Dr. Suresh  Challa
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Dr. Suresh Challa

Scientist E and Deputy Director
National Institute of Nutrition, India


Highest Degree
Ph.D. in Biochemistry from S. V. University, India

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Biography

Dr. Suresh Challa has obtained his Master’s Degree in Biochemistry from Sri Venkateswara University, Tirupati in the year 1993 and received Gold Medal for being the first rank holder in the university. He has obtained his Ph.D in Biochemical Toxicology from the same university. His research interests includes Biochemistry, Cell Biology, Cancer Biology, Nutritional Biochemistry and Environmental Toxicology. His present research involves in addressing the pathologies associated with Osteoporosis and different therapeutic approaches in combating the disease and studying the intracellular effects of Cowpea isoflavones using both in vitro and in vivo models. Another area of research interest is being studying the synergic toxic effects of environmental Heavy metal Lead and amyloid peptides on brain using Human brain cell. Also making efforts in examining the toxic effects of these two in conditions such as Alzheimer’s and its protection by different neuroprotective compounds. He has experience in working with different areas such as Synthesis of Betulinic acid like derivatives and their anti-cancer effects, Photodynamic therapy and cancer prevention, phytoestrogens and their role in the adipocyte cell metabolism and also in the areas of colon cancer and obesity. He has been recognized as PhD research supervisor at Osmania university, Nagarjuna University, NTR Health University and JNTU, Hyderabad in the subjects of Biochemistry, Biotechnology and Nutrition. Dr. Suresh has received NIH Visiting Scientist Fellowship from 2004-2005 (one year) and also during 2010-2012 (two years) and did his research at USA. He also obtained prestigious ICMR Young Bio-medical Scientist fellowship for the years 2014-2015. He is a Fellow of Association of Biotechnology and Pharmacy (FABP) and an active member of several scientific bodies. He is serving as faculty at NIN for different courses and also as Board of studies member at various universities.

Area of Interest:

