Dr. Kulandaivelu Umasankar
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Dr. Kulandaivelu Umasankar

Head & Professor
KL Deemed to be University, India

Highest Degree
Ph.D. in Pharmaceutical Sciences from Jawaharlal Nehru Agricultural University, India

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Area of Interest:

Biomedical Sciences
100%
Developmental Biology
62%
Bioinformatics
90%
Biochemical Analysis
75%
Medicinal Chemistry
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Narender, M., K. Umasankar, J. Malathi, A.R. Reddy, K.R. Umadevi, A.V.N. Dusthackeer and K.V. Rao, 2016. Synthesis, in vitro antimycobacterial evaluation and docking studies of some new 5,6,7,8-tetrahydropyrido [4′,3′:4,5] thieno [2,3-d] pyrimidin-4 (3H)-one schiff bases. Bioorg. Med. Chem. Lett., 26: 836-840.
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  2. Eggadi, V., U. Kulandaivelu, S.B.B. Sheshagiri and V.R. Jupalli, 2016. Evaluation of antioxidant, antimicrobial and anticancer activity of thiazole tagged isatin hydrazones. J. Pharm. Chem., 3: 4-9.
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  3. Venkateshwarlu, E., B.S.S. Bhava, S.A. Bharadwaj, R.S. Kumar, K. Umasankar and J.V. Rao, 2015. Evaluation of diuretic and antidiabetic activity of esculin in wistar rats. Int. J. Pharm. Biol. Sci., 5: 267-276.
  4. Venkateshwarlu, E., B.S.S. Bhava, R.S. Kumar, R.J. Venkateshwar, E. Gouthami and K. Umasankar, 2015. Evaluation of diuretic activity of Syzygium cumini and its effect on prostaglandin system. Orient. Pharm. Exp. Med., 15: 45-51.
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  5. Kulandaivelu, U., S. Challuri, R.A. Reddy, G. Periyasamy and S. Boyapati, 2015. Synthesis, antiglycating and antioxidant activities of triazolo hexahydroquinazolines. J. Pharm. Chem., 2: 6-11.
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  6. Jupally, V.R., V. Eggadi, S.B.B. Sheshagiri and U. Kulandaivelu, 2015. Synthesis and evaluation of neuropharmacological profile of isatin-3-[N2-(2-benzalaminothiazol-4-yl)] hydrazones. Egypt. Pharm. J., 14: 130-138.
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  7. Eggadi, V., S.B.B. Sheshagiri, A. Devandla, N. Dasi and U. Kulundaivelu et al., 2015. Effect of atorvastatin on pharmacology of sitagliptin in streptozotocin-nicotinamide induced type-II diabetes in rats. Biol. Med., 7: 1-4.
  8. Eggadi, V., B.S.S. Bhava, P. Sriram and S.K. Revoori, 2015. Pharmacokinetic and pharmacodynamic interaction between simvastatin and diltiazem in rats with induced hypercholesterolaemia and hypertension. Formulation Dev. Anal., 1: 15-20.
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  9. Alavala, R.R., U. Kulandaivelu, P. Bonagiri, S. Boyapati, V. Jayaprakash and A.T. Subramaniam, 2015. Synthesis and antiviral activity of dihydropyrimidines-ciprofloxacin mannich bases against various viral strains. Anti-Infect. Agents, 13: 154-165.
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  10. Alavala, R.R., U. Kulandaivelu, P. Bonagiri, S. Boyapati, V. Jayaprakash and A.T. Subramaniam, 2015. Synthesis and antiviral activity of dihydropyrimidines-ciprofloxacin mannich bases against various vairal strains. Anti-Infect. Agents, 13: 154-165.
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  11. Umasankar, K., C. Bhawatha, B. Shireesha and A.R. Reddy, 2014. Synthesis antimicro-bial and anticancer activity of 1-[(arylalkylidene)amino]-3-(4H-1, 2, 4-triazol-4-yl) thiourea. J. Pharm. Chem., 1: 5-9.
  12. Patchimatla, A., S.R. Kankanala, S.S. Bandaru, U. Kulindaivelu, V.R. Jupally and V. Eggadi, 2014. Investigation of lipid profile and occular oxidative stress of Chloroxylon swietenia on streptozotocin‑nicotinamide‑induced diabetic rats. Int. J. Green Pharm., 8: 90-96.
  13. Pashikanti, G., U. Kulundaivelu, V.R. Jupalli, S.B.B. Sheshagiri and V. Eggadi, 2014. Anti-arthritic activity of ethanolic extract from the leaves of Commiphora caudate (Linn.) in complete Freund's adjuvant-induced arthritic rats. Niger. J. Exp. Clin. Biosci., 2: 42-48.
