Dr. Khawaja Husnain Haider
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Dr. Khawaja Husnain Haider

Associate Professor
Sulaiman Al Rajhi College, Saudi Arabia

Highest Degree
PostDoc Fellow in Non Viral Vector Gene Delivery from Seoul National University, Korea

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Biography

Dr. Khawaja Husnain Haider obtained his PhD from University of Strathclyde, Glasgow, UK. Currently he is working as Associate Professor and teaching undergraduate Medical Students using Problem Based Learning approach, SRC at Kingdom of Saudi Arabia. Previously he was appointed as Research Scientist, Associate Professor, Assistant Professor at University of Cincinnati Medical Center, Cincinnati, Ohio, USA, Research Scientist at National University Medical Institutes, National University of Singapore, Singapore, and Associate Professor at University of the Punjab, Lahore-Pakistan. Dr. Khawaja received honors includes Gold Medal for standing first in the order of merit in the University during post-graduate M. Pharmacy studies, Charles Wallace Trust Merit Scholarship (UK), and KOSEF Merit Award (South Korea) for post-doctoral Fellowship. He has supervised 13 masters students thesis. He is also serving as reviewer for number of refereed journals. He also completed 12 research projects as principal investigator and co-investigator. He has published 125 research articles in journals, 9 book chapters, and 84 abstracts contributed as author/co-author.

Area of Interest:

Molecular Sciences
100%
Gene Therapy
62%
Stem Cell Therapy
90%
DNA as Drugs
75%
Regenerative Medicine
55%

Research Publications in Numbers

Books
0
Chapters
0
Articles
0
Abstracts
0

Selected Publications

  1. Ibrahim, A.Y., Q. Mehdi, A.O. Abbas, A. Alashkar and H.H. Khawaja, 2016. Induced pluripotent stem Cells: Next generation cells for tissue regeneration. J. Biomed. Sci. Eng,, 9: 226-244.
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  2. Al Goblan, A.S., B. Osman and H.H. Khawaja, 2016. Prediction of diabetic foot ulcer healing in type-2 diabetic subjects using routine clinical and laboratory parameters. Res. Rep. Endocr. Disord., 6: 11-16.
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  3. Lu, G., S. Jiang, M. Ashraf and K.H. Haider, 2012. Subcellular preconditioning of stem cells: Mito-Cx43 gene targeting is cytoprotective via shift of mitochondrial Bak and Bcl-xL balance. Regener. Med., 7: 323-334.
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  4. Lu, G., M. Ashraf and K.H. Haider, 2012. Insulin-like growth factor-1 preconditioning accentuates intrinsic survival mechanism in stem cells to resist ischemic injury by orchestrating protein kinase Cα-Erk1/2 activation. Antioxid. Redox Signal., 16: 217-227.
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  5. Li, L., H.K. Haider, L. Wang, G. Lu and M. Ashraf, 2012. Adenoviral short hairpin RNA therapy targeting phosphodiesterase 5a relieves cardiac remodeling and dysfunction following myocardial infarction. Am. J. Physiol.-Heart Circ. Physiol., 302: H2112-H2121.
    CrossRef  |  PubMed  |  Direct Link  |  
  6. Law, P.K., L. Ye, H.K. Haider, P. Li, D.M. Law and E.K.W. Sim, 2012. Therapeutic angiomyogenesis using human non-viral transduced VEGF165-myoblasts. Open J. Regener. Med., 1: 1-9.
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  7. Lai, V.K., M.R. Afzal, M. Ashraf, S. Jiang and H.K. Haider, 2012. Non-hypoxic stabilization of HIF-Iα during coordinated interaction between Akt and angiopoietin-1 enhances endothelial commitment of bone marrow stem cells. J. Mol. Med., 90: 719-730.
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  8. Lai, V.K., M. Ashraf, S. Jiang and K. Haider, 2012. MicroRNA-143 is a critical regulator of cell cycle activity in stem cells with co-overexpression of Akt and angiopoietin-1 via transcriptional regulation of Erk5/cyclin D1 signaling. Cell Cycle, 11: 767-777.
