsai et al., 2017. Autophagy and its link to type II diabetes mellitus. BioMedicine, 10.1051/bmdcn/2017070201.
    CrossRef  |  Direct Link  |  
  11. Yang, J.S., C.A. Lin, C.C. Lu, Y.F. Wen, F.J. Tsai and S.C. Tsai, 2017. Carboxamide analog ITR-284 evokes apoptosis and inhibits migration ability in human lung adenocarcinoma A549 cells. Oncol. Rep., 37: 1786-1792.
    CrossRef  |  Direct Link  |  
  12. Tsai, S.C., S.F. Huang, J.H. Chiang, Y.F. Chen and C.C. Huang et al., 2017. The differential regulation of micrornas is associated with oral cancer. Oncol. Rep., 38: 1613-1620.
    CrossRef  |  Direct Link  |  
  13. Lin, M., J. Yang, C. Lu, C. Lin, S. Kuo, F. Tsai and M. Lee, 2017. 2-phenyl-4-quinolone (YT-1) induces g2/M phase arrest and an intrinsic apoptotic mechanism in human leukemia cells. Oncol. Rep., 10.3892/or.2017.6170.
    CrossRef  |  Direct Link  |  
  14. Lee, M.R., C. Lin, C.C. Lu, S.C. Kuo and J.W. Tsao et al., 2017. YC-1 induces G0/G1 phase arrest and mitochondria-dependent apoptosis in cisplatin-resistant human oral cancer CAR cells BioMedicine, 10.1051/bmdcn/2017070205.
    CrossRef  |  Direct Link  |  
  15. Horng, C.T., H.C. Wu, N.N. Chiang, C.F. Lee and Y.S. Huang et al., 2017. Inhibitory effect of burdock leaves on elastase and tyrosinase activity. Exp. Ther. Med., 14: 3247-3252.
    CrossRef  |  Direct Link  |  
  16. Chiu, Y.J., J.S. Yang, H.S. Hsu, C.H. Tsai and H. Ma, 2017. Adipose-derived stem cell conditioned medium attenuates cisplatin-triggered apoptosis in tongue squamous cell carcinoma. Oncol. Rep., 10.3892/or.2017.6126.
    CrossRef  |  Direct Link  |  
  17. Chien, K., C. Horng, Y. Huang, Y. Hsieh and C. Wang et al., 2017. Effects of lycium barbarum (goji berry) on dry eye disease in rats. Mol. Med. Rep., 17: 809-818.
    CrossRef  |  Direct Link  |  
  18. Chang, Y.C., N. Tien, J.S. Yang, C.C. Lu, F.J. Tsai, T.J. Huang and I.K. Wang, 2017. Class 1 integrons and plasmid-mediated multiple resistance genes of the Campylobacter species from pediatric patient of a university hospital in Taiwan. Gut Pathog., 10.1186/s13099-017-0199-4.
    CrossRef  |  Direct Link  |  
  19. Chang, L.C., M.T. Hsieh, J.S. Yang, C.C. Lu and F.J. Tsai et al., 2017. Effect of bis(hydroxymethyl) alkanoate curcuminoid derivative MTH-3 on cell cycle arrest, apoptotic and autophagic pathway in triple-negative breast adenocarcinoma MDA-MB-231 cells: an in vitro study. Int. J. Oncol., 52: 67-76.
    CrossRef  |  Direct Link  |  
  20. Chang, C.H., C.Y. Lee, C.C. Lu, F.J. Tsai and Y.M. Hsu et al., 2017. Resveratrol-induced autophagy and apoptosis in cisplatin-resistant human oral cancer CAR cells: A key role of AMPK and Akt/mTOR signaling. Int. J. Oncol., 50: 873-882.
    CrossRef  |  Direct Link  |  
  21. Tsai, Y.F., C.W. Huang, J.H. Chiang, F.J. Tsai and Y.M. Hsu et al., 2016. Gadolinium chloride elicits apoptosis in human osteosarcoma U-2 OS cells through extrinsic signaling, intrinsic pathway and endoplasmic reticulum stress. Oncol. Rep., 36: 3421-3426.
    CrossRef  |  Direct Link  |  
  22. Seo, D., N.Y. Kim, J.A. Lee, K.R. Han, G.H. Hur, J.M. Yang and S. Shin, 2016. Protection against lethal vaccinia virus infection in mice using an siRNA targeting the A5R gene. Antiviral Ther., 21: 397-404.
    CrossRef  |  Direct Link  |  
  23. Lin, C.F., J.S. Yang, C. Lin, F.J. Tsai, C.C. Lu and M.R. Lee, 2016. CCY-1a-E2 induces G2/M phase arrest and apoptotic cell death in HL-60 leukemia cells through cyclin-dependent kinase 1 signaling and the mitochondria-dependent caspase pathway. Oncol. Rep., 36: 1633-1639.
    CrossRef  |  Direct Link  |  
  24. Lee, C.F., J.S. Yang, F.J. Tsai, N.N. Chiang and C.C. Lu et al., 2016. Kaempferol induces ATM/p53-mediated death receptor and mitochondrial apoptosis in human umbilical vein endothelial cells. Int. J. Oncol., 48: 2007-2014.
    CrossRef  |  Direct Link  |  
  25. Ho, T.J., S.J. Jiang, G.H. Lin, T.S. Li and L.M. Yiin et al., 2016. The in vitro and in vivo wound healing properties of the Chinese herbal medicine “jinchuang ointment”. Evidence-Based Compl. Alt. Med., 10.1155/2016/1654056.
    CrossRef  |  Direct Link  |  
  26. Chen, S.Y., Y.M. Hsu, Y.J. Lin, Y.C. Huang and C.J. Chen et al., 2016. Current concepts regarding developmental mechanisms in diabetic retinopathy in Taiwan. BioMedicine, 10.7603/s40681-016-0007-3.
    CrossRef  |  Direct Link  |  
  27. Kim, N.Y., D.S. Chang, Y. Kim, C.H. Kim, G.H. Hur, J.M. Yang and S. Shin, 2015. Enhanced immune response to DNA vaccine encoding Bacillus anthracis PA-D4 protects mice against anthrax spore challenge. PLoS ONE, 10.1371/journal.pone.0139671.