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  14. Kulandaivelu, U., L.M. Chilakamari, S.S. Jadav, T.R. Rao and K.N. Jayaveera et al., 2014. Hydroxamates of para-aminobenzoic acid as selective inhibitors of HDAC8. Bioorganic Chem., 57: 116-120.
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  15. Kulandaivelu, U., L.M. Chilakamari, S.S. Jadav, T.R. Rao and K.N. Jayaveera et al., 2014. Hydroxamates of para-aminobenzoic acid as selective inhibitors of HDAC8. Bioorg. Chem., 57: 116-120.
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  16. Kulandaivelu, U., B. Chawada, S. Boyapati and A.R. Reddy, 2014. Synthesis antimicrobial and anticancer activity of 1-[(arylalkylidene)amino]-3-(4H-1,2,4-triazol-4-yl) thiourea. J. Pharm. Chem., 1: 5-9.
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  17. Eggadi, V., S. Gundamedi, S.B.B. Sheshagiri, S.K. Revoori, V.R. Jupally and U. Kulandaivelu, 2014. Evaluation of anticancer activity of Annona muricata in 1,2-dimethyl hydrazine induced colon cancer. World Applied Sci. J., 32: 444-450.
  18. Venkateshwarlu, E., B.S.S. Bhava, K. Umasankar and J.V. Rao, 2013. Evaluation of diuretic activity of isatin derivatives in wistar rats. J. Pharm. Nutr. Sci., 3: 141-148.
  19. Subrahmanyam, B.S., B.S.S. Bhava, E. Venkateshwarlu, K. Umasankar, P. Dileep and S.V. Murthy, 2013. Efficacy of oral anti-diabetic agents for glycemic control intype-2 diabetic patients with obesity. Global J. Pharmacol., 7: 311-315.
  20. Reddy, A.R., P. Dinesh, A.S. Prabhakar, K. Umasankar, B. Shireesha and M.B. Raju, 2013. A comprehensive review on sar of curcumin. Mini Rev. Med. Chem., 13: 1769-1777.
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  21. Mahapatra, M., U. Kulandaivelu, P. Saiko, G. Graser and T. Szekeres et al., 2013. Methyl-2-arylidene hydrazinecarbodithioates: Synthesis and biological activity. Chem. Papers, 67: 650-656.
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  22. Mahapatra, M., U. Kulandaivelu, P. Saiko, G. Graser and T. Szekeres et al., 2013. Methyl-2-arylidene hydrazinecarbodithioates: Synthesis and biological activity. Chem. Papers, 67: 650-656.
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  23. Kulandaivelu, U., B. Shireesha, C. Mahesh, J.V. Vidyasagar and T.R. Rao et al., 2013. Synthesis antimicrobial and anticancer activity of N′-arylmethylidene-piperazine-1-carbothiohydrazide. Med. Chem. Res., 22: 2802-2808.
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  24. Kulandaivelu, U., B. Shireesha, C. Mahesh, J.V. Vidyasagar and T.R. Rao et al., 2013. Synthesis antimicrobial and anticancer activity of N′-arylmethylidene-piperazine-1-carbothiohydrazide. Med. Chem. Res., 22: 2802-2808.
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  25. Eggadi, V., U. Kulandaivelu, B.S. Sharvanabhava and V.R. Jupally, 2013. Screening of the anticonvulsant activity of some isatin derivatives in experimental seizure models and its effect on brain GABA levels in mice. Am. J. Pharmacol. Sci., 1: 42-46.
  26. Venkateshwarlu, E., J.V. Rao, K. Umasankar and G. Dheeraj, 2012. Study of anti-inflammatory, analgesic and antipyretic activity of novel isatin derivatives. Asian J. Pharm. Clin. Res., 5: 187-190.
  27. Venkateshwarlu, E., J.V. Rao, K. Umasankar and G. Dheeraj, 2012. Study of anti-inflammatory, analgesic and antipyretic activity of novel isatin derivatives. Asian J. Pharm. Clin. Res., 5: 187-190.
  28. Prabahar, S.A., A.R. Reddy, K. Umasankar, B. Shireesah and I. Kundan, 2012. Two dimensional quantitative structure activity relationship (2d-QSAR) studies of Tacrine analogs for Acetyl choline esterase (AChE inhibition) using Multiple linier multiple linear regression analysis. Lett. Drug Design Discovery, 9: 858-866.
  29. Pore, D., R. Alli, A.S.C. Prabhakar, R.R. Alavala, U. Kulandaivelu and S. Boyapati, 2012. Solid-phase microwave assisted synthesis of curcumin analogs. Lett. Organic Chem., 9: 447-450.
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  30. Pore, D., R. Alli, A.S.C. Prabhakar, R.R. Alavala, U. Kulandaivelu and S. Boyapati, 2012. Solid-phase microwave assisted synthesis of curcumin analogs. Lett. Org. Chem., 9: 447-450.