Pharmacology and Toxicology
100%
Environmental Toxicology
62%
Animal Sciences
90%
Biochemistry
75%
Cell Biology
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Suresh, C. and P.K. Dixit, 2016. Mitigative effects of koenidine in reducing the toxicity induced by heavy metal lead in human neuroblastoma cells. J. Chem. Biol. Ther., Vol. 1. .
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  2. Rishika, J., V. Vijayalakshmi, A. Rajanna, V. Naresh and C. Suresh, 2016. Possible synergistic role of Cowpea isoflavones and vitamin D combo in the bone formation of MG-63 osteoblasts. Vitamins Miner., .
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  3. Rao, S. and C. Suresh, 2015. Analysis of genetic differentiation of few edible Cassia species using RAPD molecular markers. Int. J. Pharm. Pharm. Res., 3: 58-65.
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  4. Jyothi, K.S.N., M. Shailaja, J. Viveni and C. Suresh, 2014. Identification of a proteinaceous alpha amylase inhibitor from a medicinal herb Oxalis corniculata L. (Oxalidaceae). J. Homeopathy Ayurvedic Med., 3: 165-168.
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  5. Rao, S. and C. Suresh, 2013. In vitro and In vivo Effects of the leaf extracts of cassia tora and cassia sophera in reducing the cytotoxicity and angiogenesis. Br. Biotechnol. J., 39: 377-389.
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  6. Jyothi, K.S.N., P. Hemalatha, A. Avanthi and S. Challa, 2013. A comparative analysis on the alpha amylase inhibitory potential of six ornamental medicinal plants. J. Nat. Prod. Plant Resour., 3: 1-6.
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  7. Suresh, C., J. Johnson, R. Mohan and C.S. Chetty, 2012. Synergistic effects of amyloid peptides and lead on human neuroblastoma cells. Mol. Biol. Lett., 17: 408-421.
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  8. Suresh, C., H. Zhao, A. Gumbs, C.S. Chetty and H.S. Bose, 2012. New ionic derivatives of betulinic acid as highly potent anti-cancer agents. Bioorg. Med. Chem. Lett., 22: 1734-1738.
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  9. Rao, S., T. Vijayadeepthi, M. Zoheb and C. Suresh, 2012. Evaluation of antioxidant and antimicrobial potential of two edible Cassia species to explore their Neutraceutical values. J. Pharm. Res., 5: 1650-1655.
  10. Zhao, H., S. Holmes, G.A. Baker, S. Challa, H.S. Bose and Z. Song, 2011. Ionic derivatives of betulinic acid as novel HIV-1 protease inhibitors. J. Enzyme Inhib. Med. Chem., 27: 715-721.
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  11. Suresh, C., J. Johnson, T.M. Modeste and C.S. Chetty, 2011. Protective role of epigallocatechin 3-gallate against lead-induced toxicity in human neuroblastoma cells. Toxicol. Environ. Chem., 93: 1018-1027.
  12. Pasumarthi, S., M.K. Chimata, C.S. Chetty and S. Challa, 2011. Screening of phytochemical compounds in selected medicinal plants of deccan plateau and their viability effects on Caco-2 Cells. J. Med. Plant Res., 5: 6955-6962.
  13. Jyothi, K.S.N., P. Hemalatha and S. Challa, 2011. Evaluation of alpha amylase inhibitory potential of three medicinally important traditional wild food plants of India. Int. J. Green Pharm., 5: 95-99.
  14. Jonnalagadda, P.R., A.Y.E. Prasad, K.A. Reddy, C. Suresh and M. Vishnu et al., 2010. Biochemical alterations of certain health parameters in cotton growing farmers exposed to organophosphorous and pyrethroid insecticides. African J. Biotechnol., 9: 8369-8377.
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  15. Chimata, M.K., S. Pasumarthi and S. Challa, 2010. Optimization and production of extracellular amylase from newly isolated Aspergillus species by Submerged Fermentation. Curr. Trends Biotechnol. Pharm., 4: 795-800.
  16. Chimata, M.K., P. Sasidhar and S. Challa, 2010. Production of extracellular amylase from agricultural residues by a newly isolated Aspergillus species in solid state fermentation. Afr. J. Biotechnol., 9: 5162-5169.
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  17. Chennaiah, S., V. Vijayalakshmi and C. Suresh, 2010. Effect of the supplementation of dietary rich phytoestrogens in altering the vitamin D levels in diet induced osteoporotic rat model. J. Steroid Biochem. Mol. Biolo., 121: 268-272.
  18. Nagajyoti, P.C., N. Dinakar, S. Suresh, Y. Udaykiran, C. Suresh, T.N.V.K.V. Prasad and T. Damodharam, 2009. Biomass industrial effluent effect on carbohydrates, aminoacids, nitrite and nitrite enzyme activities of Arachis hypogaea L. Agric. Sci. China, 8: 203-215.
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  19. Dinakar, N., P.C. Nagajyothi, S. Suresh, T. Damodharam and C. Suresh, 2009. Cadmium induced changes on proline, antioxidant enzymes, nitrate and nitrite reductases in Arachis hypogaea L. J. Environ. Biol., 30: 289-294.
    PubMed  |  Direct Link  |  
  20. Suresh, C., M.C. Vemuri and C.S. Chetty, 2008. Effect of epigallocatechin 3-gallate in human neuroblastoma cells exposed to lead. Comparative Biochem. Physiol. Part C: Toxicol. Pharmacol., 148: 462-463.
  21. Suresh, C., J. Padmaja, P.U. Kumar, K. Divya, P. Sandesh and P. Swadeep, 2008. Alterations in the antioxidant profile in patients with colorectal carcinoma. Curr. Trends Biotechnol. Pharm., 2: 531-537.
  22. Nagajyoti, P.C., N. Dinakar, T. Prasad, C. Suresh and T. Damodharam, 2008. Heavy metal toxicity: Industrial effluent effect on groundnut (Arachis hypogaea L.) seedlings. J. Applied Sci. Res., 4: 110-121.
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  23. Nagajyothi, P.C., N. Dinakar, Y. Udaykiran, K. Prasad, C. Suresh and T. Damodharam, 2008. Effect of biomass power plant effluent on biochemical parameters of Arachis hypogaea L. Asian J. Res. Chem., 20: 5489-5496.
  24. Nagajyothi, P.C., N. Dinakar, S. Suresh, Y. Udaykiran, C. Suresh and T. Damodharam, 2008. Effect of industrial effluent on the morphological parameters and chlorophyll content of green gram (Phaseolus aureus Roxb). J. Environ. Biol., 30: 385-388.
    PubMed  |  Direct Link  |  
  25. Chetty, C.S., M.C. Vemuri, G.R. Reddy and C. Suresh, 2007. Protective effect of 17-beta-estradiol in Human Neurocellular models of Lead exposure. NeuroToxicology, 28: 396-401.
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  26. Suresh, C., A.O. Dennis, J. Heinz, M.C. Vemuri and C.S. Chetty, 2006. Melatonin protection against lead induced changes in human neuroblastoma cell cultures. Int. J. Toxicol., 25: 459-464.
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  27. Prakash, M.S., S. Chennaiah, Y.S.R. Murthy, E. Anjaiah and C. Suresh, 2006. Altered adenosine deaminase activity in type-2 diabetes mellitus. J. Indian Acad. Clin. Med., 7: 114-117.
  28. Chetty, C.S., M.C. Vemuri, K. Campbell and C. Suresh, 2005. Lead-induced cell death of human neuroblastoma cells involves GSH deprivation. Cell. Mol. Biol. Lett., 10: 413-423.
    PubMed  |  Direct Link  |  
  29. Suresh, C. and R.S. Tiwary, 2000. Role of Nutrients in cancer (Review). J. App. Nutr., 25: 1-9.