    CrossRef  |  Direct Link  |  
  28. Horng, C.T., J.S. Yang, J.H. Chiang, C.C. Lu, C.F. Lee, N.N. Chiang and F.A. Chen, 2015. Inhibitory effects of tetrandrine on epidermal growth factor-induced invasion and migration in HT29 human colorectal adenocarcinoma cells. Mol. Med. Rep., 13: 1003-1009.
    CrossRef  |  Direct Link  |  
  29. Wang, M.J., Y.Q. Liu, L.C. Chang, C.Y. Wang and Y.L. Zhao et al., 2014. Design, synthesis, mechanisms of action, and toxicity of novel 20(s)-sulfonylamidine derivatives of camptothecin as potent antitumor agents. J. Medic. Chem., 57: 6008-6018.
    CrossRef  |  Direct Link  |  
  30. Lu, C.C., J.S. Yang, J.H. Chiang, M.J. Hour, K.L. Lin, T.H. Lee and J.G. Chung, 2014. Cell death caused by quinazolinone HMJ-38 challenge in oral carcinoma CAL 27 cells: dissections of endoplasmic reticulum stress, mitochondrial dysfunction and tumor xenografts. Biochim. Biophys. Acta (BBA) General Subjects, 1840: 2310-2320.
    CrossRef  |  Direct Link  |  
  31. Lu, C.C., H.P. Chen, J.H. Chiang, Y.A. Jin and S.C. Kuo et al., 2014. Quinazoline analog HMJ-30 inhibits angiogenesis: involvement of endothelial cell apoptosis through ROS-JNK-mediated death receptor 5 signaling. Oncol. Rep., 32: 597-606.
    CrossRef  |  Direct Link  |  
  32. Kuo, Y.J., J.S. Yang, C.C. Lu, S.y. Chiang, J.G. Lin and J.G. Chung, 2014. Ethanol extract of Hedyotis diffusa willd upregulates G0/G1 phase arrest and induces apoptosis in human leukemia cells by modulating caspase cascade signaling and altering associated genes expression was assayed by cDNA microarray. Environ. Toxicol., 30: 1162-1177.
    CrossRef  |  Direct Link  |  
  33. King, Y.A., Y.J. Chiu, H.P. Chen, D.H. Kuo, C.C. Lu and J.S. Yang, 2014. Endoplasmic reticulum stress contributes to arsenic trioxide-induced intrinsic apoptosis in human umbilical and bone marrow mesenchymal stem cells. Environ. Toxicol., 31: 314-328.
    CrossRef  |  Direct Link  |  
  34. Hsieh, M.T., H.P. Chen, C.C. Lu, J.H. Chiang and T.S. Wu et al., 2014. The novel pterostilbene derivative ANK-199 induces autophagic cell death through regulating pi3 kinase class iii/beclin 1/atg-related proteins in cisplatin-resistant CAR human oral cancer cells. Int. J. Oncol., 45: 782-794.
    CrossRef  |  Direct Link  |  
  35. Chen, Y.L., F.S. Chueh, J.S. Yang, S.C. Hsueh and C.C. Lu et al., 2014. Antitumor effects with apoptotic death in human promyelocytic leukemia HL-60 cells and suppression of leukemia xenograft tumor growth by irinotecan HCl. Environ. Toxicol., 30: 803-815.
    CrossRef  |  Direct Link  |  
  36. Chen, Y.F., A.L. Shiau, S.H. Wang, J.S. Yang, S.J. Chang, C.L. Wu and T.S. Wu, 2014. Zhankuic acid a isolated fromtaiwanofungus camphoratusis a novel selective TLR4/MD-2 antagonist with anti-inflammatory properties. J. Immunol., 192: 2778-2786.
    CrossRef  |  Direct Link  |  
  37. Yang, J.L., J.H. Lin, S.W. Weng, J.C. Chen and J.S. Yang et al., 2013. Crude extract of Euphorbia formosana inhibits the migration and invasion of DU145 human prostate cancer cells: The role of matrix metalloproteinase-2/9 inhibition via the MAPK signaling pathway. Mol. Med. Rep., 7: 1403-1408.
    CrossRef  |  Direct Link  |  
  38. Wu, K.C., S.T. Yang, S.C. Hsu, J.H. Chiang and T.C. Hsia et al., 2013. Propofol induces DNA damage in mouse leukemic monocyte macrophage RAW264.7 cells. Oncol. Rep., 30: 2304-2310.
    CrossRef  |  Direct Link  |  
  39. Peng, S.F., C.Y. Lee, M.J. Hour, S.C. Tsai and D.H. Kuo et al., 2013. Curcumin-loaded nanoparticles enhance apoptotic cell death of U2OS human osteosarcoma cells through the Akt-Bad signaling pathway. Int. J. Oncol., 44: 238-246.
    CrossRef  |  Direct Link  |  
  40. Ma, Y.S., S.C. Hsu, S.W. Weng, C.C. Yu and J.S. Yang et al., 2013. Crude extract of Rheum palmatum L induced cell death in LS1034 human colon cancer cells acts through the caspase-dependent and -independent pathways. Environ. Toxicol., 29: 969-980.
    CrossRef  |  Direct Link  |  
  41. Lin, Y.T., A.C. Huang, C.L. Kuo, J.S. Yang and Y.H. Lan et al., 2013. Induction of cell cycle arrest and apoptosis in human osteosarcoma U-2 OS Cells by Solanum lyratum extracts. Nutr. Cancer, 65: 469-479.
    CrossRef  |  Direct Link  |  
  42. Lin, Y.C., J.Y. Tsai, J.S. Yang, Y.H. Lee and E. Hamel et al., 2013. The novel synthetic compound 6-acetyl-9-(3,4,5-trimethoxybenzyl)-9h-pyrido[2,3-b]indole induces mitotic arrest and apoptosis in human COLO 205 cells. Int. J. Oncol., 43: 1596-1606.
    CrossRef  |  Direct Link  |  
  43. Lin, C., S.C. Tsai, M.T. Tseng, S.F. Peng and S.C. Kuo et al., 2013. AKT serine/threonine protein kinase modulates baicalin-triggered autophagy in human bladder cancer T24 cells. Int. J. Oncol., 42: 993-1000.