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  9. Konoplyannikov, M., K.H. Haider, V.K. Lai, R.P. Ahmed, S. Jiang and M. Ashraf, 2012. Activation of diverse signaling pathways by ex-vivo delivery of multiple cytokines for myocardial repair. Stem Cells Dev., 22: 204-215.
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  10. Kim, H.W., S. Jiang, M. Ashraf and K.H. Haider, 2012. Stem cell-based delivery of Hypoxamir-210 to the infarcted heart: Implications on stem cell survival and preservation of infarcted heart function. J. Mol. Med., 90: 997-1010.
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  11. Kim, H.W., F. Mallick, S. Durrani, M. Ashraf, S. Jiang and K.H. Haider, 2012. Concomitant activation of miR-107/PDCD10 and hypoxamir-210/Casp8ap2 and their role in cytoprotection during ischemic preconditioning of stem cells. Antioxid. Redox Signal., 17: 1053-1065.
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  12. Idris, N.M., M. Ashraf, R.P.H. Ahmed, J. Shujia and K.H. Haider, 2012. Activation of IL-11/STAT3 pathway in preconditioned human skeletal myoblasts blocks apoptotic cascade under oxidant stress. Regener. Med., 7: 47-57.
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  13. Haider, K.H. and M. Ashraf, 2012. Preconditioning approach in stem cell therapy for the treatment of infarcted heart. Progr. Mol. Biol. Transl. Sci., 111: 323-356.
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  14. Buccini, S., K.H. Haider, R.P. Ahmed, S. Jiang and M. Ashraf, 2012. Cardiac progenitors derived from reprogrammed mesenchymal stem cells contribute to angiomyogenic repair of the infarcted heart. Basic Res. Cardiol., Vol. 107. 10.1007/s00395-012-0301-5.
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  15. Ye, L., W. Zhang, L.P. Su, H.K. Haider and K.K. Poh et al., 2011. Nanoparticle based delivery of hypoxia-regulated VEGF transgene system combined with myoblast engraftment for myocardial repair. Biomaterials, 32: 2424-2431.
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  16. Takamiya, M., K.H. Haider and M. Ashraf, 2011. Identification and characterization of a novel multipotent sub-population of Sca-1+ cardiac progenitor cells for myocardial regeneration. PLoS ONE, Vol. 6. 10.1371/journal.pone.0025265.
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  17. Pasha, Z., H.K. Haider and M. Ashraf, 2011. Efficient non-viral reprogramming of myoblasts to stemness with a single small molecule to generate cardiac progenitor cells. PLoS ONE, Vol. 6. 10.1371/journal.pone.0023667.
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  18. Igura, K., H.K. Haider, R.P. Ahmed, S. Sheriff and M. Ashraf, 2011. Neuropeptide Y and neuropeptide Y Y5 receptor interaction restores impaired growth potential of aging bone marrow stromal cells. Rejuvenation Res., 14: 393-403.
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  19. Haider, H.K., A. Mustafa, Y. Feng and M. Ashraf, 2011. Genetic modification of stem cells for improved therapy of the infarcted myocardium. Mol. Pharmaceut., 8: 1446-1457.
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  20. Elmadbouh, I., H.K. Haider, M. Ashraf and J.C. Chachques, 2011. Preconditioning of human skeletal myoblast with stromal cell-derived factor-1α promotes cytoprotective effects against oxidative and anoxic stress. Int. J. Stem Cells, 4: 50-60.
    PubMed  |  Direct Link  |  
  21. Durrani, S., K.H. Haider, R.P. Ahmed, S. Jiang and M. Ashraf, 2011. Cytoprotective and proangiogenic activity of ex-vivo netrin-1 transgene overexpression protects the heart against ischemia/reperfusion injury. Stem Cells Dev., 21: 1769-1778.
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  22. Ahmed, R.P., M. Ashraf, S. Buccini, J. Shujia and H.K. Haider, 2011. Cardiac tumorgenic potential of induced pluripotent stem cells in an immunocompetent host with myocardial infarction. Regener. Med., 6: 171-178.