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  31. Mahendar, P., K. Sirisha, U. Kulandaivelu, P.L.J. Shankar, T. Radhika and A. Sadanandam, 2012. In silico evaluation of TERT inhibition by anticancer drugs. J. Mol. Model., 18: 4739-4744.
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  32. Achanta, P.S., R.R. Alavala, U. Kulandaivelu, S. Boyapati and K. Ingale, 2012. 2D-QSAR studies of tacrine analogues for acetylcholine esterase (AChE) inhibition using multiple linear regression analysis. Lett. Drug Des. Discov., 9: 858-866.
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  33. Srujana, M., B. Jyothi, C. Mahesh, M.S. Reddy, K. Umasankar and V.M. Reddy, 2011. Synthesis and pharmacological evaluation of novel mannich bases of quinazolines. Scient. J. Pharm., 1: 30-37.
  34. Sirisha, K., M.C. Shekhar, K. Umasankar, P. Mahendar, A. Sadanandam, G. Achaiah and V.M. Reddy, 2011. Molecular docking studies and in vitro screening of new dihydropyridine derivatives as human MRP1 inhibitors. Bioorg. Med. Chem., 19: 3249-3254.
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  35. Kulandaivelu, U., V.G. Padmini, K. Suneetha, B. Shireesha and J.V. Vidyasagar et al., 2011. Synthesis, antimicrobial and anticancer activity of new thiosemicarbazone derivatives. Arch. Pharm., 344: 84-90.
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  36. Thangadurai, S.A., M. Maninder, W. Sharad, A. Shyam, K. Umasankar and B. Narasimhan, 2010. Biological values of the heterocyclic compounds quinazoline. Acta Pharm. Sci., 53: 347-361.
  37. Suresh, V., V.M. Kumar, A. Suresh, N.S. Kumar, G. Arunachalam and K. Umasankar, 2010. CNS activity of ethanol extract of Wedelia chinensis in experimental animals. Int. J. Pharm. Sci. Nanotechnol., 3: 881-886.
  38. Shireesha, B., K. Umasankar, S. Srinivas and V.M. Reddy, 2010. Synthesis, antimicrobial evaluation and docking studies of novel 4-quinazolinyl heterocyclics as DNA-gyrase inhibitors. Arch. Der Pharm., 10: 570-576.
  39. Karuppasamy, M., M. Mahapatra, S. Yabanoglu, G. Ucar and B.N. Sinha et al., 2010. Development of selective and reversible pyrazoline based MAO-A inhibitors: Synthesis, biological evaluation and docking studies. Bioorganic Med. Chem., 18: 1875-1881.
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  40. Karuppasamy, M., M. Mahapatra, S. Yabanoglu, G. Ucar and B.N. Sinha et al., 2010. Development of selective and reversible pyrazoline based MAO-A inhibitors: Synthesis, biological evaluation and docking studies. Bioorg. Med. Chem., 18: 1875-1881.
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  41. Boyapati, S., U. Kulandaivelu, S. Sangu and M.R. Vanga, 2010. Synthesis, antimicrobial evaluation and docking studies of novel 4‐substituted quinazoline derivatives as DNA‐gyrase inhibitors. Arch. Pharm., 343: 570-576.
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  42. Babu, G.S., T. Swathy, P.S. Malathy, B. Srinivas, K. Umasankar, J.V. Rao and N. Raghunandan, 2010. Synthesis, characterization and evaluation of novel substituted benzo-indolylidene acetohydrazide derivatives as anti-microbial agents. Pharm. Lett., 2: 408-415.
  43. Babu, G.S., N. Rajani, P.S. Malathy, B. Srinivas, U. Kulandaivelu and J.V. Rao, 2010. Synthesis, characterization and evaluation of novel N-(1H-benzimidazol-2-yl)-2-isatinylidene-hydrazinecarboxamide derivatives as anti-inflammatory agents. Der Pharm. Chem., 2: 196-204.
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  44. Lalitha, K.G., T. Venkatachalam, R. Srinivasan, P. Kalaiselvi and K. Umasankar, 2009. A new analytical method development and validation for the simultaneous estimation of ramipril, atorvastatin and clopidogrel in capsule dosage form by RP-HPLC. J. Pharm. Chem., 3: 103-108.
  45. Shireesha, B., K.U. Shankar, A.R. Rao, K. Rajan and M. Raghuprasad, 2008. Design, synthesis and H1-antihistaminic activity of novel thieno [2,3-d] pyrimidinones. Int. J. Pharm. Sci. Nanotechnol., 1: 136-143.
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  46. Shireesha, B., K. Umasankar, A.R. Rao, K.S. Rajan and M. Raghuprasad, 2008. Design, synthesis and H1-antagonistic activity of novel thieno[2,3-d] pyrimidinones. Int. J. Pharm. Sci. Nanotechnol., 1: 136-143.