    CrossRef  |  Direct Link  |  
  44. Liao, Y.R., C.C. Lu, K.C. Lai, J.S. Yang and S.C. Kuo et al., 2013. The novel carboxamide analog ITR-284 induces caspase-dependent apoptotic cell death in human hepatocellular and colorectal cancer cells. Mol. Med. Rep., 7: 1539-1544.
    CrossRef  |  Direct Link  |  
  45. Lai, K.C., C.C. Lu, Y.J. Tang, J.H. Chiang and D.H. Kuo et al., 2013. Allyl isothiocyanate inhibits cell metastasis through suppression of the mapk pathways in epidermal growth factor-stimulated ht29 human colorectal adenocarcinoma cells. Oncol. Rep., 31: 189-196.
    CrossRef  |  Direct Link  |  
  46. Hung, F.M., Y.L. Chen, A.C. Huang, Y.P. Hsiao and J.S. Yang et al., 2013. Triptolide induces S phase arrest via the inhibition of cyclin E and CDC25A and triggers apoptosis via caspase- and mitochondrial-dependent signaling pathways in A375.S2 human melanoma cells. Oncol. Rep., 29: 1053-1060.
    CrossRef  |  Direct Link  |  
  47. Huang, Y.P., C.H. Ni, C.C. Lu, J.H. Chiang and J.S. Yang et al., 2013. Suppressions of migration and invasion by Cantharidin in TSGH-8301 human bladder carcinoma cells through the inhibitions of matrix metalloproteinase-2/-9 signaling. Evidence-Based Compl. Alt. Med., 10.1155/2013/190281.
    CrossRef  |  Direct Link  |  
  48. Huang, W.W., S.C. Tsai, S.F. Peng, M.W. Lin and J.H. Chiang et al., 2013. Kaempferol induces autophagy through AMPK and AKT signaling molecules and causes G2/M arrest via downregulation of CDK1/cyclin B in SK-HEP-1 human hepatic cancer cells. Int. J. Oncol., 42: 2069-2077.
    CrossRef  |  Direct Link  |  
  49. Huang, S.H., M.H. Hsu, S.C. Hsu, J.S. Yang and W.W. Huang et al., 2013. Phenethyl isothiocyanate triggers apoptosis in human malignant melanoma A375.S2 cells through reactive oxygen species and the mitochondria-dependent pathways. Hum. Exp. Toxicol., 33: 270-283.
    CrossRef  |  Direct Link  |  
  50. Huang, A.C., J.C. Lien, M.W. Lin, J.S. Yang, P.P. Wu, S.J. Chang and T.Y. Lai, 2013. Tetrandrine induces cell death in SAS human oral cancer cells through caspase activation-dependent apoptosis and LC3-I and LC3-II activation-dependent autophagy. Int. J. Oncol., 43: 485-494.
    CrossRef  |  Direct Link  |  
  51. Ho, C.C., A.C. Huang, C.S. Yu, J.C. Lien and S.H. Wu et al., 2013. Ellagic acid induces apoptosis in TSGH8301 human bladder cancer cells through the endoplasmic reticulum stress- and mitochondria-dependent signaling pathways. Environ. Toxicol., 10.1002/tox.21857.
    CrossRef  |  Direct Link  |  
  52. Chiu, T.H., K.Y. Lan, M.D. Yang, J.J. Lin and T.C. Hsia et al., 2013. Diallyl sulfide promotes cell-cycle arrest through the p53 expression and triggers induction of apoptosis via caspase- and mitochondria-dependent signaling pathways in human cervical cancer cCa Ski cells. Nutr. Cancer, 65: 505-514.
    CrossRef  |  Direct Link  |  
  53. Chiang, J.H., J.S. Yang, C.C. Lu, M.J. Hour, S.J. Chang, T.H. Lee and J.G. Chung, 2013. Newly synthesized quinazolinone HMJ-38 suppresses angiogenetic responses and triggers human umbilical vein endothelial cell apoptosis through p53-modulated Fas/death receptor signaling. Toxicol. Appl. Pharmacol., 269: 150-162.
    CrossRef  |  Direct Link  |  
  54. Chiang, J.H., J.S. Yang, C.C. Lu, M.J. Hour and K.C. Liu et al., 2013. Effect of DNA damage response by quinazolinone analogue HNJ-38 on human umbilical vein endothelial cells. Hum. Exp. Toxicol., 33: 590-601.
    CrossRef  |  Direct Link  |  
  55. Cheng, Y.Y., C.Y. Liu, M.T. Tsai, H.Y. Lin and J.S. Yang et al., 2013. Design, synthesis, and mechanism of action of 2-(3-hydroxy-5-methoxyphenyl)-6-pyrrolidinylquinolin-4-one as a potent anticancer lead. Bioorg. Medic. Chem. Lett., 23: 5223-5227.
    CrossRef  |  Direct Link  |  
  56. Chen, Y.F., J.S. Yang, W.S. Chang, S.C. Tsai, S.F. Peng and Y.R. Zhou, 2013. Houttuynia cordata Thunb extract modulates G0/G1 arrest and Fas/CD95-mediated death receptor apoptotic cell death in human lung cancer A549 cells. J. Biomed. Sci., 10.1186/1423-0127-20-18.
    CrossRef  |  Direct Link  |  
  57. Chen, H.J., Y.L. Jiang, C.M. Lin, S.C. Tsai and S.F. Peng et al., 2013. Dual inhibition of EGFR and c-Met kinase activation by MJ-56 reduces metastasis of HT29 human colorectal cancer cells. Int. J. Oncol., 43: 141-150.
    CrossRef  |  Direct Link  |  
  58. Chen, H.J., C.M. Lin, C.Y. Lee, N.C. Shih, S. Amagaya, Y.C. Lin and J.S. Yang, 2013. Phenethyl isothiocyanate suppresses EGF-stimulated SAShuman oral squamous carcinoma cell invasion by targeting EGF receptor signaling. Int. J. Oncol., 43: 629-637.