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  23. Ahmed, R.P., H.K. Haider, S. Buccini, L. Li, S. Jiang and M. Ashraf, 2011. Reprogramming of skeletal myoblasts for induction of pluripotency for tumor-free cardiomyogenesis in the infarcted heart. Circ. Res., 109: 60-70.
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  24. Ye, L., H.K. Haider, W.B. Esa, L. Su and P.K. Law et al., 2010. Liposome-based vascular endothelial growth factor-165 transfection with skeletal myoblast for treatment of ischaemic limb disease. J. Cell. Mol. Med., 14: 323-336.
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  25. Suzuki, Y., H.W. Kim, M. Ashraf and H.K. Haider, 2010. Diazoxide potentiates mesenchymal stem cell survival via NF-κB-dependent miR-146a expression by targeting Fas. Am. J. Physiol.-Heart Circ. Physiol., 299: H1077-H1082.
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  26. Sim, E.K.W., H.K. Haider, N. Lila, O. Schussler, J.C. Chachques and L. Ye, 2010. Genesis of myocardial repair with cardiac progenitor cells and tissue engineering. Heart Asia, 2: 109-111.
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  27. Sheriff, S., M. Ali, A. Yahya, K.H. Haider, A. Balasubramaniam and H. Amlal, 2010. Neuropeptide Y Y5 receptor promotes cell growth through extracellular signal-regulated kinase signaling and cyclic AMP inhibition in a human breast cancer cell line. Mol. Cancer Res., 8: 604-614.
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  28. Rufaihah, A.J., H.K. Haider, B.C. Heng, L. Ye and R.S. Tan et al., 2010. Therapeutic angiogenesis by transplantation of human embryonic stem cell-derived CD133+ endothelial progenitor cells for cardiac repair. Regener. Med., 5: 231-244.
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  29. Lu, G., H.K. Haider, A. Porollo and M. Ashraf, 2010. Mitochondria-specific transgenic overexpression of connexin-43 simulates preconditioning-induced cytoprotection of stem cells. Cardiovasc. Res., 88: 277-286.
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  30. Haider, K.H., S. Buccini, R.P. Ahmed and M. Ashraf, 2010. De novo myocardial regeneration: Advances and pitfalls. Antioxid. Redox Signal., 13: 1867-1877.
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  31. Haider, K.H., N.M. Idris, H.W. Kim, R.P. Ahmed, J. Shujia and M. Ashraf, 2010. MicroRNA-21 is a key determinant in IL-11/Stat3 anti-apoptotic signalling pathway in preconditioning of skeletal myoblasts. Cardiovasc. Res., 88: 168-178.
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  32. Haider, H.K., Y.J. Lee, S. Jiang, R.P. Ahmed, M. Ryon and M. Ashraf, 2010. Phosphodiesterase inhibition with tadalafil provides longer and sustained protection of stem cells. Am. J. Physiol.-Heart Circ. Physiol., 299: H1395-H1404.
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  33. Haider, H.K. and M. Ashraf, 2010. Preconditioning and stem cell survival. J. Cardiovasc. Transl. Res., 3: 89-102.
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  34. Durrani, S., M. Konoplyannikov, M. Ashraf and K.H. Haider, 2010. Skeletal myoblasts for cardiac repair. Regener. Med., 5: 919-932.
    CrossRef  |  Direct Link  |  
  35. Ahmed, R.P., K.H. Haider, J. Shujia, M.R. Afzal and M. Ashraf, 2010. Sonic Hedgehog gene delivery to the rodent heart promotes angiogenesis via iNOS/netrin-1/PKC pathway. PLoS ONE, Vol. 5. 10.1371/journal.pone.0008576.
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  36. Afzal, M.R., H.K. Haider, N.M. Idris, S. Jiang, R.P. Ahmed and M. Ashraf, 2010. Preconditioning promotes survival and angiomyogenic potential of mesenchymal stem cells in the infarcted heart via NF-κB signaling. Antioxid. Redox Signal., 12: 693-702.
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  37. Ye, L., K.O. Lee, L.P. Su, W.C. Toh and H.K. Haider et al., 2009. Skeletal myoblast transplantation for attenuation of hyperglycaemia, hyperinsulinaemia and glucose intolerance in a mouse model of type 2 diabetes mellitus. Diabetologia, 52: 1925-1934.
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  38. Lu, G., H.K. Haider, S. Jiang and M. Ashraf, 2009. Sca-1+ stem cell survival and engraftment in the infarcted heart dual role for preconditioning-induced connexin-43. Circulation, 119: 2587-2596.
    CrossRef  |  PubMed  |  Direct Link  |  
  39. Kim, H.W., H.K. Haider, S. Jiang and M. Ashraf, 2009. Ischemic preconditioning augments survival of stem cells via miR-210 expression by targeting caspase-8-associated protein 2. J. Biol. Chem., 284: 33161-33168.
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  40. Haider, K.H., H.W. Kim and M. Ashraf, 2009. Hypoxia-inducible factor-1α in stem cell preconditioning: Mechanistic role of hypoxia-related micro-RNAs. J. Thoracic Cardiovasc. Surg., 138: 257-257.
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  41. Haider, H.K., S.A. Akbar and M. Ashraf, 2009. Angiomyogenesis for myocardial repair. Antioxid. Redox Signal., 11: 1929-1944.
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  42. Ye, L., H.K. Haider, R. Tan, L. Su, P.K. Law, W. Zhang and E.K. Sim, 2008. Angiomyogenesis using liposome based vascular endothelial growth factor-165 transfection with skeletal myoblast for cardiac repair. Biomaterials, 29: 2125-2137.
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  43. Shujia, J., H.K. Haider, N.M. Idris, G. Lu and M. Ashraf, 2008. Stable therapeutic effects of mesenchymal stem cell-based multiple gene delivery for cardiac repair. Cardiovasc. Res., 77: 525-533.
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  44. Jiang, S., H.K. Haider, R.P. Ahmed, N.M. Idris, A. Salim and M. Ashraf, 2008. Transcriptional profiling of young and old mesenchymal stem cells in response to oxygen deprivation and reparability of the infarcted myocardium. J. Mol. Cell. Cardiol., 44: 582-596.
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  45. Haider, K.H., I. Elmadbouh, M. Jean-Baptiste and M. Ashraf, 2008. Nonviral vector gene modification of stem cells for myocardial repair. Mol. Med., 14: 79-86.
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  46. Haider, H.K., Y. Lei and M. Ashraf, 2008. MyoCell, a cell-based, autologous skeletal myoblast therapy for the treatment of cardiovascular diseases. Curr. Opin. Mol. Therapeut., 10: 611-621.
    PubMed  |  
  47. Haider, H.K., S. Jiang, N.M. Idris and M. Ashraf, 2008. IGF-1-overexpressing mesenchymal stem cells accelerate bone marrow stem cell mobilization via paracrine activation of SDF-1α/CXCR4 signaling to promote myocardial repair. Circ. Res., 103: 1300-1308.
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  48. Haider, H.K. and M. Ashraf, 2008. Strategies to promote donor cell survival: Combining preconditioning approach with stem cell transplantation. J. Mol. Cell. Cardiol., 45: 554-566.
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  49. Dai, Y., M. Ashraf, S. Zuo, R. Uemura and Y.S. Dai et al., 2008. Mobilized bone marrow progenitor cells serve as donors of cytoprotective genes for cardiac repair. J. Mol. Cell. Cardiol., 44: 607-617.
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  50. Ye, L., K.H. Haider, S. Jiang, R.S. Tan, W.C. Toh, R.W. Ge and E.K.W. Sim, 2007. Angiopoietin-1 for myocardial angiogenesis: A comparison between delivery strategies. Eur. J. Heart Failure, 9: 458-465.
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  51. Ye, L., K.H. Haider, C. Guo and E.K.W. Sim, 2007. Cell-based VEGF delivery prevents donor cell apoptosis after transplantation. Ann. Thoracic Surg., 83: 1233-1234.