    CrossRef  |  Direct Link  |  
  59. Chen, H.J., C.M. Lin, C.Y. Lee, N.C. Shih and S.F. Peng et al., 2013. Kaempferol suppresses cell metastasis via inhibition of the ERK-p38-JNK and AP-1 signaling pathways in U-2 OS human osteosarcoma cells. Oncol. Rep., 30: 925-932.
    CrossRef  |  Direct Link  |  
  60. Chang, P.Y., S.F. Peng, C.Y. Lee, C.C. Lu and S.C. Tsai et al., 2013. Curcumin-loaded nanoparticles induce apoptotic cell death through regulation of the function of MDR1 and reactive oxygen species in cisplatin-resistant CAR human oral cancer cells. Int. J. Oncol., 43: 1141-1150.
    CrossRef  |  Direct Link  |  
  61. Yu, C.S., A.C. Huang, K.C. Lai, Y.P. Huang, M.W. Lin, J.S. Yang and Chung, 2012. Diallyl trisulfide induces apoptosis in human primary colorectal cancer cells. Oncol. Rep., 28: 949-954.
    CrossRef  |  Direct Link  |  
  62. Yu, C.C., F.Y. Ko, C.S. Yu, C.C. Lin and Y.P. Huang et al., 2012. Norcantharidin triggers cell death and DNA damage through S-phase arrest and ROS-modulated apoptotic pathways in TSGH 8301 human urinary bladder carcinoma cells. Int. J. Oncol., 41: 1050-1060.
    CrossRef  |  Direct Link  |  
  63. Yang, J.S., C.C. Wu, C.L. Kuo, Y.H. Lan and C.C. Yeh et al., 2012. Solanum lyratum extracts induce extrinsic and intrinsic pathways of apoptosis in WEHI-3 murine leukemia cells and inhibit allograft tumor. Evidence-Based Compl. Alt. Med., 10.1155/2012/254960.
    CrossRef  |  Direct Link  |  
  64. Wu, R.C., C.S. Yu, K.C. Liu, H.Y. Huang and S.W. Ip et al., 2012. Citosol (thiamylal sodium) triggers apoptosis and affects gene expressions of murine leukemia RAW 264.7 cells. Hum. Exp. Toxicol., 31: 771-779.
    CrossRef  |  Direct Link  |  
  65. Tsai, S.C., W.W. Huang, W.C. Huang, C.C. Lu and J.H. Chiang et al., 2012. ERK-modulated intrinsic signaling and G2/M phase arrest contribute to the induction of apoptotic death by allyl isothiocyanate in MDA-MB-468 human breast adenocarcinoma cells. Int. J. Oncol., 41: 2065-2072.
    CrossRef  |  Direct Link  |  
  66. Tsai, S.C., J.S. Yang, S.F. Peng, C.C. Lu and J.H. Chiang et al., 2012. Bufalin increases sensitivity to AKT/mTOR-induced autophagic cell death in SK-HEP-1 human hepatocellular carcinoma cells. Int. J. Oncol., 41: 1431-1442.
    CrossRef  |  Direct Link  |  
  67. Tsai, S.C., C.C. Lu, C.Y. Lee, Y.C. Lin and J.G. Chung et al., 2012. AKT serine/threonine protein kinase modulates bufalin-triggered intrinsic pathway of apoptosis in CAL 27 human oral cancer cells. Int. J. Oncol., 41: 1683-1692.
    CrossRef  |  Direct Link  |  
  68. Ni, C.H., P.Y. Chen, H.F. Lu, J.S. Yang and H.Y. Huang et al., 2012. Chrysophanol-induced necrotic-like cell death through an impaired mitochondrial ATP synthesis in Hep3B human liver cancer cells. Arch. Pharm. Res., 35: 887-895.
    CrossRef  |  Direct Link  |  
  69. Ni, C.H., C.S. Yu, H.F. Lu, J.S. Yang and H.Y. Huang et al., 2012. Chrysophanol-induced cell death (necrosis) in human lung cancer A549 cells is mediated through increasing reactive oxygen species and decreasing the level of mitochondrial membrane potential. Environ. Toxicol. 10.1002/tox.21801.
    CrossRef  |  
  70. Ma, Y.S., S.W. Weng, M.W. Lin, C.C. Lu and J.H. Chiang et al., 2012. Antitumor effects of emodin on LS1034 human colon cancer cells in vitro and in vivo: Roles of apoptotic cell death and LS1034 tumor xenografts model. Food Chem. Toxicol., 50: 1271-1278.
    CrossRef  |  Direct Link  |  
  71. Lu, H.F., W.L. Tung, J.S. Yang, F.M. Huang and C.S. Lee et al., 2012. In vitro suppression of growth of murine WEHI-3 leukemia cells and in vivo promotion of phagocytosis in a leukemia mice model by Indole-3-carbinol. J. Agric. Food Chem., 60: 7634-7643.
    CrossRef  |  Direct Link  |  
  72. Lu, C.C., J.S. Yang, J.H. Chiang, M.J. Hour and K.L. Lin et al., 2012. Novel quinazolinone MJ-29 triggers endoplasmic reticulum stress and intrinsic apoptosis in murine leukemia WEHI-3 cells and inhibits leukemic mice. PLoS ONE, 10.1371/journal.pone.0036831.
    CrossRef  |  Direct Link  |  
  73. Liu, K.C., C.Y. Yen, R.S.C. Wu, J.S. Yang and H.F. Lu et al., 2012. The roles of endoplasmic reticulum stress and mitochondrial apoptotic signaling pathway in quercetin-mediated cell death of human prostate cancer PC-3 cells. Environ. Toxicol., 29: 428-439.
    CrossRef  |  Direct Link  |  
  74. Liu, C.Y., J.S. Yang, S.M. Huang, J.H. Chiang and M.H. Chen et al., 2012. Smh-3 induces G2/M arrest and apoptosis through calcium-mediated endoplasmic reticulum stress and mitochondrial signaling in human hepatocellular carcinoma Hep3B cells. Oncol. Rep., 29: 751-762.
    CrossRef  |  Direct Link  |  
  75. Lin, J.G., M.J. Fan, N.Y. Tang, J.S. Yang and T.C. Hsia et al., 2012. An extract of Agaricus blazei murill administered orally promotes immune responses in murine leukemia BALB/c mice in vivo. Integr. Cancer Ther., 11: 29-36.
    CrossRef  |  Direct Link  |  
  76. Lin, C.C., Y.J. Chuang, C.C. Yu, J.S. Yang and C.C. Lu et al., 2012. Apigenin induces apoptosis through mitochondrial dysfunction in U-2 S human osteosarcoma cells and inhibits osteosarcoma xenograft tumor growth in vivo. J. Agric. Food Chem., 60: 11395-11402.
    CrossRef  |  Direct Link  |  
  77. Lin, C., J.S. Yang, S.C. Tsai, C.F. Lin and M.R. Lee, 2012. In vivo evaluation of the synthesized novel 2-benzyloxybenzaldehyde analog CCY-1a-E2 for the treatment of leukemia in the BALB/c mouse WEHI-3 allograft model. Oncol. Lett., 5: 777-782.
    CrossRef  |  Direct Link  |  
  78. Liao, C.L., K.C. Lai, A.C. Huang, J.S. Yang and J.J. Lin et al., 2012. Gallic acid inhibits migration and invasion in human osteosarcoma U-2 OS cells through suppressing the matrix metalloproteinase-2/-9, protein kinase b (PKB) and PKC signaling pathways. Food Chem. Toxicol., 50: 1734-1740.
    CrossRef  |  Direct Link  |  
  79. Lee, C.Y., Y.S. Chien, T.H. Chiu, W.W. Huang, C.C. LU, J.H. Chiang and J.S. Yang, 2012. Apoptosis triggered by vitexin in U937 human leukemia cells via a mitochondrial signaling pathway. Oncol. Rep., 28: 1883-1888.
    CrossRef  |  Direct Link  |  
  80. Lan, Y.H., J.H. Chiang, W.W. Huang, C.C. Lu and J.G. Chung et al., 2012. Activations of both extrinsic and intrinsic pathways in HCT 116 human colorectal cancer cells contribute to apoptosis through p53-mediated ATM/Fas signaling by Emilia sonchifolia extract, a folklore medicinal plant. Evidence-Based Compl. Alt. Med., 10.1155/2012/178178.
    CrossRef  |  Direct Link  |  
  81. Lai, K.C., C.L. Kuo, H.C. Ho, J.S. Yang and C.Y. Ma et al., 2012. Diallyl sulfide, diallyl disulfide and diallyl trisulfide affect drug resistant gene expression in colo 205 human colon cancer cells in vitro and in vivo. Phytomedicine, 19: 625-630.
    CrossRef  |  Direct Link  |  
  82. JI, B.C., C.C. Yu, S.T. Yang, T.C. Hsia and J.S. Yang et al., 2012. Induction of DNA damage by deguelin is mediated through reducing DNA repair genes in human non-small cell lung cancer nci-h460 cells. Oncol. Rep., 27: 959-964.
    CrossRef  |  Direct Link  |  
  83. Huang, W.Y., C.L. Yeh, J.H. Lin, J.S. Yang, T.H. Ko and Y.H. Lin, 2012. Development of fibroblast culture in three-dimensional activated carbon fiber-based scaffold for wound healing. J. Mater. Sci.: Mater. Med., 23: 1465-1478.
    CrossRef  |  Direct Link  |  
  84. Huang, W.W., J.S. Yang, S.J. Pai, P.P. Wu and S.J. Chang et al., 2012. Bufalin induces G0/G1 phase arrest through inhibiting the levels of cyclin D, cyclin E, CDK2 and CDK4, and triggers apoptosis via mitochondrial signaling pathway in T24 human bladder cancer cells Mutat. Res./Fundam. Mol. Mech. Mutagen., 732: 26-33.
    CrossRef  |  Direct Link  |  
  85. Huang, W.W., J.S. Yang, M.W. Lin, P.Y. Chen and S.M. Chiou et al., 2012. Cucurbitacin e induces g2/m phase arrest through STAT3/p53/p21 signaling and provokes apoptosisviafas/CD95 and mitochondria-dependent pathways in human bladder cancer T24 cells. Evidence-Based Compl. Alt. Med., 10.1155/2012/952762.
    CrossRef  |  Direct Link  |  
  86. Huang, S.H., L.W. Wu, A.C. Huang, C.C. Yu and J.C. Lien et al., 2012. Benzyl isothiocyanate (BITC) induces G2/M phase arrest and apoptosis in human melanoma A375.S2 cells through reactive oxygen species (ROS) and both mitochondria-dependent and death receptor-mediated multiple signaling pathways. J. Agric. Food Chem., 60: 665-675.
    CrossRef  |  Direct Link  |  
  87. Hsiao, Y.P., C.S. Yu, C.C. Yu, J.S. Yang and J.H. Chiang et al., 2012. Triggering apoptotic death of human malignant melanoma A375.S2 cells by bufalin: involvement of caspase cascade-dependent and independent mitochondrial signaling pathways. Evidence-Based Compl. Alt. Med., 10.1155/2012/591241.
    CrossRef  |  Direct Link  |  
  88. Chueh, F.S., Y.T. Hsiao, S.J. Chang, P.P. Wu and J.S. Yang et al., 2012. Glycyrrhizic acid induces apoptosis in WEHI-3 mouse leukemia cells through the caspase- and mitochondria-dependent pathways. Oncol. Rep., 28: 2069-2076.
    CrossRef  |  Direct Link  |  
  89. Chueh, F.S., Y.L. Chen, S.C. Hsu, J.S. Yang and S.C. Hsueh et al., 2012. Triptolide induced DNA damage in A375.S2 human malignant melanoma cells is mediated via reduction of DNA repair genes. Oncol. Rep., 29: 613-618.
    CrossRef  |  Direct Link  |  
  90. Chiou, S.M., C.H. Chiu, S.T. Yang, J.S. Yang and H.Y. Huang et al., 2012. Danthron triggers ROS and mitochondria-mediated apoptotic death in C6 rat glioma cells through caspase cascades, apoptosis-inducing factor and endonuclease G multiple signaling. Neurochem. Res., 37: 1790-1800.