    CrossRef  |  PubMed  |  Direct Link  |  
  52. Ye, L., H.K. Haider, W.B. Esa, P.K. Law and W. Zhang et al., 2007. Nonviral vector-based gene transfection of primary human skeletal myoblasts. Exp. Biol. Med., 232: 1477-1487.
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  53. Ye, L., H.K. Haider, S. Jiang, R.S. Tan, R. Ge, P.K. Law and E.K. Sim, 2007. Improved angiogenic response in pig heart following ischaemic injury using human skeletal myoblast simultaneously expressing VEGF165 and angiopoietin-1. Eur. J. Heart Failure, 9: 15-22.
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  54. Sim, E.K., L. Ye and H.K. Haider, 2007. New strategy for cardiac repair: Genetically modified skeletal myoblasts. Asian Cardiovasc. Thoracic Ann., 15: 183-184.
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  55. Rufaihah, A.J., H.K. Haider, B.C. Heng, L. Ye and W.S. Toh et al., 2007. Directing endothelial differentiation of human embryonic stem cells via transduction with an adenoviral vector expressing the VEGF165 gene. J. Gene Med., 9: 452-461.
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  56. Niagara, M.I., H.K. Haider, S. Jiang and M. Ashraf, 2007. Pharmacologically preconditioned skeletal myoblasts are resistant to oxidative stress and promote angiomyogenesis via release of paracrine factors in the infarcted heart. Circ. Res., 100: 545-555.
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  57. Lei, Y., K.H. Haider, R. Tan, W. Toh and P.K. Law et al., 2007. Transplantation of nanoparticle transfected skeletal myoblasts overexpressing vascular endothelial growth factor-165 for cardiac repair. Circulation, 116: 113-120.
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  58. Haider, K.H. and M. Ashraf, 2007. Developing super cells by modification with super anti-apoptotic factor. J. Mol. Cell. Cardiol., 42: 478-480.
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  59. Haider, H.K., L. Ye and M. Ashraf, 2007. Skeletal muscle derived stem cells for myocardial repair. Recent Patents Cardiovasc. Drug Discovery, 2: 205-213.
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  60. Guo, C., H.K. Haider, W.S. Shim, R.S. Tan and L. Ye et al., 2007. Myoblast-based cardiac repair: Xenomyoblast versus allomyoblast transplantation. J. Thoracic Cardiovasc. Surg., 134: 1332-1339.
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  61. Elmadbouh, I., H.K. Haider, S. Jiang, N.M. Idris, G. Lu and M. Ashraf, 2007. Ex vivo delivered stromal cell-derived factor-1α promotes stem cell homing and induces angiomyogenesis in the infarcted myocardium. J. Mol. Cell. Cardiol., 42: 792-803.
    CrossRef  |  Direct Link  |  
  62. Ye, L., K.H. Haider, J. Shujia, R. Tan and I.C. Song et al., 2006. Skeletal myoblast based delivery of angiogenic growth factors: A comparison between angiopoietin-1 and VEGF gene delivery for therapeutic angiogenesis in the heart. J. Geriatric Cardiol., 3: 152-160.
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  63. Ye, L., H.K. Haider and E.K.W. Sim, 2006. Adult stem cells for cardiac repair: A choice between skeletal myoblasts and bone marrow stem cells. Exp. Biol. Med., 231: 8-19.
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  64. Wang, Y., H.K. Haider, N. Ahmad, M. Xu, R. Ge and M. Ashraf, 2006. Combining pharmacological mobilization with intramyocardial delivery of bone marrow cells over-expressing VEGF is more effective for cardiac repair. J. Mol. Cell. Cardiol., 40: 736-745.
    CrossRef  |  PubMed  |  Direct Link  |  
  65. Wang, Y., H.K. Haider, N. Ahmad, D. Zhang and M. Ashraf, 2006. Evidence for ischemia induced host-derived bone marrow cell mobilization into cardiac allografts. J. Mol. Cell. Cardiol., 41: 478-487.