    CrossRef  |  Direct Link  |  
  91. Cheng, Y.Y., J.S. Yang, S.C. Tsai, C.C. Liaw and J.G. Chung et al., 2012. The newly synthesized 2-(3-hydroxy-5-methoxyphenyl)-6,7-methylenedioxyquinolin-4-one triggers cell apoptosis through induction of oxidative stress and upregulation of the p38 MAPK signaling pathway in HL-60 human leukemia cells. Oncol. Rep., 28: 1482-1490.
    CrossRef  |  Direct Link  |  
  92. Chen, P.Y., K.C. Lin, J.P. Lin, N.Y. Tang, J.S. Yang, K.W. Lu and J.G. Chung, 2012. Phenethyl isothiocyanate (PEITC) inhibits the growth of human oral squamous carcinoma HSC-3 cells through G0/G1 phase arrest and mitochondria-mediated apoptotic cell death. Evidence-Based Compl. Alt. Med., 10.1155/2012/718320.
    CrossRef  |  Direct Link  |  
  93. Chang, C.M., P.Y. Chang, M.G. Tu, C.C. Lu and S.C. Kuo et al., 2012. Epigallocatechin gallate sensitizes CAL-27 human oral squamous cell carcinoma cells to the anti-metastatic effects of gefitinib (Iressa) via synergistic suppression of epidermal growth factor receptor and matrix metalloproteinase-2. Oncol. Rep., 28: 1799-1807.
    CrossRef  |  Direct Link  |  
  94. Alam, I., J.H. Lee, K.J. Cho, K.R. Han, J.M. Yang, M.S. Chung and K.H. Kim, 2012. Crystal structures of murine norovirus-1 RNA-dependent RNA polymerase in complex with 2-thiouridine or ribavirin. Virology, 426: 143-151.
    CrossRef  |  Direct Link  |  
  95. Yu, F.S., J.S. Yang, C.S. Yu, J.H. Chiang and C.C. Lu et al., 2011. Safrole suppresses murine myelomonocytic leukemia WEHI-3 cells in vivo, and stimulates macrophage phagocytosis and natural killer cell cytotoxicity in leukemic mice. Environ. Toxicol., 28: 601-608.
    CrossRef  |  Direct Link  |  
  96. Yu, F.S., A.C. Huang, J.S. Yang, C.S. Yu and C.C. Lu et al., 2011. Safrole induces cell death in human tongue squamous cancer SCC-4 cells through mitochondria-dependent caspase activation cascade apoptotic signaling pathways. Environ. Toxicol., 10.1002/tox.20658.
    CrossRef  |  
  97. Wu, R.S.C., K.C. Liu, N.Y. Tang, H.K. Chung, S.W. Ip, J.S. Yang and J.G. Chung, 2011. cDNA Microarray analysis the gene expression of murine leukemia RAW 264.7 cells after exposure to propofol. Environ. Toxicol., 10.1002/tox.20742.
    CrossRef  |  
  98. Wu, C.L., A.C. Huang, J.S. Yang, C.L. Liao and H.F. Lu et al., 2011. Benzyl isothiocyanate (BITC) and phenethyl isothiocyanate (PEITC)-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of caspase-3, mitochondria dysfunction and nitric oxide (NO) in human osteogenic sarcoma U-2 OS cells. J. Orthop. Res., 29: 1199-1209.
    CrossRef  |  PubMed  |  Direct Link  |  
  99. Tsou, M.F., N. Tien, C.C. Lu, J.H. Chiang and J.S. Yang et al., 2011. Phenethyl Isothiocyanate (PEITC) promotes immune responses in normal BALB/c mice, inhibits murine leukemia WEHI-3 cells and stimulates immunomodulations in vivo. Environ. Toxicol., 10.1002/tox.20705.
    CrossRef  |  
  100. Ma, C.Y., W.T. Ji, F.S. Chueh, J.S. Yang, P.Y. Chen, C.C. Yu and J.G. Chung, 2011. Butein inhibits the migration and invasion of SK-HEP-1 human hepatocarcinoma cells through suppressing the ERK, JNK, P38, and UPA signaling multiple pathways. J. Agric. Food Chem., 59: 9032-9038.
    CrossRef  |  Direct Link  |  
  101. Lu, K.W., J.C. Chen, T.Y. Lai, J.S. Yang and S.W. Weng et al., 2011. Gypenosides suppress growth of human oral cancer SAS cells in vitro and in a murine xenograft model. Integr. Cancer Ther., 11: 129-140.
    CrossRef  |  Direct Link  |  
  102. Lo, C., T.Y. Lai, J.S. Yang, J.H. Yang and Y.S. Ma et al., 2011. Gallic acid inhibits the migration and invasion of A375.S2 human melanoma cells through the inhibition of matrix metalloproteinase-2 and ras. Melanoma Res., 21: 267-273.
    CrossRef  |  Direct Link  |  
  103. Liu, K.C., H.C. Ho, A.C. Huang, B.C. Ji and H.Y. Lin et al., 2011. Gallic acid provokes DNA damage and suppresses DNA repair gene expression in human prostate cancer PC-3 cells. Environ. Toxicol., 28: 579-587.
    CrossRef  |  Direct Link  |  
  104. Lin, J.P., J.S. Yang, J.J. Lin, K.C. Lai and H.F. Lu et al., 2011. Rutin inhibits human leukemia tumor growth in a murine xenograft model in vivo. Environ. Toxicol., 27: 480-484.
    CrossRef  |  Direct Link  |  
  105. Lai, K.C., S.C. Hsu, C.L. Kuo, J.S. Yang and C.Y. Ma et al., 2011. Diallyl sulfide, diallyl disulfide, and diallyl trisulfide inhibit migration and invasion in human colon cancer colo 205 cells through the inhibition of matrix metalloproteinase-2, -7, and -9 expressions. Environ. Toxicol., 28: 479-488.
    CrossRef  |  Direct Link  |  
  106. Ip, S.W., Y.L. Chu, C.S. Yu, P.Y. Chen and H.C. Ho et al., 2011. Bee venom induces apoptosis through intracellular Ca2+-modulated intrinsic death pathway in human bladder cancer cells. Int. J. Urol., 19: 61-70.
    CrossRef  |  Direct Link  |  
  107. Ip, S.W., S.Y. Wu, C.C. Yu, C.L. Kuo and C.S. Yu et al., 2011. Induction of apoptotic death by curcumin in human tongue squamous cell carcinoma SCC-4 cells is mediated through endoplasmic reticulum stress and mitochondria-dependent pathways. Cell Biochem. Funct., 29: 641-650.
    CrossRef  |  Direct Link  |  
  108. Ip, S.W., S.H. Lan, H.F. Lu, A.C. Huang and J.S. Yang et al., 2011. Capsaicin mediates apoptosis in human nasopharyngeal carcinoma NPC-TW 039 cells through mitochondrial depolarization and endoplasmic reticulum stress. Hum. Exp. Toxicol., 31: 539-549.
    CrossRef  |  Direct Link  |  
  109. Hung, F.M., Y.Y. Chuang, C.S. Lee, Y.L. Chen and J.S. Yang et al., 2011. Butylated hydroxyanisole affects immunomodulation and promotes macrophage phagocytosis in normal BALB/c mice. Mol. Med. Rep., 5: 683-687.
    CrossRef  |  Direct Link  |  
  110. Huang, A.C., C.L. Chang, C.S. Yu, P.Y. Chen and J.S. Yang et al., 2011. Induction of apoptosis by curcumin in murine myelomonocytic leukemia WEHI-3 cells is mediated via endoplasmic reticulum stress and mitochondria-dependent pathways. Environ. Toxicol., 28: 255-266.
    CrossRef  |  Direct Link  |  
  111. Chung, J.G., 2011. A novel synthetic 2-(3-methoxyphenyl)-6,7-methylenedioxoquinolin-4-one arrests the G2/M phase arrest via Cdc25c and induces apoptosis through caspase- and mitochondria-dependent pathways in TSGH8301 human bladder cancer cells. Int. J. Oncol., 40: 731-738.
    CrossRef  |  Direct Link  |  
  112. Chueh, F.S., Y.Y. Chen, A.C. Huang, H.C. Ho and C.L. Liao et al., 2011. Bufalin-inhibited migration and invasion in human osteosarcoma U-2 OS cells is carried out by suppression of the matrix metalloproteinase-2, ERK, and JNK signaling pathways. Environ. Toxicol., 29: 21-29.
    CrossRef  |  Direct Link  |  
  113. Chen, N.G., C.C. Lu, Y.H. Lin, W.C. Shen and C.H. Lai et al., 2011. Proteomic approaches to study epigallocatechin gallate-provoked apoptosis of TSGH-8301 human urinary bladder carcinoma cells: roles of AKT and heat shock protein 27-modulated intrinsic apoptotic pathways. Oncol. Rep., 26: 939-947.
    CrossRef  |  Direct Link  |  
  114. Lu, H.F., Y.J. Chie, M.S. Yang, K.W. Lu and J.J. Fu et al., 2010. Apigenin induces apoptosis in human lung cancer H460 cells through caspase- and mitochondria-dependent pathways. Hum. Exp. Toxicol., 30: 1053-1061.
    CrossRef  |  Direct Link  |  
  115. Lai, T.Y., J.J. Lin, W.W. Huang, S.C. Kuo and Y.F. Wen et al., 2010. Arsenic trioxide (As2O3) inhibits murine wehi-3 leukemia in BALB/c mice in vivo. Environ. Toxicol., 27: 364-371.
    CrossRef  |  Direct Link  |  
  116. Lai, K.C., S.C. Hsu, J.S. Yang, C.L. Kuo and S.W. Ip et al., 2010. 2-(3-Methoxyphenyl)-6,7-methylenedioxoquinolin-4-one, a novel synthetic compound, inhibited migration and invasion in TSGH8301 human bladder cancer cells. Hum. Exp. Toxicol., 10.1177/0960327110386257.
    CrossRef  |  PubMed  |  
  117. Ip, S.W., S.H. Lan, A.C. Huang, J.S. Yang and Y.Y. Chen et al., 2010. Capsaicin induces apoptosis in SCC-4 human tongue cancer cells through mitochondria-dependent and -independent pathways. Environ. Toxicol., 27: 332-341.
    CrossRef  |  Direct Link  |  
  118. Hsu, H.Y., J.S. Yang, K.W. Lu, C.S. Yu and S.T. Chou et al., 2010. An experimental study on the antileukemia effects of gypenosides in vitro and in vivo. Integr. Cancer Ther., 10: 101-112.
    CrossRef  |  Direct Link  |  
  119. Yu, F.S., C.C. Wu, C.T. Chen, S.P. Huang and J.S. Yang et al., 2009. Diallyl sulfide inhibits murine WEHI-3 leukemia cells in BALB/c mice in vitro and in vivo. Hum. Exp. Toxicol., 28: 785-790.
    CrossRef  |  Direct Link  |  
  120. Yang, J.S., G.W. Chen, T.C. Hsia, H.C. Ho and C.C. Ho et al., 2009. Diallyl disulfide induces apoptosis in human colon cancer cell line (COLO 205) through the induction of reactive oxygen species, endoplasmic reticulum stress, caspases casade and mitochondrial-dependent pathways. Food Chem. Toxicol., 47: 171-179.
    CrossRef  |  Direct Link  |  
  121. Tang, Y.J., J.S. Yang, C.F. Lin, W.C. Shyu and M. Tsuzuki et al., 2009. Houttuynia cordata thunb extract induces apoptosis through mitochondrial-dependent pathway in HT-29 human colon adenocarcinoma cells. Oncol. Rep., 22: 1051-1056.
    CrossRef  |  Direct Link  |  
  122. Lu, H.F., K.C. Lai, S.C. Hsu, H.J. Lin and C.L. Kuo et al., 2009. Involvement of matrix metalloproteinases on the inhibition of cells invasion and migration by emodin in human neuroblastoma SH-SY5Y cells. Neurochem. Res., 34: 1575-1583.
    CrossRef  |  Direct Link  |  
  123. Lin, J.P., J.S. Yang, C.C. Lu, J.H. Chiang and C.L. Wu et al., 2009. Rutin inhibits the proliferation of murine leukemia wehi-3 cells in vivo and promotes immune response in vivo. Leukemia Res., 33: 823-828.