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  66. Rufaihah, A.J., H.K. Haider, K.M. Sim, P.Z. Ding, L.B. Ramos, S. Jiang and E.K. Sim, 2006. Cardioprotective effect of des-Aspartate-angiotensin-I (DAA-I) on cytokine gene expression profile in ligation model of myocardial infarction. Life Sci., 78: 1341-1351.
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  67. Law, P.K., D.M. Law, P. Lu, E.K.W. Sim and K.H. Haider et al., 2006. Human myoblast genome therapy. J. Geriatric Cardiol., 3: 135-151.
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  68. Jiang, S., H.K. Haider, N.M. Idris, A. Salim and M. Ashraf, 2006. Supportive interaction between cell survival signaling and angiocompetent factors enhances donor cell survival and promotes angiomyogenesis for cardiac repair. Circ. Res., 99: 776-784.
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  69. Haider, K.H., 2006. Bone marrow cells for cardiac regeneration and repair: Current status and issues. Expert Rev. Cardiovasc. Ther., 4: 557-568.
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  70. Ahmad, N., Y. Wang, K.H. Haider, B. Wang, Z. Pasha, O. Uzun and M. Ashraf, 2006. Cardiac protection by mitoKATP channels is dependent on Akt translocation from cytosol to mitochondria during late preconditioning. Am. J. Physiol.-Heart Circ. Physiol., 290: H2402-H2408.
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  71. Ye, L., H.K. Haider, S. Jiang, R. Ge, P.K. Law and E.K. Sim, 2005. In vitro functional assessment of human skeletal myoblasts after transduction with adenoviral bicistronic vector carrying human VEGF165 and angiopoietin-1. J. Heart Lung Transplant., 24: 1393-1402.
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  72. Ye, L., H.K. Haider, S. Jiang, L.H. Ling, R. Ge, P.K. Law and E.K.W. Sim, 2005. Reversal of myocardial injury using genetically modulated human skeletal myoblasts in a rodent cryoinjured heart model. Eur. J. Heart Failure, 7: 945-952.
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  73. Wang, Y., H.K. Haider, N. Ahmad and M. Ashraf, 2005. Mechanisms by which K ATP channel openers produce acute and delayed cardioprotection. Vascular Pharmacol., 42: 253-264.
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  74. Sim, E.K.W., K.H. Haider, S. Aziz, O.C. Ooi and P.K. Law, 2005. Myoblast transplantation on the beating heart. Int. Surg., 90: 148-150.
    PubMed  |  Direct Link  |  
  75. Lei, Y., K.H. Haider and E.K.W. Sim, 2005. Human skeletal myoblast for cardiac repair. Chin. Med. Res. J., 5: 1110-1115.
  76. Heng, B.C., T. Cao, H.K. Haider, A.J. Rufaihah and E.K.W. Sim, 2005. Utilizing stem cells for myocardial repair-to differentiate or not to differentiate prior to transplantation? Scandinavian Cardiovascular J., 39: 131-134.
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  77. Heng, B.C., I. McNiece, H.K. Haider, R.Y. Calne and T. Cao, 2005. Possible advantages of stem cell transfusion into the peripheral circulation, as opposed to localized transplantation in situ. Stem Cells Dev., 14: 351-353.
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  78. Heng, B.C., H.K. Haider, E.K.W. Sim, T. Cao, G.Q. Tong and S.C. Ng, 2005. Reprogramming autologous skeletal myoblasts to express cardiomyogenic function. Challenges and possible approaches. Int. J. Cardiol., 100: 355-362.
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  79. Heng, B.C., H.K. Haider, E.K. Sim, T. Cao, G.Q. Tong and S.C. Ng, 2005. Comments about possible use of human embryonic stem cell-derived cardiomyocytes to direct autologous adult stem cells into the cardiomyogenic lineage. Acta Cardiol., 60: 7-12.
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  80. Heng, B.C., H.K. Haider and T. Cao, 2005. Combining transfusion of stem/progenitor cells into the peripheral circulation with localized transplantation in situ at the site of tissue/organ damage: A possible strategy to optimize the efficacy of stem cell transplantation therapy. Med. Hypotheses, 65: 494-497.