    CrossRef  |  Direct Link  |  
  124. Lee, T.Y., Y.H. Kim, S.W. Yoon, J.C. Choi and J.M. Yang et al., 2009. Oral administration of poly-gamma-glutamate induces TLR4- and dendritic cell-dependent antitumor effect. Cancer Immunol., Immunother., 58: 1781-1794.
    CrossRef  |  Direct Link  |  
  125. Kuo, H.M., H.C. Tsai, Y.L. Lin, J.S. Yang and A.C. Huang et al., 2009. Mitochondrial-dependent caspase activation pathway is involved in baicalein-induced apoptosis in human hepatoma J5 cells. Int. J. Oncol., 35: 717-724.
    CrossRef  |  Direct Link  |  
  126. Ji, B.C., W.H. Hsu, J.S. Yang, T.C. Hsia and C.C. Lu et al., 2009. Gallic acid induces apoptosis via caspase-3 and mitochondrion-dependent pathways in vitro and suppresses lung xenograft tumor growth in vivo. J. Agric. Food Chem., 57: 7596-7604.
    CrossRef  |  Direct Link  |  
  127. Hsu, S.C., J.S. Yang, C.L. Kuo, C. Lo and J.P. Lin et al., 2009. Novel quinolone CHM-1 induces apoptosis and inhibits metastasis in a human osterogenic sarcoma cell line. J. Orthop. Res., 27: 1637-1644.
    CrossRef  |  Direct Link  |  
  128. Chou, L.C., J.S. Yang, L.J. Huang, H.C. Wu and C.C. Lu et al., 2009. The synthesized 2-(2-fluorophenyl)-6,7-methylenedioxyquinolin-4-one (CHM-1) promoted G2/M arrest through inhibition of CDK1 and induced apoptosis through the mitochondrial-dependent pathway in CT-26 murine colorectal adenocarcinoma cells. J. Gastroenterol., 44: 1055-1063.
    CrossRef  |  Direct Link  |  
  129. Chien, S.Y., Y.C. Wu, J.G. Chung, J.S. Yang and H.F. Lu et al., 2009. Quercetin-induced apoptosis acts through mitochondrial-and caspase-3- dependent pathways in human breast cancer MDA-MB-231 cells. Human Experimental Toxicology, 28: 493-503.
    CrossRef  |  
  130. Chen, T.C., K.C. Lai, J.S. Yang, C.L. Liao and T.C. Hsia et al., 2009. Involvement of reactive oxygen species and caspase-dependent pathway in berberine-induced cell cycle arrest and apoptosis in C6 rat glioma cells. Int. J. Oncol., 34: 1681-1690.
    CrossRef  |  
  131. Chen, J.C., K.W. Lu, M.L. Tsai, S.C. Hsu and C.L. Kuo et al., 2009. Gypenosides induced G0/G1 arrest via CHk2 and apoptosis through endoplasmic reticulum stress and mitochondria-dependent pathways in human tongue cancer SCC-4 cells. Oral Oncol., 45: 273-283.
    CrossRef  |  Direct Link  |  
  132. Chang, Y.H., J.S. Yang, J.L. Yang, C.L. Wu and S.J. Chang et al., 2009. Ganoderma lucidum extracts inhibited leukemia WEHI-3 cells in BALB/c mice and promoted an immune response in vivo. Biosci. Biotechnol. Biochemis., 73: 2589-2594.
    CrossRef  |  PubMed  |  Direct Link  |  
  133. Lin, S.S., H.P. Huang, J.S. Yang, J.Y. Wu and T.C. Hsai et al., 2008. DNA damage and endoplasmic reticulum stress mediated curcumin-induced cell cycle arrest and apoptosis in human lung carcinoma a-549 cells through the activation caspases cascade- and mitochondrial-dependent pathway. Cancer Lett., 272: 77-90.
    CrossRef  |  Direct Link  |  
  134. Hsieh, Y.S., Lee Y.L., S.F. Yang, J.S. Yang, N. Chen, S.C. Chen and C.M. Shih, 2007. Association of EcoRI polymorphism of the metastasis-suppressor Gene NME1 with susceptibility to and severity of non-small cell lung cancer. Lung cancer, 58: 191-195.
    CrossRef  |  Direct Link  |  
  135. Chou, L.C., L.J. Huang, J.S. Yang, F.Y. Lee, C.M. Teng and S.C. Kuo, 2007. Synthesis of furopyrazole analogs of 1-benzyl-3-(5-hydroxymethyl- 2-furyl) indazole (YC-1) as novel anti-leukemia agents. Bioorganic Med. Chem., 15: 1732-1740.
    CrossRef  |  
  136. Wu, C.C., J.P. Lin, J.S. Yang, S.T. Chou and S.C. Chen et al., 2006. Capsaicin induced cell cycle arrest and apoptosis in human esophagus epidermoid carcinoma ce 81T/VGH cells through the elevation of intracellular reactive oxygen species and Ca2+ productions and caspase-3 activation. Mutation Res./Fundam. Mol. Mech. Mutagen., 601: 71-82.
    CrossRef  |  Direct Link  |  
  137. Lin, H.L., J.S. Yang, J.H. Yang, S.S. Fan, W.C. Chang, Y.C. Li and J.G. Chung, 2006. The role of Ca2+ on the DADS-induced apoptosis in mouse-rat hybrid retina ganglion cells (N18). Neurochem. Res., 31: 383-393.
    CrossRef  |  Direct Link  |  
  138. Lin, C.F., J.S. Yang, C.Y. Chang, S.C. Kuo, M.R. Lee and L.J. Huang, 2005. Synthesis and anticancer activity of benzyloxybenzaldehyde derivatives against HL-60 cells. Bioorg. Medic. Chem., 13: 1537-1544.
    CrossRef  |  Direct Link  |  
  139. Huang, W.W., J.S. Yang, C.F. Lin, W.J. Ho and M.R. Lee, 2005. Pycnogenol induces differentiation and apoptosis in human promyeloid leukemia HL-60 cells. Leukemia Res., 29: 685-692.
    CrossRef  |  Direct Link  |