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  81. Haider, K.H., Y. Lei, E.K.W. Sim and M. Ashraf, 2005. Cell based ex-vivo delivery of angiogenic growth factors for cardiac repair. Arterioscler Thromb Vasc Biol., Vol. 25. 10.1161/01.ATV.0000190665.72652.d7.
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  82. Haider, K.H. and M. Ashraf, 2005. Pre-differentiation of stem cells for transplantation: To be or not to be that is the question. ASIAO J., 51: 301-302.
  83. Haider, K.H. and M. Ashraf, 2005. Implantation of genetically manipulated bone marrow cells for cardiac repair. Cytotherapy, 7: 74-75.
  84. Haider, H.K., U. Royta and M. Ashraf, 2005. Role of pharmacologically mobilized endogenous bone marrow stem cells for cardiac repair. J. Heart Lung Trans., 24: 1996-1997.
  85. Haider, H.K. and M. Ashraf, 2005. Bone marrow stem cells in the infarcted heart. Coronary Artery Dis., 16: 99-103.
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  86. Haider, H.K. and M. Ashraf, 2005. Bone marrow stem cell transplantation for cardiac repair. Am. J. Physiol. Heart Circ. Physiol., 288: H2557-H2567.
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  87. Haider, H.K. and M. Ashraf, 2005. Bone marrow cell transplantation in clinical perspective. J. Mol. Cell. Cardiol., 38: 225-235.
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  88. Xiao, Y.F., J.Y. Min and J.P. Morgan, 2004. Immunosuppression and xenotransplantation of cells for cardiac repair. Ann. Thor. Surg., 77: 737-744.
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  89. Niagara, M.I., H.K. Haider, L. Ye, V.S. Koh and Y.T. Lim et al., 2004. Autologous skeletal myoblasts transduced with a new adenoviral bicistronic vector for treatment of hind limb ischemia. J. Vascular Surg., 40: 774-785.
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  90. Lei, Y., K.H. Haider, S. Jiang and E.K.W. Sim, 2004. Therapeutic angiogenesis: Devising new strategies based on past experiences. Basic. Res. Cardiol., 99: 121-132.
  91. Law, P.K., K. Haider, G. Fang, S. Jiang, F. Chua, Y.T. Lim and E. Sim, 2004. Human VEGF165-myoblasts produce concomitant angiogenesis/myogenesis in the regenerative heart. Mol. Cell. Biochem., 263: 173-178.
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  92. Idris, N.M., H.K. Haider, M.W. Goh and E.K. Sim, 2004. Therapeutic angiogenesis for treatment of peripheral vascular disease. Growth Factors, 22: 269-279.
    CrossRef  |  Direct Link  |  
  93. Heng, B.C., T. Cao, H.K. Haider, D.Z.M. Wang, E.K.W. Sim and S.C. Ng, 2004. An overview and synopsis of techniques for directing stem cell differentiation in vitro. Cell Tissue Res., 315: 291-303.
    CrossRef  |  Direct Link  |  
  94. Heng, B.C., H.K. Haider, E.K.W. Sim, T. Cao and S.C. Ng, 2004. Strategies for directing the differentiation of stem cells into the cardiomyogenic lineage in vitro. Cardiovascular Res., 62: 34-42.
    CrossRef  |  Direct Link  |  
  95. Haider, K.H., Y. Lei, S. Jiang and E.K.W. Sim, 2004. Therapeutic angiogenesis for the treatment of post-infarction heart through VEGF delivery. Asian Cardiovasc Thorac Ann., 12: 123-131.
  96. Haider, K.H., S.J. Jiang, S. Aziz, Y. Lei, P.K. Law and E.K.W. Sim, 2004. Effectiveness of transient immunosupression using cyclosporine for xenomyoblast transplantation for cardiac repair. Trans. Proceed, 36: 232-235.
    CrossRef  |  Direct Link  |  
  97. Haider, H.K., L. Ye, S. Jiang, R. Ge and P.K. Law et al., 2004. Angiomyogenesis for cardiac repair using human myoblasts as carriers of human vascular endothelial growth factor. J. Mol. Med., 82: 539-549.
    CrossRef  |  Direct Link  |  
  98. Haider, H.K., A.C. Tan, S. Aziz, J.C. Chachques and E.K. Sim, 2004. Myoblast transplantation for cardiac repair: A clinical perspective. Mol. Therapy, 9: 14-23.
    CrossRef  |  Direct Link  |  
  99. Ashraf, M. and K.H. Haider, 2004. Stemming myocardial damage with stem cells: An overview. J. Mol. Cell. Cardiol., 37: 367-367.
  100. Ye, L., H.K. Haider, S. Jiang, R. Ge, P.K. Law and E.K. Sim, 2003. High efficiency transduction of human VEGF 165 into human skeletal myoblasts: In vitro studies. Exp. Mol. Med., 35: 412-420.
    Direct Link  |  
  101. Sim, E.K.W., K.H. Haider and P.K. Law, 2003. Single skeletal muscle transplantation or the purified myoblast engraftment. J. Thoracic Cardiovasc Surg., 125: 118-182.
    CrossRef  |  Direct Link  |  
  102. Sim, E.K., S. Jiang, L. Ye, Y.L. Lim, O.C. Ooi and K.H. Haider, 2003. Skeletal myoblast transplant in heart failure. J. Cardiac Surg., 18: 319-327.
    CrossRef  |  Direct Link  |  
  103. Lei, Y., H.K. Haider, W. Chusnsheng, C. Zhiqiang, C. Hao, H. Kejian and Z. Qiang, 2003. Dose-dependent effect of aprotinin on aggravated pro-inflammatory cytokines in patients with pulmonary hypertension following cardiopulmonary bypass. Cardiovascular Drugs Therapy, 17: 343-348.
    CrossRef  |  Direct Link  |  
  104. Kim, C.K., E.J. Choi, S.H. Choi, J.S. Park, K.H. Haider and W.S. Ahn, 2003. Enhanced p53 gene transfer to human ovarian cancer cells using the cationic nonviral vector, DDC. Gynecol. Oncol., 90: 265-272.
    CrossRef  |  Direct Link  |  
  105. Jiang, S.J., K.H. Haider, Y. Lei, T. Ming and G. Fang et al., 2003. Xenotransplantation of human skeletal myoblasts shows long-term survival in a porcine heart. ASEAN Heart J., 10: 31-36.
  106. Haider, K.H., Y. Lei, S.J. Jiang and E.K.W. Sim, 2003. Cellular myocardial reconstruction using human myoblasts. J. Am. Coll. Cardiol., 42: 589-589.
    CrossRef  |  Direct Link  |  
  107. Haider, K.H., Lei, Y., S.J. Jiang, P.K. Law and E.K.W. Sim, 2003. Avoiding compliance with histocompatibility dogma using immuno-privileged cell xenografts. Ann. Thoracic. Surg., 337: 339-340.
  108. Haider, H.K., J. Shujia, Y. Lei, P.K. Law and E.K. Sim, 2003. Myoblast transplantation for cardiac repair using transient immunosuppression. BAM-PADOVA, 13: 45-52.
    Direct Link  |  
  109. Kim, C.K., K.H. Haider, E.J. Choi, S.J. Choi and W.S. Ahn, 2002. Non-viral vector for efficient gene transfer to human ovarian adenocarcinoma. Gynae Oncol., 84: 85-93.
  110. Kim, C.K., K.H. Haider and S.J. Lim, 2001. Gene medicine : A new field of molecular medicine. Arch Pharm. Res., 24: 1-15.
    PubMed  |  
  111. Haider, K.H., M. Ilyas and Q. Hyder, 2001. Lung perfusion imaging and Tc99m-macroaggregated human serum albumin (Tc99m-MAA). Korean J. Pharm., 31: 73-80.
  112. Haider, K.H. and W.H. Stimson, 1998. Cardiac troponin-I (cTn-I) specific monoclonal antibodies for the assessment of cardiac myocyte damage in an experimental brain-dead pig model. Saudi Pharm J., 6: 140-144.

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